Guzy i torbiele szczęk
Leczenie
Guzy i torbiele szczęk, choć rzadkie, wymagają indywidualnego podejścia terapeutycznego opartego na dokładnej diagnozie histopatologicznej, lokalizacji, rozmiarze i biologicznym zachowaniu zmiany. Podstawą leczenia jest chirurgia, obejmująca metody takie jak enukleacja, marsupializacja, dekompresja, resekcja oraz enukleacja z kiretażem, dobierane w zależności od charakteru i wielkości zmiany. Torbiele zębopochodne, w tym keratotorbiele, wymagają często bardziej agresywnego leczenia ze względu na wysokie ryzyko nawrotów, co może obejmować usunięcie otaczającej kości oraz zastosowanie kriochirurgii lub chemicznej kauteryzacji. Ameloblastoma, mimo łagodnego charakteru, wykazuje tendencję do nawrotów i wymaga szerokiego marginesu chirurgicznego, natomiast guzy olbrzymiokomórkowe mogą być leczone zarówno chirurgicznie, jak i farmakologicznie (np. denosumabem). W przypadku nowotworów złośliwych, takich jak rak płaskonabłonkowy czy kostniakomięsak, konieczne jest leczenie skojarzone obejmujące chirurgię, radioterapię i chemioterapię.
- Leczenie guzów i torbieli szczęk – wprowadzenie
- Metody chirurgicznego leczenia guzów i torbieli szczęk
- Specyficzne podejścia terapeutyczne w zależności od rodzaju zmiany
- Leczenie torbieli zębopochodnych
- Leczenie keratotorbieli zębopochodnych
- Leczenie ameloblastoma
- Leczenie innych typów guzów
- Terapie uzupełniające i alternatywne
- Techniki rekonstrukcyjne i leczenie wspomagające
- Obserwacja i zapobieganie nawrotom
- Indywidualizacja leczenia i podejście interdyscyplinarne
- Zastosowanie nowoczesnych technologii w diagnozie i leczeniu
- Podsumowanie skuteczności różnych metod leczenia
Leczenie guzów i torbieli szczęk – wprowadzenie
Guzy i torbiele szczęk to stosunkowo rzadkie zmiany rozwijające się w kościach szczęk lub tkankach miękkich jamy ustnej i twarzy. Metody leczenia tych zmian zależą od wielu czynników, w tym typu zmiany, stadium jej rozwoju oraz objawów towarzyszących pacjentowi. Dla zapewnienia optymalnych wyników terapeutycznych kluczowe znaczenie ma indywidualne podejście, uwzględniające cele leczenia oraz preferencje pacjenta12.
Leczenie guzów i torbieli szczęk wymaga zazwyczaj interwencji chirurgicznej, choć w niektórych przypadkach może być zastosowana terapia farmakologiczna lub połączenie obu metod. Wybór odpowiedniej strategii terapeutycznej zależy przede wszystkim od diagnozy histopatologicznej, lokalizacji zmiany oraz jej rozmiaru i zachowania biologicznego13.
Metody chirurgicznego leczenia guzów i torbieli szczęk
Leczenie chirurgiczne stanowi podstawę terapii większości guzów i torbieli szczęk. W trakcie zabiegu chirurg usuwa zmianę, co może obejmować również usunięcie okolicznych zębów, tkanek i części kości szczęki. Pobrany materiał jest następnie przesyłany do badania histopatologicznego, które umożliwia postawienie precyzyjnej diagnozy i zaplanowanie dalszego postępowania14.
Enukleacja
Enukleacja (wyłuszczenie) polega na całkowitym usunięciu torbieli lub guza, czasem wraz z częścią otaczającej kości. Jest to najczęściej stosowana metoda w przypadku mniejszych zmian. Zabieg może być wykonywany w znieczuleniu miejscowym jako procedura ambulatoryjna lub w znieczuleniu ogólnym w warunkach szpitalnych, w zależności od rozmiaru i lokalizacji zmiany56.
Marsupializacja
Marsupializacja polega na wycięciu otworu (okna) w ścianie torbieli, aby umożliwić jej opróżnianie i drenaż. Ta technika pomaga zmniejszyć rozmiar torbieli i sprzyja wypełnianiu się ubytku nową tkanką kostną. Marsupializacja jest szczególnie przydatna w przypadku dużych torbieli, których nagłe usunięcie mogłoby prowadzić do osłabienia struktury kości szczęki57.
Dekompresja
Dekompresja to zatwierdzona alternatywa dla cystektomii w leczeniu torbieli szczęk. Celem tej procedury jest zmniejszenie ciśnienia wewnątrz torbieli poprzez ciągły drenaż, co umożliwia dośrodkowy wzrost nowej tkanki kostnej z kostnych ścian torbieli. Główne zalety dekompresji to oszczędzanie tkanek, minimalizacja ryzyka uszkodzenia sąsiednich struktur oraz uniknięcie kosztów hospitalizacji78.
Skuteczność dekompresji koreluje z wynikami histopatologicznymi, metodą utrzymywania otwartej torbieli oraz wiekiem pacjenta. W przypadku keratotorbieli zębopochodnych po dekompresji zdecydowanie zaleca się wykonanie późniejszej enukleacji89.
Resekcja
Resekcja obejmuje całkowite usunięcie torbieli lub guza wraz z częścią szczęki. Zabieg może obejmować również usunięcie otaczających zębów. Ta metoda jest zazwyczaj stosowana w przypadku zmian agresywnych, aby zapewnić całkowite usunięcie nieprawidłowych tkanek i zminimalizować ryzyko nawrotu. Zabieg ten zwykle przeprowadzany jest w znieczuleniu ogólnym w warunkach szpitalnych510.
Enukleacja z kiretażem
Enukleacja z kiretażem polega na usunięciu torbieli wraz z częścią otaczającej kości, która może zawierać pozostałości wyściółki torbieli. Ta technika jest stosowana w celu zmniejszenia ryzyka nawrotu, zwłaszcza w przypadku zmian o bardziej agresywnym charakterze611.
Specyficzne podejścia terapeutyczne w zależności od rodzaju zmiany
Leczenie torbieli zębopochodnych
Torbiele zębopochodne wymagają zazwyczaj chirurgicznego usunięcia. W przypadku torbieli związanych z zatrzymanymi zębami, leczenie obejmuje usunięcie powiązanego zęba, a następnie usunięcie torbieli12. W przypadku torbieli okolicy wierzchołkowej zęba konieczne jest całkowite usunięcie zakażonej tkanki torbieli, w tym nabłonka ściany torbieli, aby zapobiec nawrotom. Ponadto należy przeprowadzić leczenie kanałowe zajętego zęba lub zębów13.
W przypadku dużych torbieli, szczególnie u pacjentów pediatrycznych, może być stosowana dekompresja, a następnie enukleacja. Marsupializacja może być również wykorzystywana jako technika wspomagająca w leczeniu torbieli14.
Leczenie keratotorbieli zębopochodnych
Keratotorbiele zębopochodne (dawniej określane jako guzy keratotorbielnozębopochodne) charakteryzują się wysokim odsetkiem nawrotów, dlatego wymagają bardziej agresywnego leczenia. Usunięcie torbieli z usunięciem otaczającej kości i kriochirurgia (zastosowanie intensywnego zimna) lub chemiczna kauteryzacja kości (roztworem Carnoya) są najczęstszymi formami leczenia1315.
Duże keratotorbiele szczęk są leczone dekompresją połączoną z późniejszą enukleacją. Ponieważ keratotorbiele mają tendencję do tworzenia komór i mniejszych torbieli łączących się z otaczającą kością, istnieje duże ryzyko nawrotu, szczególnie jeśli pierwotne leczenie chirurgiczne nie doprowadziło do całkowitego usunięcia torbieli1316.
Leczenie ameloblastoma
Ameloblastoma to rzadki, łagodny guz kości, który może występować w kości szczęki dolnej lub górnej. Mimo łagodnego charakteru, może zachowywać się agresywnie i ma tendencję do nawrotów po leczeniu. Najbardziej skuteczną i powszechną metodą leczenia ameloblastoma jest chirurgiczne usunięcie guza. Zabieg może być „zachowawczy”, co oznacza próbę zachowania jak największej ilości tkanki w okolicy zmiany, lub „radykalny”, czyli bardziej inwazyjny zabieg wymagający rekonstrukcji okolicy po usunięciu guza1718.
W zależności od lokalizacji, rozmiaru i podtypu ameloblastoma, leczenie chirurgiczne jest odpowiednio dostosowywane. Leczenie chirurgiczne ameloblastoma wymaga „szerokiego marginesu chirurgicznego”, aby osiągnąć skuteczny i adekwatny efekt zabiegu18. W przypadku jednokomorowych ameloblastoma typu światłowego lub wewnątrzświatłowego może być wskazane podejście wewnątrznosowe16.
Leczenie innych typów guzów
Odontoma są leczone poprzez chirurgiczne usunięcie12. W przypadku włókniaków kostniejących leczenie zwykle wymaga chirurgicznego wycięcia, przy czym większe guzy mogą wymagać bardziej inwazyjnej procedury w celu rekonstrukcji zajętej kości19.
Centralne ziarniniaki olbrzymiokomórkowe są prawie zawsze leczone chirurgicznym usunięciem, a leczenie powiększonych CGCG zwykle wymaga dokładnego łyżeczkowania. Szybko rosnące guzy są bardziej podatne na nawroty i czasami mogą wymagać pełnego wycięcia z otaczającą kością1219.
Terapie uzupełniające i alternatywne
Terapie ukierunkowane w leczeniu guzów łagodnych
Obecnie badane są terapie ukierunkowane i nowatorskie metody niechirurgiczne w leczeniu guzów nieoperacyjnych, z celem uniknięcia operacji lub zmniejszenia jej zakresu. Terapie ukierunkowane wykazały zdolność do zmniejszania rozmiaru guza, spowolnienia progresji guza i zmniejszenia bólu kości20.
Najbardziej powszechną metodą leczenia guzów olbrzymiokomórkowych szczęki jest zabieg chirurgiczny, ale zaproponowano również inne terapie medyczne, takie jak kalcytonina, interferon czy iniekcje kortykosteroidów. Denosumab, przeciwciało monoklonalne przeciwko RANKL, które znacznie hamuje aktywność osteoklastów, został zatwierdzony przez amerykańską Agencję ds. Żywności i Leków (FDA) w 2013 roku do leczenia nieoperacyjnych guzów olbrzymiokomórkowych. Denosumab był również stosowany do osiągnięcia ponownego kostnienia tętniakowatej torbieli kostnej oraz do zmniejszenia rozmiaru, liczby i zawartości płynu w torbielach kości twarzy21.
Leczenie guzów złośliwych
W przypadku raka szczęki pacjenci mogą wymagać dodatkowych metod leczenia onkologicznego, w tym radioterapii i/lub chemioterapii. Najlepsze leczenie zależy od typu guza lub torbieli2223.
Rak płaskonabłonkowy wymaga chirurgicznego usunięcia, chemioterapii i radioterapii. Podobnie kostniakomięsak jest leczony chirurgicznym usunięciem, chemioterapią i radioterapią12. Nowotwory złośliwe często wymagają kombinacji chirurgii, radioterapii lub chemioterapii, w zależności od ich typu i lokalizacji24.
Techniki rekonstrukcyjne i leczenie wspomagające
Rekonstrukcja kości szczęki
W przypadkach, gdy konieczne jest usunięcie znacznych fragmentów kości szczęki, przeprowadzana jest rekonstrukcja, mająca na celu przywrócenie funkcji żucia i estetyki twarzy. W przypadku marginalnej mandibulektomii/alweolektomii, przeszczep kości, zwykle pochodzący z biodra lub boku szczęki, może być zakotwiczony w celu utrzymania grubości szczęki18.
Dla ubytków większych niż 4 cm i tych obejmujących tkanki miękkie, tj. gdy guz naciekł dno jamy ustnej, złotym standardem jest wolny transfer tkanek18. W przypadku zabiegów rekonstrukcyjnych często wykorzystuje się również zaawansowane techniki, takie jak przeszczepy kostne i mikrochirurgia naczyniowa25.
Terapie regeneracyjne
Po usunięciu dużych lub złożonych torbieli, stosuje się terapie regeneracyjne, w tym fibrynę bogatopłytkową i komórki mezenchymalne, aby wspierać proces gojenia i odbudowy tkanek. Fibryna bogatopłytkowa (PRF) i komórki macierzyste mezenchymalne są wykorzystywane w celu skrócenia czasu rekonwalescencji i poprawy ogólnych wyników leczenia2627.
Opieka wspomagająca
Poza leczeniem chirurgicznym i farmakologicznym, pacjenci mogą wymagać dodatkowej opieki wspomagającej, mającej na celu utrzymanie odpowiedniej jakości życia. Obejmuje ona pomoc w odżywianiu, mowie i połykaniu, a także uzupełnienie brakujących zębów2829.
Dla pacjentów po rozległych zabiegach rekonstrukcyjnych kluczowe znaczenie ma szczegółowa opieka pooperacyjna, w tym kontrola bólu, zapobieganie infekcjom i wczesna rehabilitacja funkcjonalna. Czas powrotu do normalnej aktywności zależy od indywidualnych uwarunkowań pacjenta oraz zakresu przeprowadzonego zabiegu30.
Obserwacja i zapobieganie nawrotom
Długoterminowa obserwacja po leczeniu jest kluczowa dla wczesnego wykrycia ewentualnych nawrotów guzów i torbieli szczęk. Identyfikacja nawrotu na wczesnym etapie jest istotna, aby można było zastosować odpowiednie leczenie13.
Zarówno łagodne, jak i złośliwe zmiany mogą nawracać, dlatego regularne wizyty kontrolne są niezbędne dla monitorowania stanu pacjenta. Niektóre typy torbieli, takie jak keratotorbiele zębopochodne, mają wyższe ryzyko nawrotu i wymagają bardziej intensywnego monitorowania2315.
W przypadku niektórych guzów, takich jak ameloblastoma, agresywne leczenie chirurgiczne zazwyczaj zmniejsza szansę nawrotu. Jednak ryzyko nawrotu zależy od typu zmiany, rozmiaru, lokalizacji oraz zastosowanej metody leczenia2.
Indywidualizacja leczenia i podejście interdyscyplinarne
Leczenie guzów i torbieli szczęk wymaga indywidualnego podejścia, uwzględniającego specyfikę każdego przypadku. Czynniki takie jak wiek pacjenta, jego ogólny stan zdrowia, rodzaj zmiany oraz jej lokalizacja i rozmiar mają kluczowe znaczenie dla wyboru optymalnej strategii terapeutycznej131.
Interdyscyplinarne podejście, angażujące specjalistów z różnych dziedzin medycyny, jest często niezbędne dla zapewnienia kompleksowej opieki. W przypadku złożonych przypadków, takich jak rozległe guzy wymagające rekonstrukcji lub zmiany złośliwe wymagające leczenia onkologicznego, współpraca między chirurgami szczękowo-twarzowymi, onkologami, radioterapeutami i innymi specjalistami jest kluczowa dla osiągnięcia optymalnych wyników leczenia32.
Zastosowanie nowoczesnych technologii w diagnozie i leczeniu
Nowoczesne technologie odgrywają coraz większą rolę w diagnostyce i leczeniu guzów i torbieli szczęk. Zaawansowane techniki obrazowania, takie jak tomografia komputerowa i rezonans magnetyczny, umożliwiają precyzyjne określenie rozmiaru, lokalizacji i charakteru zmiany, co jest kluczowe dla zaplanowania odpowiedniego leczenia3033.
Wirtualne planowanie zabiegów chirurgicznych pozwala na symulację różnych technik operacyjnych i wybór optymalnego podejścia, minimalizującego ryzyko powikłań i maksymalizującego skuteczność leczenia. Dzięki temu możliwe jest zaplanowanie zarówno usunięcia zmiany, jak i ewentualnej rekonstrukcji, jeszcze przed przystąpieniem do właściwego zabiegu34.
Ponadto, rozwój sztucznej inteligencji i uczenia maszynowego otwiera nowe możliwości w zakresie automatycznej diagnozy i klasyfikacji zmian na podstawie obrazów radiologicznych, co może przyczynić się do wcześniejszego wykrywania i bardziej precyzyjnego planowania leczenia guzów i torbieli szczęk3536.
Podsumowanie skuteczności różnych metod leczenia
Skuteczność leczenia guzów i torbieli szczęk zależy od wielu czynników, w tym rodzaju zmiany, jej rozmiaru, lokalizacji oraz zastosowanej metody leczenia. W większości przypadków leczenie chirurgiczne pozwala na całkowite wyleczenie, jednak niektóre typy zmian, takie jak keratotorbiele zębopochodne czy ameloblastoma, mają tendencję do nawrotów i mogą wymagać bardziej agresywnego podejścia222.
Metody takie jak enukleacja z kiretażem czy resekcja z odpowiednim marginesem tkanek zdrowych wykazują najniższy odsetek nawrotów, jednak mogą wiązać się z większym ryzykiem powikłań i gorszymi efektami funkcjonalnymi i estetycznymi. Z kolei metody mniej inwazyjne, takie jak dekompresja czy marsupializacja, choć wiążą się z potencjalnie wyższym ryzykiem nawrotu, mogą być preferowane w przypadkach, gdy zachowanie funkcji i estetyki ma kluczowe znaczenie14.
Badania wskazują, że w przypadku większości torbieli szczęk, enukleacja jest rekomendowana jako pierwsza opcja leczenia ze względu na prostotę zabiegu, minimalną inwazyjność, krótki czas leczenia i niewielki wpływ na wygląd i funkcję pacjenta. Resekcja kości, choć charakteryzuje się najniższym odsetkiem nawrotów, może powodować deformację twarzy i pogorszenie funkcji jamy ustnej, dlatego powinna być zarezerwowana dla leczenia dużych wielokomorowych zmian torbielowatych z rozległą erozją kości korowej lub nawracających zmian torbielowatych14.
Niezależnie od wybranej metody leczenia, kluczowe znaczenie ma długoterminowa obserwacja pacjenta, umożliwiająca wczesne wykrycie i leczenie ewentualnych nawrotów13.
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Materiały źródłowe
- #1 Jaw tumors and cysts – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/jaw-tumors-cysts/diagnosis-treatment/drc-20446670
To gather more information about your jaw tumor or cyst, your health care provider may recommend tests prior to treatment. […] Your health care provider uses this information to put together a treatment plan that’s best for you and the most effective option for treating your tumor or cyst. […] Treatment options for jaw tumors and cysts vary, depending on the type of lesion you have, the lesion’s stage of growth and your symptoms. Your treatment team also considers your treatment goals and your personal preferences when making a treatment recommendation. […] Treatment of jaw tumors and cysts generally involves surgical care. In some cases, treatment may be medical therapy or a combination of surgery and medical therapy. […] During surgery, your surgeon removes your jaw tumor or cyst, which may include removing nearby teeth, tissue and jawbone, and sends it to the lab for examination. A pathologist examines the removed tissue and reports a diagnosis during the procedure so that the surgeon can act on this information immediately. […] Other treatments may include: […] Long-term follow-up exams after treatment can address any recurrence of jaw tumors and cysts. Identifying recurrence early is important so they can be treated appropriately.
- #2 Jaw tumors and cysts – Symptoms and causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/jaw-tumors-cysts/symptoms-causes/syc-20350973
Jaw tumors and cysts are relatively rare growths or lesions that develop in the jawbone or the soft tissues in the mouth and face. […] Treatment options for jaw tumors and cysts vary, depending on the type of growth or lesion you have, the stage of growth, and your symptoms. Mouth, jaw and face (oral and maxillofacial) surgeons can treat your jaw tumor or cyst usually by surgery, or in some cases, by medical therapy or a combination of surgery and medical therapy. […] Although this tumor can recur after treatment, aggressive surgical treatment will typically reduce the chance of recurrence. […] One type of these tumors can grow rapidly, cause pain and destroy bone, and has a tendency to recur after surgical treatment. […] Typically these tumors require surgical treatment. […] Although this cyst is typically slow growing, it can still be destructive to the jaw and teeth if left untreated over a long period of time. […] However, the chances of tumor recurrence are typically lessened by more-aggressive forms of surgical treatment. […] If you are diagnosed with or suspected of having a jaw tumor or cyst, your primary care provider can refer you to a specialist for diagnosis and treatment.
- #3 Jaw tumors and cysts | Health Library | Memorial Health Systemhttps://www.mhsystem.org/health-library/con-20155324/
Treatment options for jaw tumors and cysts vary, depending on the type of growth or lesion you have, the stage of growth, and your symptoms. […] Treatment of jaw tumors and cysts generally involves surgical care. In some cases, treatment may be medical therapy or a combination of surgery and medical therapy. […] During surgery, your surgeon removes your jaw tumor or cyst, which may include removing nearby teeth, tissue and jawbone, and sends it to the lab for examination. […] Other treatments may include: medical therapy for certain types of jaw tumors and cysts. […] Long-term follow-up exams after treatment can address any recurrence of jaw tumors and cysts. Identifying recurrence early is important so they can be treated appropriately.
- #4https://www.kuh.ku.edu.tr/mayo-clinic-care-network/mayo-clinic-health-information-library/diseases-conditions/jaw-tumors-and-cysts
Jaw tumors and cysts are relatively rare growths or lesions that develop in the jawbone or the soft tissues in the mouth and face. […] Treatment options for jaw tumors and cysts vary, depending on the type of growth or lesion you have, the stage of growth, and your symptoms. Mouth, jaw and face (oral and maxillofacial) surgeons can treat your jaw tumor or cyst usually by surgery, or in some cases, by medical therapy or a combination of surgery and medical therapy. […] Treatment of jaw tumors and cysts generally involves surgical care. In some cases, treatment may be medical therapy or a combination of surgery and medical therapy. […] During surgery, your surgeon removes your jaw tumor or cyst, which may include removing nearby teeth, tissue and jawbone, and sends it to the lab for examination. A pathologist examines the removed tissue and reports a diagnosis during the procedure so that the surgeon can act on this information immediately.
- #5 Nuface – Cyst and Tumor of Jaw and Facehttps://cleftsurgerymumbai.in/cyst-and-tumour-of-jaw
Excision involves complete removal of the cyst or tumor, sometimes with removal of some of the surrounding bone. This may be done under local anesthesia as office base procedure or under general anaesthesia in hospital set up depending on the size and location of cyst or tumor. […] Marsupialization involves cutting out a hole (a window) in the wall of the cyst so that it will stay open and drain. A drain may be placed to direct the fluid from the cyst to flow into the mouth. The only portion of the cyst that is removed is the piece to make the window. This process helps shrink the cyst and fill in the bone in your jaw. […] Resection involves complete removal of the cyst or tumor along with a portion of your jaw. Some of the surrounding teeth may also be removed. This is typically done with aggressive lesions to ensure that the abnormal tissues are completely removed. This procedure usually takes place at Hospital under general anesthesia.
- #6 Cysts of the jaws – Wikipediahttps://en.wikipedia.org/wiki/Cysts_of_the_jaws
Cysts treatment is limited to surgical removal for the majority of cysts. There are two techniques used to manage cysts with the deciding factor being the size of the cyst. […] Enucleation removal of the entire cyst. A mucoperiosteal flap is raised overlying the cyst and the entire cyst subsequently removed. The defect is completely closed by the placement of sutures to realign the margins of the flap. […] Marsupialization the creation of a window into the wall of a cyst by raising a mucoperiosteal flap and attaching the cyst lining to the oral mucosa – allowing the contents to be drained. […] Enucleation following marsupialization marsupialization is carried out as a single procedure, but usually it is followed by a second procedure (enucleation) to remove the cyst. […] Enucleation with curettage this is the removal of the cyst and some of the surrounding bone, which may contain remnants of the lining of the cyst.
- #7 The effectiveness of decompression as initial treatment for jaw cysts: A 10-year retrospective studyhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6344015/
Decompression is an approved alternative to cystectomy in the treatment of jaw cysts. This study aimed to evaluate its effectiveness as an initial procedure, as well as factors with potential to influence outcome. […] Treatments range from single decompression, marsupialization, enucleation and bone resection to a combination of these approaches. […] Decompression as initial procedure is a common conservative approach requiring preparation and preservation of a cyst opening. The aim is to decrease intracystic pressure by constant drainage, so allowing new centripetal bone growth from the bony cyst walls. […] The main advantages of decompression are that it spares tissue, minimizes the likelihood of damage to adjacent structures, and avoids the cost of hospitalization. […] Some authors have suggested subsequent enucleation for aggressive cysts with a high relapse rate, and when the outcome of decompression is unsatisfactory.
- #8 The effectiveness of decompression as initial treatment for jaw cysts: A 10-year retrospective studyhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6344015/
Decompression could be performed as a procedure completed in one session or combined with subsequent enucleation, mainly dependent on histopathological findings. Subsequent enucleation of odontogenic keratocysts is highly recommended. […] The effectiveness of decompression was found to correlate with histopathology, the means of keeping the cyst open, and patients age. […] Decompression is mainly performed to avoid morbidity. It can be performed as a single complete procedure or combined with subsequent enucleation, mainly depending on histopathological findings. Enucleation after decompression is highly recommended for odontogenic keratocysts.
- #9 Decompression: a first-intention treatment for âlargeâ non-syndromic odontogenic keratocysts | Journal of Oral Medicine and Oral SurgeryMendeleyhttps://www.jomos.org/articles/mbcb/full_html/2021/02/mbcb200121/mbcb200121.html
Decompression aims to decrease the volume of the lesion of âlargeâ OKCs, in order to prevent surgery-related fractures and to preserve the surrounding important anatomical structures such as the inferior alveolar nerve. […] Nowadays, minimally invasive surgery prevails. And since OKC was returned into the odontogenic cysts group in the WHO classification, decompression should be considered as the first intention treatment. […] Decompression reduces cystic lumen and thickens the epithelial wall, thus facilitating enucleation. […] Decompression therefore appears as a first-choice therapeutic option for large keratocysts. […] For a âlargeâ OKC, decompression should first be undertaken, followed if necessary by an enucleation. […] Decompression, with a drain or by marsupialization, may lead to OKC complete disappearance of the lesion.
- #10 Cysts & Tumors of the Jaw | Rockcliff Oral Surgeryhttps://rockclifforalsurgery.com/specialties/cysts-tumors-of-the-jaw
Excision involves complete removal of the cyst or tumor, sometimes with removal of some of the surrounding bone. […] Resection involves complete removal of the cyst or tumor along with a portion of your jaw. Some of the surrounding teeth may also be removed. This is typically done with aggressive lesions to ensure that the abnormal tissues are completely removed. […] Many patients are able to go home after their procedure. Depending on the type of surgery you have, you will likely be able to go back to work or school after 1-2 weeks. While you are healing you will need to avoid any strenuous physical activity. […] Depending on your procedure, you may be limited to a very soft, no-chew diet.
- #11 Benign Tumors & Cysts Treatment in Chicago In Northwest Indiana | OMHNAhttps://omhna.com/services/benign-tumors-and-cysts/
Benign tumors of the head and neck may involve any part of the face, neck, or jaws and vary in etiology. Many of these tumors will require a needle aspiration or a biopsy to confirm the diagnosis, although some may be diagnosed on imaging. Treatment varies depending on the histology and location. Our OMHNA surgeons have completed extensive fellowship training in the field of head and neck oncology and microvascular reconstruction, and are well versed in the treatment of head and neck tumors and tumors of the jaws. […] Depending on the type of benign tumor involved, treatment may vary from enucleation and curettage (or scraping out the tumor) to removing a section of the jaw bone. Similarly treatment options for odontogenic cysts of the jaws also depend on the histology or type. Our OMHNA surgeons will discuss with you your different treatment options so that you can make the best choice that suits your needs.
- #12 Tumors and Cysts of the Jaw: Symptoms, Causes, Treatment, and Morehttps://www.healthline.com/health/cancer/tumors-on-jaw
Surgical removal is the main treatment for many types of jaw tumors and cysts. Depending on the location and extent of your tumor or cyst, you may also need to have teeth removed or receive reconstruction of your jawbone. […] Treatment for dentigerous cysts involves extraction of the associated tooth followed by removal of the cyst. […] Odontomas are treated with surgical removal. […] Ameloblastoma is usually surgically removed, and jaw reconstruction surgery may be necessary; radiation therapy is considered if surgery isn’t an option. […] Ameloblastic carcinoma requires surgical removal, and may also involve radiation therapy, cryotherapy, or chemotherapy. […] Central giant cell granulomas are almost always cured with surgical removal. […] Squamous cell carcinoma treatment includes surgical removal, chemotherapy, and radiation therapy. […] Osteosarcoma is treated with surgical removal, chemotherapy, and radiation therapy.
- #13 Nuface – Cyst and Tumor of Jaw and Facehttps://cleftsurgerymumbai.in/cyst-and-tumour-of-jaw
Depending on the size location of the cyst, as well as, taking into account your general health and your previous experiences of having dental treatment local or general anesthesia maybe administered. […] The infected tissue of the periapical cyst must be entirely removed, including the epithelium of the cyst wall; otherwise, a relapse is likely to occur. Root canal treatment should be performed on the affected tooth/teeth. […] Removal of the cyst with removal of surrounding bone and cryosurgery (intense cold is applied to the cyst and bone) or chemical cauterisation of bone (with Carnoys solution) are the most common forms of treatment. […] The odontogenic keratocyst has a number of 'compartments’ and has connecting smaller cysts that extend into the surrounding bone. Because of this, there is frequent tendency for the condition to recur, particularly if the original surgical treatment did not result in complete removal of the cyst.
- #14https://journals.lww.com/cmj/fulltext/2024/05050/epidemiological_analysis_of_the_clinicopathologic.16.aspx
Jaw cysts can be categorized as either a single cystic lesion (only one compartment) or a multiple cystic lesion (multiple compartments). […] Most jaw cysts were enucleated. In pediatric patients with DCs or large cysts, decompression was performed. Large jaw OKCs were treated with decompression combined with subsequent enucleation. Bone resection was performed for large multilocular cystic lesions with extensive erosion of the cortical bone or repeated recurrent cystic lesions. […] All the patients with jaw cysts had surgical treatment, including enucleation, decompression, resection, or a combination of these. […] Treatment of jaw cysts remains controversial. In our study, we compared the different surgical treatment procedures for treating jaw cysts in relation to the recurrence rate. Recurrence was found in 32 of 2103 cases (1.52%) of primary cystic lesions. There was no statistically significant difference between the groups treated by enucleation, decompression, decompression and second-stage enucleation, and resection. Therefore, cyst enucleation is recommended as the first choice of treatment for jaw cysts owing to its simplicity of surgery, minimal invasiveness, short treatment duration, and low impact on patients appearance and function. Bone resection was the treatment with the lowest recurrence rate. However, radical resection can cause facial deformity and poor oral function, and should be reserved for the treatment of large multilocular cystic lesions with extensive erosion of the cortical bone or repeated recurrent cystic lesions. […] In conclusion, our results showed that the OKC is the most frequent type of jaw cyst based on a large series sample in West China. Enucleation is recommended as the first choice for the treatment of jaw cysts.
- #15 Cysts of the jaws – Wikipediahttps://en.wikipedia.org/wiki/Cysts_of_the_jaws
The exception to these treatments; is the management of cysts which have a higher rate of recurrence for example odontogenic keratocysts. Options to reduce the recurrence rate include: curettage post enucleation, Carnoy’s solution (treatment of the cavity with a potent fixative) or mandibular resection. These treatments are less conservative than the above options.
- #16 Endonasal Endoscopic Resection of Odontogenic Cysts and Tumors with Maxillary Destructionhttp://clinmedjournals.org/articles/iaoms/research-reports-in-oral-and-maxillofacial-surgery-rroms-7-067.php?jid=iaoms
Keratocysts have a greater possibility of recurrence, so complete resection of the cyst with a peripheral bone sector is advisable. […] The usual treatment of ameloblastoma is complete surgical resection with free margins by partial or total maxillectomy with reconstruction. […] Endonasal surgery may be indicated in selected patients with unicystic ameloblastomas of the luminal or intraluminal type. […] The endonasal approach with endoscopes through a wide medial maxillary antrostomy, combined with a prelacrimal approach or anterior maxillary sinusotomy was very effective to expose adequately and completely remove odontogenic cysts and tumors.
- #17 Ameloblastoma | Bone Cancer Research Trusthttps://www.bcrt.org.uk/information/information-by-type/ameloblastoma/
Ameloblastoma is a rare, benign, tumour of the bone which can occur in the lower or upper jaw bone. […] It is important that this non-cancerous tumour is diagnosed early in order to prevent its excessive growth, bone destruction and invasion into soft tissues surrounding the jaw and possible progression to a cancerous tumour. […] Although there is currently no identifiable cause for ameloblastoma, there are risk factors that are thought to increase the likelihood of an individual developing this tumour type. […] Diagnosis of a suspected ameloblastoma usually follows a clinical examination, X-rays and an incisional biopsy under a local anaesthetic. […] The most effective and common treatment method for ameloblastoma is the surgical removal of the tumour. Surgery can either be âconservativeâ, which attempts to retain as much tissue as possible in the area, or surgery may be âradicalâ, a more invasive procedure which requires reconstruction of the area following tumour removal.
- #18 Ameloblastoma | Bone Cancer Research Trusthttps://www.bcrt.org.uk/information/information-by-type/ameloblastoma/
Depending upon the location, size and the subtype of ameloblastoma the surgical treatment is tailored accordingly. […] The surgical treatment of ameloblastomas requires a âwide surgical marginâ in order to achieve effective and adequate surgery. […] For marginal mandibulectomy/alveolectomy, a bone graft which is usually sourced from the hip or the side of the jaw can be anchored to keep the thickness of the jaw. […] For defects more than 4cm and those involving soft tissue i.e. the tumour has invaded the floor of mouth, free tissue transfer is the gold standard. […] Ultimately, it is highly beneficial to diagnose and treat ameloblastomas as early as possible. Early diagnosis and adequate treatment leads to an excellent outlook for patients in previously reported ameloblastoma cases.
- #19 Nuface – Cyst and Tumor of Jaw and Facehttps://cleftsurgerymumbai.in/cyst-and-tumour-of-jaw
Treatment for ossifying fibroma usually requires surgical excision where the oral surgeon will remove the tumor completely from the tissue. Larger tumors might require a more invasive procedure to reconstruct the affected bone. […] The treatment for enlarged CGCG is usually thorough curettage. Recurrence ranges from 15%20%, second curettage is sufficient to prevent further recurrence. Rapidly growing tumours are more likely to recur and can sometimes require full excision with surrounding bone.
- #20 Current concepts in targeted therapies for benign tumors of the jaw – a review of the literaturehttps://pmc.ncbi.nlm.nih.gov/articles/PMC11538012/
Benign odontogenic and maxillofacial bone tumors often require radical surgery with consequent morbidity that impacts post-surgical quality of life of patients. […] Currently, targeted therapies and novel non-surgical therapeutics are being explored for management of non-resectable tumors with the aim of avoiding surgery or minimizing surgical scope. […] Targeted therapies decreased tumor size, slowed down tumor progression and diminished bone pains. Surgery is still the gold standard but targeted therapies are promising adjuvant or alternative treatment options to reduce tumor progression and morbidity of tumor surgery. […] Based on current advancements in molecular therapeutics, targeted therapies and novel non-surgical therapeutics are being explored for management of non-resectable tumors with the aim of avoiding surgery or decreasing the extent of surgery.
- #21 Current concepts in targeted therapies for benign tumors of the jaw – a review of the literaturehttps://pmc.ncbi.nlm.nih.gov/articles/PMC11538012/
The most common treatment for giant cell tumors of the jaw is surgery but other medical therapies like calcitonin, interferon, corticosteroid injections have been proposed. […] Denosumab, a monoclonal antibody against RANKL that substantially suppresses osteoclast activity has been approved by the United States Food and Drug Administration (FDA) since 2013 for treatment of non-resectable giant cell tumors. […] Denosumab has been used to achieve re-ossification of the aneurysmal bone cyst and to decrease cystic size, number and fluid contents in facial bones. […] Imatinib is a tyrosine kinase inhibitor most commonly used to target the BCR-ABL tyrosine kinase in pediatric patients with Philadelphia chromosome positive chronic myelogenous leukemia or acute lymphoblastic lymphoma. […] This review has some limitations. First, it reported clinical outcomes in case reports, case series and descriptive studies. […] In summary, targeted therapies may pave the way for a paradigm shift in the management of benign tumors of the jaw. However, a multicenter randomised controlled clinical trial is still warranted.
- #22 Jaw Cysts & Tumors: Symptoms, Types & Removalhttps://my.clevelandclinic.org/health/diseases/jaw-cysts-tumors
Cysts and tumors can form in and around your jaw. Most growths are benign (noncancerous). Rarely, theyre a form of jaw cancer. […] The most common treatment is surgery. […] Most people need surgery to remove the cyst or tumor. In addition to removing the growth, your surgeon may also remove any affected tissue. This includes damaged teeth or parts of your lower or upper jaw. Surgery to remove segments of the lower part of your jaw is called a mandibulectomy. Surgery that removes all or part of your upper jaw is called maxillectomy. […] If you have jaw cancer, your healthcare provider may also recommend cancer treatments, including radiation therapy and/or chemotherapy. The best treatment for you depends on the type of tumor or cyst. […] Surgery can cure most jaw cysts and tumors. Depending on the type, you may need follow-up visits to monitor new growths.
- #23 Jaw Cancer: Symptoms, Causes & Treatmenthttps://my.clevelandclinic.org/health/diseases/jaw-cancer
Jaw cancer includes various tumors that form from the tissue involved in tooth formation (odontogenic tissue). Your prognosis (outcome) depends on the type of tumor and how soon you receive treatment. The most common treatments are surgery and radiation therapy. […] Some types of tumors are curable if you catch them early and your provider removes them with surgery. […] Most people with jaw cancer need surgery to remove the tumor. You may also need surgery to remove affected tissue from or around your jaw. […] Depending on the type of jaw cancer, you may need additional cancer treatments, including: Radiation therapy: Uses a machine that directs high beams of radiation to shrink tumors. […] Most people with mouth tumors both benign and malignant need surgery to remove them. With jaw cancer, you may need additional treatments like radiation to keep tumors from returning.
- #24 Jaw Tumour & Cyst Treatment In London | Harley Street Clinichttps://harleystreetmaxillofacialclinic.com/oral-conditions/jaw-tumours-cysts/
Whether you have a tumour or a minor cyst impacting your jaw and surrounding tissues, you will receive the same exceptional level of care and support. […] For consultations, medical procedures, or surgeries related to jaw tumours and cysts, our highly experienced surgeons provide exceptional care at the clinic. […] Treatment is tailored to each patient based on medical needs and the specific diagnosis of the cyst or tumour. Your consultant will discuss your condition, treatment options, and expected outcomes in detail. […] In some cases, medication may help, but surgery is often the most effective long-term solution. […] Benign growths are typically removed through surgery and may sometimes require bone reconstruction or dental implants. […] Malignant tumours often require a combination of surgery, radiotherapy, or chemotherapy, depending on their type and location.
- #25 Tumors and Cysts of the Mouth and Jaw McLean, Jaw Tumor Washington D.C., Mouth Cyst Northern Virginiahttps://novasurgicare.com/beautiful-smiles/oral-surgery-mclean-va-dc/oral-pathology-virginia/jaw-tumors/
The majority of tumors within the mouth and jaw are benign. Still, malignant tumor growth does occur and even benign tumors are painful to cope with. Regardless of whether your tumor is benign or malignant, itâs important to seek removal to better your oral health, lifestyle, and address any oral cancer concerns. […] Dentists often discover these premalignant tumors during routine, oral cancer screenings and refer the patients to a specialist like Dr. Hamrah. […] If you live in Northern Virginia or the Greater Washington, D.C. area and require an oral cancer evaluation to determine if you have tumor growth in your mouth or jaw, please contact Dr. Hamrah today at 703-288-4495 to schedule your personal consultation.
- #26 Jaw Tumor Treatment West Palm Beach | Jaw Cancer Treatment in Jupiter, FL | CRJ Institutehttps://www.crjinstitute.com/oral-cancer-and-conditions/benign-and-malignant-cysts-and-tumors-of-the-jaws/
To further enhance healing, regenerative therapies like platelet-rich fibrin (PRF) and mesenchymal stem cells may be utilized, reducing recovery times and improving overall outcomes. […] CRJ Institute is dedicated to delivering patient-focused care, leveraging advanced surgical innovations, and providing a collaborative environment where each patient’s unique needs are thoroughly addressed. […] From initial consultation and precise diagnosis to effective removal and reconstruction, CRJ Institute prioritizes safety, function, and natural-looking results. […] If you or a loved one are experiencing symptoms related to cysts or tumors of the jaw, early intervention can make all the difference. […] Even benign cysts can expand over time, damaging nearby bone or teeth. Early treatment can prevent complications and preserve oral structures.
- #27 Jaw Cyst Treatment West Palm Beach | Jaw Tumor Surgery in West Palm Beach | AQ Surgeryhttps://aqsurgery.com/conditions/jaw-cysts-and-tumors/
In smaller, benign cases, cysts can be removed through enucleation, a simple surgical procedure with minimal disruption. […] Larger or more complex cysts may require marsupialization or decompression to shrink them before complete removal, preserving critical structures like teeth and nerves. […] For cases requiring extensive tumor or cyst removal, Dr. Quimby incorporates regenerative therapies, including platelet-rich fibrin and mesenchymal stem cells. […] Early intervention helps prevent these issues, ensuring the best possible outcome. […] If cancer is detected, Dr. Quimby may work in collaboration with other specialists, such as oncologists, to develop a comprehensive treatment plan that includes surgery, chemotherapy, or radiation. […] Dr. Quimbys holistic approach focuses on restoring function and aesthetics, ensuring her patients recover and thrive after treatment. […] Whether your condition requires jaw cyst treatment, jaw tumor surgery in West Palm Beach, or ongoing monitoring, you can trust AQ Surgery for expert, compassionate care.
- #28https://www.kuh.ku.edu.tr/mayo-clinic-care-network/mayo-clinic-health-information-library/diseases-conditions/jaw-tumors-and-cysts
Other treatments may include: Reconstruction of the jawbone or other structures, Medical therapy for certain types of jaw tumors and cysts, Supportive care to help maintain your quality of life, including assisting with nutrition, speech and swallowing, and replacements for missing teeth. […] Long-term follow-up exams after treatment can address any recurrence of jaw tumors and cysts. Identifying recurrence early is important so they can be treated appropriately.
- #29 Mayo Clinic Health Library – Jaw tumors and cysts | Swiss Medical Networkhttps://www.swissmedical.net/fr/healtcare-library/con-20155324
Other treatments may include: Reconstruction of the jawbone or other structures, Medical therapy for certain types of jaw tumors and cysts, Supportive care to help maintain your quality of life, including assisting with nutrition, speech and swallowing, and replacements for missing teeth. […] Long-term follow-up exams after treatment can address any recurrence of jaw tumors and cysts. Identifying recurrence early is important so they can be treated appropriately.
- #30 Cyst and Tumor Removal – Rivershttps://riversoralsurgery.com/cyst-and-tumor-removal/
Jaw tumors and cysts that grow in the soft tissue of the mouth or jawbone can vary in size. These growths are usually noncancerous (benign), but they can be aggressive and invade the surrounding bone and tissue and may displace teeth. Treatment options vary with the type of growth or lesion, the state of the growth, and symptoms. Our surgeons perform surgery, or in some cases, use medical therapy or a combination of surgery and medical therapy to eliminate the concern. […] Removing cysts and tumors of the mouth requires a thoughtful plan that prioritizes patient comfort: […] Our team uses comprehensive diagnostic techniques including advanced imaging to determine the best course of action. […] We employ the latest minimally-invasive surgical procedures to make sure that we are both efficient and mindful of patient comfort. Various anesthesia options are available to ensure that you are at ease throughout the procedure. […] Our team will provide detailed care instructions and are available to address any concerns you may have while you recover. Swelling and some pain may occur and often are treated using over-the-counter pain medications.
- #31 Jaw tumors and cysts – Augusta HealthSearchClose SearchSearch IconSearch IconClose Search IconMobile Menu IconMobile Menu Close IconInstagramFacebookTwitterYoutubehttps://www.augustahealth.com/disease/jaw-tumors-and-cysts/
Treatment options for jaw tumors and cysts vary, depending on the type of growth or lesion you have, the stage of growth, and your symptoms. Mouth, jaw and face (oral and maxillofacial) surgeons can treat your jaw tumor or cyst usually by surgery, or in some cases, by medical therapy or a combination of surgery and medical therapy. […] Treatment options for jaw tumors and cysts vary, depending on the type of lesion you have, the lesion’s stage of growth and your symptoms. Your treatment team also considers your treatment goals and your personal preferences when making a treatment recommendation. […] Treatment of jaw tumors and cysts generally involves surgical care. In some cases, treatment may be medical therapy or a combination of surgery and medical therapy. […] During surgery, your surgeon removes your jaw tumor or cyst, which may include removing nearby teeth, tissue and jawbone, and sends it to the lab for examination. A pathologist examines the removed tissue and reports a diagnosis during the procedure so that the surgeon can act on this information immediately. […] Other treatments may include: medical therapy for certain types of jaw tumors and cysts. […] Long-term follow-up exams after treatment can address any recurrence of jaw tumors and cysts. Identifying recurrence early is important so they can be treated appropriately.
- #32 Jaw cancer: Symptoms and treatment | CURAPROXhttps://curaprox.us/blog/post/jaw-cancer-symptoms-and-treatment?srsltid=AfmBOoqeYYAQqiiB8_Ls0VbtugUH99dnUqXCGFjjbcwR_PyvSUy1bFTU
A team of specialists always collaborates to treat jaw cancer, pooling expertise from various medical disciplines. In so-called tumour conferences or tumour boards, experts review each case to devise the most effective treatment plan for the individual. Generally, surgical removal of the tumour is the standard course of action. Depending on the location, size and stage of the tumour, treatment plans often include radiotherapy or chemotherapy, either before or after surgery. […] The primary objectives of jaw cancer treatment are: To remove the tumour completely, To preserve or restore jaw function and facial appearance as effectively as possible, To prevent recurrence of the tumour. […] Depending on the size and location of the tumour, surgery for jaw cancer can be very complex. With small tumours, preservation of the jawbone is feasible. With larger tumours, parts of the jawbone often need to be excised completely to ensure that the entire tumour is removed.
- #33 Jaw Tumor Treatment West Palm Beach | Jaw Cancer Treatment in Jupiter, FL | CRJ Institutehttps://www.crjinstitute.com/oral-cancer-and-conditions/benign-and-malignant-cysts-and-tumors-of-the-jaws/
Our team uses cutting-edge imaging technologies like 3D scans and virtual surgery planning to accurately assess each case. […] At CRJ Institute, jaw cysts are addressed through our Comprehensive Reconstruction of the Jaw (CRJ) procedure. […] By removing the cyst and simultaneously reconstructing the affected area, Dr. Anastasiya Quimby and her team preserve key structures like teeth and nerves, ensuring both comfort and stability. […] At CRJ Institute, our providers manage jaw tumors through personalized CRJ procedures. […] Drawing on Dr. Quimby’s specialized training in head and neck oncology and microvascular reconstruction, we remove the tumor while reconstructing the affected area to restore both function and appearance. […] When significant portions of the jawbone must be removed or when cysts/tumors have caused extensive damage, reconstruction plays a vital role in restoring both appearance and function.
- #34 Jaw Cyst Treatment West Palm Beach | Jaw Tumor Surgery in West Palm Beach | AQ Surgeryhttps://aqsurgery.com/conditions/jaw-cysts-and-tumors/
Jaw cysts and tumors can be concerning for patients experiencing swelling, discomfort, or difficulty chewing. […] Dr. Anastasiya Quimby provides comprehensive jaw tumor surgery and jaw cyst treatment in West Palm Beach. […] By focusing on both the removal of cysts and tumors and the reconstruction of affected areas, she helps her patients regain function and confidence in their appearance. […] Dr. Quimby uses advanced diagnostic tools to accurately assess jaw cysts and tumors. […] Early and accurate diagnosis is essential for developing a personalized treatment plan. […] Jaw tumor surgery in West Palm Beach varies based on the size, location, and whether the condition is benign or malignant. […] Dr. Quimby uses advanced tools like 3D imaging and virtual surgery planning to precisely map out each surgery, ensuring effective removal and preservation of surrounding structures.
- #35 Deep learning based diagnosis for cysts and tumors of jaw with massive healthy samples | Scientific Reportshttps://www.nature.com/articles/s41598-022-05913-5
We aimed to develop an explainable and reliable method to diagnose cysts and tumors of the jaw with massive panoramic radiographs of healthy peoples based on deep learning […] The proposed method showed encouraging performance in the diagnosis of cysts and tumors of the jaw. The classified categories and segmented lesion areas serve as the diagnostic basis for further diagnosis, which provides a reliable tool for diagnosing jaw tumors and cysts. […] The treatment modalities for different types of cysts and tumors are different. Keratocystic odontogenic tumors (KCOTs), like other cystic lesions, are usually enucleated without radical jaw segmentation. Ameloblastomas (ABs), on the other hand, require more radical surgical removal than KCOTs, which drastically affects patients lives, causing facial deformity and subsequent social and emotional incompetence.
- #36 Deep learning based diagnosis for cysts and tumors of jaw with massive healthy samples | Scientific Reportshttps://www.nature.com/articles/s41598-022-05913-5
The proposed method can simultaneously predict the lesion category and area, increasing the reliability and explainability of the predicted results. […] The segmentation results can be served as reliable references for further diagnosis. It provides an effective tool for diagnosing cysts and tumors of the jaw.