Szczepionka przeciwko wirusowemu zapaleniu wątroby typu b
Objawy

Szczepionka przeciwko wirusowemu zapaleniu wątroby typu B (HBV) wykazuje wysoką skuteczność profilaktyczną, zapewniając ochronę u 90% dorosłych i ponad 98% niemowląt po pełnym schemacie trzech dawek. Ochrona przed przewlekłym zakażeniem utrzymuje się nawet do 20-30 lat, a skuteczność przedekspozycyjna wynosi 80-100%, wzrastając do 85-95% przy jednoczesnym podaniu immunoglobuliny. Najczęstsze działania niepożądane to reakcje miejscowe (ból, zaczerwienienie, obrzęk u około 30% pacjentów) oraz łagodne objawy ogólnoustrojowe, takie jak gorączka, ból głowy, zmęczenie czy nudności, ustępujące zwykle w ciągu 1-2 dni. Rzadziej obserwuje się objawy grypopodobne, bóle mięśni, limfadenopatię czy reakcje skórne, a bardzo rzadko – anafilaksję (1,1/1 000 000 dawek) oraz poważne schorzenia neurologiczne, w tym zespół Guillaina-Barrégo, CIDP czy ADEM. Związek przyczynowy ciężkich działań niepożądanych ze szczepionką nie został jednoznacznie potwierdzony.

Symptomy szczepionki przeciwko wirusowemu zapaleniu wątroby typu b

Szczepionka przeciwko wirusowemu zapaleniu wątroby typu b jest stosowana w celu zapobiegania infekcji wirusem zapalenia wątroby typu B (HBV). Działa poprzez stymulowanie organizmu do wytwarzania własnej ochrony (przeciwciał) przeciwko tej chorobie1. Jest to szczepionka o wysokim profilu bezpieczeństwa, jednak jak każdy produkt medyczny może powodować działania niepożądane. Poniżej omówiono najczęstsze i rzadsze objawy obserwowane po podaniu szczepionki przeciwko wirusowemu zapaleniu wątroby typu b.

Najczęstsze działania niepożądane

Najczęściej występujące działania niepożądane po podaniu szczepionki przeciwko wirusowemu zapaleniu wątroby typu b to reakcje miejscowe oraz łagodne objawy ogólnoustrojowe12. Obejmują one:

Te objawy niepożądane są zwykle łagodne i ustępują samoistnie w ciągu 1-2 dni12. Objawy miejscowe w miejscu wstrzyknięcia mogą utrzymywać się przez kilka dni1. Według badań, ból, zaczerwienienie lub obrzęk w miejscu wstrzyknięcia występuje u około 30% pacjentów1.

Reakcje występujące niezbyt często

U niektórych osób mogą wystąpić mniej powszechne działania niepożądane (u około 1 na 100 osób)1:

  • Zawroty głowy lub dezorientacja12
  • Bóle mięśni1
  • Objawy grypopodobne12
  • Ból lub dyskomfort w jamie brzusznej1

Reakcje rzadkie

Rzadko (do 1 na 1000 osób) po szczepieniu przeciwko wirusowemu zapaleniu wątroby typu b mogą wystąpić1:

Działania niepożądane o nieznanej częstotliwości

Niektóre reakcje niepożądane zostały zgłoszone, ale ich dokładna częstotliwość występowania nie jest określona. Obejmują one1:

Ciężkie działania niepożądane

Ciężkie działania niepożądane po szczepieniu przeciwko wirusowemu zapaleniu wątroby typu b występują bardzo rzadko12. Należą do nich:

Reakcje anafilaktyczne

Anafilaksja jest bardzo rzadkim, ale poważnym działaniem niepożądanym, które może wystąpić po podaniu szczepionki przeciwko wirusowemu zapaleniu wątroby typu b. Według danych statystycznych, ryzyko anafilaksji wśród osób otrzymujących szczepionkę wynosi około 1,1 przypadku na milion dawek szczepionki1. Objawy anafilaksji mogą obejmować12:

  • Wysypka lub pokrzywka1
  • Obrzęk twarzy i gardła12
  • Trudności w oddychaniu12
  • Szybkie bicie serca1
  • Zawroty głowy1
  • Osłabienie1
  • Kaszel lub świszczący oddech1
  • Ucisk w gardle1
  • Niezdolność do mówienia1

Reakcja anafilaktyczna wymaga natychmiastowej pomocy medycznej. Osoby podające szczepionkę są przeszkolone w zakresie rozpoznawania i natychmiastowego leczenia takich reakcji1. Większość przypadków można opanować za pomocą adrenaliny (epinefryny), jednak niektóre przypadki mogą wymagać dodatkowego leczenia, takiego jak dożylne podawanie płynów, tlen, sterydy i leki przeciwhistaminowe1.

Inne rzadkie ciężkie działania niepożądane

Do bardzo rzadkich poważnych działań niepożądanych, które zostały zgłoszone po szczepieniu przeciwko wirusowemu zapaleniu wątroby typu b, należą12:

Należy podkreślić, że powyższe ciężkie działania niepożądane są niezwykle rzadkie, a związek przyczynowy ze szczepionką przeciwko wirusowemu zapaleniu wątroby typu b nie został jednoznacznie potwierdzony w większości przypadków1.

Progresja choroby wirusowego zapalenia wątroby typu b

Aby lepiej zrozumieć znaczenie szczepienia, ważne jest poznanie naturalnego przebiegu infekcji wirusem zapalenia wątroby typu B oraz jej potencjalnych konsekwencji.

Ostre wirusowe zapalenie wątroby typu B

Zakażenie wirusem HBV może początkowo przebiegać bezobjawowo. Osoby zakażone często nie mają żadnych objawów, zwłaszcza dzieci poniżej 5 roku życia oraz osoby z obniżoną odpornością12. Prawdopodobieństwo wystąpienia objawów klinicznych ostrego zakażenia HBV jest większe u osób starszych niż u młodszych1.

Gdy objawy wystąpią, pojawiają się zazwyczaj w ciągu 1-4 miesięcy od zakażenia, ale mogą pojawić się już po 2 tygodniach1. Średni czas od ekspozycji do pojawienia się żółtaczki wynosi około 90 dni, a do pojawienia się nieprawidłowych wyników badań ALT (aminotransferazy alaninowej) wskazujących na uszkodzenie wątroby – około 60 dni1.

Objawy ostrego wirusowego zapalenia wątroby typu B mogą obejmować12:

  • Gorączkę12
  • Zmęczenie i osłabienie12
  • Utratę apetytu12
  • Nudności i wymioty12
  • Ból brzucha12
  • Bóle stawów12
  • Ciemny mocz12
  • Jasno zabarwione (gliniaste) stolce12
  • Żółtaczkę (zażółcenie skóry i białek oczu)12

Objawy zwykle utrzymują się przez kilka tygodni, ale niektóre osoby mogą odczuwać objawy przez okres do sześciu miesięcy1. U około 1% osób z ostrym zakażeniem HBV może rozwinąć się piorunujące zapalenie wątroby, czyli ostra niewydolność wątroby, która może prowadzić do śmierci1.

Przewlekłe wirusowe zapalenie wątroby typu b

Przewlekłe zakażenie HBV rozwija się, gdy wirus pozostaje w organizmie przez ponad 6 miesięcy1. Ryzyko rozwoju przewlekłego zakażenia jest odwrotnie proporcjonalne do wieku osoby w momencie zakażenia HBV1:

  • U niemowląt zakażonych okołoporodowo HBV, 80-90% rozwija przewlekłą chorobę1
  • U dzieci zakażonych poporodowo do 5 roku życia, 30% rozwija zakażenie przewlekłe1
  • U dorosłych, mniej niż 5-10% rozwija zakażenie przewlekłe12

Większość osób z przewlekłym zapaleniem wątroby typu B nie ma objawów12. Mogą one nie pojawić się przez 20-30 lat1. Niektóre osoby mogą mieć przewlekłe zmęczenie i łagodne objawy ostrego zapalenia wątroby1.

Przewlekłe zakażenie HBV może prowadzić do poważnych powikłań, takich jak12:

Około 15-25% osób z przewlekłym zapaleniem wątroby typu B rozwija poważne problemy z wątrobą, takie jak marskość lub rak wątroby1. Według danych, każdego roku w USA około 1800 osób umiera z powodu chorób wątroby związanych z zapaleniem wątroby typu B1.

Skuteczność szczepionki przeciwko wirusowemu zapaleniu wątroby typu b

Szczepionka przeciwko wirusowemu zapaleniu wątroby typu b jest wysoce skuteczna w zapobieganiu zakażeniu HBV1. Badania wykazały, że:

  • 90% dorosłych i ponad 98% niemowląt uzyskuje dobrą ochronę przed wirusowym zapaleniem wątroby typu B po szczepieniu1
  • Pełne szczepienie trzema dawkami szczepionki zapobiega 90% zakażeń wirusem zapalenia wątroby typu B u osób, które są narażone na kontakt z wirusem1
  • Ochrona przed długotrwałym zakażeniem wirusowym zapaleniem wątroby typu B może utrzymywać się nawet przez 20-30 lat po szczepieniu1

Szczepionka przeciwko wirusowemu zapaleniu wątroby typu b ma skuteczność przedekspozycyjną wynoszącą 80-100%, a jeśli podawana jest w połączeniu z immunoglobuliną przeciwko wirusowemu zapaleniu wątroby typu b, szczepionka jest skuteczna w 85-95% w zapobieganiu przewlekłemu zakażeniu po ekspozycji na HBV1.

Po szczepieniu odporność na HBV wydaje się być dożywotnia, a dawki przypominające szczepionki nie są rutynowo zalecane1. Szczepionka może być mniej skuteczna u niektórych osób, takich jak osoby z niewydolnością nerek, dlatego czasami potrzebne są dodatkowe dawki1.

Warto podkreślić, że szczepionka przeciwko wirusowemu zapaleniu wątroby typu b jest nazywana pierwszą szczepionką przeciwnowotworową, ponieważ zapobiega wirusowemu zapaleniu wątroby typu B, które jest główną przyczyną raka wątroby na świecie1.

Wnioski dotyczące bezpieczeństwa szczepionki

Szczepionka przeciwko wirusowemu zapaleniu wątroby typu b jest uważana za niezwykle bezpieczną12. Do tej pory podano ponad miliard dawek tej szczepionki na całym świecie i jest ona uważana za jedną z najbezpieczniejszych i najskuteczniejszych szczepionek, jakie kiedykolwiek stworzono1.

Badania bezpieczeństwa szczepionki nie wykazały nowych ani nieoczekiwanych obaw dotyczących bezpieczeństwa1. Nie wykazano również zwiększonej częstości występowania zespołu Guillaina-Barrégo wśród osób zaszczepionych1. Kilka badań oceniało możliwy związek między szczepieniem przeciwko wirusowemu zapaleniu wątroby typu b a stwardnieniem rozsianym lub zapaleniem nerwu wzrokowego, jednak badania te nie wykazały żadnego związku12.

Badanie porównujące zgony wśród noworodków zaszczepionych przeciwko wirusowemu zapaleniu wątroby typu b i niezaszczepionych noworodków nie wykazało różnic między zaszczepionymi a niezaszczepionymi noworodkami1. W 4-letnim przeglądzie serii przypadków zgłoszeń szczepień przeciwko wirusowemu zapaleniu wątroby typu b wśród noworodków nie stwierdzono poważnych problemów zdrowotnych związanych ze szczepionką przeciwko wirusowemu zapaleniu wątroby typu b1.

Warto podkreślić, że ryzyko związane z zakażeniem wirusem zapalenia wątroby typu B i jego potencjalnie śmiertelnymi konsekwencjami znacznie przewyższa ryzyko związane ze szczepionką1. Szczepionka przeciwko wirusowemu zapaleniu wątroby typu b jest stale monitorowana pod kątem bezpieczeństwa, a korzyści i działania niepożądane tej szczepionki przewyższają ryzyko zachorowania na wirusowe zapalenie wątroby typu B1.

Nie można zarazić się wirusowym zapaleniem wątroby typu B od szczepionki12, ponieważ szczepionka zawiera inaktywowany (martwy) wirus lub jest produkowana przy użyciu modyfikowanych drożdży, które zawierają antygeny wirusa zapalenia wątroby typu B12.

Podsumowując, szczepionka przeciwko wirusowemu zapaleniu wątroby typu b jest bezpieczną i skuteczną metodą zapobiegania infekcji HBV i jej potencjalnie poważnym konsekwencjom zdrowotnym, takim jak przewlekłe zapalenie wątroby, marskość wątroby i rak wątrobowokomórkowy.

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  1. 13.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Hepatitis b vaccine (intramuscular route) – Mayo Clinic
    https://www.mayoclinic.org/drugs-supplements/hepatitis-b-vaccine-intramuscular-route/description/drg-20068700
    Hepatitis B vaccine recombinant is used to prevent infection by the hepatitis B virus. The vaccine works by causing your body to produce its own protection (antibodies) against the disease. […] This vaccine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor right away if you or your child have a rash, itching, swelling of the tongue and throat, or trouble breathing after you get the injection. […] Check with your doctor or nurse immediately if any of the following side effects occur: Fever of 37.7 degrees C (100 degrees F) or higher. […] Aches or pain in the joints, fever, or skin rash or welts (may occur days or weeks after receiving the vaccine). […] Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Dizziness, headache, soreness at the injection site. […] Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
  • #1 Hepatitis B Vaccine Safety | Vaccine Safety | CDC
    https://www.cdc.gov/vaccine-safety/vaccines/hepatitis-b.html
    Hepatitis B is a vaccine-preventable liver infection caused by HBV. Hepatitis B can range from a mild, short-term, acute illness lasting a few weeks to a serious, long-term, chronic infection. […] Common side effects include pain, soreness, redness, or swelling in the arm where the shot was given. Headache. Fever. Fatigue. Irritability, diarrhea, loss of appetite in healthy infants and children who received (Recombivax, Vaxelis, Pediarix). Vomiting, crying, drowsiness in children (Vaxelis, Pediarix). […] Vaccines, like any medicine, can have side effects. Many people who get a hepatitis B vaccine have no side effects at all. The most common side effects include injection site pain, soreness, or redness, headache, and fatigue, and are usually mild lasting 1-2 days. […] A Vaccine Safety Datalink (VSD) study compared deaths among newborns vaccinated with hepatitis B and unvaccinated newborns. The study found no differences between vaccinated and unvaccinated newborns.
  • #1 Hepatitis B Virus Vaccine Intramuscular: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing – WebMD
    https://www.webmd.com/drugs/2/drug-63870/hepatitis-b-virus-vaccine-intramuscular/details
    This vaccine is used to help prevent hepatitis B. Hepatitis B infection can cause serious problems including liver failure, long-term hepatitis B infection, cirrhosis, and liver cancer. […] Pain/soreness/redness/swelling at the injection site, fever, headache, tiredness, sore throat, nausea, diarrhea, and loss of appetite may occur. If any of these effects last or get worse, tell your health care professional promptly. […] Rarely, some people have symptoms such as fainting, dizziness, vision changes, or ringing in the ears just after getting a vaccine injection. Tell your health care professional right away if you have any of these symptoms. […] A very serious allergic reaction to this vaccine is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
  • #1 Hepatitis B vaccine | Healthify
    https://healthify.nz/medicines-a-z/h/hepatitis-b-vaccine
    Hepatitis B vaccine gives protection against infection from the hepatitis B virus. The vaccine works by causing the body to produce antibodies against the virus responsible for hepatitis B infection and in this way protects (or provides immunity) against the disease. […] Like all medicines, vaccines can cause side effects, although not everyone gets them. […] Pain, swelling and redness at the injection site (hard and sore to touch) […] It’s quite common for the first 1 or 2 days after receiving the injection and usually settles within a few days. […] Feeling unwell, tired or weak […] These are quite common for the first 1 or 2 days after getting the injection. […] Signs of an allergic reaction such as skin rash, itches, swelling of your face, lips, mouth or problems breathing.
  • #1 Immunization Reactions
    https://www.seattlechildrens.org/conditions/a-z/immunization-reactions/
    No serious reactions reported. […] Sore shot site occurs in 30% of children and mild fever in 3% of children. […] Fever from the vaccine is rare. Any baby under 2 months with a fever after this shot should be examined.
  • #1 Hepatitis B Vaccine | Vaccine Knowledge Project
    https://vaccineknowledge.ox.ac.uk/hepatitis-b-vaccine
    Uncommon – affecting up to 1 in 100 people at each dose: feeling dizzy, aching muscles, flu-like symptoms. […] Rare – affecting up to 1 in 1000 people at each dose: low blood pressure, joint pain (arthralgia), hives, rash or itchiness, pins and needles (paraesthesia), swollen glands in the neck, armpit or groin (lymphadenopathy). […] More serious side effects are very rare (affecting fewer than 1 in 10,000 people at each dose). You should consult your doctor if you or your child experiences suspected serious side effects after vaccination. […] As with any vaccine, medicine or food, there is a very small chance of a severe allergic reaction – anaphylaxis. Anaphylaxis is different from less severe allergic reactions because it causes life-threatening breathing and/or circulation problems.
  • #1 Hepatitis B vaccine: Safety and side effects
    https://www.medicalnewstoday.com/articles/324208
    There are several possible side effects of the hepatitis B vaccine, including headaches, nausea, and vomiting. However, the risks are minimal and the vaccine is very effective at preventing the virus. […] Hepatitis B may not cause symptoms and will clear up without treatment in some cases. In other cases, however, it will require treatment and can cause issues such as digestive problems and flu-like symptoms. It can also have serious consequences, including permanent liver damage. […] The hepatitis B vaccine causes common side effects in around 1 in 10 people who have it. […] Common side effects of the hepatitis B vaccine include: discomfort around the injection site for hours or days after getting the shot, headache, nausea, vomiting, diarrhea, high temperature, fatigue, irritability, stomach pain.
  • #1 Hepatitis B Adult Vaccine Side Effects: Common, Severe, Long Term
    https://www.drugs.com/sfx/hepatitis-b-adult-vaccine-side-effects.html
    Some side effects of hepatitis b adult vaccine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. […] Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: […] Along with its needed effects, hepatitis b adult vaccine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. […] Check with your doctor or nurse immediately if any of the following side effects occur while taking hepatitis b adult vaccine: […] Apparent hypersensitivity syndrome (serum sickness-like) of delayed onset has been reported days to weeks after vaccination, including: arthralgia/arthritis (usually transient), fever, and dermatologic reactions such as urticaria, erythema multiforme, ecchymosis, and erythema nodosum. […] Hepatitis b adult vaccine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
  • #1 A real-world pharmacovigilance analysis of hepatitis B vaccine using the U.S. Vaccine Adverse Event Reporting System (VAERS) database | Scientific Reports
    https://www.nature.com/articles/s41598-025-90135-8
    Among the positive PTs, Urticaria, Drugs ineffective, Product storage error, Agitation, Crying, Injections site hypersensitivity, and Injection site oedema were relatively high. […] Among all the detected signals, those related to the DME include Anaphylactoid reaction, Angioedema, Aplastic anaemia, Dermatitis exfoliative, Erythema multiforme, Haemolytic anaemia, and Hepatic failure. […] Four PTs, namely Aplastic anaemia, Dermatitis exfoliative, Haemolytic anaemia, and Hepatic failure were identified as potential new signals and warrant further monitoring. […] Therefore, patients with pre-existing autoimmune diseases should be closely monitored after hepatitis B vaccination, and measures should be taken promptly if symptoms such as pallor, jaundice, or tachycardia occur.
  • #1 Hepatitis B vaccine – NHS
    https://www.nhs.uk/vaccinations/hepatitis-b-vaccine/
    Hepatitis B can be very serious. It can make the liver suddenly stop working or cause gradual damage to the liver over time. It can also increase your chances of getting liver cancer. […] Most of the side effects of the hepatitis B vaccine are mild and do not last long. They can include: swelling or pain where the injection was given, feeling tired, sleepy or irritable, a headache, feeling or being sick, diarrhoea, a stomach ache, a high temperature. […] More serious side effects such as a severe allergic reaction are very rare. The person who vaccinates you will be trained to deal with allergic reactions and treat them immediately. […] The hepatitis B vaccine works very well at helping protect people against hepatitis B. Research has shown that: 90% of adults and over 98% of babies have good protection from hepatitis B after being vaccinated, protection against long-term hepatitis B infection could last for as long as 20 to 30 years after being vaccinated. […] The vaccine can work less well in some people, such as people with kidney failure, so extra doses are sometimes needed.
  • #1 Hepatitis B Vaccine: Uses, Side Effects, Dosage, Precautions
    https://www.verywellhealth.com/hepatitis-b-vaccine-and-why-you-need-it-1760037
    Hepatitis B vaccines are used to prevent hepatitis B, a viral infection of the liver that can lead to cirrhosis, liver failure, and liver cancer in some people. […] Hepatitis vaccines may cause side effects, although they tend to be mild and resolve within a day or two. Severe side effects are rare. […] The list of common side effects are similar for all four hepatitis B vaccines. They include: Injection site pain, Injection site swelling, Headache, Fatigue, Malaise, Nausea, Diarrhea, Dizziness, Fever over 100 degrees F. […] Injection site reactions are more common with Heplisav-B, in part because it contains a substance called cytosine phosphoguanine. This acts as an adjuvant, an ingredient that amplifies the body’s response to vaccines. […] Severe side effects of hepatitis vaccines are rare. According to the World Health Organization, there is no evidence of serious adverse events linked to hepatitis B vaccination. This includes the risk of a potentially life-threatening allergic reaction known as anaphylaxis. […] Statistically, the risk of anaphylaxis among vaccine recipients is in the ballpark of 1.1 cases per million vaccine doses.
  • #1 Hepatitis B Vaccine: Side Effects, Benefits, and More
    https://www.healthline.com/health/hepatitis-b-vaccine-side-effects
    Hepatitis B vaccine may cause some mild side effects. The most common symptom is redness, swelling, or soreness where the injection was given. Some people also experience headache or fever. These effects usually last a day or two. […] Rarely, some people have a serious and potentially life threatening allergic reaction to the vaccine. Call 911 or get to a hospital immediately if you experience any of the following symptoms after vaccination: hives, swelling in your face and throat, dizziness, weakness, difficulty breathing, rapid heartbeat. […] The hepatitis B vaccine is extremely safe. As with any medication, there is a small risk of serious issues after vaccination. […] Although some people rarely experience serious side effects, its most likely that youll have few if any side effects.
  • #1 Hepatitis A And B Vaccine Side Effects: How Long Do They Last? | Jeffrey S. Pop & Associates
    https://www.vaccineinjuryteam.com/blog/2023/october/hepatitis-a-and-b-vaccine-side-effects-how-long-/
    Some severe side effects of Hep A and B vaccines include SIRVA, allergic reactions, vasovagal Syncope, ADEM, CIDP, and more. […] Symptoms often include sudden and ongoing rash, tongue swelling, difficulty breathing, coughing or wheezing, hives, tightness in your throat, and inability to speak. […] Most cases will resolve with a dose from an EpiPen. However, some cases require additional treatment like IV fluids, oxygen, steroids, and antihistamines. […] Patients will experience the onset of GBS within a few weeks of getting a Hep A or B vaccine. It can happen anywhere between three to 42 days after a vaccine. […] If you suffer from GBS, you will see signs of numbness or tingling in your hands and feet at the initial onset. You can lose your ability to walk or feel anything over time.
  • #1 8 Hepatitis B Vaccine | Adverse Effects of Vaccines: Evidence and Causality | The National Academies Press
    https://nap.nationalacademies.org/read/13164/chapter/10
    HBV-infected individuals are often asymptomatic. Clinical symptoms of acute HBV infection are more likely in older individuals than in younger individuals. When manifested, symptoms may include fever, fatigue, nausea, vomiting, and abdominal pain before progressing to clay-colored stools, dark urine, and jaundice indicating increased liver involvement and cholestasis—the accumulation of bile in the liver. Extrahepatic manifestations of hepatitis B can include arthritis, urticaria, vasculitis, and glomerulonephritis. Symptomatic infection generally presents within the first 6 months of exposure averaging 90 days from exposure to jaundice and 60 days to abnormal serum alanine aminotransferase (ALT) levels indicating liver injury. […] Approximately 95 percent of all hepatitis B infections among otherwise healthy adults resolve without sequelae, and the recovered individual possesses lifelong immunity to HBV infection. In the other 5 percent, chronic infection develops. Chronic HBV infection may lead to liver cirrhosis, liver failure, hepatocellular carcinoma, or death. These outcomes are thought to be the result of the constant activity of the immune system and not a direct consequence of damage caused by the virus itself. The likelihood of chronic hepatitis B disease is inversely related to the age of the individual at the time of HBV infection. Among infants perinatally infected with HBV, 80-90 percent develop chronic disease; among children infected postnatally through 5 years of age, 30 percent; and among adults, fewer than 5 percent. The risk of chronic disease may be higher in the immunocompromised and diabetics dependent on finger-stick monitoring devices.
  • #1 Hepatitis A and B Vaccine Side Effects and Reactions
    https://shannonlawgroup.com/vaccine-injury-lawyer/hepatitis-a-b-vaccine-reactions/
    Guillain-Barre Syndrome is an autoimmune disorder in which the immune system begins attacking nerves responsible for walking, talking, and more. As a result, patients with GBS slowly lose control over their movements. […] GBS is often triggered by a viral infection. However, it can also be caused by a vaccination. […] The onset of vaccine-related GBS occurs within 3 to 42 days. People will often experience tingling or numbness in their hands and feet. Over time, they will lose the ability to feel and walk.
  • #1 Hepatitis B Vaccine: Benefits, Side Effects, and Legal Help
    https://www.myvaccinelawyer.com/vaccine-injury-lawyer/resources/vaccine/hepatitis-b/
    The Hepatitis B vaccine is very important to prevent severe liver infections in children and adults. It can cause side effects like soreness, fever, and rarely, severe reactions such as anaphylaxis and neurological issues. […] Although rare, you may suffer a more severe reaction or injury as a result of the Hepatitis B vaccination. According to the Vaccine Injury Table, some of the possible injuries of the Hepatitis B vaccine include: Anaphylaxis, Shoulder injury (at the injection site), Fainting. […] It’s very rare for the Hepatitis B vaccine to cause long-term problems because it’s a very safe vaccine. Most people don’t have serious side effects that last a long time. Very rarely, some people have reported feeling weak or having tingling sensations, but this is not common. Hepatitis B vaccines long term side effects or worsening symptoms could also be early signs of serious illness including Guillain-Barre Syndrome („GBS”), Chronic Inflammatory Demyelinating Polyneuropathy („CIDP”), optic neuritis, Transverse Myelitis and Parsonage-Turner Syndrome („PTS”). Improper administration of the vaccination, can also result in shoulder-related injuries. Any neurological problems or other health issues you suffer after being vaccinated with Hepatitis B could be related to the inoculation.
  • #1 Hepatitis A and B Vaccine Side Effects and Reactions
    https://shannonlawgroup.com/vaccine-injury-lawyer/hepatitis-a-b-vaccine-reactions/
    Since 1994, the Hepatitis A (“Hep A”) and Hepatitis B (“Hep B”) vaccines have protected millions of Americans from contracting these deadly viruses. […] While Hep A and B vaccinations offer necessary protection for most, these vaccines can cause serious adverse reactions and injuries in some. These side effects include shoulder injuries (SIRVA), Vasovagal Syncope, allergic reactions, Guillain-Barre Syndrome (GBS), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Acute Disseminated Encephalomyelitis (ADEM) and other injuries. […] For some, a hepatitis B infection is mild and doesn’t last long. They may experience symptoms such as a fever, nausea, tiredness, loss of appetite, vomiting, jaundice, and other side effects. […] However, others may experience a chronic infection that may not show any symptoms. Chronic hepatitis B can lead to severe health conditions, such as liver cancer or cirrhosis (chronic damage of the liver).
  • #1 Hepatitis B Vaccine Guide | Immunization Info
    https://immunizationinfo.com/hepatitis-b/
    The Hepatitis B vaccine is an immunization against all known subtypes of the Hepatitis B virus (HBV). […] Full immunization with 3 doses of the vaccine will prevent 90% of Hepatitis B infections in people who are exposed to the virus. […] The most common Hepatitis B vaccine side effect is soreness where the shot was injected. Up to 10% of people experience fatigue, dizziness, headache, or a fever over 100°F. […] The following is a list of severe side effects that have been reported in people who received the Hepatitis B. These side effects are so rare, it is unknown if they were actually caused by the vaccine: Abnormal liver function tests, allergic reaction, angioedema, apnea (temporarily stop breathing), asthma-like symptoms, back pain, Bell’s palsy, eczema, encephalitis, enlarged lymph nodes, erythema multiforme, facial paralysis, fainting, flu-like symptoms, gastrointestinal constipation, diarrhea, vomiting, Guillain-Barré syndrome, hair loss, heart palpitations, joint pain, meningitis, migraine, multiple sclerosis, nerve damage, neuritis, neuropathy including hypoesthesia (numbness), optic neuritis, paralysis, seizures, serum sickness, shoulder injury related to vaccine administration, SIRVA, skin reactions, Stevens-Johnson syndrome, thrombocytopenia, transverse myelitis, Guillain-Barré syndrome, upper respiratory tract infection, vasculitis, weakness.
  • #1 Hepatitis A and B Vaccine Side Effects and Reactions
    https://shannonlawgroup.com/vaccine-injury-lawyer/hepatitis-a-b-vaccine-reactions/
    Mild to moderate side effects may occur following a Hep A or Hep B vaccination. Most of the time, these reactions go away on their own within days or weeks. […] Following a hepatitis vaccine, you may experience the following adverse reactions: Soreness or redness where the shot is given, Headache, Loss of appetite, Fever, Tiredness or fatigue. […] As with any medication, there is a small chance you may become seriously injured by a hepatitis A or B vaccination. The hepatitis A and hepatitis B vaccines have been linked to the following conditions by the National Vaccine Injury Compensation Program (VICP): […] Vasovagal syncope happens when you faint due to an overreaction to a trigger like a vaccination. Your heart rate and blood pressure drop suddenly, causing you to faint. […] Like with any vaccination, people may experience anaphylactic shock following a hepatitis A or hepatitis B vaccination. This reaction is very rare. It often occurs within minutes or hours after the injection is given.
  • #1 Hepatitis B – immunisation | Better Health Channel
    https://www.betterhealth.vic.gov.au/health/healthyliving/hepatitis-b-immunisation
    Side effects from the vaccine are uncommon and usually mild, but may include: localized pain, redness and swelling at the injection site, low-grade temperature (fever), in children being unsettled, irritable, tearful, generally unhappy, drowsy and tired, occasionally, an injection-site lump (nodule) that may last many weeks, but for which treatment is not needed. […] Common side effects following immunisation are usually mild and temporary (occurring in the first few days after vaccination). Specific treatment is not usually required. […] If the side effect following immunisation is unexpected, persistent or severe, or if you are worried about yourself or your child’s condition after a vaccination, see your doctor or immunisation nurse as soon as possible or go directly to a hospital. […] There is a very rare risk of a serious allergic reaction (anaphylaxis) to any vaccine. […] Another rare side effect is the hypotonic-hyporesponsive episode (HHE). If they are experiencing HHE, a baby may be: pale, limp, unresponsive. […] Follow-up of children with HHE shows no long-term neurological or other side effects.
  • #1 Hepatitis B Vaccine Safety | Vaccine Safety | CDC
    https://www.cdc.gov/vaccine-safety/vaccines/hepatitis-b.html
    CDC reviewed VAERS reports of adverse events following hepatitis B vaccination from 2005 through 2015. During that time, 20,231 reports following hepatitis B or hepatitis B-containing vaccines, were submitted to VAERS. Over half of reports were in persons younger than 2 years of age; the majority of reports (78%) were following hepatitis B-containing vaccines in combination with other vaccines at the same visit. The most frequently reported adverse events for vaccines given in combination were fever, injection site redness, and vomiting. This review of the hepatitis B vaccine did not detect any new or unexpected safety concerns. These findings are consistent with pre-licensure clinical trials and other post-licensure monitoring and research. […] In a 4-year case series review of hepatitis B vaccine reports among newborns, there were no serious health problems linked to the hepatitis B vaccine. This was the largest case series review of hepatitis B vaccination reports among newborn babies and infants. Several studies have evaluated a possible link between hepatitis B vaccination and multiple sclerosis or optic neuritis. The studies did not show any link.
  • #1 Hepatitis B Vaccine – Adverse Effects of Vaccines – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK190035/
    HBV-infected individuals are often asymptomatic. Clinical symptoms of acute HBV infection are more likely in older individuals than in younger individuals. When manifested, symptoms may include fever, fatigue, nausea, vomiting, and abdominal pain before progressing to clay-colored stools, dark urine, and jaundice indicating increased liver involvement and cholestasis the accumulation of bile in the liver. Extrahepatic manifestations of hepatitis B can include arthritis, urticaria, vasculitis, and glomerulonephritis. Symptomatic infection generally presents within the first 6 months of exposure averaging 90 days from exposure to jaundice and 60 days to abnormal serum alanine aminotransferase (ALT) levels indicating liver injury. […] Approximately 95 percent of all hepatitis B infections among otherwise healthy adults resolve without sequelae, and the recovered individual possesses lifelong immunity to HBV infection. In the other 5 percent, chronic infection develops. Chronic HBV infection may lead to liver cirrhosis, liver failure, hepatocellular carcinoma, or death. These outcomes are thought to be the result of the constant activity of the immune system and not a direct consequence of damage caused by the virus itself. The likelihood of chronic hepatitis B disease is inversely related to the age of the individual at the time of HBV infection.
  • #1 Hepatitis B – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/hepatitis-b/symptoms-causes/syc-20366802
    Hepatitis B is a serious liver infection caused by the hepatitis B virus (HBV). For most people, hepatitis B is short term, also called acute. Acute hepatitis B lasts less than six months. But for others, the infection lasts more than six months and is called chronic. Chronic hepatitis B raises the risk of liver failure, liver cancer and serious scarring of the liver called cirrhosis. […] Most adults with hepatitis B recover fully, even if their symptoms are bad. Infants and children are more likely to develop a chronic, long-lasting hepatitis B virus infection. […] Symptoms of acute hepatitis B range from mild to serious. The symptoms usually start about 1 to 4 months after you’ve been infected with HBV. But you could notice them as early as two weeks after you’re infected. Some people with acute or chronic hepatitis B may not have any symptoms, especially young children.
  • #1 Hepatitis B – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/hepatitis-b/symptoms-causes/syc-20366802
    Hepatitis B symptoms may include: Pain in the stomach area, also called the abdomen. Dark urine. Fever. Joint pain. Loss of appetite. Upset stomach and vomiting. Weakness and extreme tiredness. Jaundice, which is a yellowing of the whites of the eyes and the skin. Depending on skin color, this change may be harder or easier to see. […] Chronic hepatitis B virus infection may last a lifetime. It can lead to serious illnesses such as cirrhosis and liver cancer. Some people with chronic hepatitis B may have no symptoms at all. Some may have ongoing tiredness and mild symptoms of acute hepatitis. […] The hepatitis B vaccine is the main way to prevent infection with HBV. The vaccine is given as two shots one month apart, or three or four shots over six months. How many shots you get depends on the type of hepatitis B vaccine that you’re given. You can’t get hepatitis B from the vaccine.
  • #1 Hepatitis B Vaccine Guide | Immunization Info
    https://immunizationinfo.com/hepatitis-b/
    The symptoms of Hepatitis B include fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, dark urine, clay-colored bowel movements, joint pain, and jaundice (yellowing of skin and eyes). […] The average time for symptoms to appear is 90 days after exposure to the virus, but the incubation period ranges from 6 weeks to 6 months. […] Symptoms usually last for a few weeks, but some people experience symptoms for up to six months. The body usually gets rid of the virus, but not always. Some people develop chronic Hepatitis B infections, but they may not have any symptoms for as long as 20 or 30 years. […] About 15-25% of people with chronic Hepatitis B develop serious liver problems like cirrhosis (scarring of the liver) or liver cancer. […] Yes. Every year, about 1,800 people in the U.S. die from Hepatitis B-related liver disease.
  • #1
    https://historyofvaccines.org/diseases/hepatitis-and-hepatitis-b/
    The symptoms of acute hepatitis A infection are identical to those of hepatitis B infection. Early symptoms are headache, nausea, vomiting, abdominal pain, fever, rash, body aches and pains, and dark colored urine. Following this phase, jaundice (yellow-colored skin and whites of the eyes), light stools, and liver pain may appear. […] Both hepatitis A and hepatitis B infection can have immediate, deadly consequences. Approximately 1% of people with acute HBV infections will suffer fulminant hepatitis, or acute liver failure. HAV infection may also, though less commonly than HBV infection, lead to fulminant hepatitis. Up to 90% of patients with fulminant hepatitis will die. […] Up to 95% of adults infected with acute HBV infection recover and do not become chronically (permanently) infected, although they can infect other people during the acute phase via transmission of body secretions. The others become chronically infected and can infect others for a much longer time (in some cases for many years) and are at risk for serious liver disease. The picture is different for children: infants and children who become infected with hepatitis B are much more likely than adults to become chronically infected and hence to develop serious, late complications. […] Chronic infection with HBV may lead to cirrhosis, liver failure, and liver cancer. HAV infection does not lead to chronic infection or chronic liver disease.
  • #1 8 Hepatitis B Vaccine | Adverse Effects of Vaccines: Evidence and Causality | The National Academies Press
    https://nap.nationalacademies.org/read/13164/chapter/10
    The hepatitis B vaccine has a preexposure efficacy of 80-100 percent, and if given in conjunction with hepatitis B immune globulin, the vaccine is 85-95 percent effective in preventing chronic infection post-HBV exposure. Following vaccination, HBV immunity appears to be lifelong, and booster doses of the vaccine are not routinely recommended.
  • #1 Hepatitis B Foundation: Hepatitis B Vaccination
    https://www.hepb.org/prevention-and-diagnosis/vaccination/
    It takes only a few shots to protect yourself and your loved ones against hepatitis B for a lifetime. […] The hepatitis B vaccine is a safe and effective vaccine that is recommended for all infants at birth and for children up to 18 years. […] The hepatitis B vaccine is also known as the first anti-cancer vaccine because it prevents hepatitis B, the leading cause of liver cancer worldwide. […] You cannot get hepatitis B from the vaccine. […] If you have a current HBV infection (HBsAg positive) or have recovered from a past HBV infection, the hepatitis B vaccine series will not benefit you or clear the virus. […] The hepatitis B vaccine is available at your doctor’s office and local health department or clinic. […] More than 1 billion doses of the hepatitis B vaccine have been given worldwide and it is considered one of the safest and most effective vaccines ever made. […] Common side effects from the hepatitis B vaccine may include soreness, swelling and redness at the injection site.
  • #1 Frequency of adverse reactions to hepatitis B vaccine in 43,618 persons – PubMed
    https://pubmed.ncbi.nlm.nih.gov/1532114/
    Possible adverse reactions occurred in 39 persons. The most frequent adverse reactions were myalgia/arthralgia lasting longer than 3 days (14), followed by skin rashes (eight) and dizziness (seven). […] No increased incidence of GBS was found in the vaccinees. […] Hepatitis B vaccine is safe and most adverse reactions are coincidental.
  • #1 Hepatitis B Vaccine: Side Effects & Reactions | Carreras Medical Center
    https://www.toplinemd.com/carreras-medical-center/hepatitis-b-vaccine-side-effects-reactions/
    In terms of safety, the hepatitis B vaccine is exceptionally safe. As with any medication, there is a small risk of serious issues arising after vaccination. However, it is essential to note that the risk of developing hepatitis B and its potentially fatal consequences far outweigh the risks associated with the vaccine. […] The hepatitis B vaccine is a true game-changer in the world of preventive medicine. It provides at least 98 percent protection to infants, children, and adults who complete the recommended vaccination schedule before exposure to the virus. […] In conclusion, while the hepatitis B vaccine may cause some mild and short-lived side effects in rare cases, its safety and effectiveness make it a vital component of public health.
  • #1 Hepatitis B | Washington State Department of Health
    https://doh.wa.gov/you-and-your-family/immunization/diseases-and-vaccines/hepatitis-b
    Not all people with a new HBV infection have symptoms. The presence of signs and symptoms varies by age. Infants, children under 5 years old, and immunosuppressed adults with a HBV infection are typically asymptomatic. People less than 30 years old are less likely to show symptoms compared with persons aged 30 years and older. When present, signs and symptoms of HBV infections can include: […] Most people with long-term HBV infection are asymptomatic and have no evidence of liver disease or injury. However, some people develop chronic hepatitis, liver scarring and failure (cirrhosis), or liver cancer (hepatocellular carcinoma). […] The most common side effect of getting a hepatitis B vaccine is having soreness at the injection site. […] This vaccine is continually monitored for safety. The benefits and side effects of this vaccine outweigh the risk of getting hepatitis B.
  • #1 Hepatitis B Vaccine: Side Effects & Reactions | Carreras Medical Center
    https://www.toplinemd.com/carreras-medical-center/hepatitis-b-vaccine-side-effects-reactions/
    Hepatitis B is a viral infection affecting the liver and can range from mild to chronic and life-threatening conditions. […] The hepatitis B vaccine is renowned for its safety and effectiveness. It is made using an inactivated (dead) virus, and most formulations of the vaccine are considered safe even for pregnant individuals. […] While the vaccine is generally well-tolerated, some individuals may experience mild side effects, the most common of which include redness, swelling, or soreness at the site of the injection. Occasionally, some may also report experiencing a headache or fever, though these effects are typically short-lived and last for only a day or two. […] In rare cases, a severe and potentially life-threatening allergic reaction may occur to the vaccine. If you experience any of the following symptoms after vaccination, it’s crucial to seek immediate medical attention: Hives, Swelling in your face and throat, Dizziness, Weakness, Difficulty breathing, Rapid heartbeat.
  • #2
    https://www.bumrungrad.com/en/health-blog/january-2025/hepatitis-b-vaccine
    The most common symptoms are local reactions at the site of injection which are mild and self-limited. Mild systemic reactions, e.g. fever, malaise, and headache, are reported (10%) after vaccination around 3-4 hours and not last longer than 24 hours. Serious systemic adverse reactions and allergic reactions are very rare.
  • #2 Hepatitis B vaccine | Healthify
    https://healthify.nz/medicines-a-z/h/hepatitis-b-vaccine
    Hepatitis B vaccine gives protection against infection from the hepatitis B virus. The vaccine works by causing the body to produce antibodies against the virus responsible for hepatitis B infection and in this way protects (or provides immunity) against the disease. […] Like all medicines, vaccines can cause side effects, although not everyone gets them. […] Pain, swelling and redness at the injection site (hard and sore to touch) […] It’s quite common for the first 1 or 2 days after receiving the injection and usually settles within a few days. […] Feeling unwell, tired or weak […] These are quite common for the first 1 or 2 days after getting the injection. […] Signs of an allergic reaction such as skin rash, itches, swelling of your face, lips, mouth or problems breathing.
  • #2 Hepatitis b vaccine (intramuscular route) – Mayo Clinic
    https://www.mayoclinic.org/drugs-supplements/hepatitis-b-vaccine-intramuscular-route/description/drg-20068700
    Hepatitis B vaccine recombinant is used to prevent infection by the hepatitis B virus. The vaccine works by causing your body to produce its own protection (antibodies) against the disease. […] This vaccine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor right away if you or your child have a rash, itching, swelling of the tongue and throat, or trouble breathing after you get the injection. […] Check with your doctor or nurse immediately if any of the following side effects occur: Fever of 37.7 degrees C (100 degrees F) or higher. […] Aches or pain in the joints, fever, or skin rash or welts (may occur days or weeks after receiving the vaccine). […] Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Dizziness, headache, soreness at the injection site. […] Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
  • #2 Hepatitis B Virus Vaccine Intramuscular: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing – WebMD
    https://www.webmd.com/drugs/2/drug-63870/hepatitis-b-virus-vaccine-intramuscular/details
    This vaccine is used to help prevent hepatitis B. Hepatitis B infection can cause serious problems including liver failure, long-term hepatitis B infection, cirrhosis, and liver cancer. […] Pain/soreness/redness/swelling at the injection site, fever, headache, tiredness, sore throat, nausea, diarrhea, and loss of appetite may occur. If any of these effects last or get worse, tell your health care professional promptly. […] Rarely, some people have symptoms such as fainting, dizziness, vision changes, or ringing in the ears just after getting a vaccine injection. Tell your health care professional right away if you have any of these symptoms. […] A very serious allergic reaction to this vaccine is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
  • #2 Hepatitis B Pediatric Vaccine Side Effects: Common, Severe, Long Term
    https://www.drugs.com/sfx/hepatitis-b-pediatric-vaccine-side-effects.html
    Common side effects may include: diarrhea, loss of appetite; feeling weak or tired; mild fussiness or crying; low fever; or runny nose. […] The most common adverse events were injection site reactions, headache, and fatigue. […] Apparent hypersensitivity syndrome (serum sickness-like) of delayed onset has been reported days to weeks after vaccination, including: arthralgia/arthritis (usually transient), fever, and dermatologic reactions such as urticaria, erythema multiforme, ecchymosis, and erythema nodosum. […] Very common (10% or more): Fatigue (33.8%). […] Very common (10% or more): Headache (23.4%).
  • #2 Hepatitis-a/b-vaccine: Side Effects, Uses, Dosage, Interactions, Warnings
    https://www.rxlist.com/hepatitis-ab-vaccine/generic-drug.htm
    Hepatitis A/B vaccine is indicated for active immunization of persons 18 years of age and older against disease caused by the hepatitis A virus and infection by all known subtypes of the hepatitis B virus. […] Common side effects of Hepatitis A/B vaccine include: injection site reactions (redness, pain, tenderness, swelling, or a hard lump), fever, sore throat, runny or stuffy nose, other cold symptoms, headache, tired feeling, nausea, vomiting, loss of appetite, diarrhea. […] Serious side effects of Hepatitis A/B vaccine include: fever, sore throat, and headache with a severe blistering, peeling, and red skin rash, fast or pounding heartbeats, easy bruising or bleeding. […] Seek medical care or call 911 at once if you have the following serious side effects: Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, coordination loss, unsteady, very stiff muscles, high fever, profuse sweating, or tremors.
  • #2 Hepatitis B Vaccine: Side Effects, Benefits, and More
    https://www.healthline.com/health/hepatitis-b-vaccine-side-effects
    Hepatitis B vaccine may cause some mild side effects. The most common symptom is redness, swelling, or soreness where the injection was given. Some people also experience headache or fever. These effects usually last a day or two. […] Rarely, some people have a serious and potentially life threatening allergic reaction to the vaccine. Call 911 or get to a hospital immediately if you experience any of the following symptoms after vaccination: hives, swelling in your face and throat, dizziness, weakness, difficulty breathing, rapid heartbeat. […] The hepatitis B vaccine is extremely safe. As with any medication, there is a small risk of serious issues after vaccination. […] Although some people rarely experience serious side effects, its most likely that youll have few if any side effects.
  • #2 Hepatitis B vaccine: Safety and side effects
    https://www.medicalnewstoday.com/articles/324208
    Uncommon side effects may occur in 1 in 100 people, with more serious side effects being rare and affecting only around 1 in 1,000 people. […] Uncommon side effects include: flu-like symptoms, muscle ache, dizziness or disorientation. […] Rare side effects include: joint pain, pins and needles, swelling, hives and rashes, low blood pressure, or hypotension. […] Most symptoms are mild and will go away on their own. It is common to experience discomfort at the injection site, which can last for 1 or 2 days. […] Consult a doctor as soon as possible if uncommon or rare side effects occur. This is important to determine whether these are symptoms of an underlying health condition or if the vaccine is the cause. […] Mild side effects are relatively common and include discomfort at the injection site. More serious side effects are rare and should not be a cause for concern for most people.
  • #2 Hepatitis B Vaccine: Uses, Side Effects, Dosage, Precautions
    https://www.verywellhealth.com/hepatitis-b-vaccine-and-why-you-need-it-1760037
    Hepatitis B vaccines are used to prevent hepatitis B, a viral infection of the liver that can lead to cirrhosis, liver failure, and liver cancer in some people. […] Hepatitis vaccines may cause side effects, although they tend to be mild and resolve within a day or two. Severe side effects are rare. […] The list of common side effects are similar for all four hepatitis B vaccines. They include: Injection site pain, Injection site swelling, Headache, Fatigue, Malaise, Nausea, Diarrhea, Dizziness, Fever over 100 degrees F. […] Injection site reactions are more common with Heplisav-B, in part because it contains a substance called cytosine phosphoguanine. This acts as an adjuvant, an ingredient that amplifies the body’s response to vaccines. […] Severe side effects of hepatitis vaccines are rare. According to the World Health Organization, there is no evidence of serious adverse events linked to hepatitis B vaccination. This includes the risk of a potentially life-threatening allergic reaction known as anaphylaxis. […] Statistically, the risk of anaphylaxis among vaccine recipients is in the ballpark of 1.1 cases per million vaccine doses.
  • #2 Hepatitis A And B Vaccine Side Effects: How Long Do They Last? | Jeffrey S. Pop & Associates
    https://www.vaccineinjuryteam.com/blog/2023/october/hepatitis-a-and-b-vaccine-side-effects-how-long-/
    Some severe side effects of Hep A and B vaccines include SIRVA, allergic reactions, vasovagal Syncope, ADEM, CIDP, and more. […] Symptoms often include sudden and ongoing rash, tongue swelling, difficulty breathing, coughing or wheezing, hives, tightness in your throat, and inability to speak. […] Most cases will resolve with a dose from an EpiPen. However, some cases require additional treatment like IV fluids, oxygen, steroids, and antihistamines. […] Patients will experience the onset of GBS within a few weeks of getting a Hep A or B vaccine. It can happen anywhere between three to 42 days after a vaccine. […] If you suffer from GBS, you will see signs of numbness or tingling in your hands and feet at the initial onset. You can lose your ability to walk or feel anything over time.
  • #2 Hepatitis B Vaccine Guide | Immunization Info
    https://immunizationinfo.com/hepatitis-b/
    The Hepatitis B vaccine is an immunization against all known subtypes of the Hepatitis B virus (HBV). […] Full immunization with 3 doses of the vaccine will prevent 90% of Hepatitis B infections in people who are exposed to the virus. […] The most common Hepatitis B vaccine side effect is soreness where the shot was injected. Up to 10% of people experience fatigue, dizziness, headache, or a fever over 100°F. […] The following is a list of severe side effects that have been reported in people who received the Hepatitis B. These side effects are so rare, it is unknown if they were actually caused by the vaccine: Abnormal liver function tests, allergic reaction, angioedema, apnea (temporarily stop breathing), asthma-like symptoms, back pain, Bell’s palsy, eczema, encephalitis, enlarged lymph nodes, erythema multiforme, facial paralysis, fainting, flu-like symptoms, gastrointestinal constipation, diarrhea, vomiting, Guillain-Barré syndrome, hair loss, heart palpitations, joint pain, meningitis, migraine, multiple sclerosis, nerve damage, neuritis, neuropathy including hypoesthesia (numbness), optic neuritis, paralysis, seizures, serum sickness, shoulder injury related to vaccine administration, SIRVA, skin reactions, Stevens-Johnson syndrome, thrombocytopenia, transverse myelitis, Guillain-Barré syndrome, upper respiratory tract infection, vasculitis, weakness.
  • #2 Hepatitis B | Sharing Knowledge About Immunisation | SKAI
    https://skai.org.au/childhood/diseases-and-vaccines/hepatitis-b
    Are there any rare/and or serious side effects to the vaccine? Babies who get a fever (for any reason) occasionally experience a fit (febrile convulsion) that lasts from a few seconds to a few minutes. Febrile convulsions dont have long-term effects on a childs health and development. Some people who get vaccines that protect against hepatitis B experience nausea or aches in their muscles or joints in the days afterwards. About 0.0032 per cent of children aged 12 months or under who get a vaccine that protects against pertussis (whooping cough) experience hypotonic-hyporesponsive episodes (HHE). These children get very pale, go limp, and dont respond to their surroundings. Their lips and fingernails can also turn blue. Most reactions last less than 30 minutes and can occur anytime from vaccination up to about 48 hours after vaccination. HHEs dont have any long-term effects on childrens health. About 0.0001 per cent of people have an allergic reaction following vaccination that affects their whole body, called anaphylaxis. This reaction usually happens within 15 minutes of getting the vaccination and can be treated by giving an injection of adrenaline. People who have this reaction usually recover quickly and dont experience any long-term effects.
  • #2 Hepatitis B | Texas DSHS
    https://www.dshs.texas.gov/vaccine-preventable-diseases/vaccine-preventable-disease-conditions/hepatitis-b
    Hepatitis B infections are vaccine-preventable liver infections caused by the Hepatitis B virus (HBV) which is a hepadnavirus. […] The presence of signs and symptoms varies by age. Most children under the age of five and newly infected immunosuppressed adults have no symptoms. For individuals over the age of five, 30%50% have initial signs and symptoms. When present, signs and symptoms can include: Fever, Fatigue, Loss of appetite, Nausea, Vomiting, Abdominal pain, Dark urine, Clay-colored bowel movements, Joint pain, Jaundice (yellowish skin or eyes). […] There are two stages to hepatitis B: acute and chronic. When first infected with hepatitis B, the person has acute hepatitis B. After that, their hepatitis B will resolve. This makes them either immune to further infection or they will become chronically infected. With chronic infection, they can infect other people and may continue to have other symptoms or complications. After acute infection, about 90% of infants and 30% of children under five years of age will become chronically infected compared to about 5% of adults. […] People with chronic HBV infection might show no symptoms, have no evidence of liver disease, or have a spectrum of diseases ranging from chronic hepatitis to cirrhosis or hepatocellular carcinoma (a type of liver cancer).
  • #2 Hepatitis B vaccine – what you need to know Information | Mount Sinai – New York
    https://www.mountsinai.org/health-library/special-topic/hepatitis-b-vaccine-what-you-need-to-know
    Hepatitis B vaccine can prevent hepatitis B. Hepatitis B is a liver disease that can cause mild illness lasting a few weeks, or it can lead to a serious, lifelong illness. […] Acute hepatitis B is a short-term illness that can lead to fever, fatigue, loss of appetite, nausea, vomiting, jaundice (yellow skin or eyes, dark urine, clay-colored bowel movements), and pain in the muscles, joints, and stomach. […] Chronic hepatitis B is a long-term illness that occurs when the hepatitis B virus remains in a person’s body. Most people who go on to develop chronic hepatitis B do not have symptoms, but it is still very serious and can lead to liver damage (cirrhosis), liver cancer, and death. […] Risks of a vaccine reaction include soreness where the shot is given, fever, headache, and fatigue (feeling tired) can happen after hepatitis B vaccination. […] As with any medicine, there is a very remote chance of a vaccine causing a severe allergic reaction, other serious injury, or death.
  • #2 Hepatitis B: What It Is, Symptoms, Transmission & Treatment
    https://my.clevelandclinic.org/health/diseases/4246-hepatitis-b
    Hepatitis B is a viral infection that causes inflammation in your liver. It can be a brief illness that may not cause symptoms and goes away without treatment. This is acute hepatitis B. But some people have a chronic (long-term) form of the virus. It can lead to cirrhosis and liver failure. […] Symptoms of hepatitis B infection, if you have them, include fever, nausea and abdominal pain. Not everyone has symptoms with hepatitis B, but common symptoms include fever, nausea and abdominal pain. […] You can have hepatitis B without having symptoms. If you do, symptoms may include: Abdominal pain, Fatigue, Fever, Joint pain, Loss of appetite, Nausea and vomiting, Weakness. […] You may also have symptoms of liver disease, including: Dark-colored pee, Light or clay-colored poop, Swelling from fluid in your belly or arms and legs, Yellowing of your skin and the whites of your eyes from jaundice.
  • #2 Hepatitis B Vaccine Guide | Immunization Info
    https://immunizationinfo.com/hepatitis-b/
    Hepatitis B is an infection with the hepatitis B virus (HBV) that causes liver inflammation and damage. Hepatitis B infections can cause long-term health problems like cirrhosis, liver cancer, liver failure, and death. […] Hepatitis B can be a short-term or long-term illness: Acute Hepatitis B: Mild illness that lasts a few weeks. The body usually gets rid of the virus on its own, but not always, and it can lead to chronic infections. Chronic Hepatitis B: Lifelong illness that occurs when the virus stays in the body forever. The risk decreases with age. Chronic infections occur in about 25-50% of children under 5 years old and it decreases to 6-10% of people who are infected after age 6. […] No. Around 70% of adults develop symptoms, but most children under 5 years old do not show symptoms of Hepatitis B. People who do not have symptoms are still very contagious.
  • #2 Hepatitis B Vaccine Guide | Immunization Info
    https://immunizationinfo.com/hepatitis-b/
    The symptoms of Hepatitis B include fever, fatigue, loss of appetite, nausea, vomiting, abdominal pain, dark urine, clay-colored bowel movements, joint pain, and jaundice (yellowing of skin and eyes). […] The average time for symptoms to appear is 90 days after exposure to the virus, but the incubation period ranges from 6 weeks to 6 months. […] Symptoms usually last for a few weeks, but some people experience symptoms for up to six months. The body usually gets rid of the virus, but not always. Some people develop chronic Hepatitis B infections, but they may not have any symptoms for as long as 20 or 30 years. […] About 15-25% of people with chronic Hepatitis B develop serious liver problems like cirrhosis (scarring of the liver) or liver cancer. […] Yes. Every year, about 1,800 people in the U.S. die from Hepatitis B-related liver disease.
  • #2 Hepatitis B: What It Is, Symptoms, Transmission & Treatment
    https://my.clevelandclinic.org/health/diseases/4246-hepatitis-b
    Acute and chronic hepatitis B may cause complications like: Acute liver failure. This is liver failure that happens very quickly. People with acute hepatitis B have an increased risk of acute liver failure. Chronic liver failure. Chronic hepatitis B can lead to liver failure that happens over time. Cirrhosis. Cirrhosis happens when scar tissue builds up in your liver. Your liver makes scar tissue when it repairs damage. The more damage, the more scar tissue. Hepatitis D. This is another type of hepatitis that you can get if you have hepatitis B. Liver cancer. Chronic hepatitis B is the leading cause of liver cancer. Reactivated hepatitis B. This is acute hepatitis B that comes back if you take immunosuppressants or stop the medication. […] Chronic hepatitis B symptoms can change over time. One way you can take care of yourself is to stay connected with your healthcare team.
  • #2 Hepatitis B Vaccine: Side Effects & Reactions | Carreras Medical Center
    https://www.toplinemd.com/carreras-medical-center/hepatitis-b-vaccine-side-effects-reactions/
    In terms of safety, the hepatitis B vaccine is exceptionally safe. As with any medication, there is a small risk of serious issues arising after vaccination. However, it is essential to note that the risk of developing hepatitis B and its potentially fatal consequences far outweigh the risks associated with the vaccine. […] The hepatitis B vaccine is a true game-changer in the world of preventive medicine. It provides at least 98 percent protection to infants, children, and adults who complete the recommended vaccination schedule before exposure to the virus. […] In conclusion, while the hepatitis B vaccine may cause some mild and short-lived side effects in rare cases, its safety and effectiveness make it a vital component of public health.
  • #2 Hepatitis-a/b-vaccine: Side Effects, Uses, Dosage, Interactions, Warnings
    https://www.rxlist.com/hepatitis-ab-vaccine/generic-drug.htm
    Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out. […] Results from clinical studies indicate that there is no association between hepatitis B vaccination and development of multiple sclerosis and that vaccination with hepatitis B vaccine does not appear to increase the short-term risk of relapse in multiple sclerosis.
  • #2 Your Child’s Vaccines: Hepatitis B Vaccine (HepB) (for Parents) | Nemours KidsHealth
    https://kidshealth.org/en/parents/hepb-vaccine.html
    The hepatitis B vaccine (HepB) protects against hepatitis B, a liver infection caused by the hepatitis B virus. People who get infected can have no symptoms, or they can have a mild illness that feels like the flu. Some can be sicker with fever, nausea, vomiting, and jaundice that lasts for a few weeks. […] Side effects usually are mild, and can include a low fever, headache, tiredness, loss of appetite, and soreness or redness at the injection site. As with any vaccine, there is a small risk of fainting, and a very small chance of an allergic reaction. […] The HepB vaccine usually creates long-term immunity. Most infants who get the HepB series are protected from hepatitis B infection beyond childhood, into their adult years. Protecting from hepatitis B infection also decreases risk for cirrhosis of the liver, chronic liver disease, and liver cancer. […] The HepB vaccine contains a killed (inactivated) virus, so it can’t cause hepatitis.
  • #2 Hepatitis B vaccine | Vaccinations and Immunisations | Forums
    https://patient.info/forums/discuss/hepatitis-b-vaccine-545001
    The vaccine used these days is created by altering yeast to carry hepatitis antigens, so there is no actual hepatitis viruses dead or alive in the vaccine. You will need to complete the course before re-testing, there’s simply no point. Let your wife rest and recover, do what you can to help her, she will recover more quickly that way. Hope she’s better soon and your symptoms go quickly.