Rak nerki
Objawy

Rak nerki (carcinoma renis, RCC) jest złośliwym nowotworem nabłonkowym nerek, stanowiącym jedno z dziesięciu najczęstszych nowotworów u dorosłych, z predylekcją do mężczyzn (2:1) i średnim wiekiem diagnozy około 64 lat. Wczesne stadia choroby są zazwyczaj bezobjawowe, a rozpoznanie często następuje przypadkowo podczas badań obrazowych. Klasyczna triada objawów (krwiomocz, ból w boku, wyczuwalny guz) występuje u mniej niż 15% pacjentów. Zaawansowane stadium może manifestować się objawami ogólnoustrojowymi, takimi jak gorączka, nocne poty, obrzęki, nadciśnienie tętnicze, niedokrwistość, hiperkalcemia oraz objawami przerzutów do płuc, kości, mózgu czy wątroby. U 20-30% chorych obserwuje się zespoły paraneoplastyczne, w tym hiperkalcemię, erytrocytozę i zespół wyniszczenia nowotworowego.

Objawy raka nerki (Rak nerki)

Rak nerki (łac. carcinoma renis), znany również jako rak nerkowokomórkowy (RCC), jest nowotworem złośliwym wywodzącym się z komórek nabłonkowych nerek. Jest to jeden z dziesięciu najczęstszych nowotworów występujących zarówno u mężczyzn, jak i kobiet. Rak nerki dotyka około dwukrotnie częściej mężczyzn niż kobiety, a średni wiek pacjentów w momencie diagnozy wynosi około 64 lata12. Każdego roku w Stanach Zjednoczonych diagnozuje się ponad 75 000 nowych przypadków tego nowotworu3.

Objawy wczesnego stadium raka nerki

Szczególnym wyzwaniem w przypadku raka nerki jest fakt, że we wczesnych stadiach choroby zazwyczaj nie powoduje on żadnych wyraźnych objawów. Większość przypadków raka nerki jest wykrywana przypadkowo podczas badań obrazowych wykonywanych z innych powodów45. U około 25-30% pacjentów w momencie rozpoznania nowotwór już rozprzestrzenił się poza nerkę6.

Gdy pojawiają się objawy, mogą one obejmować:

  • Krew w moczu (krwiomocz) – jest to najczęstszy objaw raka nerki. Mocz może przybierać kolor różowy, czerwony lub przypominający colę17
  • Ból w okolicy lędźwiowej lub boku, który nie ustępuje8
  • Wyczuwalny guz lub masa w jamie brzusznej lub okolicy nerki4
  • Zmęczenie lub uczucie osłabienia9
  • Utrata apetytu1
  • Niewyjaśniona utrata masy ciała8

Warto podkreślić, że obecność tych objawów nie oznacza jednoznacznie raka nerki, gdyż mogą one występować również w innych, łagodnych schorzeniach układu moczowego, takich jak zakażenie dróg moczowych czy kamica nerkowa79.

Klasyczna triada objawów

Klasyczna triada objawów raka nerki obejmuje:

  • Krwiomocz
  • Ból w boku
  • Wyczuwalny guz w jamie brzusznej

Jednak ta charakterystyczna konstelacja objawów występuje jedynie u mniej niż 15% pacjentów10. Wiele przypadków raka nerki pozostaje bezobjawowych, dopóki nowotwór nie osiągnie znacznych rozmiarów lub nie rozprzestrzeni się do innych narządów11.

Objawy zaawansowanego raka nerki

W miarę rozwoju choroby i rozprzestrzeniania się nowotworu poza nerkę mogą pojawić się dodatkowe objawy związane z zajęciem innych narządów i układów. Objawy zaawansowanego raka nerki mogą obejmować:

  • Uporczywa gorączka niezwiązana z infekcją4
  • Nocne poty4
  • Obrzęk nóg i kostek – może wystąpić, gdy guz uniemożliwia nerce usuwanie nadmiaru płynów z organizmu12
  • Nadciśnienie tętnicze – nerki odgrywają kluczową rolę w regulacji ciśnienia krwi13
  • Niedokrwistość (anemia) – niska liczba czerwonych krwinek8
  • Podwyższony poziom wapnia we krwi (hiperkalcemia)14
  • Policytemię (zwiększona liczba czerwonych krwinek)14
  • U mężczyzn – powiększenie żył wokół jądra (żylaki powrózka nasiennego), szczególnie po prawej stronie15

W przypadku przerzutów raka nerki do innych narządów mogą pojawić się dodatkowe objawy zależne od lokalizacji zmian przerzutowych16:

  • Przerzuty do płuc – uporczywy kaszel, odkrztuszanie krwi, duszność17
  • Przerzuty do kości – ból kości, patologiczne złamania18
  • Przerzuty do mózgu – bóle głowy, zaburzenia widzenia, splątanie, drgawki19
  • Przerzuty do wątroby – żółtaczka, nieprawidłowe wyniki testów funkcji wątroby20

Zespoły paraneoplastyczne w raku nerki

U około 20-30% pacjentów z rakiem nerki mogą wystąpić zespoły paraneoplastyczne – objawy niezwiązane bezpośrednio z fizycznym oddziaływaniem guza, ale wynikające z substancji wydzielanych przez komórki nowotworowe1821. Najczęstsze zespoły paraneoplastyczne w raku nerki obejmują:

  • Hiperkalcemię (podwyższony poziom wapnia we krwi) – może powodować osłabienie, zmęczenie, spowolnienie reakcji i zaparcia14
  • Erytrocytozę (zwiększoną produkcję czerwonych krwinek) – spowodowaną nadmiernym wydzielaniem erytropoetyny14
  • Zespół wyniszczenia nowotworowego – charakteryzujący się utratą masy ciała, anoreksją i ogólnym osłabieniem17
  • Nadciśnienie tętnicze oporne na leczenie22
  • Nieprawidłowe wyniki testów wątrobowych18

Progresja raka nerki

Rak nerki rozwija się poprzez szereg stadiów, które definiują jego zaawansowanie i potencjalne rokowanie. System klasyfikacji TNM (Tumor – guz, Node – węzły chłonne, Metastasis – przerzuty) jest używany do określenia stadium zaawansowania raka nerki23.

Stadia zaawansowania raka nerki

Rozpoznanie stadium raka nerki jest kluczowe dla określenia rokowania i planowania leczenia24:

  • Stadium I: Guz o wielkości do 7 cm znajduje się tylko w nerce. Rak jest całkowicie ograniczony do nerki2425
  • Stadium II: Guz jest większy niż 7 cm, ale nadal ograniczony tylko do nerki24
  • Stadium III: Nowotwór rozszerza się na główne żyły lub tkanki otaczające, ale nie poza powięź Geroty. Może również oznaczać, że rak rozprzestrzenił się do pobliskich węzłów chłonnych24
  • Stadium IV: Nowotwór rozrósł się poza nerkę. Oznacza to również, że rak mógł rozprzestrzenić się do innych części ciała, takich jak kości, wątroba, płuca lub mózg242

Rokowanie w raku nerki

Rokowanie w raku nerki jest ściśle powiązane ze stadium zaawansowania choroby w momencie diagnozy24. Ogólny wskaźnik pięcioletniego przeżycia dla raka nerki wynosi około 75% w Stanach Zjednoczonych10.

Wskaźniki przeżycia pięcioletniego w zależności od stadium:

  • Stadium I: około 90-93%2623
  • Stadium II: około 75-80%27
  • Stadium III: około 60-70%10
  • Stadium IV: około 12-15%1026

W przypadku raka ograniczonego do nerki (lokalnego), pięcioletnie przeżycie wynosi około 93%. Jeśli choroba rozprzestrzeniła się na okoliczne węzły chłonne, wskaźnik ten spada do około 70%, a w przypadku przerzutów odległych – do około 12%10.

Czynniki wpływające na progresję raka nerki

Tempo progresji raka nerki może być różne u poszczególnych pacjentów i zależy od wielu czynników8:

  • Typ histologiczny guza – różne podtypy raka nerki charakteryzują się odmienną agresywnością i potencjałem przerzutowania28
  • Stopień złośliwości (ang. grade) – określa, jak bardzo komórki nowotworowe różnią się od prawidłowych komórek i jak szybko mogą rosnąć29
  • Molekularne markery prognostyczne – określone zmiany genetyczne mogą wpływać na przebieg choroby26
  • Ogólny stan zdrowia pacjenta i współistniejące choroby16
  • Odpowiedź na zastosowane leczenie30

Rak nerki wykazuje tendencję do nawrotów, nawet po skutecznym leczeniu. Ryzyko nawrotu jest najwyższe w ciągu pierwszych kilku lat po leczeniu, szczególnie w przypadku guzów o wysokim stopniu złośliwości lub zaawansowanym stadium16.

Grupy wysokiego ryzyka zachorowania na raka nerki

Istnieją określone grupy pacjentów, którzy powinni być szczególnie wyczuleni na objawy raka nerki ze względu na zwiększone ryzyko zachorowania1:

  • Osoby w wieku powyżej 60 lat1
  • Mężczyźni (chorują około dwukrotnie częściej niż kobiety)1
  • Palacze tytoniu1
  • Osoby z otyłością1
  • Pacjenci z nadciśnieniem tętniczym1
  • Osoby z przewlekłą chorobą nerek lub po przeszczepie nerki3132
  • Pacjenci długotrwale dializowani (około 5-krotnie zwiększone ryzyko)33
  • Osoby z dziedzicznymi zespołami zwiększającymi ryzyko raka nerki (np. zespół von Hippla-Lindaua)1
  • Osoby z rodzinnym występowaniem raka nerki1

Znaczenie wczesnej diagnostyki

Wczesne wykrycie raka nerki ma kluczowe znaczenie dla rokowania pacjenta. Nowotwory wykryte we wczesnym stadium, zanim rozprzestrzenią się poza nerkę, mają znacznie lepsze rokowanie i często mogą być całkowicie wyleczone83.

Niestety, ze względu na brak charakterystycznych objawów we wczesnych stadiach, rak nerki często jest wykrywany przypadkowo podczas badań obrazowych wykonywanych z innych powodów4. Z tego powodu ważne jest, aby osoby z grupy podwyższonego ryzyka regularnie konsultowały się z lekarzem i zgłaszały wszelkie niepokojące objawy, nawet jeśli wydają się one łagodne lub niespecyficzne34.

Każdy, kto zauważy krew w moczu, nawracający ból w okolicy lędźwiowej lub inne niepokojące objawy, powinien jak najszybciej skonsultować się z lekarzem w celu przeprowadzenia odpowiedniej diagnostyki4. Wczesne wykrycie i leczenie raka nerki znacząco zwiększa szanse na pełne wyleczenie3.

Objawy raka nerki – kluczowe informacje

Rak nerki często rozwija się bezobjawowo we wczesnych stadiach, co stanowi wyzwanie diagnostyczne. Gdy pojawiają się objawy, mogą one być niespecyficzne i przypominać inne, łagodniejsze schorzenia układu moczowego12.

Najczęstsze objawy raka nerki to:

  • Krwiomocz – najczęstszy objaw, może być widoczny gołym okiem (makroskopowy) lub tylko w badaniu laboratoryjnym (mikroskopowy)5
  • Ból w okolicy lędźwiowej lub boku – często tępy, uporczywy, niezwiązany z urazem35
  • Wyczuwalny guz w jamie brzusznej lub okolicy nerki36
  • Zmęczenie i osłabienie8
  • Utrata apetytu i niewyjaśniona utrata masy ciała9
  • Gorączka niezwiązana z infekcją37
  • Nocne poty4
  • Obrzęk nóg i kostek12
  • Nadciśnienie tętnicze5
  • Niedokrwistość5

W zaawansowanych stadiach, gdy nowotwór rozprzestrzenia się do innych narządów, mogą pojawić się dodatkowe objawy zależne od lokalizacji przerzutów16.

Należy pamiętać, że obecność tych objawów nie musi oznaczać raka nerki, ale wymaga konsultacji lekarskiej w celu wykluczenia poważnych schorzeń. Wczesne wykrycie i leczenie raka nerki znacząco zwiększa szanse na pełne wyleczenie8.

Kolejne rozdziały

Zapraszamy do dalszego czytania naszego leksykonu.

Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.

  1. 10.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Kidney cancer – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/kidney-cancer/symptoms-causes/syc-20352664
    Kidney cancer is a growth of cells that starts in the kidneys. […] Kidney cancer doesn’t usually cause symptoms at first. In time, signs and symptoms may develop, including: Blood in the urine, which may appear pink, red or cola colored. Loss of appetite. Pain in the side or back that doesn’t go away. Tiredness. Unexplained weight loss. […] Unfortunately, kidney cancer is often hard to diagnose, as it doesn’t have clear signs or symptoms in its early stages. Over time, the following may develop: Blood in your urine, which may appear pink, red or cola colored. Pain in your back or side that does not go away. Loss of appetite. Unexplained weight loss. Persistent tiredness. Fever. Or night sweats. […] The average age of those diagnosed with kidney cancer is 64. It is about twice as common in men as it is in women. […] The risk of kidney cancer increases with age. […] Factors that may increase the risk of kidney cancer include: Older age. Smoking tobacco. Obesity. High blood pressure. Certain inherited conditions. Family history of kidney cancer.
  • #2 Stage 4 Kidney Cancer: Metastatic Symptoms & Life Expectancy
    https://www.cancercenter.com/cancer-types/kidney-cancer/types/metastatic-stage-4-kidney-cancer
    Kidney cancer, also called renal cancer, is an abnormal, spreading growth that develops in the kidneys. Stage 4 kidney cancer occurs when this growth spreads beyond the kidney to the adrenal glands, lymph nodes or other organs. Its also known as metastatic kidney cancer. […] Stage 4 kidney cancer is when this mass of cancerous cells spreads beyond the layer of fatty tissue around the kidney into the adrenal glands, nearby lymph nodes or other organs. […] Stage 4 renal cancer may be treatable, but it has a low survival rate. Some patients opt for palliative treatments to help reduce symptoms and lengthen life. […] Metastatic kidney cancer has some specific symptoms that vary from early-stage kidney cancer symptoms. About half of people with kidney cancers may have no signs or symptoms.
  • #3 Kidney Cancer Symptoms You Shouldn’t Ignore | Fox Chase Cancer Center – Philadelphia PA
    https://www.foxchase.org/blog/kidney-cancer-symptoms-you-shouldnt-ignore
    Kidney cancer is among the top 10 most common cancers in the U.S. today and rates are rising. According to the American Cancer Society, more than 80,000 people were diagnosed with the disease in 2024. […] Finding kidney cancer early can significantly improve your chances of survival. While every patient’s cancer journey is unique, when kidney cancer is caught before it can spread to other parts of the body, more than 90% of patients survive for at least five years. […] But early detection can be a challenge. Kidney cancer often doesn’t cause symptoms in its earliest stages. And when signs of the disease start, they often overlap with signs and symptoms of other common health conditions. […] Most people won’t have symptoms of kidney cancer until it spreads, in part because the kidneys are located deep inside the body. But there are some telltale markers to look out for: Blood in the urine. Middle-back pain on one side. Unexplained weight loss. An unexplained fever that lingers. Loss of appetite. A lump in the stomach area, side, or lower back. Anemia (low red blood cell levels). Night sweats. Fatigue.
  • #4 Symptoms of kidney cancer – NHS
    https://www.nhs.uk/conditions/kidney-cancer/symptoms/
    Often there are no obvious symptoms of kidney cancer. Its usually diagnosed when testing for something else. […] When there are symptoms, they can include: blood in your pee, a lump or swelling in your back, under your ribs, or in your neck, pain between your ribs and waist that does not go away, loss of appetite or losing weight without trying to, feeling tired or having no energy, a high temperature that does not go away, sweating a lot, including at night. […] Its important to get help as soon as possible as the symptoms can be similar to a kidney infection, which can be serious if it’s not treated quickly. […] Some of these symptoms are common and can be caused by many different conditions. Having them does not definitely mean you have kidney cancer. But it’s important to get them checked by a GP. […] This is because if they’re caused by cancer, finding it early can mean its more treatable. […] You may get an urgent referral for more tests or to see a specialist in hospital if the GP thinks you have symptoms that could be cancer. This does not definitely mean you have cancer.
  • #5 Symptoms of kidney cancer | Cancer Research UK
    https://www.cancerresearchuk.org/about-cancer/kidney-cancer/symptoms
    Most people who are diagnosed with kidney cancer do not have any symptoms. […] When someone does have symptoms, these might include: blood in the urine, a lump or mass in the kidney area, a pain in the side between the ribs and the hip (flank). […] Blood in the urine (called haematuria) is the most common symptom of kidney cancer. […] A lump or swelling in the area of your kidneys should prompt a visit to your doctor. […] A pain in the side between your ribs and the hip (flank) can be a sign of kidney cancer. […] Some people have other symptoms which can be vague, including weight loss, a high temperature and very heavy sweating, tiredness, loss of appetite, and a general feeling of poor health. […] High blood pressure and having fewer red blood cells than normal (anaemia) can also be symptoms of kidney cancer. […] You should see your doctor if you have blood in your urine, a lump or mass in your kidney area, a pain in the side between your ribs and the hip (flank), or any other symptoms of kidney cancer that don’t go away.
  • #6 Clinical presentation, diagnosis, and staging of renal cell carcinoma – UpToDate
    https://www.uptodate.com/contents/clinical-presentation-diagnosis-and-staging-of-renal-cell-carcinoma
    Patients with RCC can present with a range of symptoms; unfortunately, many patients are asymptomatic until the disease is advanced. At presentation, approximately 25 percent of individuals either have distant metastases or advanced locoregional disease. […] In one review of 309 consecutive patients with RCC, the most common presenting symptoms were hematuria, abdominal mass, pain, and weight loss. In contemporary series, fewer patients have the typical symptoms and there is an increased frequency of incidental diagnosis due to radiologic procedures performed for other indications.
  • #7 7 Top Kidney Cancer Symptoms & Signs | MD Anderson Cancer Center
    https://www.mdanderson.org/cancer-types/kidney-cancer/kidney-cancer-symptoms.html
    Due to the location of the kidneys, many kidney cancer symptoms don’t show until the tumor has grown quite large. Most are found during treatment for other medical conditions, such as kidney stones or back pain. If there are symptoms, they vary from person to person. […] Kidney cancer symptoms may include: […] Blood in the urine, known as hematuria. This is the most common kidney cancer symptom. Often, hematuria causes the urine to appear rusty or deep red. Other times, it cannot be seen by the naked eye. Hematuria is not a sure sign of kidney cancer, since it can be caused by other medical problems like a kidney stone or urinary tract infection. Every person with hematuria should see a doctor. […] A lump or mass on the side or lower back […] Unexplained fever for a few weeks […] Unintentional weight loss
  • #8 Kidney Cancer: Symptoms, Signs, Causes & Treatment
    https://my.clevelandclinic.org/health/diseases/9409-kidney-cancer-overview
    Kidney cancer may not produce any noticeable symptoms in its early stages. But as the tumor grows, symptoms may begin to appear. For that reason, kidney cancer often isn’t diagnosed until it has begun to spread. […] Kidney cancer symptoms may include: Blood in your pee (hematuria). A lump or mass in your kidney area. Flank pain. Tiredness. A general sense of not feeling well. Loss of appetite. Weight loss. Low-grade fever. Bone pain. High blood pressure. Anemia. High calcium. […] Your kidney cancer prognosis depends on the type and stage of cancer (whether it’s just in your kidney or has spread to other places in your body). The chance of recovery also depends on your general state of health. […] Like most cancers, kidney cancer is most treatable when found in its early stages. In general, if the cancer is detected early, before it breaks through the outer covering of your kidney, kidney cancer is often curable.
  • #9 Signs and Symptoms of Kidney Cancer | Renal Cancer Signs | American Cancer Society
    https://www.cancer.org/cancer/types/kidney-cancer/detection-diagnosis-staging/signs-and-symptoms.html
    Early kidney cancers often dont cause any signs or symptoms, but larger or more advanced ones might. Some possible signs and symptoms of kidney cancer include: Blood in the urine (hematuria) […] Low back pain on one side (not caused by injury) […] A mass (lump) on the side or lower back […] Fever that is not caused by an infection and that doesnt go away […] Fatigue (feeling very tired) […] Loss of appetite […] Weight loss […] Anemia (low red blood cell counts). These signs and symptoms can be caused by kidney cancer (or another type of cancer), but more often they are caused by other, benign (non-cancerous) diseases. For example, blood in the urine is most often caused by a bladder or urinary tract infection or a kidney stone. Still, if you have any of these symptoms, see a doctor so that the cause can be found and treated, if needed.
  • #10 Kidney cancer – Wikipedia
    https://en.wikipedia.org/wiki/Kidney_cancer
    Symptoms may include blood in the urine, a lump in the abdomen, or back pain. […] Fever, weight loss, and tiredness may also occur. […] As kidney cancer becomes more advanced it classically results in blood in the urine, flank or back pain, and a mass. […] Other symptoms that are consistent with advanced disease include weight loss, fever, night sweats, palpable swollen lymph nodes in the neck, non-reducing varicocele, bone pain, continuous cough, and bilateral lower leg swelling. […] The classic triad of visible blood in the urine (hematuria), flank pain and palpable abdominal mass occurs in less than 15% of the cases. […] Kidney cancer newly affected about 403,300 people and resulted in 175,000 deaths globally in 2018. […] The overall five-year survival rate is 75% in the United States, 71% in Canada, 70% in China, and 60% in Europe. […] For cancers that are confined to the kidney, the five-year survival rate is 93%, if it has spread to the surrounding lymph nodes it is 70%, and if it has spread widely, it is 12%.
  • #11 How Common is Kidney Cancer? Detection and screening remain elusive – Saint John’s Cancer Institute Blog
    https://www.saintjohnscancer.org/blog/how-common-is-kidney-cancer-detection-and-screening-remain-elusive/
    Unlike many other types of cancers that may affect us in our lifetime, kidney cancer can be challenging to detect. Without a clear set of symptoms, which could be mistaken for other problems, there is no screening mechanism for kidney cancer. […] There are physical symptoms that could be a sign of kidney cancer that can manifest separately or together, including rust or pink-colored blood in the urine, pain in the side and black that doesnt go away, unexplained weight loss, and feeling very tired. […] Kidney cancer can often be cured if diagnosed and treated when it is still localized to the kidney. […] The bigger the tumor, the higher the risk that you might have cancer [spread] outside the kidney. […] Kidney cancer, also known as renal cancer, varies in how quickly it spreads depending on its type and stage at diagnosis.
  • #12 7 Top Kidney Cancer Symptoms & Signs | MD Anderson Cancer Center
    https://www.mdanderson.org/cancer-types/kidney-cancer/kidney-cancer-symptoms.html
    Lingering dull ache or pain in the side, abdomen or lower back […] Feeling fatigued or in poor health […] Swelling of ankles and legs. This symptom arises when the kidney tumor prevents the kidney from removing excess fluid in the body. […] These symptoms do not always mean you have kidney cancer. However, it is important to discuss any symptoms with your doctor, since they may signal other health problems.
  • #13 Kidney Cancer: Signs and Symptoms | Banner MD Anderson
    https://www.bannerhealth.com/services/cancer/cancer-type/kidney-cancer/symptoms
    With kidney cancer, you might not feel hungry. Or you might feel full after eating a small amount of food. […] Your kidneys help your body make red blood cells, so you may have low amounts of red blood cells if you have kidney cancer. […] With more advanced cancer, you may notice: […] Swelling in the legs or ankles, since the tumor may be making it hard for your kidneys to remove fluid from your body. […] High blood pressure, since your kidneys help regulate your blood pressure. […] A fever thats not caused by an infection. It may be long-lasting or may come and go. […] A mass or lump in the abdomen or side that you can feel, if the kidney tumor is large. […] Generally feeling unwell.
  • #14 Kidney Cancer – Kidney and Urinary Tract Disorders – Merck Manual Consumer Version
    https://www.merckmanuals.com/home/kidney-and-urinary-tract-disorders/cancers-of-the-kidney-and-genitourinary-tract/kidney-cancer
    Conversely, kidney cancer may lead to a drop in the red blood cell count (anemia) because of slow bleeding into the urine. Anemia may cause easy fatigability or dizziness. […] Some people develop high levels of calcium in the blood (hypercalcemia), which may cause weakness, fatigue, slowed reaction times, and constipation. […] Blood pressure may increase, but high blood pressure may not cause symptoms.
  • #14 Kidney Cancer – Kidney and Urinary Tract Disorders – Merck Manual Consumer Version
    https://www.merckmanuals.com/home/kidney-and-urinary-tract-disorders/cancers-of-the-kidney-and-genitourinary-tract/kidney-cancer
    Kidney cancer may cause blood in the urine, pain in the side, or fever. […] Symptoms may not occur until the cancer has spread (metastasized) or become very large. Blood in the urine is the most common first symptom, but the amount of blood may be so small that it can be detected only under a microscope. On the other hand, the urine may be visibly red. […] The next most common symptoms are pain in the area between the ribs and hip (the flank), fever, and weight loss. Infrequently, a kidney cancer is first detected when a doctor feels an enlargement or lump in the abdomen. Nonspecific symptoms of kidney cancer include fatigue, weight loss, and early satiety (feeling of fullness after a meal). […] The red blood cell count may become abnormally high (polycythemia) because high levels of the hormone erythropoietin (which is produced by the diseased kidney or by the tumor itself) stimulate the bone marrow to increase the production of red blood cells.
  • #15 Renal cell carcinoma: MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/000516.htm
    Renal cell carcinoma is a type of kidney cancer that starts in the lining of very small tubes (tubules) in the kidney. […] Renal cell carcinoma is the most common type of kidney cancer in adults. It occurs most often in men 60 to 70 years old. […] Symptoms of this cancer may include any of the following: Abdominal pain and swelling, Back pain, Blood in the urine, Swelling of the veins around a testicle (varicocele), Flank pain, Weight loss, Fever, Liver dysfunction, Elevated erythrocyte sedimentation rate (ESR), Excessive hair growth in females, Pale skin, Vision problems. […] Sometimes, both kidneys are involved. The cancer spreads easily, most often to the lungs and other organs. In about one fourth of people, the cancer has already spread (metastasized) at the time of diagnosis. […] How well someone with kidney cancer does depends on how much the cancer has spread and how well treatment works. The survival rate is highest if the tumor is in the early stages and has not spread outside the kidney. If it has spread to the lymph nodes or to other organs, the survival rate is much lower.
  • #16 Stage 4 Kidney Cancer: Metastatic Symptoms & Life Expectancy
    https://www.cancercenter.com/cancer-types/kidney-cancer/types/metastatic-stage-4-kidney-cancer
    Symptoms of advanced renal cancer include: Fever, Weight loss, Cough, Large or swollen lymph nodes, Enlarged veins in the right side of the scrotum, Swelling of the legs and feet, Paraneoplastic syndrome (high blood pressure, high calcium levels and too many red blood cells), Blood in the urine (also called hematuria). […] The disease may also spread to other organs before a person is diagnosed. Stage 4 kidney cancer tends to recur quickly, even after successful treatment. […] The survival rate for metastatic kidney cancer depends on a variety of factors, including the patients age, overall health and the extent of the disease. Patients should always talk to their care team about their individual prognosis.
  • #17 Don’t ignore these symptoms of kidney cancer | UCLA Health
    https://www.uclahealth.org/news/article/dont-ignore-these-symptoms-of-kidney-cancer
    If your kidney is enlarged or has a growth, it could cause a mass or bulge on the side of your abdomen. […] When kidney cancer is advanced, you may feel an actual protrusion or an unusually firm and thickened area. […] Symptoms of these syndromes vary but may include: Fever, Loss of appetite, High calcium, Increased or decreased blood cell or platelet count, shown on a blood test. […] Kidney cancer can metastasize (spread) to any part of the body through the blood or lymphatic system. […] Instead, metastatic kidney cancer may cause symptoms in the newly affected areas of the body including: Lungs, causing cough and shortness of breath; Bones, resulting in bone pain or fracture; Brain, presenting as headaches, confusion or seizures. […] If you have any symptoms associated with kidney cancer, talk to your primary care provider.
  • #18 Azthena logo with the word Azthena
    https://www.news-medical.net/health/Kidney-Cancer-Symptoms.aspx
    Most patients with kidney cancer do not have symptoms. This is especially true in early stages of cancer when the tumor is small. But the affected kidneys grow in size and the tumour may grow through the wall of the kidney and invade nearby tissues and organs. This results in several signs and symptoms of the condition. […] Symptoms include: Presence of blood in urine. This called haematuria and may be painless. The episodes of haematuria may 'come and go’ as the tumour bleeds. This is the first symptom in around 60% of all cases. Pain in the sides of the body or the back just below the ribs. A feeling of a lump in the abdomen. This could manifest as swelling of the abdomen. High blood pressure. Loss of appetite and increased thirst. Feeling tired and fatigued. There may be night sweats or increased perspiration at nights during sleep. High fever for a long duration with temperatures over 38C (100.4F). This fever is not usually explained by a cause and is called pyrexia of unknown origin. Unexplained weight loss. Anemia with too little blood and associated symptoms such as being pale and tired. There may be polycythemia in some individuals this means too much blood in body. Varicocele or presence of engorged and convoluted network of veins in the scrotum is seen in some cases. Both sided edema and swelling of the ankles. Excessive hair growth in females. If the cancer has spread to the liver there may be jaundice and other features of liver damage like raised liver enzymes, ascitis etc. If the cancer has spread to the bones there may be pathological and easy fractures. Hip fractures are commonly seen. If the cancer has spread to the lungs there may be presence of blood in the sputum. Paraneoplastic symptoms may occur in approximately 20-30% of patients. These include involvement of nerves, anemia, polycythemia, amyloidosis, elevated ESR, hypercalcaemia (raised blood calcium levels) and abnormal liver function tests.
  • #19 Renal Cell Carcinoma: What to Expect with Kidney Cancer
    https://www.verywellhealth.com/renal-cell-carcinoma-symptoms-causes-diagnosis-and-treatment-4772120
    Your first symptoms may be caused by the effects of metastatic cancer in a different part of your body besides your kidney: Back pain can occur due to renal cell carcinoma metastasis to the spine, Breathing problems or feeling faint can occur due to the spread of renal cell carcinoma to the lungs or heart, Headaches or weakness on one side of the body, Behavioral changes, confusion, or seizures can occur if renal cell carcinoma spreads to the brain. […] Renal cell carcinoma is a type of kidney cancer that may cause a variety of symptoms, including abdominal pain, flank pain, and blood in urine.
  • #20 What are the symptoms of kidney cancer? – Action Kidney Cancer
    https://actionkidneycancer.org/kidney-cancer/newly-diagnosed/what-are-the-symptoms-of-kidney-cancer/
    Unfortunately, 25-30% of people with kidney cancer have symptoms of cancer that has spread, such as; a persistent cough, frequent headaches, bone pain, or abnormal liver function tests. […] These symptoms can be caused by many other conditions, apart from kidney cancer, so it is important to have them checked out by a doctor.
  • #21 Renal Cell Carcinoma Symptoms, Metastasis, Treatment & Life Expectancy
    https://www.emedicinehealth.com/renal_cell_cancer/article_em.htm
    Symptoms such as a mass that can be felt in the flank, pain in the kidney region, or weight loss are usually signs of advanced cancer. […] The early kidney cancers are usually asymptomatic, and either detected incidentally while testing for some other condition or because blood is found in the urine, which may or may not be visible to the patient. […] Other symptoms may result from metastatic renal cell cancer in the bones, lungs, or elsewhere. […] If the disease attacks the bones, for example, it can cause bone pain, which is deep and achy. […] Renal cell cancer can also cause several conditions called paraneoplastic syndromes. […] These are problems caused by the tumor when it releases cytokines (chemicals involved with the immune system) or hormones. […] Symptoms such as blood in the urine, pain in the side that will not go away, a lump in the side or belly, unexplained fevers, weight loss, and night sweats may indicate the need to seek medical care.
  • #22 How to Detect Kidney Cancer Early: Key Warning Signs and Test – BMCHRC
    https://bmchrc.org/blog/detect-kidney-cancer-early-warning-signs-tests
    Symptoms of a kidney tumor can often overlap with other kidney-related issues, such as infections or stones. Key signs of a kidney tumor include blood in the urine without pain during urination. Persistent pain or pressure in the side or back can also be a symptom. Unexplained fatigue or weakness may occur. High blood pressure that is difficult to control is another indicator. A noticeable mass in the abdominal area may also be present.
  • #23 Kidney Cancer Stages, Treatment by Stage & Survival Rate
    https://www.cancercenter.com/cancer-types/kidney-cancer/stages
    Many early kidney cancers are suspected after a urine sample tests positive for blood, or an imaging test of the abdomen computed tomography (CT) scan, magnetic resonance imaging (MRI) scan or ultrasound reveals a problem. […] The cancer has not spread outside the kidney and isn’t larger than 7 cm. Under the TNM system, stage 1 kidney cancer is T1, N0, M0. […] The cancer has not spread outside the kidney but is larger than 7 cm. Using the TNM system, stage 2 kidney cancer is T2, N0, M0. […] The cancer may be any size, but it has spread to nearby sites outside of the kidney. Using the TNM system, stage 3 kidney cancer is T3, N0, M0 or T1-T3, N1, M0. […] The cancer has spread away from the kidney to distant sites or organs. The most common locations kidney cancer spreads, or metastasizes, to include distant lymph nodes, the lungs, bones, liver and brain. The TNM classification for stage 4 kidney cancer is T4, any N, M0 or any T, any N, M1. […] The best treatment for kidney cancer depends on the stage, along with the patient’s general health. […] If the cancer hasn’t grown outside the kidney, the five-year relative survival rate is 93 percent. For stage 4 kidney cancer, the five-year relative survival rate is much lower.
  • #24 Kidney cancer – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/kidney-cancer/diagnosis-treatment/drc-20352669
    A stage 3 kidney cancer may mean that the tumor in the kidney extends to the surrounding tissue. It also may mean that the cancer has spread to nearby lymph nodes. […] A stage 4 kidney cancer may mean that the tumor has grown beyond the kidney. It also may mean that the cancer has spread to other parts of the body, such as the bones, liver or lungs. […] Kidney cancer diagnosis often begins with a physical exam and a discussion of your health history. Blood and urine tests as well as imaging tests may be used. A sample of tissue may be taken for lab testing. […] The stages of kidney cancer range from 1 to 4. A stage 1 kidney cancer is small and confined to the kidney. As the cancer gets larger, the stages get higher. A stage 4 kidney cancer has grown beyond the kidney or spread to other parts of the body.
  • #24 Kidney cancer – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/kidney-cancer/diagnosis-treatment/drc-20352669
    Patients diagnosed with kidney cancer often want to know what could they have done differently to prevent this from happening in the first place. […] Prognosis for kidney cancer depends upon the stage at which the kidney cancer is discovered. For patients with early stage disease, the prognosis is excellent and the expectation is typically that somebody will be cured of their kidney cancer. For later stage disease, thankfully, we have many new treatments. And even if it’s not possible to cure a patient, the expectation is we will significantly extend their life. […] A stage 1 kidney cancer means that the tumor in the kidney is 2 3/4 inches (7 centimeters) in diameter or smaller. The cancer is only in one kidney and completely contained within it. […] A stage 2 kidney cancer means that the tumor in the kidney is larger than 2 3/4 inches (7 centimeters) in diameter, but it’s still confined to the kidney.
  • #25 Stage 1 kidney cancer: Symptoms, duration, treatment, and more
    https://www.medicalnewstoday.com/articles/stage-1-kidney-cancer
    Cancer stages indicate how much a persons cancer has spread. If the individual has stage 1 kidney cancer, the disease has not spread outside their kidneys. Treatment at this stage may improve a persons outlook. […] The ACS notes that people in the early stages of kidney cancer typically do not experience any symptoms. Instead, symptoms may develop as the tumor grows. […] Possible signs of kidney cancer include: blood in urine, lower back pain on one side that is not due to injury, a lump on the lower back or side, loss of appetite, unexplained weight loss, fever that does not go away and is not due to an infection, fatigue, anemia. […] Healthcare professionals classify stage 1 kidney cancer with the values T1, N0, and M0 using the TNM system. These values indicate that the tumor is 7 centimeters (cm) long or less and has not spread outside the kidney. […] Generally, people with stage 1 kidney cancer have no symptoms. While the outlook for someone with this disease is generally positive, individual factors can affect it. […] Early diagnosis and treatment of stage 1 kidney cancer may improve a persons outlook.
  • #26 Renal Cell Carcinoma: Symptoms, Treatment & Prognosis
    https://my.clevelandclinic.org/health/diseases/24906-renal-cell-carcinoma
    Cancer staging helps your healthcare provider determine how advanced your cancer is. It can show if your cancer is localized or metastatic. This information helps your provider plan treatment. It also helps determine the likely outcomes of your treatment (prognosis). […] Metastatic RCC often spreads to your lymph nodes, lungs, bone, liver and brain. It can also spread to your ovaries or testicles. […] Treatment depends on many factors, including cancer stage and your overall health. Treatment for localized RCC is different from treatments for metastatic RCC. […] It can be, but it depends on your specific diagnosis. People with localized RCC thats been surgically removed generally have a very good long-term prognosis. […] Increasingly, providers are detecting RCC in earlier stages, when the cancer is more treatable. Early detection and better treatments have increased the survival rate. The five-year survival rate for Stage I RCC is 90%. And while the life expectancy for people with Stage IV renal cell carcinoma was once a matter of months, many people are now living for several years.
  • #27 Kidney Cancer: Causes, Symptoms, and Diagnosis
    https://www.healthline.com/health/kidney-cancer
    Kidney cancer doesnt usually cause any symptoms in its early stages when the mass is small. As the cancer progresses, the symptoms may include: persistent back pain, especially just below your ribs […] blood in your urine […] low back pain […] a lump on your side or lower back […] fatigue […] recurring fevers […] loss of appetite […] unexplained weight loss […] anemia. […] The outlook for people with kidney cancer varies. It depends on how quickly the cancer is caught and how it responds to treatment. Approximately 65 percent of kidney and renal pelvis cancers are diagnosed before they have spread. The cancer may spread, or metastasize, to the other kidney. However, its most likely to spread to the lungs. Metastatic cancer can be harder to treat. […] Survival rates for kidney cancer are higher when the condition is treated in its earlier stages. For example, the ACS reports that the observed five-year survival rate for stage 1 kidney cancer is 80 percent. Keep in mind that observed survival rates are estimates. They are based on groups of people. […] The outlook for an individual with kidney cancer can depend on their age, overall health, other health conditions, the stage of the cancer when it is diagnosed, and how far it has spread.
  • #28 Explaining the Different Types of Kidney Cancer  
    https://www.thebhdfoundation.org/living-with-bhd/help-advice/354-explaining-the-different-types-of-kidney-cancer
    There are often very few symptoms of early-stage kidney cancer. Symptoms are often similar regardless of which type of kidney cancer you have. When symptoms do occur, they include blood in your urine, a lump or swelling in your side and pain in the side or back below the ribs. […] Generally, outcomes are good and kidney cancer can be treated successfully. However, the quicker kidney cancer can be identified, the easier it is to be treated. […] Type 1 grows more slowly than type 2 which is faster growing and more aggressive. If left untreated, papillary RCC may spread. […] Chromophobe RCC tends to be slow growing and less aggressive. Although it can still spread to other parts of the body, this is less likely than in ccRCC and papillary RCC. […] Angiomyolipomas grow very slowly. Their growth is often monitored regularly by imaging scans. The risk of the tumour bursting and bleeding increases with size. […] HOCT is slow growing and is unlikely to spread. There have been rare cases of HOCT spread reported.
  • #29 Kidney cancer | Better Health Channel
    https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/kidney-cancer
    Most people with kidney cancer have no symptoms. […] Signs and symptoms can include: blood in your urine this may be obvious, or the urine may look dark, rusty or brown […] pain in your lower back or side […] a lump in your abdomen […] constant tiredness […] unexplained weight loss […] fever (not caused by a cold or flu). […] In most cases, the earlier that kidney cancer is diagnosed, the better the chance of successful treatment. […] The stage of a cancer means how large it is, where it is, and whether it has spread beyond the kidney. […] Stages 1 and 2 are considered early kidney cancer (only the kidneys are affected). […] Stages 3 and 4 are considered advanced kidney cancer (the cancer has spread beyond the kidneys). […] The grade of the cancer means how quickly a cancer might grow.
  • #30
    https://www.singhealth.com.sg/patient-care/conditions-treatments/kidney-cancer
    Kidney cancer can be successfully treated especially when detected early. […] The likelihood of a cure depends on several factors, including the stage of the cancer, how aggressive the cancer is, how far it has spread, and the patients overall health and response to treatment. […] There are usually no signs or symptoms in the early stages of kidney cancer. […] Symptoms may include blood in the urine, an abdominal mass, persistent pain in the lower back or side, loss of appetite, sudden and unexplained weight loss or anaemia. […] While the symptoms may be caused by a number of other reasons, they should not be ignored. […] You should make an appointment with your doctor if you experience any signs or symptoms that worry you. […] The most common type of kidney cancer which occurs in 9 out of 10 kidney cancer cases is renal cell carcinoma (RCC). […] Each of the RCCs is different in how they develop and change over time or how aggressive they are.
  • #31 Kidney Cancer Symptoms You Shouldn’t Ignore | Fox Chase Cancer Center – Philadelphia PA
    https://www.foxchase.org/blog/kidney-cancer-symptoms-you-shouldnt-ignore
    Having these symptoms doesn’t mean that you definitely have kidney cancer. In fact, most of the time they’re caused by other health conditions, such as urinary tract or bladder infections. […] Still, if you experience any of these symptoms, it’s crucial to let your doctor know right away. They can help determine the cause of your symptoms and make sure you get the treatment you need. […] Discovering kidney cancer early is one of the best ways to ensure that treatment is successful. […] People with advanced kidney disease or those who’ve received a kidney transplant may also have a higher chance of developing kidney cancer.
  • #32 Kidney Cancer | Treatment & Symptoms | The University of Kansas Cancer Center
    https://www.kucancercenter.org/cancer/cancer-types/kidney-cancer
    Kidney cancer often causes no symptoms. See your doctor if you have any of these concerns: […] Blood in the urine […] A lump in the abdomen […] A pain in the side that doesn’t go away […] Fever not caused by a cold or flu […] Persistent feeling of fatigue […] Rapid, unexplained weight loss […] Swelling of the legs and ankles. […] The earlier we find these cancers, the better your chances are for successful treatment of kidney cancer. […] Research indicates a link between kidney disease and kidney cancer. People with kidney disease may be at a higher risk for developing kidney cancer. Additionally, kidney cancer survivors can later develop kidney disease.
  • #33 Kidney Cancer – Symptoms, causes, and treatment | National Kidney Foundation
    https://www.kidney.org/kidney-topics/kidney-cancer
    Kidney cancer starts in the kidneys and can lead to tumors. Symptoms may include blood in urine and back pain. […] In the early stages, most people don’t have signs or symptoms. Kidney cancer is usually found by chance during an abdominal (belly) imaging test for other complaints. As the tumor grows, you may have: Blood in the urine, Pain in the lower back, A lump in the lower back or side of the waist, Unexplained weight loss, night sweats, fever, or fatigue. […] Studies show there is a link between kidney cancer and kidney disease. […] Some studies show that people with kidney disease may have a higher risk for kidney cancer due to: Long-term dialysis: Some studies show that people on long-term dialysis have a 5-fold increased risk for kidney cancer. […] Your doctor will diagnose kidney cancer by reviewing your medical history and doing a physical exam, along with blood and urine tests. […] Once kidney cancer is found, your doctor will run tests to find out if the cancer has spread within the kidney or to other parts of the body. This process is called staging. It is important to know the stage before making a treatment plan. The higher the stage, the more serious the cancer.
  • #34 What are the symptoms of kidney cancer? | Cancer Australia
    https://www.canceraustralia.gov.au/cancer-types/kidney-cancer/what-are-symptoms-kidney-cancer
    Kidney cancers often do not cause symptoms in the early stages of the disease, and sometimes cause very few symptoms, even if they have grown extensively or spread elsewhere. […] The most common symptoms of kidney cancer are: blood in the urine, or passing urine frequently or during the night; change in urine colour – dark, rusty or brown; low back pain on one side that is not due to an injury; a lump in the abdomen, side or lower back; appetite loss; rapid, unexplained weight loss; anaemia (low haemoglobin, which can make you feel tired and weak); fatigue; fever not caused by a cold or flu. […] Many conditions can cause these symptoms, not just kidney cancer. If you have any of these symptoms, talk to your doctor. Blood in the urine should never be ignored.
  • #35 What Does Kidney Cancer Pain Feel Like?
    https://www.medicinenet.com/what_is_kidney_cancer_pain_like/article.htm
    A small tumor in the kidney that may be painless and often an accidental finding on sonography. Side and back pains that are not from an injury may also be symptoms of kidney cancer. […] Patients suffering from advanced kidney cancer may usually complain of back pain, which may be described as a dull ache to a sharp stabbing pain below the ribs on the back or one side of the flank. If there is a sudden persistent pain that lasts more than a few days, a doctor visit is recommended to rule out kidney cancer. Side and back pains that are not from an injury may also be symptoms of kidney cancer. Pain is caused by the tumor growing and pushing against nearby organs. It is usually felt on one side only. Larger tumors may cause compression, stretching, or invasion of structures near the kidney, resulting in pain in the flank, abdomen, or back. The mass may be palpable in the abdomen on a physical exam. If the cancer spreads (metastasizes) beyond the kidney, symptoms depend on the organs involved. The other common signs and symptoms of kidney cancer are:
  • #36 Kidney Cancer Basics | Kidney Cancer | CDC
    https://www.cdc.gov/kidney-cancer/about/index.html
    A person with kidney or renal pelvis cancer may or may not have one or more of the symptoms listed here. The same symptoms can also come from other causes. If you have any of these symptoms, talk to your doctor. […] Blood in the urine. […] A lump or swelling in the kidney area or abdomen. […] Lower back pain or pain in the side that doesn’t go away. […] Feeling tired often. […] Fever that keeps coming back. […] Not feeling like eating. […] Losing weight for no reason that you know of. […] Something blocking your bowels. […] A general feeling of poor health.
  • #37 Recognizing Signs of Kidney Cancer
    https://www.rwjbh.org/treatment-care/cancer/types-of-cancer/kidney-cancer/symptoms/
    Kidney cancer symptoms vary from person to person. The signs may include one or more of the following: […] Blood in the urine. Hematuria, or blood in the urine is one of the most common signs of kidney cancer. […] Recurring fever. This common kidney cancer symptom can occur as a result of a tumor causing an infection and releasing pyrogens, which are substances that can produce a fever. […] Loss of appetite. This possible sign of kidney cancer may occur as the result of changes in hormones due to cancer, or due to a tumor spreading to the gastrointestinal (GI) tract which may produce a false feeling of fullness. […] Frequent tiredness or fatigue. While chronic fatigue alone would not suggest cancer, it is a common side effect. This kidney cancer symptom is usually caused by a shortage of red blood cells in a condition known as anemia.