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• #1 Patient education: Chronic cough in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-cough-in-adults-beyond-the-basics

  Chronic cough treatment aims to eliminate the underlying cause. […] Treatment of chronic cough aims to eliminate the underlying cause. Most of the time, each type of treatment is tried separately, one after another, instead of all at the same time. […] Here are some examples of treatment choices for different causes of cough. […] A cough related to postnasal drip may improve with the use of a decongestant, nasal or oral antihistamine, nasal glucocorticoid, or a nasal spray that contains ipratropium. […] If your cough is due to asthma, you will be given the standard treatment for asthma, which includes an inhaled glucocorticoid such as fluticasone (Flovent), budesonide (Pulmicort), or beclomethasone (QVAR). […] Cough due to acid reflux may respond to the following lifestyle changes: Avoid substances that increase reflux, such as high-fat foods, chocolate, colas, red wine, acidic juices, and excessive alcohol.

• #2 Patient education: Chronic cough in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-cough-in-adults-beyond-the-basics/print

  Chronic cough treatment aims to eliminate the underlying cause. […] Most of the time, each type of treatment is tried separately, one after another, instead of all at the same time. […] Here are some examples of treatment choices for different causes of cough. […] A cough related to postnasal drip may improve with the use of a decongestant, nasal or oral antihistamine, nasal glucocorticoid, or a nasal spray that contains ipratropium. […] If your cough is due to asthma, you will be given the standard treatment for asthma, which includes an inhaled glucocorticoid such as fluticasone (Flovent), budesonide (Pulmicort), or beclomethasone (QVAR). […] Cough due to acid reflux may respond to the following lifestyle changes: Avoid substances that increase reflux, such as high-fat foods, chocolate, colas, red wine, acidic juices, and excessive alcohol. […] Eosinophilic bronchitis is treated with inhaled glucocorticoids. […] If, after a thorough evaluation, the cause of your cough cannot be determined and the cough persists, a medication that suppresses your cough may be recommended.

• #3 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Finding out what’s causing a chronic cough is very important to effective treatment. In many cases, more than one underlying condition may be causing your chronic cough. […] If you smoke, your healthcare professional likely will talk with you about your readiness to quit and give you advice on how to achieve this goal. If you’re taking an ACE inhibitor medicine, your health professional may switch you to another medicine that doesn’t have cough as a side effect. […] Medicines used to treat chronic cough may include: […] Antihistamines, corticosteroids and decongestants. These medicines are standard treatment for allergies and postnasal drip. […] Inhaled asthma medicines. The most effective treatments for asthma-related cough are corticosteroids and bronchodilators. They reduce inflammation and open up your airways.

• #4 Chronic Cough | Condition | UT Southwestern Medical Center

  https://utswmed.org/conditions-treatments/chronic-cough/

  UT Southwestern Medical Center provides expert care for people who have a chronic cough and other conditions affecting the airways, larynx (voice box), throat, and lungs. Using the latest technology, we work to evaluate, diagnose, and treat the underlying causes of chronic cough. […] Our multidisciplinary approach often combines the expertise of fellowship-trained laryngologists, pulmonologists, speech-language pathologists, allergists, and other care professionals focused on voice, throat, and lung conditions. Our physicians, therapists, and researchers are widely recognized as experts in the accurate diagnosis and effective treatment of chronic cough. […] Treatment for chronic cough involves remedying the underlying cause, and options include: […] Cough suppressant medications to control the cough […] Cough suppression techniques, taught by our speech-language pathologists, to help reduce the severity and frequency of the cough.

• #5 Get Chronic Cough Treatment | Cleveland Clinic

  https://my.clevelandclinic.org/services/chronic-cough-treatment

  If allergies are contributing to your constant cough, we may prescribe antihistamines, which can relieve allergy symptoms, like coughing and antacids to neutralize the stomach acid irritating your throat. […] Your chronic cough could also be a side effect of drugs used to treat high blood pressure. You and your provider can talk about trying other blood pressure medications if youre having this side effect. […] Your provider may recommend behavioral cough suppression therapy (BCST). Our specialized therapists teach you how to control your urge to cough with behavioral techniques. Your treatment plan may combine BCST and medication to suppress your chronic cough. […] Our chronic cough clinic offers the newest tests and innovative treatments if traditional therapies arent making your symptoms go away. We offer: Lab tests to see if there are bacteria in your blood or phlegm. Lung function tests, like spirometry, to check how well your lungs are working. Imaging tests, like chest X-rays, CT scans, MRIs, ultrasound and nuclear testing to get a closer, more detailed look inside your body. […] You dont have to live with it. You can get relief. Cleveland Clinic healthcare providers are here to help you find relief by building a personalized treatment plan that will silence your chronic cough.

• #6 Treatment of Unexplained Chronic Cough

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5831652/

  Unexplained chronic cough (UCC) causes significant impairments in quality of life. Effective assessment and treatment approaches are needed for UCC. […] The evidence supporting the diagnosis and management of UCC is limited. UCC requires further study to establish agreed terminology and the optimal methods of investigation using established criteria for intervention fidelity. Speech pathology-based cough suppression is suggested as a treatment option for UCC. […] In adult patients with unexplained chronic cough, we suggest a therapeutic trial of multimodality speech pathology therapy. […] In adult patients with unexplained chronic cough, we suggest a therapeutic trial of gabapentin as long as the potential side effects and the risk-benefit profile are discussed with patients before use of the medication, and there is a reassessment of the risk-benefit profile at 6 months before continuing the drug.

• #7 Patient education: Chronic cough in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-cough-in-adults-beyond-the-basics

  Chronic cough treatment aims to eliminate the underlying cause. […] Treatment of chronic cough aims to eliminate the underlying cause. Most of the time, each type of treatment is tried separately, one after another, instead of all at the same time. […] Here are some examples of treatment choices for different causes of cough. […] A cough related to postnasal drip may improve with the use of a decongestant, nasal or oral antihistamine, nasal glucocorticoid, or a nasal spray that contains ipratropium. […] If your cough is due to asthma, you will be given the standard treatment for asthma, which includes an inhaled glucocorticoid such as fluticasone (Flovent), budesonide (Pulmicort), or beclomethasone (QVAR). […] Cough due to acid reflux may respond to the following lifestyle changes: Avoid substances that increase reflux, such as high-fat foods, chocolate, colas, red wine, acidic juices, and excessive alcohol.

• #8 Patient education: Chronic cough in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-cough-in-adults-beyond-the-basics/print

  Chronic cough treatment aims to eliminate the underlying cause. […] Most of the time, each type of treatment is tried separately, one after another, instead of all at the same time. […] Here are some examples of treatment choices for different causes of cough. […] A cough related to postnasal drip may improve with the use of a decongestant, nasal or oral antihistamine, nasal glucocorticoid, or a nasal spray that contains ipratropium. […] If your cough is due to asthma, you will be given the standard treatment for asthma, which includes an inhaled glucocorticoid such as fluticasone (Flovent), budesonide (Pulmicort), or beclomethasone (QVAR). […] Cough due to acid reflux may respond to the following lifestyle changes: Avoid substances that increase reflux, such as high-fat foods, chocolate, colas, red wine, acidic juices, and excessive alcohol. […] Eosinophilic bronchitis is treated with inhaled glucocorticoids. […] If, after a thorough evaluation, the cause of your cough cannot be determined and the cough persists, a medication that suppresses your cough may be recommended.

• #9 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Finding out what’s causing a chronic cough is very important to effective treatment. In many cases, more than one underlying condition may be causing your chronic cough. […] If you smoke, your healthcare professional likely will talk with you about your readiness to quit and give you advice on how to achieve this goal. If you’re taking an ACE inhibitor medicine, your health professional may switch you to another medicine that doesn’t have cough as a side effect. […] Medicines used to treat chronic cough may include: […] Antihistamines, corticosteroids and decongestants. These medicines are standard treatment for allergies and postnasal drip. […] Inhaled asthma medicines. The most effective treatments for asthma-related cough are corticosteroids and bronchodilators. They reduce inflammation and open up your airways.

• #10 Cough Relief: How to Get Rid of a Bad Cough

  https://www.webmd.com/cold-and-flu/cough-get-rid-home-hacks

  You can manage allergy cough with: Antihistamines. These medicines block histamine, a substance released by your immune system, which causes your allergy symptoms. […] A dry cough is one that doesn’t produce mucus or phlegm. It may occur when you have conditions such as the cold or flu or more serious conditions like asthma, pneumonia, heart failure, tuberculosis, and chronic obstructive pulmonary disease (COPD). […] Taking over-the-counter cough medicines like cough expectorants may not work. But you can manage it with: Hydration. Staying hydrated by drinking water, warm teas, or honey and lemon water may help soothe your airways and reduce your cough. […] As you treat the underlying condition causing the cough, you can also find relief with over-the-counter medicines such as cough suppressants, cough drops, and lozenges, as well as by staying hydrated.

• #11 Chronic Cough: Practice Essentials, Mechanism of Cough, Causes of Chronic Cough

  https://emedicine.medscape.com/article/1048560-overview

  Other management strategies include the following: UACS – Management includes avoidance of environmental irritants and offending antigens, treatment of sinusitis with antibiotics, and weaning of patients off nasal decongestants for rhinitis medicamentosa; for patients in whom the cause is not apparent, empiric therapy should be instituted with a combination of an antihistamine and decongestant. […] The initial treatment of asthma consists of beta-2 agonists and inhaled corticosteroids (ICS), and response is usually seen within 1 week, with complete resolution taking up to 8 weeks; some patients may require a trial of oral corticosteroids before a response is seen; however, because leukotriene inhibitors have been shown to be effective in patients with asthma-induced cough, they should be tried prior to oral corticosteroid therapy.

• #12 Chronic Cough: Evaluation and Management | AAFP

  https://www.aafp.org/pubs/afp/issues/2017/1101/p575.html

  For severe or refractory cough, a five- to 10-day course of prednisone, 40 to 60 mg, or equivalent oral corticosteroid can be considered if asthma is strongly suspected. […] Nonasthmatic eosinophilic bronchitis is characterized by chronic cough in patients with no symptoms or objective evidence of variable airflow obstruction, normal airway responsiveness on a methacholine inhalation test, and sputum eosinophilia. […] It does not respond to inhaled bronchodilators, but should respond to inhaled corticosteroids. […] Consensus guidelines recommend empiric therapy for at least eight weeks in conjunction with lifestyle changes such as dietary changes and weight loss. […] Patients with unexplained chronic cough after evaluation and treatment of common causes should be referred to a pulmonologist or otolaryngologist.

• #13 Patient education: Chronic cough in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-cough-in-adults-beyond-the-basics/print

  Chronic cough treatment aims to eliminate the underlying cause. […] Most of the time, each type of treatment is tried separately, one after another, instead of all at the same time. […] Here are some examples of treatment choices for different causes of cough. […] A cough related to postnasal drip may improve with the use of a decongestant, nasal or oral antihistamine, nasal glucocorticoid, or a nasal spray that contains ipratropium. […] If your cough is due to asthma, you will be given the standard treatment for asthma, which includes an inhaled glucocorticoid such as fluticasone (Flovent), budesonide (Pulmicort), or beclomethasone (QVAR). […] Cough due to acid reflux may respond to the following lifestyle changes: Avoid substances that increase reflux, such as high-fat foods, chocolate, colas, red wine, acidic juices, and excessive alcohol. […] Eosinophilic bronchitis is treated with inhaled glucocorticoids. […] If, after a thorough evaluation, the cause of your cough cannot be determined and the cough persists, a medication that suppresses your cough may be recommended.

• #14 Chronic Cough: Practice Essentials, Mechanism of Cough, Causes of Chronic Cough

  https://emedicine.medscape.com/article/1048560-overview

  Other management strategies include the following: UACS – Management includes avoidance of environmental irritants and offending antigens, treatment of sinusitis with antibiotics, and weaning of patients off nasal decongestants for rhinitis medicamentosa; for patients in whom the cause is not apparent, empiric therapy should be instituted with a combination of an antihistamine and decongestant. […] The initial treatment of asthma consists of beta-2 agonists and inhaled corticosteroids (ICS), and response is usually seen within 1 week, with complete resolution taking up to 8 weeks; some patients may require a trial of oral corticosteroids before a response is seen; however, because leukotriene inhibitors have been shown to be effective in patients with asthma-induced cough, they should be tried prior to oral corticosteroid therapy.

• #15 Chronic Cough: Practice Essentials, Mechanism of Cough, Causes of Chronic Cough

  https://emedicine.medscape.com/article/1048560-overview

  Other management strategies include the following: UACS – Management includes avoidance of environmental irritants and offending antigens, treatment of sinusitis with antibiotics, and weaning of patients off nasal decongestants for rhinitis medicamentosa; for patients in whom the cause is not apparent, empiric therapy should be instituted with a combination of an antihistamine and decongestant. […] The initial treatment of asthma consists of beta-2 agonists and inhaled corticosteroids (ICS), and response is usually seen within 1 week, with complete resolution taking up to 8 weeks; some patients may require a trial of oral corticosteroids before a response is seen; however, because leukotriene inhibitors have been shown to be effective in patients with asthma-induced cough, they should be tried prior to oral corticosteroid therapy.

• #16 Patient education: Chronic cough in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-cough-in-adults-beyond-the-basics/print

  Chronic cough treatment aims to eliminate the underlying cause. […] Most of the time, each type of treatment is tried separately, one after another, instead of all at the same time. […] Here are some examples of treatment choices for different causes of cough. […] A cough related to postnasal drip may improve with the use of a decongestant, nasal or oral antihistamine, nasal glucocorticoid, or a nasal spray that contains ipratropium. […] If your cough is due to asthma, you will be given the standard treatment for asthma, which includes an inhaled glucocorticoid such as fluticasone (Flovent), budesonide (Pulmicort), or beclomethasone (QVAR). […] Cough due to acid reflux may respond to the following lifestyle changes: Avoid substances that increase reflux, such as high-fat foods, chocolate, colas, red wine, acidic juices, and excessive alcohol. […] Eosinophilic bronchitis is treated with inhaled glucocorticoids. […] If, after a thorough evaluation, the cause of your cough cannot be determined and the cough persists, a medication that suppresses your cough may be recommended.

• #17 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Finding out what’s causing a chronic cough is very important to effective treatment. In many cases, more than one underlying condition may be causing your chronic cough. […] If you smoke, your healthcare professional likely will talk with you about your readiness to quit and give you advice on how to achieve this goal. If you’re taking an ACE inhibitor medicine, your health professional may switch you to another medicine that doesn’t have cough as a side effect. […] Medicines used to treat chronic cough may include: […] Antihistamines, corticosteroids and decongestants. These medicines are standard treatment for allergies and postnasal drip. […] Inhaled asthma medicines. The most effective treatments for asthma-related cough are corticosteroids and bronchodilators. They reduce inflammation and open up your airways.

• #18 Patient education: Chronic cough in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-cough-in-adults-beyond-the-basics

  Chronic cough treatment aims to eliminate the underlying cause. […] Treatment of chronic cough aims to eliminate the underlying cause. Most of the time, each type of treatment is tried separately, one after another, instead of all at the same time. […] Here are some examples of treatment choices for different causes of cough. […] A cough related to postnasal drip may improve with the use of a decongestant, nasal or oral antihistamine, nasal glucocorticoid, or a nasal spray that contains ipratropium. […] If your cough is due to asthma, you will be given the standard treatment for asthma, which includes an inhaled glucocorticoid such as fluticasone (Flovent), budesonide (Pulmicort), or beclomethasone (QVAR). […] Cough due to acid reflux may respond to the following lifestyle changes: Avoid substances that increase reflux, such as high-fat foods, chocolate, colas, red wine, acidic juices, and excessive alcohol.

• #19 Chronic Cough: Causes, Treatment, and More

  https://www.healthline.com/health/chronic-cough

  Drugs used to treat asthma can include inhaled steroids and bronchodilators, which require a prescription. These medicines bring down swelling in the airways and widen narrowed air passages to help you breathe more easily. […] Antibiotics can help treat pneumonia or other bacterial infections, such as whooping cough. […] Decongestants can dry up secretions. Antihistamines and steroid nasal sprays can block the allergic response that causes mucus production and help bring down swelling in your nasal passages. […] Speech therapy may be effective in lowering the severity of a chronic cough. Your doctor can provide you with a referral to a speech therapist. […] Cough medicines that contain dextromethorphan (Mucinex, Robitussin) may help relax the cough reflex. […] If OTC options don’t help, your doctor may prescribe a medication, such as benzonatate (Tessalon). This numbs the cough reflex. […] Researchers are continuing to study new treatments that may relieve chronic cough in people who haven’t responded to other therapies. This is likely to lead to more effective treatments in the future.

• #20 Chronic Cough: Evaluation and Management | AAFP

  https://www.aafp.org/pubs/afp/issues/2017/1101/p575.html

  In patients with refractory chronic cough, referral to a pulmonologist or otolaryngologist should be considered, as well as a trial of gabapentin (Neurontin), pregabalin (Lyrica), or speech therapy. […] The diagnostic approach should focus on detection and treatment of the four most common causes of chronic cough in adults: upper airway cough syndrome (UACS), asthma, nonasthmatic eosinophilic bronchitis, and gastroesophageal reflux disease (GERD)/laryngopharyngeal reflux disease. […] If a specific cause is identified, therapy should be started; otherwise, initial treatment includes a decongestant combined with a first-generation antihistamine. […] Treatment usually includes an inhaled bronchodilator and high-dose inhaled corticosteroid. A leukotriene receptor antagonist (e.g., montelukast [Singulair]) can also be useful.

• #21 Chronic Cough: Evaluation and Management | AAFP

  https://www.aafp.org/pubs/afp/issues/2017/1101/p575.html

  For severe or refractory cough, a five- to 10-day course of prednisone, 40 to 60 mg, or equivalent oral corticosteroid can be considered if asthma is strongly suspected. […] Nonasthmatic eosinophilic bronchitis is characterized by chronic cough in patients with no symptoms or objective evidence of variable airflow obstruction, normal airway responsiveness on a methacholine inhalation test, and sputum eosinophilia. […] It does not respond to inhaled bronchodilators, but should respond to inhaled corticosteroids. […] Consensus guidelines recommend empiric therapy for at least eight weeks in conjunction with lifestyle changes such as dietary changes and weight loss. […] Patients with unexplained chronic cough after evaluation and treatment of common causes should be referred to a pulmonologist or otolaryngologist.

• #22 Chronic Cough: Evaluation and Management | AAFP

  https://www.aafp.org/pubs/afp/issues/2017/1101/p575.html

  For severe or refractory cough, a five- to 10-day course of prednisone, 40 to 60 mg, or equivalent oral corticosteroid can be considered if asthma is strongly suspected. […] Nonasthmatic eosinophilic bronchitis is characterized by chronic cough in patients with no symptoms or objective evidence of variable airflow obstruction, normal airway responsiveness on a methacholine inhalation test, and sputum eosinophilia. […] It does not respond to inhaled bronchodilators, but should respond to inhaled corticosteroids. […] Consensus guidelines recommend empiric therapy for at least eight weeks in conjunction with lifestyle changes such as dietary changes and weight loss. […] Patients with unexplained chronic cough after evaluation and treatment of common causes should be referred to a pulmonologist or otolaryngologist.

• #23 Patient education: Chronic cough in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-cough-in-adults-beyond-the-basics

  Eosinophilic bronchitis is treated with inhaled glucocorticoids. […] If, after a thorough evaluation, the cause of your cough cannot be determined and the cough persists, a medication that suppresses your cough may be recommended. Possible options include: Nonprescription cough medicines that contain dextromethorphan (Delsym) may help suppress the cough reflex. […] Gabapentin or pregabalin, which are drugs more commonly used to ameliorate chronic pain by blocking nerve impulses, may be helpful in some patients with chronic cough.

• #24 Patient education: Chronic cough in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-cough-in-adults-beyond-the-basics/print

  Chronic cough treatment aims to eliminate the underlying cause. […] Most of the time, each type of treatment is tried separately, one after another, instead of all at the same time. […] Here are some examples of treatment choices for different causes of cough. […] A cough related to postnasal drip may improve with the use of a decongestant, nasal or oral antihistamine, nasal glucocorticoid, or a nasal spray that contains ipratropium. […] If your cough is due to asthma, you will be given the standard treatment for asthma, which includes an inhaled glucocorticoid such as fluticasone (Flovent), budesonide (Pulmicort), or beclomethasone (QVAR). […] Cough due to acid reflux may respond to the following lifestyle changes: Avoid substances that increase reflux, such as high-fat foods, chocolate, colas, red wine, acidic juices, and excessive alcohol. […] Eosinophilic bronchitis is treated with inhaled glucocorticoids. […] If, after a thorough evaluation, the cause of your cough cannot be determined and the cough persists, a medication that suppresses your cough may be recommended.

• #25 Patient education: Chronic cough in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-cough-in-adults-beyond-the-basics

  Chronic cough treatment aims to eliminate the underlying cause. […] Treatment of chronic cough aims to eliminate the underlying cause. Most of the time, each type of treatment is tried separately, one after another, instead of all at the same time. […] Here are some examples of treatment choices for different causes of cough. […] A cough related to postnasal drip may improve with the use of a decongestant, nasal or oral antihistamine, nasal glucocorticoid, or a nasal spray that contains ipratropium. […] If your cough is due to asthma, you will be given the standard treatment for asthma, which includes an inhaled glucocorticoid such as fluticasone (Flovent), budesonide (Pulmicort), or beclomethasone (QVAR). […] Cough due to acid reflux may respond to the following lifestyle changes: Avoid substances that increase reflux, such as high-fat foods, chocolate, colas, red wine, acidic juices, and excessive alcohol.

• #26 Get Chronic Cough Treatment | Cleveland Clinic

  https://my.clevelandclinic.org/services/chronic-cough-treatment

  If allergies are contributing to your constant cough, we may prescribe antihistamines, which can relieve allergy symptoms, like coughing and antacids to neutralize the stomach acid irritating your throat. […] Your chronic cough could also be a side effect of drugs used to treat high blood pressure. You and your provider can talk about trying other blood pressure medications if youre having this side effect. […] Your provider may recommend behavioral cough suppression therapy (BCST). Our specialized therapists teach you how to control your urge to cough with behavioral techniques. Your treatment plan may combine BCST and medication to suppress your chronic cough. […] Our chronic cough clinic offers the newest tests and innovative treatments if traditional therapies arent making your symptoms go away. We offer: Lab tests to see if there are bacteria in your blood or phlegm. Lung function tests, like spirometry, to check how well your lungs are working. Imaging tests, like chest X-rays, CT scans, MRIs, ultrasound and nuclear testing to get a closer, more detailed look inside your body. […] You dont have to live with it. You can get relief. Cleveland Clinic healthcare providers are here to help you find relief by building a personalized treatment plan that will silence your chronic cough.

• #27 Chronic Cough: Causes, Treatment, and More

  https://www.healthline.com/health/chronic-cough

  Chronic cough is when you have a cough that lasts for eight weeks or longer. The treatment depends on the cause. A home remedy may be sufficient, or you may need to see a doctor for medical treatment. […] Even chronic coughs often have a treatable cause. They can result from conditions like postnasal drip or allergies. Only rarely are they a symptom of cancer or other potentially life threatening lung conditions. […] It may help to know that chronic cough often has a treatable cause. The first step is talking with your doctor. They can help you get you started with a treatment plan to relieve or manage your cough. […] Treatment will depend on the cause of your cough. Some of the more common causes include: […] Your doctor may recommend changes to your diet and lifestyle. They may also recommend medications to neutralize, reduce, or block acid production. Reflux medicines include: antacids, H2 receptor blockers, proton pump inhibitors.

• #28 Chronic Cough: Causes, Treatment, and More

  https://www.healthline.com/health/chronic-cough

  Chronic cough is when you have a cough that lasts for eight weeks or longer. The treatment depends on the cause. A home remedy may be sufficient, or you may need to see a doctor for medical treatment. […] Even chronic coughs often have a treatable cause. They can result from conditions like postnasal drip or allergies. Only rarely are they a symptom of cancer or other potentially life threatening lung conditions. […] It may help to know that chronic cough often has a treatable cause. The first step is talking with your doctor. They can help you get you started with a treatment plan to relieve or manage your cough. […] Treatment will depend on the cause of your cough. Some of the more common causes include: […] Your doctor may recommend changes to your diet and lifestyle. They may also recommend medications to neutralize, reduce, or block acid production. Reflux medicines include: antacids, H2 receptor blockers, proton pump inhibitors.

• #29 Chronic Cough Treatments | Northwestern Medicine

  https://www.nm.org/conditions-and-care-areas/pulmonary/chronic-cough/treatments

  Treatment for chronic cough will depend on the underlying medical condition thats causing it. Once a diagnosis is made, your physician may recommend one or more of these treatments: […] Quitting smoking […] Antihistamines or decongestants for postnasal drip or allergies […] Acid blocking medication for GERD […] Inhalant medications for asthma […] Alternate medications for hypertension or heart failure to replace ace inhibitors […] Surgery for tumors or blockages […] Lifestyle changes, including: Drinking more water […] Humidifying your workplace and bedroom […] Raising the head of your bed or using more pillows when sleeping. […] Medications […] Surgery.

• #30 Chronic Cough: Practice Essentials, Mechanism of Cough, Causes of Chronic Cough

  https://emedicine.medscape.com/article/1048560-overview

  Empiric therapy with acid suppression and lifestyle and dietary modification has been advocated as initial management; lifestyle modifications include limiting fat intake; avoiding caffeine, chocolate, mints, citrus products, alcohol, and smoking; and limiting vigorous exercise that increases intra-abdominal pressure. […] Only when management of the most common causes has failed to yield a resolution of cough should a more extensive workup begin. […] Similarities have been demonstrated between neuropathic pain and chronic cough, and centrally acting neuromodulators such as tricyclic antidepressants (amitriptyline, nortriptyline), gabapentin, and pregabalin have shown benefit in improving cough (albeit with risk of side effects). […] French guidelines on chronic cough published in 2023 include the following for first-line management: Questioning patients with chronic cough about physical, social, and psychological complications is recommended.

• #31 Chronic Cough: Evaluation and Management | AAFP

  https://www.aafp.org/pubs/afp/issues/2017/1101/p575.html

  For severe or refractory cough, a five- to 10-day course of prednisone, 40 to 60 mg, or equivalent oral corticosteroid can be considered if asthma is strongly suspected. […] Nonasthmatic eosinophilic bronchitis is characterized by chronic cough in patients with no symptoms or objective evidence of variable airflow obstruction, normal airway responsiveness on a methacholine inhalation test, and sputum eosinophilia. […] It does not respond to inhaled bronchodilators, but should respond to inhaled corticosteroids. […] Consensus guidelines recommend empiric therapy for at least eight weeks in conjunction with lifestyle changes such as dietary changes and weight loss. […] Patients with unexplained chronic cough after evaluation and treatment of common causes should be referred to a pulmonologist or otolaryngologist.

• #32 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Antibiotics. If a bacterial, fungal or mycobacterial infection is causing your chronic cough, your healthcare professional may prescribe antibiotic medicines for the infection. […] Acid blockers. When lifestyle changes don’t take care of acid reflux, you may be treated with medicines that block acid production. Some people need surgery to resolve the problem. […] Your healthcare professional works to find the cause of your cough and the best treatment for you. During that time, your healthcare professional also may prescribe a medicine to reduce coughing, called a cough suppressant. Cough suppressants are not recommended for children. […] Cough and cold medicines available without a prescription treat the symptoms of coughs and colds not the underlying disease. Research suggests that these medicines don’t work any better than no medicine at all. These medicines are not recommended for children because of potentially serious side effects, including fatal overdoses in children younger than 2 years old. […] Don’t use over-the-counter cough and cold medicines, except for fever reducers and pain relievers, to treat coughs and colds in children younger than 6 years old. Also, avoid use of these medicines for children younger than 12 years old. Check with your healthcare professional for guidance.

• #33 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Antibiotics. If a bacterial, fungal or mycobacterial infection is causing your chronic cough, your healthcare professional may prescribe antibiotic medicines for the infection. […] Acid blockers. When lifestyle changes don’t take care of acid reflux, you may be treated with medicines that block acid production. Some people need surgery to resolve the problem. […] Your healthcare professional works to find the cause of your cough and the best treatment for you. During that time, your healthcare professional also may prescribe a medicine to reduce coughing, called a cough suppressant. Cough suppressants are not recommended for children. […] Cough and cold medicines available without a prescription treat the symptoms of coughs and colds not the underlying disease. Research suggests that these medicines don’t work any better than no medicine at all. These medicines are not recommended for children because of potentially serious side effects, including fatal overdoses in children younger than 2 years old. […] Don’t use over-the-counter cough and cold medicines, except for fever reducers and pain relievers, to treat coughs and colds in children younger than 6 years old. Also, avoid use of these medicines for children younger than 12 years old. Check with your healthcare professional for guidance.

• #34 Chronic Cough: Causes and How to Treat It | MedPark Hospital

  https://www.medparkhospital.com/en-US/disease-and-treatment/chronic-cough

  For patients on ACE inhibitors (ACEI) that may cause chronic cough, your doctor may recommend switching to alternative medications. […] For those with asthma-induced cough, medications like corticosteroids and bronchodilators may help reduce inflammation and open airways. […] If the cough is caused by bacterial infections, fungal infections, or tuberculosis, antibiotics may be prescribed. […] For a cough caused by acid reflux, medications to suppress stomach acid production may be prescribed. In some cases, surgery may be necessary. […] If the chronic cough is related to a specific respiratory condition, it is important to consult a pulmonologist or respiratory specialist for targeted treatment. […] In some cases, doctors may prescribe cough suppressants to provide temporary relief while diagnosing and beginning treatment.

• #35 Chronic Cough: Symptoms, Causes, 5 Types & 5 Prevention Tips

  https://www.medicinenet.com/chronic_cough/article.htm

  Chronic cough is a cough that persists over time. Chronic cough is not a disease in itself, but rather a symptom of an underlying condition. […] Treatment for chronic cough is to identify the cause and treat it. […] The treatment of chronic cough is directed at the cause. Symptoms may be relieved with over-the-counter (OTC) cough medicines containing guaifenesin and/or dextromethorphan (these can be found as cough syrups in tablet form). […] The following are treatments for chronic cough caused by medications, conditions, or diseases. […] In severe cases of chronic cough, a healthcare professional may prescribe codeine or other similar narcotic medications, which are effective as cough suppressants. […] Infections: Bacterial pneumonia and bronchitis are typically treated with antibiotics such as cephalosporins, azithromycin (Zithromax), and other antibiotics.

• #36 Medications for Chronic Cough | NYU Langone Health

  https://nyulangone.org/conditions/chronic-cough-in-children/treatments/medications-for-chronic-cough

  At Hassenfeld Childrens Hospital at NYU Langone, treatment of children with a chronic cough depends on the underlying cause. After our doctors have identified the source of your childs symptoms, they can select the most effective medical therapy. Most children with a chronic cough feel better within a few weeks of starting treatment, especially if the cause is a bacterial infection. […] If your child has a bacterial infection, our doctors may prescribe broad-spectrum antibiotics for two weeks or longer. These medications are effective against many types of bacteria, eliminating them from the airways. […] For children with cough-variant asthma, a breathing disorder in which coughing is the only symptom, our doctors may prescribe anti-inflammatory medicines to reduce inflammation in the airways. Your childs symptoms may gradually improve within six to eight weeks after beginning asthma treatment.

• #37 Treatment of Whooping Cough | Pertussis (Whooping Cough) | CDC

  https://www.cdc.gov/pertussis/treatment/index.html

  Early antibiotic treatment for pertussis (whooping cough) may make the infection less serious. […] Healthcare providers generally treat whooping cough with antibiotics. There are several antibiotics available for treatment. […] It’s very important to treat whooping cough early, before coughing fits begin. […] Treating whooping cough early can make the illness less serious and help prevent spreading the bacteria that cause it to others. […] Whooping cough can sometimes be very serious and can cause complications, especially for babies. People with serious illness or complications need care in the hospital. […] Hospital treatment of whooping cough usually focuses on keeping breathing passages clear, monitoring breathing and giving oxygen, if needed, and preventing or treating dehydration, via fluids through the vein.

• #38 Treatment of Whooping Cough | Pertussis (Whooping Cough) | CDC

  https://www.cdc.gov/pertussis/treatment/index.html

  Early antibiotic treatment for pertussis (whooping cough) may make the infection less serious. […] Healthcare providers generally treat whooping cough with antibiotics. There are several antibiotics available for treatment. […] It’s very important to treat whooping cough early, before coughing fits begin. […] Treating whooping cough early can make the illness less serious and help prevent spreading the bacteria that cause it to others. […] Whooping cough can sometimes be very serious and can cause complications, especially for babies. People with serious illness or complications need care in the hospital. […] Hospital treatment of whooping cough usually focuses on keeping breathing passages clear, monitoring breathing and giving oxygen, if needed, and preventing or treating dehydration, via fluids through the vein.

• #39 Chronic cough – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/symptoms-causes/syc-20351575

  A chronic cough is a cough that lasts eight weeks or longer in adults, or four weeks in children. […] Fortunately, chronic cough usually goes away once the underlying issue is treated. […] See your healthcare professional if you have a cough that lasts for weeks, especially one that brings up sputum or blood, disturbs your sleep, or affects school or work. […] Most cases of chronic cough are due to these causes, which can occur alone or together: […] Chronic obstructive pulmonary disease (COPD). Also called COPD, this is a lifelong inflammatory lung disease that limits airflow from the lungs. […] Blood pressure drugs. Angiotensin-converting enzyme inhibitors, also called ACE inhibitors, which are commonly prescribed for high blood pressure and heart failure, are known to cause chronic cough in some people. […] Having a cough that doesn’t stop can be very tiring. Coughing can cause various concerns, including:

• #40 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Finding out what’s causing a chronic cough is very important to effective treatment. In many cases, more than one underlying condition may be causing your chronic cough. […] If you smoke, your healthcare professional likely will talk with you about your readiness to quit and give you advice on how to achieve this goal. If you’re taking an ACE inhibitor medicine, your health professional may switch you to another medicine that doesn’t have cough as a side effect. […] Medicines used to treat chronic cough may include: […] Antihistamines, corticosteroids and decongestants. These medicines are standard treatment for allergies and postnasal drip. […] Inhaled asthma medicines. The most effective treatments for asthma-related cough are corticosteroids and bronchodilators. They reduce inflammation and open up your airways.

• #41 Chronic Cough: Practice Essentials, Mechanism of Cough, Causes of Chronic Cough

  https://emedicine.medscape.com/article/1048560-overview

  The management of chronic cough presents a challenge for the clinician. Typically defined as a cough that persists for longer than 8 weeks, this is the most common presenting symptom in adults who seek medical treatment in an ambulatory setting. Chronic cough is estimated to occur in up to 40% of the population. […] A multidisciplinary approach is often needed, with the primary care provider coordinating care with appropriate referrals to the otolaryngologist, pulmonologist, or both, as appropriate. […] Management should begin with cessation of smoking or angiotensin-converting enzyme (ACE) inhibitor use in those patients whose history indicates such action. Most patients have a resolution of their cough within 4 weeks of smoking cessation. Cough related to ACE inhibitor use usually subsides within 2 weeks, but the median time has been reported to be 26 days.

• #42 Chronic Cough: Symptoms, Causes, 5 Types & 5 Prevention Tips

  https://www.medicinenet.com/chronic_cough/article.htm

  Patients with chronic cough who are taking blood pressure medicines called ACE inhibitors (angiotensin-converting enzyme), for example, enalapril (Vasotec), captopril (Capoten), lisinopril (Zestril, Prinivil), etc. should talk to their doctor about switching medications. […] Chronic cough in adults can sometimes be treated with home remedies. […] Consult your doctor for the home remedies that might be best for you, and talk to your doctor before taking any herbal supplements or natural remedies for chronic cough as some may interact with medications you take. […] Home remedies to ease symptoms of chronic cough include: staying hydrated, gargling with warm saltwater, cough drops, honey, and ginger. […] Chronic cough may be prevented by not smoking and managing medical problems such as asthma, postnasal drip, GERD, and getting vaccinated against whooping cough.

• #43 Get Chronic Cough Treatment | Cleveland Clinic

  https://my.clevelandclinic.org/services/chronic-cough-treatment

  If allergies are contributing to your constant cough, we may prescribe antihistamines, which can relieve allergy symptoms, like coughing and antacids to neutralize the stomach acid irritating your throat. […] Your chronic cough could also be a side effect of drugs used to treat high blood pressure. You and your provider can talk about trying other blood pressure medications if youre having this side effect. […] Your provider may recommend behavioral cough suppression therapy (BCST). Our specialized therapists teach you how to control your urge to cough with behavioral techniques. Your treatment plan may combine BCST and medication to suppress your chronic cough. […] Our chronic cough clinic offers the newest tests and innovative treatments if traditional therapies arent making your symptoms go away. We offer: Lab tests to see if there are bacteria in your blood or phlegm. Lung function tests, like spirometry, to check how well your lungs are working. Imaging tests, like chest X-rays, CT scans, MRIs, ultrasound and nuclear testing to get a closer, more detailed look inside your body. […] You dont have to live with it. You can get relief. Cleveland Clinic healthcare providers are here to help you find relief by building a personalized treatment plan that will silence your chronic cough.

• #44 Patient education: Chronic cough in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-cough-in-adults-beyond-the-basics

  Eosinophilic bronchitis is treated with inhaled glucocorticoids. […] If, after a thorough evaluation, the cause of your cough cannot be determined and the cough persists, a medication that suppresses your cough may be recommended. Possible options include: Nonprescription cough medicines that contain dextromethorphan (Delsym) may help suppress the cough reflex. […] Gabapentin or pregabalin, which are drugs more commonly used to ameliorate chronic pain by blocking nerve impulses, may be helpful in some patients with chronic cough.

• #45 Patient education: Chronic cough in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-cough-in-adults-beyond-the-basics

  Eosinophilic bronchitis is treated with inhaled glucocorticoids. […] If, after a thorough evaluation, the cause of your cough cannot be determined and the cough persists, a medication that suppresses your cough may be recommended. Possible options include: Nonprescription cough medicines that contain dextromethorphan (Delsym) may help suppress the cough reflex. […] Gabapentin or pregabalin, which are drugs more commonly used to ameliorate chronic pain by blocking nerve impulses, may be helpful in some patients with chronic cough.

• #46 Chronic Cough: Causes, Treatment, and More

  https://www.healthline.com/health/chronic-cough

  Drugs used to treat asthma can include inhaled steroids and bronchodilators, which require a prescription. These medicines bring down swelling in the airways and widen narrowed air passages to help you breathe more easily. […] Antibiotics can help treat pneumonia or other bacterial infections, such as whooping cough. […] Decongestants can dry up secretions. Antihistamines and steroid nasal sprays can block the allergic response that causes mucus production and help bring down swelling in your nasal passages. […] Speech therapy may be effective in lowering the severity of a chronic cough. Your doctor can provide you with a referral to a speech therapist. […] Cough medicines that contain dextromethorphan (Mucinex, Robitussin) may help relax the cough reflex. […] If OTC options don’t help, your doctor may prescribe a medication, such as benzonatate (Tessalon). This numbs the cough reflex. […] Researchers are continuing to study new treatments that may relieve chronic cough in people who haven’t responded to other therapies. This is likely to lead to more effective treatments in the future.

• #47 Chronic Cough: Symptoms, Causes, 5 Types & 5 Prevention Tips

  https://www.medicinenet.com/chronic_cough/article.htm

  Chronic cough is a cough that persists over time. Chronic cough is not a disease in itself, but rather a symptom of an underlying condition. […] Treatment for chronic cough is to identify the cause and treat it. […] The treatment of chronic cough is directed at the cause. Symptoms may be relieved with over-the-counter (OTC) cough medicines containing guaifenesin and/or dextromethorphan (these can be found as cough syrups in tablet form). […] The following are treatments for chronic cough caused by medications, conditions, or diseases. […] In severe cases of chronic cough, a healthcare professional may prescribe codeine or other similar narcotic medications, which are effective as cough suppressants. […] Infections: Bacterial pneumonia and bronchitis are typically treated with antibiotics such as cephalosporins, azithromycin (Zithromax), and other antibiotics.

• #48 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Antibiotics. If a bacterial, fungal or mycobacterial infection is causing your chronic cough, your healthcare professional may prescribe antibiotic medicines for the infection. […] Acid blockers. When lifestyle changes don’t take care of acid reflux, you may be treated with medicines that block acid production. Some people need surgery to resolve the problem. […] Your healthcare professional works to find the cause of your cough and the best treatment for you. During that time, your healthcare professional also may prescribe a medicine to reduce coughing, called a cough suppressant. Cough suppressants are not recommended for children. […] Cough and cold medicines available without a prescription treat the symptoms of coughs and colds not the underlying disease. Research suggests that these medicines don’t work any better than no medicine at all. These medicines are not recommended for children because of potentially serious side effects, including fatal overdoses in children younger than 2 years old. […] Don’t use over-the-counter cough and cold medicines, except for fever reducers and pain relievers, to treat coughs and colds in children younger than 6 years old. Also, avoid use of these medicines for children younger than 12 years old. Check with your healthcare professional for guidance.

• #49 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Antibiotics. If a bacterial, fungal or mycobacterial infection is causing your chronic cough, your healthcare professional may prescribe antibiotic medicines for the infection. […] Acid blockers. When lifestyle changes don’t take care of acid reflux, you may be treated with medicines that block acid production. Some people need surgery to resolve the problem. […] Your healthcare professional works to find the cause of your cough and the best treatment for you. During that time, your healthcare professional also may prescribe a medicine to reduce coughing, called a cough suppressant. Cough suppressants are not recommended for children. […] Cough and cold medicines available without a prescription treat the symptoms of coughs and colds not the underlying disease. Research suggests that these medicines don’t work any better than no medicine at all. These medicines are not recommended for children because of potentially serious side effects, including fatal overdoses in children younger than 2 years old. […] Don’t use over-the-counter cough and cold medicines, except for fever reducers and pain relievers, to treat coughs and colds in children younger than 6 years old. Also, avoid use of these medicines for children younger than 12 years old. Check with your healthcare professional for guidance.

• #50 Updates in Treatment of Adults With Chronic Cough

  https://www.ajmc.com/view/updates-in-treatment-of-adults-with-chronic-cough

  Results of a systematic review by Chamberlain et al found 2 to 4 sessions of speech pathology that included education, cough suppression techniques, breathing exercises, laryngeal hygiene, and counseling resulted in decreased cough frequency, improved cough severity, and positive benefits on cough-related QOL. […] Pharmacologic treatment for chronic cough has limited efficacy, resulting in decreased quality of life (QOL) for many patients affected. […] The efficacy of gabapentin was evaluated in a 10-week randomized controlled trial (N = 62) in patients with RCC, and results indicated that gabapentin (1800 mg/day) significantly improved LCQ scores compared with placebo (P = .004). […] It also decreased cough severity scores (P = .029) and objective cough frequency (P = .028) by week 8.

• #51 Management of chronic refractory cough in adults

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7501523/

  Gabapentin and pregabalin are gamma aminobutyric acid (GABA) analogs that bind to the voltage-gated calcium channels and inhibit centrally neurotransmitter release. […] Gabapentin is recommended by current guidelines as a potential pharmacologic treatment for CRC. […] In conclusion, there are few effective treatments for cough with an acceptable therapeutic ratio; more selective agents with a more favorable side effect profile are needed. […] Additional information regarding neurobiology has introduced a number of novel pharmacological treatment options, including drugs targeting the P23 receptor, which seems to be the most promising.

• #52 Updates in Treatment of Adults With Chronic Cough

  https://www.ajmc.com/view/updates-in-treatment-of-adults-with-chronic-cough

  Results of a systematic review by Chamberlain et al found 2 to 4 sessions of speech pathology that included education, cough suppression techniques, breathing exercises, laryngeal hygiene, and counseling resulted in decreased cough frequency, improved cough severity, and positive benefits on cough-related QOL. […] Pharmacologic treatment for chronic cough has limited efficacy, resulting in decreased quality of life (QOL) for many patients affected. […] The efficacy of gabapentin was evaluated in a 10-week randomized controlled trial (N = 62) in patients with RCC, and results indicated that gabapentin (1800 mg/day) significantly improved LCQ scores compared with placebo (P = .004). […] It also decreased cough severity scores (P = .029) and objective cough frequency (P = .028) by week 8.

• #53 Updates in Treatment of Adults With Chronic Cough

  https://www.ajmc.com/view/updates-in-treatment-of-adults-with-chronic-cough

  Current CHEST guidelines recommend a trial of gabapentin as long as patients are educated on the potential for AEs and the risk-benefit profile along with a reassessment of risk-benefit at 6 months before continuing therapy. […] The lack of efficacy of traditional antitussive agents combined with an improved understanding of the neurobiology of the cough reflex has led to an increased focus on the development of new agents to address this treatment gap. […] The new chronic cough agents target specific receptors or channels in the peripheral sensory neurons with the goal of reduced central nervous system AEs and control of hypersensitivity while reserving the protective cough response. […] Gefapixant (MK-7264/AF-219) is a novel, first-in-class, nonnarcotic, selective antagonist of the P2X3 receptor currently in clinical trials evaluating its safety and efficacy for treatment of chronic cough.

• #54 Chronic Cough: Evaluation and Management | AAFP

  https://www.aafp.org/pubs/afp/issues/2017/1101/p575.html

  Neuromodulators have shown some benefit in randomized trials based on the hypothesis that refractory chronic cough may be due to hypersensitivity of the cough reflex caused by peripheral (afferent limb of the cough reflex) and central mechanisms (central sensitization). […] Gabapentin (Neurontin, 1,800 mg per day), which improved symptoms within four weeks; pregabalin (Lyrica, 300 mg per day) in conjunction with speech therapy, which showed greater improvement vs. placebo with speech therapy; and speech and language therapy alone. […] Chronic cough in children younger than 15 years is defined as cough lasting more than four weeks. […] The most common causes of chronic cough in children six to 14 years of age are asthma, protracted bacterial bronchitis, and UACS. […] Treatment consists of a two-week course of an appropriate antibiotic, such as amoxicillin/clavulanate (Augmentin).

• #55 Current Management of Chronic Cough and Emerging Therapies

  https://www.ajmc.com/view/current-management-of-chronic-cough-and-emerging-therapies

  Gabapentin is another neuromodulatory drug that has been shown to improve cough, but similar to opiates, there is a reoccurrence of cough after the therapy is stopped. […] The last neuromodulatory drug being used is amitriptyline, which was studied in 10 mg at night. […] Novel compounds being studied are looking to address cough hypersensitivity in chronic cough, and they have a wide range of targets. […] We are actually at an exciting threshold in terms of the neuropharmacology for the new agents that we are likely to see in the next year or so made available to us for treating our patients, he concluded.

• #56 Current Management of Chronic Cough and Emerging Therapies

  https://www.ajmc.com/view/current-management-of-chronic-cough-and-emerging-therapies

  Chronic cough is a problem that can have a major impact on quality of life for patients. […] There are emerging therapies that could change treatment for these patients. […] Patients with a chronic cough usually try different treatments, including all of the over-the-counter medications, and they have moved onto complimentary or alternative treatments, he explained. […] Currently, clinicians use different neuromodulatory agents to treat chronic cough, and opiates are the most commonly used agent, because we know they work very well. […] Morphine doses of 5 to 10 mg twice a day (BID) and codeine doses of 60 mg per day have been used in patients in different studies, Sundar explained. […] Dextromethorphan is another widely available medication and can be found in more than 100 over-the-counter treatments.

• #57 Management of chronic refractory cough in adults

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7501523/

  Gabapentin and pregabalin are gamma aminobutyric acid (GABA) analogs that bind to the voltage-gated calcium channels and inhibit centrally neurotransmitter release. […] Gabapentin is recommended by current guidelines as a potential pharmacologic treatment for CRC. […] In conclusion, there are few effective treatments for cough with an acceptable therapeutic ratio; more selective agents with a more favorable side effect profile are needed. […] Additional information regarding neurobiology has introduced a number of novel pharmacological treatment options, including drugs targeting the P23 receptor, which seems to be the most promising.

• #58 Treatment of Unexplained Chronic Cough

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5831652/

  Unexplained chronic cough (UCC) causes significant impairments in quality of life. Effective assessment and treatment approaches are needed for UCC. […] The evidence supporting the diagnosis and management of UCC is limited. UCC requires further study to establish agreed terminology and the optimal methods of investigation using established criteria for intervention fidelity. Speech pathology-based cough suppression is suggested as a treatment option for UCC. […] In adult patients with unexplained chronic cough, we suggest a therapeutic trial of multimodality speech pathology therapy. […] In adult patients with unexplained chronic cough, we suggest a therapeutic trial of gabapentin as long as the potential side effects and the risk-benefit profile are discussed with patients before use of the medication, and there is a reassessment of the risk-benefit profile at 6 months before continuing the drug.

• #59 Management of chronic refractory cough in adults

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7501523/

  Speech pathology can be combined with a neuromodulator to give an enhanced treatment response of longer duration suggesting that non-pharmacologic treatment may play a key role in the management of CRC. […] The two most influential guidelines for the management of cough, and particularly CRC, are: 1) those developed and updated by the ACCP, and 2) those developed by the ERS. […] According to current ERS guidelines, multi-component physiotherapy/speech and language therapy interventions should be considered for CRC patients who wish an alternative to drug treatment. […] Despite the efficacy and advantages of speech pathology intervention, there is limited guidance in the literature as to when patients should be referred for treatment. […] Pathological mechanisms may affect central and peripheral neuromodulators or cause a hypersensitivity of the cough reflex.

• #60 Get Chronic Cough Treatment | Cleveland Clinic

  https://my.clevelandclinic.org/services/chronic-cough-treatment

  If allergies are contributing to your constant cough, we may prescribe antihistamines, which can relieve allergy symptoms, like coughing and antacids to neutralize the stomach acid irritating your throat. […] Your chronic cough could also be a side effect of drugs used to treat high blood pressure. You and your provider can talk about trying other blood pressure medications if youre having this side effect. […] Your provider may recommend behavioral cough suppression therapy (BCST). Our specialized therapists teach you how to control your urge to cough with behavioral techniques. Your treatment plan may combine BCST and medication to suppress your chronic cough. […] Our chronic cough clinic offers the newest tests and innovative treatments if traditional therapies arent making your symptoms go away. We offer: Lab tests to see if there are bacteria in your blood or phlegm. Lung function tests, like spirometry, to check how well your lungs are working. Imaging tests, like chest X-rays, CT scans, MRIs, ultrasound and nuclear testing to get a closer, more detailed look inside your body. […] You dont have to live with it. You can get relief. Cleveland Clinic healthcare providers are here to help you find relief by building a personalized treatment plan that will silence your chronic cough.

• #61 Chronic Cough | Condition | UT Southwestern Medical Center

  https://utswmed.org/conditions-treatments/chronic-cough/

  UT Southwestern Medical Center provides expert care for people who have a chronic cough and other conditions affecting the airways, larynx (voice box), throat, and lungs. Using the latest technology, we work to evaluate, diagnose, and treat the underlying causes of chronic cough. […] Our multidisciplinary approach often combines the expertise of fellowship-trained laryngologists, pulmonologists, speech-language pathologists, allergists, and other care professionals focused on voice, throat, and lung conditions. Our physicians, therapists, and researchers are widely recognized as experts in the accurate diagnosis and effective treatment of chronic cough. […] Treatment for chronic cough involves remedying the underlying cause, and options include: […] Cough suppressant medications to control the cough […] Cough suppression techniques, taught by our speech-language pathologists, to help reduce the severity and frequency of the cough.

• #62 Chronic Cough | Conditions & Treatments | UR Medicine

  https://www.urmc.rochester.edu/conditions-and-treatments/chronic-cough

  Chronic cough often leads to laryngeal hypersensitivity, which means the larynx (also known as the voice box) is especially sensitive and irritated. […] Our Speech-Language Pathologists (SLP) have specialty training and expertise in chronic cough. We will complete a personalized assessment of your coughing, breathing, and voice in order to diagnose you correctly. […] Your provider will treat your cough based on the condition it relates to. Treatment may include: […] Voice therapy […] Breathing techniques […] Medications including antibiotics, decongestants, or steroids.

• #63 Get Chronic Cough Treatment | Cleveland Clinic

  https://my.clevelandclinic.org/services/chronic-cough-treatment

  If allergies are contributing to your constant cough, we may prescribe antihistamines, which can relieve allergy symptoms, like coughing and antacids to neutralize the stomach acid irritating your throat. […] Your chronic cough could also be a side effect of drugs used to treat high blood pressure. You and your provider can talk about trying other blood pressure medications if youre having this side effect. […] Your provider may recommend behavioral cough suppression therapy (BCST). Our specialized therapists teach you how to control your urge to cough with behavioral techniques. Your treatment plan may combine BCST and medication to suppress your chronic cough. […] Our chronic cough clinic offers the newest tests and innovative treatments if traditional therapies arent making your symptoms go away. We offer: Lab tests to see if there are bacteria in your blood or phlegm. Lung function tests, like spirometry, to check how well your lungs are working. Imaging tests, like chest X-rays, CT scans, MRIs, ultrasound and nuclear testing to get a closer, more detailed look inside your body. […] You dont have to live with it. You can get relief. Cleveland Clinic healthcare providers are here to help you find relief by building a personalized treatment plan that will silence your chronic cough.

• #64 Reddit – The heart of the internet

  https://www.reddit.com/r/AMA/comments/1hi30rm/i_successfully_treat_chronic_cough_every_day/

  I successfully treat chronic cough every day without side effects! Im the leading expert in cognitive behavioral cough suppression therapy and developer of a new treatment for chronic cough. […] My work focuses on understanding and treating refractory or unexplained chronic cough (RCC/UCC) that stubborn, persistent cough that just wont go away. […] One of my most exciting projects is Cough Desensitization Therapy (CDT) a new treatment that combines cough suppression techniques with capsaicin inhalation (yes, thats the spicy stuff in chili peppers) to reduce cough sensitivity. […] Early results from my telehealth-based group therapy sessions on behavioral cough suppression therapy are also promising, with over 50% of participants reporting their cough is gone or almost gone! […] Im also advising on the development of the first digital therapeutic (DTx) for chronic cough, and also cough management wellness techniques available on the cough monitoring smartphone app – CoughPro – which is available globally.

• #65 Updates in Treatment of Adults With Chronic Cough

  https://www.ajmc.com/view/updates-in-treatment-of-adults-with-chronic-cough

  Results of a systematic review by Chamberlain et al found 2 to 4 sessions of speech pathology that included education, cough suppression techniques, breathing exercises, laryngeal hygiene, and counseling resulted in decreased cough frequency, improved cough severity, and positive benefits on cough-related QOL. […] Pharmacologic treatment for chronic cough has limited efficacy, resulting in decreased quality of life (QOL) for many patients affected. […] The efficacy of gabapentin was evaluated in a 10-week randomized controlled trial (N = 62) in patients with RCC, and results indicated that gabapentin (1800 mg/day) significantly improved LCQ scores compared with placebo (P = .004). […] It also decreased cough severity scores (P = .029) and objective cough frequency (P = .028) by week 8.

• #66 Updates in Treatment of Adults With Chronic Cough

  https://www.ajmc.com/view/updates-in-treatment-of-adults-with-chronic-cough

  Current CHEST guidelines recommend a trial of gabapentin as long as patients are educated on the potential for AEs and the risk-benefit profile along with a reassessment of risk-benefit at 6 months before continuing therapy. […] The lack of efficacy of traditional antitussive agents combined with an improved understanding of the neurobiology of the cough reflex has led to an increased focus on the development of new agents to address this treatment gap. […] The new chronic cough agents target specific receptors or channels in the peripheral sensory neurons with the goal of reduced central nervous system AEs and control of hypersensitivity while reserving the protective cough response. […] Gefapixant (MK-7264/AF-219) is a novel, first-in-class, nonnarcotic, selective antagonist of the P2X3 receptor currently in clinical trials evaluating its safety and efficacy for treatment of chronic cough.

• #67 Updates in Treatment of Adults With Chronic Cough

  https://www.ajmc.com/view/updates-in-treatment-of-adults-with-chronic-cough

  Current CHEST guidelines recommend a trial of gabapentin as long as patients are educated on the potential for AEs and the risk-benefit profile along with a reassessment of risk-benefit at 6 months before continuing therapy. […] The lack of efficacy of traditional antitussive agents combined with an improved understanding of the neurobiology of the cough reflex has led to an increased focus on the development of new agents to address this treatment gap. […] The new chronic cough agents target specific receptors or channels in the peripheral sensory neurons with the goal of reduced central nervous system AEs and control of hypersensitivity while reserving the protective cough response. […] Gefapixant (MK-7264/AF-219) is a novel, first-in-class, nonnarcotic, selective antagonist of the P2X3 receptor currently in clinical trials evaluating its safety and efficacy for treatment of chronic cough.

• #68 Updates in Treatment of Adults With Chronic Cough

  https://www.ajmc.com/view/updates-in-treatment-of-adults-with-chronic-cough

  Current CHEST guidelines recommend a trial of gabapentin as long as patients are educated on the potential for AEs and the risk-benefit profile along with a reassessment of risk-benefit at 6 months before continuing therapy. […] The lack of efficacy of traditional antitussive agents combined with an improved understanding of the neurobiology of the cough reflex has led to an increased focus on the development of new agents to address this treatment gap. […] The new chronic cough agents target specific receptors or channels in the peripheral sensory neurons with the goal of reduced central nervous system AEs and control of hypersensitivity while reserving the protective cough response. […] Gefapixant (MK-7264/AF-219) is a novel, first-in-class, nonnarcotic, selective antagonist of the P2X3 receptor currently in clinical trials evaluating its safety and efficacy for treatment of chronic cough.

• #69

  https://www.kch.nhs.uk/news/drug-hope-for-millions-of-people-living-with-chronic-cough/

  The new treatment trialled at Kings College Hospital, has been found to ease the symptoms of chronic cough by up to 60%. […] A respiratory consultant at Kings College Hospital Foundation Trust published a study in The Lancet earlier this year about the new drug Gefapixant, which has been found to ease the symptoms of chronic cough by up to 60%. […] Gefapixant, which is taken orally, was tested over two clinical trials Cough 1 and Cough 2 that lasted 52 weeks. In both studies the drug resulted in a reduction in coughing for up to six months, the research suggests. […] The drug works by blocking receptors in the sensory nerves that control coughing and reduces their hypersensitivity. […] Gefapixant works within days of being administered and has been shown to be effective in nearly 70% of trial patients.

• #70 Camlipixant: A New Treatment Option for Refractory Chronic Cough? – touchRESPIRATORY

  https://touchrespiratory.com/chronic-cough/journal-articles/camlipixant-a-new-treatment-option-for-refractory-chronic-cough/

  Treatments for chronic refractory cough that act centrally are not particularly effective and are often accompanied by adverse effects. […] Camlipixant, another drug in this class, is currently being studied in a phase III trial. […] The treatment of cases of RCC and UCC is challenging. A speech pathology approach, which uses techniques similar to those used to treat hyperfunctional voice disorders and vocal cord dysfunction, is successful in approximately half of the cases. […] The pharmacologic treatment of these conditions is challenging. […] The American College of Chest Physicians suggests the use of speech pathology therapy techniques and gabapentin for the treatment of RCC and UCC. […] The European Respiratory Society chronic cough guidelines also recommend trials of morphine, gabapentin or pregabalin in RCC.

• #71

  https://www.kch.nhs.uk/news/drug-hope-for-millions-of-people-living-with-chronic-cough/

  The new treatment trialled at Kings College Hospital, has been found to ease the symptoms of chronic cough by up to 60%. […] A respiratory consultant at Kings College Hospital Foundation Trust published a study in The Lancet earlier this year about the new drug Gefapixant, which has been found to ease the symptoms of chronic cough by up to 60%. […] Gefapixant, which is taken orally, was tested over two clinical trials Cough 1 and Cough 2 that lasted 52 weeks. In both studies the drug resulted in a reduction in coughing for up to six months, the research suggests. […] The drug works by blocking receptors in the sensory nerves that control coughing and reduces their hypersensitivity. […] Gefapixant works within days of being administered and has been shown to be effective in nearly 70% of trial patients.

• #72

  https://www.kch.nhs.uk/news/drug-hope-for-millions-of-people-living-with-chronic-cough/

  The new treatment trialled at Kings College Hospital, has been found to ease the symptoms of chronic cough by up to 60%. […] A respiratory consultant at Kings College Hospital Foundation Trust published a study in The Lancet earlier this year about the new drug Gefapixant, which has been found to ease the symptoms of chronic cough by up to 60%. […] Gefapixant, which is taken orally, was tested over two clinical trials Cough 1 and Cough 2 that lasted 52 weeks. In both studies the drug resulted in a reduction in coughing for up to six months, the research suggests. […] The drug works by blocking receptors in the sensory nerves that control coughing and reduces their hypersensitivity. […] Gefapixant works within days of being administered and has been shown to be effective in nearly 70% of trial patients.

• #73

  https://www.kch.nhs.uk/news/drug-hope-for-millions-of-people-living-with-chronic-cough/

  These global trials have demonstrated that Gefapixant has the potential to significantly improve the quality of life for patients who struggle with chronic coughing and its distressing effects. […] As effective treatments for cough are currently an unmet clinical need and with no new therapies being approved in over 50 years, Gefapixant offers new hope to thousands of people. […] Patty hopes that new drugs like Gefapixant can be made available to people living with chronic cough.

• #74 A cough that won’t go away: Evaluation and treatment in 2 patients | Cleveland Clinic Journal of Medicine

  https://www.ccjm.org/content/87/2/83

  A cough that wont go away: Evaluation and treatment in 2 patients […] A 65-year-old man presents with a dry, nonproductive cough, which he has had for 10 months. He describes it as very intrusive, as it limits his effectiveness in his work. […] A second patient, a 48-year-old woman, presents with a similar history of nonproductive cough for 8 months. […] While all of the above are important in the diagnosis of chronic cough, collecting an extensive history is a crucial first step to rule out the most common causes of chronic cough and should always be done. […] These drugs are a common treatment for hypertension and are well known to cause a persistent dry cough. […] Common diagnostic tests such as chest radiography, nasal endoscopy, laryngoscopy, spirometry with bronchodilator testing, and exhaled nitric oxide measurement can also be used to detect some of the less apparent causes of chronic cough. […] Chest radiography will not reveal the most common causes of cough, but it is important in detecting foreign body aspiration and lung diseases such as pneumonia, lung cancer, and tuberculosis. […] Cough from postnasal drip, otherwise known as upper airway cough syndrome (UACS), is the most common cause of chronic cough seen in respiratory clinics, contributing to 26% to 87% of US cases. […] Neuromodulators are most often the first-line treatment for unexplained chronic cough. […] Behavioral cough suppression therapy is a good option for patients with unexplained chronic cough and is recommended by current guidelines. […] Superior laryngeal nerve block is an emerging office-based treatment, but it is unknown how many injections are needed for cough suppression. […] Botulinum toxin type A is another agent thought to lessen laryngeal hypersensitivity and hyperactivity. […] Morphine and codeine have a long history of use as centrally acting cough suppressants. […] After discussing treatment options with the patient, we decide to start a trial of gabapentin. […] If the patient does not respond to neuromodulators or wishes to pursue other options, it may be beneficial to recommend a trial of an opioid, behavioral cough suppression therapy, laryngeal botulinum toxin injections, or superior laryngeal nerve block. […] Research into novel treatments for refractory chronic cough is focused on blocking cough arising from various etiologies while minimizing adverse effects. […] Unexplained chronic cough (also known as chronic refractory cough) is common, imposes a large healthcare burden, and can adversely affect quality of life. […] The most common causes of chronic cough include asthma (and other lung diseases), UACS, and GERD. Testing for these underlying conditions should be pursued before establishing a diagnosis of unexplained chronic cough. […] Neuromodulators have proved to be efficacious in the treatment of unexplained chronic cough and should be first-line therapy. […] Behavioral cough suppression therapy administered by a speech pathologist also shows efficacy and should be offered either in conjunction with other treatments or by itself. […]

• #75 A cough that won’t go away: Evaluation and treatment in 2 patients | Cleveland Clinic Journal of Medicine

  https://www.ccjm.org/content/87/2/83

  A cough that wont go away: Evaluation and treatment in 2 patients […] A 65-year-old man presents with a dry, nonproductive cough, which he has had for 10 months. He describes it as very intrusive, as it limits his effectiveness in his work. […] A second patient, a 48-year-old woman, presents with a similar history of nonproductive cough for 8 months. […] While all of the above are important in the diagnosis of chronic cough, collecting an extensive history is a crucial first step to rule out the most common causes of chronic cough and should always be done. […] These drugs are a common treatment for hypertension and are well known to cause a persistent dry cough. […] Common diagnostic tests such as chest radiography, nasal endoscopy, laryngoscopy, spirometry with bronchodilator testing, and exhaled nitric oxide measurement can also be used to detect some of the less apparent causes of chronic cough. […] Chest radiography will not reveal the most common causes of cough, but it is important in detecting foreign body aspiration and lung diseases such as pneumonia, lung cancer, and tuberculosis. […] Cough from postnasal drip, otherwise known as upper airway cough syndrome (UACS), is the most common cause of chronic cough seen in respiratory clinics, contributing to 26% to 87% of US cases. […] Neuromodulators are most often the first-line treatment for unexplained chronic cough. […] Behavioral cough suppression therapy is a good option for patients with unexplained chronic cough and is recommended by current guidelines. […] Superior laryngeal nerve block is an emerging office-based treatment, but it is unknown how many injections are needed for cough suppression. […] Botulinum toxin type A is another agent thought to lessen laryngeal hypersensitivity and hyperactivity. […] Morphine and codeine have a long history of use as centrally acting cough suppressants. […] After discussing treatment options with the patient, we decide to start a trial of gabapentin. […] If the patient does not respond to neuromodulators or wishes to pursue other options, it may be beneficial to recommend a trial of an opioid, behavioral cough suppression therapy, laryngeal botulinum toxin injections, or superior laryngeal nerve block. […] Research into novel treatments for refractory chronic cough is focused on blocking cough arising from various etiologies while minimizing adverse effects. […] Unexplained chronic cough (also known as chronic refractory cough) is common, imposes a large healthcare burden, and can adversely affect quality of life. […] The most common causes of chronic cough include asthma (and other lung diseases), UACS, and GERD. Testing for these underlying conditions should be pursued before establishing a diagnosis of unexplained chronic cough. […] Neuromodulators have proved to be efficacious in the treatment of unexplained chronic cough and should be first-line therapy. […] Behavioral cough suppression therapy administered by a speech pathologist also shows efficacy and should be offered either in conjunction with other treatments or by itself. […]

• #76 Reddit – The heart of the internet

  https://www.reddit.com/r/AMA/comments/1hi30rm/i_successfully_treat_chronic_cough_every_day/

  I successfully treat chronic cough every day without side effects! Im the leading expert in cognitive behavioral cough suppression therapy and developer of a new treatment for chronic cough. […] My work focuses on understanding and treating refractory or unexplained chronic cough (RCC/UCC) that stubborn, persistent cough that just wont go away. […] One of my most exciting projects is Cough Desensitization Therapy (CDT) a new treatment that combines cough suppression techniques with capsaicin inhalation (yes, thats the spicy stuff in chili peppers) to reduce cough sensitivity. […] Early results from my telehealth-based group therapy sessions on behavioral cough suppression therapy are also promising, with over 50% of participants reporting their cough is gone or almost gone! […] Im also advising on the development of the first digital therapeutic (DTx) for chronic cough, and also cough management wellness techniques available on the cough monitoring smartphone app – CoughPro – which is available globally.

• #77

  https://link.springer.com/article/10.1007/s40136-019-00239-9

  The TRPV1 antagonists, SB-705498 and XEN-D0501, have shown marked reduction in capsaicin-induced cough reflex sensitivity but failed to reduce cough frequency in chronic cough patients. […] Gefapixant (MK-7264), previously known as AF-219, is a P2X3 receptor antagonist recently shown to reduce cough frequency in a small placebo-controlled, crossover study of patients with unexplained chronic cough. […] Currently, this compound represents the most promising therapeutic target in development. […] Treatment of chronic cough with amitriptyline is reported to reduce cough, and in an open-label study of treatment for 10 days, improvements in cough frequency and severity when compared with codeine were reported. […] The NK1R antagonist, aprepitant, has been shown to reduce cough in patients with lung cancer.

• #78 Chronic Cough: 8 Causes, Treatment, and More

  https://www.health.com/condition/copd/8-causes-of-chronic-cough-and-what-to-do-about-it

  Causes of a chronic cough, which persists for more than eight weeks, include air pollution, asthma or allergies, chronic obstructive pulmonary disease (COPD), and gastroesophageal reflux disease (GERD). Smoking tobacco and marijuana (pot) has been shown to cause a persistent cough. […] Treating a chronic cough will depend on the underlying cause. The options available to you will be specific to your individual case. […] Identifying and avoiding allergens or taking allergy medications, for example, can resolve allergy-related chronic coughing. A healthcare provider may also advise treatments to manage the coughing if it cannot be resolved. […] A few home remedies exist to treat or manage a chronic cough. You may try the following: Avoid or limit exposure to allergens or irritants, including tobacco smoke. Consume cough drops, hard candies, or honey to decrease discomfort from a sore throat. Drink plenty of fluids to thin mucus that might make you cough. Use a humidifier to moisten the air in your home. […] It’s important to get a chronic cough checked out if you have symptoms that last two months or longer. Only a healthcare provider can confirm what’s going on with a long-lasting cough and recommend what can give you relief.

• #79 Get Chronic Cough Treatment | Cleveland Clinic

  https://my.clevelandclinic.org/services/chronic-cough-treatment

  If your cough lingers for more than eight weeks, its time to get help. Cleveland Clinics pulmonologists (lung specialists) are here to help you figure out why you cant stop coughing. Theyll take time to listen to your concerns and design a personalized treatment plan help you get relief. […] Different things can cause your chronic cough. You can have health issues like allergies or gastroesophageal reflux disease (GERD, or acid reflux). Or something environmental and lifestyle-related could trigger it like smoking or medications youre taking. In rare cases, chronic cough can be a sign of lung cancer. […] Once we figure out whats causing your cough, well work with you to create a custom treatment plan that keeps you in mind. […] Sometimes you can ease a cough with lifestyle changes. Your provider may recommend you: Stop smoking. Avoid foods that trigger acid reflux. Sleep with your head propped up on pillows. Avoid allergens when possible. Drink plenty of water.

• #80 Chronic Cough: Practice Essentials, Mechanism of Cough, Causes of Chronic Cough

  https://emedicine.medscape.com/article/1048560-overview

  The management of chronic cough presents a challenge for the clinician. Typically defined as a cough that persists for longer than 8 weeks, this is the most common presenting symptom in adults who seek medical treatment in an ambulatory setting. Chronic cough is estimated to occur in up to 40% of the population. […] A multidisciplinary approach is often needed, with the primary care provider coordinating care with appropriate referrals to the otolaryngologist, pulmonologist, or both, as appropriate. […] Management should begin with cessation of smoking or angiotensin-converting enzyme (ACE) inhibitor use in those patients whose history indicates such action. Most patients have a resolution of their cough within 4 weeks of smoking cessation. Cough related to ACE inhibitor use usually subsides within 2 weeks, but the median time has been reported to be 26 days.

• #81 Cough: Causes, Emergency Symptoms, Treatment, Prevention

  https://www.healthline.com/health/cough

  If you can, avoid anyone with a contagious illness such as bronchitis. This will reduce your chances of coming into contact with germs. […] If you have existing medical conditions that increase your chances of developing a cough, such as GERD or asthma, ask a doctor about different management strategies. Once you manage your condition, you may find that your cough disappears or becomes much less frequent.

• #82 Cough: Causes, Emergency Symptoms, Treatment, Prevention

  https://www.healthline.com/health/cough

  A cough can be treated in a variety of ways, depending on the cause. Healthy adults will mostly be able to treat their coughs with home remedies and self-care. […] A cough that results from a virus cant be treated with antibiotics. You can soothe it in the following ways instead: Keep hydrated by drinking plenty of water. Elevate your head with extra pillows when sleeping. Use cough drops to soothe your throat. Gargle with warm salt water regularly to remove mucus and soothe your throat. Avoid irritants, including smoke and dust. Add honey or ginger to hot tea to relieve your cough and clear your airway. Use decongestant sprays to unblock your nose and ease breathing. […] Typically, medical care will involve a doctor looking down your throat, listening to your cough, and asking about any other symptoms. If your cough is likely due to a bacterial infection, the doctor will prescribe oral antibiotics. They may also prescribe either cough suppressants that contain codeine or expectorant cough syrups.

• #83 Chronic Cough Treatments | Northwestern Medicine

  https://www.nm.org/conditions-and-care-areas/pulmonary/chronic-cough/treatments

  Treatment for chronic cough will depend on the underlying medical condition thats causing it. Once a diagnosis is made, your physician may recommend one or more of these treatments: […] Quitting smoking […] Antihistamines or decongestants for postnasal drip or allergies […] Acid blocking medication for GERD […] Inhalant medications for asthma […] Alternate medications for hypertension or heart failure to replace ace inhibitors […] Surgery for tumors or blockages […] Lifestyle changes, including: Drinking more water […] Humidifying your workplace and bedroom […] Raising the head of your bed or using more pillows when sleeping. […] Medications […] Surgery.

• #84 Get Chronic Cough Treatment | Cleveland Clinic

  https://my.clevelandclinic.org/services/chronic-cough-treatment

  If your cough lingers for more than eight weeks, its time to get help. Cleveland Clinics pulmonologists (lung specialists) are here to help you figure out why you cant stop coughing. Theyll take time to listen to your concerns and design a personalized treatment plan help you get relief. […] Different things can cause your chronic cough. You can have health issues like allergies or gastroesophageal reflux disease (GERD, or acid reflux). Or something environmental and lifestyle-related could trigger it like smoking or medications youre taking. In rare cases, chronic cough can be a sign of lung cancer. […] Once we figure out whats causing your cough, well work with you to create a custom treatment plan that keeps you in mind. […] Sometimes you can ease a cough with lifestyle changes. Your provider may recommend you: Stop smoking. Avoid foods that trigger acid reflux. Sleep with your head propped up on pillows. Avoid allergens when possible. Drink plenty of water.

• #85 Get Chronic Cough Treatment | Cleveland Clinic

  https://my.clevelandclinic.org/services/chronic-cough-treatment

  If your cough lingers for more than eight weeks, its time to get help. Cleveland Clinics pulmonologists (lung specialists) are here to help you figure out why you cant stop coughing. Theyll take time to listen to your concerns and design a personalized treatment plan help you get relief. […] Different things can cause your chronic cough. You can have health issues like allergies or gastroesophageal reflux disease (GERD, or acid reflux). Or something environmental and lifestyle-related could trigger it like smoking or medications youre taking. In rare cases, chronic cough can be a sign of lung cancer. […] Once we figure out whats causing your cough, well work with you to create a custom treatment plan that keeps you in mind. […] Sometimes you can ease a cough with lifestyle changes. Your provider may recommend you: Stop smoking. Avoid foods that trigger acid reflux. Sleep with your head propped up on pillows. Avoid allergens when possible. Drink plenty of water.

• #86 Home remedies for cough

  https://www.medicalnewstoday.com/articles/322394

  A number of home remedies, such as honey and saltwater, may help manage cough symptoms. If home remedies do not help, over-the-counter and prescription medications are available. […] This article reviews natural remedies that may help treat a cough. […] People who want to try natural remedies to treat their cough should consider researching sources and brands. Additionally, some herbs and supplements can interfere with medications, which may result in unwanted side effects. It is best to consult a doctor before taking supplements. […] Some people may find that honey can help alleviate a cough. […] In a 2021 review of studies, researchers looked at the effect of using honey to treat coughs in upper respiratory infections. The researchers found that honey was superior to usual care, both in suppressing the cough and in helping prevent the need for antibiotics.

• #87 Cough Relief: How to Get Rid of a Bad Cough

  https://www.webmd.com/cold-and-flu/cough-get-rid-home-hacks

  Coughing is a normal and healthy reflex. It helps your body clear your airways of mucus, smoke, and other irritants, but constant coughing can take a toll. […] Its best to stop a cough by treating the underlying cause, whether its a cold, allergies, acid reflux, blood pressure drugs, or other medications. But you also can try some home remedies to quiet and soothe your cough. […] Try honey and other natural cough remedies. Honey soothes the scratchiness in the back of your throat. One study found that honey works just as well as over-the-counter drugs for easing nighttime coughs. […] Use over-the-counter products for cough relief. Some natural OTC products that contain very low doses of aspirin also help reduce the symptoms of sore throat and cough. […] Here are some treatments that can help relieve coughing due to bronchitis: Cough suppressants. These medicines, often available over the counter, can help reduce the urge to cough.

• #88 Home remedies for cough

  https://www.medicalnewstoday.com/articles/322394

  A number of home remedies, such as honey and saltwater, may help manage cough symptoms. If home remedies do not help, over-the-counter and prescription medications are available. […] This article reviews natural remedies that may help treat a cough. […] People who want to try natural remedies to treat their cough should consider researching sources and brands. Additionally, some herbs and supplements can interfere with medications, which may result in unwanted side effects. It is best to consult a doctor before taking supplements. […] Some people may find that honey can help alleviate a cough. […] In a 2021 review of studies, researchers looked at the effect of using honey to treat coughs in upper respiratory infections. The researchers found that honey was superior to usual care, both in suppressing the cough and in helping prevent the need for antibiotics.

• #89 Home remedies for cough

  https://www.medicalnewstoday.com/articles/322394

  A person can use this remedy by swallowing a spoonful of honey or adding it to a hot drink, such as an herbal tea. […] Drinking various warm drinks may provide symptom relief from coughs. […] A wet cough, which produces mucus or phlegm, may improve with steam. […] A person should take a hot shower or bath and allow the bathroom to fill with steam. […] Marshmallow root is an herb with a long history of use as a treatment for coughs and sore throats. […] The authors of a 2020 review concluded that marshmallow root extract alone, and as part of various herbal remedies, may have a positive effect on cough symptom management. […] People have long used saltwater gargles to help alleviate sore throats and symptoms associated with the common cold. […] Bromelain is an enzyme that comes from pineapples. It has anti-inflammatory properties and may also have mucolytic properties, which means it can break down mucus and remove it from the body.

• #90 Cough

  https://www.nhs.uk/conditions/cough/

  A cough will usually clear up on its own within 3 to 4 weeks. […] You could also try: paracetamol or ibuprofen to treat any pain, hot lemon and honey (not suitable for babies under 1 year old), a herbal medicine called pelargonium (suitable for people aged 12 or over). […] But there’s limited evidence to show these work. Hot lemon with honey has a similar effect to cough medicines. […] If you have a cough, you can ask a pharmacist about: cough syrup, cough medicine (some cough medicines should not be given to children under 12 years old), cough sweets. These will not stop your cough, but may help you cough less. […] Decongestants and cough medicines containing codeine will not stop your cough. […] You can call 111 or get help from 111 online. […] Antibiotics are not normally prescribed for coughs. A GP will only prescribe them if you need them for example, if you have a bacterial infection or you’re at risk of complications.

• #91 Home remedies for cough

  https://www.medicalnewstoday.com/articles/322394

  A person can use this remedy by swallowing a spoonful of honey or adding it to a hot drink, such as an herbal tea. […] Drinking various warm drinks may provide symptom relief from coughs. […] A wet cough, which produces mucus or phlegm, may improve with steam. […] A person should take a hot shower or bath and allow the bathroom to fill with steam. […] Marshmallow root is an herb with a long history of use as a treatment for coughs and sore throats. […] The authors of a 2020 review concluded that marshmallow root extract alone, and as part of various herbal remedies, may have a positive effect on cough symptom management. […] People have long used saltwater gargles to help alleviate sore throats and symptoms associated with the common cold. […] Bromelain is an enzyme that comes from pineapples. It has anti-inflammatory properties and may also have mucolytic properties, which means it can break down mucus and remove it from the body.

• #92 Home remedies for cough

  https://www.medicalnewstoday.com/articles/322394

  A person can use this remedy by swallowing a spoonful of honey or adding it to a hot drink, such as an herbal tea. […] Drinking various warm drinks may provide symptom relief from coughs. […] A wet cough, which produces mucus or phlegm, may improve with steam. […] A person should take a hot shower or bath and allow the bathroom to fill with steam. […] Marshmallow root is an herb with a long history of use as a treatment for coughs and sore throats. […] The authors of a 2020 review concluded that marshmallow root extract alone, and as part of various herbal remedies, may have a positive effect on cough symptom management. […] People have long used saltwater gargles to help alleviate sore throats and symptoms associated with the common cold. […] Bromelain is an enzyme that comes from pineapples. It has anti-inflammatory properties and may also have mucolytic properties, which means it can break down mucus and remove it from the body.

• #93 Home remedies for cough

  https://www.medicalnewstoday.com/articles/322394

  A person can use this remedy by swallowing a spoonful of honey or adding it to a hot drink, such as an herbal tea. […] Drinking various warm drinks may provide symptom relief from coughs. […] A wet cough, which produces mucus or phlegm, may improve with steam. […] A person should take a hot shower or bath and allow the bathroom to fill with steam. […] Marshmallow root is an herb with a long history of use as a treatment for coughs and sore throats. […] The authors of a 2020 review concluded that marshmallow root extract alone, and as part of various herbal remedies, may have a positive effect on cough symptom management. […] People have long used saltwater gargles to help alleviate sore throats and symptoms associated with the common cold. […] Bromelain is an enzyme that comes from pineapples. It has anti-inflammatory properties and may also have mucolytic properties, which means it can break down mucus and remove it from the body.

• #94 Home remedies for cough

  https://www.medicalnewstoday.com/articles/322394

  Thyme has both culinary and medicinal uses and is a commonly used remedy for a cough, sore throat, bronchitis, and digestive issues. […] In a 2015 meta-analysis of several studies, researchers noted that strong evidence suggests that using thyme preparations helped alleviate peoples cough symptoms. […] NAC is a supplement made from the amino acid L-cysteine. Reducing mucus in the airways may lessen the frequency and severity of a wet cough. […] People may use NAC in the treatment of chronic respiratory conditions such as chronic bronchitis, a prolonged inflammation of the airways that causes mucus buildup and a cough. […] A person may also find some relief with over-the-counter medications, such as those containing dextromethorphan, or cough drops. These can help suppress a cough. […] There is no cure for a cough. However, natural remedies such as honey, ginger, and hot fluids may help treat it.

• #95 Home remedies for cough

  https://www.medicalnewstoday.com/articles/322394

  A number of home remedies, such as honey and saltwater, may help manage cough symptoms. If home remedies do not help, over-the-counter and prescription medications are available. […] This article reviews natural remedies that may help treat a cough. […] People who want to try natural remedies to treat their cough should consider researching sources and brands. Additionally, some herbs and supplements can interfere with medications, which may result in unwanted side effects. It is best to consult a doctor before taking supplements. […] Some people may find that honey can help alleviate a cough. […] In a 2021 review of studies, researchers looked at the effect of using honey to treat coughs in upper respiratory infections. The researchers found that honey was superior to usual care, both in suppressing the cough and in helping prevent the need for antibiotics.

• #96 Chronic Cough: Evaluation and Management | AAFP

  https://www.aafp.org/pubs/afp/issues/2017/1101/p575.html

  Neuromodulators have shown some benefit in randomized trials based on the hypothesis that refractory chronic cough may be due to hypersensitivity of the cough reflex caused by peripheral (afferent limb of the cough reflex) and central mechanisms (central sensitization). […] Gabapentin (Neurontin, 1,800 mg per day), which improved symptoms within four weeks; pregabalin (Lyrica, 300 mg per day) in conjunction with speech therapy, which showed greater improvement vs. placebo with speech therapy; and speech and language therapy alone. […] Chronic cough in children younger than 15 years is defined as cough lasting more than four weeks. […] The most common causes of chronic cough in children six to 14 years of age are asthma, protracted bacterial bronchitis, and UACS. […] Treatment consists of a two-week course of an appropriate antibiotic, such as amoxicillin/clavulanate (Augmentin).

• #97 Chronic Cough: Evaluation and Management | AAFP

  https://www.aafp.org/pubs/afp/issues/2017/1101/p575.html

  Neuromodulators have shown some benefit in randomized trials based on the hypothesis that refractory chronic cough may be due to hypersensitivity of the cough reflex caused by peripheral (afferent limb of the cough reflex) and central mechanisms (central sensitization). […] Gabapentin (Neurontin, 1,800 mg per day), which improved symptoms within four weeks; pregabalin (Lyrica, 300 mg per day) in conjunction with speech therapy, which showed greater improvement vs. placebo with speech therapy; and speech and language therapy alone. […] Chronic cough in children younger than 15 years is defined as cough lasting more than four weeks. […] The most common causes of chronic cough in children six to 14 years of age are asthma, protracted bacterial bronchitis, and UACS. […] Treatment consists of a two-week course of an appropriate antibiotic, such as amoxicillin/clavulanate (Augmentin).

• #98 Chronic Cough: Evaluation and Management | AAFP

  https://www.aafp.org/pubs/afp/issues/2017/1101/p575.html

  Neuromodulators have shown some benefit in randomized trials based on the hypothesis that refractory chronic cough may be due to hypersensitivity of the cough reflex caused by peripheral (afferent limb of the cough reflex) and central mechanisms (central sensitization). […] Gabapentin (Neurontin, 1,800 mg per day), which improved symptoms within four weeks; pregabalin (Lyrica, 300 mg per day) in conjunction with speech therapy, which showed greater improvement vs. placebo with speech therapy; and speech and language therapy alone. […] Chronic cough in children younger than 15 years is defined as cough lasting more than four weeks. […] The most common causes of chronic cough in children six to 14 years of age are asthma, protracted bacterial bronchitis, and UACS. […] Treatment consists of a two-week course of an appropriate antibiotic, such as amoxicillin/clavulanate (Augmentin).

• #99 Medications for Chronic Cough | NYU Langone Health

  https://nyulangone.org/conditions/chronic-cough-in-children/treatments/medications-for-chronic-cough

  At Hassenfeld Childrens Hospital at NYU Langone, treatment of children with a chronic cough depends on the underlying cause. After our doctors have identified the source of your childs symptoms, they can select the most effective medical therapy. Most children with a chronic cough feel better within a few weeks of starting treatment, especially if the cause is a bacterial infection. […] If your child has a bacterial infection, our doctors may prescribe broad-spectrum antibiotics for two weeks or longer. These medications are effective against many types of bacteria, eliminating them from the airways. […] For children with cough-variant asthma, a breathing disorder in which coughing is the only symptom, our doctors may prescribe anti-inflammatory medicines to reduce inflammation in the airways. Your childs symptoms may gradually improve within six to eight weeks after beginning asthma treatment.

• #100 Medications for Chronic Cough | NYU Langone Health

  https://nyulangone.org/conditions/chronic-cough-in-children/treatments/medications-for-chronic-cough

  Our doctors may recommend over-the-counter antihistamines and nasal steroids to relieve allergy symptoms, which can contribute to an ongoing cough in children. […] Our doctors do not recommend over-the-counter and prescription cough suppressants, such as those that contain dextromethorphan and codeine. These medications do not address the underlying cause and can lead to significant side effects in young children. […] When a chronic cough is not caused by a bacterial infection, allergies, or asthma, a child may need other types of treatment to address the underlying cause. Our doctors make referrals to other specialists at Hassenfeld Childrens Hospital who can treat less common causes of chronic cough, such as gastroesophageal reflux disease, congenital lung abnormalities, and cystic fibrosis, if needed.

• #101 Medications for Chronic Cough | NYU Langone Health

  https://nyulangone.org/conditions/chronic-cough-in-children/treatments/medications-for-chronic-cough

  Our doctors may recommend over-the-counter antihistamines and nasal steroids to relieve allergy symptoms, which can contribute to an ongoing cough in children. […] Our doctors do not recommend over-the-counter and prescription cough suppressants, such as those that contain dextromethorphan and codeine. These medications do not address the underlying cause and can lead to significant side effects in young children. […] When a chronic cough is not caused by a bacterial infection, allergies, or asthma, a child may need other types of treatment to address the underlying cause. Our doctors make referrals to other specialists at Hassenfeld Childrens Hospital who can treat less common causes of chronic cough, such as gastroesophageal reflux disease, congenital lung abnormalities, and cystic fibrosis, if needed.

• #102 Chronic Cough Treatment | The University of Kansas Health System

  https://www.kansashealthsystem.com/care/conditions/chronic-cough

  A chronic cough isnt related to specific illness or health concern. […] With the help of our skilled team at The University of Kansas Health System, we can identify the underlying cause of your chronic cough and help you get your life back on track. […] Refractory chronic cough isnt caused by another health condition. Symptoms persist even after having tried multiple treatments. […] Symptomatic chronic cough is when the coughing symptoms are caused by an underlying condition, and the symptoms resolve when that condition is properly treated. […] The treatment to help get rid of your chronic cough will depend on the cause for your coughing. […] Your doctor may recommend different treatments and medications to eliminate your chronic cough: Acid reflux medications, Antibiotics, Antihistamines, Asthma medications, Decongestants, Increased fluid intake (to thin mucus).

• #103 Chronic Cough: Evaluation and Management | AAFP

  https://www.aafp.org/pubs/afp/issues/2017/1101/p575.html

  In patients with refractory chronic cough, referral to a pulmonologist or otolaryngologist should be considered, as well as a trial of gabapentin (Neurontin), pregabalin (Lyrica), or speech therapy. […] The diagnostic approach should focus on detection and treatment of the four most common causes of chronic cough in adults: upper airway cough syndrome (UACS), asthma, nonasthmatic eosinophilic bronchitis, and gastroesophageal reflux disease (GERD)/laryngopharyngeal reflux disease. […] If a specific cause is identified, therapy should be started; otherwise, initial treatment includes a decongestant combined with a first-generation antihistamine. […] Treatment usually includes an inhaled bronchodilator and high-dose inhaled corticosteroid. A leukotriene receptor antagonist (e.g., montelukast [Singulair]) can also be useful.

• #104 Chronic Cough: Evaluation and Management | AAFP

  https://www.aafp.org/pubs/afp/issues/2017/1101/p575.html

  In patients with refractory chronic cough, referral to a pulmonologist or otolaryngologist should be considered, as well as a trial of gabapentin (Neurontin), pregabalin (Lyrica), or speech therapy. […] The diagnostic approach should focus on detection and treatment of the four most common causes of chronic cough in adults: upper airway cough syndrome (UACS), asthma, nonasthmatic eosinophilic bronchitis, and gastroesophageal reflux disease (GERD)/laryngopharyngeal reflux disease. […] If a specific cause is identified, therapy should be started; otherwise, initial treatment includes a decongestant combined with a first-generation antihistamine. […] Treatment usually includes an inhaled bronchodilator and high-dose inhaled corticosteroid. A leukotriene receptor antagonist (e.g., montelukast [Singulair]) can also be useful.

• #105 Management of chronic refractory cough in adults

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7501523/

  Speech pathology can be combined with a neuromodulator to give an enhanced treatment response of longer duration suggesting that non-pharmacologic treatment may play a key role in the management of CRC. […] The two most influential guidelines for the management of cough, and particularly CRC, are: 1) those developed and updated by the ACCP, and 2) those developed by the ERS. […] According to current ERS guidelines, multi-component physiotherapy/speech and language therapy interventions should be considered for CRC patients who wish an alternative to drug treatment. […] Despite the efficacy and advantages of speech pathology intervention, there is limited guidance in the literature as to when patients should be referred for treatment. […] Pathological mechanisms may affect central and peripheral neuromodulators or cause a hypersensitivity of the cough reflex.

• #106 Diagnosing and treating chronic cough in adults – European Lung Foundation

  https://europeanlung.org/en/information-hub/guidelines/diagnosing-and-treating-chronic-cough-in-adults/

  There is currently a lot of research taking place that is looking into how to understand and treat chronic cough. We have a lot to learn, but we are making good progress. Due to new research, your doctor may recommend something that has not been covered in this booklet. There may be the opportunity to volunteer to take part in one of several clinical trials that are testing new drugs for chronic cough. If you are interested in this, your doctor will be able to advise you of the details.

• #107 Management of chronic refractory cough in adults

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7501523/

  Speech pathology can be combined with a neuromodulator to give an enhanced treatment response of longer duration suggesting that non-pharmacologic treatment may play a key role in the management of CRC. […] The two most influential guidelines for the management of cough, and particularly CRC, are: 1) those developed and updated by the ACCP, and 2) those developed by the ERS. […] According to current ERS guidelines, multi-component physiotherapy/speech and language therapy interventions should be considered for CRC patients who wish an alternative to drug treatment. […] Despite the efficacy and advantages of speech pathology intervention, there is limited guidance in the literature as to when patients should be referred for treatment. […] Pathological mechanisms may affect central and peripheral neuromodulators or cause a hypersensitivity of the cough reflex.

• #108 Chronic Cough | Condition | UT Southwestern Medical Center

  https://utswmed.org/conditions-treatments/chronic-cough/

  UT Southwestern Medical Center provides expert care for people who have a chronic cough and other conditions affecting the airways, larynx (voice box), throat, and lungs. Using the latest technology, we work to evaluate, diagnose, and treat the underlying causes of chronic cough. […] Our multidisciplinary approach often combines the expertise of fellowship-trained laryngologists, pulmonologists, speech-language pathologists, allergists, and other care professionals focused on voice, throat, and lung conditions. Our physicians, therapists, and researchers are widely recognized as experts in the accurate diagnosis and effective treatment of chronic cough. […] Treatment for chronic cough involves remedying the underlying cause, and options include: […] Cough suppressant medications to control the cough […] Cough suppression techniques, taught by our speech-language pathologists, to help reduce the severity and frequency of the cough.

• #109 Chronic Cough | Atrium Health Wake Forest Baptist

  https://www.wakehealth.edu/condition/c/chronic-cough

  Chronic cough, however, is defined as a cough that persists longer than 8 weeks in an adult or 4 weeks in a child. […] Diagnosis of chronic cough may require evaluation with several specialized medical providers. Chronic cough is not a disease; its a symptom. In order to stop the cough, we have to determine the cause. […] Treatments for chronic cough vary based on multiple potential etiologies of cough and are unique to each patient. Treatments range from laryngeal control therapy targeting behavioral modifications to address cough, trials of corticosteroids, decongestants, acid blockers, antihistamines, and medications or injections for neuropathic disorders that can help reduce the frequency and severity of cough. […] Treating a chronic cough may involve specialists from one or more of many areas of medicine including allergy and immunology, ENT, pulmonology, gastroenterology, cardiology and speech-language pathology. Through multidisciplinary evaluation and treatment, patients are often able to find effective therapies for virtually all of the underlying causes of a chronic cough.

• #110 Chronic Cough | Atrium Health Wake Forest Baptist

  https://www.wakehealth.edu/condition/c/chronic-cough

  Chronic cough, however, is defined as a cough that persists longer than 8 weeks in an adult or 4 weeks in a child. […] Diagnosis of chronic cough may require evaluation with several specialized medical providers. Chronic cough is not a disease; its a symptom. In order to stop the cough, we have to determine the cause. […] Treatments for chronic cough vary based on multiple potential etiologies of cough and are unique to each patient. Treatments range from laryngeal control therapy targeting behavioral modifications to address cough, trials of corticosteroids, decongestants, acid blockers, antihistamines, and medications or injections for neuropathic disorders that can help reduce the frequency and severity of cough. […] Treating a chronic cough may involve specialists from one or more of many areas of medicine including allergy and immunology, ENT, pulmonology, gastroenterology, cardiology and speech-language pathology. Through multidisciplinary evaluation and treatment, patients are often able to find effective therapies for virtually all of the underlying causes of a chronic cough.

• #111 Chronic Cough: Causes & Treatment

  https://my.clevelandclinic.org/health/symptoms/15048-chronic-cough-overview

  Chronic cough is a cough that lasts more than eight weeks in adults and four weeks in children. Treatment for chronic cough depends on the associated health condition. Your healthcare provider will discuss a tailored treatment plan based on your unique needs. […] Possible chronic cough treatments may include: Decongestants to relieve postnasal drip. Nasal sprays to alleviate sneezing, runny nose and other allergy symptoms. Steroids or inhaled bronchodilators to reduce asthma-induced airway inflammation. Antibiotics for infections like bacterial pneumonia, sinusitis or bronchitis. Changing certain medications or dosages. Avoiding certain foods to reduce your risk of GERD. […] If coughing is having a negative impact on your life, contact a healthcare provider to find the cause. Finding the cause will help your healthcare provider determine a treatment, so you can go back to sleeping, eating, moving and feeling well.

• #112 Chronic Cough: Causes & Treatment

  https://my.clevelandclinic.org/health/symptoms/15048-chronic-cough-overview

  Chronic cough is a cough that lasts more than eight weeks in adults and four weeks in children. Treatment for chronic cough depends on the associated health condition. Your healthcare provider will discuss a tailored treatment plan based on your unique needs. […] Possible chronic cough treatments may include: Decongestants to relieve postnasal drip. Nasal sprays to alleviate sneezing, runny nose and other allergy symptoms. Steroids or inhaled bronchodilators to reduce asthma-induced airway inflammation. Antibiotics for infections like bacterial pneumonia, sinusitis or bronchitis. Changing certain medications or dosages. Avoiding certain foods to reduce your risk of GERD. […] If coughing is having a negative impact on your life, contact a healthcare provider to find the cause. Finding the cause will help your healthcare provider determine a treatment, so you can go back to sleeping, eating, moving and feeling well.

• #113 Chronic Cough | Diagnosis & Treatment | IU Health

  https://iuhealth.org/find-medical-services/chronic-cough

  We help treat your cough that has lasted more than eight weeks […] Chronic cough refers to a cough that lasts more than eight weeks. Many different lung diseases cause chronic coughing. […] IU Health Pulmonology & Respiratory Care physicians create personalized treatment plans that may include the following services depending on the cause of your cough: Education. Learning more about your condition allows you to make lifestyle changes that reduce the severity of your cough. […] Prescription medications. Depending on the cause of your cough, prescription medications may manage your symptoms and help you breathe easier. […] Pulmonary rehabilitation. During pulmonary rehabilitation, you perform breathing and physical exercises that can greatly improve lung function. […] Lung volume reduction surgery. If parts of your lungs become severely damaged, removing them through lung volume reduction surgery can help the healthy tissue in your lungs perform better. […] Lung transplant is a treatment option for lung disease that can no longer be controlled with other methods. […] We help you learn to breathe easier through exercise and education so you can build your strength and energy back and learn to manage your lung condition.

• #114 Updates in Treatment of Adults With Chronic Cough

  https://www.ajmc.com/view/updates-in-treatment-of-adults-with-chronic-cough

  Historical treatments, such as opiates and neuromodulators, have been used with limited success. […] Emerging agents that target specific channel receptors have shown initial positive benefits concerning cough frequency, severity, and quality of life and may become available on the market as they have shown to be generally well tolerated without any safety concerns in clinical studies. […] Chronic cough management is often complex, requiring an individualized treatment plan. […] Therefore, treatment options discussed below include a summary of efficacy and tolerability data to guide clinical decision making. […] Current CHEST guidelines recommend a trial of multimodality speech pathology therapy in patients with UCC. […] This recommendation was based on positive cough severity, randomized control trial data.

• #115 Diagnosing and treating chronic cough in adults – European Lung Foundation

  https://europeanlung.org/en/information-hub/guidelines/diagnosing-and-treating-chronic-cough-in-adults/

  Coughing is a normal and important reflex which prevents you from choking and allows you to clear your lungs or throat. Coughing can become a problem when it is persistent even when you are not ill or have not been exposed to an obvious irritant such as cigarette smoke. This is called chronic cough. Chronic cough affects between five and ten people in every 100. […] Chronic cough is a very difficult condition to treat. Even after thorough testing it may not be possible to identify how to treat your cough. Your doctor may recommend taking a treatment for a period of time to see if it works. Different treatments take different amounts of time to work, and some might take months to see an effect. […] Cough control therapy is a form of speech and language therapy/ physiotherapy. It teaches ways to suppress the urge to cough an how to avoid certain cough triggers. It can be effective at reducing the frequency of coughing and there are no known side effects of this therapy. It is important to find someone who has had previous experience in treating patients with chronic cough.

• #116 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Finding out what’s causing a chronic cough is very important to effective treatment. In many cases, more than one underlying condition may be causing your chronic cough. […] If you smoke, your healthcare professional likely will talk with you about your readiness to quit and give you advice on how to achieve this goal. If you’re taking an ACE inhibitor medicine, your health professional may switch you to another medicine that doesn’t have cough as a side effect. […] Medicines used to treat chronic cough may include: […] Antihistamines, corticosteroids and decongestants. These medicines are standard treatment for allergies and postnasal drip. […] Inhaled asthma medicines. The most effective treatments for asthma-related cough are corticosteroids and bronchodilators. They reduce inflammation and open up your airways.

• #117 Patient education: Chronic cough in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-cough-in-adults-beyond-the-basics

  Chronic cough treatment aims to eliminate the underlying cause. […] Treatment of chronic cough aims to eliminate the underlying cause. Most of the time, each type of treatment is tried separately, one after another, instead of all at the same time. […] Here are some examples of treatment choices for different causes of cough. […] A cough related to postnasal drip may improve with the use of a decongestant, nasal or oral antihistamine, nasal glucocorticoid, or a nasal spray that contains ipratropium. […] If your cough is due to asthma, you will be given the standard treatment for asthma, which includes an inhaled glucocorticoid such as fluticasone (Flovent), budesonide (Pulmicort), or beclomethasone (QVAR). […] Cough due to acid reflux may respond to the following lifestyle changes: Avoid substances that increase reflux, such as high-fat foods, chocolate, colas, red wine, acidic juices, and excessive alcohol.

• #118 Chronic Cough: Practice Essentials, Mechanism of Cough, Causes of Chronic Cough

  https://emedicine.medscape.com/article/1048560-overview

  The management of chronic cough presents a challenge for the clinician. Typically defined as a cough that persists for longer than 8 weeks, this is the most common presenting symptom in adults who seek medical treatment in an ambulatory setting. Chronic cough is estimated to occur in up to 40% of the population. […] A multidisciplinary approach is often needed, with the primary care provider coordinating care with appropriate referrals to the otolaryngologist, pulmonologist, or both, as appropriate. […] Management should begin with cessation of smoking or angiotensin-converting enzyme (ACE) inhibitor use in those patients whose history indicates such action. Most patients have a resolution of their cough within 4 weeks of smoking cessation. Cough related to ACE inhibitor use usually subsides within 2 weeks, but the median time has been reported to be 26 days.

• #119 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Finding out what’s causing a chronic cough is very important to effective treatment. In many cases, more than one underlying condition may be causing your chronic cough. […] If you smoke, your healthcare professional likely will talk with you about your readiness to quit and give you advice on how to achieve this goal. If you’re taking an ACE inhibitor medicine, your health professional may switch you to another medicine that doesn’t have cough as a side effect. […] Medicines used to treat chronic cough may include: […] Antihistamines, corticosteroids and decongestants. These medicines are standard treatment for allergies and postnasal drip. […] Inhaled asthma medicines. The most effective treatments for asthma-related cough are corticosteroids and bronchodilators. They reduce inflammation and open up your airways.

• #120 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Finding out what’s causing a chronic cough is very important to effective treatment. In many cases, more than one underlying condition may be causing your chronic cough. […] If you smoke, your healthcare professional likely will talk with you about your readiness to quit and give you advice on how to achieve this goal. If you’re taking an ACE inhibitor medicine, your health professional may switch you to another medicine that doesn’t have cough as a side effect. […] Medicines used to treat chronic cough may include: […] Antihistamines, corticosteroids and decongestants. These medicines are standard treatment for allergies and postnasal drip. […] Inhaled asthma medicines. The most effective treatments for asthma-related cough are corticosteroids and bronchodilators. They reduce inflammation and open up your airways.

• #121 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Antibiotics. If a bacterial, fungal or mycobacterial infection is causing your chronic cough, your healthcare professional may prescribe antibiotic medicines for the infection. […] Acid blockers. When lifestyle changes don’t take care of acid reflux, you may be treated with medicines that block acid production. Some people need surgery to resolve the problem. […] Your healthcare professional works to find the cause of your cough and the best treatment for you. During that time, your healthcare professional also may prescribe a medicine to reduce coughing, called a cough suppressant. Cough suppressants are not recommended for children. […] Cough and cold medicines available without a prescription treat the symptoms of coughs and colds not the underlying disease. Research suggests that these medicines don’t work any better than no medicine at all. These medicines are not recommended for children because of potentially serious side effects, including fatal overdoses in children younger than 2 years old. […] Don’t use over-the-counter cough and cold medicines, except for fever reducers and pain relievers, to treat coughs and colds in children younger than 6 years old. Also, avoid use of these medicines for children younger than 12 years old. Check with your healthcare professional for guidance.

• #122 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Antibiotics. If a bacterial, fungal or mycobacterial infection is causing your chronic cough, your healthcare professional may prescribe antibiotic medicines for the infection. […] Acid blockers. When lifestyle changes don’t take care of acid reflux, you may be treated with medicines that block acid production. Some people need surgery to resolve the problem. […] Your healthcare professional works to find the cause of your cough and the best treatment for you. During that time, your healthcare professional also may prescribe a medicine to reduce coughing, called a cough suppressant. Cough suppressants are not recommended for children. […] Cough and cold medicines available without a prescription treat the symptoms of coughs and colds not the underlying disease. Research suggests that these medicines don’t work any better than no medicine at all. These medicines are not recommended for children because of potentially serious side effects, including fatal overdoses in children younger than 2 years old. […] Don’t use over-the-counter cough and cold medicines, except for fever reducers and pain relievers, to treat coughs and colds in children younger than 6 years old. Also, avoid use of these medicines for children younger than 12 years old. Check with your healthcare professional for guidance.

• #123 Treatment of Unexplained Chronic Cough

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5831652/

  Unexplained chronic cough (UCC) causes significant impairments in quality of life. Effective assessment and treatment approaches are needed for UCC. […] The evidence supporting the diagnosis and management of UCC is limited. UCC requires further study to establish agreed terminology and the optimal methods of investigation using established criteria for intervention fidelity. Speech pathology-based cough suppression is suggested as a treatment option for UCC. […] In adult patients with unexplained chronic cough, we suggest a therapeutic trial of multimodality speech pathology therapy. […] In adult patients with unexplained chronic cough, we suggest a therapeutic trial of gabapentin as long as the potential side effects and the risk-benefit profile are discussed with patients before use of the medication, and there is a reassessment of the risk-benefit profile at 6 months before continuing the drug.

• #124 Management of chronic refractory cough in adults

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7501523/

  Cough is a common respiratory symptom that is considered to be chronic when it lasts more than eight weeks. […] Current international guidelines provide algorithms for the management of chronic cough: in most cases, treatment of the underlying disease is sufficient to improve or resolve cough symptoms. […] If chronic cough persists even after treatment of the underlying disease, or if the chronic cough is not attributable to any cause, then a symptomatic approach with neuromodulators may be considered, with gabapentin as the first choice, and opioids or macrolides as alternatives. […] Speech pathology treatment and/or neuromodulators should be discussed with patients and alternative options carefully considered, taking into account risk/benefit. […] Novel promising drugs are under investigation (e.g. P23 inhibitors), but additional studies are needed in this field.

• #125 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Antibiotics. If a bacterial, fungal or mycobacterial infection is causing your chronic cough, your healthcare professional may prescribe antibiotic medicines for the infection. […] Acid blockers. When lifestyle changes don’t take care of acid reflux, you may be treated with medicines that block acid production. Some people need surgery to resolve the problem. […] Your healthcare professional works to find the cause of your cough and the best treatment for you. During that time, your healthcare professional also may prescribe a medicine to reduce coughing, called a cough suppressant. Cough suppressants are not recommended for children. […] Cough and cold medicines available without a prescription treat the symptoms of coughs and colds not the underlying disease. Research suggests that these medicines don’t work any better than no medicine at all. These medicines are not recommended for children because of potentially serious side effects, including fatal overdoses in children younger than 2 years old. […] Don’t use over-the-counter cough and cold medicines, except for fever reducers and pain relievers, to treat coughs and colds in children younger than 6 years old. Also, avoid use of these medicines for children younger than 12 years old. Check with your healthcare professional for guidance.

• #126 Treating and Managing Chronic Cough | American Lung Association

  https://www.lung.org/lung-health-diseases/lung-disease-lookup/chronic-cough/treating-and-managing

  A diagnosis of chronic cough can be both confirming and frustrating. […] If your cough is identified as being caused by a specific medical condition such as asthma, COPD, pulmonary fibrosis, sinus drainage issues, nasal polyps, gastroesophageal reflux (GERD) there may be specific treatments prescribed by your healthcare provider that can be helpful in getting rid of the cough or at least making it more manageable. […] Lifestyle changes are not a cure for your chronic cough but may help in managing your cough. […] While a chronic cough can feel isolating, you are not alone. […] You may qualify to participate in a clinical trial, a regulated research study in which people volunteer to test new treatments or therapies. […] Better Breathers Clubs teach you ways to cope with lung disease and provide support from others who share in your struggles.

• #127 Chronic cough – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-cough/diagnosis-treatment/drc-20351580

  Antibiotics. If a bacterial, fungal or mycobacterial infection is causing your chronic cough, your healthcare professional may prescribe antibiotic medicines for the infection. […] Acid blockers. When lifestyle changes don’t take care of acid reflux, you may be treated with medicines that block acid production. Some people need surgery to resolve the problem. […] Your healthcare professional works to find the cause of your cough and the best treatment for you. During that time, your healthcare professional also may prescribe a medicine to reduce coughing, called a cough suppressant. Cough suppressants are not recommended for children. […] Cough and cold medicines available without a prescription treat the symptoms of coughs and colds not the underlying disease. Research suggests that these medicines don’t work any better than no medicine at all. These medicines are not recommended for children because of potentially serious side effects, including fatal overdoses in children younger than 2 years old. […] Don’t use over-the-counter cough and cold medicines, except for fever reducers and pain relievers, to treat coughs and colds in children younger than 6 years old. Also, avoid use of these medicines for children younger than 12 years old. Check with your healthcare professional for guidance.

• #128 ‘My cough interferes with everything’: New research could help refractory chronic cough patients after decades of depression, pain, and sleep loss | GSK

  https://www.gsk.com/en-gb/behind-the-science-magazine/refractory-chronic-cough-patients-symptoms/

  Around 10 million people globally suffer from a severe cough that persists for more than a year, leading to loss of sleep, depression, pain, and social isolation. […] After ruling out possible underlying causes, specialists such as Dr Dicpinigaitis and his team often reach the diagnosis of refractory chronic cough. […] To make matters worse, there are limited treatment options available in most of the world, and while drugs known as neuromodulators may help, only a fraction of patients respond well to and can tolerate them. […] We believe there is a significant dysfunction of the cough reflex such that it becomes overstimulated and keeps firing off cough signals to the body inappropriately, Lipson says. […] Now, however, scientists are advancing in their effort to inhibit the stimulation of airway receptors that contribute to excessive coughing. […] The extent to which this new approach reduces the frequency and severity of refractory chronic cough remains to be seen, but the progress in research is offering some hope to long suffering patients across the world, as well as physicians like Dr Dicpinigaitis.

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