Materiały źródłowe

• #1 Esophagitis – Harvard Health

  https://www.health.harvard.edu/a_to_z/esophagitis-a-to-z

  The main symptoms of esophagitis are: Pain in the chest (behind the breastbone) or throat. The pain can be burning, heavy, or sharp. If acid reflux is the cause of esophagitis, the pain may be worse after meals or when you lie flat. Pain from esophagitis may be constant or may come and go. […] Swallowing problems, including worsening of the chest pain when you swallow or a feeling of food sticking in your chest after you swallow. […] Bleeding, seen as blood in vomit or as darkening of the stools. […] How long symptoms last depends on how easily their cause can be eliminated. Bad cases of reflux or resistant viruses, for example, might require several tries before the right medicine or treatment is found. In most cases, symptoms begin to improve within a few days of starting the right treatment. But it can take weeks for symptoms to go away completely. Esophagitis from an infection may be harder to cure if the immune system is severely weakened. […] Almost all cases of esophagitis can be cured. Some causes, such as acid reflux, may require long-term treatment.

• #1 Esophagitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/esophagitis/symptoms-causes/syc-20361224

  Esophagitis can cause painful, difficult swallowing. […] Common symptoms of esophagitis include: Trouble swallowing. Painful swallowing. Swallowed food becoming stuck in the esophagus, also known as food impaction. Burning pain in the chest called heartburn. It’s common to feel this pain behind the breastbone while eating. Stomach acid that backs up into the esophagus, also called acid reflux. […] One common symptom of eosinophilic esophagitis is food getting stuck in the esophagus after swallowing. This is called food impaction. Another common symptom is trouble swallowing, also called dysphagia. […] Without treatment, esophagitis can lead to changes in the structure of the esophagus. Complications can include: Scarring or narrowing of the esophagus, known as a stricture. Tearing of the lining of the esophagus. This can be due to retching or to healthcare professionals passing medical tools through an inflamed esophagus during endoscopy. A condition called Barrett esophagus in which the cells lining the esophagus are damaged from acid reflux. This raises the risk of cancer that starts in the esophagus, also called esophageal cancer.

• #1 Esophagitis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/174223-overview

  The common forms of esophagitis include reflux esophagitis, infectious esophagitis, pill esophagitis, eosinophilic esophagitis, and radiation and chemoradiation esophagitis. […] The prognosis is good with rapid diagnosis and proper treatment; ultimately, it depends on the severity of the underlying disease. […] Symptoms of reflux esophagitis (the most common type) may include the following: Heartburn, or dyspepsia (the most common symptom), Water brash, Regurgitation, Other common symptoms include upper abdominal discomfort, nausea, bloating, and fullness, Less common symptoms are dysphagia, odynophagia, cough, hoarseness, wheezing, and hematemesis, Chest pain indistinguishable from that of coronary artery disease (CAD). […] Patients with infectious esophagitis (eg, from Candida, cytomegalovirus [CMV], herpes simplex virus [HSV], or human immunodeficiency virus [HIV]) may be asymptomatic, but typical symptoms include the following: Onset of difficult or painful swallowing (ie, dysphagia or odynophagia), Heartburn, Retrosternal discomfort or pain, Nausea and vomiting, Fever and sepsis, Abdominal pain, Epigastric pain, Hematemesis (occasionally), Anorexia and weight loss, Cough.

• #1 Reflux Esophagitis

  https://oceanendosurgery.com/condition/reflux-esophagitis

  Reflux esophagitis is one of the complications that can come from having chronic heartburn and acid reflux, also known as gastroesophageal reflux disease (GERD). Esophagitis is inflammation that damages the lining of the esophagus and often causes painful or difficult swallowing and chest pain. The type of esophagitis caused by heartburn and acid reflux/GERD is known as reflux esophagitis. […] Symptoms of Reflux Esophagitis: Difficulty swallowing (dysphagia), Painful swallowing (odynophagia), Chest pain, Swallowed food becoming stuck in the esophagus, Nausea, Vomiting, Abdominal pain, Cough, Decreased appetite. […] If left untreated, reflux esophagitis may change the structure and function of the esophagus and lead to more serious complications such as Barretts esophagus, strictures and esophageal cancer.

• #1 Eosinophilic esophagitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/eosinophilic-esophagitis/symptoms-causes/syc-20372197

  Esophagitis is swelling and irritation, called inflammation, of the tissues that line the esophagus. […] This buildup, which is a reaction to foods, allergens or acid reflux, can inflame or injure the esophageal tissue. Damaged esophageal tissue can lead to difficulty swallowing or cause food to get stuck when you swallow. […] Signs and symptoms include: […] Difficulty swallowing, also called dysphagia […] Food getting stuck in the esophagus after swallowing, also known as impaction […] Chest pain that is often centrally located and does not respond to antacids […] Backflow of undigested food, known as regurgitation. […] You may have difficulty swallowing, called dysphagia. Or food may become stuck when you swallow. This is known as impaction. […] In some people, eosinophilic esophagitis can lead to the following: […] Scarring and narrowing of the esophagus. This makes it difficult to swallow and more likely that you will have food get stuck.

• #1 Esophagitis Clinical Presentation: History, Physical Examination

  https://emedicine.medscape.com/article/174223-clinical

  Infectious esophagitis is primarily seen in patients who are immunocompromised. The most common causes of infectious esophagitis are fungal (Candida species) and viral (herpes simplex virus and cytomegalovirus [CMV]). A history of immunosuppression, steroid therapy, recent antibiotic use, or systemic illness supports the diagnosis. Although patients may be asymptomatic, typical symptoms include the following: Onset of difficult or painful swallowing (ie, dysphagia, odynophagia), heartburn, retrosternal discomfort or pain, nausea, vomiting, fever, sepsis, abdominal pain, epigastric pain, hematemesis (occasionally), anorexia, weight loss (depends on chronicity and severity of underlying illness), cough. […] Candida esophagitis is usually manifested clinically by dysphagia and/or odynophagia in a patient with one or more predisposing factors for the condition. Symptoms are variable in severity, ranging from mild difficulty in swallowing to such intense odynophagia that the patient is unable to eat or swallow saliva. Other patients may present with chest pain or gastrointestinal (GI) tract bleeding; occasionally, patients are asymptomatic.

• #1 Esophagitis | Health Library | Memorial Health System

  https://www.mhsystem.org/health-library/con-20312402/

  Without treatment, esophagitis can lead to changes in the structure of the esophagus. Complications can include: Scarring or narrowing of the esophagus, known as a stricture. Tearing of the lining of the esophagus. […] Treatment for eosinophilic esophagitis involves staying away from the allergen that trigger symptoms. Treatment also involves easing the allergic reaction with medicines. […] Treatment for reflux esophagitis may include: Medicines available without a prescription. These include antacids; medicines called H-2-receptor blockers that lower stomach acid; and medicines called proton pump inhibitors that block stomach acid and heal the esophagus. […] Treatment for medicine-induced esophagitis involves not using the problem medicine when possible. It also involves lowering the risk of this condition with proper pill-taking habits.

• #1 Esophagitis: Causes, symptoms, and treatments

  https://www.medicalnewstoday.com/articles/9274

  Esophagitis is inflammation of the esophagus. Food and drink travel through the esophagus from the mouth to the stomach. Various health conditions can cause esophagitis, and it can lead to pain, nausea, and other symptoms. […] This inflammation can cause damage, and in some severe cases, it can cause bleeding, aspiration pneumonia, or stricture or tearing of the esophagus. […] These are the signs and symptoms most commonly linked to esophagitis: abdominal pain, pain and difficulty when swallowing, food becoming stuck in the esophagus, lack of appetite, nausea and possibly vomiting, cough, pain in the chest when eating, heartburn, mouth sores. […] In children and infants, symptoms include feeding difficulties, and possible failure to thrive, or difficulty gaining adequate weight. At this age, most patients are too young to describe their symptoms.

• #1 Esophagitis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK442012/

  The prognosis for most patients is good with prompt treatment, but ultimately the outcomes depend on the underlying cause. When esophagitis is recurrent, it can lead to anxiety and absenteeism from work because of the need to rule out other more serious causes of chest pain. Untreated esophagitis can lead to stricture formation and malnutrition. Both bleeding and perforation are also relatively common complications. Some patients may aspirate and develop pneumonitis or worsening of asthma. In most patients who do not change their lifestyle, recurrences are common, and thus lifelong therapy is required.

• #1 Esophagitis: Signs and Symptoms 

  https://www.health.com/esophagitis-symptoms-8645726

  Esophagitis causes inflammation of the esophagus, the muscular tube in your throat that carries foods and liquids from your mouth to your stomach. Inflammation can cause irritation and swelling of the esophageal tissues, leading to symptoms like difficulty swallowing, chest pain, and a sore throat. […] While some cases of esophagitis can develop suddenly and cause severe discomfort, it’s more common for symptoms to develop gradually and worsen over time. […] Common symptoms include difficulty swallowing, chest pain, and painful swallowing. While esophagitis symptoms can develop suddenly, in most cases, they develop gradually and worsen over time.

• #1 Erosive Esophagitis: Symptoms, Diagnosis, Causes, & More

  https://www.health.com/erosive-esophagitis-8647095

  Erosive esophagitis is a condition in which inflammation damages the lining of the esophagus, the tube connecting your mouth to your stomach. Erosive esophagitis typically develops from gastroesophageal reflux (GERD), when stomach acids flow back into the esophagus. Over time, stomach acids can erode (damage) the esophageal tissues and cause ulcers (sores). […] Symptoms like difficulty swallowing and chest pain are common with erosive esophagitis. […] Symptoms of erosive esophagitis are similar to those of GERD, including: Heartburn: This type of chest pain or discomfort may feel like a burning or squeezing sensation. Heartburn commonly develops after eating. Difficulty swallowing (dysphagia): Trouble swallowing food, liquids, or saliva may lead to food getting stuck in your throat. Painful swallowing (odynophagia): You may have a painful burning sensation when swallowing. Sore throat: A scratchy or raw-feeling sore throat can develop when stomach acids irritate the esophagus. Acid regurgitation: A burning sensation in the throat or sour taste in the mouth can occur when stomach contents flow into the esophagus. Globus sensation: This is the feeling that something is stuck in your throat. Increased salivation: Stomach acids in the esophagus can trigger increased saliva production in the mouth. Cough: Inflammation and irritation in the esophagus can lead to a chronic cough. Hoarseness: You can develop a strained or raspy voice from throat irritation. […] Difficulty swallowing, chest pain, and cough are common symptoms of erosive esophagitis.

• #1 Eosinophilic Esophagitis: What it Is, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/14321-eosinophilic-esophagitis

  Eosinophilic esophagitis symptoms may feel like symptoms of more common esophageal disorders. […] Damage to your esophagus from eosinophilic esophagitis may cause the following complications: esophageal perforation (rupture) and esophageal strictures. […] Eosinophilic esophagitis is a chronic and serious illness, but its not life-threatening. Youll probably need treatment for the rest of your life, like taking medication or avoiding specific food triggers.

• #1 Esophagitis: What It Is, Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/10138-esophagitis

  Esophageal stricture. Long-term inflammation of your esophageal tissues can cause scarring. Scar tissue can cause your esophagus to narrow (stricture), leading to swallowing difficulties. Severe swallowing difficulties may lead to dehydration, weight loss and malnutrition. […] Intestinal metaplasia. Intestinal metaplasia is a cellular change that can occur in your esophageal tissues. When it happens in your esophagus, it’s sometimes called Barrett’s esophagus. The tissues lining your esophagus adapt to constant inflammation by changing to resemble the lining of your intestines. This change can be a precursor to esophageal cancer. […] It depends on how easily the cause can be addressed. Some persistent cases may take some trial and error with different medications before landing on the right treatment. Once the right treatment begins, healing usually begins immediately. But it may take three to six weeks for esophagitis to heal completely. If the cause is a chronic condition, you may need long-term therapy to manage it.

• #1 Esophagitis: Symptoms & Treatment

  https://www.medicinenet.com/esophagitis/article.htm

  If untreated, esophagitis caused by GERD can lead to bleeding, ulcers, and chronic scarring. This scarring can narrow the esophagus, eventually interfering with the ability to swallow. A major complication that occurs in a significant portion of people with chronic or longstanding GERD, is Barrett’s esophagus, which increases the risk of esophageal cancer. Very few of those who develop Barrett’s esophagus will develop esophageal adenocarcinoma. […] The outlook for people with eosinophilic esophagitis is favorable. It is a chronic, relapsing condition, but not usually one that is life-threatening. Treatments are evolving using different immune modulators to decrease allergy-like reactions.

• #1 Esophagitis: What It Is, Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/10138-esophagitis

  Esophagitis may feel like: A sore throat. Heartburn. Difficulty swallowing. Chest pain. […] The pain may be mild to severe and may be constant or come and go. […] Depending on the cause and the severity, you might also notice: Acid reflux. Regurgitations. Food getting stuck in your throat. Indigestion. Feeding difficulties in children. Nausea and vomiting. Blood in your vomit. Mouth sores. […] Esophagitis is treatable, but severe esophagitis that goes untreated can lead to serious complications, such as: Ulcers. Ulcers are open sores that may occur in your esophagus lining. They can cause pain and bleeding. In rare cases, an ulcer that doesn’t heal may continue to wear all the way through your esophagus, making a hole (gastrointestinal perforation). This raises the risk of infections spreading from your esophagus to your chest cavity or to your bloodstream (septicemia).

• #1 Esophagitis – Augusta HealthSearchClose SearchSearch IconSearch IconClose Search IconMobile Menu IconMobile Menu Close IconInstagramFacebookTwitterYoutube

  https://www.augustahealth.com/disease/esophagitis/

  Left untreated, esophagitis can lead to changes in the structure of the esophagus. Possible complications include: Scarring or narrowing (stricture) of the esophagus, Tearing of the esophagus lining tissue from retching (if food gets stuck) or during endoscopy (due to inflammation), Barrett’s esophagus, characterized by changes to the cells lining the esophagus, increasing your risk of esophageal cancer.

• #1 Eosinophilic Esophagitis: What it Is, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/14321-eosinophilic-esophagitis

  Eosinophilic esophagitis is an inflammation of the esophagus caused by an overabundance of certain white blood cells. Among the symptoms of eosinophilic esophagitis are heartburn, chest pain and difficulty swallowing. […] Symptoms include heartburn and chest pain. […] Without treatment, this inflammation can lead to scar tissue and narrowing in your esophagus, so you have difficulty swallowing. […] Eosinophilic esophagitis may cause heartburn, chest discomfort and regurgitation (spit up of food). […] Older children and adults may have difficulty swallowing (dysphagia), heartburn or chest discomfort. […] Symptoms that are less common but that may affect people of any age include abdominal (belly) pain. […] Food impaction may be a medical emergency and require a trip to the emergency room because it can tear a hole in your esophagus (esophageal rupture or perforation).

• #1 Eosinophilic Oesophagitis (EoE) – Australasian Society of Clinical Immunology and Allergy (ASCIA)

  https://www.allergy.org.au/patients/food-other-adverse-reactions/eosinophilic-oesophagitis

  The symptoms of EoE may be different in children and adults. […] Symptoms of EoE in children include: Slow eating, Food impaction/food bolus obstruction (FBO) which is when food gets stuck in the oesophagus, Choking or gagging on food, Regurgitation of food, Abdominal (stomach) pain. […] Symptoms of EoE in adolescents and adults include: Trouble swallowing, Food impaction/FBO, Regurgitation of foods, Severe acid reflux (heartburn) that does not respond to medications, Chest pain when eating, Chewing longer and drinking more water with solid food/s. […] EoE symptoms in infants (babies) may get better in the first few years of life, particularly if only one or two foods are the cause. If symptoms first appear in older children and adults, they are usually lifelong. […] If left untreated, around 30-50% of children and adults with EoE will eventually get food impaction/FBO, which may need to be removed in hospital. This can cause permanent scarring and narrowing (stricture) of the oesophagus.

• #1 Eosinophilic Esophagitis: Signs, Symptoms, and Complications

  https://www.verywellhealth.com/eosinophilic-esophagitis-signs-symptoms-5207805

  Eosinophilic esophagitis is a rare chronic condition that affects the muscular tube that connects the mouth to the stomach, known as the esophagus. People who have eosinophilic esophagitis experience an overgrowth of eosinophils, which are white blood cells, inside the esophagus. […] The most common symptom of eosinophilic esophagitis is difficulty swallowing. […] Symptoms are caused by this chronic inflammation in the lining of the esophagus. Common symptoms in adults include: Difficulty swallowing, known as dysphagia; Painful swallowing; Feeling as though food is getting stuck in the throat; Vomiting or regurgitation of food; Chest pain or heartburn; Difficulty eating hard or dense foods. […] A 2020 study found that up to 50% of adults who seek treatment for food impaction are eventually diagnosed with eosinophilic esophagitis.

• #1 Eosinophilic Esophagitis: Symptoms & Causes | NewYork-Presbyterian

  https://www.nyp.org/digestive/esophageal-diseases/eosinophilic-esophagitis

  Eosinophilic esophagitis symptoms may differ from person to person and also between infants, children, and adults. […] Infants with EOE symptoms may experience: Difficulty feeding, Poor weight gain and growth, Reflux (spitting up) that does not respond to medication, Trouble sleeping. […] Symptoms of EOE in children may include the same symptoms, as well as: Poor appetite, Stomach pain, Trouble swallowing. […] EOE symptoms in adults may include: Difficulty swallowing and a feeling of food stuck in the throat, Heartburn, Upset stomach or vomiting. […] Effective treatment of eosinophilic esophagitis can reduce your risk of complications, some of which may require an emergency endoscopy procedure to relieve an obstruction. […] Possible complications of EOE include: Narrowing of the esophagus (strictures) with formation of scar tissue, Food getting stuck in the esophagus (impaction), Damage to the esophageal tissue, such as perforations or tears.

• #1 Patient-reported symptoms and burden of eosinophilic esophagitis: evidence from real-world clinical practice | BMC Gastroenterology | Full Text

  https://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-024-03334-4

  Eosinophilic esophagitis is a chronic inflammatory disorder of the esophagus. […] Symptoms of EoE include dysphagia, food impaction, abdominal pain, nausea, and vomiting. […] The severity of eosinophilic esophagitis was mild in more patients overall (69%) versus those with dysphagia despite treatment (48%). […] Common patient-reported symptoms were dysphagia (70% and 86%) and heartburn/acid reflux (55% and 49%), and common physician-reported symptoms were dysphagia (75% and 91%) and food impaction (46% and 52%). […] Patients reported slightly more days with symptoms, higher impacts on activities of daily living, and slightly higher anxiety or depression in the dysphagia-despite-treatment population versus the overall population. […] Eosinophilic esophagitis presents severe symptoms and comorbidities that substantially impact patients well-being and quality of life.

• #1 Esophagitis: Learn About Symptoms, Causes, & Treatment – BuzzRx

  https://www.buzzrx.com/blog/esophagitis

  The symptoms of esophagitis can vary depending on the severity and underlying cause. Common symptoms of esophagitis include painful or difficulty swallowing, chest pain, reflux, regurgitation, and the sensation of food stuck in the throat. […] Symptoms of esophagitis include a burning chest pain and painful or difficulty swallowing due to the inflamed esophagus. […] The symptoms of esophagitis, such as chest pain and difficulty swallowing, can impact daily life, including decreased work productivity, sleep disturbances, and impact on social life by limiting the ability to eat. […] Seek emergency medical care if you have the following symptoms: Chest pain that does not go away within a few minutes or keeps coming back. […] Treatment for esophagitis depends on the underlying cause. Esophagitis treatments can help to treat or cure the underlying condition, manage symptoms, and lower the risk of esophagitis complications.

• #1 Patient-reported symptoms and burden of eosinophilic esophagitis: evidence from real-world clinical practice | BMC Gastroenterology | Full Text

  https://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-024-03334-4

  Patients with dysphagia despite treatment experience higher symptom and HRQOL burden with dysphagia itself and anxiety or depression per EQ-5D-3 L responses, further underscoring the urgent need for novel, targeted treatment for patients with EoE. […] The most common patient-reported symptoms prior to diagnosis were dysphagia (70% and 86%) and heartburn/acid reflux (55% and 49%). […] On average, patients in the dysphagia-despite-treatment population reported slightly more days per week with symptoms versus the overall population. […] Patients reported higher 7-day impacts on activities of daily living in the dysphagia-despite-treatment versus the overall population. […] EoE is a multisymptomatic, chronic allergic inflammatory disease of the esophagus that can greatly hinder a patients overall well-being and quality of life, especially related to diet and eating, despite standard-of-care treatments.

• #1 Esophagitis: Types, Symptom, and Risk Factors

  https://www.healthline.com/health/esophagitis

  Symptoms of esophagitis include: trouble swallowing (dysphagia), sore throat, heartburn, pain when you swallow (odynophagia), hoarse voice, acid reflux, chest pain (worse with eating), nausea, vomiting, abdominal pain, decrease in appetite, cough. […] If left untreated, esophagitis may lead to ulcers, scarring, and severe narrowing of the esophagus which can be a medical emergency. Speak with a doctor if you experience any symptoms. […] Esophagitis may take up to 8 weeks to heal with proper treatment. However, chronic esophagitis may require life-long management.

• #1 Eosinophilic Esophagitis

  https://www.aaaai.org/conditions-treatments/related-conditions/eosinophilic-esophagitis

  Once the causative food(s) is (are) identified and removed from a persons diet, esophageal inflammation and symptoms generally improve in a few weeks. Symptoms may not always reflect whether inflammation is present in the esophagus so additional biopsies are necessary to see if a diet is working and prove which food(s) is (are) causing EoE.

• #1 Esophagitis – infectious Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/diseases-conditions/esophagitis-infectious

  Esophagitis is a term for any inflammation, irritation, or swelling of the esophagus. This is the tube that carries food and liquids from the mouth to the stomach. […] Infectious esophagitis is an infection of the esophagus from viruses, bacteria, fungi, or yeast. This most often occurs in people with a weak immune system. […] Symptoms of infectious esophagitis include: Difficulty swallowing, Painful swallowing, Fever and chills, Yeast infection of the tongue and lining of the mouth (oral thrush), Sores in the mouth or back of the throat (with herpes or CMV). […] In people with a healthy immune system, esophagitis often goes away on its own. People with a weak immune system may take longer to get better.

• #1 Esophagitis: Symptoms & Treatment

  https://www.medicinenet.com/esophagitis/article.htm

  Esophagitis or inflamed esophagus symptoms include hoarseness, mouth sores, and bad breath. […] Esophagitis symptoms may include the following: Bad breath (halitosis), A feeling of food getting stuck while swallowing, Difficult and/or painful swallowing, Pain in the middle of the chest, often radiating to the back, is usually associated with swallowing or occurring soon after a meal, An unpleasant taste in the mouth, Indigestion, Heartburn, Acid reflux, Sore throat, Hoarseness, Cough, Mouth sores, Nausea, Vomiting, Abdominal pain or indigestion. […] The prognosis for esophagitis often depends on the underlying cause. Esophagitis caused by infection or inflammation is generally treatable with medications, diet or behavioral changes, and in some cases, surgery. Most people can recover fully, while some have chronic inflammation that is managed with long-term medical treatment. Esophagitis caused by reflux, while often manageable, can recur frequently. Many people with reflux require medication or other treatments to prevent relapses.

• #1 Esophagitis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/174223-overview

  Complications of esophagitis may include the following: Bleeding and stricture formation, Barrett esophagus, Perforation with mediastinitis (rare), Volume depletion and weight loss, Laryngitis, aspiration pneumonitis, and bronchospasm, In infants, failure to thrive and apnea. […] The prognosis is good with rapid diagnosis and proper treatment. Ultimately, prognosis depends on the underlying disease process. […] Complicated esophagitis may lead to esophageal strictures (typically long, smooth, tapered areas of narrowing), malnutrition, and, rarely, perforation or bleeding. […] Severe esophagitis may lead to dysphagia, pain, odynophagia, and malnutrition. Rarely, life-threatening bleeding occurs and may lead to death. […] Recurrence is a frequent problem in patients with reflux. Many patients require maintenance therapy to prevent relapse of symptoms.

• #1 Esophagitis | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/esophagitis

  Esophagitis is inflammation of the lining of the esophagus, the muscular tube that connects the pharynx (throat) to the stomach. In children, it is usually the result of gastroesophageal reflux disease (GERD), eosinophilic esophagitis, infection, or ingestion of corrosive substances (such as cleaning products or battery acid). Over time, esophagitis can lead to dysmotility, narrowing of the esophagus, or precancerous changes of the esophagus (Barrett’s esophagus). […] Esophagitis is inflammation of the lining of the esophagus. This can lead to a variety of symptoms in children, including: Heartburn, Chest pain, Coughing, Dysphagia (difficulty swallowing), Pain when swallowing, Food getting stuck, Crossing growth curves, Avoidance of food textures. […] Left untreated, esophagitis may cause complications, such as: Bleeding, Chronic respiratory illnesses, Failure to thrive, Esophageal strictures, narrowing of the esophagus that can make it difficult to swallow, Barrett’s esophagus, a precancerous condition caused by long-term esophageal inflammation like GERD.

• #1 Esophagitis Clinical Presentation: History, Physical Examination

  https://emedicine.medscape.com/article/174223-clinical

  The most common complaint in patients with esophagitis is heartburn (dyspepsia), a burning sensation in the midchest caused by the contact of stomach acid with the esophageal mucosa. Symptoms often are maximal while the person is supine, bending over, or wearing tight clothing or after the person has eaten a large meal. The patient may complain of water brash, a bitter taste of refluxed gastric contents often associated with heartburn. […] Other common symptoms of esophagitis include upper abdominal discomfort, nausea, bloating, and fullness. Less common symptoms of esophagitis include dysphagia, odynophagia, cough, hoarseness, wheezing, and hematemesis. […] The patient may experience chest pain indistinguishable from that of coronary artery disease. Pain is often midsternal, with radiation to the neck or arm, and may be associated with shortness of breath and diaphoresis. Chest pain may be relieved with nitrates if esophageal spasm is involved, further confounding the diagnostic evaluation.

• #1 Gastroesophageal Reflux Disease (GERD) – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK554462/

  Approximately 10% of patients with reflux develop Barrett esophagus, a precursor for adenocarcinoma of the esophagus. […] Complications associated with GERD are listed below. […] Barrett esophagus occurs in 5% to 15% of patients with reflux esophagitis. This complication is more likely to occur in White male patients with severe reflux esophagitis who have had the symptoms for a longer duration and are older than 50.

• #2 Esophagitis: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/001153.htm

  Esophagitis is a condition in which the lining of the esophagus becomes swollen, inflamed, or irritated. […] Symptoms may include: Cough, Difficulty swallowing, Painful swallowing, Heartburn (acid reflux), Hoarseness, Sore throat. […] The infection or irritation may cause the food pipe to become inflamed. Sores called ulcers may form. […] Most of the time, the disorders that cause swelling and inflammation of the food pipe, respond to treatment. […] If not treated, this condition may cause severe discomfort. Scarring (stricture) of the food pipe may develop. This can cause swallowing problems. […] A condition called Barrett esophagus (BE) can develop after years of GERD. Rarely, BE may lead to cancer of the food pipe.

• #2 Esophagitis: What It Is, Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/10138-esophagitis

  Esophagitis may feel like: A sore throat. Heartburn. Difficulty swallowing. Chest pain. […] The pain may be mild to severe and may be constant or come and go. […] Depending on the cause and the severity, you might also notice: Acid reflux. Regurgitations. Food getting stuck in your throat. Indigestion. Feeding difficulties in children. Nausea and vomiting. Blood in your vomit. Mouth sores. […] Esophagitis is treatable, but severe esophagitis that goes untreated can lead to serious complications, such as: Ulcers. Ulcers are open sores that may occur in your esophagus lining. They can cause pain and bleeding. In rare cases, an ulcer that doesn’t heal may continue to wear all the way through your esophagus, making a hole (gastrointestinal perforation). This raises the risk of infections spreading from your esophagus to your chest cavity or to your bloodstream (septicemia).

• #2 Esophagitis Clinical Presentation: History, Physical Examination

  https://emedicine.medscape.com/article/174223-clinical

  The most common complaint in patients with esophagitis is heartburn (dyspepsia), a burning sensation in the midchest caused by the contact of stomach acid with the esophageal mucosa. Symptoms often are maximal while the person is supine, bending over, or wearing tight clothing or after the person has eaten a large meal. The patient may complain of water brash, a bitter taste of refluxed gastric contents often associated with heartburn. […] Other common symptoms of esophagitis include upper abdominal discomfort, nausea, bloating, and fullness. Less common symptoms of esophagitis include dysphagia, odynophagia, cough, hoarseness, wheezing, and hematemesis. […] The patient may experience chest pain indistinguishable from that of coronary artery disease. Pain is often midsternal, with radiation to the neck or arm, and may be associated with shortness of breath and diaphoresis. Chest pain may be relieved with nitrates if esophageal spasm is involved, further confounding the diagnostic evaluation.

• #2 Reflux Esophagitis: Causes, Symptoms, Risk Factors & More

  https://www.dhcoftx.com/conditions/reflux-esophagitis/

  Reflux esophagitis is one of the complications that can come from having chronic heartburn and acid reflux, also known as gastroesophageal reflux disease (GERD). Additionally, esophagitis is inflammation that damages the lining of the esophagus and often causes painful or difficult swallowing and chest pain. Additionally, the type of esophagitis caused by heartburn and acid reflux/GERD is known as reflux esophagitis. […] Symptoms of Reflux Esophagitis: Difficulty swallowing (dysphagia), Painful swallowing (odynophagia), Chest pain, Swallowed food becoming stuck in the esophagus, Nausea, Vomiting, Abdominal pain, Cough, Decreased appetite. […] If left untreated, it may change the structure and function of the esophagus and lead to more serious complications such as Barretts esophagus, strictures and esophageal cancer.

• #2 Eosinophilic Esophagitis: What it Is, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/14321-eosinophilic-esophagitis

  Eosinophilic esophagitis is an inflammation of the esophagus caused by an overabundance of certain white blood cells. Among the symptoms of eosinophilic esophagitis are heartburn, chest pain and difficulty swallowing. […] Symptoms include heartburn and chest pain. […] Without treatment, this inflammation can lead to scar tissue and narrowing in your esophagus, so you have difficulty swallowing. […] Eosinophilic esophagitis may cause heartburn, chest discomfort and regurgitation (spit up of food). […] Older children and adults may have difficulty swallowing (dysphagia), heartburn or chest discomfort. […] Symptoms that are less common but that may affect people of any age include abdominal (belly) pain. […] Food impaction may be a medical emergency and require a trip to the emergency room because it can tear a hole in your esophagus (esophageal rupture or perforation).

• #2 Esophagitis Clinical Presentation: History, Physical Examination

  https://emedicine.medscape.com/article/174223-clinical

  Herpes esophagitis is most commonly seen in immunocompromised patients with acquired immunodeficiency syndrome (AIDS), an underlying malignancy, or a debilitating illness or in patients who have been treated with radiation, steroids, or chemotherapy. However, it occasionally occurs as an acute self-limiting disease in otherwise healthy patients who have no underlying immunologic problems. Patients with herpes esophagitis typically present with an acute onset of severe odynophagia. Other presenting findings include dysphagia, chest pain, and upper GI tract bleeding. […] CMV esophagitis is usually manifested by the development of severe odynophagia, dysphagia, or both, in patients with AIDS. In affected individuals, evidence of CMV infection may be present in other organs or tissues, such as the retina, liver, and colon. Occasionally, odynophagia may be so severe that the patients develop sitophobia (fear of eating), and parenteral alimentation is required.

• #2 Esophagitis | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/esophagitis

  Esophagitis is inflammation of the lining of the esophagus, the muscular tube that connects the pharynx (throat) to the stomach. In children, it is usually the result of gastroesophageal reflux disease (GERD), eosinophilic esophagitis, infection, or ingestion of corrosive substances (such as cleaning products or battery acid). Over time, esophagitis can lead to dysmotility, narrowing of the esophagus, or precancerous changes of the esophagus (Barrett’s esophagus). […] Esophagitis is inflammation of the lining of the esophagus. This can lead to a variety of symptoms in children, including: Heartburn, Chest pain, Coughing, Dysphagia (difficulty swallowing), Pain when swallowing, Food getting stuck, Crossing growth curves, Avoidance of food textures. […] Left untreated, esophagitis may cause complications, such as: Bleeding, Chronic respiratory illnesses, Failure to thrive, Esophageal strictures, narrowing of the esophagus that can make it difficult to swallow, Barrett’s esophagus, a precancerous condition caused by long-term esophageal inflammation like GERD.

• #2 Esophagitis: What It Is, Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/10138-esophagitis

  Esophageal stricture. Long-term inflammation of your esophageal tissues can cause scarring. Scar tissue can cause your esophagus to narrow (stricture), leading to swallowing difficulties. Severe swallowing difficulties may lead to dehydration, weight loss and malnutrition. […] Intestinal metaplasia. Intestinal metaplasia is a cellular change that can occur in your esophageal tissues. When it happens in your esophagus, it’s sometimes called Barrett’s esophagus. The tissues lining your esophagus adapt to constant inflammation by changing to resemble the lining of your intestines. This change can be a precursor to esophageal cancer. […] It depends on how easily the cause can be addressed. Some persistent cases may take some trial and error with different medications before landing on the right treatment. Once the right treatment begins, healing usually begins immediately. But it may take three to six weeks for esophagitis to heal completely. If the cause is a chronic condition, you may need long-term therapy to manage it.

• #2 Eosinophilic Esophagitis – Gastrointestinal Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/gastrointestinal-disorders/esophageal-and-swallowing-disorders/eosinophilic-esophagitis

  Eosinophilic esophagitis is a chronic immune-mediated disease of the esophagus resulting in eosinophil-predominant inflammation of the esophagus; it can cause reflux-like symptoms, dysphagia, and food impaction. […] Symptoms of gastroesophageal reflux disease (GERD), such as heartburn, may occur. […] The cause of eosinophilic esophagitis is likely an immune response to dietary antigens in patients with genetic susceptibility; environmental allergens may also play a role. Untreated chronic esophageal inflammation ultimately can lead to esophageal narrowing and strictures. […] Infants and children may present with food refusal, vomiting, weight loss, abdominal pain, and/or chest pain. […] In adults, esophageal food impaction is sometimes the first manifestation, and most patients have dysphagia.

• #2 Gastroesophageal reflux disease | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/stomach-liver-and-gastrointestinal-tract/gastro-oesophageal-reflux-disease-gord/

  Symptoms of GORD can include: […] a sore, inflamed oesophagus (oesophagitis) […] The main symptoms of gastro-oesophageal reflux disease (GORD) are heartburn and acid reflux. […] If you have GORD, you may also experience: […] a sore, inflamed oesophagus (oesophagitis) […] The stomach acid that leaks into the oesophagus in people with GORD can damage the lining of the oesophagus (oesophagitis), which can cause ulcers to form. […] Repeated damage to the oesophagus by stomach acid can also cause it to become scarred and narrowed. […] This is known as oesophageal stricture and it can make swallowing difficult and painful. […] Repeated episodes of GORD can sometimes lead to changes in the cells in the lining of your lower oesophagus. This is known as Barretts oesophagus. […] Its estimated that about 1 in every 10 people with GORD will develop Barretts oesophagus, usually after many years. […] Symptoms of oesophageal cancer include: […] difficulty swallowing […] Speak to your doctor if you experience any swallowing difficulties, or any other unusual or persistent symptoms.

• #2 Gastroesophageal Reflux Disease (GERD) – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK554462/

  Approximately 10% of patients with reflux develop Barrett esophagus, a precursor for adenocarcinoma of the esophagus. […] Complications associated with GERD are listed below. […] Barrett esophagus occurs in 5% to 15% of patients with reflux esophagitis. This complication is more likely to occur in White male patients with severe reflux esophagitis who have had the symptoms for a longer duration and are older than 50.

• #2 Erosive Esophagitis: Symptoms, Causes & Treatment – Tua Saúde

  https://www.tuasaude.com/en/erosive-esophagitis/

  Erosive esophagitis classified as LA Grade C or LA Grade D is often recurrent and poses a greater risk for esophageal cancer. […] In most cases, erosive esophagitis occurs as a result of untreated esophagitis. Chronic inflammation can lead to the formation of wounds and tissue damage along the esophageal lining. […] Gastroesophageal reflux disease (or GERD) can also lead to erosive esophagitis. This condition is characterized by the backflow of stomach acid into the esophagus, which irritates the tissue and causes damage. […] Treatment for erosive esophagitis depends on the underlying cause. […] Surgical repair is only recommended for tissue damage that does not improve, if symptoms persist, and if other treatment options have been exhausted.

• #2 EoE – Apfed

  https://apfed.org/about-ead/egids/eoe/

  Regular monitoring of EoE is important because if it isn’t treated properly, ongoing inflammation can cause scar tissue to form in the esophagus. This can cause parts of the esophagus to narrow, leading to problems swallowing. It also raises the risk of food getting stuck in the esophagus, which can be painful and require a doctor’s help to remove. […] In some patients, EoE is complicated by the development of esophageal narrowing (strictures) which may cause food to lodge in the esophagus (impaction). It can also make eating very difficult and uncomfortable for children and adults. It is not clear how long EoE has to exist before strictures form. However, since the natural history of EoE is only emerging, careful monitoring and long-term follow-up is advised.

• #2 Eosinophilic Esophagitis: Signs, Symptoms, and Complications

  https://www.verywellhealth.com/eosinophilic-esophagitis-signs-symptoms-5207805

  Eosinophilic esophagitis can lead to life-threatening complications if left untreated. When food becomes lodged in the esophagus, this is known as food impaction. Food impaction makes it impossible to eat or drink and must be treated right away. […] Eosinophilic esophagitis is a chronic condition and can lead to complications over time. Possible complications include: Food impaction: This occurs when food becomes firmly stuck in the esophagus; Narrowing of the esophagus: Over time, eosinophilic esophagitis can cause scarring and narrowing of the esophagus. This may make swallowing food even more difficult; Esophageal tear: Eosinophilic esophagitis causes inflammation in the esophagus, and this may lead to tearing in the lining known as a perforation. […] Eosinophilic esophagitis is considered to be a chronic condition. While it can be managed and controlled, there is no known cure. […] Eosinophilic esophagitis is a chronic immune condition that is characterized by a buildup of eosinophils in the esophagus. This buildup of white blood cells causes inflammation and leads to symptoms such as difficulty swallowing (dysphagia), heartburn, chest pain, and food impaction. Children experience slightly different symptoms, including nausea, vomiting, food regurgitation, and an inability to eat or drink.

• #2 Patient-reported symptoms and burden of eosinophilic esophagitis: evidence from real-world clinical practice | BMC Gastroenterology | Full Text

  https://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-024-03334-4

  Patients with dysphagia despite treatment experience higher symptom and HRQOL burden with dysphagia itself and anxiety or depression per EQ-5D-3 L responses, further underscoring the urgent need for novel, targeted treatment for patients with EoE. […] The most common patient-reported symptoms prior to diagnosis were dysphagia (70% and 86%) and heartburn/acid reflux (55% and 49%). […] On average, patients in the dysphagia-despite-treatment population reported slightly more days per week with symptoms versus the overall population. […] Patients reported higher 7-day impacts on activities of daily living in the dysphagia-despite-treatment versus the overall population. […] EoE is a multisymptomatic, chronic allergic inflammatory disease of the esophagus that can greatly hinder a patients overall well-being and quality of life, especially related to diet and eating, despite standard-of-care treatments.

• #2 Esophagitis – Wikipedia

  https://en.wikipedia.org/wiki/Esophagitis

  The prognosis for a person with esophagitis depends on the underlying causes and conditions. If a patient has a more serious underlying cause such as a digestive system or immune system issue, it may be more difficult to treat. Normally, the prognosis would be good with no serious illnesses. If there are more causes than one, the prognosis could move to fair.

• #2 Esophagitis – Harvard Health

  https://www.health.harvard.edu/a_to_z/esophagitis-a-to-z

  The main symptoms of esophagitis are: Pain in the chest (behind the breastbone) or throat. The pain can be burning, heavy, or sharp. If acid reflux is the cause of esophagitis, the pain may be worse after meals or when you lie flat. Pain from esophagitis may be constant or may come and go. […] Swallowing problems, including worsening of the chest pain when you swallow or a feeling of food sticking in your chest after you swallow. […] Bleeding, seen as blood in vomit or as darkening of the stools. […] How long symptoms last depends on how easily their cause can be eliminated. Bad cases of reflux or resistant viruses, for example, might require several tries before the right medicine or treatment is found. In most cases, symptoms begin to improve within a few days of starting the right treatment. But it can take weeks for symptoms to go away completely. Esophagitis from an infection may be harder to cure if the immune system is severely weakened. […] Almost all cases of esophagitis can be cured. Some causes, such as acid reflux, may require long-term treatment.

• #2 Management of Gastroesophageal Reflux Disease | AAFP

  https://www.aafp.org/pubs/afp/issues/2003/1001/p1311.html

  The primary treatment goals in patients with gastroesophageal reflux disease are relief of symptoms, prevention of symptom relapse, healing of erosive esophagitis, and prevention of complications of esophagitis. […] In patients with erosive esophagitis identified on endoscopy, a PPI is the initial treatment of choice. […] Many patients self-diagnose and self-treat, and do not seek medical attention for their symptoms, while others have more severe disease, including erosive esophagitis. […] A systematic review of 43 RCTs found faster healing rates in patients with erosive esophagitis who were treated with H2RAs compared with placebo. […] In the treatment of erosive esophagitis, faster healing rates were achieved in patients who received PPI therapy for four to eight weeks (78 percent) than in patients who were given H2RAs (50 percent) or placebo (24 percent) for the same period.

• #2 Eosinophilic Esophagitis – Gastrointestinal Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/gastrointestinal-disorders/esophageal-and-swallowing-disorders/eosinophilic-esophagitis

  The typical patient with eosinophilic esophagitis has dysphagia for solids and a history of atopy. […] The diagnosis of eosinophilic esophagitis is also considered when reflux symptoms fail to respond to acid-suppression therapy. […] Patients who have significant strictures may need careful esophageal dilation using a balloon or bougie; multiple, careful, progressive dilations are done to help prevent esophageal perforation.

• #2 Esophagitis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/174223-overview

  Complications of esophagitis may include the following: Bleeding and stricture formation, Barrett esophagus, Perforation with mediastinitis (rare), Volume depletion and weight loss, Laryngitis, aspiration pneumonitis, and bronchospasm, In infants, failure to thrive and apnea. […] The prognosis is good with rapid diagnosis and proper treatment. Ultimately, prognosis depends on the underlying disease process. […] Complicated esophagitis may lead to esophageal strictures (typically long, smooth, tapered areas of narrowing), malnutrition, and, rarely, perforation or bleeding. […] Severe esophagitis may lead to dysphagia, pain, odynophagia, and malnutrition. Rarely, life-threatening bleeding occurs and may lead to death. […] Recurrence is a frequent problem in patients with reflux. Many patients require maintenance therapy to prevent relapse of symptoms.

• #2 Esophagitis Clinical Presentation: History, Physical Examination

  https://emedicine.medscape.com/article/174223-clinical

  Infectious esophagitis is primarily seen in patients who are immunocompromised. The most common causes of infectious esophagitis are fungal (Candida species) and viral (herpes simplex virus and cytomegalovirus [CMV]). A history of immunosuppression, steroid therapy, recent antibiotic use, or systemic illness supports the diagnosis. Although patients may be asymptomatic, typical symptoms include the following: Onset of difficult or painful swallowing (ie, dysphagia, odynophagia), heartburn, retrosternal discomfort or pain, nausea, vomiting, fever, sepsis, abdominal pain, epigastric pain, hematemesis (occasionally), anorexia, weight loss (depends on chronicity and severity of underlying illness), cough. […] Candida esophagitis is usually manifested clinically by dysphagia and/or odynophagia in a patient with one or more predisposing factors for the condition. Symptoms are variable in severity, ranging from mild difficulty in swallowing to such intense odynophagia that the patient is unable to eat or swallow saliva. Other patients may present with chest pain or gastrointestinal (GI) tract bleeding; occasionally, patients are asymptomatic.

• #2 Esophagitis: Causes, Symptoms & Natural Self-Care – Dr. Axe

  https://draxe.com/health/esophagitis/

  Painful swallowing […] Chest pain during and after eating […] Food that gets stuck in the esophagus […] Heartburn […] Acid reflux […] Nausea or vomiting […] Coughing […] Sore throat […] Hoarse voice. […] Erosive esophagitis causes many of the same symptoms as other types of esophagitis, such as heartburn and difficulty or pain when swallowing. However, when left untreated, erosive esophagitis can lead to blood in vomit or stool. In severe cases it can lead to esophageal strictures, chronic inflammation and ulcers. (29) […] If left untreated, esophagitis can cause serious damage to the esophagus. It can scar the tissue in the food pipe and make it narrower. These strictures can make it very difficult to swallow food. The lining of the esophagus can also be torn when food gets stuck and causes retching, or during an endoscopy if swelling is severe. Finally, untreated esophagitis increases your risk of Barretts esophagus. This is a condition in which cells of the esophagus start to change and increase your risk of esophageal cancer. (59)

• #3 Esophagitis: Types, Symptom, and Risk Factors

  https://www.healthline.com/health/esophagitis

  Symptoms of esophagitis include: trouble swallowing (dysphagia), sore throat, heartburn, pain when you swallow (odynophagia), hoarse voice, acid reflux, chest pain (worse with eating), nausea, vomiting, abdominal pain, decrease in appetite, cough. […] If left untreated, esophagitis may lead to ulcers, scarring, and severe narrowing of the esophagus which can be a medical emergency. Speak with a doctor if you experience any symptoms. […] Esophagitis may take up to 8 weeks to heal with proper treatment. However, chronic esophagitis may require life-long management.

• #3 Gastroesophageal reflux disease | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/stomach-liver-and-gastrointestinal-tract/gastro-oesophageal-reflux-disease-gord/

  Symptoms of GORD can include: […] a sore, inflamed oesophagus (oesophagitis) […] The main symptoms of gastro-oesophageal reflux disease (GORD) are heartburn and acid reflux. […] If you have GORD, you may also experience: […] a sore, inflamed oesophagus (oesophagitis) […] The stomach acid that leaks into the oesophagus in people with GORD can damage the lining of the oesophagus (oesophagitis), which can cause ulcers to form. […] Repeated damage to the oesophagus by stomach acid can also cause it to become scarred and narrowed. […] This is known as oesophageal stricture and it can make swallowing difficult and painful. […] Repeated episodes of GORD can sometimes lead to changes in the cells in the lining of your lower oesophagus. This is known as Barretts oesophagus. […] Its estimated that about 1 in every 10 people with GORD will develop Barretts oesophagus, usually after many years. […] Symptoms of oesophageal cancer include: […] difficulty swallowing […] Speak to your doctor if you experience any swallowing difficulties, or any other unusual or persistent symptoms.

• #3 Eosinophilic Esophagitis (EoE) | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/eosinophilic-esophagitis

  Children experience nausea, regurgitation, vomiting, abdominal pain and a burning feeling similar to acid reflux (heartburn). […] If EoE goes untreated, the esophagus may narrow because of scarring. This is called stricture. […] Older children eat reluctantly and slowly, don’t grow as quickly as expected, develop seemingly irrational aversions to certain foods, and may have trouble sleeping. […] Sometimes EoE is diagnosed after a child or teenager comes to the hospital with food in the esophagus that he or she is unable to cough up. This is called food impaction. […] Some results of the disease, such as scarring of the esophagus, are troubling. […] Based on what we know today, most children do not outgrow eosinophilic esophagitis.

• #3 Esophagitis Clinical Presentation: History, Physical Examination

  https://emedicine.medscape.com/article/174223-clinical

  Patients with human immunodeficiency virus ulcers typically present with acute onset of severe odynophagia, dysphagia, or both. If the ulcers develop at the time of seroconversion, a characteristic maculopapular rash may be seen on the upper half of the body. […] Tuberculous esophagitis occurs primarily in patients with advanced pulmonary or mediastinal tuberculosis or in immunocompromised patients who have disseminated tuberculosis or other mycobacterial diseases.

• #3 EoE – Apfed

  https://apfed.org/about-ead/egids/eoe/

  Symptoms of EoE may vary from one individual to the next and may differ depending on age. Infants and toddlers often refuse their food or have trouble growing properly. School-age children may have recurring abdominal pain, trouble swallowing, or vomiting. Adolescents and adults most often have difficult or painful swallowing. Their esophagus may narrow and cause food to become stuck (impaction), causing a medical emergency. […] Common symptoms include: Reflux that does not respond to medication (acid suppressors) infant, child, adult Difficulty swallowing child, adult Food impactions (food gets stuck in the esophagus) older children, adult Nausea and Vomiting infant, child, adult Failure to thrive (poor growth, malnutrition, or weight loss) and poor appetite infant, child, rarely adult Abdominal or chest pain child, adult Feeding refusal/intolerance or poor appetite infant, child Difficulty sleeping due to chest or abdominal pain, reflux, and/or nausea infant, child, adult

• #3 Esophagitis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK442012/

  Esophagitis refers to inflammation or injury to the esophageal mucosa. The most common symptoms in patients with esophagitis are chest pain, odynophagia, and dysphagia. Patients with EoE may present with food impaction. If the esophagitis is severe and leads to strictures, fistulization, and perforation, patients may present with symptoms related to those entities. […] The most common symptoms and signs are retrosternal chest pain, heartburn, odynophagia or dysphagia. Patients with EoE can present with food impaction and more often seen in young adults or children with some history of asthma, food allergy or atopy. Reflux esophagitis symptoms may include globus sensation, regurgitation and sometimes wheezing or chronic cough. […] Complication of chronic and untreated esophagitis includes bleeding, stricture, Barrett esophagus, perforation, laryngitis, and aspiration pneumonitis.

• #3 Esophagitis and Stricture – ADH – Windsor Center for Digestive Health

  https://windsordigestivehealth.com/conditions-and-diseases/esophagitis-and-stricture/

  Esophagitis is the inflammation of the lining of the esophagus. It presents with noticeable symptoms, such as difficulty swallowing (dysphagia) and severe heartburn. […] Symptoms of esophagitis are noticeable and can be painfully uncomfortable. Patients may experience: Severe heartburn, Difficulty swallowing (dysphagia), Painful swallowing (odynophagia), Regurgitation in the throat and mouth. […] If these symptoms are persistent, you have difficulty swallowing and regurgitation, consult your gastroenterologist as soon as possible. […] If you have a narrowing of the esophagus, you may experience some symptoms. These include: Difficulty swallowing (dysphagia), Burning sensation in the throat, Choking, Feeling as if there is something stuck in your throat. […] If strictures aren’t treated, they can lead to dehydration and malnutrition because your body isn’t getting enough food and nutrients.

• #3 Gastroesophageal Reflux Disease (GERD) – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK554462/

  Gastroesophageal reflux disease (GERD) is a condition where the retrograde flow of the stomach contents into the esophagus or beyond into other regions such as oral cavity, larynx, or the lungs results in inflammation of the esophageal mucosa. […] Esophageal reflux may result in several complications, including esophagitis, upper gastrointestinal bleeding, anemia, peptic ulcer, peptic stricture, dysphagia, gastric cardia cancer, and Barrett esophagus. […] The most common symptoms of GERD are heartburn and acid regurgitation. […] Dysphagia is reported in 30% of patients with reflux esophagitis associated with peptic strictures, Schatzki rings, weak peristalsis, or mucosal inflammation. […] Patients with Grade C and D esophagitis in the Los Angeles classification are characterized by severe reflux. These patients have the lowest healing rate with PPIs. Patients with severe reflux esophagitis typically relapse after treatment and are more likely to develop Barrett esophagus.

• #3 Esophagitis: Symptoms, Causes, Diagnosis, and Treatment

  https://www.verywellhealth.com/esophagitis-overview-and-more-5211946

  With esophagitis, it’s common to experience heartburn, difficulty swallowing, or pain while swallowing. […] Other symptoms may include: sore throat, feeling like something is stuck in your throat, burning sensation in the esophagus, cough, hoarseness, nausea or vomiting, fever. […] Many types of esophagitis respond well to treatment. But esophagitis can have serious consequences if left untreated. […] GERD-related esophagitis has the potential to develop into a condition known as Barrett’s esophagus, in which the lining of the esophagus is damaged by stomach acid. This may increase your risk for esophageal cancer. […] Early diagnosis and treatment are key for the best prognosis, so it’s important to contact a healthcare provider as soon as possible if you suspect you may be experiencing some form of esophagitis.

• #4 Esophagitis: Causes, Symptoms, & Treatments

  https://www.webmd.com/digestive-disorders/esophagitis

  Esophagitis can lead to painful swallowing, acid reflux, chest pain, a feeling that something is stuck in your throat, and more. The side effects happen due to inflammation in your esophagus. […] Symptoms of esophagitis include: Difficult or painful swallowing, Acid reflux, Heartburn, A feeling of something of being stuck in your throat, Chest pain, Nausea, Vomiting. […] If your condition is advanced, you might have bleeding in your esophagus.

• #4 Eosinophilic Esophagitis

  https://www.aaaai.org/conditions-treatments/related-conditions/eosinophilic-esophagitis

  Eosinophilic esophagitis (EoE) is a recognized chronic allergic/immune condition of the esophagus. A person with EoE will have inflammation and increased numbers of eosinophils in the esophagus. The chronic inflammation of EoE leads to symptoms. The symptoms of EoE vary with age. Infants and toddlers may refuse to eat or not grow properly. School-age children often have decreased appetite, recurring abdominal pain, and trouble swallowing or vomiting. Teenagers and adults can have the same symptoms, but often have difficulty swallowing dry or dense, solid foods. The difficulty swallowing occurs because the esophagus is inflamed, and in severe cases, because the esophagus narrows to the point that food gets stuck. Food firmly stuck in the esophagus is called a food impaction, which can be a medical emergency if the food does not pass into the stomach or is not vomited up relatively quickly.

• #4 Esophagitis – infectious Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/diseases-conditions/esophagitis-infectious

  Esophagitis is a term for any inflammation, irritation, or swelling of the esophagus. This is the tube that carries food and liquids from the mouth to the stomach. […] Infectious esophagitis is an infection of the esophagus from viruses, bacteria, fungi, or yeast. This most often occurs in people with a weak immune system. […] Symptoms of infectious esophagitis include: Difficulty swallowing, Painful swallowing, Fever and chills, Yeast infection of the tongue and lining of the mouth (oral thrush), Sores in the mouth or back of the throat (with herpes or CMV). […] In people with a healthy immune system, esophagitis often goes away on its own. People with a weak immune system may take longer to get better.

• #4 Eosinophilic Esophagitis – Digestive Disorders – Merck Manual Consumer Version

  https://www.merckmanuals.com/home/digestive-disorders/esophageal-and-swallowing-disorders/eosinophilic-esophagitis

  Infants and children may refuse to eat and have vomiting, weight loss, and abdominal pain, chest pain, or a combination. […] Adults who have a stricture (usually those who have had esophagitis for a long time) often have difficulty swallowing (dysphagia) and may have food lodged in their esophagus (called esophageal food impaction). People may have symptoms similar to those of gastroesophageal reflux disease (GERD), particularly heartburn (a burning pain behind the breastbone). […] Eosinophilic esophagitis may be caused by an allergic reaction to certain foods in people who have genetic risk factors. The allergic reaction causes inflammation that irritates the esophagus. If not treated, the inflammation eventually leads to chronic narrowing (stricture) of the esophagus.

• #4 Esophagitis | UM Health-Sparrow

  https://www.uofmhealthsparrow.org/departments-conditions/conditions/esophagitis

  Esophagitis can cause painful, difficult swallowing. […] Common symptoms of esophagitis include trouble swallowing, painful swallowing, swallowed food becoming stuck in the esophagus, burning pain in the chest called heartburn, and stomach acid that backs up into the esophagus. […] One common symptom of eosinophilic esophagitis is food getting stuck in the esophagus after swallowing. This is called food impaction. Another common symptom is trouble swallowing, also called dysphagia. […] Without treatment, esophagitis can damage this lining. The esophagus may start to have trouble moving food and liquid from the mouth to the stomach. Esophagitis also can lead to other serious health issues. These include scarring or narrowing of the esophagus, unhealthy weight loss, and dehydration. […] Without treatment, esophagitis can lead to changes in the structure of the esophagus. Complications can include scarring or narrowing of the esophagus, known as a stricture.

• #4 Gastroesophageal Reflux Disease (GERD) – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK554462/

  Approximately 10% of patients with reflux develop Barrett esophagus, a precursor for adenocarcinoma of the esophagus. […] Complications associated with GERD are listed below. […] Barrett esophagus occurs in 5% to 15% of patients with reflux esophagitis. This complication is more likely to occur in White male patients with severe reflux esophagitis who have had the symptoms for a longer duration and are older than 50.

• #5 Esophagitis: Symptoms & Treatment

  https://www.medicinenet.com/esophagitis/article.htm

  Esophagitis or inflamed esophagus symptoms include hoarseness, mouth sores, and bad breath. […] Esophagitis symptoms may include the following: Bad breath (halitosis), A feeling of food getting stuck while swallowing, Difficult and/or painful swallowing, Pain in the middle of the chest, often radiating to the back, is usually associated with swallowing or occurring soon after a meal, An unpleasant taste in the mouth, Indigestion, Heartburn, Acid reflux, Sore throat, Hoarseness, Cough, Mouth sores, Nausea, Vomiting, Abdominal pain or indigestion. […] The prognosis for esophagitis often depends on the underlying cause. Esophagitis caused by infection or inflammation is generally treatable with medications, diet or behavioral changes, and in some cases, surgery. Most people can recover fully, while some have chronic inflammation that is managed with long-term medical treatment. Esophagitis caused by reflux, while often manageable, can recur frequently. Many people with reflux require medication or other treatments to prevent relapses.

• #5 Eosinophilic Esophagitis Symptoms | Northwestern Medicine

  https://www.nm.org/conditions-and-care-areas/gastroenterology/eosinophilic-esophagitis/symptoms

  Symptoms of eosinophilic esophagitis can vary depending on the severity of the inflammation. Symptoms include: Dysphagia (difficulty swallowing) […] Chest or upper abdominal pain […] Food stuck in the esophagus […] Heartburn that doesnt respond to medication […] Regurgitation (the return of partially digested food from the stomach to the mouth) […] In children, vomiting, poor weight gain or failure to thrive. If food becomes impacted (stuck) in your esophagus, please contact your physician immediately.

• #6 Esophagitis – Symptoms, Causes, Treatments

  https://resources.healthgrades.com/right-care/digestive-health/esophagitis

  Esophagitis is inflammation of the esophagus, which can result in symptoms such as hoarseness, difficulty swallowing, and heartburn. […] The signs and symptoms of esophagitis can occur every day or only after eating certain foods. Some people with esophagitis have mild symptoms such as hoarseness, while others may have severe burning and difficulty swallowing. […] The symptoms of esophagitis result from irritation or infection of the esophagus and can vary in intensity among individuals. […] You may experience esophagitis symptoms daily or just once in a while. At times any of these symptoms can be severe: Burning feeling in the throat or chest, Difficulty swallowing, Hoarse voice. […] You may experience other symptoms with esophagitis. Examples include: Cold sores, Fever and chills, Joint pain, White patches in your mouth and on your tongue.

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