Materiały źródłowe

• #1 Esophagitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/esophagitis/symptoms-causes/syc-20361224

  Esophagitis can cause painful, difficult swallowing. It also can lead to chest pain. Various things can cause esophagitis. Some common causes include stomach acids backing up into the esophagus, infection, medicines taken by mouth and allergies. […] Healthcare professionals tend to label esophagitis by the condition that causes it. Sometimes, esophagitis may have more than one cause. Some of the most common types include the following: […] A valve called the lower esophageal sphincter usually keeps stomach acid out of the esophagus. But sometimes this valve doesn’t close properly. Or it opens when it shouldn’t. In some people, the upper part of the stomach bulges through the large muscle that separates the stomach and the chest. This is known as a hiatal hernia. It also can cause stomach acid to back up into the esophagus.

• #1 Esophagitis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/174223-overview

  The most common cause of esophagitis is gastroesophageal reflux disease (GERD). […] Other important, but less common, types of esophagitis include infectious esophagitis (in patients who are immunocompromised), radiation esophagitis, and esophagitis from direct erosive effects of ingested medication or corrosive agents. […] Eosinophilic esophagitis has also emerged as an important cause of esophagitis in both children and adults. […] The various types of esophagitis are associated with differing causative conditions and risk factors. […] Factors or conditions that may increase the risk of reflux esophagitis include pregnancy, obesity, scleroderma, smoking, alcohol, coffee, chocolate, fatty or spicy foods, and certain medications. […] Infectious agents known to cause esophagitis include Candida species, herpes simplex virus (HSV), cytomegalovirus (CMV), and varicella-zoster virus (VZV).

• #1 Reflux Esophagitis Pathology: Definition, Epidemiology, Etiology

  https://emedicine.medscape.com/article/1610393-overview

  The acidic nature of the refluxed gastric content is predominantly responsible for esophageal mucosal damage and the subsequent development of reflux esophagitis. The frequency of acid reflux correlates more with erosive reflux esophagitis than with NERD. […] The presence of bile in reflux contents is increasingly being thought to contribute to reflux disease in a subset of cases, as observed in patients on proton pump inhibitor (PPI) therapy, the medical treatment of choice for GERD. […] Poor or abnormal LES function is the most common cause of GERD. […] Poor esophageal clearance due to motility disorders is common in older adults or in patients with achalasia, stroke, or collagen vascular disease such as scleroderma. […] Delayed gastric emptying can lead to spillage of the retained gastric contents of a full stomach back into the esophagus, thereby causing reflux disease.

• #1 Esophagitis | UM Health-Sparrow

  https://www.uofmhealthsparrow.org/departments-conditions/conditions/esophagitis

  Gastroesophageal reflux disease (GERD) is a condition in which this backflow of acid is a frequent or ongoing problem. GERD can lead to ongoing swelling and tissue damage in the esophagus. […] Eosinophils (e-o-SIN-o-fils) are white blood cells that play a key role in allergic reactions. Eosinophilic esophagitis can happen if lots of these white blood cells build up in the esophagus. This most likely happens in response to a substance that causes an allergy, acid reflux or both. […] Certain foods may trigger this type of esophagitis, including: Milk, Eggs, Wheat, Soy, Peanuts, Seafood. […] Lymphocytic esophagitis (LE) isn’t a common condition of the esophagus. With LE, a higher than typical number of white blood cells called lymphocytes build up in the lining of the esophagus. LE may be related to eosinophilic esophagitis or to GERD.

• #1 Eosinophilic Esophagitis

  https://www.aaaai.org/conditions-treatments/related-conditions/eosinophilic-esophagitis

  Eosinophilic esophagitis (EoE) is a recognized chronic allergic/immune condition of the esophagus. In EoE, large numbers of white blood cells called eosinophils are found in the inner lining of the esophagus. Eosinophils can release substances into surrounding tissues that cause inflammation. A person with EoE will have inflammation and increased numbers of eosinophils in the esophagus. […] The majority of patients with EoE are atopic. […] Immune reactions to foods are the main cause of EoE in most patients. […] Foods such as dairy products, wheat, egg, and soy are recognized as the most common triggers for EoE. […] Once the causative food(s) is (are) identified and removed from a persons diet, esophageal inflammation and symptoms generally improve in a few weeks. […] Eliminating the major food allergens from the diet is considered an acceptable treatment of EoE.

• #1 Etiology of Eosinophilic Esophagitis

  https://www.aap.org/en/patient-care/eosinophilic-esophagitis/etiology/?srsltid=AfmBOoodTLZzVxf_YxtBcC9GWSWZmsFsJHXY4aIOkBMwZeOWGF55Nl_G

  Population studies show a steady rise in the incidence (6.6 per 100,000 person-years) and prevalence (34 per 100,000) of Eosinophilic Esophagitis (EoE) in children. […] The etiology of EoE is not completely understood, but like other atopic diseases, it appears to result from an interplay between genetics and environment. […] The marked increase in the diagnosis of EoE along with data from twin studies indicate that environmental factors likely play a large role in the etiology of EoE. […] Environmental factors that are reliably associated with EoE include: Food allergens Milk is the most common food trigger of EoE (followed by wheat, egg, and soy) […] Antibiotics in infancy Similar to observational studies for other atopic conditions, antibiotic use in infancy is correlated with a higher risk of EoE, but causality has not been established.

• #1 A Quick Summary of Esophagitis – Gastroenterology Health Partners

  https://gastrohealthpartners.com/a-quick-summary-of-esophagitis/

  Esophagitis can be caused by various things. One of the most common causes is reflux. Reflux occurs when stomach acid backflows into the esophagus. A condition called GERD (gastrointestinal reflux disease) causes this to happen recurrently, and is a likely culprit for esophagitis in many cases. GERD can cause chronic inflammation over time. Infection can also cause esophagitis in rarer cases, mostly in people with diminished immune system function. […] Oral medications can also cause inflammation in the esophagus if they are in contact with the esophagus for too long. This can happen if you take oral medications without enough liquid, oral medications that are irregularly shaped or large, if you take medications immediately before sleeping, or if you take them lying down. These medications include pain relievers like ibuprofen and aspirin, and some antibiotics.

• #1 Esophagitis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK442012/

  Pill induced esophagitis is most commonly associated with oral bisphosphonates like alendronate, some antibiotics like tetracycline, doxycycline, and clindamycin. NSAIDs, aspirin, ferrous sulfate, potassium chloride, and mexiletine has also been reported as a cause of pill-induced esophagitis. […] Eosinophilic esophagitis (EoE) is now thought to be a chronic immune antigen-related esophageal disease with almost similar symptoms of esophagitis but histologically have squamous mucosal inflammation caused by predominant eosinophilic infiltration. […] Radiation-induced esophagitis is associated with radiotherapy related toxicity and can present as both in acute and chronic forms.

• #1 Pill esophagitis – UpToDate

  https://www.uptodate.com/contents/pill-esophagitis

  Pill esophagitis […] Medications can induce esophageal abnormalities via both causing direct esophageal mucosal injury and by systemic effects. Potential systemic effects include gastroesophageal reflux and medication-induced infectious complications. […] More than 100 different medications have been reported to cause pill esophagitis. Frequently prescribed medications associated with pill esophagitis include the following: Antibiotics – Antibiotics account for approximately 50 percent of reported cases of pill esophagitis and the most frequent etiology of pill esophagitis in younger adults. Tetracyclines are the most common antibiotic class implicated, but penicillins, trimethoprim-sulfamethoxazole, clindamycin, lincomycin, spiramycin, erythromycin, rifampicin, sulfamethoxypyridazine, tinidazole, zalcitabine, zidovudine, and azithromycin have all been associated with medication-induced esophagitis. Esophagitis is due to the direct irritant effect of the medications on the mucosa.

• #1 Esophagitis: What It Is, Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/10138-esophagitis

  Also called pill esophagitis, this type occurs when frequently used medications erode the mucous lining of your esophagus. […] Infections in your esophagus are uncommon unless you have a weaker immune system and are prone to more frequent and more severe infections in general. […] Eosinophilic esophagitis is a type of immune hypersensitivity reaction (an overreaction of your immune system). […] Besides eosinophilic esophagitis, certain other autoimmune diseases can cause esophagitis as a side effect. […] Radiation therapy targeting your esophagus, chest or throat may cause radiation mucositis, inflammation of the mucosa in your esophagus. […] Esophagitis is treatable, but severe esophagitis that goes untreated can lead to serious complications, such as: Ulcers. Esophageal stricture. Intestinal metaplasia. […] If you’re confident that the injury that caused it has stopped, your esophagitis may be able to heal on its own after several weeks. […] GERD is the most common cause of esophagitis, but not the only cause. And GERD doesn’t always cause esophagitis in everyone.

• #1 Esophagitis | UM Health-Sparrow

  https://www.uofmhealthsparrow.org/departments-conditions/conditions/esophagitis

  Also called drug-induced esophagitis, this type happens when some medicines taken by mouth cause tissue damage in the esophagus. The damage happens if the medicines stay in contact with the lining of the esophagus for too long. […] An infection in tissues of the esophagus may cause esophagitis. The infection could be due to bacteria, viruses or funguses. Infectious esophagitis is fairly rare. It happens most often in people with weakened immune systems, such as people with HIV/AIDS or cancer. […] A fungus usually present in the mouth called Candida albicans is a common cause of infectious esophagitis. This type of fungal infection often is linked with a weakened immune system, diabetes, cancer, or use of steroid or antibiotic medicines.

• #1 Esophagitis – infectious Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/diseases-conditions/esophagitis-infectious

  Esophagitis is a term for any inflammation, irritation, or swelling of the esophagus. This is the tube that carries food and liquids from the mouth to the stomach. […] Infectious esophagitis is an infection of the esophagus from viruses, bacteria, fungi, or yeast. This most often occurs in people with a weak immune system. […] Infectious esophagitis is rare. It often occurs in people with weak immune systems. People who have strong immune systems don’t usually develop the infection. […] Common causes of a weakened immune system include: HIV/AIDS, Chemotherapy, Diabetes, Leukemia or lymphoma, Medicines that suppress the immune system, such as ones given after organ or bone marrow transplant, Other conditions that suppress or weaken your immune system. […] Organisms (germs) that cause esophagitis include fungi, yeast, and viruses. Common organisms include: Candida albicans and other Candida species, Cytomegalovirus (CMV), Herpes simplex virus (HSV), Human papillomavirus (HPV), Tuberculosis bacteria (Mycobacterium tuberculosis) — not common.

• #1 Esophagitis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/174223-overview

  Major predisposing factors for Candida esophagitis include antibiotic use, radiation therapy or chemotherapy, hematologic malignancies, and acquired immunodeficiency syndrome (AIDS). […] Systemic illnesses that can result in esophagitis include skin disorders, eosinophilic esophagitis, graft versus host disease, inflammatory bowel disease, and metastatic cancer. […] Therapeutic interventions that can cause esophagitis include medications, radiation esophagitis, and sclerosant and band ligation therapy for varices. […] Pill esophagitis is thought to be secondary to chemical irritation of the esophageal mucosa by certain medications.

• #1 Esophagitis and its causes: Who is “guilty” when acid is found “not guilty”?

  https://www.wjgnet.com/1007-9327/full/v23/i17/3011.htm

  The damage of esophageal mucosa induced by commonly-used drugs is certainly underestimated. In fact many compounds are potentially aggressive to the esophageal wall, either by a direct toxic activity on the mucosa or by the production of caustic acidic or alkaline solutions; however the low awareness of these effects usually allows continuous assumption of the medications, with consequent more severe complications. […] Infectious diseases with esophageal involvement represent a quite uncommon condition in immunocompetent subjects. Fungi, virus and bacteria can cause esophageal damage in patients with immunodeficiency (i.e., HIV infection, history of malignancies, prolonged use of immunosuppressive drugs or steroids). […] Corrosive esophagitis occurs from voluntary or accidental ingestion of alkaline liquids and, less frequently, acidic substances. […] Many chemotherapeutic regimens may determine the occurrence of esophageal damage, usually as a consequence of a severe oropharyngeal mucositis.

• #1 Esophagitis: Causes, symptoms, and treatments

  https://www.medicalnewstoday.com/articles/9274

  Esophagitis is inflammation of the esophagus. Various health conditions can cause esophagitis, and it can lead to pain, nausea, and other symptoms. […] Several conditions can cause esophagitis. Sometimes, the condition may be caused by more than one factor. […] This is the most common cause known as reflux esophagitis. GERD can irritate the esophagus, leading to esophagitis. […] Certain allergies can cause eosinophilic esophagitis, triggered by an allergic reaction. […] Some medications can cause esophagitis, this is known as drug-induced esophagitis. […] Infectious esophagitis can occur in people who have weakened immune systems. […] Other causes of esophagitis include alcohol abuse, radiation therapy, nasogastric tubes, and chemical injury from ingested alkaline or acid solutions.

• #1 Esophagitis: Types, Symptom, and Risk Factors

  https://www.healthline.com/health/esophagitis

  Inflammation or irritation of the esophagus is known as esophagitis. It may be caused by acid reflux, bacterial or viral infections, or certain medications. […] Eosinophilic esophagitis is caused by having too many eosinophils in the esophagus. This happens when your body responds to an allergen. […] Certain medications may create an acidic environment in your stomach and cause esophageal inflammation. […] Infectious esophagitis is rare. Its most commonly caused by: Candida, which is a type of fungus; herpes simplex virus, which is a viral infection; cytomegalovirus, which is a type of herpes virus; human papillomavirus (HPV), which is a sexually transmitted infection (STI). […] Radiation esophagitis occurs as a complication of radiation therapy for cancer. […] Risk factors for developing esophagitis may include: weakened immune system due to certain conditions, such as HIV or AIDS, diabetes, or leukemia; hiatal hernia; chemotherapy; radiation therapy of the chest; surgery in the chest area; medications to prevent organ transplant rejection; immunosuppressive medications used to treat autoimmune diseases; aspirin and anti-inflammatory medications; chronic vomiting; obesity; alcohol and cigarette use; a family history of allergies or esophagitis.

• #1 Esophagitis: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/001153.htm

  Esophagitis is often caused by stomach fluid that flows back into the food pipe. The fluid contains acid, which irritates the esophageal lining. This problem is called gastroesophageal reflux (GERD). An autoimmune and allergic disorder called eosinophilic esophagitis also causes this condition. […] The following increase your risk for esophagitis: Alcohol use, Cigarette smoking, Surgery or radiation to the chest (for example, treatment for lung cancer), Taking certain medicines such as alendronate, doxycycline, ibandronate, risedronate, tetracycline, potassium tablets, and vitamin C, without drinking plenty of water, Vomiting, Lying down after eating a large meal, Obesity. […] People who have a weakened immune system may develop infections. Infections may lead to swelling of the food pipe. Infection may be due to: Fungi or yeast (most often Candida), Viruses, such as herpes or cytomegalovirus.

• #1 Esophagitis | Beacon Health System

  https://www.beaconhealthsystem.org/library/diseases-and-conditions/esophagitis?content_id=CON-20312402

  Eosinophilic esophagitis can happen if lots of these white blood cells build up in the esophagus. This most likely happens in response to a substance that causes an allergy, acid reflux or both. […] An infection in tissues of the esophagus may cause esophagitis. The infection could be due to bacteria, viruses or funguses. Infectious esophagitis is fairly rare. […] Risk factors for esophagitis vary depending on the cause of the condition. […] Risk factors for infectious esophagitis often relate to medicines such as steroids or antibiotics. People with diabetes also have a higher risk of esophagitis caused by a fungal candida infection in particular. […] Without treatment, esophagitis can lead to changes in the structure of the esophagus. Complications can include scarring or narrowing of the esophagus, known as a stricture.

• #1 Eosinophilic Esophagitis | Symptoms & Treatment | ACAAI Public Website

  https://acaai.org/allergies/allergic-conditions/eosinophilic-esophagitis/

  Eosinophilic Esophagitis (known as EoE) is a disorder of the esophagus, the tube that connects your mouth to your stomach. EoE is increasingly recognized as a major cause of swallowing difficulties in children and adults. […] A chronic immune system disease, EoE can be triggered by a food allergy, acid reflux – when acid backs up from your stomach into your esophagus – or an airborne (seasonal) allergy. […] Experts believe both genetic and environmental factors play a role in the development of EoE. About half of people with EoE also have seasonal allergies or asthma. […] The foods that most commonly cause an allergic reaction leading to EoE include milk, eggs, wheat, soy, peanuts or tree nuts and fish or shellfish. […] You may have a combination of allergies that increase the risk of EoE. For example, although it is rare for pollen allergies alone to cause EoE, about one in four people who have food allergy-induced EoE notice a seasonal variation in their symptoms.

• #1 Eosinophilic Esophagitis: What it Is, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/14321-eosinophilic-esophagitis

  Eosinophilic esophagitis is an inflammation of the esophagus caused by an overabundance of certain white blood cells. Food allergies are thought to be one cause of the condition. […] The disease happens when your immune system reacts to allergens in your esophagus, filling it with inflammatory cells, including eosinophils and cytokines. Allergens can be environmental or food triggers. […] A risk factor is something that increases the chance you’ll have a disease. Many people with eosinophilic esophagitis also have: Asthma, Allergic rhinitis, Atopic dermatitis, Eczema, Food allergies. […] Damage to your esophagus from eosinophilic esophagitis may cause the following complications: Esophageal perforation (rupture), Esophageal strictures.

• #1 Eosinophilic Esophagitis Causes

  https://www.neocate.com/food-allergy-resources/food-allergy-conditions/eosinophilic-esophagitis/causes/?srsltid=AfmBOoq9-7xclMA6C0eNoi9b2aYinqTOq6Q8DvMVwP6vPB3TIBSbMv08

  Like many food allergies and related disorders, doctors arent sure of the exact cause of EoE. […] Most often, EoE is attributed to certain food(s) which trigger adverse immune responses. The most common food allergen in EoE is milk protein, and many patients with EoE are allergic to two or more foods. […] In EoE, food allergens can cause large numbers of eosinophils to move into the esophagus, where they do not belong. The presence of too many eosinophils causes inflammation of the esophagus, or esophagitis.

• #1 What is Eosinophilic Esophagitis (EoE)? Including Symptoms & Causes

  https://www.eoecare.com/what-is-eoe

  Eosinophilic esophagitis can be hard to say, and it can be even harder to live with. […] EoE can run in the family, but its exact cause is uncertain. Researchers think EoE is triggered by food allergens or other substances in the environment, such as dust, mites, pollen, or molds. Their presence alerts the immune system in your esophagus and it responds with swelling and inflammation. […] The underlying cause of EoE is chronic inflammation, which is why symptoms don’t go away. People with EoE have a large number of cells called eosinophils in their esophagus. Normally, eosinophils are not found there. Eosinophils and other triggers are what cause chronic inflammation in the esophagus. This chronic inflammation can do damage to the structure of your esophagus, causing swelling, scarring, and narrowing (called strictures). […] The damage from chronic inflammation can make your EoE symptoms get worse. The longer this inflammation goes untreated, the more damage it can do to your esophagus over time.

• #1

  https://www.wyndly.com/blogs/learn/eosinophilic-esophagitis?srsltid=AfmBOoqZdBpxrggwUwqaNace__p6qLcikP1ZuZOtRZF-8po5OXfQ_Dxf

  Eosinophilic Esophagitis (EoE) is believed to be caused by a combination of factors. The immune system’s overreaction to allergens and certain genetic factors play significant roles in the development of this condition. […] The immune system’s overreaction to allergens is a key factor in the development of EoE. When an allergen is detected, the body produces Immunoglobulin E (IgE), which triggers an immune response. This response can lead to the accumulation of eosinophils in the esophagus. Allergens that may trigger this response include certain foods, environmental allergens like dust mites, and pollen. Oral Allergy Syndrome (OAS), a condition where certain food proteins cross-react with pollen allergens, could also be a potential trigger. […] EoE is also influenced by genetic factors. Some individuals have a family history of EoE, suggesting a hereditary predisposition. Moreover, certain genes have been associated with EoE, indicating a genetic component to the disease. These genes are involved in the regulation of the immune response, particularly the function and accumulation of eosinophils. Research is ongoing to better understand the interplay of these factors in EoE.

• #1 Esophagitis | Concise Medical Knowledge

  https://www.lecturio.com/concepts/esophagitis/

  Esophagitis is the inflammation Inflammation Inflammation is a complex set of responses to infection and injury involving leukocytes as the principal cellular mediators in the body’s defense against pathogenic organisms. The major types of esophagitis are medication-induced, infectious, eosinophilic, corrosive, and acid reflux. Treatment for esophagitis depends on the underlying etiology and includes dietary changes, avoidance of offending agents, antibiotic therapy, or proton pump Pump ACES and RUSH: Resuscitation Ultrasound Protocols inhibitor use. […] Major etiologies: Medication-induced/pill-induced esophagitis, Infectious esophagitis, Eosinophilic esophagitis, Corrosive esophagitis, Reflux esophagitis. […] Prolonged, direct contact between the medication(s) and the mucosa causes irritation, erosions Erosions Corneal Abrasions, Erosion, and Ulcers, and ulcerations.

• #1 Esophagitis Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/diseases-conditions/esophagitis

  Esophagitis is often caused by stomach fluid that flows back into the food pipe. The fluid contains acid, which irritates the esophageal lining. This problem is called gastroesophageal reflux (GERD). An autoimmune and allergic disorder called eosinophilic esophagitis also causes this condition. […] People who have a weakened immune system may develop infections. Infections may lead to swelling of the food pipe. Infection may be due to: […] Most of the time, the disorders that cause swelling and inflammation of the food pipe, respond to treatment. […] If not treated, this condition may cause severe discomfort. Scarring (stricture) of the food pipe may develop. This can cause swallowing problems. […] A condition called Barrett esophagus (BE) can develop after years of GERD. Rarely, BE may lead to cancer of the food pipe.

• #1 Esophagitis: Causes, Symptoms & Natural Self-Care – Dr. Axe

  https://draxe.com/health/esophagitis/

  Esophagitis is inflammation of the esophagus (the muscular tube connecting your mouth to your stomach). It causes pain or difficulty swallowing food and pills, and can make eating very uncomfortable. When it goes untreated, esophagitis can lead to changes in the esophagus that can make it hard to swallow food without choking. (1) […] There are many potential causes of esophagitis. […] There are several different types, each with its own cause and treatment. […] Reflux esophagitis is typically treated with OTC or prescription antacids, proton pump inhibitors (PPIs), H-2-receptor blockers, or prokinetics. […] Eosinophilic esophagitis risk factors include food allergies and a family history of the condition, as well as male gender, white race and having other allergic issues (asthma, allergic rhinitis, or eczema).

• #1 Esophagitis: Causes, Symptoms & Natural Self-Care – Dr. Axe

  https://draxe.com/health/esophagitis/

  Drug-induced esophagitis treatment mostly involves taking replacement/alternative medications to reduce irritation. […] Infectious esophagitis treatment requires treating the bacterium, virus, fungus or parasite that is causing the infection. […] When acid from the stomach enters the esophagus because of GERD, it can eat away at the lining of the esophagus and cause an ulcer. […] Other causes include smoking, too much alcohol, or infection with Helicobacter pylori, HIV, Candida, the herpes simplex virus or cytomegalovirus. […] If left untreated, esophagitis can cause serious damage to the esophagus. It can scar the tissue in the food pipe and make it narrower. […] These strictures can make it very difficult to swallow food. […] The lining of the esophagus can also be torn when food gets stuck and causes retching, or during an endoscopy if swelling is severe. […] Finally, untreated esophagitis increases your risk of Barretts esophagus. This is a condition in which cells of the esophagus start to change and increase your risk of esophageal cancer. (59)

• #1 Esophagitis – Causes, Symptoms, Risk Factors, Diagnosis, And Treatment | Dr. Samrat Jankar

  https://www.drsamratjankar.com/blogs/esophagitis-causes-symptoms-risk-factors-diagnosis-and-treatment/

  Esophagitis can be caused by a variety of factors, including: […] If you have GERD (gastroesophageal reflux disease), which occurs when stomach acid frequently leaks into your esophagus […] If you experience persistent vomiting […] If you suffer from the autoimmune disease scleroderma that hardens and tightens the skin […] If you are allergic to certain foods. […] The eminent surgical gastroenterologist in Pune, Dr. Samrat Jankar, adds that other causes of esophagitis include ingestion of acidic or alkaline solutions and (NG) nasogastric tube insertion. […] Acidic or alkaline solutions cause chemical injury to your esophagus. […] Treatment is entirely determined by the cause of the inflammation: […] Esophagitis can have a negative impact on the quality of your life. If not treated in time, it can progress into Barretts esophagus and make you more susceptible to esophageal cancer.

• #1 Is Erosive Esophagitis Serious? Causes, Symptoms & Treatment

  https://www.medicinenet.com/how_serious_is_erosive_esophagitis/article.htm

  Erosive esophagitis can be cured especially when detected and treated early. […] Erosive esophagitis can cause serious consequences if left untreated. The complications include esophageal scarring or stricture formation. […] What causes esophagitis? Depending on its cause, esophagitis can be of five main types: Reflux esophagitis, caused by the reflux of stomach contents into the esophagus. This leads to injury to the lining of the esophagus, resulting in erosions and inflammation. […] Infectious esophagitis occurs due to an infection of the esophagus, leading to its inflammation. […] Eosinophilic esophagitis (EoE) may occur due to a chronic accumulation of immune cells called eosinophils in the esophagus. […] Pill-induced or drug-induced esophagitis is caused in response to certain medications. […] Radiation-induced esophagitis affects people who undergo radiotherapy. The radiation can cause esophagitis by damaging the esophageal lining, leading to inflammation.

• #1

  https://aminoco.com/blogs/health/esophagitis-symptoms-causes-treatments?srsltid=AfmBOoooueYyhhVs4svWv5AXKFF2T97nh8c8waJYTtnKjCvdTMnygCgv

  Esophagitis is defined as inflammation, irritation, or swelling of that tube. It can be caused by viral or bacterial infections, medications, and acid reflux, the backup of stomach acids and other contents returning to the esophagus. […] Chronic esophagitis can cause the esophagus to narrow and result in tissue damage if you do not get treatment. The possibility of esophageal cancer is greater if the cells lining the esophagus have changed due to chronic acid exposure. […] Avoiding identified triggers lowers the risk of future bouts of esophagitis. Potential long-term health complications of untreated esophagitis are Barretts esophagus, damage to the lining of the esophagus leading to a precancerous change in the tissue, narrowing of the esophagus that can cause obstruction and problems swallowing, and holes or ulcers in the esophagus known as esophageal perforations.

• #2 Esophagitis: Causes, symptoms, and treatments

  https://www.medicalnewstoday.com/articles/9274

  Esophagitis is inflammation of the esophagus. Various health conditions can cause esophagitis, and it can lead to pain, nausea, and other symptoms. […] Several conditions can cause esophagitis. Sometimes, the condition may be caused by more than one factor. […] This is the most common cause known as reflux esophagitis. GERD can irritate the esophagus, leading to esophagitis. […] Certain allergies can cause eosinophilic esophagitis, triggered by an allergic reaction. […] Some medications can cause esophagitis, this is known as drug-induced esophagitis. […] Infectious esophagitis can occur in people who have weakened immune systems. […] Other causes of esophagitis include alcohol abuse, radiation therapy, nasogastric tubes, and chemical injury from ingested alkaline or acid solutions.

• #2 Esophagitis: What It Is, Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/10138-esophagitis

  Inflamed esophageal lining caused by acid that escapes your stomach into your esophagus. Acid escaping your stomach into your esophagus can cause esophagitis. […] Chronic acid reflux (GERD) is a common cause of esophagitis. Other types of esophagitis are relatively rare. Esophageal infections are uncommon, except in people who have compromised immune systems. […] Your esophagus tissues might become inflamed if your immune system has been activated to fight an infection, if you’re having an allergic reaction or if something corrosive has injured the tissues. […] Causes include: Acid reflux. Medications. Infections. Allergies. Radiation. Autoimmune disease. […] Different causes make up different subtypes of esophagitis. […] The most common type of esophagitis occurs when acids and digestive agents escape your stomach and reflux into your esophagus, irritating and eroding the mucous lining (mucosa). This may happen if you have frequent acid reflux or if you vomit frequently.

• #2 Esophagitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/esophagitis/symptoms-causes/syc-20361224

  Gastroesophageal reflux disease (GERD) is a condition in which this backflow of acid is a frequent or ongoing problem. GERD can lead to ongoing swelling and tissue damage in the esophagus. […] Eosinophilic esophagitis can happen if lots of these white blood cells build up in the esophagus. This most likely happens in response to a substance that causes an allergy, acid reflux or both. […] Infectious esophagitis is fairly rare. It happens most often in people with weakened immune systems, such as people with HIV/AIDS or cancer. […] A fungus usually present in the mouth called Candida albicans is a common cause of infectious esophagitis.

• #2 Reflux Esophagitis Pathology: Definition, Epidemiology, Etiology

  https://emedicine.medscape.com/article/1610393-overview

  Obesity is an important risk factor for the development of GERD. […] The protective role of Helicobacter pylori infection in the development of GERD remains controversial. […] A report by Yang et al alluded to the role of microbiome alterations in the pathogenesis of reflux esophagitis and subsequent progression to Barrett esophagus.

• #2 Esophagitis | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/esophagitis

  Esophagitis is inflammation of the lining of the esophagus, the muscular tube that connects the pharynx (throat) to the stomach. In children, it is usually the result of gastroesophageal reflux disease (GERD), eosinophilic esophagitis, infection, or ingestion of corrosive substances (such as cleaning products or battery acid). […] Esophagitis is inflammation that typically occurs when your child’s esophagus is exposed to irritating substances, whether that means corrosive products, food allergens or their own stomach acid. Your child is more likely to develop esophagitis if they have: […] GERD, which involves the chronic regurgitation of stomach acid […] Eosinophilic esophagitis, an allergic reaction that can cause inflammation […] Food allergies […] Ingested corrosive substances, such as certain household cleaners and batteries […] Ingested certain medications, including inhaled or swallowed steroids, doxycycline, tetracycline, iron supplements or nonsteroidal anti-inflammatory drugs […] Compromised immunity […] Infections, most commonly those involving Candida (yeast) or herpes simplex virus.

• #2 Esophagitis | UM Health-Sparrow

  https://www.uofmhealthsparrow.org/departments-conditions/conditions/esophagitis

  Also called drug-induced esophagitis, this type happens when some medicines taken by mouth cause tissue damage in the esophagus. The damage happens if the medicines stay in contact with the lining of the esophagus for too long. […] An infection in tissues of the esophagus may cause esophagitis. The infection could be due to bacteria, viruses or funguses. Infectious esophagitis is fairly rare. It happens most often in people with weakened immune systems, such as people with HIV/AIDS or cancer. […] A fungus usually present in the mouth called Candida albicans is a common cause of infectious esophagitis. This type of fungal infection often is linked with a weakened immune system, diabetes, cancer, or use of steroid or antibiotic medicines.

• #2 Pill esophagitis – UpToDate

  https://www.uptodate.com/contents/pill-esophagitis

  Pill esophagitis […] Medications can induce esophageal abnormalities via both causing direct esophageal mucosal injury and by systemic effects. Potential systemic effects include gastroesophageal reflux and medication-induced infectious complications. […] More than 100 different medications have been reported to cause pill esophagitis. Frequently prescribed medications associated with pill esophagitis include the following: Antibiotics – Antibiotics account for approximately 50 percent of reported cases of pill esophagitis and the most frequent etiology of pill esophagitis in younger adults. Tetracyclines are the most common antibiotic class implicated, but penicillins, trimethoprim-sulfamethoxazole, clindamycin, lincomycin, spiramycin, erythromycin, rifampicin, sulfamethoxypyridazine, tinidazole, zalcitabine, zidovudine, and azithromycin have all been associated with medication-induced esophagitis. Esophagitis is due to the direct irritant effect of the medications on the mucosa.

• #2 Esophagitis: Types, Symptom, and Risk Factors

  https://www.healthline.com/health/esophagitis

  Inflammation or irritation of the esophagus is known as esophagitis. It may be caused by acid reflux, bacterial or viral infections, or certain medications. […] Eosinophilic esophagitis is caused by having too many eosinophils in the esophagus. This happens when your body responds to an allergen. […] Certain medications may create an acidic environment in your stomach and cause esophageal inflammation. […] Infectious esophagitis is rare. Its most commonly caused by: Candida, which is a type of fungus; herpes simplex virus, which is a viral infection; cytomegalovirus, which is a type of herpes virus; human papillomavirus (HPV), which is a sexually transmitted infection (STI). […] Radiation esophagitis occurs as a complication of radiation therapy for cancer. […] Risk factors for developing esophagitis may include: weakened immune system due to certain conditions, such as HIV or AIDS, diabetes, or leukemia; hiatal hernia; chemotherapy; radiation therapy of the chest; surgery in the chest area; medications to prevent organ transplant rejection; immunosuppressive medications used to treat autoimmune diseases; aspirin and anti-inflammatory medications; chronic vomiting; obesity; alcohol and cigarette use; a family history of allergies or esophagitis.

• #3 Esophagitis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK442012/

  Esophagitis refers to inflammation or injury to the esophageal mucosa. One of the most common causes is gastroesophageal reflux, which can lead to erosive esophagitis. Other etiologies include radiation, infections, local injury caused by medications, pill esophagitis, and eosinophilic esophagitis (EoE). […] Multiple etiologies for esophagitis have been identified such as reflux esophagitis, Medication (Pills) induced esophagitis, infectious, eosinophilic and radiation esophagitis. […] Reflux or erosive esophagitis that occurs because of the reflux of gastric contents into the stomach leading to mucosal injury is one of the most common causes of esophagitis. […] Infection esophagitis can be caused by bacteria, viruses, fungal and parasitic microorganisms with the least common being bacteria and the most common being fungal.

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