Materiały źródłowe

• #1 Hepatitis b vaccine (intramuscular route) – Mayo Clinic

  https://www.mayoclinic.org/drugs-supplements/hepatitis-b-vaccine-intramuscular-route/description/drg-20068700

  Hepatitis B vaccine recombinant is used to prevent infection by the hepatitis B virus. The vaccine works by causing your body to produce its own protection (antibodies) against the disease. […] Immunization against hepatitis B disease is recommended for all newborn babies, infants, children, and adolescents up to 19 years of age. It is also recommended for adults who live in areas that have a high rate of hepatitis B disease or who may be at increased risk of infection from hepatitis B virus. […] This vaccine is available only from your doctor or other authorized health care professional. […] A nurse or other trained health professional will give you this vaccine. This vaccine is given as a shot into one of your muscles. If you have bleeding problems such as hemophilia, the vaccine may be given as a shot under your skin.

• #2 Hepatitis B Vaccine – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK554400/

  The hepatitis B vaccine is a medication used to prevent hepatitis B infection, which can lead to chronic liver failure and hepatocellular carcinoma. This activity reviews the indications, actions, and contraindications of the hepatitis B vaccine as a valuable agent in preventing hepatitis B infection. […] Identify the administration regimens of the hepatitis B vaccine. […] Evaluate the monitoring for patients receiving the hepatitis B vaccine, including any toxicity. […] Outline the importance of improving care coordination amongst the healthcare team to enhance care delivery for patients receiving the hepatitis B vaccine. […] The vaccine is a non-infectious subunit of the virus, which leads to an active immunity. […] Intramuscular injection is the preferred administration method.

• #3

  https://historyofvaccines.org/diseases/hepatitis-and-hepatitis-b/

  The FDA has licensed several hepatitis B vaccines for use in the United States, including several combination vaccines. It has been part of the routine childhood immunization schedule since 1994. […] The vaccine contains no live virus and is safe even for people with reduced immune function.

• #4 Hepatitis B Vaccine Patient Drug Record | NIH

  https://clinicalinfo.hiv.gov/en/drugs/hepatitis-b-vaccine/patient

  A hepatitis B vaccine prevents hepatitis B virus infection (HBV). Engerix-B, Heplisav-B, and Recombivax HB (all brand names) are examples of hepatitis B vaccines approved by the U.S. Food and Drug Administration (FDA). Engerix-B and Recombivax HB are both approved for use in people of all ages. Heplisav-B is approved for use in adults 18 years of age and older. […] Before receiving a hepatitis B vaccine, tell your health care provider: If you are allergic to yeast or any other ingredient in a hepatitis B vaccine; latex; or any medicines. Tell your health care provider if you have ever had any reactions to a previous dose of a hepatitis B vaccine. […] A health care provider gives the hepatitis B vaccine. The vaccine is given as a shot injected into a muscle, usually in the arm for adults and children older than 1 year and in the thigh for infants and children younger than 1 year. Vaccination with a hepatitis B vaccine is usually given as a series of injections over a period of time, depending on the specific brand of the vaccine.

• #5 Hepatitis B Vaccine Administration | Hepatitis B | CDC

  https://www.cdc.gov/hepatitis-b/hcp/vaccine-administration/index.html

  The Advisory Committee on Immunization Practices (ACIP) recommends hepatitis B (HepB) vaccination among all infants at birth, unvaccinated children younger than 19 years of age, adults aged 19-59 years, and adults aged 60 years and older with risk factors for hepatitis B or without identified risk factors but seeking protection. […] ACIP recommends that the following people should receive hepatitis B (HepB) vaccination: All infants, unvaccinated children younger than 19 years of age, adults 19-59 years, adults 60 years and older with risk factors for hepatitis B. […] Vaccinate susceptible persons without documentation of a completed hepatitis B vaccination series; testing should not be a barrier to vaccination. […] Providers should vaccinate adult hemodialysis patients needing HepB vaccination with high-dose (40ug) Engerix-B or Recombivax HB.

• #6 Hepatitis B Vaccine (Interim) VIS | Vaccines & Immunizations | CDC

  https://www.cdc.gov/vaccines/hcp/current-vis/hepatitis-b.html

  Hepatitis B vaccine can prevent hepatitis B. Hepatitis B is a liver disease that can cause mild illness lasting a few weeks, or it can lead to a serious, lifelong illness. […] Most people who are vaccinated with hepatitis B vaccine are immune for life. […] Hepatitis B vaccine is usually given as 2, 3, or 4 shots. […] The birth dose of hepatitis B vaccine is an important part of preventing long-term illness in infants and the spread of hepatitis B in the United States. […] Hepatitis B vaccination is recommended for adults 60 years or older at increased risk of exposure to hepatitis B who were not vaccinated previously. […] Pregnant or breastfeeding women who were not vaccinated previously should be vaccinated. Pregnancy or breastfeeding are not reasons to avoid hepatitis B vaccination.

• #7 Hepatitis B Vaccine – Drugs and Lactation Database (LactMed®) – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK500943/

  The Centers for Disease Control and Prevention and several health professional organizations state that vaccines given to a nursing mother do not affect the safety of breastfeeding infants and that breastfeeding is not a contraindication to the hepatitis B vaccine. Hepatitis B vaccine is recommended along with hepatitis B immune globulin to be given by injection to infants of mothers who are positive for hepatitis B surface antigen. No differences exist in infection rates between breastfed and formula-fed infants born to hepatitis B-infected women, as long as the infant receives these preventative measures at birth. […] Breastfeeding improves the infants response to hepatitis B immunization. […] Mothers with hepatitis B are encouraged to breastfeed their infants after their infants receive these preventative measures.

• #8 Hepatitis B Vaccine Administration | Hepatitis B | CDC

  https://www.cdc.gov/hepatitis-b/hcp/vaccine-administration/index.html

  Providers should vaccinate pregnant patients needing HepB vaccination with Engerix-B, Heplisav-B, Recombivax HB, or Twinrix. […] Scientific evidence overwhelmingly supports the safety of HepB vaccines. […] The most frequently reported adverse event associated with HepB vaccination is injection site soreness. […] Clinicians should administer the vaccine intramuscularly into the anterolateral aspect of the thigh or the deltoid muscle of the upper arm, depending on the person’s age. […] Clinicians can administer HepB vaccine concurrently with other vaccines to children and adults. There is no evidence that coadministration reduces the vaccine response or effectiveness.

• #9 Hepatitis B Vaccine (Interim) VIS | Vaccines & Immunizations | CDC

  https://www.cdc.gov/vaccines/hcp/current-vis/hepatitis-b.html

  Hepatitis B vaccine can prevent hepatitis B. Hepatitis B is a liver disease that can cause mild illness lasting a few weeks, or it can lead to a serious, lifelong illness. […] Most people who are vaccinated with hepatitis B vaccine are immune for life. […] Hepatitis B vaccine is usually given as 2, 3, or 4 shots. […] The birth dose of hepatitis B vaccine is an important part of preventing long-term illness in infants and the spread of hepatitis B in the United States. […] Hepatitis B vaccination is recommended for adults 60 years or older at increased risk of exposure to hepatitis B who were not vaccinated previously. […] Pregnant or breastfeeding women who were not vaccinated previously should be vaccinated. Pregnancy or breastfeeding are not reasons to avoid hepatitis B vaccination.

• #10 Hepatitis B Vaccine: Side Effects, Uses, Dosage, Interactions, Warnings

  https://www.rxlist.com/hepatitis_b_vaccine/generic-drug.htm

  Hepatitis B Vaccine is indicated for prevention of infection caused by all known subtypes of hepatitis B virus. Recombivax HB is approved for use in individuals of all ages. […] Dosages of Hepatitis B Vaccine: Intramuscular suspension (adult formulation) 10 mcg/ml (Recombivax HB), 20 mcg/ml (Engerix B), 40 mcg/ml (Recombivax HB [dialysis formulation]). […] Adult Dosage: Engerix B: 1 mL (20 mcg) intramuscularly at 0, 1, and 6 months; Recombivax HB: 1 mL (10 mcg) intramuscularly at 0, 1, and 6 months. […] Routine immunization against hepatitis B; also protects against hepatitis D which always occurs in the presence of hepatitis B. […] Administer intramuscularly in the deltoid muscle. […] Pediatric: Administer in deltoid muscle for older children and adolescents; anterolateral thigh preferred for neonates/infants/small children.

• #11 Your Child’s Vaccines: Hepatitis B Vaccine (HepB) (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/hepb-vaccine.html

  The hepatitis B vaccine (HepB) protects against hepatitis B, a liver infection caused by the hepatitis B virus. […] Kids usually get the hepatitis B vaccine (HepB) as a series of 3 shots: shortly after birth, at 12 months of age, at 618 months of age. […] If a newborn’s mother carries the hepatitis B virus in her blood, the baby must get the vaccine within 12 hours after birth. […] Anyone under age 60 should get the vaccine series at any time if they missed it as a baby. […] Some kids may need to get vaccinated again later in life. […] People who dont know they’re infected can spread the hepatitis B virus. […] The HepB vaccine usually creates long-term immunity. […] Protecting from hepatitis B infection also decreases risk for cirrhosis of the liver, chronic liver disease, and liver cancer.

• #12 HBV (hepatitis B) | OSF HealthCare

  https://www.osfhealthcare.org/treatments/hbv

  Hepatitis B vaccine can prevent hepatitis B. Hepatitis B is a liver disease that can cause mild illness lasting a few weeks, or it can lead to a serious, lifelong illness. Most people who are vaccinated with hepatitis B vaccine are immune for life. Hepatitis B vaccine is usually given as 2, 3, or 4 shots. Infants should get their first dose of hepatitis B vaccine at birth and will usually complete the series at 618 months of age. The birth dose of hepatitis B vaccine is an important part of preventing long-term illness in infants and the spread of hepatitis B in the United States. Anyone 59 years of age or younger who has not yet gotten the vaccine should be vaccinated. Hepatitis B vaccination is recommended for adults 60 years or older at increased risk of exposure to hepatitis B who were not vaccinated previously. Adults 60 years or older who are not at increased risk and were not vaccinated in the past may also be vaccinated. Hepatitis B vaccine may be given as a stand-alone vaccine, or as part of a combination vaccine (a type of vaccine that combines more than one vaccine together into one shot). Hepatitis B vaccine may be given at the same time as other vaccines. Pregnant or breastfeeding people should be vaccinated if they are at risk for getting hepatitis B. Pregnancy or breastfeeding are not reasons to avoid hepatitis B vaccination. People with minor illnesses, such as a cold, may be vaccinated. People who are moderately or severely ill should usually wait until they recover before getting hepatitis B vaccine. Your health care provider can give you more information. Soreness where the shot is given, fever, headache, and fatigue (feeling tired) can happen after hepatitis B vaccination. An allergic reaction could occur after the vaccinated person leaves the clinic. Adverse reactions should be reported to the Vaccine Adverse Event Reporting System (VAERS).

• #13 Hepatitis B Vaccine: Side Effects, Uses, Dosage, Interactions, Warnings

  https://www.rxlist.com/hepatitis_b_vaccine/generic-drug.htm

  Hepatitis B Vaccine is indicated for prevention of infection caused by all known subtypes of hepatitis B virus. Recombivax HB is approved for use in individuals of all ages. […] Dosages of Hepatitis B Vaccine: Intramuscular suspension (adult formulation) 10 mcg/ml (Recombivax HB), 20 mcg/ml (Engerix B), 40 mcg/ml (Recombivax HB [dialysis formulation]). […] Adult Dosage: Engerix B: 1 mL (20 mcg) intramuscularly at 0, 1, and 6 months; Recombivax HB: 1 mL (10 mcg) intramuscularly at 0, 1, and 6 months. […] Routine immunization against hepatitis B; also protects against hepatitis D which always occurs in the presence of hepatitis B. […] Administer intramuscularly in the deltoid muscle. […] Pediatric: Administer in deltoid muscle for older children and adolescents; anterolateral thigh preferred for neonates/infants/small children.

• #14 Hepatitis B Vaccine Administration | Hepatitis B | CDC

  https://www.cdc.gov/hepatitis-b/hcp/vaccine-administration/index.html

  The Advisory Committee on Immunization Practices (ACIP) recommends hepatitis B (HepB) vaccination among all infants at birth, unvaccinated children younger than 19 years of age, adults aged 19-59 years, and adults aged 60 years and older with risk factors for hepatitis B or without identified risk factors but seeking protection. […] ACIP recommends that the following people should receive hepatitis B (HepB) vaccination: All infants, unvaccinated children younger than 19 years of age, adults 19-59 years, adults 60 years and older with risk factors for hepatitis B. […] Vaccinate susceptible persons without documentation of a completed hepatitis B vaccination series; testing should not be a barrier to vaccination. […] Providers should vaccinate adult hemodialysis patients needing HepB vaccination with high-dose (40ug) Engerix-B or Recombivax HB.

• #15 Hepatitis B Vaccine Administration | Hepatitis B | CDC

  https://www.cdc.gov/hepatitis-b/hcp/vaccine-administration/index.html

  Providers should vaccinate pregnant patients needing HepB vaccination with Engerix-B, Heplisav-B, Recombivax HB, or Twinrix. […] Scientific evidence overwhelmingly supports the safety of HepB vaccines. […] The most frequently reported adverse event associated with HepB vaccination is injection site soreness. […] Clinicians should administer the vaccine intramuscularly into the anterolateral aspect of the thigh or the deltoid muscle of the upper arm, depending on the person’s age. […] Clinicians can administer HepB vaccine concurrently with other vaccines to children and adults. There is no evidence that coadministration reduces the vaccine response or effectiveness.

• #16 Hepatitis B Vaccine: Side Effects, Uses, Dosage, Interactions, Warnings

  https://www.rxlist.com/hepatitis_b_vaccine/generic-drug.htm

  Hepatitis B Vaccine is indicated for prevention of infection caused by all known subtypes of hepatitis B virus. Recombivax HB is approved for use in individuals of all ages. […] Dosages of Hepatitis B Vaccine: Intramuscular suspension (adult formulation) 10 mcg/ml (Recombivax HB), 20 mcg/ml (Engerix B), 40 mcg/ml (Recombivax HB [dialysis formulation]). […] Adult Dosage: Engerix B: 1 mL (20 mcg) intramuscularly at 0, 1, and 6 months; Recombivax HB: 1 mL (10 mcg) intramuscularly at 0, 1, and 6 months. […] Routine immunization against hepatitis B; also protects against hepatitis D which always occurs in the presence of hepatitis B. […] Administer intramuscularly in the deltoid muscle. […] Pediatric: Administer in deltoid muscle for older children and adolescents; anterolateral thigh preferred for neonates/infants/small children.

• #17 Dosing and Administration Schedule for RECOMBIVAX HB® [Hepatitis B Vaccine (Recombinant)]

  https://www.merckvaccines.com/recombivax-hb/dosage-administration/

  Infants weighing 2000 g born to HBsAg positive or HBsAg unknown mothers should receive vaccine and hepatitis B immune globulin (HBIG) in accordance with ACIP recommendations if HBsAg status cannot be determined. […] Vaccination with RECOMBIVAX HB may not protect all individuals. […] In healthy infants and children (up to 10 years of age), injection site reactions and systemic adverse reactions were reported following 0.2% and 10.4% of the injections, respectively. […] The deltoid muscle is the preferred site for intramuscular injection for adults, adolescents, and children 1 year of age and older whose deltoid is large enough for intramuscular injection. […] The anterolateral aspect of the thigh is the preferred site for intramuscular injection for infants younger than 1 year of age.

• #18 Dosing and Administration Schedule for RECOMBIVAX HB® [Hepatitis B Vaccine (Recombinant)]

  https://www.merckvaccines.com/recombivax-hb/dosage-administration/

  Infants weighing 2000 g born to HBsAg positive or HBsAg unknown mothers should receive vaccine and hepatitis B immune globulin (HBIG) in accordance with ACIP recommendations if HBsAg status cannot be determined. […] Vaccination with RECOMBIVAX HB may not protect all individuals. […] In healthy infants and children (up to 10 years of age), injection site reactions and systemic adverse reactions were reported following 0.2% and 10.4% of the injections, respectively. […] The deltoid muscle is the preferred site for intramuscular injection for adults, adolescents, and children 1 year of age and older whose deltoid is large enough for intramuscular injection. […] The anterolateral aspect of the thigh is the preferred site for intramuscular injection for infants younger than 1 year of age.

• #19 Dosing and Administration Schedule for RECOMBIVAX HB® [Hepatitis B Vaccine (Recombinant)]

  https://www.merckvaccines.com/recombivax-hb/dosage-administration/

  RECOMBIVAX HB should not be administered in the gluteal region, as injections given in the buttocks have resulted in lower seroconversion rates than expected. […] Predialysis and dialysis adult patients respond less well to hepatitis B vaccines than do healthy individuals; however, vaccination of adult patients early in the course of their renal disease produces higher seroconversion rates than vaccination after dialysis has been initiated. […] Data are not available to assess the effects of RECOMBIVAX HB on the breastfed infant or on milk productions/excretion.

• #20 Hepatitis B (HepB) Vaccine – Infectious Diseases – MSD Manual Professional Edition

  https://www.msdmanuals.com/professional/infectious-diseases/immunization/hepatitis-b-hepb-vaccine

  The hepatitis B vaccine is 80 to 100% effective in preventing infection or clinical hepatitis B in people who complete the vaccine series. […] HepB vaccine is a routine childhood vaccination. […] HepB vaccine also is indicated for all adults aged 19 through 59 years who have not been previously vaccinated. […] Adults age 60 years or older without known risk factors for hepatitis B virus infection may receive a HepB vaccine series. […] The main contraindication for hepatitis B vaccine is a severe allergic reaction after previous dose or to baker’s yeast or any vaccine component. […] The main precaution with HepB vaccine is moderate or severe illness with or without a fever (vaccination is postponed until the illness resolves). […] The dose for Engerix-B and Recombivax HB is 0.5 mL IM up to age 20 years or 1 mL IM for adults.

• #21 Hepatitis B Vaccine (Interim) VIS | Vaccines & Immunizations | CDC

  https://www.cdc.gov/vaccines/hcp/current-vis/hepatitis-b.html

  Hepatitis B vaccine can prevent hepatitis B. Hepatitis B is a liver disease that can cause mild illness lasting a few weeks, or it can lead to a serious, lifelong illness. […] Most people who are vaccinated with hepatitis B vaccine are immune for life. […] Hepatitis B vaccine is usually given as 2, 3, or 4 shots. […] The birth dose of hepatitis B vaccine is an important part of preventing long-term illness in infants and the spread of hepatitis B in the United States. […] Hepatitis B vaccination is recommended for adults 60 years or older at increased risk of exposure to hepatitis B who were not vaccinated previously. […] Pregnant or breastfeeding women who were not vaccinated previously should be vaccinated. Pregnancy or breastfeeding are not reasons to avoid hepatitis B vaccination.

• #22 Hepatitis B Vaccine – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK554400/

  After completing the 3-vaccination series, patients may receive a blood test after 1 to 4 months to determine the immune response, which is defined as an anti-hepatitis B surface antigen (anti-Hbs) antibody level exceeding 100mIU/mL. […] All persons receiving the vaccine should remain under observation for at least 15 minutes following its administration for syncope or signs of anaphylaxis. […] Nurses should always verify the patient’s vaccination status regarding hepatitis B (as well as other vaccines) and report their findings to the clinician. […] All team members can increase the vaccination rate of their patients by encouraging all staff to become trained in the assessment of vaccination histories and any pertinent staff in administering the vaccine.

• #23 Schedule Hepatitis B Vaccine | Walgreens

  https://www.walgreens.com/topic/pharmacy/scheduler/hepatitis-b-vaccine_34.jsp

  Schedule your vaccine today. […] The hepatitis B vaccine is the best way to prevent infection. It is a series of 2, 3 or 4 shots usually given over a 612-month period. It is given by an injection into the arm muscle of adolescents and adults and thigh muscle of infants and young children. Estimates of long-term protection for those getting the full vaccination series suggest that protection from hepatitis B could last for up to 20 or 30 years and possibly for life. […] The hepatitis B vaccine is recommended for all infants, all children or adolescents younger than 19 years of age who have not been vaccinated, all adults ages 19 through 59 years, and adults ages 60 years or older with risk factors for hepatitis B infection. […] Pregnant people who need protection from hepatitis B may be vaccinated but should check with their doctor first.

• #24 Dosing and Administration Schedule for RECOMBIVAX HB® [Hepatitis B Vaccine (Recombinant)]

  https://www.merckvaccines.com/recombivax-hb/dosage-administration/

  RECOMBIVAX HB should not be administered in the gluteal region, as injections given in the buttocks have resulted in lower seroconversion rates than expected. […] Predialysis and dialysis adult patients respond less well to hepatitis B vaccines than do healthy individuals; however, vaccination of adult patients early in the course of their renal disease produces higher seroconversion rates than vaccination after dialysis has been initiated. […] Data are not available to assess the effects of RECOMBIVAX HB on the breastfed infant or on milk productions/excretion.

• #25 Hepatitis B (HepB) Vaccine – Infectious Diseases – MSD Manual Professional Edition

  https://www.msdmanuals.com/professional/infectious-diseases/immunization/hepatitis-b-hepb-vaccine

  The hepatitis B vaccine is 80 to 100% effective in preventing infection or clinical hepatitis B in people who complete the vaccine series. […] HepB vaccine is a routine childhood vaccination. […] HepB vaccine also is indicated for all adults aged 19 through 59 years who have not been previously vaccinated. […] Adults age 60 years or older without known risk factors for hepatitis B virus infection may receive a HepB vaccine series. […] The main contraindication for hepatitis B vaccine is a severe allergic reaction after previous dose or to baker’s yeast or any vaccine component. […] The main precaution with HepB vaccine is moderate or severe illness with or without a fever (vaccination is postponed until the illness resolves). […] The dose for Engerix-B and Recombivax HB is 0.5 mL IM up to age 20 years or 1 mL IM for adults.

• #26 Official Site for RECOMBIVAX HB® [Hepatitis B Vaccine (Recombinant)]

  https://www.merckvaccines.com/recombivax-hb/

  RECOMBIVAX HB is indicated for prevention of infection caused by all known subtypes of hepatitis B virus. […] RECOMBIVAX HB is approved for use in individuals of all ages. […] RECOMBIVAX HB Dialysis Formulation is approved for use in adult predialysis and dialysis patients 18 years of age and older. […] Do not administer RECOMBIVAX HB to individuals with a history of severe allergic or hypersensitivity reactions (eg, anaphylaxis) after a previous dose of any hepatitis B-containing vaccine or to any component of RECOMBIVAX HB, including yeast. […] Apnea following intramuscular vaccination has been observed in some infants born prematurely. […] Hepatitis B vaccination should be delayed until 1 month of age or hospital discharge in infants weighing 2000 g if the mother is documented to be HBsAg negative at the time of the infants birth.

• #27 Hepatitis B (HepB) Vaccine – Infectious Diseases – MSD Manual Professional Edition

  https://www.msdmanuals.com/professional/infectious-diseases/immunization/hepatitis-b-hepb-vaccine

  The hepatitis B vaccine is 80 to 100% effective in preventing infection or clinical hepatitis B in people who complete the vaccine series. […] HepB vaccine is a routine childhood vaccination. […] HepB vaccine also is indicated for all adults aged 19 through 59 years who have not been previously vaccinated. […] Adults age 60 years or older without known risk factors for hepatitis B virus infection may receive a HepB vaccine series. […] The main contraindication for hepatitis B vaccine is a severe allergic reaction after previous dose or to baker’s yeast or any vaccine component. […] The main precaution with HepB vaccine is moderate or severe illness with or without a fever (vaccination is postponed until the illness resolves). […] The dose for Engerix-B and Recombivax HB is 0.5 mL IM up to age 20 years or 1 mL IM for adults.

• #28 Official Site for RECOMBIVAX HB® [Hepatitis B Vaccine (Recombinant)]

  https://www.merckvaccines.com/recombivax-hb/

  RECOMBIVAX HB is indicated for prevention of infection caused by all known subtypes of hepatitis B virus. […] RECOMBIVAX HB is approved for use in individuals of all ages. […] RECOMBIVAX HB Dialysis Formulation is approved for use in adult predialysis and dialysis patients 18 years of age and older. […] Do not administer RECOMBIVAX HB to individuals with a history of severe allergic or hypersensitivity reactions (eg, anaphylaxis) after a previous dose of any hepatitis B-containing vaccine or to any component of RECOMBIVAX HB, including yeast. […] Apnea following intramuscular vaccination has been observed in some infants born prematurely. […] Hepatitis B vaccination should be delayed until 1 month of age or hospital discharge in infants weighing 2000 g if the mother is documented to be HBsAg negative at the time of the infants birth.

• #29 Hepatitis B Vaccine Administration | Hepatitis B | CDC

  https://www.cdc.gov/hepatitis-b/hcp/vaccine-administration/index.html

  Providers should vaccinate pregnant patients needing HepB vaccination with Engerix-B, Heplisav-B, Recombivax HB, or Twinrix. […] Scientific evidence overwhelmingly supports the safety of HepB vaccines. […] The most frequently reported adverse event associated with HepB vaccination is injection site soreness. […] Clinicians should administer the vaccine intramuscularly into the anterolateral aspect of the thigh or the deltoid muscle of the upper arm, depending on the person’s age. […] Clinicians can administer HepB vaccine concurrently with other vaccines to children and adults. There is no evidence that coadministration reduces the vaccine response or effectiveness.

• #30 Hepatitis B Vaccine (Interim) VIS | Vaccines & Immunizations | CDC

  https://www.cdc.gov/vaccines/hcp/current-vis/hepatitis-b.html

  Risks of a vaccine reaction include soreness where the shot is given, fever, headache, and fatigue (feeling tired) can happen after hepatitis B vaccination. […] An allergic reaction could occur after the vaccinated person leaves the clinic. If you see signs of a severe allergic reaction (hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, or weakness), call 9-1-1 and get the person to the nearest hospital.

• #31 Hepatitis B – immunisation | Better Health Channel

  https://www.betterhealth.vic.gov.au/health/healthyliving/hepatitis-b-immunisation

  Protection against hepatitis B is available free of charge under the National Immunisation Program Schedule. […] In Victoria, vaccination against hepatitis B is free for all babies and children including: babies at birth vaccinate with hepatitis B vaccine as soon as possible after birth. […] The current Australian immunisation program provides free hepatitis B vaccine to protect all children against the hepatitis B virus. […] A full course of hepatitis B injections must be given for a child to be protected. […] Serious side effects or allergic reactions to the vaccines are very rare. […] If you are concerned about your or your child’s reaction to any vaccine, see your doctor immediately. […] If you think you have been exposed to hepatitis B, see a doctor immediately. Your doctor can give you treatment that, in some instances, can greatly reduce your risk of infection with hepatitis B.

• #32 Hepatitis B Vaccine: MedlinePlus Drug InformationLock

  https://medlineplus.gov/druginfo/meds/a607014.html

  An allergic reaction could occur after the vaccinated person leaves the clinic. If you see signs of a severe allergic reaction (hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, or weakness), call 9-1-1 and get the person to the nearest hospital. […] The National Vaccine Injury Compensation Program (VICP) is a federal program that was created to compensate people who may have been injured by certain vaccines.

• #33 Hepatitis B vaccine | Nursing Times

  https://www.nursingtimes.net/medicine-management/hepatitis-b-vaccine-08-10-2004/

  – Additional doses may be required for individuals with a suppressed immune system. […] – Correct cold chain vaccine storage should be ensured. […] – The injection site batch number and expiry date should be recorded in the patient record. […] – Nurses should refer to manufacturers summary of product characteristics and to appropriate local guidelines.

• #34 Hepatitis B vaccine | Nursing Times

  https://www.nursingtimes.net/medicine-management/hepatitis-b-vaccine-08-10-2004/

  – Additional doses may be required for individuals with a suppressed immune system. […] – Correct cold chain vaccine storage should be ensured. […] – The injection site batch number and expiry date should be recorded in the patient record. […] – Nurses should refer to manufacturers summary of product characteristics and to appropriate local guidelines.

• #35 Hepatitis B Vaccine for Newborns | Free NURSING.com Courses

  https://nursing.com/lesson/hepatitis-b-vaccine-for-newborns

  Hepatitis B vaccine […] Recommended by CDC to be given in first 12 hours of life […] IM injection […] If mother already has Hepatitis B, then Hep B immune globulin also needs to be given […] The Hepatitis B vaccine (Hb vaccine or HBV) is recommended by the CDC to be given within the first 12 hours of life. It is administered via an intramuscular (IM) injection […] If the mother already has Hepatitis B, Hep B immune globulin (HBIG) also needs to be administered to the infant […] When giving the IM injection, target the lateral side of the middle third of the vastus lateralis muscle […] Proper documentation is essential. This typically includes documenting in the hospital chart and providing a record card to the parents for their reference […] These nursing considerations are crucial for the effective care and prevention of Hepatitis B in both newborns and individuals at risk. Following these guidelines ensures safe and efficient management of the condition. […] Educate importance and need […] If they want to refuse; follow hospital policy and document appropriately.

• #36 Hepatitis B Vaccine: Side Effects, Uses, Dosage, Interactions, Warnings

  https://www.rxlist.com/hepatitis_b_vaccine/generic-drug.htm

  Hepatitis B Vaccine is indicated for prevention of infection caused by all known subtypes of hepatitis B virus. Recombivax HB is approved for use in individuals of all ages. […] Dosages of Hepatitis B Vaccine: Intramuscular suspension (adult formulation) 10 mcg/ml (Recombivax HB), 20 mcg/ml (Engerix B), 40 mcg/ml (Recombivax HB [dialysis formulation]). […] Adult Dosage: Engerix B: 1 mL (20 mcg) intramuscularly at 0, 1, and 6 months; Recombivax HB: 1 mL (10 mcg) intramuscularly at 0, 1, and 6 months. […] Routine immunization against hepatitis B; also protects against hepatitis D which always occurs in the presence of hepatitis B. […] Administer intramuscularly in the deltoid muscle. […] Pediatric: Administer in deltoid muscle for older children and adolescents; anterolateral thigh preferred for neonates/infants/small children.

• #37 Hepatitis B Vaccine – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK554400/

  After completing the 3-vaccination series, patients may receive a blood test after 1 to 4 months to determine the immune response, which is defined as an anti-hepatitis B surface antigen (anti-Hbs) antibody level exceeding 100mIU/mL. […] All persons receiving the vaccine should remain under observation for at least 15 minutes following its administration for syncope or signs of anaphylaxis. […] Nurses should always verify the patient’s vaccination status regarding hepatitis B (as well as other vaccines) and report their findings to the clinician. […] All team members can increase the vaccination rate of their patients by encouraging all staff to become trained in the assessment of vaccination histories and any pertinent staff in administering the vaccine.

• #38 Hepatitis B Vaccine for Newborns | Free NURSING.com Courses

  https://nursing.com/lesson/hepatitis-b-vaccine-for-newborns

  Hepatitis B vaccine […] Recommended by CDC to be given in first 12 hours of life […] IM injection […] If mother already has Hepatitis B, then Hep B immune globulin also needs to be given […] The Hepatitis B vaccine (Hb vaccine or HBV) is recommended by the CDC to be given within the first 12 hours of life. It is administered via an intramuscular (IM) injection […] If the mother already has Hepatitis B, Hep B immune globulin (HBIG) also needs to be administered to the infant […] When giving the IM injection, target the lateral side of the middle third of the vastus lateralis muscle […] Proper documentation is essential. This typically includes documenting in the hospital chart and providing a record card to the parents for their reference […] These nursing considerations are crucial for the effective care and prevention of Hepatitis B in both newborns and individuals at risk. Following these guidelines ensures safe and efficient management of the condition. […] Educate importance and need […] If they want to refuse; follow hospital policy and document appropriately.

• #39 Hepatitis B vaccine – what you need to know Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/special-topic/hepatitis-b-vaccine-what-you-need-to-know

  Hepatitis B vaccine can prevent hepatitis B. Hepatitis B is a liver disease that can cause mild illness lasting a few weeks, or it can lead to a serious, lifelong illness. […] Most people who are vaccinated with hepatitis B vaccine are immune for life. […] Hepatitis B vaccination is recommended for adults 60 years or older at increased risk of exposure to hepatitis B who were not vaccinated previously. Adults 60 years or older who are not at increased risk and were not vaccinated in the past may also be vaccinated. […] Pregnant or breastfeeding women who were not vaccinated previously should be vaccinated. Pregnancy or breastfeeding are not reasons to avoid hepatitis B vaccination. […] Your health care provider can give you more information. […] An allergic reaction could occur after the vaccinated person leaves the clinic. If you see signs of a severe allergic reaction (hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, or weakness), call 9-1-1 and get the person to the nearest hospital. […] Adverse reactions should be reported to the Vaccine Adverse Event Reporting System (VAERS). Your health care provider will usually file this report, or you can do it yourself.

• #40 Hepatitis B Vaccine: Care Instructions | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.hepatitis-b-vaccine-care-instructions.zc1827

  The hepatitis B vaccine protects against infection with the hepatitis B virus. A hepatitis B infection can damage the liver and lead to liver cancer. […] The vaccine is given to adults in three doses. You receive the shots in your upper arm. You should get the second shot at least 1 month after the first one. The third shot is most often given about 6 months after the first one. After you get all three doses, you will be protected for at least 15 years. This vaccine is safe for women who are pregnant or breastfeeding. […] Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It’s also a good idea to know your test results and keep a list of the medicines you take. […] Call your doctor now or seek immediate medical care if: You have symptoms of an allergic reaction, such as: A rash or hives (raised, red areas on the skin). Itching. Swelling. Mild belly pain or nausea. You have a high fever. […] Watch closely for changes in your health, and be sure to contact your doctor if you have any problems.

• #41 Hepatitis B: Nursing Diagnosis & Interventions | Nurse.com

  https://www.nurse.com/clinical-guides/hepatitis-b/?srsltid=AfmBOooL5zy1njN3SmTlFQ-a7-U9Vd8kAw9fIMPseMHPJm8Imk_AxfCw

  The best treatment for hepatitis B is prevention through the hepatitis B vaccine. […] The individual with hepatitis B and their household should be vaccinated for hepatitis B. Education should include proper preventative practices to avoid the transmission of disease to others. […] Nursing interventions will vary among individuals. Some of the most common nursing interventions include: Educate individual on ways to conserve energy. […] The individual should also be aware of the importance of follow-up treatments. […] Certain medications such as acetaminophen (Tylenol) should be avoided due to the potential for liver toxicity. The individual should be educated not to take any medication or drugs unless approved by their healthcare provider. Alcohol should also be avoided.

• #42 Hepatitis B Vaccine: Care Instructions | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.hepatitis-b-vaccine-care-instructions.zc1827

  The hepatitis B vaccine protects against infection with the hepatitis B virus. A hepatitis B infection can damage the liver and lead to liver cancer. […] The vaccine is given to adults in three doses. You receive the shots in your upper arm. You should get the second shot at least 1 month after the first one. The third shot is most often given about 6 months after the first one. After you get all three doses, you will be protected for at least 15 years. This vaccine is safe for women who are pregnant or breastfeeding. […] Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It’s also a good idea to know your test results and keep a list of the medicines you take. […] Call your doctor now or seek immediate medical care if: You have symptoms of an allergic reaction, such as: A rash or hives (raised, red areas on the skin). Itching. Swelling. Mild belly pain or nausea. You have a high fever. […] Watch closely for changes in your health, and be sure to contact your doctor if you have any problems.

• #43 Hepatitis B Vaccine: Care Instructions | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.hepatitis-b-vaccine-care-instructions.zc1827

  The hepatitis B vaccine protects against infection with the hepatitis B virus. A hepatitis B infection can damage the liver and lead to liver cancer. […] The vaccine is given to adults in three doses. You receive the shots in your upper arm. You should get the second shot at least 1 month after the first one. The third shot is most often given about 6 months after the first one. After you get all three doses, you will be protected for at least 15 years. This vaccine is safe for women who are pregnant or breastfeeding. […] Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It’s also a good idea to know your test results and keep a list of the medicines you take. […] Call your doctor now or seek immediate medical care if: You have symptoms of an allergic reaction, such as: A rash or hives (raised, red areas on the skin). Itching. Swelling. Mild belly pain or nausea. You have a high fever. […] Watch closely for changes in your health, and be sure to contact your doctor if you have any problems.

• #44 Hepatitis B: Nursing Diagnosis & Interventions | Nurse.com

  https://www.nurse.com/clinical-guides/hepatitis-b/?srsltid=AfmBOooL5zy1njN3SmTlFQ-a7-U9Vd8kAw9fIMPseMHPJm8Imk_AxfCw

  The best treatment for hepatitis B is prevention through the hepatitis B vaccine. […] The individual with hepatitis B and their household should be vaccinated for hepatitis B. Education should include proper preventative practices to avoid the transmission of disease to others. […] Nursing interventions will vary among individuals. Some of the most common nursing interventions include: Educate individual on ways to conserve energy. […] The individual should also be aware of the importance of follow-up treatments. […] Certain medications such as acetaminophen (Tylenol) should be avoided due to the potential for liver toxicity. The individual should be educated not to take any medication or drugs unless approved by their healthcare provider. Alcohol should also be avoided.

• #45 Nurses need to help wipe out chronic hepatitis B, a disease borne by 300 million people – Hepatitis B Foundation

  https://www.hepb.org/blog/nurses-need-help-wipe-chronic-hepatitis-b-disease-borne-300-million-people/

  Nurses such as you and me yes, that means all nurses (and our welcomed health care counterparts) likely come across a patient or parent who declines vaccinations for themselves or their children. […] While every nurse may provide vaccine education at some point in a patients life, those in neonatal and maternal-newborn nursing have a greater responsibility with the hepatitis B vaccine. […] However, communicating those reasons to parents of our newborn patients takes a compassionate, strong and skillful approach. […] There are various clinical settings and times when nurses can educate new parents and those with children about how the hepatitis B vaccine works and why it is necessary. […] When addressing the highly recommended CDCs vaccine schedule with parents, the rule of thumb is letting them know to expect their child will get the hep B vaccine series starting at birth.

• #46 Nurses need to help wipe out chronic hepatitis B, a disease borne by 300 million people – Hepatitis B Foundation

  https://www.hepb.org/blog/nurses-need-help-wipe-chronic-hepatitis-b-disease-borne-300-million-people/

  First and foremost, determining the why in what is making the parent hesitant about or declining the hep B vaccine is vital when trying to help them understand the reason vaccination is strongly advised. […] Educating parents about complications that acquiring hepatitis B can have on the body can emphasize the vaccines purpose. […] Nurses need to use language that is concise and easy to understand. […] Nurses can let parents know hepatitis B is a virus that causes inflammation of the liver that damages and compromises its function, which can and often does lead to liver disease and ultimately cancer. […] Unlike a common bacterial infection that can quickly be treated with antibiotics, acquiring a hepatitis B infection can mean living with a chronic, life-long and potentially life-threatening illness.

• #47 Perinatal Hepatitis B: What Nurses need to Know | doh

  https://dchealth.dc.gov/page/perinatal-hepatitis-b-what-nurses-need-know

  What Nurses Need to Know About Hep B and Pregnancy […] As nurses, you have a vital role in perinatal hepatitis B prevention. Some of the latest recommendations for nursing care include: […] Review the maternal HBsAg (antigen) original test result for each maternal admission. If unknown, obtain a STAT order from admitting provider. If pregnant delivery parent is HBsAg (antigen) positive, alert the nursery personnel. Following your hospital infectious disease protocol for care of infant. Administer hepatitis B vaccine and hepatitis B immune globulin (HBIG) as indicated within 12 hours of birth. Educate the parent in hepatitis B and its prevention in a language appropriate for parent. […] Report the delivery to your Perinatal Hepatitis B Nurse Specialist.

• #48 Perinatal Hepatitis B: What Nurses need to Know | doh

  https://dchealth.dc.gov/page/perinatal-hepatitis-b-what-nurses-need-know

  What Nurses Need to Know About Hep B and Pregnancy […] As nurses, you have a vital role in perinatal hepatitis B prevention. Some of the latest recommendations for nursing care include: […] Review the maternal HBsAg (antigen) original test result for each maternal admission. If unknown, obtain a STAT order from admitting provider. If pregnant delivery parent is HBsAg (antigen) positive, alert the nursery personnel. Following your hospital infectious disease protocol for care of infant. Administer hepatitis B vaccine and hepatitis B immune globulin (HBIG) as indicated within 12 hours of birth. Educate the parent in hepatitis B and its prevention in a language appropriate for parent. […] Report the delivery to your Perinatal Hepatitis B Nurse Specialist.

• #49 Perinatal Hepatitis B: What Nurses need to Know | doh

  https://dchealth.dc.gov/page/perinatal-hepatitis-b-what-nurses-need-know

  What Nurses Need to Know About Hep B and Pregnancy […] As nurses, you have a vital role in perinatal hepatitis B prevention. Some of the latest recommendations for nursing care include: […] Review the maternal HBsAg (antigen) original test result for each maternal admission. If unknown, obtain a STAT order from admitting provider. If pregnant delivery parent is HBsAg (antigen) positive, alert the nursery personnel. Following your hospital infectious disease protocol for care of infant. Administer hepatitis B vaccine and hepatitis B immune globulin (HBIG) as indicated within 12 hours of birth. Educate the parent in hepatitis B and its prevention in a language appropriate for parent. […] Report the delivery to your Perinatal Hepatitis B Nurse Specialist.

• #50 Hepatitis B Vaccine Administration | Hepatitis B | CDC

  https://www.cdc.gov/hepatitis-b/hcp/vaccine-administration/index.html

  The Advisory Committee on Immunization Practices (ACIP) recommends hepatitis B (HepB) vaccination among all infants at birth, unvaccinated children younger than 19 years of age, adults aged 19-59 years, and adults aged 60 years and older with risk factors for hepatitis B or without identified risk factors but seeking protection. […] ACIP recommends that the following people should receive hepatitis B (HepB) vaccination: All infants, unvaccinated children younger than 19 years of age, adults 19-59 years, adults 60 years and older with risk factors for hepatitis B. […] Vaccinate susceptible persons without documentation of a completed hepatitis B vaccination series; testing should not be a barrier to vaccination. […] Providers should vaccinate adult hemodialysis patients needing HepB vaccination with high-dose (40ug) Engerix-B or Recombivax HB.

• #51 Hepatitis B Virus Vaccine Intramuscular: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing – WebMD

  https://www.webmd.com/drugs/2/drug-63870/hepatitis-b-virus-vaccine-intramuscular/details

  Older adults and people on dialysis may not respond as well to the vaccine. […] During pregnancy, this vaccine should be used only when clearly needed. […] It is unknown if this vaccine passes into breast milk. Consult your health care professional before breastfeeding. […] Keep vaccine records for yourself and your children and provide them to the health care professionals to prevent unnecessary re-vaccinations. […] It is important that you get each vaccination as scheduled.

• #52 Heplisav-B vs Standard Hepatitis B Vaccine Booster for Health Care Workers | Annals of Family Medicine

  https://www.annfammed.org/content/23/2/162

  Confidence in hepatitis B seroprotection for US health care workers includes a complete immunization series followed by a hepatitis B surface antigen antibody (anti-HBs) titer 10 mIU/mL. […] Health care workers, particularly trainees, are at increased risk of hepatitis B infection via accidental occupational blood or body fluid exposure. In the United States, health care workers are considered fully protected after showing a hepatitis B surface antigen antibody (anti-HBs) titer 10 mIU/mL drawn 30 days after a full vaccination series. […] Both groups achieved a high level of response to a single booster dose of hepatitis B vaccine. […] Given the high response rate to a single booster, these data suggest that a single booster is reasonable for young, healthy, health care workers who never showed seropositivity. Heplisav-B was more effective than standard hepatitis B vaccine in this study population; however, further research is needed to determine if the observed effect is replicable in other populations and if the magnitude of that effect justifies the increased per-dose cost of Heplisav-B.

• #53 Heplisav-B vs Standard Hepatitis B Vaccine Booster for Health Care Workers | Annals of Family Medicine

  https://www.annfammed.org/content/23/2/162

  Confidence in hepatitis B seroprotection for US health care workers includes a complete immunization series followed by a hepatitis B surface antigen antibody (anti-HBs) titer 10 mIU/mL. […] Health care workers, particularly trainees, are at increased risk of hepatitis B infection via accidental occupational blood or body fluid exposure. In the United States, health care workers are considered fully protected after showing a hepatitis B surface antigen antibody (anti-HBs) titer 10 mIU/mL drawn 30 days after a full vaccination series. […] Both groups achieved a high level of response to a single booster dose of hepatitis B vaccine. […] Given the high response rate to a single booster, these data suggest that a single booster is reasonable for young, healthy, health care workers who never showed seropositivity. Heplisav-B was more effective than standard hepatitis B vaccine in this study population; however, further research is needed to determine if the observed effect is replicable in other populations and if the magnitude of that effect justifies the increased per-dose cost of Heplisav-B.

• #54 Azthena logo with the word Azthena

  https://www.news-medical.net/news/20250324/New-hepatitis-B-vaccine-outperforms-standard-boosters-in-health-care-workers.aspx

  Health care workers are at higher risk of hepatitis B infection due to occupational exposure to blood and body fluids. They are considered protected if they have a hepatitis B surface antigen antibody (anti-HBs) titer of 10 mIU/mL after completing a full vaccination series. […] The study findings suggest that a single booster dose is sufficient to confirm hepatitis B immunity in most young, healthy health care workers who previously completed a full vaccination series. Heplisav-B was more effective than standard hepatitis B vaccines.

• #55 Hepatitis B Vaccine – Drugs and Lactation Database (LactMed®) – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK500943/

  The Centers for Disease Control and Prevention and several health professional organizations state that vaccines given to a nursing mother do not affect the safety of breastfeeding infants and that breastfeeding is not a contraindication to the hepatitis B vaccine. Hepatitis B vaccine is recommended along with hepatitis B immune globulin to be given by injection to infants of mothers who are positive for hepatitis B surface antigen. No differences exist in infection rates between breastfed and formula-fed infants born to hepatitis B-infected women, as long as the infant receives these preventative measures at birth. […] Breastfeeding improves the infants response to hepatitis B immunization. […] Mothers with hepatitis B are encouraged to breastfeed their infants after their infants receive these preventative measures.

• #56 Hepatitis B Vaccine – Drugs and Lactation Database (LactMed®) – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK500943/

  The Centers for Disease Control and Prevention and several health professional organizations state that vaccines given to a nursing mother do not affect the safety of breastfeeding infants and that breastfeeding is not a contraindication to the hepatitis B vaccine. Hepatitis B vaccine is recommended along with hepatitis B immune globulin to be given by injection to infants of mothers who are positive for hepatitis B surface antigen. No differences exist in infection rates between breastfed and formula-fed infants born to hepatitis B-infected women, as long as the infant receives these preventative measures at birth. […] Breastfeeding improves the infants response to hepatitis B immunization. […] Mothers with hepatitis B are encouraged to breastfeed their infants after their infants receive these preventative measures.

• #57 Hepatitis B Vaccine – Drugs and Lactation Database (LactMed®) – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK500943/

  Breastfeeding also appears to reduce infant side effects associated with routine childhood immunization. Breastfed infants should be vaccinated according to the routine recommended schedules. […] Breastfeeding can enhance the response of the infant to certain vaccine antigens. […] Breastfed infants are also less likely to have fever and may be less likely to experience anorexia and reduced energy intake after routine childhood immunization than those who are not breastfed. […] Breastfed infants of hepatitis B surface antigen positive mothers have a different response in the development of immunoglobulin subtypes after vaccination with hepatitis B vaccine than do formula-fed infants. However, breastfeeding does not interfere with the infant’s antibody response to hepatitis B vaccine.

• #58 Hepatitis B Vaccine – Drugs and Lactation Database (LactMed®) – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK500943/

  The Centers for Disease Control and Prevention and several health professional organizations state that vaccines given to a nursing mother do not affect the safety of breastfeeding infants and that breastfeeding is not a contraindication to the hepatitis B vaccine. Hepatitis B vaccine is recommended along with hepatitis B immune globulin to be given by injection to infants of mothers who are positive for hepatitis B surface antigen. No differences exist in infection rates between breastfed and formula-fed infants born to hepatitis B-infected women, as long as the infant receives these preventative measures at birth. […] Breastfeeding improves the infants response to hepatitis B immunization. […] Mothers with hepatitis B are encouraged to breastfeed their infants after their infants receive these preventative measures.

• #59 Hepatitis B Vaccine – Drugs and Lactation Database (LactMed®) – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK500943/

  The Centers for Disease Control and Prevention and several health professional organizations state that vaccines given to a nursing mother do not affect the safety of breastfeeding infants and that breastfeeding is not a contraindication to the hepatitis B vaccine. Hepatitis B vaccine is recommended along with hepatitis B immune globulin to be given by injection to infants of mothers who are positive for hepatitis B surface antigen. No differences exist in infection rates between breastfed and formula-fed infants born to hepatitis B-infected women, as long as the infant receives these preventative measures at birth. […] Breastfeeding improves the infants response to hepatitis B immunization. […] Mothers with hepatitis B are encouraged to breastfeed their infants after their infants receive these preventative measures.

• #60 Nurses need to help wipe out chronic hepatitis B, a disease borne by 300 million people – Hepatitis B Foundation

  https://www.hepb.org/blog/nurses-need-help-wipe-chronic-hepatitis-b-disease-borne-300-million-people/

  First and foremost, determining the why in what is making the parent hesitant about or declining the hep B vaccine is vital when trying to help them understand the reason vaccination is strongly advised. […] Educating parents about complications that acquiring hepatitis B can have on the body can emphasize the vaccines purpose. […] Nurses need to use language that is concise and easy to understand. […] Nurses can let parents know hepatitis B is a virus that causes inflammation of the liver that damages and compromises its function, which can and often does lead to liver disease and ultimately cancer. […] Unlike a common bacterial infection that can quickly be treated with antibiotics, acquiring a hepatitis B infection can mean living with a chronic, life-long and potentially life-threatening illness.

• #61 Nurses need to help wipe out chronic hepatitis B, a disease borne by 300 million people – Hepatitis B Foundation

  https://www.hepb.org/blog/nurses-need-help-wipe-chronic-hepatitis-b-disease-borne-300-million-people/

  First and foremost, determining the why in what is making the parent hesitant about or declining the hep B vaccine is vital when trying to help them understand the reason vaccination is strongly advised. […] Educating parents about complications that acquiring hepatitis B can have on the body can emphasize the vaccines purpose. […] Nurses need to use language that is concise and easy to understand. […] Nurses can let parents know hepatitis B is a virus that causes inflammation of the liver that damages and compromises its function, which can and often does lead to liver disease and ultimately cancer. […] Unlike a common bacterial infection that can quickly be treated with antibiotics, acquiring a hepatitis B infection can mean living with a chronic, life-long and potentially life-threatening illness.

• #62 Nurses need to help wipe out chronic hepatitis B, a disease borne by 300 million people – Hepatitis B Foundation

  https://www.hepb.org/blog/nurses-need-help-wipe-chronic-hepatitis-b-disease-borne-300-million-people/

  First and foremost, determining the why in what is making the parent hesitant about or declining the hep B vaccine is vital when trying to help them understand the reason vaccination is strongly advised. […] Educating parents about complications that acquiring hepatitis B can have on the body can emphasize the vaccines purpose. […] Nurses need to use language that is concise and easy to understand. […] Nurses can let parents know hepatitis B is a virus that causes inflammation of the liver that damages and compromises its function, which can and often does lead to liver disease and ultimately cancer. […] Unlike a common bacterial infection that can quickly be treated with antibiotics, acquiring a hepatitis B infection can mean living with a chronic, life-long and potentially life-threatening illness.

• #63 Nurses need to help wipe out chronic hepatitis B, a disease borne by 300 million people – Hepatitis B Foundation

  https://www.hepb.org/blog/nurses-need-help-wipe-chronic-hepatitis-b-disease-borne-300-million-people/

  First and foremost, determining the why in what is making the parent hesitant about or declining the hep B vaccine is vital when trying to help them understand the reason vaccination is strongly advised. […] Educating parents about complications that acquiring hepatitis B can have on the body can emphasize the vaccines purpose. […] Nurses need to use language that is concise and easy to understand. […] Nurses can let parents know hepatitis B is a virus that causes inflammation of the liver that damages and compromises its function, which can and often does lead to liver disease and ultimately cancer. […] Unlike a common bacterial infection that can quickly be treated with antibiotics, acquiring a hepatitis B infection can mean living with a chronic, life-long and potentially life-threatening illness.

• #64 Nurses need to help wipe out chronic hepatitis B, a disease borne by 300 million people – Hepatitis B Foundation

  https://www.hepb.org/blog/nurses-need-help-wipe-chronic-hepatitis-b-disease-borne-300-million-people/

  And the vaccine was established to provide a solution to that problem. […] A major misconception is that individuals who have hepatitis B have engaged in risky sexual behaviors or are drug users. […] To counter this impression, we want to make it very clear that hepatitis B can affect anyone. […] If a parent is on the fence about the hep B vaccine, they might come with assumptions rather than questions. […] You can let them know: The hep B vaccine is synthetically prepared with small bits of viral protein and does not contain any blood products. […] Educating parents about what the vaccine is will help explain how it actually works. […] Parents will often raise safety concerns about the vaccine and the erroneous allegations that it can cause autism. […] The most effective way to communicate with parents who harbor this misguided belief is by emphasizing the information from trusted and reliable national public health agencies.

• #65 Nurses need to help wipe out chronic hepatitis B, a disease borne by 300 million people – Hepatitis B Foundation

  https://www.hepb.org/blog/nurses-need-help-wipe-chronic-hepatitis-b-disease-borne-300-million-people/

  Nurses could inform parents that thimerosal is no longer used in the hepatitis B vaccine (or any other childhood vaccine except flu), and a page on the Childrens Hospital of Philadelphia website explains why thimerosal in vaccines isnt harmful. […] As for the hepatitis B vaccine, as you can read on the Hepatitis B Foundations website, The most highly respected public health agencies and professional medical associations have rigorously studied the safety of the hepatitis B vaccine. […] For nurses, addressing parents hesitancy and navigating a no for the hep B vaccine is priority when striving for maximum compliance. […] Nurses equipped with knowing how to voice the facts and recommendations in a way that doesnt make parents feel argued with support a greater chance at swaying the decision to vaccinate their children. […] At the end of the day, if youve exhausted all resources and information and a parent still declines the hep B vaccine, simply document and hope for reconsideration down the road.

• #66 Nurses need to help wipe out chronic hepatitis B, a disease borne by 300 million people – Hepatitis B Foundation

  https://www.hepb.org/blog/nurses-need-help-wipe-chronic-hepatitis-b-disease-borne-300-million-people/

  Nurses could inform parents that thimerosal is no longer used in the hepatitis B vaccine (or any other childhood vaccine except flu), and a page on the Childrens Hospital of Philadelphia website explains why thimerosal in vaccines isnt harmful. […] As for the hepatitis B vaccine, as you can read on the Hepatitis B Foundations website, The most highly respected public health agencies and professional medical associations have rigorously studied the safety of the hepatitis B vaccine. […] For nurses, addressing parents hesitancy and navigating a no for the hep B vaccine is priority when striving for maximum compliance. […] Nurses equipped with knowing how to voice the facts and recommendations in a way that doesnt make parents feel argued with support a greater chance at swaying the decision to vaccinate their children. […] At the end of the day, if youve exhausted all resources and information and a parent still declines the hep B vaccine, simply document and hope for reconsideration down the road.

• #67 Nurses need to help wipe out chronic hepatitis B, a disease borne by 300 million people – Hepatitis B Foundation

  https://www.hepb.org/blog/nurses-need-help-wipe-chronic-hepatitis-b-disease-borne-300-million-people/

  And the vaccine was established to provide a solution to that problem. […] A major misconception is that individuals who have hepatitis B have engaged in risky sexual behaviors or are drug users. […] To counter this impression, we want to make it very clear that hepatitis B can affect anyone. […] If a parent is on the fence about the hep B vaccine, they might come with assumptions rather than questions. […] You can let them know: The hep B vaccine is synthetically prepared with small bits of viral protein and does not contain any blood products. […] Educating parents about what the vaccine is will help explain how it actually works. […] Parents will often raise safety concerns about the vaccine and the erroneous allegations that it can cause autism. […] The most effective way to communicate with parents who harbor this misguided belief is by emphasizing the information from trusted and reliable national public health agencies.

• #68 Hepatitis B: Nursing Diagnosis & Interventions | Nurse.com

  https://www.nurse.com/clinical-guides/hepatitis-b/?srsltid=AfmBOooL5zy1njN3SmTlFQ-a7-U9Vd8kAw9fIMPseMHPJm8Imk_AxfCw

  The best treatment for hepatitis B is prevention through the hepatitis B vaccine. […] The individual with hepatitis B and their household should be vaccinated for hepatitis B. Education should include proper preventative practices to avoid the transmission of disease to others. […] Nursing interventions will vary among individuals. Some of the most common nursing interventions include: Educate individual on ways to conserve energy. […] The individual should also be aware of the importance of follow-up treatments. […] Certain medications such as acetaminophen (Tylenol) should be avoided due to the potential for liver toxicity. The individual should be educated not to take any medication or drugs unless approved by their healthcare provider. Alcohol should also be avoided.

• #69 Hepatitis B: Nursing Diagnosis & Interventions | Nurse.com

  https://www.nurse.com/clinical-guides/hepatitis-b/?srsltid=AfmBOooL5zy1njN3SmTlFQ-a7-U9Vd8kAw9fIMPseMHPJm8Imk_AxfCw

  The best treatment for hepatitis B is prevention through the hepatitis B vaccine. […] The individual with hepatitis B and their household should be vaccinated for hepatitis B. Education should include proper preventative practices to avoid the transmission of disease to others. […] Nursing interventions will vary among individuals. Some of the most common nursing interventions include: Educate individual on ways to conserve energy. […] The individual should also be aware of the importance of follow-up treatments. […] Certain medications such as acetaminophen (Tylenol) should be avoided due to the potential for liver toxicity. The individual should be educated not to take any medication or drugs unless approved by their healthcare provider. Alcohol should also be avoided.

• #70 Hepatitis B: Nursing Diagnosis & Interventions | Nurse.com

  https://www.nurse.com/clinical-guides/hepatitis-b/?srsltid=AfmBOooL5zy1njN3SmTlFQ-a7-U9Vd8kAw9fIMPseMHPJm8Imk_AxfCw

  The best treatment for hepatitis B is prevention through the hepatitis B vaccine. […] The individual with hepatitis B and their household should be vaccinated for hepatitis B. Education should include proper preventative practices to avoid the transmission of disease to others. […] Nursing interventions will vary among individuals. Some of the most common nursing interventions include: Educate individual on ways to conserve energy. […] The individual should also be aware of the importance of follow-up treatments. […] Certain medications such as acetaminophen (Tylenol) should be avoided due to the potential for liver toxicity. The individual should be educated not to take any medication or drugs unless approved by their healthcare provider. Alcohol should also be avoided.

• #71 Hepatitis B Vaccine Recombinant Monograph for Professionals – Drugs.com

  https://www.drugs.com/monograph/hepatitis-b-vaccine-recombinant.html

  Travelers to areas with levels of endemic HBV that are intermediate (2–7%) or high (≥8%) are at risk of exposure to the disease. […] ACIP and CDC recommend PEP with HepB vaccine for victims of sexual assault (adult, adolescent, child) who are susceptible to HBV. […] AAP recommends that unvaccinated infants <12 months of age in close contact with a mother or other primary caregiver who has acute HBV infection receive combined passive immunization with HBIG and active immunization with HepB vaccine. [...] If the patient with acute HBV infection becomes chronically infected (i.e., remains HBsAg-positive after 6 months), all household contacts should be vaccinated with HepB vaccine. [...] The complete HepB vaccine series must be administered to ensure optimal protection. [...] The manufacturers recommend use of HepB vaccine in these individuals.

• #72 Hepatitis B vaccine | Nursing Times

  https://www.nursingtimes.net/medicine-management/hepatitis-b-vaccine-08-10-2004/

  – Additional doses may be required for individuals with a suppressed immune system. […] – Correct cold chain vaccine storage should be ensured. […] – The injection site batch number and expiry date should be recorded in the patient record. […] – Nurses should refer to manufacturers summary of product characteristics and to appropriate local guidelines.

• #73 Hepatitis B Vaccine – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK554400/

  After completing the 3-vaccination series, patients may receive a blood test after 1 to 4 months to determine the immune response, which is defined as an anti-hepatitis B surface antigen (anti-Hbs) antibody level exceeding 100mIU/mL. […] All persons receiving the vaccine should remain under observation for at least 15 minutes following its administration for syncope or signs of anaphylaxis. […] Nurses should always verify the patient’s vaccination status regarding hepatitis B (as well as other vaccines) and report their findings to the clinician. […] All team members can increase the vaccination rate of their patients by encouraging all staff to become trained in the assessment of vaccination histories and any pertinent staff in administering the vaccine.

• #74 Hepatitis B Vaccine – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK554400/

  After completing the 3-vaccination series, patients may receive a blood test after 1 to 4 months to determine the immune response, which is defined as an anti-hepatitis B surface antigen (anti-Hbs) antibody level exceeding 100mIU/mL. […] All persons receiving the vaccine should remain under observation for at least 15 minutes following its administration for syncope or signs of anaphylaxis. […] Nurses should always verify the patient’s vaccination status regarding hepatitis B (as well as other vaccines) and report their findings to the clinician. […] All team members can increase the vaccination rate of their patients by encouraging all staff to become trained in the assessment of vaccination histories and any pertinent staff in administering the vaccine.

• #75 Hepatitis B vaccine | Nursing Times

  https://www.nursingtimes.net/medicine-management/hepatitis-b-vaccine-08-10-2004/

  – Additional doses may be required for individuals with a suppressed immune system. […] – Correct cold chain vaccine storage should be ensured. […] – The injection site batch number and expiry date should be recorded in the patient record. […] – Nurses should refer to manufacturers summary of product characteristics and to appropriate local guidelines.

• #76 Dosing and Administration Schedule for RECOMBIVAX HB® [Hepatitis B Vaccine (Recombinant)]

  https://www.merckvaccines.com/recombivax-hb/dosage-administration/

  RECOMBIVAX HB should not be administered in the gluteal region, as injections given in the buttocks have resulted in lower seroconversion rates than expected. […] Predialysis and dialysis adult patients respond less well to hepatitis B vaccines than do healthy individuals; however, vaccination of adult patients early in the course of their renal disease produces higher seroconversion rates than vaccination after dialysis has been initiated. […] Data are not available to assess the effects of RECOMBIVAX HB on the breastfed infant or on milk productions/excretion.

• #77 Understanding the Updated Hepatitis B Vaccination Recommendations and Guidance | AAFP

  https://www.aafp.org/pubs/fpm/issues/2023/0900/hepatitis-b-vaccination-recommendations.html

  Family physicians who provide obstetrical care should continue to routinely ensure their patients who are pregnant have been vaccinated for HepB, given that the perinatal period is one of the highest risks of HepB transmission to infants. […] It is recommended that women who are unvaccinated and pregnant or breastfeeding should receive Engerix-B, Recombivax HB, or Twinrix.1 Due to limited data on the impact on lactation and pregnancy safety for Heplisav-B and PreHevbrio, these vaccines are not currently recommended for those patient populations.

• #78 Hepatitis B Vaccine: Care Instructions | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.hepatitis-b-vaccine-care-instructions.zc1827

  The hepatitis B vaccine protects against infection with the hepatitis B virus. A hepatitis B infection can damage the liver and lead to liver cancer. […] The vaccine is given to adults in three doses. You receive the shots in your upper arm. You should get the second shot at least 1 month after the first one. The third shot is most often given about 6 months after the first one. After you get all three doses, you will be protected for at least 15 years. This vaccine is safe for women who are pregnant or breastfeeding. […] Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It’s also a good idea to know your test results and keep a list of the medicines you take. […] Call your doctor now or seek immediate medical care if: You have symptoms of an allergic reaction, such as: A rash or hives (raised, red areas on the skin). Itching. Swelling. Mild belly pain or nausea. You have a high fever. […] Watch closely for changes in your health, and be sure to contact your doctor if you have any problems.

• #79 Nurses need to help wipe out chronic hepatitis B, a disease borne by 300 million people – Hepatitis B Foundation

  https://www.hepb.org/blog/nurses-need-help-wipe-chronic-hepatitis-b-disease-borne-300-million-people/

  Nurses such as you and me yes, that means all nurses (and our welcomed health care counterparts) likely come across a patient or parent who declines vaccinations for themselves or their children. […] While every nurse may provide vaccine education at some point in a patients life, those in neonatal and maternal-newborn nursing have a greater responsibility with the hepatitis B vaccine. […] However, communicating those reasons to parents of our newborn patients takes a compassionate, strong and skillful approach. […] There are various clinical settings and times when nurses can educate new parents and those with children about how the hepatitis B vaccine works and why it is necessary. […] When addressing the highly recommended CDCs vaccine schedule with parents, the rule of thumb is letting them know to expect their child will get the hep B vaccine series starting at birth.

• #80 Benefits of Hepatitis B Vaccines in Healthcare Workers

  https://www.uspharmacist.com/article/benefits-of-hepatitis-b-vaccines-in-healthcare-workers

  According to a study published in Cureus, enhancing educational initiatives and improving access to HBV vaccination are essential to ensure better protection against HBV infections for healthcare workers. The authors wrote, Hepatitis B virus is a significant occupational hazard for healthcare workers worldwide. Long-term protection against hepatitis B infection is conferred by the vaccine and the protective immune response is indicated by anti-hepatitis B surface antigen (HBsAg) titre. The authors also indicated that evaluating the HBV vaccination status of healthcare workers provides an essential understanding of the immunization protocols and the significance of protection against HBV infection within this high-risk population. […] Results revealed that protective antibody levels (10 IU/mL) were detected in 84.8% of participants, with the greatest protection among physicians (94.5%), followed by laboratory technicians (82.9%) and attendants (66.6%); however, 15.2% were reported to have insufficient immunity, principally among attendants (33.3%).

• #81 Benefits of Hepatitis B Vaccines in Healthcare Workers

  https://www.uspharmacist.com/article/benefits-of-hepatitis-b-vaccines-in-healthcare-workers

  The authors wrote, The absence of HBsAg-positive cases among all study participants is a positive finding, indicating no active HBV infection within the laboratory personnel at the time of the study. This result suggests that the existing preventive measures, including vaccination and other infection control practices, are effective in preventing HBV transmission among these workers. […] Based on their findings, the authors concluded that this study stressed the importance of effective preventive strategies against HBV among laboratory healthcare workers, as shown by the absence of active infections. Finally, the authors noted that the findings emphasized the necessity of implementing concentrated and practical initiatives to expand awareness about HBV vaccinations and the significance of vaccination, particularly among attendants, to ensure comprehensive protection against HBV infections for all levels of laboratory staff members.

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