Materiały źródłowe

• #1 Parotid Benign Tumors in Beverly Hills, CA | Center for Advanced Parotid Surgery

  https://www.parotidsurgerymd.com/conditions/parotid-tumors/

  Most of the tumors of the salivary glands happen in the parotid gland; close to 80% of salivary gland tumors occur in the parotid gland. Fortunately majority of those tumors, or roughly 80%, are benign or non-cancerous in the parotid gland. In other words, only 20% of tumors in the parotid gland are cancerous. […] There are 15 different types of benign tumors that occur in the salivary glands. Pleomorphic adenomas & Warthin’s tumor are the most common together making up 88% of benign tumors. The remaining tumors are very uncommon and are usually slow growing & painless. […] This type of tumor accounts for the vast majority of all parotid tumors. They occur not only in the parotid gland but have been found in all salivary glands including submandibular gland, sublingual and even in the minor salivary glands lining the mouth, nose & throat. They tend to grow slowly and have a genetic makeup that predisposes them to transform into a cancer if left in the body for too long. It also has little legs on its surface and so requires meticulousness and patience by your surgeon to remove without leaving any of it behind; if removed incompletely then the tumor will grow in time (7-10 years) to show itself again. Pleomorphic adenomas can grow to become very large or massive. Due to the potential to grow large & transform into an aggressive cancer, it is recommended that pleomorphic adenomas be removed.

• #1 Parotid tumors | UM Health-Sparrow

  https://www.uofmhealthsparrow.org/departments-conditions/conditions/parotid-tumors

  Parotid tumors often cause swelling in the face or jaw. Other symptoms include problems swallowing or a loss of facial movement. […] Diagnosis and treatment for parotid tumors is often done by doctors who specialize in problems that affect the ear, nose and throat. These doctors are called ENT specialists or otolaryngologists. […] Parotid tumor treatment often involves surgery to remove the tumor. If the tumor is cancerous, you might need more treatment. This could be with radiation therapy and chemotherapy. […] Parotid tumor surgery can be complex. It requires well-trained surgeons and specialists for the best outcome. If you’re facing surgery for a parotid tumor, meet with your surgeon before your operation to ask questions. Learning more about the procedure can help you feel more comfortable about your treatment plan.

• #1 Parotid tumors – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/parotid-tumor/diagnosis-treatment/drc-20579012

  Parotid tumor treatment often involves surgery to remove the tumor. If the tumor is cancerous, you might need more treatment. This could be with radiation therapy and chemotherapy. […] Operations used to remove parotid tumors include: […] Removing part of the parotid gland. For most parotid tumors, surgeons may cut away the tumor and some of the healthy parotid gland tissue around it. The part of the parotid gland that’s left continues working as before. […] Removing all of the parotid gland. Surgery to remove all of the parotid gland is called parotidectomy. It might be needed for larger tumors, tumors that are cancerous and those that affect the deeper parts of the parotid gland. […] Removing more tissue to get all of the cancer. If parotid gland cancer has grown into nearby bone and muscles, some of these may be taken out with the parotid gland. Surgeons try to remove all of the cancer and a small amount of the healthy tissue that surrounds it. Then they work to repair the area so that you can continue to chew, swallow, speak, breathe and move your face. This may involve moving skin, tissue, bone or nerves from other parts of your body to make repairs. This type of surgery isn’t needed for parotid tumors that aren’t cancerous.

• #1 Salivary Gland Neoplasms Treatment & Management: Medical Therapy, Surgical Therapy, Intraoperative Details

  https://emedicine.medscape.com/article/852373-treatment

  Carefully planned and executed surgical excision is the primary treatment for all primary salivary gland tumors. The principles of surgery vary with the site of origin and are discussed as such. […] Superficial parotidectomy with identification and dissection of the facial nerve is the minimum operation for diagnosis and treatment of parotid masses. Neither incisional biopsy nor enucleation should be performed for parotid masses. […] Surgery is the primary treatment of malignant tumors of the salivary glands. This is often combined with postoperative radiation therapy, depending on the specific tumor characteristics and stage. The extent of surgery is based on the size of the tumor, local extension, and neck metastases. The facial nerve is spared unless it is directly involved. Postoperative adjuvant radiation therapy is recommended for high-grade malignancies and high-stage cancers.

• #1 Parotid tumors – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/parotid-tumor/diagnosis-treatment/drc-20579012

  Sometimes a sample of tumor tissue is tested during surgery to see if it’s cancer. A doctor who uses blood and body tissue to diagnose diseases, who is called a pathologist, looks at the sample right away. The pathologist tells the surgeon if the tumor is cancerous. This helps the surgeon decide how much of the parotid gland to remove. […] The parotid gland surrounds the nerve that moves the muscles of the face. This nerve is called the facial nerve. Surgeons take special care to avoid hurting it. […] Parotid tumor surgery can be complex. It requires well-trained surgeons and specialists for the best outcome. If you’re facing surgery for a parotid tumor, meet with your surgeon before your operation to ask questions. Learning more about the procedure can help you feel more comfortable about your treatment plan.

• #1 Parotidectomy (Parotid Gland Tumor Surgery) | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/salivary-gland/salivary-gland-cancer-treatment/parotidectomy-parotid-gland-tumor-surgery

  MSKs parotid gland surgeons, including Ian Ganly, have extensive experience in using precise techniques that help preserve the facial nerve. […] For many people with parotid gland tumors, surgery performed by a head and neck surgeon is the main treatment. This operation is called a parotidectomy. […] Treating parotid gland tumors requires great precision on the part of your surgical team because the facial nerve is nearby. The facial nerve controls your ability to close your eyes, raise your eyebrows, and smile. […] Preserving the facial nerve is an important priority when removing a parotid gland tumor. The facial nerve is typically identified and protected during a parotidectomy. However, there is a chance that the nerve may be adversely affected by the tumor itself or by the surgical procedure needed to remove the tumor.

• #1 Salivary Gland Neoplasms Treatment & Management: Medical Therapy, Surgical Therapy, Intraoperative Details

  https://emedicine.medscape.com/article/852373-treatment

  The facial nerve should not be sacrificed for benign tumors. […] On the basis of the histologic classification and clinical stage, a useful management schema has been developed and is shown in the Further Reading section. […] Group 1 includes T1 and T2 low-grade tumors (eg, low-grade mucoepidermoid carcinoma, acinic cell carcinoma). For these tumors, perform parotidectomy (superficial or total) with an adequate margin of normal tissue with preservation of the facial nerve. […] Group 2 includes T1 and T2 tumors with high-grade features (eg, high-grade mucoepidermoid carcinoma, adenoid cystic carcinoma, squamous cell carcinoma, adenocarcinoma, carcinoma ex-pleomorphic adenoma). For these tumors, perform total parotidectomy, including the first-echelon lymph nodes. […] Group 3 tumors commonly require sacrifice of the lingual and hypoglossal nerves to obtain clear margins. Perform selective or modified radical neck dissection and administer postoperative radiation therapy.

• #1 Parotid tumors – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/parotid-tumor/diagnosis-treatment/drc-20579012

  Radiation therapy uses powerful energy beams to kill cancer cells. The energy can come from sources such as X-rays and protons. […] Radiation therapy is used to treat parotid gland cancers. Radiation therapy might be recommended after surgery. The radiation can kill any cancer cells that remain. If surgery isn’t possible, radiation therapy might be the first treatment for parotid cancers. […] Chemotherapy uses strong medicines to kill cancer cells. Chemotherapy is sometimes used to treat parotid gland cancers. It might be needed if there’s a risk that the cancer might spread or if surgery isn’t an option. In these situations, chemotherapy might be done at the same time as radiation therapy. […] Targeted therapy uses medicines that attack specific chemicals in the cancer cells. By blocking these chemicals, targeted treatments can cause cancer cells to die. […] Targeted therapy might be an option for treating parotid gland cancers when other treatments haven’t helped.

• #1 Malignant Parotid Tumors: Practice Essentials, Anatomy, Diagnosis

  https://emedicine.medscape.com/article/1289616-overview

  The parotid glands are the largest salivary glands in humans and are frequently involved in disease processes. Approximately 25% of parotid masses are nonneoplastic; the remaining 75% are neoplastic. […] Generally, therapy for parotid malignancy is complete surgical resection followed, when indicated, by radiation therapy. […] Following resection of the tumor specimen, most wounds can be closed primarily. However, the presence of extension of the tumor to the overlying skin or surrounding structures may require reconstructive procedures. […] Postoperative radiation is usually indicated for all parotid malignancies with the exception of small low-grade tumors with no evidence of local invasion or nodal/distant spread. […] Because of the many histologic subtypes of parotid malignancies, a general statement regarding the usefulness of adjunctive therapy cannot be made.

• #1 Parotidectomy: Procedure Details, Recovery & Outlook

  https://my.clevelandclinic.org/health/treatments/24057-parotidectomy-parotid-gland-tumor-surgery

  Removing your parotid gland while preserving your facial nerves functioning requires expertise and care during surgery. […] A parotidectomy can treat cancerous tumors and prevent cancer from spreading. It can also prevent benign tumors from becoming malignant or growing so large that they damage your facial nerve or other tissue. […] Parotidectomy is major surgery, but its also a standard, reliable treatment for eliminating tumors that can damage essential nerves and tissue in your head and neck. […] Your healthcare provider will supply you with the necessary resources to prepare for a parotidectomy. Still, the best way to prepare is to ensure you get answers to all of your questions beforehand. […] Youll receive instructions on caring for your wound and drain before being released from the hospital.

• #1 Nursing Teaching for Parotidectomy | Iowa Head and Neck Protocols

  https://medicine.uiowa.edu/iowaprotocols/nursing-teaching-parotidectomy

  Nursing Teaching for Parotidectomy […] Patient/family will verbalize understanding of postoperative diet. […] Nausea/vomiting may be present the first 24 hours after surgery as a side effect of general anesthetic agents. […] Antiemetics will be ordered on a PRN basis IV/PO/PR. […] Postoperative diet will begin with clear liquids and advance as patient tolerates when nausea/vomiting resolves. […] Patient may prefer soft diet due to discomfort with chewing after surgery. […] Patient/family will verbalize understanding of postoperative positioning and activity. […] HOB is elevated 30. […] Patient will be encouraged to ambulate and sit in chair when fully awake and alert (UAL). […] Patient/family will verbalize understanding of pain assessment and medication administration. […] Introduce and explain use of pain assessment scales (Simple Descriptive, 0-10 Numeric). Identify patient’s preference.

• #1 Nursing Teaching for Parotidectomy | Iowa Head and Neck Protocols

  https://medicine.uiowa.edu/iowaprotocols/nursing-teaching-parotidectomy

  Patient/family will verbalize understanding of assessments and interventions related to postoperative neck dissection care. […] Skin flap will be monitored for adequate circulation. […] Avoid constrictive clothing around neck. […] Neck may have sunken or depressed appearance on side of dissection. […] Patient may experience loss of sensation to posterior scalp, neck, and shoulder. […] Patient may experience weakness, discomfort and limited mobility to shoulder. Patient will be assessed during postoperative clinic visits and may be instructed on exercises or referred to physical therapy. […] Postoperative pain manifested primarily by headache. […] Patient/family will verbalize understanding of potential alterations in physical appearance/body image/sensory changes. […] A depression behind the mandible may result from the surgical resection.

• #1 Parotid Gland Tumors: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/parotid-tumor

  A parotid gland tumor is a rare tumor on one of your salivary glands. Most parotid tumors are benign (noncancerous), but they can be cancerous. Both types cause a lump in front of one of your ears. Surgery treats both types and cures noncancerous parotid gland tumors. Providers may also use radiation therapy to treat cancerous tumors. […] Treatment typically involves surgery to remove the tumor. Surgery cures noncancerous tumors and may cure cancerous ones, as well. But cancerous parotid gland tumors can come back (recur). […] Parotidectomy, which is surgery to remove part or all of your parotid gland, is the most common treatment for cancerous and noncancerous tumors. People with cancerous tumors also receive radiation therapy after surgery. […] Cancerous parotid gland tumors can come back. Here are some suggestions for taking care of yourself after treatment: Attend your follow-up appointments: Tests to look for recurring parotid gland cancer may detect cancerous tumors before they spread. […] Youll have frequent follow-up appointments if you had treatment for a cancerous parotid gland tumor. But you should contact your healthcare provider if you notice changes like a new lump developing in front of one of your ears.

• #1 Parotidectomy (Parotid Gland Tumor Surgery) | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/salivary-gland/salivary-gland-cancer-treatment/parotidectomy-parotid-gland-tumor-surgery

  Our experts have developed highly specialized techniques for treating facial paralysis so people can regain these abilities after treatment. […] This procedure is known as facial reanimation. It may be done when the tumor is being removed or even years after treatment in some cases. […] We also offer an innovative method for facial reanimation called the dual-babysitter technique. It involves rewiring nerves from both the tongue and biting muscle to the facial muscles, in combination with nerve grafts.

• #1 Salivary Gland Cancer | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/salivary-gland-cancer.html

  Salivary gland tumors form when a cell in a salivary gland mutates and starts rapidly growing and dividing. Most salivary gland tumors are benign, meaning they are not cancer and do not spread to other parts of the body. […] Some are malignant, or cancer. These tumors can spread beyond their original location to nearby tissue, lymph nodes and distant parts of the body. […] Every patient with salivary gland cancer is different. Treatment plans can change drastically based on the cancers subtype, as well as the tumors exact location. Just a few millimeters can make a huge difference. The right treatment plan can greatly reduce the chance that the cancer returns and help maintain your quality of life, including your ability to speak, swallow and hear. […] At MD Anderson you’ll get care from a team of salivary gland cancer experts.

• #1 Salivary Gland Cancer | Cancer of the Salivary Glands | University of Michigan Rogel Cancer Center]

  https://www.rogelcancercenter.org/head-and-neck-cancer/salivary-gland

  Patient Care and Treatment The Head and Neck Oncology Program follows a team approach to care. Our patients with salivary glands have their situation discussed not only by our head and neck oncologists, but also by team surgeons and pathologists. By having everyone involved, a personalized treatment plan is developed. In most cases, this discussion happens the same day as the appointment. […] Support Undergoing treatment for cancer — particularly head and neck cancer — is a difficult and sometimes painful process. To help, we’ve put together a page filled with Resources and Support for Patients. There are links to articles about treatment, survivor stories and information about support groups. Since our program is part of the U-M Rogel Cancer Center, our patients have access to a range of Patient Support Services. To fully understand what this means, please take time to visit the support services area of this website. We outline the services available to all of our patients at every point in their care.

• #1 Salivary gland tumors | UK Healthcare

  https://ukhealthcare.uky.edu/markey-cancer-center/cancer-types/head-neck-cancer/salivary-gland-tumors

  Parotid glands are located in the cheeks in front of the ear and are the most common site for a salivary gland tumor. […] Markeys salivary gland tumor team provides expert consultation and ongoing care for patients with salivary gland tumors. […] Using state-of-the-art technology and leading-edge medical and surgical interventions, the salivary gland tumor team provides advanced and timely diagnosis and individualized, ongoing care for patients. Each patient is cared for by a team of specialists who meet regularly to discuss individual patient cases and treatment plans. This multidisciplinary team will work with you and your doctor to coordinate a care plan designed to offer the best outcomes. […] Clinical trials are research studies aimed at evaluating medical, surgical or behavioral interventions to determine if a new treatment is safe and effective. At Markey, we are advancing cancer care and research to prevent, detect and treat cancer one patient at a time. As a patient at Markey, you have a team of people looking at your individual case, applying the most recent cancer knowledge to give you the best chance of survival.

• #1 Salivary and Parotid Gland Cancer – UChicago Medicine

  https://www.uchicagomedicine.org/cancer/types-treatments/head-neck-cancers/salivary-and-parotid-gland-cancers

  Our head and neck surgical oncologists are experts at operating on the face and neck. Our primary goal is to remove the cancerous tumor, along with a small amount of tissue around it to prevent the cancer from coming back. […] Radiation therapy may be used to remove any remaining cancer cells after surgery. […] Some patients with salivary gland cancer, such as those with advanced or recurring cancers, may benefit from drug therapies, including novel therapies offered through clinical trials. […] Our speech pathologists, nutritionists and other rehabilitation team members get involved in your care from the very beginning and will work with you for months or years post-treatment. The goal is to reduce and reverse any treatment side effects.

• #2 Parotid Tumors Treatment – Parotid Tumor Surgery | Salivary Gland Surgery Los Angeles CA

  https://parotid.net/parotid-tumors/

  When learning about parotid tumors, it is important to know that the salivary gland system is comprised of the following structures: […] While neoplasm or tumor growth is possible in each of these structures, the parotid gland is the most frequent site of salivary gland tumor occurrence. Over 80% of all salivary gland tumors occur within the parotid gland. […] Tumors of the parotid gland can be separated into two main categories based on behavior, benign and malignant. […] Benign parotid tumors can however compress adjoining structures and cause dysfunction of surrounding structures based purely on their space occupying effects. […] While the word “benign” carries better connotations than more aggressive tumors, it is important to note that benign parotid tumors can undergo malignant transformation over time if not treated in a timely manner.

• #2 Parotid tumors – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/parotid-tumor/symptoms-causes/syc-20578986

  Parotid tumors are growths of cells that start in the parotid glands. […] Most parotid tumors aren’t cancerous. These are called noncancerous or benign parotid tumors. Sometimes the tumors are cancers. These are called malignant parotid tumors or parotid gland cancers. […] Diagnosis and treatment for parotid tumors is often done by doctors who specialize in problems that affect the ear, nose and throat. These doctors are called ENT specialists or otolaryngologists. […] Signs and symptoms of parotid tumors include: A lump or swelling on one side of the face that might appear near the ear or cheek. […] Make an appointment with a doctor or other healthcare professional if you have any symptoms that worry you.

• #2 Parotid tumors | Beacon Health System

  https://www.beaconhealthsystem.org/library/diseases-and-conditions/parotid-tumors?content_id=CON-20380680

  Parotid tumors often cause swelling in the face or jaw. Other symptoms include problems swallowing or a loss of facial movement. […] Diagnosis and treatment for parotid tumors is often done by doctors who specialize in problems that affect the ear, nose and throat. These doctors are called ENT specialists or otolaryngologists. […] Parotid tumor treatment often involves surgery to remove the tumor. If the tumor is cancerous, you might need more treatment. This could be with radiation therapy and chemotherapy. […] Operations used to remove parotid tumors include: Removing part of the parotid gland. For most parotid tumors, surgeons may cut away the tumor and some of the healthy parotid gland tissue around it. […] Surgery to remove all of the parotid gland is called parotidectomy. It might be needed for larger tumors, tumors that are cancerous and those that affect the deeper parts of the parotid gland.

• #2 Salivary Gland Neoplasms Treatment & Management: Medical Therapy, Surgical Therapy, Intraoperative Details

  https://emedicine.medscape.com/article/852373-treatment

  The histopathologic diagnosis of parotid masses is often unknown prior to surgery. Thus, the minimum procedure that should be performed for masses in the parotid gland is a superficial parotidectomy with identification and preservation of the facial nerve. The shift from enucleation, which was popular prior to 1950, to superficial parotidectomy as the minimal procedure for parotid tumors has substantially reduced recurrence rates for both benign and malignant disease. For benign pathology, this procedure is curative. By today’s standards, enucleation with incisional biopsies should never be performed. […] The specimen removed by superficial parotidectomy should be sent to the pathology department for frozen section analysis to intraoperatively determine whether a lesion is benign or malignant. Malignant diagnoses deserve special consideration.

• #2 Parotidectomy: Procedure Details, Recovery & Outlook

  https://my.clevelandclinic.org/health/treatments/24057-parotidectomy-parotid-gland-tumor-surgery

  Parotidectomy is surgery to remove all or part of a major salivary gland in your cheek called your parotid gland. You may need this surgery if a tumor forms in your parotid gland. Most tumors are benign (noncancerous), but they can be cancerous (malignant). Removing your parotid gland can prevent the tumor from damaging tissue or harming important nearby structures like your facial nerve. […] You may need a parotidectomy if a tumor has formed in your parotid gland. Usually, these tumors are benign (noncancerous), but malignant (cancerous) tumors may also develop. Both types typically need removed. […] Parotidectomy requires the expertise of a skilled surgeon who can identify and spare your facial nerve, which runs through your parotid gland. Your facial nerve controls the muscles that control the movement of your face. It allows you to smile, frown, wrinkle your forehead and express other emotions. Depending on your tumors location, it can be challenging to work around this nerve.

• #2 Parotidectomy (Parotid Gland Tumor Surgery) | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/salivary-gland/salivary-gland-cancer-treatment/parotidectomy-parotid-gland-tumor-surgery

  A parotidectomy requires tremendous precision on the part of your entire surgical team. In order to remove a parotid gland tumor, your surgeon will first need to locate and work around the facial nerve. […] The complete removal of your tumor, combined with the preservation of the facial nerve, is a priority of the surgical team at Memorial Sloan Kettering. […] In some cases, the facial nerve may be temporarily or, very rarely, permanently weakened due to removal of a parotid gland tumor. The risk of facial nerve weakness is directly related to the size, extent, and type of parotid gland tumor. […] Our reconstructive surgeons have developed highly specialized techniques for treating facial paralysis so patients with parotid gland tumors can regain movement after treatment. […] Loss of facial nerve function related to the treatment of a parotid gland tumor can result in partial or total paralysis on one side of the face. This can greatly impair a persons ability to make basic movements of the face, such as raising the eyebrows, closing the eyes, or smiling.

• #2 Childhood Salivary Gland Tumors Treatment (PDQ®) – NCI

  https://www.cancer.gov/types/head-and-neck/hp/child/salivary-gland-treatment-pdq

  Radical surgical removal is the treatment of choice for salivary gland tumors whenever possible, with additional use of radiation therapy for high-grade tumors or tumors that have invasive characteristics such as LNM, positive surgical margins, extracapsular extension, or perineural extension. […] Parotid gland tumors are removed with the aid of neurological monitoring to prevent damage to the facial nerve. […] Treatment options for childhood salivary gland tumors include the following: Surgery, Radiation therapy, Targeted therapy. […] In an international systematic review of 2,215 pediatric patients with malignant salivary tumors, 28.9% received surgery and radiation therapy, 1.8% received surgery, radiation therapy, and chemotherapy, and 0.2% received radiation therapy alone. […] One retrospective study compared proton therapy with conventional radiation therapy and found that proton therapy had a favorable acute toxicity and dosimetric profile.

• #2 Parotid tumors | UM Health-Sparrow

  https://www.uofmhealthsparrow.org/departments-conditions/conditions/parotid-tumors

  Radiation therapy is used to treat parotid gland cancers. Radiation therapy might be recommended after surgery. The radiation can kill any cancer cells that remain. If surgery isn’t possible, radiation therapy might be the first treatment for parotid cancers. […] Chemotherapy is sometimes used to treat parotid gland cancers. It might be needed if there’s a risk that the cancer might spread or if surgery isn’t an option. In these situations, chemotherapy might be done at the same time as radiation therapy.

• #2 Malignant Parotid Tumors: Practice Essentials, Anatomy, Diagnosis

  https://emedicine.medscape.com/article/1289616-overview

  If resectable, surgery is the primary modality of treatment for most malignant tumors of the parotid gland. General indications for postsurgical radiation therapy include tumors over 4 cm in greatest diameter, tumors of high grade, tumor invasion of local structures, lymphatic invasion, neural invasion, vascular invasion, tumor present very close to a nerve that was spared, tumors originating in or extending to the deep lobe, recurrent tumors following re-resection, positive margins on final pathology, and regional lymph node involvement.

• #2 Childhood Salivary Gland Tumors Treatment (PDQ®) – NCI

  https://www.cancer.gov/types/head-and-neck/hp/child/salivary-gland-treatment-pdq

  Another retrospective study used brachytherapy with iodine I 125 seeds to treat 24 children with mucoepidermoid carcinoma who had high-risk factors. […] Objective responses have been observed in all reported patients with recurrent NTRK fusionpositive MASC who were treated with entrectinib or larotrectinib. […] Ten of 11 adolescent or adult patients with TRK fusionpositive salivary gland tumors who were treated with larotrectinib experienced partial or complete responses.

• #2 Parotidectomy: Procedure Details, Recovery & Outlook

  https://my.clevelandclinic.org/health/treatments/24057-parotidectomy-parotid-gland-tumor-surgery

  A parotidectomy is surgery to remove all or part of your parotid gland. Talk to your healthcare provider about how surgery on your parotid gland will affect everyday activities, like eating and drinking, during recovery. Most people have to make adjustments to their daily routines after surgery. You may have to choose foods that are easy to chew and swallow. You may have to be less active. Depending on your surgery, you may have to get used to feeling less sensation in your face. Usually, these changes are temporary. Ask your provider what changes you should expect and how you can plan for them before getting a parotidectomy.

• #2 Nursing Teaching for Parotidectomy | Iowa Head and Neck Protocols

  https://medicine.uiowa.edu/iowaprotocols/nursing-teaching-parotidectomy

  Reassure that patient will be assessed frequently for pain. […] Pain medication will be administered intravenously on PRN basis while IV access is available. […] Oral pain medications will be available when patient is taking PO or when pain level no longer warrants IV medication. […] Patient/family will verbalize understanding of wound management. […] Describe location of incisions: will begin preauricularly and extend down to upper lateral neck. […] Closed wound drainage: Drain surgically placed under skin and attached to suction. […] Purpose: to facilitate healing by preventing fluid accumulation under skin flap. […] Duration: usually 2 to 4 days; discontinue when drainage decreases. […] Pressure dressing may be applied initially or possibly after drains removed. […] Suture line care is 2 to 4 times daily when dressing not in place; it is continued until sutures removed postoperative day 5 to 7.

• #2 Nursing Teaching for Parotidectomy | Iowa Head and Neck Protocols

  https://medicine.uiowa.edu/iowaprotocols/nursing-teaching-parotidectomy

  Patient will likely experience residual numbness of the cheek and earlobe. Reinforce safety measures to protect skin from injury: Use caution with heat-producing appliances such as hair dryers and hot rollers. […] Do not use hot water bottles or heating pads on this area. […] Use protective covering in cold weather to prevent frost bite. […] Use sunscreen (SPF 15 or greater) and protective covering to prevent sunburn. […] Use electric razor to avoid cutting skin. […] Encourage patient to express feelings regarding body image/sensory changes to nursing staff and other health care providers. […] Patient/family will verbalize understanding of home care instructions. […] Discharge instructions per handout B-19b1 Suture Line Care. […] Discharge instructions per handout B-19b1 Neck Dissection (if indicated)

• #2 5 innovative treatments for salivary gland cancer | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/salivary-gland-cancer/salivary-gland-cancer-treatment.html

  There are two main types of parotid gland surgery. The type of surgery a patient gets depends on whether the tumor is only in the glands superficial lobe or if it started in or has moved into the deep lobe. […] The goal of all parotid gland surgeries is to remove the tumor and preserve the function of the facial nerve. […] In addition, cancers of the parotid gland can spread into the skull base and grow along facial nerves. […] Most salivary gland surgery does not require any special reconstruction. […] These issues are addressed in each patients care plan. If the patient needs reconstructive surgery, that procedure usually takes place at the same time as the surgery to remove the tumor. […] Regular follow-up and screenings are vital due to the high risk of salivary gland returning. Patients need to see their doctors every three to six months for the first two years after treatment, since most cancers that recur, or come back, do so within that time. […] Salivary gland patients are also strongly urged not to smoke or drink alcohol during and after treatment. Drinking and smoking can make treatments less successful and worsen side effects during treatment. They can also greatly increase the chance of the cancer returning.

• #2 Salivary Gland | Head & Neck Surgery | Stanford Otolaryngology — Head & Neck Surgery (OHNS) | Stanford Medicine

  https://med.stanford.edu/ohns/OHNS-healthcare/head-and-neck-surgery/programs/salivary-gland-program.html

  During surgery sometimes the facial nerve may be sacrificed if the cancer is invading the nerve and reconstruction will take place during the same operation. […] The goals of the operation are to get the cancer and a cuff of normal tissue removed to achieve negative margin. […] Sometimes the lymph nodes of the neck are removed in a neck dissection to determine if your cancer has spread to the neck. […] Radiation therapy following surgery is needed in most cancers of the salivary gland. […] We offer complex facial nerve reconstruction to help the body restore function which usually takes over 1 year for the nerve to recover some function. […] The treatment is usually sialendoscopy. […] The diagnosis is made with ultrasound or CT scan. […] The treatment is usually sialendoscopy.

• #2 Salivary Gland Cancer | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/salivary-gland-cancer.html

  This team will include a surgical oncologist, radiation oncologist and medical oncologist. All specialize in treating salivary gland cancer, giving them an incredible amount of expertise to call upon when planning your care. […] Caring for salivary gland cancer patients at MD Anderson goes far beyond just eliminating the cancer. It includes maximizing your quality of life during and after treatment. Salivary gland cancer and its care may affect eating, hearing, speaking and appearance. […] You may get occupational, physical and speech therapy. If needed, you’ll have access to MD Anderson’s renowned reconstructive surgeons, as well as expert dental surgeons who can design and place custom-made dental implants. […] MD Anderson also offers dedicated survivorship care for salivary gland cancer patients. This care can help monitor for the disease’s return and offer interventions to maximize your quality of life. […] From support groups to counseling to integrative medicine care, we have all the services needed to treat not just the disease, but the whole person.

• #2 How A Parotid Tumor Affects Oral Health | Colgate®

  https://www.colgate.com/en-us/oral-health/cancer/how-a-parotid-tumor-affects-oral-health

  A parotid tumor diagnosis sounds scary, but keep in mind that they are often benign, and even when these tumors are malignant, they are treatable. Whether or not you’ve been diagnosed with a tumor, it’s essential that you practice good oral hygiene, eat a nutritious diet, and stay active to maintain a healthy lifestyle. Be sure to brush at least twice a day, and don’t forget to brush your tongue. Consider using helpful products like an antimicrobial mouth rinse and tongue scrapers. And be sure to see your dental professional for regular appointments. […] You may not avoid a medical issue as complex as a parotid tumor, but by taking good care of yourself, your body, and your glands will best be able to overcome the adverse effects of any disease you may contract. We wish you strength, love, and quick recovery – that will truly be something to smile about.

• #2 Ear Nose and Throat – Salivary Gland Tumors: Everything You Need To Know

  https://www.entlubbock.com/blog/salivary-gland-tumors/

  Salivary gland tumors grow slowly and can range greatly in size. Very small tumors may go unnoticed since they dont usually produce any symptoms. […] About 75% of salivary gland tumors in the parotid gland are benign. […] Treatment for salivary gland tumors generally involves the surgical removal of all or part of the affected salivary gland. […] For example, a superficial parotidectomy removes the 85% of the parotid gland that sits on top of (superficial to) the facial nerve, but not the 15% that sits below the facial nerve. Surgery to remove the entire gland is called a total parotidectomy. […] The good news is that most parotid tumors are diagnosed fairly early because of their obvious appearance. […] The outlook for patients diagnosed with salivary gland tumors is excellent in most cases. […] The key is to catch salivary gland tumors in a timely manner and treat them appropriately right away.

• #3 Nursing Teaching for Parotidectomy | Iowa Head and Neck Protocols

  https://medicine.uiowa.edu/iowaprotocols/nursing-teaching-parotidectomy

  Patient/family will verbalize understanding of IV. […] Necessary to administer fluids until oral intake is adequate. […] IV necessary to administer antibiotics as needed and to provide access for administration of analgesics and antiemetics. […] Patient/family will verbalize understanding of purpose and method of facial nerve assessment/ophthalmic care. […] Purpose: assess functioning of facial nerve and potential need for eye care. […] Instruct patient to report any eye irritation or foreign body sensation. […] Artificial tears or an ointment may be used to provide moisture to eye. […] Patient/family will verbalize understanding of potential occurrence of Frey’s syndrome. […] Patient may experience localized facial sweating and flushing over surgical site during mastication of food.

• #3 Parotidectomy (Parotid Gland Tumor Surgery) | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/salivary-gland/salivary-gland-cancer-treatment/parotidectomy-parotid-gland-tumor-surgery

  A parotidectomy requires tremendous precision on the part of your entire surgical team. In order to remove a parotid gland tumor, your surgeon will first need to locate and work around the facial nerve. […] The complete removal of your tumor, combined with the preservation of the facial nerve, is a priority of the surgical team at Memorial Sloan Kettering. […] In some cases, the facial nerve may be temporarily or, very rarely, permanently weakened due to removal of a parotid gland tumor. The risk of facial nerve weakness is directly related to the size, extent, and type of parotid gland tumor. […] Our reconstructive surgeons have developed highly specialized techniques for treating facial paralysis so patients with parotid gland tumors can regain movement after treatment. […] Loss of facial nerve function related to the treatment of a parotid gland tumor can result in partial or total paralysis on one side of the face. This can greatly impair a persons ability to make basic movements of the face, such as raising the eyebrows, closing the eyes, or smiling.

• #3 Salivary gland tumors | UK Healthcare

  https://ukhealthcare.uky.edu/markey-cancer-center/cancer-types/head-neck-cancer/salivary-gland-tumors

  Parotid glands are located in the cheeks in front of the ear and are the most common site for a salivary gland tumor. […] Markeys salivary gland tumor team provides expert consultation and ongoing care for patients with salivary gland tumors. […] Using state-of-the-art technology and leading-edge medical and surgical interventions, the salivary gland tumor team provides advanced and timely diagnosis and individualized, ongoing care for patients. Each patient is cared for by a team of specialists who meet regularly to discuss individual patient cases and treatment plans. This multidisciplinary team will work with you and your doctor to coordinate a care plan designed to offer the best outcomes. […] Clinical trials are research studies aimed at evaluating medical, surgical or behavioral interventions to determine if a new treatment is safe and effective. At Markey, we are advancing cancer care and research to prevent, detect and treat cancer one patient at a time. As a patient at Markey, you have a team of people looking at your individual case, applying the most recent cancer knowledge to give you the best chance of survival.

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