Materiały źródłowe

• #1 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  Gastrointestinal stromal tumours (GIST) constitute a separate group of mesenchymal neoplasms of the gastrointestinal tract. […] Nursing practice with reference to GIST danger is connected with biopsychosocial interventions of perioperative, oncological and palliative procedures and involves the area of health education mainly oriented towards shaping preventive procedures which favour early disease detection and support therapy and recovery. […] During this period of disease, nursing care will be focused on, among others, patient preparation for diagnostic procedures CT, biopsy examinations or endoscopic ultrasonography. […] An important task in postoperative nursing care is prevention of postoperative complications including those resulting from the patient’s immobilization (pneumonia, thrombophlebitis).

• #2 GIST (Gastrointestinal Stromal Tumor) | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/soft-tissue-sarcoma/types/gist-gastrointestinal-stromal-tumor

  A gastrointestinal stromal tumor (GIST) is a rare cancer. It is a type of soft tissue sarcoma that often begins in the abdomen. […] It is very important to receive a diagnosis from a team of doctors that is highly experienced in the diagnosis and treatment of soft tissue sarcoma. Getting the correct evaluation and diagnosis is the first step to being cured. […] The primary treatment for a GIST is surgery to remove the tumor. The surgery thats right for you depends on the exact size and location of the tumor. […] Surgery for a GIST is often followed by a three-year course of the drug imatinib (Gleevec). Some people dont need any treatment other than surgery. Radiation is rarely recommended for a GIST. […] For GISTs that come back after initial treatment, the soft tissue sarcoma experts at MSK may be able to offer surgery, cryoablation, radiofrequency ablation, or imatinib or other drug therapies, such as sunitinib (Sutent).

• #3 Gastrointestinal Stromal Tumors | Treatment Update GIST | CancerCare

  https://www.cancercare.org/publications/136-treatment_update_gastrointestinal_stromal_tumors

  GIST (gastrointestinal stromal tumors) is a rare form of cancer, with approximately 5,000 cases diagnosed in the United States each year. […] The best treatment approach is often guided by an interdisciplinary team composed of medical oncologists, radiologists, surgeons and nurses. […] Surgery is the primary approach in the treatment of localized (non-metastatic) GIST. […] The need for adjuvant (post-surgery) treatment is determined based on the risk of the GIST recurring. […] Targeted therapies focus on specific molecules and cell mechanisms thought to be important for cancer cell survival and growth, taking advantage of what researchers have learned in recent years about how tumors grow. […] GIST is treated with medications called tyrosine kinase inhibitors (TKIs) which specifically block, or inhibit, KIT, slowing GIST cell growth.

• #4 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  Gastrointestinal stromal tumours (GIST) constitute a separate group of mesenchymal neoplasms of the gastrointestinal tract. […] Nursing practice with reference to GIST danger is connected with biopsychosocial interventions of perioperative, oncological and palliative procedures and involves the area of health education mainly oriented towards shaping preventive procedures which favour early disease detection and support therapy and recovery. […] During this period of disease, nursing care will be focused on, among others, patient preparation for diagnostic procedures CT, biopsy examinations or endoscopic ultrasonography. […] An important task in postoperative nursing care is prevention of postoperative complications including those resulting from the patient’s immobilization (pneumonia, thrombophlebitis).

• #5 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  Gastrointestinal stromal tumours (GIST) constitute a separate group of mesenchymal neoplasms of the gastrointestinal tract. […] Nursing practice with reference to GIST danger is connected with biopsychosocial interventions of perioperative, oncological and palliative procedures and involves the area of health education mainly oriented towards shaping preventive procedures which favour early disease detection and support therapy and recovery. […] During this period of disease, nursing care will be focused on, among others, patient preparation for diagnostic procedures CT, biopsy examinations or endoscopic ultrasonography. […] An important task in postoperative nursing care is prevention of postoperative complications including those resulting from the patient’s immobilization (pneumonia, thrombophlebitis).

• #6 Daily Life With GIST

  https://www.webmd.com/cancer/daily-life-with-gist

  Finding out that you have gastrointestinal stromal tumor (GIST) can feel overwhelming, especially since it is such an uncommon type of cancer. […] Gastrointestinal stromal tumor is a type of cancer known as a soft tissue sarcoma that affects the GI tract. However, GIST has become a treatable disease over time. Maintaining a healthy lifestyle and following doctors orders will help improve your treatment experience. […] The symptoms of GIST can have a large impact on your life because they affect your GI tract. You may have severe pain in your abdomen. Eating may become difficult due to nausea, stomach pain, and a feeling of fullness. You may feel fatigue, which may affect your activities of daily living. […] GIST treatment may have side effects as well. Talk to your doctor if symptoms or treatment side effects persist or become severe or when symptoms interfere with your life. Talk to your health care provider about any treatment side effects so that your doctor can prescribe supportive medication to help relieve treatment-related symptoms.

• #7 Gastrointestinal Stromal Tumors Treatment – NCI

  https://www.cancer.gov/types/soft-tissue-sarcoma/patient/gist-treatment-pdq

  Gastrointestinal stromal tumor is a disease in which abnormal cells form in the tissues of the gastrointestinal tract. […] Genetic factors can increase the risk of having a gastrointestinal stromal tumor. […] Signs of gastrointestinal stromal tumors include blood in the stool or vomit. […] Tests that examine the GI tract are used to diagnose gastrointestinal stromal tumors. […] Very small GISTs are common. […] Certain factors affect prognosis (chance of recovery) and treatment options. […] If the GIST has not spread and is in a place where surgery can be safely done, the tumor and some of the tissue around it may be removed. […] Targeted therapy is a type of treatment that uses drugs or other substances to identify and attack specific cancer cells. […] Watchful waiting is closely monitoring a patient’s condition without giving any treatment until signs or symptoms appear or change.

• #8

  https://winshipcancer.emory.edu/cancer-types-and-treatments/gastrointestinal-stromal-tumor/prevention.php

  Winship Cancer Institute of Emory Universitys team of sarcoma and gastrointestinal cancer experts is dedicated to treating your gastrointestinal stromal tumors (GIST) with a personalized approach to give you the best outcomes possible. […] If you or a loved one is experiencing any of the above symptoms, call your doctor. Bleeding from the tumor is a very serious symptom and should be addressed immediately. […] When you come to Winship for cancer care, you have a team of experts dedicated to your well-being. Our gastrointestinal cancer experts are ready to see you. If youve been diagnosed with a gastrointestinal cancer, call us today at 404-778-0032 to schedule a visit.

• #9 Gastrointestinal Stromal Tumors (GISTs) Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/278845-treatment

  When feasible, surgical resection is the treatment of choice for gastrointestinal stromal tumors (GISTs) and offers the only chance for cure. Medical therapy is indicated in the following four scenarios: Preoperatively, to enable resectability or decrease morbidity by shrinking the tumor […] After surgery, to decrease recurrence […] In metastatic disease, as definitive treatment […] In recurrent, unresectable disease, as definitive treatment. […] Surgery is the definitive therapy for localized GISTs. Despite the proven success of imatinib and other newer tyrosine kinase inhibitors, surgical resection remains the treatment of choice and offers the only chance for cure of GIST. The main operative principle is resection of the tumor with negative microscopic margins. […] For small GISTs, local resection may be adequate, if it is technically possible and does not compromise a complete resection. Avoid enucleation of small tumors, since predicting the preoperative malignant potential of GISTs is difficult even if the tumor appears benign.

• #10 Gastrointestinal stromal tumor | World Journal of Surgical Oncology | Full Text

  https://wjso.biomedcentral.com/articles/10.1186/1477-7819-7-61

  Surgical resection of the local disease is the gold standard therapy. Its goal is complete resection of the disease with avoidance of tumor rupture. Tumor size determines the survival and not the negative microscopic surgical margins. Regional lymph node resection has no value since GIST rarely gives rise to lymph node metastases. However, the tumor size or its location may determine the exact extent of resection. En block resection of the local disease is recommended when GISTs adheres to contiguous organ. GISTs are soft and fragile, so a tumor rupture must be avoided because it is associated with an increased risk for development of peritoneal implants. Complete surgical resection is connected with 48-65% five year survival. Partial resection must only be performed in case of large tumors, for palliative purposes or the control of symptoms or complications, such as compression of other organs, hemorrhage or even pain. As it is already mentioned, surgery is the preferred management of GISTs, where feasible. However, there is also evidence that laparoscopic approach is effective, with minimal morbidity and no reported mortality. If a laparoscopic resection is contemplated, several factors including patient characteristics, tumor size, location, invasion as well as the surgeon’s experience need to be taken under consideration. The aim of the laparoscopic surgery is the same, aiming at the complete removal of the tumor, avoiding tumor rupture, as peritoneal seeding affects disease free period.

• #11 Gastrointestinal Stromal Tumors (GIST): Staging and Treatment | OncoLink

  https://www.oncolink.org/cancers/sarcomas/sarcoma-soft-tissue/gastrointestinal-stromal-tumors-gist-staging-and-treatment

  Surgery can be used to treat most cases of GIST. GIST are unlike other tumors because they are very soft and fragile. A surgeon must be very careful to not break or rupture the tumor. You need a surgeon familiar with GIST to do your surgery. The type of surgery you have will depend on the size of your tumor and where it is. […] The stage of your cancer will help your care team choose the best treatment for you. […] Your care team will make sure you are included in choosing your treatment plan. This can be overwhelming as you may be given a few options to choose from. It feels like an emergency, but you can take a few weeks to meet with different providers and think about your options and what is best for you. This is a personal decision. Friends and family can help you talk through the options and the pros and cons of each, but they cannot make the decision for you. You need to be comfortable with your decision this will help you move on to the next steps. If you ever have any questions or concerns, be sure to call your team.

• #12 Treating Gastrointestinal Stromal Tumors | American Cancer Society

  https://www.cancer.org/cancer/types/gastrointestinal-stromal-tumor/treating.html

  If you’ve been diagnosed with a gastrointestinal stromal tumor (GIST), your cancer care team will discuss your treatment options with you. It’s important to weigh the benefits of each treatment option against the possible risks and side effects. […] Not all GISTs need to be treated right away. But if treatment is needed, the main types used are surgery and targeted therapy. Other treatments, such as ablation, embolization, chemotherapy, and radiation, are used less often. […] The treatment of GISTs can be complex, so its important to be evaluated and treated by a team of doctors who have experience with this type of cancer. […] It’s important to discuss all treatment options, including their goals and possible side effects, with your doctors to help make the decision that best fits your needs.

• #13 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  Gastrointestinal stromal tumours (GIST) constitute a separate group of mesenchymal neoplasms of the gastrointestinal tract. […] Nursing practice with reference to GIST danger is connected with biopsychosocial interventions of perioperative, oncological and palliative procedures and involves the area of health education mainly oriented towards shaping preventive procedures which favour early disease detection and support therapy and recovery. […] During this period of disease, nursing care will be focused on, among others, patient preparation for diagnostic procedures CT, biopsy examinations or endoscopic ultrasonography. […] An important task in postoperative nursing care is prevention of postoperative complications including those resulting from the patient’s immobilization (pneumonia, thrombophlebitis).

• #14 Gastrointestinal Stromal Tumors (GISTs) Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/278845-treatment

  In cases of disseminated disease, consider palliative resection, because long-term survival has been reported in certain cases. Also consider resection in patients with recurrent disease that manifests as a solitary lesion in the liver or peritoneal cavity. […] Given the ability of imatinib to render initially inoperable GIST tumors resectable, there may be a role for cytoreductive surgery (R0 or R1 resection) in the setting of recurrent metastatic disease confined to the abdomen. […] Patients should have been on at least 6 months of therapy with imatinib or another tyrosine kinase inhibitor and have had either stable or partially responsive disease during this period. […] Postoperatively, patients receive nothing by mouth for varying durations, depending on the preference of the operating surgeon. Following nasogastric tube removal, patients can be started on a liquid diet and advanced to a full diet as tolerated.

• #15 Gastrointestinal Stromal Tumor (GIST) – Brigham and Women’s Hospital

  https://www.brighamandwomens.org/surgery/surgical-oncology/gastrointestional-stromal-tumor-sarcoma-gist?TRILIBIS_EMULATOR_UA=nsclpfpr%2Cnsclpfpr%2Cnsclpfpr%2Cnsclpfpr%2Cnsclpfpr%2Cnsclpfpr%2Cnsclpfpr%2Cnsclpfpr

  Gastrointestinal stromal tumors (GISTs) are rare tumors of the gastrointestinal tract. […] Surgery is the usual treatment if the tumor has not spread. […] Surgical oncologists at BWH are surgical specialists who are on the faculty at Harvard Medical School. […] Surgery which removes the tumor from your body is the primary treatment for a gastrointestinal stromal tumor (GIST) that hasn’t spread. […] The oncology surgeons at BWH are well known for having perfected many progressive surgical procedures including: […] You will receive a thorough diagnostic evaluation to determine your course of treatment. Careful monitoring and the involvement of an experienced surgical oncologist are important to the successful outcome for patients with GIST. […] After surgery, you will recover in the post-surgical care unit where you will receive comprehensive care by an experienced surgical and nursing staff.

• #16 Gastrointestinal Stromal Tumors (GISTs) Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/278845-treatment

  In cases of disseminated disease, consider palliative resection, because long-term survival has been reported in certain cases. Also consider resection in patients with recurrent disease that manifests as a solitary lesion in the liver or peritoneal cavity. […] Given the ability of imatinib to render initially inoperable GIST tumors resectable, there may be a role for cytoreductive surgery (R0 or R1 resection) in the setting of recurrent metastatic disease confined to the abdomen. […] Patients should have been on at least 6 months of therapy with imatinib or another tyrosine kinase inhibitor and have had either stable or partially responsive disease during this period. […] Postoperatively, patients receive nothing by mouth for varying durations, depending on the preference of the operating surgeon. Following nasogastric tube removal, patients can be started on a liquid diet and advanced to a full diet as tolerated.

• #17 Gastrointestinal Stromal Tumors | Treatment Update GIST | CancerCare

  https://www.cancercare.org/publications/136-treatment_update_gastrointestinal_stromal_tumors

  GIST (gastrointestinal stromal tumors) is a rare form of cancer, with approximately 5,000 cases diagnosed in the United States each year. […] The best treatment approach is often guided by an interdisciplinary team composed of medical oncologists, radiologists, surgeons and nurses. […] Surgery is the primary approach in the treatment of localized (non-metastatic) GIST. […] The need for adjuvant (post-surgery) treatment is determined based on the risk of the GIST recurring. […] Targeted therapies focus on specific molecules and cell mechanisms thought to be important for cancer cell survival and growth, taking advantage of what researchers have learned in recent years about how tumors grow. […] GIST is treated with medications called tyrosine kinase inhibitors (TKIs) which specifically block, or inhibit, KIT, slowing GIST cell growth.

• #18

  https://link.springer.com/article/10.1007/s10120-023-01381-6

  Gastrointestinal stromal tumours (GISTs) are soft-tissue sarcomas of the gastrointestinal tract. Surgery is the standard treatment for localised disease, but the risk of relapse and progression to more advanced disease is substantial. […] Imatinib is recommended in international guidelines as first-line therapy to reduce the risk of GIST relapse in high-risk patients, and for locally advanced, inoperable and metastatic disease. […] Unfortunately, imatinib resistance frequently occurs and, therefore, second-line (sunitinib) and third-line (regorafenib) TKIs have been developed. […] Treatment options are limited for patients with GIST that has progressed despite these therapies. […] In Japan, pimitespib, a heat shock protein 90 (HSP90) inhibitor, is now available as a fourth-line therapy for GIST.

• #19 Gastrointestinal Stromal Tumor (GIST) | Saint Luke’s Health System

  https://www.saintlukeskc.org/health-library/gastrointestinal-stromal-tumor-gist

  GIST can be treated in many ways. It grows differently in each person. The type of treatment that’s best for you depends on where the tumor is, how big it is, and if cells from the tumor have spread to other parts of your body. If the cancer has spread it is called metastasis. When GIST spreads, it often goes to the liver and the stomach lining. […] Talk with your healthcare providers about your treatment choices. Make a list of questions. Think about the benefits and possible side effects of each choice. Talk about your concerns with your healthcare provider before making a decision. […] It’s important to know which medicines you’re taking. Write down the names of your medicines. Ask your healthcare team how they work, how to take them, and what side effects they might have. […] Talk with your healthcare providers about what side effects to look for and when to call them. For instance, imatinib can cause itchy skin rashes that can lead to infections. Make sure you know what number to call with questions. Is there a different number for evenings, weekends, and holidays?

• #20 Gastrointestinal stromal tumor | World Journal of Surgical Oncology | Full Text

  https://wjso.biomedcentral.com/articles/10.1186/1477-7819-7-61

  Standard treatment for primary gastrointestinal stromal tumor (GIST) is complete surgical resection, with the aim to obtain negative microscopic margins over the organ of origin. In some cases, because of the anatomic site or the tumor size, complete resection is either not feasible or possible only through extensive procedures with expected major functional morbidity. Imatinib mesylate is a very active agent for tumor control in advanced and metastatic GIST. GISTs have a high risk of metastatic relapse. The usual site of recurrence is the liver (65%), the peritoneal surface (50%) and both (20%). GIST’s response to conventional chemotherapy is very poor (10%), while radiotherapy is only used for analgesic purposes or in cases of intra peritoneal hemorrhage. GISTs may show poor response to chemotherapy, but not to imatinib mesylate, also known as STI571 which was found to act as a powerful selective inhibitor of tyrosine kinases of PDGFR and of c-kit receptor. Imatinib was initially designed as a PDGFR inhibitor and its efficacy as a tyrosine kinase was assessed in chronic myeloid leukemia. The use of Imatinib mesylate in recurrent or metastatic, resectable or not GIST in prospective trial has shown response in 50% patients, and in approximately 75-85% patients have at least stable disease. The 2-year survival after Imatinib therapy is approximately 70% and 50% of the patients showed no progression of the disease. Imatinib interruption after 1 year is associated with a high risk of relapse, even for patients in complete remission. The treatment should continue until progression, intolerance or patient refusal. The treatment is usually well tolerated, but includes mild to moderate adverse effects such as edema (usually periorbital), nausea, muscle cramps, diarrhea, headache, dermatitis, fatigue, vitiligo, hypothyroidism, cutaneous pigmentation and abdominal pain. In patients with large bulky tumors, serious adverse events may include gastrointestinal, intraabdominal hemorrhages, cardiotoxicity and serosal inflammation. Other observed effects comprise neutropenia, leukopenia and abnormal liver function. The ideal dose of Imatinib is not determined, but the current data show no added benefit with doses greater than 400 mg/day. All studies on the dosage of Imatinib suggest that doses of 400-800 mg/day are safe, efficacious and patients tolerate it well.

• #21 Gastrointestinal Stromal Tumors (GIST) – Missouri Cancer Associates

  https://missouricancer.com/cancer_type/gastrointestinal-stromal-tumors-gist/

  Gastrointestinal stromal tumor is a disease in which abnormal cells form in the tissues of the gastrointestinal tract. […] Signs of gastrointestinal stromal tumors include blood in the stool or vomit. […] Tests that examine the GI tract are used to detect (find) and diagnose gastrointestinal stromal tumors. […] There are different types of treatment for patients with gastrointestinal stromal tumors. […] Four types of standard treatment are used: Surgery, Targeted therapy, Watchful waiting, Supportive care. […] If a GIST gets worse during treatment or there are side effects, supportive care is usually given. The goal of supportive care is to prevent or treat the symptoms of a disease, side effects caused by treatment, and psychological, social, and spiritual problems related to a disease or its treatment. […] Follow-up for GISTs that were removed by surgery may include CT scan of the liver and pelvis or watchful waiting. For GISTs that are treated with tyrosine kinase inhibitors, follow-up tests, such as CT, MRI, or PET scans, may be done to check how well the targeted therapy is working.

• #22 Gastrointestinal Stromal Tumor (GIST) | Saint Luke’s Health System

  https://www.saintlukeskc.org/health-library/gastrointestinal-stromal-tumor-gist

  It may be helpful to keep a diary of your side effects. Write down the physical, thinking, and emotional changes. A written list will make it easier for you to remember your questions when you go to your appointments. It will also make it easier for you to work with your healthcare team to make a plan to manage your side effects.

• #23 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  For patients with high and intermediate degrees of aggressiveness it is really important to undergo a thorough observation with computed tomography of the abdominopelvic cavity. […] Nursing care among others will focus on observation of the undesirable symptoms after the treatment with imatinib for patients with recommendations for molecularly targeted therapy with oral tyrosine kinase inhibitors in complementary treatment after GIST resection of significant risk of recurrence and as the treatment of choice in the case of non-surgical treatment of the lesions. […] The analysis of academic literature indicates that diagnosing a neoplasm and the treatment connected with it, which often causes mutilation, are reasons for the occurrence of symptoms of fear, depression and other mental health disorders.

• #24 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  Hence, taking nursing care at every stage perioperative, oncological, palliative the assessment of emotional functioning and supportive actions within this area seems to be also justified for patients with GIST. […] The professional nurse-patient relationship needs to be guided by principles of therapeutic communication, understood as conscious use of well-matched selected verbal and non-verbal announcements and thanks to them to influence positively behaviour and emotions of a subject of care.

• #25 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  Hence, taking nursing care at every stage perioperative, oncological, palliative the assessment of emotional functioning and supportive actions within this area seems to be also justified for patients with GIST. […] The professional nurse-patient relationship needs to be guided by principles of therapeutic communication, understood as conscious use of well-matched selected verbal and non-verbal announcements and thanks to them to influence positively behaviour and emotions of a subject of care.

• #26 Daily Life With GIST

  https://www.webmd.com/cancer/daily-life-with-gist

  Fatigue may occur, either from the cancer, or from treatment or both. If fatigue is present, exercise may be helpful to maintain physical and emotional fitness. […] To deal with the exhaustion from GIST, get enough rest every day. Sleep for at least 8 hours each night and take short naps during the day if needed. Schedule activities so as to do only as much as can be handled. […] Plan a work schedule around GIST. Work flexible hours and take breaks. If possible, take a leave of absence from work. Under the Family and Medical Leave Act, there may be eligibility for up to 12 weeks of leave because of the illness. […] Cancer affects more than just your body. Your emotional and mental health may be impacted as well. […] Ask for help when dealing with GIST. Family members, friends, spiritual organizations, online support communities, and cancer support groups can all be useful support systems. Reach out to a psychologist or therapist to help you deal with challenges.

• #27 Treating Gastrointestinal Stromal Tumors | American Cancer Society

  https://www.cancer.org/cancer/types/gastrointestinal-stromal-tumor/treating.html

  Remember that even if you choose not to treat the cancer, you can still get supportive care to help with pain or other symptoms. […] You and your family are encouraged to talk with your doctor or a member of your supportive care team about hospice care options, which include hospice care at home, a special hospice center, or other health care locations.

• #28 Daily Life With GIST

  https://www.webmd.com/cancer/daily-life-with-gist

  Eating the right foods is very important when you have GIST. […] The surgery used to treat GIST can cause food to move through the GI tract too quickly. This is known as „dumping syndrome.” As a result, you may find it is difficult to eat three large meals a day. If digestion is a problem, try to eat smaller mini-meals or portions every two to three hours. […] After surgery, vitamin and mineral deficiencies may develop due to a lack of absorption. Therefore, supplements may be helpful. Talk to your doctor about which supplements may be helpful for you. […] Limit sugary foods and excess fluids, as these can worsen symptoms. Adding more complex carbohydrates and protein to the diet may help you feel better. […] See a dietitian if possible. A dietitian can help you plan a menu of foods that are more agreeable to the GI tract.

• #29 Daily Life With GIST

  https://www.webmd.com/cancer/daily-life-with-gist

  Eating the right foods is very important when you have GIST. […] The surgery used to treat GIST can cause food to move through the GI tract too quickly. This is known as „dumping syndrome.” As a result, you may find it is difficult to eat three large meals a day. If digestion is a problem, try to eat smaller mini-meals or portions every two to three hours. […] After surgery, vitamin and mineral deficiencies may develop due to a lack of absorption. Therefore, supplements may be helpful. Talk to your doctor about which supplements may be helpful for you. […] Limit sugary foods and excess fluids, as these can worsen symptoms. Adding more complex carbohydrates and protein to the diet may help you feel better. […] See a dietitian if possible. A dietitian can help you plan a menu of foods that are more agreeable to the GI tract.

• #30 Daily Life With GIST

  https://www.webmd.com/cancer/daily-life-with-gist

  Eating the right foods is very important when you have GIST. […] The surgery used to treat GIST can cause food to move through the GI tract too quickly. This is known as „dumping syndrome.” As a result, you may find it is difficult to eat three large meals a day. If digestion is a problem, try to eat smaller mini-meals or portions every two to three hours. […] After surgery, vitamin and mineral deficiencies may develop due to a lack of absorption. Therefore, supplements may be helpful. Talk to your doctor about which supplements may be helpful for you. […] Limit sugary foods and excess fluids, as these can worsen symptoms. Adding more complex carbohydrates and protein to the diet may help you feel better. […] See a dietitian if possible. A dietitian can help you plan a menu of foods that are more agreeable to the GI tract.

• #31 What To Expect After GIST Surgery – Sarcoma Oncology Center

  https://sarcomaoncology.com/blog/what-to-expect-after-gist-surgery/

  Since there is a risk that a GIST may recur after treatment, we typically recommend follow-up visits every 3 to 6 months for several years, with the frequency possibly decreasing over time. […] We encourage gentle exercise to speed up a return to usual activities and improve quality of life. […] Overall, soft, nutrient-rich foods like broths, steamed vegetables, and lean protein are easy to digest and provide essential nutrients for healing. […] Recovery after GIST surgery is a gradual process, but with care and patience, you can return to your normal life.

• #32 Daily Life With GIST

  https://www.webmd.com/cancer/daily-life-with-gist

  Fatigue may occur, either from the cancer, or from treatment or both. If fatigue is present, exercise may be helpful to maintain physical and emotional fitness. […] To deal with the exhaustion from GIST, get enough rest every day. Sleep for at least 8 hours each night and take short naps during the day if needed. Schedule activities so as to do only as much as can be handled. […] Plan a work schedule around GIST. Work flexible hours and take breaks. If possible, take a leave of absence from work. Under the Family and Medical Leave Act, there may be eligibility for up to 12 weeks of leave because of the illness. […] Cancer affects more than just your body. Your emotional and mental health may be impacted as well. […] Ask for help when dealing with GIST. Family members, friends, spiritual organizations, online support communities, and cancer support groups can all be useful support systems. Reach out to a psychologist or therapist to help you deal with challenges.

• #33 Gastrointestinal Stromal Tumor (GIST)

  https://my.clevelandclinic.org/health/diseases/17031-gist-cancer-information

  Choose a wide variety of high-protein, low-fat foods and try to add leafy greens and fruits to your daily meals. […] Being sick can be stressful. As you recover from treatment, regular light exercise can help you manage stress. Talk to your healthcare provider before you go back to your exercise routine or start a new one. […] Using tobacco of any kind, including electronic cigarettes, increases your risk of developing new cancer or that a GIST will come back. […] If you have this condition, take some time to learn about this rare disease, including your treatment options. Treatment can often ease your symptoms and cure GIST. You’ll have questions, and your healthcare team will be there with answers, support and more.

• #34 What To Expect After GIST Surgery – Sarcoma Oncology Center

  https://sarcomaoncology.com/blog/what-to-expect-after-gist-surgery/

  Since there is a risk that a GIST may recur after treatment, we typically recommend follow-up visits every 3 to 6 months for several years, with the frequency possibly decreasing over time. […] We encourage gentle exercise to speed up a return to usual activities and improve quality of life. […] Overall, soft, nutrient-rich foods like broths, steamed vegetables, and lean protein are easy to digest and provide essential nutrients for healing. […] Recovery after GIST surgery is a gradual process, but with care and patience, you can return to your normal life.

• #35 Gastrointestinal Stromal Tumor (GIST)

  https://my.clevelandclinic.org/health/diseases/17031-gist-cancer-information

  Choose a wide variety of high-protein, low-fat foods and try to add leafy greens and fruits to your daily meals. […] Being sick can be stressful. As you recover from treatment, regular light exercise can help you manage stress. Talk to your healthcare provider before you go back to your exercise routine or start a new one. […] Using tobacco of any kind, including electronic cigarettes, increases your risk of developing new cancer or that a GIST will come back. […] If you have this condition, take some time to learn about this rare disease, including your treatment options. Treatment can often ease your symptoms and cure GIST. You’ll have questions, and your healthcare team will be there with answers, support and more.

• #36 Treating Gastrointestinal Stromal Tumors | American Cancer Society

  https://www.cancer.org/cancer/types/gastrointestinal-stromal-tumor/treating.html

  Remember that even if you choose not to treat the cancer, you can still get supportive care to help with pain or other symptoms. […] You and your family are encouraged to talk with your doctor or a member of your supportive care team about hospice care options, which include hospice care at home, a special hospice center, or other health care locations.

• #37 logo–sylvester

  https://umiamihealth.org/en/sylvester-comprehensive-cancer-center/treatments-and-services/bone-and-soft-tissue-sarcoma/soft-tissue-sarcomas/gastrointestinal-stromal-tumors

  Active Surveillance (Watchful Waiting): Sometimes your doctor may recommend waiting on treatment. This is called active surveillance, or watchful waiting. If we believe it is best to wait for more signs or symptoms before treating a GIST, we will continue monitoring your condition through regularly scheduled testing. […] Supportive Care: Supportive care may be offered if your tumor gets worse or if you have additional side effects of the tumor or your treatment. It can include pain management, psychological, social, and spiritual support. The goal is to help improve the quality of life for patients who have a serious or life-threatening disease. […] Radiation therapy is one supportive care treatment that could be recommended to relieve pain in patients with large GIST tumors that have spread. […] If your doctor believes you would benefit from enrollment in a clinical trial, he or she will discuss that option with you. Clinical trials are investigative studies of the newest available drugs, drug combinations or surgical approaches to treat a specific tumor.

• #38 Treating Gastrointestinal Stromal Tumors | American Cancer Society

  https://www.cancer.org/cancer/types/gastrointestinal-stromal-tumor/treating.html

  Remember that even if you choose not to treat the cancer, you can still get supportive care to help with pain or other symptoms. […] You and your family are encouraged to talk with your doctor or a member of your supportive care team about hospice care options, which include hospice care at home, a special hospice center, or other health care locations.

• #39 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  For patients with high and intermediate degrees of aggressiveness it is really important to undergo a thorough observation with computed tomography of the abdominopelvic cavity. […] Nursing care among others will focus on observation of the undesirable symptoms after the treatment with imatinib for patients with recommendations for molecularly targeted therapy with oral tyrosine kinase inhibitors in complementary treatment after GIST resection of significant risk of recurrence and as the treatment of choice in the case of non-surgical treatment of the lesions. […] The analysis of academic literature indicates that diagnosing a neoplasm and the treatment connected with it, which often causes mutilation, are reasons for the occurrence of symptoms of fear, depression and other mental health disorders.

• #40 What To Expect After GIST Surgery – Sarcoma Oncology Center

  https://sarcomaoncology.com/blog/what-to-expect-after-gist-surgery/

  Since there is a risk that a GIST may recur after treatment, we typically recommend follow-up visits every 3 to 6 months for several years, with the frequency possibly decreasing over time. […] We encourage gentle exercise to speed up a return to usual activities and improve quality of life. […] Overall, soft, nutrient-rich foods like broths, steamed vegetables, and lean protein are easy to digest and provide essential nutrients for healing. […] Recovery after GIST surgery is a gradual process, but with care and patience, you can return to your normal life.

• #41 Gastrointestinal Stromal Tumors (GIST) – Missouri Cancer Associates

  https://missouricancer.com/cancer_type/gastrointestinal-stromal-tumors-gist/

  Gastrointestinal stromal tumor is a disease in which abnormal cells form in the tissues of the gastrointestinal tract. […] Signs of gastrointestinal stromal tumors include blood in the stool or vomit. […] Tests that examine the GI tract are used to detect (find) and diagnose gastrointestinal stromal tumors. […] There are different types of treatment for patients with gastrointestinal stromal tumors. […] Four types of standard treatment are used: Surgery, Targeted therapy, Watchful waiting, Supportive care. […] If a GIST gets worse during treatment or there are side effects, supportive care is usually given. The goal of supportive care is to prevent or treat the symptoms of a disease, side effects caused by treatment, and psychological, social, and spiritual problems related to a disease or its treatment. […] Follow-up for GISTs that were removed by surgery may include CT scan of the liver and pelvis or watchful waiting. For GISTs that are treated with tyrosine kinase inhibitors, follow-up tests, such as CT, MRI, or PET scans, may be done to check how well the targeted therapy is working.

• #42 Gastrointestinal Stromal Tumors | Treatment Update GIST | CancerCare

  https://www.cancercare.org/publications/136-treatment_update_gastrointestinal_stromal_tumors

  Ablation therapy is a treatment that uses a locally-delivered energy source to destroy cancer cells. […] GIST that has spread to the liver can be treated with a minimally-invasive procedure called transarterial embolization (TAE). […] All cancer treatments can cause side effects. […] It’s important that you report any side effects that you experience to your health care team so they can help you manage them. […] Side effects of targeted therapies depend on the specific treatment being used and can include fluid retention, liver problems, heart problems, rashes, high blood pressure, increased risk of bleeding, cognitive difficulties, and problems with blood clotting and wound healing. […] Possible side effects of ablation therapy in the treatment of GIST include abdominal pain, liver infection and bleeding into the abdomen.

• #43 Gastrointestinal Stromal Tumors | Treatment Update GIST | CancerCare

  https://www.cancercare.org/publications/136-treatment_update_gastrointestinal_stromal_tumors

  Possible side effects of embolization include abdominal pain, fever, liver infection, gallbladder inflammation, blood clots in the liver’s main blood vessels and a reduction in overall liver function. […] Fatigue (extreme tiredness not helped by sleep) is one of the most common side effects of many cancer treatments. […] It can also be beneficial to speak with an oncology social worker or oncology nurse to help manage your fatigue. […] As you manage your cancer, it’s important to remember that you are a consumer of health care. […] Your primary care physician should be kept updated about your cancer treatment and any test results. […] Follow-up care is very important for people who have been treated for GIST, as there is always a chance that the GIST could recur (come back), even a number of years after treatment.

• #44 Gastrointestinal stromal tumour (GIST): British Sarcoma Group clinical practice guidelines | British Journal of Cancer

  https://www.nature.com/articles/s41416-024-02672-0

  Gastrointestinal stromal tumours (GISTs) are rare cancers, with an estimated unadjusted incidence of 1.5/100,000/year. […] The most common symptoms of GIST include upper gastrointestinal bleeding and anaemia, whilst larger tumours may present with abdominal pain/discomfort and a palpable mass. […] Treatment of GIST depends on the size and location of the tumour, the age and co-morbidity of the patient and the presence or absence of symptoms or complications such as perforation, bleeding or obstruction. Multidisciplinary treatment planning is essential. This should involve histopathologists, radiologists, surgeons and medical oncologists, as well as gastroenterologists and nuclear medicine specialists as applicable. Such teams are available in reference centres for sarcomas and GISTs, which treat a large number of GIST patients annually. Support staff, such as clinical nurse specialists, play a vital role and are not likely to be available, or have the appropriate expertise, outside specialised centres.

• #45 Gastrointestinal stromal tumour (GIST): British Sarcoma Group clinical practice guidelines | British Journal of Cancer

  https://www.nature.com/articles/s41416-024-02672-0

  Gastrointestinal stromal tumours (GISTs) are rare cancers, with an estimated unadjusted incidence of 1.5/100,000/year. […] The most common symptoms of GIST include upper gastrointestinal bleeding and anaemia, whilst larger tumours may present with abdominal pain/discomfort and a palpable mass. […] Treatment of GIST depends on the size and location of the tumour, the age and co-morbidity of the patient and the presence or absence of symptoms or complications such as perforation, bleeding or obstruction. Multidisciplinary treatment planning is essential. This should involve histopathologists, radiologists, surgeons and medical oncologists, as well as gastroenterologists and nuclear medicine specialists as applicable. Such teams are available in reference centres for sarcomas and GISTs, which treat a large number of GIST patients annually. Support staff, such as clinical nurse specialists, play a vital role and are not likely to be available, or have the appropriate expertise, outside specialised centres.

• #46 Gastrointestinal Stromal Tumors | Treatment Update GIST | CancerCare

  https://www.cancercare.org/publications/136-treatment_update_gastrointestinal_stromal_tumors

  GIST (gastrointestinal stromal tumors) is a rare form of cancer, with approximately 5,000 cases diagnosed in the United States each year. […] The best treatment approach is often guided by an interdisciplinary team composed of medical oncologists, radiologists, surgeons and nurses. […] Surgery is the primary approach in the treatment of localized (non-metastatic) GIST. […] The need for adjuvant (post-surgery) treatment is determined based on the risk of the GIST recurring. […] Targeted therapies focus on specific molecules and cell mechanisms thought to be important for cancer cell survival and growth, taking advantage of what researchers have learned in recent years about how tumors grow. […] GIST is treated with medications called tyrosine kinase inhibitors (TKIs) which specifically block, or inhibit, KIT, slowing GIST cell growth.

• #47 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  Gastrointestinal stromal tumours (GIST) constitute a separate group of mesenchymal neoplasms of the gastrointestinal tract. […] Nursing practice with reference to GIST danger is connected with biopsychosocial interventions of perioperative, oncological and palliative procedures and involves the area of health education mainly oriented towards shaping preventive procedures which favour early disease detection and support therapy and recovery. […] During this period of disease, nursing care will be focused on, among others, patient preparation for diagnostic procedures CT, biopsy examinations or endoscopic ultrasonography. […] An important task in postoperative nursing care is prevention of postoperative complications including those resulting from the patient’s immobilization (pneumonia, thrombophlebitis).

• #48 Gastrointestinal Stromal Tumor (GIST)

  https://my.clevelandclinic.org/health/diseases/17031-gist-cancer-information

  Choose a wide variety of high-protein, low-fat foods and try to add leafy greens and fruits to your daily meals. […] Being sick can be stressful. As you recover from treatment, regular light exercise can help you manage stress. Talk to your healthcare provider before you go back to your exercise routine or start a new one. […] Using tobacco of any kind, including electronic cigarettes, increases your risk of developing new cancer or that a GIST will come back. […] If you have this condition, take some time to learn about this rare disease, including your treatment options. Treatment can often ease your symptoms and cure GIST. You’ll have questions, and your healthcare team will be there with answers, support and more.

• #49 Gastrointestinal Stromal Tumor (GIST)

  https://my.clevelandclinic.org/health/diseases/17031-gist-cancer-information

  Gastrointestinal stromal tumors (GISTs) are rare cancerous tumors in your digestive system. Surgery to remove a GIST is the most common treatment. In some cases, surgery cures the condition. But these tumors can come back. […] Healthcare providers treat GISTs with surgery to remove the tumors. […] Oncologists typically treat GISTs with surgery. But treatment depends on what providers learn about the tumor from test results, including tumor size, location and whether the tumor is spreading from where it started (metastasis). […] For example, your oncology surgeon may be able to remove small tumors, and surgery may be the only treatment you’ll need. If a tumor is very large, your oncologist may order targeted therapy to shrink the tumor before surgery. […] Protecting your overall health during and after treatment is the best way you can take care of yourself:

• #50 Gastrointestinal Stromal Tumor (GIST)

  https://my.clevelandclinic.org/health/diseases/17031-gist-cancer-information

  Choose a wide variety of high-protein, low-fat foods and try to add leafy greens and fruits to your daily meals. […] Being sick can be stressful. As you recover from treatment, regular light exercise can help you manage stress. Talk to your healthcare provider before you go back to your exercise routine or start a new one. […] Using tobacco of any kind, including electronic cigarettes, increases your risk of developing new cancer or that a GIST will come back. […] If you have this condition, take some time to learn about this rare disease, including your treatment options. Treatment can often ease your symptoms and cure GIST. You’ll have questions, and your healthcare team will be there with answers, support and more.

• #51 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  Gastrointestinal stromal tumours (GIST) constitute a separate group of mesenchymal neoplasms of the gastrointestinal tract. […] Nursing practice with reference to GIST danger is connected with biopsychosocial interventions of perioperative, oncological and palliative procedures and involves the area of health education mainly oriented towards shaping preventive procedures which favour early disease detection and support therapy and recovery. […] During this period of disease, nursing care will be focused on, among others, patient preparation for diagnostic procedures CT, biopsy examinations or endoscopic ultrasonography. […] An important task in postoperative nursing care is prevention of postoperative complications including those resulting from the patient’s immobilization (pneumonia, thrombophlebitis).

• #52 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  Hence, taking nursing care at every stage perioperative, oncological, palliative the assessment of emotional functioning and supportive actions within this area seems to be also justified for patients with GIST. […] The professional nurse-patient relationship needs to be guided by principles of therapeutic communication, understood as conscious use of well-matched selected verbal and non-verbal announcements and thanks to them to influence positively behaviour and emotions of a subject of care.

• #53 Care for Gastrointestinal Stromal Tumors | Banner MD Anderson

  https://www.bannerhealth.com/services/cancer/cancer-type/stomach-cancer/symptoms-and-types/gist

  GIST surgery is the first treatment step for many people. The goal is to completely remove the tumor. […] Our team will work with you to manage these side effects and help you feel as comfortable as possible. […] After your treatment, regular follow-up care is important. You may have routine imaging tests and visits to your health care provider to check for any signs that cancer might be returning. […] If you or a loved one has been diagnosed with GIST, dont wait to get the care you need. At Banner MD Anderson, our team of surgeons, oncologists and geneticists are leaders in GIST care. They will help you understand your diagnosis, explore treatment options and provide the support you need through treatment and recovery.

• #54 Get Gastrointestinal Stromal Tumor Treatment | Cleveland Clinic

  https://my.clevelandclinic.org/services/gastrointestinal-stromal-tumor-treatment

  Your care team will work with you to find the best treatments for your needs and unique diagnosis. […] Surgery is the main treatment for gastrointestinal stromal tumors. Some GISTs can be treated very successfully by surgery if we can remove all of the tumor. […] We can also treat some GISTs with ablation and embolization. Ablation uses heat, cold or chemicals to destroy cancer cells. Embolization limits blood flow to the tumor to slow its growth. […] Targeted therapy is a new treatment that uses medications to target certain characteristics of GIST cells and destroy them. […] Our compassionate Cleveland Clinic providers are here to make sure you feel confident about moving forward with each step. Our team offers expert, personalized care and all the support you need physically, emotionally and mentally from day one.

• #55 Gastrointestinal Stromal Tumor (GIST) | Saint Luke’s Health System

  https://www.saintlukeskc.org/health-library/gastrointestinal-stromal-tumor-gist

  GIST can be treated in many ways. It grows differently in each person. The type of treatment that’s best for you depends on where the tumor is, how big it is, and if cells from the tumor have spread to other parts of your body. If the cancer has spread it is called metastasis. When GIST spreads, it often goes to the liver and the stomach lining. […] Talk with your healthcare providers about your treatment choices. Make a list of questions. Think about the benefits and possible side effects of each choice. Talk about your concerns with your healthcare provider before making a decision. […] It’s important to know which medicines you’re taking. Write down the names of your medicines. Ask your healthcare team how they work, how to take them, and what side effects they might have. […] Talk with your healthcare providers about what side effects to look for and when to call them. For instance, imatinib can cause itchy skin rashes that can lead to infections. Make sure you know what number to call with questions. Is there a different number for evenings, weekends, and holidays?

• #56 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  Hence, taking nursing care at every stage perioperative, oncological, palliative the assessment of emotional functioning and supportive actions within this area seems to be also justified for patients with GIST. […] The professional nurse-patient relationship needs to be guided by principles of therapeutic communication, understood as conscious use of well-matched selected verbal and non-verbal announcements and thanks to them to influence positively behaviour and emotions of a subject of care.

• #57 Gastrointestinal Stromal Tumor (GIST)

  https://my.clevelandclinic.org/health/diseases/17031-gist-cancer-information

  Gastrointestinal stromal tumors (GISTs) are rare cancerous tumors in your digestive system. Surgery to remove a GIST is the most common treatment. In some cases, surgery cures the condition. But these tumors can come back. […] Healthcare providers treat GISTs with surgery to remove the tumors. […] Oncologists typically treat GISTs with surgery. But treatment depends on what providers learn about the tumor from test results, including tumor size, location and whether the tumor is spreading from where it started (metastasis). […] For example, your oncology surgeon may be able to remove small tumors, and surgery may be the only treatment you’ll need. If a tumor is very large, your oncologist may order targeted therapy to shrink the tumor before surgery. […] Protecting your overall health during and after treatment is the best way you can take care of yourself:

• #58 Gastrointestinal Stromal Tumor (GIST)

  https://my.clevelandclinic.org/health/diseases/17031-gist-cancer-information

  Choose a wide variety of high-protein, low-fat foods and try to add leafy greens and fruits to your daily meals. […] Being sick can be stressful. As you recover from treatment, regular light exercise can help you manage stress. Talk to your healthcare provider before you go back to your exercise routine or start a new one. […] Using tobacco of any kind, including electronic cigarettes, increases your risk of developing new cancer or that a GIST will come back. […] If you have this condition, take some time to learn about this rare disease, including your treatment options. Treatment can often ease your symptoms and cure GIST. You’ll have questions, and your healthcare team will be there with answers, support and more.

• #59 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  Hence, taking nursing care at every stage perioperative, oncological, palliative the assessment of emotional functioning and supportive actions within this area seems to be also justified for patients with GIST. […] The professional nurse-patient relationship needs to be guided by principles of therapeutic communication, understood as conscious use of well-matched selected verbal and non-verbal announcements and thanks to them to influence positively behaviour and emotions of a subject of care.

• #60 Gastrointestinal stromal tumour (GIST): British Sarcoma Group clinical practice guidelines | British Journal of Cancer

  https://www.nature.com/articles/s41416-024-02672-0

  Gastrointestinal stromal tumours (GISTs) are rare cancers, with an estimated unadjusted incidence of 1.5/100,000/year. […] The most common symptoms of GIST include upper gastrointestinal bleeding and anaemia, whilst larger tumours may present with abdominal pain/discomfort and a palpable mass. […] Treatment of GIST depends on the size and location of the tumour, the age and co-morbidity of the patient and the presence or absence of symptoms or complications such as perforation, bleeding or obstruction. Multidisciplinary treatment planning is essential. This should involve histopathologists, radiologists, surgeons and medical oncologists, as well as gastroenterologists and nuclear medicine specialists as applicable. Such teams are available in reference centres for sarcomas and GISTs, which treat a large number of GIST patients annually. Support staff, such as clinical nurse specialists, play a vital role and are not likely to be available, or have the appropriate expertise, outside specialised centres.

• #61 Gastrointestinal Stromal Tumors | Treatment Update GIST | CancerCare

  https://www.cancercare.org/publications/136-treatment_update_gastrointestinal_stromal_tumors

  GIST (gastrointestinal stromal tumors) is a rare form of cancer, with approximately 5,000 cases diagnosed in the United States each year. […] The best treatment approach is often guided by an interdisciplinary team composed of medical oncologists, radiologists, surgeons and nurses. […] Surgery is the primary approach in the treatment of localized (non-metastatic) GIST. […] The need for adjuvant (post-surgery) treatment is determined based on the risk of the GIST recurring. […] Targeted therapies focus on specific molecules and cell mechanisms thought to be important for cancer cell survival and growth, taking advantage of what researchers have learned in recent years about how tumors grow. […] GIST is treated with medications called tyrosine kinase inhibitors (TKIs) which specifically block, or inhibit, KIT, slowing GIST cell growth.

• #62 Characteristics of gastrointestinal stromal tumours, diagnostic procedure and therapeutic management and main directions of nursing practice in gastrointestinal stromal tumours

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4355651/

  Gastrointestinal stromal tumours (GIST) constitute a separate group of mesenchymal neoplasms of the gastrointestinal tract. […] Nursing practice with reference to GIST danger is connected with biopsychosocial interventions of perioperative, oncological and palliative procedures and involves the area of health education mainly oriented towards shaping preventive procedures which favour early disease detection and support therapy and recovery. […] During this period of disease, nursing care will be focused on, among others, patient preparation for diagnostic procedures CT, biopsy examinations or endoscopic ultrasonography. […] An important task in postoperative nursing care is prevention of postoperative complications including those resulting from the patient’s immobilization (pneumonia, thrombophlebitis).

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