Guzy i torbiele szczęk – Rokowania, prognozy i postęp choroby

Guzy i torbiele szczęk
Rokowania, prognozy i postęp choroby

Guzy i torbiele szczęk, choć stosunkowo rzadkie, wykazują zróżnicowane rokowanie zależne od typu zmiany, jej wielkości, stadium oraz zastosowanego leczenia. Większość z nich to zmiany łagodne, takie jak torbiele okołowierzchołkowe, zawiązkowe czy zębopochodne, które po leczeniu chirurgicznym cechują się niskim ryzykiem nawrotów i dobrym rokowaniem. Wyjątkiem są rogowaciejące torbiele zębopochodne (KCOT) oraz niektóre guzy, np. ameloblastoma i śluzak zębopochodny, które wykazują wyższą tendencję do nawrotów (10-72%). W rzadkich przypadkach występują zmiany złośliwe, takie jak rak płaskonabłonkowy, mięsak kościopochodny czy rak ameloblastyczny, z 5-letnimi wskaźnikami przeżycia odpowiednio na poziomie 84,5%, 73,6% i 69,1%, co wymaga agresywnego i kompleksowego leczenia. Wielkość zmiany oraz brak przerzutów do węzłów chłonnych są istotnymi czynnikami prognostycznymi.

Guzy i torbiele szczęk: Rokowanie (przewidywanie wyników)

Ogólne czynniki wpływające na rokowanie
Rokowanie dla poszczególnych typów zmian
Wpływ metod diagnostycznych na rokowanie
Leczenie a rokowanie
Zalecenia dla pacjentów
Podsumowanie rokowania
Kolejne rozdziały

Guzy i torbiele szczęk: Rokowanie (przewidywanie wyników)

Guzy i torbiele szczęk stanowią stosunkowo rzadkie zmiany patologiczne rozwijające się w kości szczęki lub w tkankach miękkich jamy ustnej i twarzy. Rokowanie w przypadku tych patologii jest zróżnicowane i zależy od wielu czynników, takich jak typ zmiany, stadium wzrostu oraz zastosowane leczenie.¹²

Ogólne czynniki wpływające na rokowanie

Czynniki związane z lepszym rokowaniem w przypadku guzów i torbieli szczęk obejmują:³

Młodszy wiek pacjenta
Możliwość chirurgicznego usunięcia zmiany
Mniejszy rozmiar guza
Brak przerzutów do węzłów chłonnych lub odległych narządów

Wielkość zmiany ma istotne znaczenie prognostyczne – większe torbiele wiążą się z wyższym ryzykiem powikłań po leczeniu.⁴ Warto zaznaczyć, że większość guzów i torbieli szczęk to zmiany łagodne (nienowotworowe), co oznacza, że choć mogą rosnąć i wpływać na tkanki twarzy i jamy ustnej, zwykle nie rozprzestrzeniają się do innych części ciała.⁵

Rokowanie dla poszczególnych typów zmian

Wyniki leczenia i ryzyko nawrotu znacząco różnią się w zależności od rodzaju zmiany:⁶⁷

Torbiele odontogenne

Torbiele okołowierzchołkowe (periapical cysts) – zwykle nie nawracają po leczeniu chirurgicznym, co daje doskonałe rokowanie długoterminowe.⁸
Torbiele zawiązkowe (dentigerous cysts) – charakteryzują się doskonałym rokowaniem przy prawidłowym leczeniu i niskim odsetkiem nawrotów.⁹ Chociaż zwykle rozwijają się powoli, mogą niszczyć kość i zęby, jeśli pozostawić je bez leczenia przez dłuższy czas.¹⁰
Rogowaciejące torbiele zębopochodne (odontogenic keratocysts) – mają tendencję do nawrotów po leczeniu chirurgicznym. Są one czasem związane z zespołami genetycznymi, takimi jak zespół nabłoniaków znamionowych (zespół Gorlina-Goltza), który powoduje rozwój mnogich rogowaciejących torbieli zębopochodnych w szczękach, mnogich raków podstawnokomórkowych skóry i innych charakterystycznych cech.¹¹

⁸⁹¹⁰

Guzy odontogenne

Zębiaki (odontomas) – mają dobre rokowanie po leczeniu chirurgicznym, bez nawrotów odnotowanych nawet przez 20 lat po zabiegu.¹²¹³
Ameloblastoma – charakteryzuje się wskaźnikiem nawrotów wynoszącym około 10-20% przypadków. Agresywne leczenie chirurgiczne zwykle zmniejsza szansę nawrotu.¹⁴¹⁵
Śluzak zębopochodny (odontogenic myxoma) – znany jest z nawrotów po leczeniu chirurgicznym, jednak szanse nawrotu guza są zazwyczaj mniejsze przy bardziej agresywnych formach leczenia chirurgicznego.¹⁶
Ziarniniak olbrzymiokomórkowy centralny (central giant cell granuloma) – może być poważnie deformujący, a wskaźnik nawrotów waha się między 11% a 72%.¹⁷

¹⁴¹⁵¹⁷

Zmiany złośliwe

W rzadkich przypadkach guzy lub torbiele szczęk mogą być złośliwe (nowotworowe). Lekarze określają je wtedy jako raka szczęki. Bez leczenia złośliwe torbiele i guzy szczęk mogą rozprzestrzeniać się na części ciała inne niż szczęka.¹⁸

Rak płaskonabłonkowy (squamous cell carcinoma) – ma wysokie ryzyko nawrotu, co wiąże się z gorszym rokowaniem. Badanie z 2019 roku wykazało 5-letni wskaźnik przeżycia bez choroby na poziomie 84,5% w przypadku leczenia wyłącznie chirurgicznego.¹⁹
Mięsak kościopochodny (osteosarcoma) – według niewielkiego badania z 2019 roku 5-letni wskaźnik przeżycia bez nawrotu wynosi 73,6%.²⁰
Rak ameloblastyczny (ameloblastic carcinoma) – 5-letni wskaźnik przeżycia wynosi około 69,1%.²¹

¹⁹²⁰²¹

Wpływ metod diagnostycznych na rokowanie

Dokładna diagnostyka ma kluczowe znaczenie dla ustalenia właściwego rokowania i planu leczenia. Tradycyjne metody obrazowania, takie jak radiografia panoramiczna, są cennym narzędziem, jednak ich interpretacja może stanowić wyzwanie, szczególnie w przypadku zmian o podobnych cechach radiologicznych, takich jak KCOT i ameloblastoma.²²

W ostatnich latach rozwijane są zaawansowane metody diagnostyczne oparte na głębokim uczeniu (deep learning), które wykazują obiecujące wyniki w diagnostyce guzów i torbieli szczęk. Metody te mogą jednocześnie przewidywać kategorię i obszar zmiany, zwiększając wiarygodność i możliwość wyjaśnienia wyników diagnostycznych, co przekłada się na dokładniejsze prognozowanie przebiegu choroby.²³²⁴

Metody oparte na sieciach konwolucyjnych (CNN) wykazują wysoką czułość, swoistość, dokładność i pole pod krzywą ROC (AUC) w automatycznym diagnozowaniu torbieli i guzów zębopochodnych w obu szczękach na zdjęciach panoramicznych, nawet przy ograniczonej liczbie dostępnych obrazów.²⁵ Takie podejście może przyczynić się do wcześniejszego wykrywania zmian i poprawy rokowania.²⁶

Leczenie a rokowanie

Operacja jest najczęstszą metodą leczenia guzów i torbieli szczęk. Większość pacjentów wymaga zabiegu chirurgicznego w celu usunięcia zmiany. Oprócz usunięcia samego guza, chirurg może również usunąć dotknięte tkanki, w tym uszkodzone zęby lub części górnej lub dolnej szczęki.²⁷

Leczenie chirurgiczne może wyleczyć większość torbieli i guzów szczęk. W zależności od typu zmiany, pacjenci mogą wymagać wizyt kontrolnych w celu monitorowania pod kątem nowych zmian.²⁸ Długoterminowe badania kontrolne po leczeniu mogą pomóc w wykryciu nawrotu guzów i torbieli szczęk. Wczesne zidentyfikowanie nawrotu jest ważne, aby zmiany mogły być odpowiednio leczone.²⁹

Warto zaznaczyć, że dodatkowe procedury podczas zabiegu chirurgicznego mogą zmniejszać ryzyko powikłań wynikających z wyłuszczenia torbieli szczęki, z wyjątkiem przeszczepów kości. W przypadku wykonywania przeszczepów kostnych należy rozważyć możliwość drugiego zabiegu i podjąć dokładne środki ostrożności, aby zapobiec infekcjom.³⁰

Zalecenia dla pacjentów

Pacjenci z rozpoznanymi guzami lub torbielami szczęk powinni być:³¹³²

Poinformowani z wyprzedzeniem o ryzyku nawrotu i możliwych powikłaniach
Umówieni na regularne wizyty kontrolne
Poddani dodatkowemu leczeniu w razie potrzeby

³¹

Jeśli zdiagnozowano u pacjenta guz lub torbiel szczęki lub podejrzewa się ich obecność, lekarz podstawowej opieki zdrowotnej może skierować go do specjalisty w celu diagnostyki i leczenia.³² Plan leczenia opracowany przez specjalistę powinien być dostosowany do indywidualnych potrzeb pacjenta i stanowić najbardziej skuteczną opcję leczenia guza lub torbieli.³³

Podsumowanie rokowania

Rokowanie w przypadku guzów i torbieli szczęk jest generalnie dobre, szczególnie w przypadku zmian łagodnych, które są odpowiednio leczone chirurgicznie. Jednak niektóre typy zmian, takie jak ameloblastoma, śluzak zębopochodny, rogowaciejące torbiele zębopochodne czy ziarniniak olbrzymiokomórkowy centralny, mają znaczącą tendencję do nawrotów, co wymaga ścisłego monitorowania po leczeniu.³⁴³⁵

Zmiany złośliwe szczęk, choć rzadkie, wiążą się z gorszym rokowaniem i wymagają kompleksowego podejścia terapeutycznego. Postępy w diagnostyce obrazowej i metodach opartych na sztucznej inteligencji przyczyniają się do wcześniejszego wykrywania zmian i dokładniejszego prognozowania, co może poprawić wyniki leczenia.³⁶³⁷

Kolejne rozdziały

Zapraszamy do dalszego czytania naszego leksykonu.

Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.

Materiały źródłowe

#1 Jaw tumors and cysts – Symptoms and causes – Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/jaw-tumors-cysts/symptoms-causes/syc-20350973
Jaw tumors and cysts are relatively rare growths or lesions that develop in the jawbone or the soft tissues in the mouth and face. […] Treatment options for jaw tumors and cysts vary, depending on the type of growth or lesion you have, the stage of growth, and your symptoms. […] Although this tumor can recur after treatment, aggressive surgical treatment will typically reduce the chance of recurrence. […] One type of these tumors can grow rapidly, cause pain and destroy bone, and has a tendency to recur after surgical treatment. […] Typically these tumors require surgical treatment. […] Although this cyst is typically slow growing, it can still be destructive to the jaw and teeth if left untreated over a long period of time. […] Odontogenic myxomas are known to recur after surgical treatment; however, the chances of tumor recurrence are typically lessened by more-aggressive forms of surgical treatment.
#2 Jaw Cysts & Tumors: Symptoms, Types & Removal
https://my.clevelandclinic.org/health/diseases/jaw-cysts-tumors
Jaw cysts and tumors are growths that can form from bone (including teeth) and soft tissue in your mouth. A jaw cyst is a sac of fluid or semi-liquid material. A jaw tumor is a solid mass that forms when abnormal cells clump together. Both growths are usually benign (noncancerous). This means that, although they may grow and impact tissue in your face and mouth, they usually don’t spread to other parts of your body. […] In rare instances, jaw cysts or tumors are malignant (cancerous). Healthcare providers refer to them as jaw cancer. Without treatment, malignant jaw cysts and tumors can spread to body parts other than your jaw. […] Most people need surgery to remove the cyst or tumor. In addition to removing the growth, your surgeon may also remove any affected tissue. This includes damaged teeth or parts of your lower or upper jaw.
#3 Tumors and Cysts of the Jaw: Symptoms, Causes, Treatment, and More
https://www.healthline.com/health/cancer/tumors-on-jaw
Most cysts or tumors that develop in your jaw have a good outlook if treated properly, but some can be aggressive and cause problems. […] The outlook for jaw tumors and cysts varies widely depending on what type you have. In general, factors associated with a better outlook include: younger age, able to be removed surgically, smaller tumor, spread to lymph nodes or distant body parts. […] Dentigerous cysts have an excellent outlook if treated properly with a low recurrence rate. […] Odontomas generally have a good outlook if treated surgically with no reoccurrence reported for up to 20 years. […] Ameloblastoma has a recurrence rate in about 10% to 20% of cases. […] Ameloblastic carcinoma has a 5-year survival rate reported as 69.1%. […] Central giant cell granulomas can be severely deforming with a recurrence rate between 11% and 72%. […] Squamous cell carcinoma has a high risk of recurrence, which is associated with a poor outlook. A 2019 study reported a 5-year disease-free survival rate of 84.5% when treated with surgery alone. […] Osteosarcoma has a small 2019 study reporting a 5-year recurrence-free survival rate of 73.6%.
#4 Predicting Risk Factors for Complications in Jaw Cyst Treatment: Insights from a Retrospective Study
https://www.jkaoms.org/view.html?uid=3516&vmd=Full
Within the limitations of our study, additional procedures reduced the risk of complications resulting from jaw cyst enucleation, except for bone grafts. […] Large cyst size was associated with a higher risk of complications. […] It is important to consider the possibility of a second procedure and take thorough precautions to prevent infections when performing bone grafts. […] Patients should be informed of these risks in advance, scheduled for regular follow-up, and provided additional treatment when necessary.
#5 Jaw Cysts & Tumors: Symptoms, Types & Removal
https://my.clevelandclinic.org/health/diseases/jaw-cysts-tumors
Jaw cysts and tumors are growths that can form from bone (including teeth) and soft tissue in your mouth. A jaw cyst is a sac of fluid or semi-liquid material. A jaw tumor is a solid mass that forms when abnormal cells clump together. Both growths are usually benign (noncancerous). This means that, although they may grow and impact tissue in your face and mouth, they usually don’t spread to other parts of your body. […] In rare instances, jaw cysts or tumors are malignant (cancerous). Healthcare providers refer to them as jaw cancer. Without treatment, malignant jaw cysts and tumors can spread to body parts other than your jaw. […] Most people need surgery to remove the cyst or tumor. In addition to removing the growth, your surgeon may also remove any affected tissue. This includes damaged teeth or parts of your lower or upper jaw.
#6 Jaw Cysts & Tumors: Symptoms, Types & Removal
https://my.clevelandclinic.org/health/diseases/jaw-cysts-tumors
Surgery can cure most jaw cysts and tumors. Depending on the type, you may need follow-up visits to monitor new growths. […] For example, periapical cysts, odontomas and dentigerous cysts don’t usually grow back (recur) after surgery. But central giant cell granuloma, odontogenic myxoma and odontogenic keratocysts often do. Ameloblastoma recurs in up to 20% of people.
#7 Tumors and Cysts of the Jaw: Symptoms, Causes, Treatment, and More
https://www.healthline.com/health/cancer/tumors-on-jaw
Most cysts or tumors that develop in your jaw have a good outlook if treated properly, but some can be aggressive and cause problems. […] The outlook for jaw tumors and cysts varies widely depending on what type you have. In general, factors associated with a better outlook include: younger age, able to be removed surgically, smaller tumor, spread to lymph nodes or distant body parts. […] Dentigerous cysts have an excellent outlook if treated properly with a low recurrence rate. […] Odontomas generally have a good outlook if treated surgically with no reoccurrence reported for up to 20 years. […] Ameloblastoma has a recurrence rate in about 10% to 20% of cases. […] Ameloblastic carcinoma has a 5-year survival rate reported as 69.1%. […] Central giant cell granulomas can be severely deforming with a recurrence rate between 11% and 72%. […] Squamous cell carcinoma has a high risk of recurrence, which is associated with a poor outlook. A 2019 study reported a 5-year disease-free survival rate of 84.5% when treated with surgery alone. […] Osteosarcoma has a small 2019 study reporting a 5-year recurrence-free survival rate of 73.6%.
#8 Jaw Cysts & Tumors: Symptoms, Types & Removal
https://my.clevelandclinic.org/health/diseases/jaw-cysts-tumors
Surgery can cure most jaw cysts and tumors. Depending on the type, you may need follow-up visits to monitor new growths. […] For example, periapical cysts, odontomas and dentigerous cysts don’t usually grow back (recur) after surgery. But central giant cell granuloma, odontogenic myxoma and odontogenic keratocysts often do. Ameloblastoma recurs in up to 20% of people.
#9 Tumors and Cysts of the Jaw: Symptoms, Causes, Treatment, and More
https://www.healthline.com/health/cancer/tumors-on-jaw
Most cysts or tumors that develop in your jaw have a good outlook if treated properly, but some can be aggressive and cause problems. […] The outlook for jaw tumors and cysts varies widely depending on what type you have. In general, factors associated with a better outlook include: younger age, able to be removed surgically, smaller tumor, spread to lymph nodes or distant body parts. […] Dentigerous cysts have an excellent outlook if treated properly with a low recurrence rate. […] Odontomas generally have a good outlook if treated surgically with no reoccurrence reported for up to 20 years. […] Ameloblastoma has a recurrence rate in about 10% to 20% of cases. […] Ameloblastic carcinoma has a 5-year survival rate reported as 69.1%. […] Central giant cell granulomas can be severely deforming with a recurrence rate between 11% and 72%. […] Squamous cell carcinoma has a high risk of recurrence, which is associated with a poor outlook. A 2019 study reported a 5-year disease-free survival rate of 84.5% when treated with surgery alone. […] Osteosarcoma has a small 2019 study reporting a 5-year recurrence-free survival rate of 73.6%.
#10 Jaw tumors and cysts – Symptoms and causes – Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/jaw-tumors-cysts/symptoms-causes/syc-20350973
Jaw tumors and cysts are relatively rare growths or lesions that develop in the jawbone or the soft tissues in the mouth and face. […] Treatment options for jaw tumors and cysts vary, depending on the type of growth or lesion you have, the stage of growth, and your symptoms. […] Although this tumor can recur after treatment, aggressive surgical treatment will typically reduce the chance of recurrence. […] One type of these tumors can grow rapidly, cause pain and destroy bone, and has a tendency to recur after surgical treatment. […] Typically these tumors require surgical treatment. […] Although this cyst is typically slow growing, it can still be destructive to the jaw and teeth if left untreated over a long period of time. […] Odontogenic myxomas are known to recur after surgical treatment; however, the chances of tumor recurrence are typically lessened by more-aggressive forms of surgical treatment.
#11 Jaw tumors and cysts – Symptoms and causes – Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/jaw-tumors-cysts/symptoms-causes/syc-20350973
If you are diagnosed with or suspected of having a jaw tumor or cyst, your primary care provider can refer you to a specialist for diagnosis and treatment. […] Generally, the cause of jaw tumors and cysts is not known; however, some are associated with gene changes (mutations) or genetic syndromes. […] This syndrome results in the development of multiple odontogenic keratocysts within the jaws, multiple basal cell skin cancers and other characteristics.
#12 Jaw Cysts & Tumors: Symptoms, Types & Removal
https://my.clevelandclinic.org/health/diseases/jaw-cysts-tumors
Surgery can cure most jaw cysts and tumors. Depending on the type, you may need follow-up visits to monitor new growths. […] For example, periapical cysts, odontomas and dentigerous cysts don’t usually grow back (recur) after surgery. But central giant cell granuloma, odontogenic myxoma and odontogenic keratocysts often do. Ameloblastoma recurs in up to 20% of people.
#13 Tumors and Cysts of the Jaw: Symptoms, Causes, Treatment, and More
https://www.healthline.com/health/cancer/tumors-on-jaw
Most cysts or tumors that develop in your jaw have a good outlook if treated properly, but some can be aggressive and cause problems. […] The outlook for jaw tumors and cysts varies widely depending on what type you have. In general, factors associated with a better outlook include: younger age, able to be removed surgically, smaller tumor, spread to lymph nodes or distant body parts. […] Dentigerous cysts have an excellent outlook if treated properly with a low recurrence rate. […] Odontomas generally have a good outlook if treated surgically with no reoccurrence reported for up to 20 years. […] Ameloblastoma has a recurrence rate in about 10% to 20% of cases. […] Ameloblastic carcinoma has a 5-year survival rate reported as 69.1%. […] Central giant cell granulomas can be severely deforming with a recurrence rate between 11% and 72%. […] Squamous cell carcinoma has a high risk of recurrence, which is associated with a poor outlook. A 2019 study reported a 5-year disease-free survival rate of 84.5% when treated with surgery alone. […] Osteosarcoma has a small 2019 study reporting a 5-year recurrence-free survival rate of 73.6%.
#14 Jaw tumors and cysts – Symptoms and causes – Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/jaw-tumors-cysts/symptoms-causes/syc-20350973
Jaw tumors and cysts are relatively rare growths or lesions that develop in the jawbone or the soft tissues in the mouth and face. […] Treatment options for jaw tumors and cysts vary, depending on the type of growth or lesion you have, the stage of growth, and your symptoms. […] Although this tumor can recur after treatment, aggressive surgical treatment will typically reduce the chance of recurrence. […] One type of these tumors can grow rapidly, cause pain and destroy bone, and has a tendency to recur after surgical treatment. […] Typically these tumors require surgical treatment. […] Although this cyst is typically slow growing, it can still be destructive to the jaw and teeth if left untreated over a long period of time. […] Odontogenic myxomas are known to recur after surgical treatment; however, the chances of tumor recurrence are typically lessened by more-aggressive forms of surgical treatment.
#15 Tumors and Cysts of the Jaw: Symptoms, Causes, Treatment, and More
https://www.healthline.com/health/cancer/tumors-on-jaw
Most cysts or tumors that develop in your jaw have a good outlook if treated properly, but some can be aggressive and cause problems. […] The outlook for jaw tumors and cysts varies widely depending on what type you have. In general, factors associated with a better outlook include: younger age, able to be removed surgically, smaller tumor, spread to lymph nodes or distant body parts. […] Dentigerous cysts have an excellent outlook if treated properly with a low recurrence rate. […] Odontomas generally have a good outlook if treated surgically with no reoccurrence reported for up to 20 years. […] Ameloblastoma has a recurrence rate in about 10% to 20% of cases. […] Ameloblastic carcinoma has a 5-year survival rate reported as 69.1%. […] Central giant cell granulomas can be severely deforming with a recurrence rate between 11% and 72%. […] Squamous cell carcinoma has a high risk of recurrence, which is associated with a poor outlook. A 2019 study reported a 5-year disease-free survival rate of 84.5% when treated with surgery alone. […] Osteosarcoma has a small 2019 study reporting a 5-year recurrence-free survival rate of 73.6%.
#16 Jaw tumors and cysts – Symptoms and causes – Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/jaw-tumors-cysts/symptoms-causes/syc-20350973
Jaw tumors and cysts are relatively rare growths or lesions that develop in the jawbone or the soft tissues in the mouth and face. […] Treatment options for jaw tumors and cysts vary, depending on the type of growth or lesion you have, the stage of growth, and your symptoms. […] Although this tumor can recur after treatment, aggressive surgical treatment will typically reduce the chance of recurrence. […] One type of these tumors can grow rapidly, cause pain and destroy bone, and has a tendency to recur after surgical treatment. […] Typically these tumors require surgical treatment. […] Although this cyst is typically slow growing, it can still be destructive to the jaw and teeth if left untreated over a long period of time. […] Odontogenic myxomas are known to recur after surgical treatment; however, the chances of tumor recurrence are typically lessened by more-aggressive forms of surgical treatment.
#17 Tumors and Cysts of the Jaw: Symptoms, Causes, Treatment, and More
https://www.healthline.com/health/cancer/tumors-on-jaw
Most cysts or tumors that develop in your jaw have a good outlook if treated properly, but some can be aggressive and cause problems. […] The outlook for jaw tumors and cysts varies widely depending on what type you have. In general, factors associated with a better outlook include: younger age, able to be removed surgically, smaller tumor, spread to lymph nodes or distant body parts. […] Dentigerous cysts have an excellent outlook if treated properly with a low recurrence rate. […] Odontomas generally have a good outlook if treated surgically with no reoccurrence reported for up to 20 years. […] Ameloblastoma has a recurrence rate in about 10% to 20% of cases. […] Ameloblastic carcinoma has a 5-year survival rate reported as 69.1%. […] Central giant cell granulomas can be severely deforming with a recurrence rate between 11% and 72%. […] Squamous cell carcinoma has a high risk of recurrence, which is associated with a poor outlook. A 2019 study reported a 5-year disease-free survival rate of 84.5% when treated with surgery alone. […] Osteosarcoma has a small 2019 study reporting a 5-year recurrence-free survival rate of 73.6%.
#18 Jaw Cysts & Tumors: Symptoms, Types & Removal
https://my.clevelandclinic.org/health/diseases/jaw-cysts-tumors
Jaw cysts and tumors are growths that can form from bone (including teeth) and soft tissue in your mouth. A jaw cyst is a sac of fluid or semi-liquid material. A jaw tumor is a solid mass that forms when abnormal cells clump together. Both growths are usually benign (noncancerous). This means that, although they may grow and impact tissue in your face and mouth, they usually don’t spread to other parts of your body. […] In rare instances, jaw cysts or tumors are malignant (cancerous). Healthcare providers refer to them as jaw cancer. Without treatment, malignant jaw cysts and tumors can spread to body parts other than your jaw. […] Most people need surgery to remove the cyst or tumor. In addition to removing the growth, your surgeon may also remove any affected tissue. This includes damaged teeth or parts of your lower or upper jaw.
#19 Tumors and Cysts of the Jaw: Symptoms, Causes, Treatment, and More
https://www.healthline.com/health/cancer/tumors-on-jaw
Most cysts or tumors that develop in your jaw have a good outlook if treated properly, but some can be aggressive and cause problems. […] The outlook for jaw tumors and cysts varies widely depending on what type you have. In general, factors associated with a better outlook include: younger age, able to be removed surgically, smaller tumor, spread to lymph nodes or distant body parts. […] Dentigerous cysts have an excellent outlook if treated properly with a low recurrence rate. […] Odontomas generally have a good outlook if treated surgically with no reoccurrence reported for up to 20 years. […] Ameloblastoma has a recurrence rate in about 10% to 20% of cases. […] Ameloblastic carcinoma has a 5-year survival rate reported as 69.1%. […] Central giant cell granulomas can be severely deforming with a recurrence rate between 11% and 72%. […] Squamous cell carcinoma has a high risk of recurrence, which is associated with a poor outlook. A 2019 study reported a 5-year disease-free survival rate of 84.5% when treated with surgery alone. […] Osteosarcoma has a small 2019 study reporting a 5-year recurrence-free survival rate of 73.6%.
#20 Tumors and Cysts of the Jaw: Symptoms, Causes, Treatment, and More
https://www.healthline.com/health/cancer/tumors-on-jaw
Most cysts or tumors that develop in your jaw have a good outlook if treated properly, but some can be aggressive and cause problems. […] The outlook for jaw tumors and cysts varies widely depending on what type you have. In general, factors associated with a better outlook include: younger age, able to be removed surgically, smaller tumor, spread to lymph nodes or distant body parts. […] Dentigerous cysts have an excellent outlook if treated properly with a low recurrence rate. […] Odontomas generally have a good outlook if treated surgically with no reoccurrence reported for up to 20 years. […] Ameloblastoma has a recurrence rate in about 10% to 20% of cases. […] Ameloblastic carcinoma has a 5-year survival rate reported as 69.1%. […] Central giant cell granulomas can be severely deforming with a recurrence rate between 11% and 72%. […] Squamous cell carcinoma has a high risk of recurrence, which is associated with a poor outlook. A 2019 study reported a 5-year disease-free survival rate of 84.5% when treated with surgery alone. […] Osteosarcoma has a small 2019 study reporting a 5-year recurrence-free survival rate of 73.6%.
#21 Tumors and Cysts of the Jaw: Symptoms, Causes, Treatment, and More
https://www.healthline.com/health/cancer/tumors-on-jaw
Most cysts or tumors that develop in your jaw have a good outlook if treated properly, but some can be aggressive and cause problems. […] The outlook for jaw tumors and cysts varies widely depending on what type you have. In general, factors associated with a better outlook include: younger age, able to be removed surgically, smaller tumor, spread to lymph nodes or distant body parts. […] Dentigerous cysts have an excellent outlook if treated properly with a low recurrence rate. […] Odontomas generally have a good outlook if treated surgically with no reoccurrence reported for up to 20 years. […] Ameloblastoma has a recurrence rate in about 10% to 20% of cases. […] Ameloblastic carcinoma has a 5-year survival rate reported as 69.1%. […] Central giant cell granulomas can be severely deforming with a recurrence rate between 11% and 72%. […] Squamous cell carcinoma has a high risk of recurrence, which is associated with a poor outlook. A 2019 study reported a 5-year disease-free survival rate of 84.5% when treated with surgery alone. […] Osteosarcoma has a small 2019 study reporting a 5-year recurrence-free survival rate of 73.6%.
#22 Deep learning based diagnosis for cysts and tumors of jaw with massive healthy samples
https://pmc.ncbi.nlm.nih.gov/articles/PMC8814152/
We aimed to develop an explainable and reliable method to diagnose cysts and tumors of the jaw with massive panoramic radiographs of healthy peoples based on deep learning, since collecting and labeling massive lesion samples are time-consuming, and existing deep learning-based methods lack explainability. […] The proposed method showed encouraging performance in the diagnosis of cysts and tumors of the jaw. The classified categories and segmented lesion areas serve as the diagnostic basis for further diagnosis, which provides a reliable tool for diagnosing jaw tumors and cysts. […] Accurate diagnosis of different types of cysts and tumors is a challenging task. Some cysts and tumors have very similar radiological characteristics. […] The main differentiating feature in diagnosing KCOT from ABs is the significant anteroposterior extension of the unilocular radiolucent lesion in the posterior mandible marrow space.
#23 Deep learning based diagnosis for cysts and tumors of jaw with massive healthy samples | Scientific Reports
https://www.nature.com/articles/s41598-022-05913-5
We aimed to develop an explainable and reliable method to diagnose cysts and tumors of the jaw with massive panoramic radiographs of healthy peoples based on deep learning, since collecting and labeling massive lesion samples are time-consuming, and existing deep learning-based methods lack explainability. […] The proposed method showed encouraging performance in the diagnosis of cysts and tumors of the jaw. The classified categories and segmented lesion areas serve as the diagnostic basis for further diagnosis, which provides a reliable tool for diagnosing jaw tumors and cysts. […] Accurate diagnosis of different types of cysts and tumors is a challenging task. […] The proposed method can simultaneously predict the lesion category and area, increasing the reliability and explainability of the predicted results.
#24 Automatic diagnosis for cysts and tumors of both jaws on panoramic radiographs using a deep convolution neural network
https://pmc.ncbi.nlm.nih.gov/articles/PMC7719862/
The purpose of this study was to automatically diagnose odontogenic cysts and tumors of both jaws on panoramic radiographs using deep learning. […] The CNN method we developed for automatically diagnosing odontogenic cysts and tumors of both jaws on panoramic radiographs using data augmentation showed high sensitivity, specificity, accuracy, and AUC despite the limited number of panoramic images involved. […] The deep CNN method we developed for automatically diagnosing odontogenic cysts and tumors in both jaws on panoramic radiographs showed high sensitivity, specificity, accuracy, and AUC when using augmented data, despite the limited number of panoramic images available.
#25 Automatic diagnosis for cysts and tumors of both jaws on panoramic radiographs using a deep convolution neural network
https://pmc.ncbi.nlm.nih.gov/articles/PMC7719862/
The purpose of this study was to automatically diagnose odontogenic cysts and tumors of both jaws on panoramic radiographs using deep learning. […] The CNN method we developed for automatically diagnosing odontogenic cysts and tumors of both jaws on panoramic radiographs using data augmentation showed high sensitivity, specificity, accuracy, and AUC despite the limited number of panoramic images involved. […] The deep CNN method we developed for automatically diagnosing odontogenic cysts and tumors in both jaws on panoramic radiographs showed high sensitivity, specificity, accuracy, and AUC when using augmented data, despite the limited number of panoramic images available.
#26 Deep learning based diagnosis for cysts and tumors of jaw with massive healthy samples | Scientific Reports
https://www.nature.com/articles/s41598-022-05913-5
The segmentation sub-branch will predict the lesion area, which can serve as the diagnosis reference for dentists and oral surgeons to diagnose the jaw tumors and cysts further. […] The proposed method can achieve promising diagnosis performance with massive healthy samples. […] The segmentation results can be served as reliable references for further diagnosis. It provides an effective tool for diagnosing cysts and tumors of the jaw.
#27 Jaw Cysts & Tumors: Symptoms, Types & Removal
https://my.clevelandclinic.org/health/diseases/jaw-cysts-tumors
Jaw cysts and tumors are growths that can form from bone (including teeth) and soft tissue in your mouth. A jaw cyst is a sac of fluid or semi-liquid material. A jaw tumor is a solid mass that forms when abnormal cells clump together. Both growths are usually benign (noncancerous). This means that, although they may grow and impact tissue in your face and mouth, they usually don’t spread to other parts of your body. […] In rare instances, jaw cysts or tumors are malignant (cancerous). Healthcare providers refer to them as jaw cancer. Without treatment, malignant jaw cysts and tumors can spread to body parts other than your jaw. […] Most people need surgery to remove the cyst or tumor. In addition to removing the growth, your surgeon may also remove any affected tissue. This includes damaged teeth or parts of your lower or upper jaw.
#28 Jaw Cysts & Tumors: Symptoms, Types & Removal
https://my.clevelandclinic.org/health/diseases/jaw-cysts-tumors
Surgery can cure most jaw cysts and tumors. Depending on the type, you may need follow-up visits to monitor new growths. […] For example, periapical cysts, odontomas and dentigerous cysts don’t usually grow back (recur) after surgery. But central giant cell granuloma, odontogenic myxoma and odontogenic keratocysts often do. Ameloblastoma recurs in up to 20% of people.
#29 Jaw tumors and cysts – Diagnosis and treatment – Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/jaw-tumors-cysts/diagnosis-treatment/drc-20446670
To gather more information about your jaw tumor or cyst, your health care provider may recommend tests prior to treatment. […] Your health care provider uses this information to put together a treatment plan that’s best for you and the most effective option for treating your tumor or cyst. […] Treatment options for jaw tumors and cysts vary, depending on the type of lesion you have, the lesion’s stage of growth and your symptoms. […] Long-term follow-up exams after treatment can address any recurrence of jaw tumors and cysts. Identifying recurrence early is important so they can be treated appropriately.
#30 Predicting Risk Factors for Complications in Jaw Cyst Treatment: Insights from a Retrospective Study
https://www.jkaoms.org/view.html?uid=3516&vmd=Full
Within the limitations of our study, additional procedures reduced the risk of complications resulting from jaw cyst enucleation, except for bone grafts. […] Large cyst size was associated with a higher risk of complications. […] It is important to consider the possibility of a second procedure and take thorough precautions to prevent infections when performing bone grafts. […] Patients should be informed of these risks in advance, scheduled for regular follow-up, and provided additional treatment when necessary.
#31 Predicting Risk Factors for Complications in Jaw Cyst Treatment: Insights from a Retrospective Study
https://www.jkaoms.org/view.html?uid=3516&vmd=Full
Within the limitations of our study, additional procedures reduced the risk of complications resulting from jaw cyst enucleation, except for bone grafts. […] Large cyst size was associated with a higher risk of complications. […] It is important to consider the possibility of a second procedure and take thorough precautions to prevent infections when performing bone grafts. […] Patients should be informed of these risks in advance, scheduled for regular follow-up, and provided additional treatment when necessary.
#32 Jaw tumors and cysts – Symptoms and causes – Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/jaw-tumors-cysts/symptoms-causes/syc-20350973
If you are diagnosed with or suspected of having a jaw tumor or cyst, your primary care provider can refer you to a specialist for diagnosis and treatment. […] Generally, the cause of jaw tumors and cysts is not known; however, some are associated with gene changes (mutations) or genetic syndromes. […] This syndrome results in the development of multiple odontogenic keratocysts within the jaws, multiple basal cell skin cancers and other characteristics.
#33 Jaw tumors and cysts – Diagnosis and treatment – Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/jaw-tumors-cysts/diagnosis-treatment/drc-20446670
To gather more information about your jaw tumor or cyst, your health care provider may recommend tests prior to treatment. […] Your health care provider uses this information to put together a treatment plan that’s best for you and the most effective option for treating your tumor or cyst. […] Treatment options for jaw tumors and cysts vary, depending on the type of lesion you have, the lesion’s stage of growth and your symptoms. […] Long-term follow-up exams after treatment can address any recurrence of jaw tumors and cysts. Identifying recurrence early is important so they can be treated appropriately.
#34 Tumors and Cysts of the Jaw: Symptoms, Causes, Treatment, and More
https://www.healthline.com/health/cancer/tumors-on-jaw
Most cysts or tumors that develop in your jaw have a good outlook if treated properly, but some can be aggressive and cause problems. […] The outlook for jaw tumors and cysts varies widely depending on what type you have. In general, factors associated with a better outlook include: younger age, able to be removed surgically, smaller tumor, spread to lymph nodes or distant body parts. […] Dentigerous cysts have an excellent outlook if treated properly with a low recurrence rate. […] Odontomas generally have a good outlook if treated surgically with no reoccurrence reported for up to 20 years. […] Ameloblastoma has a recurrence rate in about 10% to 20% of cases. […] Ameloblastic carcinoma has a 5-year survival rate reported as 69.1%. […] Central giant cell granulomas can be severely deforming with a recurrence rate between 11% and 72%. […] Squamous cell carcinoma has a high risk of recurrence, which is associated with a poor outlook. A 2019 study reported a 5-year disease-free survival rate of 84.5% when treated with surgery alone. […] Osteosarcoma has a small 2019 study reporting a 5-year recurrence-free survival rate of 73.6%.
#35 Jaw Cysts & Tumors: Symptoms, Types & Removal
https://my.clevelandclinic.org/health/diseases/jaw-cysts-tumors
Surgery can cure most jaw cysts and tumors. Depending on the type, you may need follow-up visits to monitor new growths. […] For example, periapical cysts, odontomas and dentigerous cysts don’t usually grow back (recur) after surgery. But central giant cell granuloma, odontogenic myxoma and odontogenic keratocysts often do. Ameloblastoma recurs in up to 20% of people.
#36 Deep learning based diagnosis for cysts and tumors of jaw with massive healthy samples | Scientific Reports
https://www.nature.com/articles/s41598-022-05913-5
We aimed to develop an explainable and reliable method to diagnose cysts and tumors of the jaw with massive panoramic radiographs of healthy peoples based on deep learning, since collecting and labeling massive lesion samples are time-consuming, and existing deep learning-based methods lack explainability. […] The proposed method showed encouraging performance in the diagnosis of cysts and tumors of the jaw. The classified categories and segmented lesion areas serve as the diagnostic basis for further diagnosis, which provides a reliable tool for diagnosing jaw tumors and cysts. […] Accurate diagnosis of different types of cysts and tumors is a challenging task. […] The proposed method can simultaneously predict the lesion category and area, increasing the reliability and explainability of the predicted results.
#37 Automatic diagnosis for cysts and tumors of both jaws on panoramic radiographs using a deep convolution neural network
https://pmc.ncbi.nlm.nih.gov/articles/PMC7719862/
The purpose of this study was to automatically diagnose odontogenic cysts and tumors of both jaws on panoramic radiographs using deep learning. […] The CNN method we developed for automatically diagnosing odontogenic cysts and tumors of both jaws on panoramic radiographs using data augmentation showed high sensitivity, specificity, accuracy, and AUC despite the limited number of panoramic images involved. […] The deep CNN method we developed for automatically diagnosing odontogenic cysts and tumors in both jaws on panoramic radiographs showed high sensitivity, specificity, accuracy, and AUC when using augmented data, despite the limited number of panoramic images available.