Choroba wirusowa ebola
Zapobieganie i profilaktyka

Choroba wirusowa ebola (EVD) charakteryzuje się wysoką śmiertelnością (50-90%) i przenosi się przez bezpośredni kontakt z krwią lub płynami ustrojowymi zakażonych osób lub zwierząt. Profilaktyka obejmuje szczepienia zatwierdzonymi preparatami: ERVEBO (rVSV-ZEBOV) podawaną w pojedynczej dawce domięśniowej dla osób ≥18 lat oraz dwudawkowy schemat Zabdeno/Mvabea (Ad26.ZEBOV/MVA-BN-Filo) z odstępem 8 tygodni. Szczepienia te wykazały skuteczność w ograniczaniu epidemii, np. zaszczepiono ponad 300 000 osób w Prowincji Północne Kivu. Kobiety w ciąży i karmiące piersią mogą być szczepione podczas aktywnych ognisk choroby po uzyskaniu świadomej zgody. Kluczowe środki zapobiegawcze to unikanie kontaktu z płynami ustrojowymi, stosowanie środków ochrony osobistej (PPE), higiena rąk oraz monitorowanie stanu zdrowia przez 21 dni po ekspozycji. Pracownicy służby zdrowia powinni stosować pełne środki ochrony, w tym respiratory N95, podwójne rękawice i nieprzemakalne fartuchy, a także korzystać z systemu „partnera” przy zakładaniu i zdejmowaniu PPE.

Profilaktyka choroby wirusowej ebola

Choroba wirusowa ebola (EVD) jest rzadką, ale śmiertelną chorobą zakaźną, która może rozprzestrzeniać się wśród ludzi poprzez bezpośredni kontakt z krwią lub płynami ustrojowymi zakażonych osób lub zwierząt. Ze względu na wysoką śmiertelność sięgającą 50-90%, kluczowe znaczenie ma skuteczna profilaktyka i zapobieganie rozprzestrzenianiu się wirusa.1

Szczepienia przeciwko wirusowi ebola

Aktualnie dostępne są zatwierdzone szczepionki przeciwko chorobie wirusowej ebola, które stanowią istotny element profilaktyki w grupach wysokiego ryzyka:23

  • ERVEBO (rVSV-ZEBOV) – szczepionka zatwierdzona przez Amerykańską Agencję ds. Żywności i Leków (FDA) do zapobiegania chorobie wirusowej ebola wywoływanej przez Orthoebolavirus zairense (dawniej Zaire ebolavirus). Szczepionka jest zalecana dla osób dorosłych w wieku 18 lat i starszych, które mogą być narażone na kontakt z wirusem ebola.45
  • Szczepionka podawana jest w postaci pojedynczej dawki domięśniowej.6
  • Zabdeno/Mvabea (Ad26.ZEBOV/MVA-BN-Filo) – dwudawkowy schemat szczepienia, gdzie pierwszą dawkę Ad26.ZEBOV-GP podaje się w celu wstępnego wywołania odporności, a po 8 tygodniach podaje się drugą dawkę (MVA-BN-Filo) w celu wzmocnienia odporności.7

Szczepionki te wykazały znaczącą skuteczność w ograniczaniu rozprzestrzeniania się wirusa podczas epidemii. Podczas epidemii w Prowincji Północne Kivu szczepionką rVSV-ZEBOV zaszczepiono ponad 300 000 osób, a podczas wybuchu epidemii w 2020 roku w Prowincji Równikowej ponad 30 000 osób.8

Należy podkreślić, że kobiety w ciąży i karmiące piersią powinny mieć możliwość zaszczepienia się podczas aktywnego ogniska choroby wywoływanej przez wirusa ebola (gatunek Orthoebolavirus zairense) w ramach rygorystycznych badań lub zgodnie z protokołem użycia ze współczucia, po wyrażeniu świadomej zgody.910

Ogólne zasady profilaktyki

Podczas mieszkania lub podróżowania do regionów, gdzie wirus ebola może być obecny, należy podjąć następujące środki ostrożności:1112

  • Unikanie kontaktu z płynami ustrojowymi: Należy unikać bezpośredniego kontaktu z krwią i płynami ustrojowymi osób chorych lub wykazujących objawy infekcji.1314
  • Higiena osobista: Regularne mycie rąk mydłem i wodą lub używanie środków dezynfekujących na bazie alkoholu.1516
  • Unikanie kontaktu z nasieniem: Należy unikać kontaktu z nasieniem mężczyzn, którzy wyzdrowieli po chorobie ebola, dopóki badania nie wykażą, że wirus nie jest już obecny.1718
  • Unikanie skażonych przedmiotów: Unikanie kontaktu z ubraniami, pościelą, sprzętem medycznym lub innymi przedmiotami, które mogły mieć kontakt z płynami ustrojowymi zakażonej osoby.19
  • Unikanie kontaktu ze zwierzętami: Należy unikać kontaktu z nietoperzami, antylopami leśnymi i naczelnymi, a także krwią, płynami lub surowym mięsem tych zwierząt (lub innych nieznanych zwierząt).2021
  • Stosowanie środków ochronnych: Noszenie sprzętu ochronnego podczas kontaktu z osobami chorymi lub zmarłymi z powodu choroby wirusowej ebola, ich krwią i płynami ustrojowymi lub przedmiotami pokrytymi ich krwią lub płynami ustrojowymi.2223

Monitorowanie zdrowia po potencjalnym narażeniu

Po powrocie z obszaru z trwającym ogniskiem choroby ebola należy monitorować swój stan zdrowia przez 21 dni (co odpowiada okresowi inkubacji wirusa) i natychmiast zgłosić się po pomoc medyczną w przypadku wystąpienia objawów.2425 W przypadku podejrzenia infekcji na podstawie wstępnej oceny, natychmiastowa izolacja jest konieczna zanim przeprowadzone zostaną dalsze badania.26

Śledzenie kontaktów (np. rodzina, przyjaciele, współpracownicy) ma kluczowe znaczenie w profilaktyce rozprzestrzeniania się wirusa. Osoby, które zostały narażone na kontakt z wirusem w ciągu ostatnich 21 dni i nie wykazują objawów, muszą być monitorowane przez cały okres inkubacji w celu zapewnienia szybkiego rozpoznania objawów, po którym nastąpi natychmiastowa izolacja.27

Środki ostrożności dla pracowników służby zdrowia

Pracownicy służby zdrowia są szczególnie narażeni na ryzyko zakażenia podczas opieki nad pacjentami z chorobą wirusową ebola. Kluczowe środki ostrożności obejmują:2829

  • Środki ochrony osobistej (PPE): Należy nosić odpowiednie środki ochrony osobistej, w tym maski, gogle, fartuchy i rękawiczki. Szczególnie istotne jest prawidłowe zakładanie i zdejmowanie PPE.3031
  • System „partnera”: Ważne jest korzystanie z pomocy „partnera” podczas pobytu w obszarze opieki nad pacjentem oraz podczas zakładania i zdejmowania środków ochrony osobistej, aby zapewnić bezpieczną praktykę.32
  • Standardowe środki ostrożności: Należy zawsze stosować standardowe środki ostrożności podczas opieki nad pacjentami, niezależnie od ich przypuszczalnej diagnozy. Obejmują one podstawową higienę rąk, higienę dróg oddechowych, stosowanie środków ochrony osobistej, bezpieczne praktyki iniekcji oraz bezpieczne i godne praktyki pogrzebowe.33
  • Dodatkowe środki kontroli zakażeń: Pracownicy służby zdrowia opiekujący się pacjentami z podejrzeniem lub potwierdzeniem choroby wirusowej ebola powinni stosować dodatkowe środki kontroli zakażeń, aby zapobiec kontaktowi z krwią i płynami ustrojowymi pacjentów oraz skażonymi powierzchniami lub materiałami.34

Profilaktyka poekspozycyjna (PEP)

Profilaktyka poekspozycyjna jest zalecana u pacjentów z grupy wysokiego ryzyka, na przykład u osób mających kontakt ze skórą lub błonami śluzowymi zakażonego pacjenta (żywego lub zmarłego) lub jego płynami ustrojowymi, po urazie ostrymi narzędziami lub po kontakcie ze skażonymi rękawiczkami lub odzieżą.3536

Możliwe opcje do rozważenia w ramach PEP obejmują:37

Oprócz tych interwencji, niezbędne jest wsparcie psychologiczne dla pracowników służby zdrowia narażonych na kontakt z niebezpiecznymi patogenami.43

Badania wykazały, że pracownicy służby zdrowia z pośrednim lub wysokim ryzykiem rozwoju choroby wirusowej ebola po narażeniu na kontakt z wirusem, którzy otrzymali profilaktykę poekspozycyjną, nie rozwinęli choroby. W jednym z badań, czterech pracowników służby zdrowia ocenionych jako osoby o średnim lub wysokim ryzyku zachorowania na EVD otrzymało profilaktykę poekspozycyjną z zastosowaniem doustnego fawipirawiru przez 10 dni. Dodatkowo dwóch z czterech pacjentów leczono również przeciwciałami monoklonalnymi przeciwko glikoproteinom wirusa ebola.4445

Zapobieganie transmisji seksualnej

Wirus ebola może utrzymywać się w nasieniu mężczyzn, którzy wyzdrowieli z choroby wirusowej ebola, przez dłuższy czas. Aby zmniejszyć ryzyko transmisji, zaleca się:4647

  • Oferowanie doradztwa dla mężczyzn, którzy przeszli chorobę, i ich partnerów seksualnych w celu poinformowania o potencjalnym ryzyku i wsparcia w stosowaniu bezpieczniejszych praktyk seksualnych (w tym stosowania prezerwatyw i dobrej higieny osobistej).48
  • Oferowanie comiesięcznych badań nasienia do czasu uzyskania dwóch kolejnych wyników negatywnych.49
  • Po dwóch kolejnych negatywnych testach, osoby, które przeszły chorobę mogą bezpiecznie wrócić do normalnych praktyk seksualnych przy zminimalizowanym ryzyku transmisji wirusa.50
  • W przypadku braku programu badania nasienia, mężczyźni, którzy przeszli chorobę powinni przestrzegać bezpieczniejszych praktyk seksualnych przez 12 miesięcy.5152

Kontrola ognisk choroby

Skuteczna kontrola ognisk choroby wirusowej ebola opiera się na zastosowaniu szeregu interwencji:5354

  • Zaangażowanie społeczności: Kluczowe znaczenie dla skutecznej kontroli ognisk ma zaangażowanie społeczności.5556
  • Opieka kliniczna: Zapewnienie odpowiedniej opieki medycznej dla zakażonych osób.57
  • Nadzór i śledzenie kontaktów: Identyfikacja i monitorowanie osób, które miały kontakt z zakażonymi.5859
  • Usługi laboratoryjne: Szybka i dokładna diagnostyka przypadków.60
  • Zapobieganie i kontrola zakażeń w placówkach zdrowotnych: Wdrażanie odpowiednich protokołów zapobiegania zakażeniom.6162
  • Bezpieczne i godne pochówki: Prawidłowe postępowanie ze zwłokami osób zmarłych z powodu choroby wirusowej ebola.6364
  • Mobilizacja społeczna: Edukacja społeczności na temat choroby i sposobów jej zapobiegania.65

Środki zapobiegawcze dla osób mieszkających w krajach dotkniętych epidemią obejmują utrzymywanie dobrej higieny i czystego środowiska, oddzielanie osób zdrowych od chorych w celu zapobiegania dalszemu rozprzestrzenianiu się choroby oraz zapewnianie opieki potwierdzonym pacjentom.66

Profilaktyka w placówkach opieki zdrowotnej

Placówki opieki zdrowotnej odgrywają kluczową rolę w zapobieganiu rozprzestrzeniania się choroby wirusowej ebola. Ważne jest wdrożenie odpowiednich protokołów i procedur w celu ochrony zarówno pacjentów, jak i personelu medycznego.6768

Identyfikacja i izolacja pacjentów

Wczesna identyfikacja i izolacja potencjalnie zakażonych osób jest kluczowym krokiem w zapobieganiu rozprzestrzeniania się choroby wirusowej ebola, szczególnie w przypadku pracowników, którzy mogą być narażeni na kontakt z osobą zarażoną wirusem.6970

  • Każda organizacja opieki zdrowotnej powinna opracować kompleksowe polityki i procedury dotyczące zakładania i zdejmowania środków ochrony osobistej.71
  • Pacjenci z podejrzeniem zakażenia powinni być natychmiast umieszczani w prywatnym pokoju z łazienką lub przykrytym pojemnikiem przy łóżku.72
  • Należy minimalizować liczbę personelu mającego kontakt z pacjentem i prowadzić rejestr wszystkich osób wchodzących do pokoju pacjenta.73
  • Wykonywać tylko niezbędne testy i procedury oraz unikać procedur generujących aerozole.74

Kontrola zakażeń i dezynfekcja

Właściwa kontrola zakażeń i dezynfekcja są kluczowe w zapobieganiu rozprzestrzeniania się wirusa ebola w placówkach opieki zdrowotnej:7576

  • Pracownicy muszą być chronieni przed narażeniem na szkodliwe chemikalia podczas czyszczenia i dezynfekcji obszarów skażonych krwią i/lub płynami ustrojowymi podejrzanymi lub potwierdzonymi o zakażenie wirusem ebola.77
  • Środki dezynfekujące skuteczne przeciwko wirusowi ebola są opisane na listach Agencji Ochrony Środowiska USA: Lista L (Środki dezynfekujące do stosowania przeciwko wirusowi ebola) i Lista Q (Środki dezynfekujące do zwalczania nowo pojawiających się patogenów wirusowych).78
  • Należy postępować zgodnie z wytycznymi CDC dotyczącymi kontroli zakażeń środowiskowych w zakresie czyszczenia i dezynfekcji pokoju/obszaru pacjenta.79

Wirus ebola może przetrwać przez kilka godzin na suchych powierzchniach, takich jak klamki i blaty. Może również przeżyć do kilku dni w temperaturze pokojowej w płynach ustrojowych. Wirus może być zabity przy użyciu zarejestrowanego przez Agencję Ochrony Środowiska USA szpitalnego środka dezynfekującego z etykietą dla wirusa nieopłaszczonego.8081

Środki ochrony osobistej dla personelu medycznego

Personel medyczny musi być odpowiednio chroniony podczas opieki nad pacjentami z podejrzeniem lub potwierdzeniem choroby wirusowej ebola:8283

  • Należy zapewnić respiratory, ochronę głowy, twarzy i rąk dla pracowników, którzy mogą być narażeni na kontakt z krwią lub płynami ustrojowymi oraz z powierzchni środowiskowych, gdzie możliwe jest skażenie wirusem ebola.84
  • Personel powinien nosić odpowiednie środki ochrony osobistej, w tym odzież ochronną, maski, rękawice, okulary ochronne i inną ochronę, zgodnie z zaleceniami pracodawcy.85
  • W przypadku potwierdzonego pacjenta z EVD, CDC zaleca nieprzemakalne fartuchy lub kombinezony, stosowanie pełnej osłony twarzy, respirator NIOSH zatwierdzony, dopasowany do twarzy N95 lub wyższą ochronę, podwójne rękawice, ochraniacze na buty i fartuch.86

Personel zajmujący się sprzątaniem powinien nosić co najmniej taki sam poziom ochrony jak pracownicy służby zdrowia zapewniający opiekę pacjentowi.87

Edukacja i świadomość społeczna

Podnoszenie świadomości na temat czynników ryzyka i środków ochronnych, które jednostki mogą podjąć, jest skutecznym sposobem na zmniejszenie transmisji wirusa u ludzi.88

Przekazywanie informacji o ryzyku

Komunikaty dotyczące redukcji ryzyka powinny koncentrować się na kilku czynnikach:8990

  • Zmniejszenie ryzyka transmisji między ludźmi wynikającego z bezpośredniego lub bliskiego kontaktu z zakażonymi osobami, szczególnie z ich płynami ustrojowymi.91
  • Unikanie bliskiego kontaktu fizycznego z pacjentami chorymi na chorobę wirusową ebola. Pacjenci powinni być izolowani w wyznaczonym ośrodku leczenia w celu wczesnej opieki i uniknięcia transmisji w domu.92
  • Kampanie edukacji publicznej są ważne dla podnoszenia świadomości na temat sposobów rozprzestrzeniania się choroby wirusowej ebola i kroków, które ludzie mogą podjąć, aby się chronić.93

Programy edukacyjne dla społeczności

Działania edukacyjne są jednymi z najważniejszych długoterminowych środków zapobiegawczych:9495

  • Rozpowszechnianie wiedzy na temat ochrony przed chorobą, jej objawów i postępowania w przypadku możliwego zakażenia może zapobiec przyszłym epidemiom.96
  • UNICEF i partnerzy kontynuują wykorzystywanie struktur edukacyjnych jako kanałów rozpowszechniania informacji, zaangażowania społeczności oraz zaangażowania z lokalnymi ośrodkami wczesnej edukacji, szkołami podstawowymi i średnimi w celu przekazywania wiadomości dotyczących eboli podczas zgromadzeń szkolnych i spotkań stowarzyszeń rodziców i nauczycieli.97

W Sierra Leone podczas wybuchu epidemii w 2014 roku pracownicy odwiedzali domy, aby dotrzeć do 1,5 miliona gospodarstw domowych i dzielić się informacjami na temat sposobów, w jakie rodziny mogą chronić się przed chorobą wirusową ebola, pomagając w spowolnieniu transmisji.98

Kontrola środowiskowa i higiena

Utrzymanie odpowiedniej higieny i czystego środowiska jest ważnym elementem zapobiegania rozprzestrzenianiu się wirusa ebola.99

Dezynfekcja i usuwanie odpadów

Odpowiednia dezynfekcja i usuwanie odpadów są kluczowe w zapobieganiu transmisji wirusa ebola:100

  • Skażone przedmioty pacjentów, takie jak ubrania i ręczniki, powinny być również dezynfekowane lub palone bez zwłoki.101
  • Należy dokładnie czyścić i dezynfekować powierzchnie, które mogły zostać skażone.102
  • Departament Transportu USA uznaje odpady pochodzące od pacjentów z chorobą wirusową ebola za kategorię A.103

Praktyki higieny osobistej

Dobre praktyki higieny osobistej są kluczowe w zapobieganiu infekcji:104105

  • Regularne mycie rąk mydłem i wodą. Używanie środka dezynfekującego na bazie alkoholu, jeśli mydło i woda nie są dostępne.106
  • Praktykowanie dobrej higieny, takiej jak mycie rąk mydłem i wodą lub środkiem do dezynfekcji rąk na bazie alkoholu i unikanie kontaktu z krwią i płynami ustrojowymi innych osób.107
  • Dezynfekowanie pościeli i ubrań osoby podejrzanej o śmierć z powodu eboli za pomocą środków dezynfekujących.108

Profilaktyka podczas podróży

Osoby podróżujące do lub przebywające w obszarze dotkniętym wybuchem epidemii ebola powinny przestrzegać określonych środków ostrożności:109110

  • Unikanie obszarów z aktywną epidemią: Należy unikać odwiedzania obszarów z znanymi ogniskami choroby.111112
  • Praktykowanie ostrożnej higieny: Mycie rąk mydłem i wodą lub środkiem do dezynfekcji rąk na bazie alkoholu. Unikanie kontaktu z krwią i płynami ustrojowymi.113
  • Unikanie kontaktu z chorymi osobami: Unikanie kontaktu z osobami, które mają gorączkę, wymiotują lub wydają się chore.114
  • Unikanie kontaktu z przedmiotami potencjalnie skażonymi: Nie dotykanie przedmiotów, które mogły mieć kontakt z krwią lub płynami ustrojowymi zakażonej osoby. Dotyczy to ubrań, pościeli, igieł i sprzętu medycznego.115
  • Unikanie rytuałów pogrzebowych: Unikanie rytuałów pogrzebowych lub pochówkowych, które wymagają dotykania ciała osoby zmarłej z powodu eboli.116117
  • Unikanie kontaktu ze zwierzętami: Unikanie kontaktu z nietoperzami i naczelnymi lub krwią, płynami i surowym mięsem przygotowanym z tych zwierząt.118

Po powrocie z podróży należy zwrócić uwagę na swoje zdrowie przez 21 dni. W przypadku wystąpienia objawów eboli, należy natychmiast zgłosić się po pomoc medyczną. Należy poinformować lekarza o pobycie w kraju, gdzie występuje ebola.119120

Współpraca międzynarodowa w zapobieganiu epidemiom

Skuteczna kontrola i zapobieganie epidemiom ebola wymaga ścisłej współpracy międzynarodowej i koordynacji działań.121122

Rola organizacji międzynarodowych

Organizacje międzynarodowe odgrywają kluczową rolę w koordynacji działań zapobiegawczych i kontrolnych:123124

  • PAHO współpracuje z krajami w regionie w celu wzmocnienia ich gotowości do wykrywania i szybkiego reagowania na możliwy importowany przypadek eboli.125
  • Dyrektor PAHO utworzył grupę zadaniową i operacyjną grupę roboczą, która doradza i wspiera wdrażanie zaleceń Międzynarodowego Komitetu Kryzysowego Międzynarodowych Przepisów Zdrowotnych (IHR) oraz koordynuje reakcję na możliwe wprowadzenie choroby wirusowej ebola do Ameryki.126
  • Szybka i skuteczna reakcja w Ugandzie pokazała wartość inwestowania w gotowość. Trzy potwierdzone przypadki zostały szybko wykryte i izolowane.127

CDC, Światowa Organizacja Zdrowia (WHO) i inne organizacje międzynarodowe zapewniają wytyczne, wsparcie i zasoby dla krajów dotkniętych wybuchem epidemii. Organizacja Global Ebola Response stwierdza, że kraje duże i małe podjęły działania w celu zapewnienia lekarzy, mobilnych klinik i finansowania w celu zwalczania wirusa.128

Wsparcie wojskowe i logistyczne

Siły zbrojne są niezbędne, gdy lokalne systemy zdrowia publicznego są przeciążone lub w przypadku, gdy epidemia ebola wymyka się spod kontroli:129130

  • Siły wojskowe powinny reagować w odpowiednim czasie na wybuch epidemii ebola, jeśli staje się ona coraz większym zagrożeniem dla społeczności międzynarodowej.131
  • Skuteczna kontrola wybuchu epidemii ebola jest nie tylko kwestią kryzysową dla społeczności medycznej, ale także misją ochrony zdrowia dla sił zbrojnych.132

Zapobieganie transmisji w społecznościach

Zapobieganie transmisji wirusa ebola w społecznościach wymaga kompleksowego podejścia obejmującego edukację, odpowiednie praktyki kulturowe i szybką interwencję.133

Modyfikacja praktyk kulturowych

Niektóre tradycyjne praktyki kulturowe mogą zwiększać ryzyko transmisji wirusa ebola i wymagają modyfikacji:134

  • Modyfikacja tradycyjnych praktyk pogrzebowych: Istnieje pilna potrzeba modyfikacji tradycyjnych praktyk pogrzebowych, które często stanowią źródła zakażenia ze względu na kontakt z płynami ustrojowymi zmarłych osób. Ponieważ jest to kwestia wrażliwa kulturowo, kluczowe znaczenie ma odpowiednia edukacja, wsparcie i działania informacyjne.135136
  • Bezpieczne praktyki pogrzebowe: Bezpieczne i godne pochówki pomagają zapobiegać transmisji, jednocześnie podkreślając włączenie członków rodziny i zachęcając do obrzędów religijnych.137
  • Unikanie kontaktu z dziczyzną: Należy unikać mięsa z upolowanych dzikich zwierząt (tzw. bushmeat). W miejscach, gdzie konsumpcja takiego mięsa trwa nadal, konieczne jest zachęcanie do bezpieczniejszych procedur uboju i obchodzenia się z nim.138139

Ochrona dzieci i grup wrażliwych

Szczególną uwagę należy zwrócić na ochronę dzieci i innych grup wrażliwych podczas wybuchów epidemii ebola:140

  • Adaptacje struktury jednostek leczenia eboli (ETU): Struktura ETU koniecznie ogranicza obecność niezakażonych opiekunów, co może tworzyć otoczenie, które nie jest bezpieczne lub komfortowe dla dzieci. Adaptacje tej struktury, w tym rekrutacja osób, które przeżyły chorobę, aby pomóc w opiece nad dziećmi, mogą pomóc w rozwiązaniu tych trudności.141
  • Programy opieki nad osobami, które przeżyły: Programy opieki nad osobami, które przeżyły chorobę, powinny obejmować opiekę nad kobietami w ciąży i karmiącymi piersią po ich wyzdrowieniu.142

W przypadku wybuchów epidemii ebola UNICEF i partnerzy kontynuują wspieranie szybkich ocen, zakupu i dystrybucji niezbędnych środków higienicznych, orientacji i mentoringu pracowników służby zdrowia i osób odpowiedzialnych za zasoby WASH w zakresie infekcji, zapobiegania i kontroli (IPC).143

Kolejne rozdziały

Zapraszamy do dalszego czytania naszego leksykonu.

Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.

  1. 12.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Ebola Virus Disease: Prevention and Control Measures for Hospitals | Institut national de santé publique du Québec
    https://www.inspq.qc.ca/en/publications/1890
    Ebola virus disease has a fatality rate of 50% to 90%. […] The CINQ recommends stronger measures to take into account possible airborne transmission, significant environmental contamination by blood, body fluids, secretions or excretions, and high Ebola virus disease fatality. […] Hospitals must implement the measures necessary to prevent the transmission of Ebola virus disease.
  • #2 Ebola Disease Basics | Ebola | CDC
    https://www.cdc.gov/ebola/about/index.html
    There is an FDA-approved vaccine for the prevention of Ebola virus (species Zaire orthoebolavirus). […] When living in or traveling to regions where viruses that spread Ebola disease may be present, take steps to protect yourself. […] Avoid contact with body fluids from people and animals, including […] Wear protective equipment if you come in contact with people who are sick or have died from Ebola disease, their blood and bodily fluids, or objects covered with their blood or body fluids. […] If you return from an area with an ongoing Ebola outbreak, monitor your health for 21 days. Seek medical care immediately if you develop symptoms of Ebola disease. […] The U.S. Food and Drug Administration has approved ERVEBO for the prevention of Ebola disease (species Orthoebolavirus zairense only). Vaccination is recommended for U.S. adults 18 years and older who are at potential risk of exposure to the Ebola virus.
  • #3 First FDA-approved vaccine for the prevention of Ebola virus disease, marking a critical milestone in public health preparedness and response | FDA
    https://www.fda.gov/news-events/press-announcements/first-fda-approved-vaccine-prevention-ebola-virus-disease-marking-critical-milestone-public-health
    The U.S. Food and Drug Administration announced today the approval of Ervebo, the first FDA-approved vaccine for the prevention of Ebola virus disease (EVD), caused by Zaire ebolavirus in individuals 18 years of age and older. […] Vaccination is essential to help prevent outbreaks and to stop the Ebola virus from spreading when outbreaks do occur, said Peter Marks, M.D., Ph.D., director of the FDAs Center for Biologics Evaluation and Research. […] With or without vaccination, it is critical to implement appropriate infection control and prevention measures as part of efforts to prevent the spread of EVD. […] The FDA is committed to continuing our work across the U.S. government and with our international partners to prevent future Ebola outbreaks and mitigate the current outbreak in the DRC, reflecting our nations commitment to preparing for and responding to biological threats, like Ebola.
  • #4 Ebola Disease Basics | Ebola | CDC
    https://www.cdc.gov/ebola/about/index.html
    There is an FDA-approved vaccine for the prevention of Ebola virus (species Zaire orthoebolavirus). […] When living in or traveling to regions where viruses that spread Ebola disease may be present, take steps to protect yourself. […] Avoid contact with body fluids from people and animals, including […] Wear protective equipment if you come in contact with people who are sick or have died from Ebola disease, their blood and bodily fluids, or objects covered with their blood or body fluids. […] If you return from an area with an ongoing Ebola outbreak, monitor your health for 21 days. Seek medical care immediately if you develop symptoms of Ebola disease. […] The U.S. Food and Drug Administration has approved ERVEBO for the prevention of Ebola disease (species Orthoebolavirus zairense only). Vaccination is recommended for U.S. adults 18 years and older who are at potential risk of exposure to the Ebola virus.
  • #5 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Vaccines […] The World Health Organization (WHO) has prequalified the vaccine, and several African countries have approved it for the prevention of Ebola disease caused by the Ebola virus (species Orthoebolavirus zairense). […] The vaccine is administered as a single intramuscular dose. […] Pregnant and breast-feeding women should be offered vaccination with the vaccine during an active outbreak caused by Ebola virus (species Orthoebolavirus zairense) in affected areas, in the context of rigorous research or in accordance with a compassionate use protocol, with informed consent. […] Contact tracing (e.g., family, friends, work colleagues) is essential. […] People who have been exposed to the virus within the last 21 days and who are asymptomatic need to be monitored for the duration of the incubation period in order to ensure rapid recognition of symptoms followed by immediate isolation.
  • #6 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Vaccines […] The World Health Organization (WHO) has prequalified the vaccine, and several African countries have approved it for the prevention of Ebola disease caused by the Ebola virus (species Orthoebolavirus zairense). […] The vaccine is administered as a single intramuscular dose. […] Pregnant and breast-feeding women should be offered vaccination with the vaccine during an active outbreak caused by Ebola virus (species Orthoebolavirus zairense) in affected areas, in the context of rigorous research or in accordance with a compassionate use protocol, with informed consent. […] Contact tracing (e.g., family, friends, work colleagues) is essential. […] People who have been exposed to the virus within the last 21 days and who are asymptomatic need to be monitored for the duration of the incubation period in order to ensure rapid recognition of symptoms followed by immediate isolation.
  • #7 Ebola virus disease in children: epidemiology, pathogenesis, management, and prevention | Pediatric Research
    https://www.nature.com/articles/s41390-023-02873-y
    The rVSV-ZEBOV vaccine is a live, attenuated recombinant vesicular stomatitis virus (VSV) in which the native GP is replaced with EBOV GP. […] The Ad26.ZEBOV/MVA-BN-Filo regimen is a two-dose heterologous strategy: a dose of monovalent Ad26.ZEBOV designed to prime immunity and provide EBOV-GP-specific immunity, followed eight weeks later by multivalent MVA-BN-Filo vaccine designed to boost immunity and provide immunity to multiple filovirus species (EBOV, SUDV, TAFV, and Marburg virus). […] The safety and immunogenicity of rVSV-ZEBOV and Ad26.ZEBOV/MVA-BN-Filo regimens were directly compared in recent randomized trials that included 1400 adults and 1401 children. […] Across trials for both vaccines, no deaths and low incidence of serious adverse events related to vaccination occurred.
  • #8 Treatment and prevention of Ebola and Sudan virus disease – UpToDate
    https://www.uptodate.com/contents/treatment-and-prevention-of-ebola-virus-disease
    Infection prevention: Precautions for preventing transmission of infection […] The experience of the 2014 to 2016 West African epidemic demonstrated that the mortality associated with Ebola virus disease may be reduced through adequate supportive care […] It also accelerated the investigation of therapies and vaccines for treatment and prevention of Ebola virus disease […] In addition, the rVSV-ZEBOV vaccine, first found to provide significant protection in West Africa, was given to more than 300,000 people during the course of the North Kivu epidemic and to more than 30,000 people during the 2020 outbreak in the Équateur Province.
  • #9 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Vaccines […] The World Health Organization (WHO) has prequalified the vaccine, and several African countries have approved it for the prevention of Ebola disease caused by the Ebola virus (species Orthoebolavirus zairense). […] The vaccine is administered as a single intramuscular dose. […] Pregnant and breast-feeding women should be offered vaccination with the vaccine during an active outbreak caused by Ebola virus (species Orthoebolavirus zairense) in affected areas, in the context of rigorous research or in accordance with a compassionate use protocol, with informed consent. […] Contact tracing (e.g., family, friends, work colleagues) is essential. […] People who have been exposed to the virus within the last 21 days and who are asymptomatic need to be monitored for the duration of the incubation period in order to ensure rapid recognition of symptoms followed by immediate isolation.
  • #10 Ebola Virus Disease – PAHO/WHO | Pan American Health Organization
    https://www.paho.org/en/topics/ebola-virus-disease
    Ebola virus disease (EVD), formerly known as Ebola hemorrhagic fever, is a rare but severe, often fatal illness in humans. […] Community engagement is key to successfully controlling outbreaks. […] Good outbreak control relies on applying a package of interventions, namely case management, infection prevention and control practices, surveillance and contact tracing, a good laboratory service, safe and dignified burials and social mobilization. […] Vaccines to protect against Ebola have been developed and have been used to help control the spread of Ebola outbreaks in Guinea and in the Democratic Republic of the Congo (DRC). […] Pregnant and breastfeeding women with Ebola should be offered early supportive care. Likewise vaccine prevention and experimental treatment should be offered under the same conditions as for non-pregnant population.
  • #11 Ebola Disease Basics | Ebola | CDC
    https://www.cdc.gov/ebola/about/index.html
    There is an FDA-approved vaccine for the prevention of Ebola virus (species Zaire orthoebolavirus). […] When living in or traveling to regions where viruses that spread Ebola disease may be present, take steps to protect yourself. […] Avoid contact with body fluids from people and animals, including […] Wear protective equipment if you come in contact with people who are sick or have died from Ebola disease, their blood and bodily fluids, or objects covered with their blood or body fluids. […] If you return from an area with an ongoing Ebola outbreak, monitor your health for 21 days. Seek medical care immediately if you develop symptoms of Ebola disease. […] The U.S. Food and Drug Administration has approved ERVEBO for the prevention of Ebola disease (species Orthoebolavirus zairense only). Vaccination is recommended for U.S. adults 18 years and older who are at potential risk of exposure to the Ebola virus.
  • #12 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    The following preventive measures are recommended for people living in or traveling to an area affected by an outbreak. […] Avoid contact with body and body fluids from people who are sick. […] Avoid contact with semen from someone who has recovered from Ebola disease until testing shows the virus is no longer present. […] Avoid contact with clothes, bedding, medical equipment, or other items that may have touched an infected persons body fluids. […] Avoid contact with the body of someone who is suspected or confirmed to have Ebola disease (e.g., during a funeral or burial practice). […] Avoid contact with bats, forest antelopes, and primates, and blood, fluids, or raw meat from these animals (or other unknown animals). […] Wear protective equipment when in contact with people who are sick or have died from Ebola disease, their body fluids, or objects covered with their body fluids.
  • #13 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    The following preventive measures are recommended for people living in or traveling to an area affected by an outbreak. […] Avoid contact with body and body fluids from people who are sick. […] Avoid contact with semen from someone who has recovered from Ebola disease until testing shows the virus is no longer present. […] Avoid contact with clothes, bedding, medical equipment, or other items that may have touched an infected persons body fluids. […] Avoid contact with the body of someone who is suspected or confirmed to have Ebola disease (e.g., during a funeral or burial practice). […] Avoid contact with bats, forest antelopes, and primates, and blood, fluids, or raw meat from these animals (or other unknown animals). […] Wear protective equipment when in contact with people who are sick or have died from Ebola disease, their body fluids, or objects covered with their body fluids.
  • #14 Ebola disease: Prevention and risks – Canada.ca
    https://www.canada.ca/en/public-health/services/diseases/ebola/prevention-ebola.html
    Preventing Ebola disease […] There are things you can do to reduce your risk if you: […] Practice good hygiene […] Wash your hands frequently with soap and water. Use an alcohol-based hand sanitizer if soap and water are not available. […] Avoid direct contact with other people’s body fluids […] Avoid direct, unprotected contact with the body fluids and tissues of: […] Avoid high-risk areas and activities […] Avoid all places and activities that could result in exposure. This includes places where sick people are being cared for without appropriate infection control measures. […] If you can’t avoid high-risk areas or activities, reduce your risk by taking proper precautions, such as wearing: […] Avoid unprotected sexual activity […] Avoid sexual activity with anyone who is currently sick, including oral, vaginal or anal sex. […] Follow safe burial practices […] Avoid direct, unprotected contact with the body of a person who died of Ebola disease or an unknown illness. […] Avoid contact with wild animals […] Avoid contact with live and dead wild animals, including:
  • #15 Ebola disease: Prevention and risks – Canada.ca
    https://www.canada.ca/en/public-health/services/diseases/ebola/prevention-ebola.html
    Preventing Ebola disease […] There are things you can do to reduce your risk if you: […] Practice good hygiene […] Wash your hands frequently with soap and water. Use an alcohol-based hand sanitizer if soap and water are not available. […] Avoid direct contact with other people’s body fluids […] Avoid direct, unprotected contact with the body fluids and tissues of: […] Avoid high-risk areas and activities […] Avoid all places and activities that could result in exposure. This includes places where sick people are being cared for without appropriate infection control measures. […] If you can’t avoid high-risk areas or activities, reduce your risk by taking proper precautions, such as wearing: […] Avoid unprotected sexual activity […] Avoid sexual activity with anyone who is currently sick, including oral, vaginal or anal sex. […] Follow safe burial practices […] Avoid direct, unprotected contact with the body of a person who died of Ebola disease or an unknown illness. […] Avoid contact with wild animals […] Avoid contact with live and dead wild animals, including:
  • #16
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Outbreak containment measures include safe and dignified burial of the deceased, identifying people who may have been in contact with someone infected with Ebola disease and monitoring their health for 21 days, separating the healthy from the sick to prevent further spread and providing care to confirmed patients. Maintaining good hygiene and a clean environment are also important. […] Health-care workers should always take standard precautions when caring for patients, regardless of their presumed diagnosis. These include basic hand hygiene, respiratory hygiene, use of personal protective equipment (to block splashes or other contact with infected materials), safe injection practices and safe and dignified burial practices. […] Health-care workers caring for patients with suspected or confirmed Ebola disease should apply extra infection control measures to prevent contact with the patients blood and body fluids and contaminated surfaces or materials such as clothing and bedding.
  • #17 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    The following preventive measures are recommended for people living in or traveling to an area affected by an outbreak. […] Avoid contact with body and body fluids from people who are sick. […] Avoid contact with semen from someone who has recovered from Ebola disease until testing shows the virus is no longer present. […] Avoid contact with clothes, bedding, medical equipment, or other items that may have touched an infected persons body fluids. […] Avoid contact with the body of someone who is suspected or confirmed to have Ebola disease (e.g., during a funeral or burial practice). […] Avoid contact with bats, forest antelopes, and primates, and blood, fluids, or raw meat from these animals (or other unknown animals). […] Wear protective equipment when in contact with people who are sick or have died from Ebola disease, their body fluids, or objects covered with their body fluids.
  • #18
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    To mitigate the risk of this transmission, a semen testing programme should be implemented to: […] offer counselling to male survivors and their sexual partners to inform them of the potential risk and support them adhering to safer sex practices (including condom provision and good hand and personal hygiene); […] offer monthly semen testing until they have had two consecutive negative test results; and […] after two consecutive negative tests, survivors can safely resume normal sexual practices with minimized risk of virus transmission. […] In the absence of a semen testing programme, male survivors should follow safer sex practices for 12 months. […] Survivor care programmes should encompass care for pregnant and breastfeeding women after their recovery.
  • #19 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    The following preventive measures are recommended for people living in or traveling to an area affected by an outbreak. […] Avoid contact with body and body fluids from people who are sick. […] Avoid contact with semen from someone who has recovered from Ebola disease until testing shows the virus is no longer present. […] Avoid contact with clothes, bedding, medical equipment, or other items that may have touched an infected persons body fluids. […] Avoid contact with the body of someone who is suspected or confirmed to have Ebola disease (e.g., during a funeral or burial practice). […] Avoid contact with bats, forest antelopes, and primates, and blood, fluids, or raw meat from these animals (or other unknown animals). […] Wear protective equipment when in contact with people who are sick or have died from Ebola disease, their body fluids, or objects covered with their body fluids.
  • #20 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    The following preventive measures are recommended for people living in or traveling to an area affected by an outbreak. […] Avoid contact with body and body fluids from people who are sick. […] Avoid contact with semen from someone who has recovered from Ebola disease until testing shows the virus is no longer present. […] Avoid contact with clothes, bedding, medical equipment, or other items that may have touched an infected persons body fluids. […] Avoid contact with the body of someone who is suspected or confirmed to have Ebola disease (e.g., during a funeral or burial practice). […] Avoid contact with bats, forest antelopes, and primates, and blood, fluids, or raw meat from these animals (or other unknown animals). […] Wear protective equipment when in contact with people who are sick or have died from Ebola disease, their body fluids, or objects covered with their body fluids.
  • #21 Ebola virus disease
    https://www.ecdc.europa.eu/en/ebola-and-marburg-fevers
    The risk of becoming infected is considered to be very low if infection prevention and control measures are followed, although the mortality rate is approximately 65% of diagnosed cases. […] To prevent the infection, it is recommended to: […] avoid habitats where ebolaviruses may be present […] avoid handling or eating bushmeat […] avoid close contact with wild animals in areas where ebolaviruses may be present. […] Two vaccines have been approved for use in many countries to protect against a type of Ebola virus called Zaire ebolavirus. However, there are no vaccines available against other types of Ebola virus.
  • #22 Ebola Disease Basics | Ebola | CDC
    https://www.cdc.gov/ebola/about/index.html
    There is an FDA-approved vaccine for the prevention of Ebola virus (species Zaire orthoebolavirus). […] When living in or traveling to regions where viruses that spread Ebola disease may be present, take steps to protect yourself. […] Avoid contact with body fluids from people and animals, including […] Wear protective equipment if you come in contact with people who are sick or have died from Ebola disease, their blood and bodily fluids, or objects covered with their blood or body fluids. […] If you return from an area with an ongoing Ebola outbreak, monitor your health for 21 days. Seek medical care immediately if you develop symptoms of Ebola disease. […] The U.S. Food and Drug Administration has approved ERVEBO for the prevention of Ebola disease (species Orthoebolavirus zairense only). Vaccination is recommended for U.S. adults 18 years and older who are at potential risk of exposure to the Ebola virus.
  • #23 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    The following preventive measures are recommended for people living in or traveling to an area affected by an outbreak. […] Avoid contact with body and body fluids from people who are sick. […] Avoid contact with semen from someone who has recovered from Ebola disease until testing shows the virus is no longer present. […] Avoid contact with clothes, bedding, medical equipment, or other items that may have touched an infected persons body fluids. […] Avoid contact with the body of someone who is suspected or confirmed to have Ebola disease (e.g., during a funeral or burial practice). […] Avoid contact with bats, forest antelopes, and primates, and blood, fluids, or raw meat from these animals (or other unknown animals). […] Wear protective equipment when in contact with people who are sick or have died from Ebola disease, their body fluids, or objects covered with their body fluids.
  • #24 Ebola Disease Basics | Ebola | CDC
    https://www.cdc.gov/ebola/about/index.html
    There is an FDA-approved vaccine for the prevention of Ebola virus (species Zaire orthoebolavirus). […] When living in or traveling to regions where viruses that spread Ebola disease may be present, take steps to protect yourself. […] Avoid contact with body fluids from people and animals, including […] Wear protective equipment if you come in contact with people who are sick or have died from Ebola disease, their blood and bodily fluids, or objects covered with their blood or body fluids. […] If you return from an area with an ongoing Ebola outbreak, monitor your health for 21 days. Seek medical care immediately if you develop symptoms of Ebola disease. […] The U.S. Food and Drug Administration has approved ERVEBO for the prevention of Ebola disease (species Orthoebolavirus zairense only). Vaccination is recommended for U.S. adults 18 years and older who are at potential risk of exposure to the Ebola virus.
  • #25 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Monitor health for 21 days after returning from an area with an ongoing outbreak and seek immediate medical care if symptoms develop. […] If infection is suspected based on initial screening, immediate isolation is warranted before any further workup is carried out. […] The highest risk facing healthcare workers when looking after infected patients is inadvertently touching their own faces or neck under the face shield during patient care, and removing (doffing) personal protective equipment (PPE). […] Healthcare workers should understand the following basic principles of using PPE. […] The importance of a „buddy” when inside the patient care area and during donning and doffing, to ensure safe practice cannot be overstated, together with guidance from independent monitors if available.
  • #26 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Monitor health for 21 days after returning from an area with an ongoing outbreak and seek immediate medical care if symptoms develop. […] If infection is suspected based on initial screening, immediate isolation is warranted before any further workup is carried out. […] The highest risk facing healthcare workers when looking after infected patients is inadvertently touching their own faces or neck under the face shield during patient care, and removing (doffing) personal protective equipment (PPE). […] Healthcare workers should understand the following basic principles of using PPE. […] The importance of a „buddy” when inside the patient care area and during donning and doffing, to ensure safe practice cannot be overstated, together with guidance from independent monitors if available.
  • #27 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Vaccines […] The World Health Organization (WHO) has prequalified the vaccine, and several African countries have approved it for the prevention of Ebola disease caused by the Ebola virus (species Orthoebolavirus zairense). […] The vaccine is administered as a single intramuscular dose. […] Pregnant and breast-feeding women should be offered vaccination with the vaccine during an active outbreak caused by Ebola virus (species Orthoebolavirus zairense) in affected areas, in the context of rigorous research or in accordance with a compassionate use protocol, with informed consent. […] Contact tracing (e.g., family, friends, work colleagues) is essential. […] People who have been exposed to the virus within the last 21 days and who are asymptomatic need to be monitored for the duration of the incubation period in order to ensure rapid recognition of symptoms followed by immediate isolation.
  • #28 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Monitor health for 21 days after returning from an area with an ongoing outbreak and seek immediate medical care if symptoms develop. […] If infection is suspected based on initial screening, immediate isolation is warranted before any further workup is carried out. […] The highest risk facing healthcare workers when looking after infected patients is inadvertently touching their own faces or neck under the face shield during patient care, and removing (doffing) personal protective equipment (PPE). […] Healthcare workers should understand the following basic principles of using PPE. […] The importance of a „buddy” when inside the patient care area and during donning and doffing, to ensure safe practice cannot be overstated, together with guidance from independent monitors if available.
  • #29 Clinical Guidance for Ebola Disease | Ebola | CDC
    https://www.cdc.gov/ebola/hcp/clinical-guidance/index.html
    It is essential you wear proper PPE and take infection control measures while assessing a patient with suspect Ebola disease. […] Early consideration of Ebola disease in the differential diagnosis of a patient with consistent clinical and epidemiological factors is essential for providing appropriate and prompt patient care and preventing the spread of infection. […] This coordination can ensure proper patient care and appropriate precautions are taken to help prevent potential spread within the healthcare setting. […] Guidance for Personal Protective Equipment (PPE) PPE procedures for caring for VHF patients in U.S. hospitals. […] Infection Prevention and Control Recommendations for Patients in U.S. Hospitals who are Suspected or Confirmed to have Selected Viral Hemorrhagic Fevers (VHF). […] Ebola Vaccine Product Information Healthcare providers can learn about the ERVEBO Ebola vaccine product information.
  • #30 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Monitor health for 21 days after returning from an area with an ongoing outbreak and seek immediate medical care if symptoms develop. […] If infection is suspected based on initial screening, immediate isolation is warranted before any further workup is carried out. […] The highest risk facing healthcare workers when looking after infected patients is inadvertently touching their own faces or neck under the face shield during patient care, and removing (doffing) personal protective equipment (PPE). […] Healthcare workers should understand the following basic principles of using PPE. […] The importance of a „buddy” when inside the patient care area and during donning and doffing, to ensure safe practice cannot be overstated, together with guidance from independent monitors if available.
  • #31 Ebola – Control and Prevention | Occupational Safety and Health Administration
    http://www.osha.gov/ebola/control-prevention
    OSHA’s PPE Selection Matrix for Occupational Exposure to Ebola Virus provides task-based guidance to help employers select appropriate PPE for workers who may be exposed to ebolavirus. […] The general requirements of the PPE standards (29 CFR 1910.132) describe the basis for the effective selection and use of adequate PPE including protective garments. […] Employers must ensure that respiratory, head, face, and hand protection is provided for workers who may be splashed, sprayed, or spattered with blood or body fluids and from environmental surfaces where ebolavirus contamination is possible. […] Workers must be protected from exposure to harmful chemicals when cleaning and disinfecting areas contaminated with blood and/or body fluids suspected or confirmed to be infected with ebolavirus.
  • #32 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Monitor health for 21 days after returning from an area with an ongoing outbreak and seek immediate medical care if symptoms develop. […] If infection is suspected based on initial screening, immediate isolation is warranted before any further workup is carried out. […] The highest risk facing healthcare workers when looking after infected patients is inadvertently touching their own faces or neck under the face shield during patient care, and removing (doffing) personal protective equipment (PPE). […] Healthcare workers should understand the following basic principles of using PPE. […] The importance of a „buddy” when inside the patient care area and during donning and doffing, to ensure safe practice cannot be overstated, together with guidance from independent monitors if available.
  • #33
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Outbreak containment measures include safe and dignified burial of the deceased, identifying people who may have been in contact with someone infected with Ebola disease and monitoring their health for 21 days, separating the healthy from the sick to prevent further spread and providing care to confirmed patients. Maintaining good hygiene and a clean environment are also important. […] Health-care workers should always take standard precautions when caring for patients, regardless of their presumed diagnosis. These include basic hand hygiene, respiratory hygiene, use of personal protective equipment (to block splashes or other contact with infected materials), safe injection practices and safe and dignified burial practices. […] Health-care workers caring for patients with suspected or confirmed Ebola disease should apply extra infection control measures to prevent contact with the patients blood and body fluids and contaminated surfaces or materials such as clothing and bedding.
  • #34
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Outbreak containment measures include safe and dignified burial of the deceased, identifying people who may have been in contact with someone infected with Ebola disease and monitoring their health for 21 days, separating the healthy from the sick to prevent further spread and providing care to confirmed patients. Maintaining good hygiene and a clean environment are also important. […] Health-care workers should always take standard precautions when caring for patients, regardless of their presumed diagnosis. These include basic hand hygiene, respiratory hygiene, use of personal protective equipment (to block splashes or other contact with infected materials), safe injection practices and safe and dignified burial practices. […] Health-care workers caring for patients with suspected or confirmed Ebola disease should apply extra infection control measures to prevent contact with the patients blood and body fluids and contaminated surfaces or materials such as clothing and bedding.
  • #35 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Healthcare workers suspected of being infected should be isolated and treated the same as any other patient until a negative diagnosis is confirmed. […] If exposure to body fluids from a patient with suspected infection has occurred, the person should immediately wash affected skin surfaces with soap and water and irrigate mucous membranes with copious amounts of water. […] Safe burial practices are essential but are not always culturally accepted, and this continues to be a challenge. […] Post-exposure prophylaxis (PEP): […] PEP is recommended in high-risk patients (e.g., people with broken skin or mucous membrane contact with an infected patient (alive or deceased) or their body fluids, a penetrating sharps injury, or contact with contaminated gloves or clothing). […] Options to consider include passive immunotherapy with monoclonal antibodies (e.g., ZMapp, MIL77), antiviral agents (e.g., favipiravir, remdesivir, BCX4430), or vaccination (e.g., rVSV-ZEBOV) depending on specific patient circumstances. […] In addition to these interventions, psychologic support is needed for healthcare workers exposed to dangerous pathogens.
  • #36 Improving Ebola virus disease outbreak control through targeted post-exposure prophylaxis – PubMed
    https://pubmed.ncbi.nlm.nih.gov/39270687/
    Ebola virus disease kills more than half of people infected. […] Since the disease is transmitted via close human contact, identifying individuals at the highest risk of developing the disease is possible on the basis of the type of contact (correlated with viral exposure). […] Different candidates for post-exposure prophylaxis (PEP; ie, vaccines, antivirals, and monoclonal antibodies) each have their specific benefits and limitations, which we discuss in this Viewpoint. […] Approved monoclonal antibodies have been found to reduce mortality in people with Ebola virus disease. […] As monoclonal antibodies act swiftly by directly targeting the virus, they are promising candidates for targeted PEP in contacts at high risk of developing disease. […] This intervention could save lives, halt viral transmission, and, ultimately, help curtail outbreak propagation.
  • #37 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Healthcare workers suspected of being infected should be isolated and treated the same as any other patient until a negative diagnosis is confirmed. […] If exposure to body fluids from a patient with suspected infection has occurred, the person should immediately wash affected skin surfaces with soap and water and irrigate mucous membranes with copious amounts of water. […] Safe burial practices are essential but are not always culturally accepted, and this continues to be a challenge. […] Post-exposure prophylaxis (PEP): […] PEP is recommended in high-risk patients (e.g., people with broken skin or mucous membrane contact with an infected patient (alive or deceased) or their body fluids, a penetrating sharps injury, or contact with contaminated gloves or clothing). […] Options to consider include passive immunotherapy with monoclonal antibodies (e.g., ZMapp, MIL77), antiviral agents (e.g., favipiravir, remdesivir, BCX4430), or vaccination (e.g., rVSV-ZEBOV) depending on specific patient circumstances. […] In addition to these interventions, psychologic support is needed for healthcare workers exposed to dangerous pathogens.
  • #38 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Healthcare workers suspected of being infected should be isolated and treated the same as any other patient until a negative diagnosis is confirmed. […] If exposure to body fluids from a patient with suspected infection has occurred, the person should immediately wash affected skin surfaces with soap and water and irrigate mucous membranes with copious amounts of water. […] Safe burial practices are essential but are not always culturally accepted, and this continues to be a challenge. […] Post-exposure prophylaxis (PEP): […] PEP is recommended in high-risk patients (e.g., people with broken skin or mucous membrane contact with an infected patient (alive or deceased) or their body fluids, a penetrating sharps injury, or contact with contaminated gloves or clothing). […] Options to consider include passive immunotherapy with monoclonal antibodies (e.g., ZMapp, MIL77), antiviral agents (e.g., favipiravir, remdesivir, BCX4430), or vaccination (e.g., rVSV-ZEBOV) depending on specific patient circumstances. […] In addition to these interventions, psychologic support is needed for healthcare workers exposed to dangerous pathogens.
  • #39 Improving Ebola virus disease outbreak control through targeted post-exposure prophylaxis – PubMed
    https://pubmed.ncbi.nlm.nih.gov/39270687/
    Ebola virus disease kills more than half of people infected. […] Since the disease is transmitted via close human contact, identifying individuals at the highest risk of developing the disease is possible on the basis of the type of contact (correlated with viral exposure). […] Different candidates for post-exposure prophylaxis (PEP; ie, vaccines, antivirals, and monoclonal antibodies) each have their specific benefits and limitations, which we discuss in this Viewpoint. […] Approved monoclonal antibodies have been found to reduce mortality in people with Ebola virus disease. […] As monoclonal antibodies act swiftly by directly targeting the virus, they are promising candidates for targeted PEP in contacts at high risk of developing disease. […] This intervention could save lives, halt viral transmission, and, ultimately, help curtail outbreak propagation.
  • #40 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Healthcare workers suspected of being infected should be isolated and treated the same as any other patient until a negative diagnosis is confirmed. […] If exposure to body fluids from a patient with suspected infection has occurred, the person should immediately wash affected skin surfaces with soap and water and irrigate mucous membranes with copious amounts of water. […] Safe burial practices are essential but are not always culturally accepted, and this continues to be a challenge. […] Post-exposure prophylaxis (PEP): […] PEP is recommended in high-risk patients (e.g., people with broken skin or mucous membrane contact with an infected patient (alive or deceased) or their body fluids, a penetrating sharps injury, or contact with contaminated gloves or clothing). […] Options to consider include passive immunotherapy with monoclonal antibodies (e.g., ZMapp, MIL77), antiviral agents (e.g., favipiravir, remdesivir, BCX4430), or vaccination (e.g., rVSV-ZEBOV) depending on specific patient circumstances. […] In addition to these interventions, psychologic support is needed for healthcare workers exposed to dangerous pathogens.
  • #41 Postexposure prophylaxis may prevent Ebola disease development | MDedge
    https://www.mdedge.com/familypracticenews/article/102171/infectious-diseases/postexposure-prophylaxis-may-prevent-ebola
    Postexposure prophylaxis may prevent Ebola disease development […] A small group of health care workers at intermediate or high risk of developing Ebola virus disease after exposure to the virus did not develop the disease after being treated with postexposure prophylaxis, according to Dr. Michael Jacobs and his associates. […] Of eight health care workers evacuated to the United Kingdom between January and March 2015 and assessed using an Ebola risk calculator, four were deemed to be at intermediate or high risk for developing Ebola virus disease (EVD) and were started on postexposure prophylaxis (PEP) using oral favipiravir over 10 days. […] In addition, two of the four also were treated with monoclonal antibodies to Ebola glycoproteins. […] The favipiravir, administered in high dosages, was tolerated well by the four patients, the investigators reported in Lancet Infectious Diseases.
  • #42 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Healthcare workers suspected of being infected should be isolated and treated the same as any other patient until a negative diagnosis is confirmed. […] If exposure to body fluids from a patient with suspected infection has occurred, the person should immediately wash affected skin surfaces with soap and water and irrigate mucous membranes with copious amounts of water. […] Safe burial practices are essential but are not always culturally accepted, and this continues to be a challenge. […] Post-exposure prophylaxis (PEP): […] PEP is recommended in high-risk patients (e.g., people with broken skin or mucous membrane contact with an infected patient (alive or deceased) or their body fluids, a penetrating sharps injury, or contact with contaminated gloves or clothing). […] Options to consider include passive immunotherapy with monoclonal antibodies (e.g., ZMapp, MIL77), antiviral agents (e.g., favipiravir, remdesivir, BCX4430), or vaccination (e.g., rVSV-ZEBOV) depending on specific patient circumstances. […] In addition to these interventions, psychologic support is needed for healthcare workers exposed to dangerous pathogens.
  • #43 Ebola disease – Prevention | BMJ Best Practice US
    https://bestpractice.bmj.com/topics/en-us/1210/prevention
    Healthcare workers suspected of being infected should be isolated and treated the same as any other patient until a negative diagnosis is confirmed. […] If exposure to body fluids from a patient with suspected infection has occurred, the person should immediately wash affected skin surfaces with soap and water and irrigate mucous membranes with copious amounts of water. […] Safe burial practices are essential but are not always culturally accepted, and this continues to be a challenge. […] Post-exposure prophylaxis (PEP): […] PEP is recommended in high-risk patients (e.g., people with broken skin or mucous membrane contact with an infected patient (alive or deceased) or their body fluids, a penetrating sharps injury, or contact with contaminated gloves or clothing). […] Options to consider include passive immunotherapy with monoclonal antibodies (e.g., ZMapp, MIL77), antiviral agents (e.g., favipiravir, remdesivir, BCX4430), or vaccination (e.g., rVSV-ZEBOV) depending on specific patient circumstances. […] In addition to these interventions, psychologic support is needed for healthcare workers exposed to dangerous pathogens.
  • #44 Postexposure prophylaxis may prevent Ebola disease development | MDedge
    https://www.mdedge.com/familypracticenews/article/102171/infectious-diseases/postexposure-prophylaxis-may-prevent-ebola
    Postexposure prophylaxis may prevent Ebola disease development […] A small group of health care workers at intermediate or high risk of developing Ebola virus disease after exposure to the virus did not develop the disease after being treated with postexposure prophylaxis, according to Dr. Michael Jacobs and his associates. […] Of eight health care workers evacuated to the United Kingdom between January and March 2015 and assessed using an Ebola risk calculator, four were deemed to be at intermediate or high risk for developing Ebola virus disease (EVD) and were started on postexposure prophylaxis (PEP) using oral favipiravir over 10 days. […] In addition, two of the four also were treated with monoclonal antibodies to Ebola glycoproteins. […] The favipiravir, administered in high dosages, was tolerated well by the four patients, the investigators reported in Lancet Infectious Diseases.
  • #45 Postexposure prophylaxis may prevent Ebola disease development | MDedge
    https://www.mdedge.com/familypracticenews/article/102171/infectious-diseases/postexposure-prophylaxis-may-prevent-ebola
    The second half of the eight-person study group had a low risk of EVD after assessment, and patients in this group were watched carefully, receiving no other form of treatment. No EVD developed in this low-risk group. […] It cannot be known “whether or not PEP prevented the onset of Ebola virus disease in any of these individuals. […] However, two individuals had very high risk of Ebola virus transmission, and these are the first reported cases of transcutaneous, hollow-bore needlestick injuries contaminated with fresh blood that have not resulted in Ebola virus transmission,” noted Dr. Jacobs of the department of infection at Royal Free London NHS Foundation Trust and his associates. […] In a related comment, Dr. Mark J. Mulligan and Dr. Paul N. Siebert said, “A needed next step is the development of a consensus risk determination algorithm devised by an expert panel, drawing on all available evidence, endorsed by health organizations, and disseminated to the field.
  • #46
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    To mitigate the risk of this transmission, a semen testing programme should be implemented to: […] offer counselling to male survivors and their sexual partners to inform them of the potential risk and support them adhering to safer sex practices (including condom provision and good hand and personal hygiene); […] offer monthly semen testing until they have had two consecutive negative test results; and […] after two consecutive negative tests, survivors can safely resume normal sexual practices with minimized risk of virus transmission. […] In the absence of a semen testing programme, male survivors should follow safer sex practices for 12 months. […] Survivor care programmes should encompass care for pregnant and breastfeeding women after their recovery.
  • #47 Factsheet about Ebola disease
    https://www.ecdc.europa.eu/en/infectious-disease-topics/ebola-virus-disease/facts/factsheet-about-ebola-disease
    For Zaire ebolavirus transmission by sexual contact has been documented and the World Health Organization (WHO) recommends that male survivors practise safe sex for at least 12 months after clinical recovery, unless their semen has tested negative on two separate occasions. […] Individuals with evidence of Ebola disease should not donate blood and other substances of human origin (SoHO). Potentially exposed individuals (those being monitored, asymptomatic travellers or residents returning from an Ebola disease-affected area) should defer donation of SoHO for eight weeks after return or from the beginning of the monitoring period. […] Significant developments have been made for the prevention of Ebola disease (Zaire ebolavirus), with two vaccines now licensed for use in several countries.
  • #48
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    To mitigate the risk of this transmission, a semen testing programme should be implemented to: […] offer counselling to male survivors and their sexual partners to inform them of the potential risk and support them adhering to safer sex practices (including condom provision and good hand and personal hygiene); […] offer monthly semen testing until they have had two consecutive negative test results; and […] after two consecutive negative tests, survivors can safely resume normal sexual practices with minimized risk of virus transmission. […] In the absence of a semen testing programme, male survivors should follow safer sex practices for 12 months. […] Survivor care programmes should encompass care for pregnant and breastfeeding women after their recovery.
  • #49
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    To mitigate the risk of this transmission, a semen testing programme should be implemented to: […] offer counselling to male survivors and their sexual partners to inform them of the potential risk and support them adhering to safer sex practices (including condom provision and good hand and personal hygiene); […] offer monthly semen testing until they have had two consecutive negative test results; and […] after two consecutive negative tests, survivors can safely resume normal sexual practices with minimized risk of virus transmission. […] In the absence of a semen testing programme, male survivors should follow safer sex practices for 12 months. […] Survivor care programmes should encompass care for pregnant and breastfeeding women after their recovery.
  • #50
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    To mitigate the risk of this transmission, a semen testing programme should be implemented to: […] offer counselling to male survivors and their sexual partners to inform them of the potential risk and support them adhering to safer sex practices (including condom provision and good hand and personal hygiene); […] offer monthly semen testing until they have had two consecutive negative test results; and […] after two consecutive negative tests, survivors can safely resume normal sexual practices with minimized risk of virus transmission. […] In the absence of a semen testing programme, male survivors should follow safer sex practices for 12 months. […] Survivor care programmes should encompass care for pregnant and breastfeeding women after their recovery.
  • #51
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    To mitigate the risk of this transmission, a semen testing programme should be implemented to: […] offer counselling to male survivors and their sexual partners to inform them of the potential risk and support them adhering to safer sex practices (including condom provision and good hand and personal hygiene); […] offer monthly semen testing until they have had two consecutive negative test results; and […] after two consecutive negative tests, survivors can safely resume normal sexual practices with minimized risk of virus transmission. […] In the absence of a semen testing programme, male survivors should follow safer sex practices for 12 months. […] Survivor care programmes should encompass care for pregnant and breastfeeding women after their recovery.
  • #52 Factsheet about Ebola disease
    https://www.ecdc.europa.eu/en/infectious-disease-topics/ebola-virus-disease/facts/factsheet-about-ebola-disease
    For Zaire ebolavirus transmission by sexual contact has been documented and the World Health Organization (WHO) recommends that male survivors practise safe sex for at least 12 months after clinical recovery, unless their semen has tested negative on two separate occasions. […] Individuals with evidence of Ebola disease should not donate blood and other substances of human origin (SoHO). Potentially exposed individuals (those being monitored, asymptomatic travellers or residents returning from an Ebola disease-affected area) should defer donation of SoHO for eight weeks after return or from the beginning of the monitoring period. […] Significant developments have been made for the prevention of Ebola disease (Zaire ebolavirus), with two vaccines now licensed for use in several countries.
  • #53
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Community engagement is key to successfully controlling any outbreak. Outbreak control relies on using a range of interventions, such as clinical care, surveillance and contact tracing, laboratory services, infection prevention and control in health facilities, safe and dignified burials, vaccination (only for Ebola virus disease) and social mobilization. […] Raising awareness of risk factors and protective measures that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors: […] Reduce the risk of human-to-human transmission arising from direct or close contact with infected people, particularly with their body fluids. Close physical contact with Ebola patients should be avoided. Patients should be isolated in a designated treatment center for early care and to avoid transmission at home.
  • #54 Factsheet about Ebola disease
    https://www.ecdc.europa.eu/en/infectious-disease-topics/ebola-virus-disease/facts/factsheet-about-ebola-disease
    Ebola disease is not an airborne disease and is generally not considered to be contagious before the onset of symptoms. Transmission requires direct contact with the organs, blood, secretions or other bodily fluids of infected people/animals or their dead bodies. Therefore, the risk of infection is considered to be very low if strict infection prevention and control precautions are followed. […] The risk of infection can be significantly reduced through the appropriate use of infection control precautions and adequate barrier protection. This is especially important when performing invasive procedures. […] The goal of Ebola disease outbreak control is to interrupt direct human-to-human transmission. Outbreak control activities are based on the early identification and systematic rapid isolation of cases, through appropriate infection prevention and control (IPC) measures, timely and comprehensive contact tracing, disinfection of infectious materials, and use of personal protective equipment.
  • #55
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Community engagement is key to successfully controlling any outbreak. Outbreak control relies on using a range of interventions, such as clinical care, surveillance and contact tracing, laboratory services, infection prevention and control in health facilities, safe and dignified burials, vaccination (only for Ebola virus disease) and social mobilization. […] Raising awareness of risk factors and protective measures that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors: […] Reduce the risk of human-to-human transmission arising from direct or close contact with infected people, particularly with their body fluids. Close physical contact with Ebola patients should be avoided. Patients should be isolated in a designated treatment center for early care and to avoid transmission at home.
  • #56 Ebola Virus Disease – PAHO/WHO | Pan American Health Organization
    https://www.paho.org/en/topics/ebola-virus-disease
    Ebola virus disease (EVD), formerly known as Ebola hemorrhagic fever, is a rare but severe, often fatal illness in humans. […] Community engagement is key to successfully controlling outbreaks. […] Good outbreak control relies on applying a package of interventions, namely case management, infection prevention and control practices, surveillance and contact tracing, a good laboratory service, safe and dignified burials and social mobilization. […] Vaccines to protect against Ebola have been developed and have been used to help control the spread of Ebola outbreaks in Guinea and in the Democratic Republic of the Congo (DRC). […] Pregnant and breastfeeding women with Ebola should be offered early supportive care. Likewise vaccine prevention and experimental treatment should be offered under the same conditions as for non-pregnant population.
  • #57
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Community engagement is key to successfully controlling any outbreak. Outbreak control relies on using a range of interventions, such as clinical care, surveillance and contact tracing, laboratory services, infection prevention and control in health facilities, safe and dignified burials, vaccination (only for Ebola virus disease) and social mobilization. […] Raising awareness of risk factors and protective measures that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors: […] Reduce the risk of human-to-human transmission arising from direct or close contact with infected people, particularly with their body fluids. Close physical contact with Ebola patients should be avoided. Patients should be isolated in a designated treatment center for early care and to avoid transmission at home.
  • #58
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Community engagement is key to successfully controlling any outbreak. Outbreak control relies on using a range of interventions, such as clinical care, surveillance and contact tracing, laboratory services, infection prevention and control in health facilities, safe and dignified burials, vaccination (only for Ebola virus disease) and social mobilization. […] Raising awareness of risk factors and protective measures that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors: […] Reduce the risk of human-to-human transmission arising from direct or close contact with infected people, particularly with their body fluids. Close physical contact with Ebola patients should be avoided. Patients should be isolated in a designated treatment center for early care and to avoid transmission at home.
  • #59
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Outbreak containment measures include safe and dignified burial of the deceased, identifying people who may have been in contact with someone infected with Ebola disease and monitoring their health for 21 days, separating the healthy from the sick to prevent further spread and providing care to confirmed patients. Maintaining good hygiene and a clean environment are also important. […] Health-care workers should always take standard precautions when caring for patients, regardless of their presumed diagnosis. These include basic hand hygiene, respiratory hygiene, use of personal protective equipment (to block splashes or other contact with infected materials), safe injection practices and safe and dignified burial practices. […] Health-care workers caring for patients with suspected or confirmed Ebola disease should apply extra infection control measures to prevent contact with the patients blood and body fluids and contaminated surfaces or materials such as clothing and bedding.
  • #60
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Community engagement is key to successfully controlling any outbreak. Outbreak control relies on using a range of interventions, such as clinical care, surveillance and contact tracing, laboratory services, infection prevention and control in health facilities, safe and dignified burials, vaccination (only for Ebola virus disease) and social mobilization. […] Raising awareness of risk factors and protective measures that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors: […] Reduce the risk of human-to-human transmission arising from direct or close contact with infected people, particularly with their body fluids. Close physical contact with Ebola patients should be avoided. Patients should be isolated in a designated treatment center for early care and to avoid transmission at home.
  • #61
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Community engagement is key to successfully controlling any outbreak. Outbreak control relies on using a range of interventions, such as clinical care, surveillance and contact tracing, laboratory services, infection prevention and control in health facilities, safe and dignified burials, vaccination (only for Ebola virus disease) and social mobilization. […] Raising awareness of risk factors and protective measures that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors: […] Reduce the risk of human-to-human transmission arising from direct or close contact with infected people, particularly with their body fluids. Close physical contact with Ebola patients should be avoided. Patients should be isolated in a designated treatment center for early care and to avoid transmission at home.
  • #62 Infection prevention and control measures for Ebola disease in acute care settings – Canada.ca
    https://www.canada.ca/en/public-health/services/diseases/ebola/health-professionals-ebola/infection-prevention-control-measures-healthcare-settings.html
    This guidance document updates the previous Infection Prevention and Control Measures for Ebola Virus Disease (EVD) in Healthcare Settings (August 28, 2019). This version has updated recommendations for: […] The purpose of this document is to provide guidance on the minimum level of IPC measures in healthcare settings in the event that a person under investigation for EBOD or patient with EBOD is identified within a Canadian healthcare facility. […] Public health case management relies on early identification of EBOD cases, individual isolation and care, diligent contact tracing, appropriate IPC measures, and safe burial. […] While elimination may not be possible, to mitigate risk of transmission in healthcare facilities, systems and protocols should be in place to limit the care of persons under investigation for EBOD or confirmed patients with EBOD to designated locations within a hospital (e.g., ER, ICU), or designated hospitals with dedicated personnel.
  • #63
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Community engagement is key to successfully controlling any outbreak. Outbreak control relies on using a range of interventions, such as clinical care, surveillance and contact tracing, laboratory services, infection prevention and control in health facilities, safe and dignified burials, vaccination (only for Ebola virus disease) and social mobilization. […] Raising awareness of risk factors and protective measures that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors: […] Reduce the risk of human-to-human transmission arising from direct or close contact with infected people, particularly with their body fluids. Close physical contact with Ebola patients should be avoided. Patients should be isolated in a designated treatment center for early care and to avoid transmission at home.
  • #64 Ebola virus disease in children: epidemiology, pathogenesis, management, and prevention | Pediatric Research
    https://www.nature.com/articles/s41390-023-02873-y
    Interruption of community and nosocomial transmission is achieved through educational and sociological measures, isolation of suspected or confirmed cases for care, strict infection control protocols, contact tracing, and vaccination. […] Safe and dignified burials help to prevent transmission while also emphasizing inclusion of family members and encouraging religious rites. […] The structure of ETUs necessarily restricts the presence of uninfected caregivers, which can create a setting that is not safe or comforting to children. Adaptations to this structure, including recruiting survivors to help with the care of children, can help to address these difficulties. […] Vaccines to protect against EVD have emerged rapidly since 2013. Currently, two regimens are being used to provide protection against EBOV: the Merck rVSV-ZEBOV regimen (sold as Ervebo) and the Janssen Ad26.ZEBOV/MVA-BN-Filo regimen (sold as Zabdeno/Mvabea).
  • #65
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Community engagement is key to successfully controlling any outbreak. Outbreak control relies on using a range of interventions, such as clinical care, surveillance and contact tracing, laboratory services, infection prevention and control in health facilities, safe and dignified burials, vaccination (only for Ebola virus disease) and social mobilization. […] Raising awareness of risk factors and protective measures that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors: […] Reduce the risk of human-to-human transmission arising from direct or close contact with infected people, particularly with their body fluids. Close physical contact with Ebola patients should be avoided. Patients should be isolated in a designated treatment center for early care and to avoid transmission at home.
  • #66
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Outbreak containment measures include safe and dignified burial of the deceased, identifying people who may have been in contact with someone infected with Ebola disease and monitoring their health for 21 days, separating the healthy from the sick to prevent further spread and providing care to confirmed patients. Maintaining good hygiene and a clean environment are also important. […] Health-care workers should always take standard precautions when caring for patients, regardless of their presumed diagnosis. These include basic hand hygiene, respiratory hygiene, use of personal protective equipment (to block splashes or other contact with infected materials), safe injection practices and safe and dignified burial practices. […] Health-care workers caring for patients with suspected or confirmed Ebola disease should apply extra infection control measures to prevent contact with the patients blood and body fluids and contaminated surfaces or materials such as clothing and bedding.
  • #67 Clinical Guidance for Ebola Disease | Ebola | CDC
    https://www.cdc.gov/ebola/hcp/clinical-guidance/index.html
    It is essential you wear proper PPE and take infection control measures while assessing a patient with suspect Ebola disease. […] Early consideration of Ebola disease in the differential diagnosis of a patient with consistent clinical and epidemiological factors is essential for providing appropriate and prompt patient care and preventing the spread of infection. […] This coordination can ensure proper patient care and appropriate precautions are taken to help prevent potential spread within the healthcare setting. […] Guidance for Personal Protective Equipment (PPE) PPE procedures for caring for VHF patients in U.S. hospitals. […] Infection Prevention and Control Recommendations for Patients in U.S. Hospitals who are Suspected or Confirmed to have Selected Viral Hemorrhagic Fevers (VHF). […] Ebola Vaccine Product Information Healthcare providers can learn about the ERVEBO Ebola vaccine product information.
  • #68 Ebola – Control and Prevention | Occupational Safety and Health Administration
    http://www.osha.gov/ebola/control-prevention
    Most workers in the U.S. are very unlikely to encounter ebolavirus or individuals with EVD. However, exposure to the virus or someone with EVD may be more likely in certain sectors, including the healthcare, mortuary/death care, and airline servicing industries. Workers who interact with people, animals, goods, and equipment arriving in the U.S. from foreign countries with current EVD outbreaks are at the greatest risk for exposure. […] Precautionary measures for preventing exposure to ebolavirus depend on the type of work, potential for ebolavirus contamination of the work environment, and what is known about other potential exposure hazards. […] Employers are responsible for ensuring their workers are protected from exposures to recognized bloodborne pathogens, including ebolaviruses, and related hazards.
  • #69 Ebola – Control and Prevention | Occupational Safety and Health Administration
    http://www.osha.gov/ebola/control-prevention
    Conduct hazard assessments for workers whose jobs may increase the likelihood of exposure to ebolavirus, with consideration given to potential sources of infection, including risks and routes of exposure associated with work procedures and job tasks. […] Select appropriate controls, including engineering controls, administrative controls, safe work practices, and personal protective equipment (PPE), based on the results of the hazard analysis. […] Offer the option for vaccination to eligible workers whose jobs put them at risk for exposure to EVD. […] Early identification and isolation of potentially infectious people is a key step in preventing the spread of EVD, particularly for workers who may be exposed on the job to a person with the virus. […] When engineering or administrative and work practice controls are insufficient to prevent employee exposure to the ebolavirus, or before engineering controls can be implemented, employers must provide appropriate PPE for workers.
  • #70 For Healthcare Providers – Ebola Virus Disease and Marburg Virus Disease | Washington State Department of Health
    https://doh.wa.gov/emergencies/be-prepared-be-safe/diseases/ebola-virus-disease-and-marburg-virus-disease/healthcare-providers
    Recommendations for infection prevention and control precautions for MVD are the same as for EVD in U.S. healthcare settings. […] If a person has a possible exposure to EVD or MVD and symptoms, follow the identify, isolate, and inform strategy to reduce exposure in your health care facility. […] The person should immediately be placed in a private room with an in-room bathroom or covered bedside commode. […] Minimize the number of personnel in contact with the patient and maintain a log of all people entering the patient’s room. […] Perform only necessary tests and procedures and avoid aerosol-generating procedures. […] Inform your local health jurisdiction and your facilitys infection control program. […] Follow CDC environmental infection control guidance for cleaning and disinfection of the patient room/area. […] Ensure that your facility has correct and sufficient PPE to use for a person confirmed as or under investigation for viral hemorrhagic fever who is clinically unstable or is bleeding, vomiting, or has diarrhea.
  • #71 Infection prevention and control measures for Ebola disease in acute care settings – Canada.ca
    https://www.canada.ca/en/public-health/services/diseases/ebola/health-professionals-ebola/infection-prevention-control-measures-healthcare-settings.html
    Each healthcare organization should develop comprehensive policies and procedures for putting on and removing personal protective equipment. […] To be effective in preventing transmission of EBOD and/or detecting cases of EBOD, administrative controls should be applied from the first encounter with a PUI and continue until the patient leaves the healthcare setting, is no longer infectious, or is deceased (note, proper post-mortem care is required). […] Personal Protective Equipment (PPE) refers to all personal equipment and clothing recommended by the employer for use by the HCW. […] Healthcare organizations need to ensure an adequate supply of appropriate PPE to protect HCWs and that their HCWs are adept in the application, use and removal of their PPE. […] The ORA will characterize the organization’s patient population, level and intensity of health care provided and resources available, including the various skilled workers required to provide the necessary care.
  • #72 For Healthcare Providers – Ebola Virus Disease and Marburg Virus Disease | Washington State Department of Health
    https://doh.wa.gov/emergencies/be-prepared-be-safe/diseases/ebola-virus-disease-and-marburg-virus-disease/healthcare-providers
    Recommendations for infection prevention and control precautions for MVD are the same as for EVD in U.S. healthcare settings. […] If a person has a possible exposure to EVD or MVD and symptoms, follow the identify, isolate, and inform strategy to reduce exposure in your health care facility. […] The person should immediately be placed in a private room with an in-room bathroom or covered bedside commode. […] Minimize the number of personnel in contact with the patient and maintain a log of all people entering the patient’s room. […] Perform only necessary tests and procedures and avoid aerosol-generating procedures. […] Inform your local health jurisdiction and your facilitys infection control program. […] Follow CDC environmental infection control guidance for cleaning and disinfection of the patient room/area. […] Ensure that your facility has correct and sufficient PPE to use for a person confirmed as or under investigation for viral hemorrhagic fever who is clinically unstable or is bleeding, vomiting, or has diarrhea.
  • #73 For Healthcare Providers – Ebola Virus Disease and Marburg Virus Disease | Washington State Department of Health
    https://doh.wa.gov/emergencies/be-prepared-be-safe/diseases/ebola-virus-disease-and-marburg-virus-disease/healthcare-providers
    Recommendations for infection prevention and control precautions for MVD are the same as for EVD in U.S. healthcare settings. […] If a person has a possible exposure to EVD or MVD and symptoms, follow the identify, isolate, and inform strategy to reduce exposure in your health care facility. […] The person should immediately be placed in a private room with an in-room bathroom or covered bedside commode. […] Minimize the number of personnel in contact with the patient and maintain a log of all people entering the patient’s room. […] Perform only necessary tests and procedures and avoid aerosol-generating procedures. […] Inform your local health jurisdiction and your facilitys infection control program. […] Follow CDC environmental infection control guidance for cleaning and disinfection of the patient room/area. […] Ensure that your facility has correct and sufficient PPE to use for a person confirmed as or under investigation for viral hemorrhagic fever who is clinically unstable or is bleeding, vomiting, or has diarrhea.
  • #74 For Healthcare Providers – Ebola Virus Disease and Marburg Virus Disease | Washington State Department of Health
    https://doh.wa.gov/emergencies/be-prepared-be-safe/diseases/ebola-virus-disease-and-marburg-virus-disease/healthcare-providers
    Recommendations for infection prevention and control precautions for MVD are the same as for EVD in U.S. healthcare settings. […] If a person has a possible exposure to EVD or MVD and symptoms, follow the identify, isolate, and inform strategy to reduce exposure in your health care facility. […] The person should immediately be placed in a private room with an in-room bathroom or covered bedside commode. […] Minimize the number of personnel in contact with the patient and maintain a log of all people entering the patient’s room. […] Perform only necessary tests and procedures and avoid aerosol-generating procedures. […] Inform your local health jurisdiction and your facilitys infection control program. […] Follow CDC environmental infection control guidance for cleaning and disinfection of the patient room/area. […] Ensure that your facility has correct and sufficient PPE to use for a person confirmed as or under investigation for viral hemorrhagic fever who is clinically unstable or is bleeding, vomiting, or has diarrhea.
  • #75 Ebola – Control and Prevention | Occupational Safety and Health Administration
    http://www.osha.gov/ebola/control-prevention
    OSHA’s PPE Selection Matrix for Occupational Exposure to Ebola Virus provides task-based guidance to help employers select appropriate PPE for workers who may be exposed to ebolavirus. […] The general requirements of the PPE standards (29 CFR 1910.132) describe the basis for the effective selection and use of adequate PPE including protective garments. […] Employers must ensure that respiratory, head, face, and hand protection is provided for workers who may be splashed, sprayed, or spattered with blood or body fluids and from environmental surfaces where ebolavirus contamination is possible. […] Workers must be protected from exposure to harmful chemicals when cleaning and disinfecting areas contaminated with blood and/or body fluids suspected or confirmed to be infected with ebolavirus.
  • #76 Ebola – Control and Prevention | Occupational Safety and Health Administration
    http://www.osha.gov/ebola/control-prevention
    Disinfectants proven effective against ebolavirus are described on the U.S. Environmental Protection Agency’s (EPA) List L: Disinfectants for Use Against Ebola Virus and List Q: Disinfectants for Emerging Viral Pathogens (EVP). […] Prevention of the most commonly occurring ebolavirus, Zaire ebolavirus (EBOV), is possible with the Food and Drug Administration (FDA)-approved vaccine, rVSV-ZEBOV (Ervebo®). […] In addition, the Advisory Committee on Immunization Practices recommends pre-exposure prophylaxis vaccination with Ervebo® for adults 18 years of age or older in the U.S. population who are at potential occupational risk of exposure to EBOV. […] All workers with potential exposure to ebolaviruses should take the following precautions: […] If you believe that you may have been exposed to ebolavirus, tell your employer, and monitor your health for 21 days.
  • #77 Ebola – Control and Prevention | Occupational Safety and Health Administration
    http://www.osha.gov/ebola/control-prevention
    OSHA’s PPE Selection Matrix for Occupational Exposure to Ebola Virus provides task-based guidance to help employers select appropriate PPE for workers who may be exposed to ebolavirus. […] The general requirements of the PPE standards (29 CFR 1910.132) describe the basis for the effective selection and use of adequate PPE including protective garments. […] Employers must ensure that respiratory, head, face, and hand protection is provided for workers who may be splashed, sprayed, or spattered with blood or body fluids and from environmental surfaces where ebolavirus contamination is possible. […] Workers must be protected from exposure to harmful chemicals when cleaning and disinfecting areas contaminated with blood and/or body fluids suspected or confirmed to be infected with ebolavirus.
  • #78 Ebola – Control and Prevention | Occupational Safety and Health Administration
    http://www.osha.gov/ebola/control-prevention
    Disinfectants proven effective against ebolavirus are described on the U.S. Environmental Protection Agency’s (EPA) List L: Disinfectants for Use Against Ebola Virus and List Q: Disinfectants for Emerging Viral Pathogens (EVP). […] Prevention of the most commonly occurring ebolavirus, Zaire ebolavirus (EBOV), is possible with the Food and Drug Administration (FDA)-approved vaccine, rVSV-ZEBOV (Ervebo®). […] In addition, the Advisory Committee on Immunization Practices recommends pre-exposure prophylaxis vaccination with Ervebo® for adults 18 years of age or older in the U.S. population who are at potential occupational risk of exposure to EBOV. […] All workers with potential exposure to ebolaviruses should take the following precautions: […] If you believe that you may have been exposed to ebolavirus, tell your employer, and monitor your health for 21 days.
  • #79 For Healthcare Providers – Ebola Virus Disease and Marburg Virus Disease | Washington State Department of Health
    https://doh.wa.gov/emergencies/be-prepared-be-safe/diseases/ebola-virus-disease-and-marburg-virus-disease/healthcare-providers
    Recommendations for infection prevention and control precautions for MVD are the same as for EVD in U.S. healthcare settings. […] If a person has a possible exposure to EVD or MVD and symptoms, follow the identify, isolate, and inform strategy to reduce exposure in your health care facility. […] The person should immediately be placed in a private room with an in-room bathroom or covered bedside commode. […] Minimize the number of personnel in contact with the patient and maintain a log of all people entering the patient’s room. […] Perform only necessary tests and procedures and avoid aerosol-generating procedures. […] Inform your local health jurisdiction and your facilitys infection control program. […] Follow CDC environmental infection control guidance for cleaning and disinfection of the patient room/area. […] Ensure that your facility has correct and sufficient PPE to use for a person confirmed as or under investigation for viral hemorrhagic fever who is clinically unstable or is bleeding, vomiting, or has diarrhea.
  • #80 What Is Ebola? Symptoms, Causes, Diagnosis, Treatment, and Prevention
    https://www.everydayhealth.com/ebola/guide/
    Measures that may prevent the spread of Ebola include the following: […] Avoid visiting areas with known outbreaks. […] Isolate infected patients from anyone who doesn’t have Ebola. […] Have healthcare workers wear protective gear, including gloves, masks, goggles, gowns, and other clothing, while caring for Ebola patients. […] Decontaminate or destroy any surfaces or materials a patient has had contact with, including syringes, needles, and other medical equipment. […] Wash hands frequently with soap and water or use an alcohol-based sanitizer. […] Avoid handling or eating bushmeat. […] Monitor anyone who comes into contact with an Ebola patient. […] The Ebola virus can survive for several hours on dry surfaces, like doorknobs and countertops. […] And it can live for up to several days at room temperature in body fluids.
  • #81 What Is Ebola? Symptoms, Causes, Diagnosis, Treatment, and Prevention
    https://www.everydayhealth.com/ebola/guide/
    The virus can be killed using a U.S. Environmental Protection Agency (EPA) registered hospital disinfectant with a label for a nonenveloped virus. […] Spotting cases of Ebola early on may be the key to stopping outbreaks. […] Contact tracing is one tactic that experts use to identify people who have been exposed to someone with Ebola. […] These contacts are watched for signs of Ebola for 21 days from the last day they were around the infected patient. […] If a contact develops a fever or other classic symptoms of Ebola, they will be immediately isolated and tested for the virus. […] The WHO considers an Ebola outbreak to be over after 42 days (or two incubation periods) have passed without any new infections, according to the CDC.
  • #82 Ebola – Control and Prevention | Occupational Safety and Health Administration
    http://www.osha.gov/ebola/control-prevention
    OSHA’s PPE Selection Matrix for Occupational Exposure to Ebola Virus provides task-based guidance to help employers select appropriate PPE for workers who may be exposed to ebolavirus. […] The general requirements of the PPE standards (29 CFR 1910.132) describe the basis for the effective selection and use of adequate PPE including protective garments. […] Employers must ensure that respiratory, head, face, and hand protection is provided for workers who may be splashed, sprayed, or spattered with blood or body fluids and from environmental surfaces where ebolavirus contamination is possible. […] Workers must be protected from exposure to harmful chemicals when cleaning and disinfecting areas contaminated with blood and/or body fluids suspected or confirmed to be infected with ebolavirus.
  • #83 Ebola Virus Disease
    https://oklahoma.gov/health/health-education/acute-disease-service/disease-information/ebola-virus-disease.html
    Avoid contact with animals or with raw meat. […] Avoid hospitals where Ebola patients are being treated. The U.S. Embassy or consulate is often able to provide advice on facilities that are suitable for your needs. […] People who have traveled to a country where Ebola is being spread should seek medical care immediately if they develop fever, headache, achiness, diarrhea, vomiting, stomach pain, rash or red eyes within 21 days of traveling. Call your provider ahead of time to let them know of your symptoms and travel history to a place where Ebola is being spread.
  • #84 Ebola – Control and Prevention | Occupational Safety and Health Administration
    http://www.osha.gov/ebola/control-prevention
    OSHA’s PPE Selection Matrix for Occupational Exposure to Ebola Virus provides task-based guidance to help employers select appropriate PPE for workers who may be exposed to ebolavirus. […] The general requirements of the PPE standards (29 CFR 1910.132) describe the basis for the effective selection and use of adequate PPE including protective garments. […] Employers must ensure that respiratory, head, face, and hand protection is provided for workers who may be splashed, sprayed, or spattered with blood or body fluids and from environmental surfaces where ebolavirus contamination is possible. […] Workers must be protected from exposure to harmful chemicals when cleaning and disinfecting areas contaminated with blood and/or body fluids suspected or confirmed to be infected with ebolavirus.
  • #85 Ebola – Control and Prevention | Occupational Safety and Health Administration
    http://www.osha.gov/ebola/control-prevention
    Conduct hazard assessments for workers whose jobs may increase the likelihood of exposure to ebolavirus, with consideration given to potential sources of infection, including risks and routes of exposure associated with work procedures and job tasks. […] Select appropriate controls, including engineering controls, administrative controls, safe work practices, and personal protective equipment (PPE), based on the results of the hazard analysis. […] Offer the option for vaccination to eligible workers whose jobs put them at risk for exposure to EVD. […] Early identification and isolation of potentially infectious people is a key step in preventing the spread of EVD, particularly for workers who may be exposed on the job to a person with the virus. […] When engineering or administrative and work practice controls are insufficient to prevent employee exposure to the ebolavirus, or before engineering controls can be implemented, employers must provide appropriate PPE for workers.
  • #86 EMS Strategies for Ebola | NETEC
    https://netec.org/2022/10/19/ems-strategies-for-ebola/
    Inform others that the person that they are caring for might be infected with a high consequence infectious disease. […] To protect yourself from exposure to infectious bodily fluids, EMS personnel should implement standard, contact, and droplet precautions, as well as airborne precautions if an aerosol generated procedure is anticipated. […] Implementation of a hierarchy of controls is a method of creating environmental changes, changes in administrative policies and work practices, and the use of personal protective equipment (PPE) to prevent exposure to infectious bodily fluids. […] If you have a patient that has confirmed EVD, the CDC recommends an impermeable gown or coverall, the use of a full face shield, a NIOSH-approved, fit tested N95 respirator or higher protection, double gloves, boot covers, and an apron.
  • #87 Infection prevention and control measures for Ebola disease in acute care settings – Canada.ca
    https://www.canada.ca/en/public-health/services/diseases/ebola/health-professionals-ebola/infection-prevention-control-measures-healthcare-settings.html
    Environmental cleaning staff should, at minimum, wear the same level of protection as HCWs providing care to the patient. […] Patients, their visitors, families and decision makers should be educated about the additional precautions being used, the duration of precautions, as well as the prevention of transmission of disease to others, with a particular focus on hand hygiene and respiratory hygiene. […] The decision to discontinue precautions for PUIs or patients with confirmed EBOD should be made on a case-by-case basis, jointly in consultation with the IPC program, infectious disease specialists, and public health officials.
  • #88
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Community engagement is key to successfully controlling any outbreak. Outbreak control relies on using a range of interventions, such as clinical care, surveillance and contact tracing, laboratory services, infection prevention and control in health facilities, safe and dignified burials, vaccination (only for Ebola virus disease) and social mobilization. […] Raising awareness of risk factors and protective measures that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors: […] Reduce the risk of human-to-human transmission arising from direct or close contact with infected people, particularly with their body fluids. Close physical contact with Ebola patients should be avoided. Patients should be isolated in a designated treatment center for early care and to avoid transmission at home.
  • #89
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Community engagement is key to successfully controlling any outbreak. Outbreak control relies on using a range of interventions, such as clinical care, surveillance and contact tracing, laboratory services, infection prevention and control in health facilities, safe and dignified burials, vaccination (only for Ebola virus disease) and social mobilization. […] Raising awareness of risk factors and protective measures that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors: […] Reduce the risk of human-to-human transmission arising from direct or close contact with infected people, particularly with their body fluids. Close physical contact with Ebola patients should be avoided. Patients should be isolated in a designated treatment center for early care and to avoid transmission at home.
  • #90 Epidemiology and Prevention of Ebola Virus Disease: Challenges and Strategies
    https://www.walshmedicalmedia.com/open-access/epidemiology-and-prevention-of-ebola-virus-disease-challenges-and-strategies-132129.html
    Ebola Virus Disease (EVD) is a severe, often fatal illness caused by the Ebola virus, which primarily affects humans and non-human primates. […] The spread of Ebola virus can be significantly reduced through a combination of public health measures and individual protective actions. The most effective methods of prevention include: […] Rapid identification of individuals with symptoms of EVD and their immediate isolation can help reduce transmission. […] In recent years, a vaccine known as rVSV-ZEBOV has been developed and shown to be highly effective in preventing EVD. […] Public education campaigns are important for raising awareness about how EVD spreads and the steps people can take to protect themselves.
  • #91
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Community engagement is key to successfully controlling any outbreak. Outbreak control relies on using a range of interventions, such as clinical care, surveillance and contact tracing, laboratory services, infection prevention and control in health facilities, safe and dignified burials, vaccination (only for Ebola virus disease) and social mobilization. […] Raising awareness of risk factors and protective measures that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors: […] Reduce the risk of human-to-human transmission arising from direct or close contact with infected people, particularly with their body fluids. Close physical contact with Ebola patients should be avoided. Patients should be isolated in a designated treatment center for early care and to avoid transmission at home.
  • #92
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Community engagement is key to successfully controlling any outbreak. Outbreak control relies on using a range of interventions, such as clinical care, surveillance and contact tracing, laboratory services, infection prevention and control in health facilities, safe and dignified burials, vaccination (only for Ebola virus disease) and social mobilization. […] Raising awareness of risk factors and protective measures that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors: […] Reduce the risk of human-to-human transmission arising from direct or close contact with infected people, particularly with their body fluids. Close physical contact with Ebola patients should be avoided. Patients should be isolated in a designated treatment center for early care and to avoid transmission at home.
  • #93 Epidemiology and Prevention of Ebola Virus Disease: Challenges and Strategies
    https://www.walshmedicalmedia.com/open-access/epidemiology-and-prevention-of-ebola-virus-disease-challenges-and-strategies-132129.html
    Ebola Virus Disease (EVD) is a severe, often fatal illness caused by the Ebola virus, which primarily affects humans and non-human primates. […] The spread of Ebola virus can be significantly reduced through a combination of public health measures and individual protective actions. The most effective methods of prevention include: […] Rapid identification of individuals with symptoms of EVD and their immediate isolation can help reduce transmission. […] In recent years, a vaccine known as rVSV-ZEBOV has been developed and shown to be highly effective in preventing EVD. […] Public education campaigns are important for raising awareness about how EVD spreads and the steps people can take to protect themselves.
  • #94 Our fight against Ebola | Malteser International
    https://www.malteser-international.org/en/current-issues/our-response/health/what-is-ebola.html
    Vaccination of medical staff […] Ring vaccinations to protect relatives and other contacts of Ebola infected persons […] Educational measures are therefore among the most important long-term preventive measures. […] By spreading knowledge about protection against the disease, its symptoms and how to deal with a possible infection, future epidemics can be avoided. […] In terms of prevention, we regularly conduct further training for medical staff and set up protective measures in cities threatened by outbreaks in order to prevent infections and to be able to detect first symptoms at an early stage.
  • #95 Ebola Virus Disease (EVD) | UNICEF Uganda
    https://www.unicef.org/uganda/ebola-virus-disease-evd
    UNICEF continues to leverage educational structures as avenues for information dissemination, community engagement, and engagement with community-based early learning centres, and primary and secondary schools to pass Ebola messages during school assemblies and parent-teacher association meetings. […] To prevent Ebola transmission in health facilities, institutions and communities, UNICEF and partners continue to support rapid assessments, procurement and distribution of essential Water, Sanitation and Hygiene (WASH) supplies, orient and mentor health workers and WASH resource persons on infection, prevention and control (IPC).
  • #96 Our fight against Ebola | Malteser International
    https://www.malteser-international.org/en/current-issues/our-response/health/what-is-ebola.html
    Vaccination of medical staff […] Ring vaccinations to protect relatives and other contacts of Ebola infected persons […] Educational measures are therefore among the most important long-term preventive measures. […] By spreading knowledge about protection against the disease, its symptoms and how to deal with a possible infection, future epidemics can be avoided. […] In terms of prevention, we regularly conduct further training for medical staff and set up protective measures in cities threatened by outbreaks in order to prevent infections and to be able to detect first symptoms at an early stage.
  • #97 Ebola Virus Disease (EVD) | UNICEF Uganda
    https://www.unicef.org/uganda/ebola-virus-disease-evd
    UNICEF continues to leverage educational structures as avenues for information dissemination, community engagement, and engagement with community-based early learning centres, and primary and secondary schools to pass Ebola messages during school assemblies and parent-teacher association meetings. […] To prevent Ebola transmission in health facilities, institutions and communities, UNICEF and partners continue to support rapid assessments, procurement and distribution of essential Water, Sanitation and Hygiene (WASH) supplies, orient and mentor health workers and WASH resource persons on infection, prevention and control (IPC).
  • #98 Ebola Outbreaks: Causes, Prevention, and Control
    https://www.everydayhealth.com/ebola/guide/outbreaks/
    Because Ebola has the potential to rapidly spread severe illness, keeping the disease contained and preventing outbreaks is vital to global health. […] The CDC moved to educate healthcare providers on how to identify patients suspected of having Ebola and isolate them. […] In Sierra Leone during the 2014 outbreak, workers went door to door to reach 1.5 million households and share information on ways families could protect themselves against Ebola virus disease, helping to slow transmission. […] Since 2019, two vaccine options have been developed for those at high risk of exposure to Ebola: Ervebo and Zabdeno. […] CDC researchers found that Ervebo has likely played an important role in limiting Ebola illnesses and deaths since its introduction. […] The organization Global Ebola Response says that countries large and small have stepped up to provide doctors, mobile clinics, and funding to help combat the virus.
  • #99
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    Outbreak containment measures include safe and dignified burial of the deceased, identifying people who may have been in contact with someone infected with Ebola disease and monitoring their health for 21 days, separating the healthy from the sick to prevent further spread and providing care to confirmed patients. Maintaining good hygiene and a clean environment are also important. […] Health-care workers should always take standard precautions when caring for patients, regardless of their presumed diagnosis. These include basic hand hygiene, respiratory hygiene, use of personal protective equipment (to block splashes or other contact with infected materials), safe injection practices and safe and dignified burial practices. […] Health-care workers caring for patients with suspected or confirmed Ebola disease should apply extra infection control measures to prevent contact with the patients blood and body fluids and contaminated surfaces or materials such as clothing and bedding.
  • #100 Ebola virus disease: from epidemiology to prophylaxis | Military Medical Research | Full Text
    https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-015-0035-4
    Contaminated objects of patients, like clothes and towels, should be also disinfected or burned without delay. […] Military forces should respond in a timely manner to EVD outbreak if it becomes an increasing threat to the international society. […] Thus, effective control of EVD outbreak is not only an emergency issue to medical community, but also a health protection mission to military force. […] All hospitals, laboratories and other health care facilities should follow the established standard procedure when treating patients as well as collecting and handling patients specimens. […] The adequate use of personal protective equipment recommended by the U.S. CDC is an obligation for health care providers to ensure that no skin is exposed to any possible source of infection.
  • #101 Ebola virus disease: from epidemiology to prophylaxis | Military Medical Research | Full Text
    https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-015-0035-4
    Contaminated objects of patients, like clothes and towels, should be also disinfected or burned without delay. […] Military forces should respond in a timely manner to EVD outbreak if it becomes an increasing threat to the international society. […] Thus, effective control of EVD outbreak is not only an emergency issue to medical community, but also a health protection mission to military force. […] All hospitals, laboratories and other health care facilities should follow the established standard procedure when treating patients as well as collecting and handling patients specimens. […] The adequate use of personal protective equipment recommended by the U.S. CDC is an obligation for health care providers to ensure that no skin is exposed to any possible source of infection.
  • #102 Ebola Virus and Marburg Virus Infections – Infections – MSD Manual Consumer Version
    https://www.msdmanuals.com/home/infections/arboviruses-arenaviruses-filoviruses/ebola-virus-and-marburg-virus-infections
    Staff members caring for people with Ebola must be completely covered in protective clothing, including head gear equipped with a respirator. Even though the infections are not thought to be spread through the air, precautions against such spread are taken. Other staff members must be available to help those wearing protective clothing remove the protective clothing. […] Diligently cleaning and disinfecting surfaces and equipment that may be contaminated is crucial, as is making sure that body fluids (such as blood, sweat, vomit, feces, and urine) are handled safely. […] For people who have traveled to or are in an area affected by an Ebola outbreak, the following is recommended: Using good hygiene, such as washing their hands with soap and water or an alcohol-based hand sanitizer and avoiding contact with other people’s blood and body fluids
  • #103 EMS Strategies for Ebola | NETEC
    https://netec.org/2022/10/19/ems-strategies-for-ebola/
    For a person under investigation (PUI) for EVD and who is unstablethey have unstable vital signs, vomiting, diarrhea or are otherwise likely to spread bodily fluidsthe same PPE applies. […] After transfer of care to the receiving facility the ambulance will need to be cleaned and disinfected. […] The U.S. Department of Transportation considers waste from Ebola virus disease patients to be Category A. […] Supportive care is the mainstay of treatment for patients with Ebola virus disease and if provided early can greatly increase chances of recovery. […] There are monoclonal antibody therapies that are effective against Ebola.
  • #104 Ebola disease: Prevention and risks – Canada.ca
    https://www.canada.ca/en/public-health/services/diseases/ebola/prevention-ebola.html
    Preventing Ebola disease […] There are things you can do to reduce your risk if you: […] Practice good hygiene […] Wash your hands frequently with soap and water. Use an alcohol-based hand sanitizer if soap and water are not available. […] Avoid direct contact with other people’s body fluids […] Avoid direct, unprotected contact with the body fluids and tissues of: […] Avoid high-risk areas and activities […] Avoid all places and activities that could result in exposure. This includes places where sick people are being cared for without appropriate infection control measures. […] If you can’t avoid high-risk areas or activities, reduce your risk by taking proper precautions, such as wearing: […] Avoid unprotected sexual activity […] Avoid sexual activity with anyone who is currently sick, including oral, vaginal or anal sex. […] Follow safe burial practices […] Avoid direct, unprotected contact with the body of a person who died of Ebola disease or an unknown illness. […] Avoid contact with wild animals […] Avoid contact with live and dead wild animals, including:
  • #105 Ebola Virus and Marburg Virus Infections – Infections – MSD Manual Consumer Version
    https://www.msdmanuals.com/home/infections/arboviruses-arenaviruses-filoviruses/ebola-virus-and-marburg-virus-infections
    Staff members caring for people with Ebola must be completely covered in protective clothing, including head gear equipped with a respirator. Even though the infections are not thought to be spread through the air, precautions against such spread are taken. Other staff members must be available to help those wearing protective clothing remove the protective clothing. […] Diligently cleaning and disinfecting surfaces and equipment that may be contaminated is crucial, as is making sure that body fluids (such as blood, sweat, vomit, feces, and urine) are handled safely. […] For people who have traveled to or are in an area affected by an Ebola outbreak, the following is recommended: Using good hygiene, such as washing their hands with soap and water or an alcohol-based hand sanitizer and avoiding contact with other people’s blood and body fluids
  • #106 Ebola disease: Prevention and risks – Canada.ca
    https://www.canada.ca/en/public-health/services/diseases/ebola/prevention-ebola.html
    Preventing Ebola disease […] There are things you can do to reduce your risk if you: […] Practice good hygiene […] Wash your hands frequently with soap and water. Use an alcohol-based hand sanitizer if soap and water are not available. […] Avoid direct contact with other people’s body fluids […] Avoid direct, unprotected contact with the body fluids and tissues of: […] Avoid high-risk areas and activities […] Avoid all places and activities that could result in exposure. This includes places where sick people are being cared for without appropriate infection control measures. […] If you can’t avoid high-risk areas or activities, reduce your risk by taking proper precautions, such as wearing: […] Avoid unprotected sexual activity […] Avoid sexual activity with anyone who is currently sick, including oral, vaginal or anal sex. […] Follow safe burial practices […] Avoid direct, unprotected contact with the body of a person who died of Ebola disease or an unknown illness. […] Avoid contact with wild animals […] Avoid contact with live and dead wild animals, including:
  • #107 Ebola Virus and Marburg Virus Infections – Infections – MSD Manual Consumer Version
    https://www.msdmanuals.com/home/infections/arboviruses-arenaviruses-filoviruses/ebola-virus-and-marburg-virus-infections
    Staff members caring for people with Ebola must be completely covered in protective clothing, including head gear equipped with a respirator. Even though the infections are not thought to be spread through the air, precautions against such spread are taken. Other staff members must be available to help those wearing protective clothing remove the protective clothing. […] Diligently cleaning and disinfecting surfaces and equipment that may be contaminated is crucial, as is making sure that body fluids (such as blood, sweat, vomit, feces, and urine) are handled safely. […] For people who have traveled to or are in an area affected by an Ebola outbreak, the following is recommended: Using good hygiene, such as washing their hands with soap and water or an alcohol-based hand sanitizer and avoiding contact with other people’s blood and body fluids
  • #108 Ebola Virus Disease (EVD) | UNICEF Uganda
    https://www.unicef.org/uganda/ebola-virus-disease-evd
    Ebola is very infectious, kills in a short time BUT can be prevented through early treatment with trained health professionals. […] Report all suspected cases to the nearest health facility immediately. […] People who are suspected to have died from Ebola must be buried immediately, by a trained Ministry of Health burial team to prevent the spread of Ebola. […] Disinfect the bedding and clothing of any person suspected to have died from Ebola with JIK. […] Wash your hands thoroughly with soap and clean water after handling a patient infected with Ebola or the body of a person who has died from Ebola. […] Avoid direct contact with body fluids of a person suspected to be suffering from Ebola by using protective materials e.g. gloves and masks. […] People handling the body of a person who is suspected to have died of Ebola should wear strong protective materials like gloves and masks.
  • #109 Ebola Virus Disease – Traveler Summary – TripPrep.com
    https://tripprep.com/library/ebola-virus-disease
    Ebola virus disease (EVD) is a rare, severe infection that occurs throughout sub-Saharan Africa and is mainly transmitted through direct skin or mucous-membrane contact with the blood or bodily fluids of infected patients or corpses or via contact with surfaces and objects contaminated with bodily fluids of infected persons. […] Prevention includes avoiding risk behaviors. […] Personal protective measures (regardless of vaccination status) remain the key prevention strategy. Avoid the risk behaviors described above. No antivirals for self-treatment are available. […] Additionally, if traveling to affected countries: Avoid direct contact with infected bodily fluids from persons with a current or recent EVD diagnosis, with surfaces or items that were contaminated by EVD patients (live or deceased), with corpses, nonhuman primates, bats (including caves and other places where bats congregate), and with health care environments that may have become contaminated.
  • #110 Ebola virus disease – UF Health
    https://ufhealth.org/conditions-and-treatments/ebola-virus-disease
    A vaccine (Ervebo) is available to prevent Ebola virus disease in people who live in the most at-risk countries during an outbreak. If you plan to travel to one of the countries where Ebola is present, the CDC recommends taking the following steps to prevent illness: […] Practice careful hygiene. Wash your hands with soap and water or an alcohol-based hand sanitizer. Avoid contact with blood and body fluids. […] Avoid contact with people who have a fever, are vomiting, or appear ill. […] Do not handle items that may have come in contact with an infected person’s blood or body fluids. This includes clothes, bedding, needles, and medical equipment. […] Avoid funeral or burial rituals that require handling the body of someone who has died from Ebola. […] Avoid contact with bats and nonhuman primates or blood, fluids, and raw meat prepared from these animals.
  • #111 What Is Ebola? Symptoms, Causes, Diagnosis, Treatment, and Prevention
    https://www.everydayhealth.com/ebola/guide/
    Measures that may prevent the spread of Ebola include the following: […] Avoid visiting areas with known outbreaks. […] Isolate infected patients from anyone who doesn’t have Ebola. […] Have healthcare workers wear protective gear, including gloves, masks, goggles, gowns, and other clothing, while caring for Ebola patients. […] Decontaminate or destroy any surfaces or materials a patient has had contact with, including syringes, needles, and other medical equipment. […] Wash hands frequently with soap and water or use an alcohol-based sanitizer. […] Avoid handling or eating bushmeat. […] Monitor anyone who comes into contact with an Ebola patient. […] The Ebola virus can survive for several hours on dry surfaces, like doorknobs and countertops. […] And it can live for up to several days at room temperature in body fluids.
  • #112 Viral Hemorrhagic Fevers | ACDC | LACDPH
    http://www.publichealth.lacounty.gov/acd/viralhemorrhagicfevers/index.htm
    VHFs can spread through contact with infected animals, infected insects or contact with the body or body fluids of an infected person depending on the type of VHF. In general VHF can spread by: […] […] Avoid traveling to areas with active outbreaks. […] […] Before travel, check the CDC Travel Health Notices site for recommendations. […] […] Travelers visiting risk areas should: […] […] Avoid physical contact with ill people and dead bodies. […] […] Avoid contact with sick or dead animals. […] […] Avoid contact with rodents, bats, primates and other animals that can carry VHFs. […] […] Avoid handling, cooking, or eating raw or undercooked bushmeat or animal products. […] […] Use insect repellents, bed nets, and protective clothing to avoid mosquito and tick bites.
  • #113 Ebola virus disease – UF Health
    https://ufhealth.org/conditions-and-treatments/ebola-virus-disease
    A vaccine (Ervebo) is available to prevent Ebola virus disease in people who live in the most at-risk countries during an outbreak. If you plan to travel to one of the countries where Ebola is present, the CDC recommends taking the following steps to prevent illness: […] Practice careful hygiene. Wash your hands with soap and water or an alcohol-based hand sanitizer. Avoid contact with blood and body fluids. […] Avoid contact with people who have a fever, are vomiting, or appear ill. […] Do not handle items that may have come in contact with an infected person’s blood or body fluids. This includes clothes, bedding, needles, and medical equipment. […] Avoid funeral or burial rituals that require handling the body of someone who has died from Ebola. […] Avoid contact with bats and nonhuman primates or blood, fluids, and raw meat prepared from these animals.
  • #114 Ebola virus disease – UF Health
    https://ufhealth.org/conditions-and-treatments/ebola-virus-disease
    A vaccine (Ervebo) is available to prevent Ebola virus disease in people who live in the most at-risk countries during an outbreak. If you plan to travel to one of the countries where Ebola is present, the CDC recommends taking the following steps to prevent illness: […] Practice careful hygiene. Wash your hands with soap and water or an alcohol-based hand sanitizer. Avoid contact with blood and body fluids. […] Avoid contact with people who have a fever, are vomiting, or appear ill. […] Do not handle items that may have come in contact with an infected person’s blood or body fluids. This includes clothes, bedding, needles, and medical equipment. […] Avoid funeral or burial rituals that require handling the body of someone who has died from Ebola. […] Avoid contact with bats and nonhuman primates or blood, fluids, and raw meat prepared from these animals.
  • #115 Ebola virus disease – UF Health
    https://ufhealth.org/conditions-and-treatments/ebola-virus-disease
    A vaccine (Ervebo) is available to prevent Ebola virus disease in people who live in the most at-risk countries during an outbreak. If you plan to travel to one of the countries where Ebola is present, the CDC recommends taking the following steps to prevent illness: […] Practice careful hygiene. Wash your hands with soap and water or an alcohol-based hand sanitizer. Avoid contact with blood and body fluids. […] Avoid contact with people who have a fever, are vomiting, or appear ill. […] Do not handle items that may have come in contact with an infected person’s blood or body fluids. This includes clothes, bedding, needles, and medical equipment. […] Avoid funeral or burial rituals that require handling the body of someone who has died from Ebola. […] Avoid contact with bats and nonhuman primates or blood, fluids, and raw meat prepared from these animals.
  • #116 Ebola virus disease – UF Health
    https://ufhealth.org/conditions-and-treatments/ebola-virus-disease
    A vaccine (Ervebo) is available to prevent Ebola virus disease in people who live in the most at-risk countries during an outbreak. If you plan to travel to one of the countries where Ebola is present, the CDC recommends taking the following steps to prevent illness: […] Practice careful hygiene. Wash your hands with soap and water or an alcohol-based hand sanitizer. Avoid contact with blood and body fluids. […] Avoid contact with people who have a fever, are vomiting, or appear ill. […] Do not handle items that may have come in contact with an infected person’s blood or body fluids. This includes clothes, bedding, needles, and medical equipment. […] Avoid funeral or burial rituals that require handling the body of someone who has died from Ebola. […] Avoid contact with bats and nonhuman primates or blood, fluids, and raw meat prepared from these animals.
  • #117 What Is Ebola? Symptoms, Causes, Diagnosis, Treatment, and Prevention
    https://www.everydayhealth.com/ebola/guide/
    Measures that may prevent the spread of Ebola include the following: […] Avoid visiting areas with known outbreaks. […] Isolate infected patients from anyone who doesn’t have Ebola. […] Have healthcare workers wear protective gear, including gloves, masks, goggles, gowns, and other clothing, while caring for Ebola patients. […] Decontaminate or destroy any surfaces or materials a patient has had contact with, including syringes, needles, and other medical equipment. […] Wash hands frequently with soap and water or use an alcohol-based sanitizer. […] Avoid handling or eating bushmeat. […] Monitor anyone who comes into contact with an Ebola patient. […] The Ebola virus can survive for several hours on dry surfaces, like doorknobs and countertops. […] And it can live for up to several days at room temperature in body fluids.
  • #118 Ebola virus disease – UF Health
    https://ufhealth.org/conditions-and-treatments/ebola-virus-disease
    A vaccine (Ervebo) is available to prevent Ebola virus disease in people who live in the most at-risk countries during an outbreak. If you plan to travel to one of the countries where Ebola is present, the CDC recommends taking the following steps to prevent illness: […] Practice careful hygiene. Wash your hands with soap and water or an alcohol-based hand sanitizer. Avoid contact with blood and body fluids. […] Avoid contact with people who have a fever, are vomiting, or appear ill. […] Do not handle items that may have come in contact with an infected person’s blood or body fluids. This includes clothes, bedding, needles, and medical equipment. […] Avoid funeral or burial rituals that require handling the body of someone who has died from Ebola. […] Avoid contact with bats and nonhuman primates or blood, fluids, and raw meat prepared from these animals.
  • #119 Ebola virus disease – UF Health
    https://ufhealth.org/conditions-and-treatments/ebola-virus-disease
    Avoid hospitals in West Africa where Ebola patients are being treated. If you need medical care, the United States embassy or consulate is often able to provide advice about facilities. […] After you return, pay attention to your health for 21 days. Seek medical care right away if you develop symptoms of Ebola, such as a fever. Tell your provider that you have been to a country where Ebola is present. […] Health care workers who may be exposed to people with Ebola should follow these steps: […] Wear PPE, including protective clothing, including masks, gloves, gowns, and eye protection. […] Practice proper infection control and sterilization measures. […] Isolate patients with Ebola from other patients. […] Avoid direct contact with the bodies of people who have died from Ebola. […] Notify health officials if you have had direct contact with the blood or body fluids of a person who is sick with Ebola.
  • #120 Ebola Virus Disease
    https://oklahoma.gov/health/health-education/acute-disease-service/disease-information/ebola-virus-disease.html
    Avoid contact with animals or with raw meat. […] Avoid hospitals where Ebola patients are being treated. The U.S. Embassy or consulate is often able to provide advice on facilities that are suitable for your needs. […] People who have traveled to a country where Ebola is being spread should seek medical care immediately if they develop fever, headache, achiness, diarrhea, vomiting, stomach pain, rash or red eyes within 21 days of traveling. Call your provider ahead of time to let them know of your symptoms and travel history to a place where Ebola is being spread.
  • #121 Ebola virus disease: from epidemiology to prophylaxis | Military Medical Research | Full Text
    https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-015-0035-4
    Since there are no specific medications broadly available to cure EVD, the most important thing is to prevent susceptible people from the infection and restrict spreading. This requires the government, public health facilities, medical units, and individuals to make concerted efforts. Military forces are indispensable when local public health systems are overwhelmed or in the case where the EVD epidemic goes out of control. […] Sufficient political support from the government is crucial for the prevention and control of the Ebola epidemic. First, a strong public health infrastructure and medical reserve should be established and improved. Most severe EVD epidemics occurred in areas where the health systems were overwhelmed or failed to identify and isolate the infection cases in a timely fashion.
  • #122 Ebola Virus Disease – PAHO/WHO | Pan American Health Organization
    https://www.paho.org/en/topics/ebola-virus-disease
    PAHO is working with countries in the region to strengthen their preparedness to detect and quickly respond to a possible imported case of Ebola. […] The Director of PAHO created a task force and an operational working group that advises and supports the implementation of the International Emergency Committee of the International Health Regulations (IHR) recommendations and coordinates the response to the possible introduction of Ebola virus disease in the Americas.
  • #123 Ebola Virus Disease – PAHO/WHO | Pan American Health Organization
    https://www.paho.org/en/topics/ebola-virus-disease
    PAHO is working with countries in the region to strengthen their preparedness to detect and quickly respond to a possible imported case of Ebola. […] The Director of PAHO created a task force and an operational working group that advises and supports the implementation of the International Emergency Committee of the International Health Regulations (IHR) recommendations and coordinates the response to the possible introduction of Ebola virus disease in the Americas.
  • #124 Ebola preparedness and response | UNICEF Eastern and Southern Africa
    https://www.unicef.org/esa/ebola-preparedness-and-response
    The quick and effective response in Uganda has demonstrated the value of investing in preparedness. The three confirmed cases were rapidly detected and isolated. […] In Uganda, vaccinations, expanding preparedness to all priority districts, and ramping-up community engagement, all remain paramount for mitigating the risk. And yet all are under-resourced. […] UNICEF works with partners on three broad areas to respond support the overarching goal of ultimately defeating Ebola and getting to zero cases. Risk communication and community engagement to inform, protect and engage communities. […] Infection prevention and control to help prevent further spread of the disease. We have installed handwashing units in health facilities, schools and critical transit sites. We distribute supplies, including thermometers and chlorine to treat water. And we’ve enabled people to gain access to safe water.
  • #125 Ebola Virus Disease – PAHO/WHO | Pan American Health Organization
    https://www.paho.org/en/topics/ebola-virus-disease
    PAHO is working with countries in the region to strengthen their preparedness to detect and quickly respond to a possible imported case of Ebola. […] The Director of PAHO created a task force and an operational working group that advises and supports the implementation of the International Emergency Committee of the International Health Regulations (IHR) recommendations and coordinates the response to the possible introduction of Ebola virus disease in the Americas.
  • #126 Ebola Virus Disease – PAHO/WHO | Pan American Health Organization
    https://www.paho.org/en/topics/ebola-virus-disease
    PAHO is working with countries in the region to strengthen their preparedness to detect and quickly respond to a possible imported case of Ebola. […] The Director of PAHO created a task force and an operational working group that advises and supports the implementation of the International Emergency Committee of the International Health Regulations (IHR) recommendations and coordinates the response to the possible introduction of Ebola virus disease in the Americas.
  • #127 Ebola preparedness and response | UNICEF Eastern and Southern Africa
    https://www.unicef.org/esa/ebola-preparedness-and-response
    The quick and effective response in Uganda has demonstrated the value of investing in preparedness. The three confirmed cases were rapidly detected and isolated. […] In Uganda, vaccinations, expanding preparedness to all priority districts, and ramping-up community engagement, all remain paramount for mitigating the risk. And yet all are under-resourced. […] UNICEF works with partners on three broad areas to respond support the overarching goal of ultimately defeating Ebola and getting to zero cases. Risk communication and community engagement to inform, protect and engage communities. […] Infection prevention and control to help prevent further spread of the disease. We have installed handwashing units in health facilities, schools and critical transit sites. We distribute supplies, including thermometers and chlorine to treat water. And we’ve enabled people to gain access to safe water.
  • #128 Ebola Outbreaks: Causes, Prevention, and Control
    https://www.everydayhealth.com/ebola/guide/outbreaks/
    Because Ebola has the potential to rapidly spread severe illness, keeping the disease contained and preventing outbreaks is vital to global health. […] The CDC moved to educate healthcare providers on how to identify patients suspected of having Ebola and isolate them. […] In Sierra Leone during the 2014 outbreak, workers went door to door to reach 1.5 million households and share information on ways families could protect themselves against Ebola virus disease, helping to slow transmission. […] Since 2019, two vaccine options have been developed for those at high risk of exposure to Ebola: Ervebo and Zabdeno. […] CDC researchers found that Ervebo has likely played an important role in limiting Ebola illnesses and deaths since its introduction. […] The organization Global Ebola Response says that countries large and small have stepped up to provide doctors, mobile clinics, and funding to help combat the virus.
  • #129 Ebola virus disease: from epidemiology to prophylaxis | Military Medical Research | Full Text
    https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-015-0035-4
    Since there are no specific medications broadly available to cure EVD, the most important thing is to prevent susceptible people from the infection and restrict spreading. This requires the government, public health facilities, medical units, and individuals to make concerted efforts. Military forces are indispensable when local public health systems are overwhelmed or in the case where the EVD epidemic goes out of control. […] Sufficient political support from the government is crucial for the prevention and control of the Ebola epidemic. First, a strong public health infrastructure and medical reserve should be established and improved. Most severe EVD epidemics occurred in areas where the health systems were overwhelmed or failed to identify and isolate the infection cases in a timely fashion.
  • #130 Ebola virus disease: from epidemiology to prophylaxis | Military Medical Research | Full Text
    https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-015-0035-4
    Contaminated objects of patients, like clothes and towels, should be also disinfected or burned without delay. […] Military forces should respond in a timely manner to EVD outbreak if it becomes an increasing threat to the international society. […] Thus, effective control of EVD outbreak is not only an emergency issue to medical community, but also a health protection mission to military force. […] All hospitals, laboratories and other health care facilities should follow the established standard procedure when treating patients as well as collecting and handling patients specimens. […] The adequate use of personal protective equipment recommended by the U.S. CDC is an obligation for health care providers to ensure that no skin is exposed to any possible source of infection.
  • #131 Ebola virus disease: from epidemiology to prophylaxis | Military Medical Research | Full Text
    https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-015-0035-4
    Contaminated objects of patients, like clothes and towels, should be also disinfected or burned without delay. […] Military forces should respond in a timely manner to EVD outbreak if it becomes an increasing threat to the international society. […] Thus, effective control of EVD outbreak is not only an emergency issue to medical community, but also a health protection mission to military force. […] All hospitals, laboratories and other health care facilities should follow the established standard procedure when treating patients as well as collecting and handling patients specimens. […] The adequate use of personal protective equipment recommended by the U.S. CDC is an obligation for health care providers to ensure that no skin is exposed to any possible source of infection.
  • #132 Ebola virus disease: from epidemiology to prophylaxis | Military Medical Research | Full Text
    https://mmrjournal.biomedcentral.com/articles/10.1186/s40779-015-0035-4
    Contaminated objects of patients, like clothes and towels, should be also disinfected or burned without delay. […] Military forces should respond in a timely manner to EVD outbreak if it becomes an increasing threat to the international society. […] Thus, effective control of EVD outbreak is not only an emergency issue to medical community, but also a health protection mission to military force. […] All hospitals, laboratories and other health care facilities should follow the established standard procedure when treating patients as well as collecting and handling patients specimens. […] The adequate use of personal protective equipment recommended by the U.S. CDC is an obligation for health care providers to ensure that no skin is exposed to any possible source of infection.
  • #133 Azthena logo with the word Azthena
    https://www.news-medical.net/health/Ebola-Virus-Prevention.aspx
    When traveling or staying in an area affected by Ebola outbreak, it is important to adhere to three key preventive interventions in order to minimize the risk of infection. A single lapse in proper infection control can set in motion another chain of transmission and worsen the outbreak. […] First, meticulous infection control should be implemented wherever possible. The greatest risk of viral transmission does not arise from diagnosed patients, but from the delayed detection and isolation of the infected individuals. […] Second, meat from hunted wild animals should be avoided (so-called bush meat). In places where consumption of such meat continues, it is necessary to encourage safer slaughter and handling procedures. […] Third, there is a dire need for modification of the traditional funeral practices, which often represent sources of infection due to the contact with bodily fluids of the deceased individuals. As this is a culturally sensitive matter, appropriate outreach, education and support are crucial.
  • #134 Azthena logo with the word Azthena
    https://www.news-medical.net/health/Ebola-Virus-Prevention.aspx
    When traveling or staying in an area affected by Ebola outbreak, it is important to adhere to three key preventive interventions in order to minimize the risk of infection. A single lapse in proper infection control can set in motion another chain of transmission and worsen the outbreak. […] First, meticulous infection control should be implemented wherever possible. The greatest risk of viral transmission does not arise from diagnosed patients, but from the delayed detection and isolation of the infected individuals. […] Second, meat from hunted wild animals should be avoided (so-called bush meat). In places where consumption of such meat continues, it is necessary to encourage safer slaughter and handling procedures. […] Third, there is a dire need for modification of the traditional funeral practices, which often represent sources of infection due to the contact with bodily fluids of the deceased individuals. As this is a culturally sensitive matter, appropriate outreach, education and support are crucial.
  • #135 Azthena logo with the word Azthena
    https://www.news-medical.net/health/Ebola-Virus-Prevention.aspx
    When traveling or staying in an area affected by Ebola outbreak, it is important to adhere to three key preventive interventions in order to minimize the risk of infection. A single lapse in proper infection control can set in motion another chain of transmission and worsen the outbreak. […] First, meticulous infection control should be implemented wherever possible. The greatest risk of viral transmission does not arise from diagnosed patients, but from the delayed detection and isolation of the infected individuals. […] Second, meat from hunted wild animals should be avoided (so-called bush meat). In places where consumption of such meat continues, it is necessary to encourage safer slaughter and handling procedures. […] Third, there is a dire need for modification of the traditional funeral practices, which often represent sources of infection due to the contact with bodily fluids of the deceased individuals. As this is a culturally sensitive matter, appropriate outreach, education and support are crucial.
  • #136 Ebola virus disease in children: epidemiology, pathogenesis, management, and prevention | Pediatric Research
    https://www.nature.com/articles/s41390-023-02873-y
    Interruption of community and nosocomial transmission is achieved through educational and sociological measures, isolation of suspected or confirmed cases for care, strict infection control protocols, contact tracing, and vaccination. […] Safe and dignified burials help to prevent transmission while also emphasizing inclusion of family members and encouraging religious rites. […] The structure of ETUs necessarily restricts the presence of uninfected caregivers, which can create a setting that is not safe or comforting to children. Adaptations to this structure, including recruiting survivors to help with the care of children, can help to address these difficulties. […] Vaccines to protect against EVD have emerged rapidly since 2013. Currently, two regimens are being used to provide protection against EBOV: the Merck rVSV-ZEBOV regimen (sold as Ervebo) and the Janssen Ad26.ZEBOV/MVA-BN-Filo regimen (sold as Zabdeno/Mvabea).
  • #137 Ebola virus disease in children: epidemiology, pathogenesis, management, and prevention | Pediatric Research
    https://www.nature.com/articles/s41390-023-02873-y
    Interruption of community and nosocomial transmission is achieved through educational and sociological measures, isolation of suspected or confirmed cases for care, strict infection control protocols, contact tracing, and vaccination. […] Safe and dignified burials help to prevent transmission while also emphasizing inclusion of family members and encouraging religious rites. […] The structure of ETUs necessarily restricts the presence of uninfected caregivers, which can create a setting that is not safe or comforting to children. Adaptations to this structure, including recruiting survivors to help with the care of children, can help to address these difficulties. […] Vaccines to protect against EVD have emerged rapidly since 2013. Currently, two regimens are being used to provide protection against EBOV: the Merck rVSV-ZEBOV regimen (sold as Ervebo) and the Janssen Ad26.ZEBOV/MVA-BN-Filo regimen (sold as Zabdeno/Mvabea).
  • #138 Azthena logo with the word Azthena
    https://www.news-medical.net/health/Ebola-Virus-Prevention.aspx
    When traveling or staying in an area affected by Ebola outbreak, it is important to adhere to three key preventive interventions in order to minimize the risk of infection. A single lapse in proper infection control can set in motion another chain of transmission and worsen the outbreak. […] First, meticulous infection control should be implemented wherever possible. The greatest risk of viral transmission does not arise from diagnosed patients, but from the delayed detection and isolation of the infected individuals. […] Second, meat from hunted wild animals should be avoided (so-called bush meat). In places where consumption of such meat continues, it is necessary to encourage safer slaughter and handling procedures. […] Third, there is a dire need for modification of the traditional funeral practices, which often represent sources of infection due to the contact with bodily fluids of the deceased individuals. As this is a culturally sensitive matter, appropriate outreach, education and support are crucial.
  • #139 Factsheet about Ebola disease
    https://www.ecdc.europa.eu/en/infectious-disease-topics/ebola-virus-disease/facts/factsheet-about-ebola-disease
    In previous outbreaks, isolation of infected patients and the implementation of appropriate IPC measures has been shown to effectively stop the spread of disease. […] It is advisable to avoid habitats that may be populated by bats, such as caves or mines in areas/countries where ebolaviruses might be present. The handling or consumption of any type of bushmeat should be avoided, as should close contact with wild animals (such as monkeys, forest antelopes, rodents and bats – alive or dead). […] The appropriate use of infection control precautions and the application of strict barrier nursing procedures are critical to preventing nosocomial transmission. Implementation of appropriate infection control measures in healthcare settings, including use of personal protective equipment, will minimise the risk of transmission of ebolaviruses.
  • #140 Ebola virus disease in children: epidemiology, pathogenesis, management, and prevention | Pediatric Research
    https://www.nature.com/articles/s41390-023-02873-y
    Interruption of community and nosocomial transmission is achieved through educational and sociological measures, isolation of suspected or confirmed cases for care, strict infection control protocols, contact tracing, and vaccination. […] Safe and dignified burials help to prevent transmission while also emphasizing inclusion of family members and encouraging religious rites. […] The structure of ETUs necessarily restricts the presence of uninfected caregivers, which can create a setting that is not safe or comforting to children. Adaptations to this structure, including recruiting survivors to help with the care of children, can help to address these difficulties. […] Vaccines to protect against EVD have emerged rapidly since 2013. Currently, two regimens are being used to provide protection against EBOV: the Merck rVSV-ZEBOV regimen (sold as Ervebo) and the Janssen Ad26.ZEBOV/MVA-BN-Filo regimen (sold as Zabdeno/Mvabea).
  • #141 Ebola virus disease in children: epidemiology, pathogenesis, management, and prevention | Pediatric Research
    https://www.nature.com/articles/s41390-023-02873-y
    Interruption of community and nosocomial transmission is achieved through educational and sociological measures, isolation of suspected or confirmed cases for care, strict infection control protocols, contact tracing, and vaccination. […] Safe and dignified burials help to prevent transmission while also emphasizing inclusion of family members and encouraging religious rites. […] The structure of ETUs necessarily restricts the presence of uninfected caregivers, which can create a setting that is not safe or comforting to children. Adaptations to this structure, including recruiting survivors to help with the care of children, can help to address these difficulties. […] Vaccines to protect against EVD have emerged rapidly since 2013. Currently, two regimens are being used to provide protection against EBOV: the Merck rVSV-ZEBOV regimen (sold as Ervebo) and the Janssen Ad26.ZEBOV/MVA-BN-Filo regimen (sold as Zabdeno/Mvabea).
  • #142
    https://www.who.int/news-room/fact-sheets/detail/ebola-virus-disease
    To mitigate the risk of this transmission, a semen testing programme should be implemented to: […] offer counselling to male survivors and their sexual partners to inform them of the potential risk and support them adhering to safer sex practices (including condom provision and good hand and personal hygiene); […] offer monthly semen testing until they have had two consecutive negative test results; and […] after two consecutive negative tests, survivors can safely resume normal sexual practices with minimized risk of virus transmission. […] In the absence of a semen testing programme, male survivors should follow safer sex practices for 12 months. […] Survivor care programmes should encompass care for pregnant and breastfeeding women after their recovery.
  • #143 Ebola Virus Disease (EVD) | UNICEF Uganda
    https://www.unicef.org/uganda/ebola-virus-disease-evd
    UNICEF continues to leverage educational structures as avenues for information dissemination, community engagement, and engagement with community-based early learning centres, and primary and secondary schools to pass Ebola messages during school assemblies and parent-teacher association meetings. […] To prevent Ebola transmission in health facilities, institutions and communities, UNICEF and partners continue to support rapid assessments, procurement and distribution of essential Water, Sanitation and Hygiene (WASH) supplies, orient and mentor health workers and WASH resource persons on infection, prevention and control (IPC).