Materiały źródłowe

• #1 Preventive health measures in inflammatory bowel disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/

  We aim to review the literature and provide guidance on preventive health measures in inflammatory bowel disease (IBD). […] Preventive health measures can avert morbidity and improve the quality of life of patients with IBD. Gastroenterologists and primary care physicians (PCPs) should have an up to date working knowledge of preventive health measures for IBD patients. A holistic approach and better communication between gastroenterologists and PCPs with explicit clarification of roles will prevent duplication of services and streamline care. […] Effective preventive measures to reduce morbidity, hospitalization, and surgery are critical to improving disease free remission and quality of life. […] Studies have shown that IBD patients do not receive preventive services with the same thoroughness as other medical patients.

• #2 Can You Prevent Inflammatory Bowel Disease? | Mass General Brigham

  https://www.massgeneralbrigham.org/en/about/newsroom/articles/prevent-inflammatory-bowel-disease

  In recognition of World Inflammatory Bowel Disease (IBD) Day, Ashwin Ananthakrishnan, MBBS, MPH, answers patients most commonly searched questions about IBD prevention and treatment. […] Dr. Ananthakrishnan and other investigators at Mass Generals Center for the Study of Inflammatory Bowel Disease conduct cutting-edge research to identify new treatments and ways to prevent IBD. […] Theres no known way to prevent IBD. But there may be things you can do to help reduce your risk. […] To help reduce your risk of developing IBD: Avoid processed food and additives. Eat a Mediterranean-style diet rich in fruits and vegetables. Get enough sleep. Limit exposure to antibiotics. Dont smoke. Reduce stress and anxiety. […] Breastfeeding during infancy has been shown to reduce risk of IBD in children. Studies also have shown that people who exercise regularly may have a lower risk of developing IBD.

• #3 Preventive health measures in inflammatory bowel disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/

  We aim to review the literature and provide guidance on preventive health measures in inflammatory bowel disease (IBD). […] Preventive health measures can avert morbidity and improve the quality of life of patients with IBD. Gastroenterologists and primary care physicians (PCPs) should have an up to date working knowledge of preventive health measures for IBD patients. A holistic approach and better communication between gastroenterologists and PCPs with explicit clarification of roles will prevent duplication of services and streamline care. […] Effective preventive measures to reduce morbidity, hospitalization, and surgery are critical to improving disease free remission and quality of life. […] Studies have shown that IBD patients do not receive preventive services with the same thoroughness as other medical patients.

• #4 Preventive health measures in inflammatory bowel disease

  https://www.wjgnet.com/1007-9327/full/v22/i34/7625.htm

  Recent studies have suggested that IBD patients do not receive preventive services with the same thoroughness as patients with other chronic diseases. […] Therefore, gastroenterologists need to take a proactive role in the preventive health care needs of IBD patients by clarifying with each patient the limits of responsibility for preventive health and alerting PCPs to the unique health maintenance needs of IBD patients. […] This article reviews health interventions to prevent morbidity and mortality in IBD patients with emphasis on the location where such interventions are best delivered.

• #5 Preventive health measures in inflammatory bowel disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/

  We aim to review the literature and provide guidance on preventive health measures in inflammatory bowel disease (IBD). […] Preventive health measures can avert morbidity and improve the quality of life of patients with IBD. Gastroenterologists and primary care physicians (PCPs) should have an up to date working knowledge of preventive health measures for IBD patients. A holistic approach and better communication between gastroenterologists and PCPs with explicit clarification of roles will prevent duplication of services and streamline care. […] Effective preventive measures to reduce morbidity, hospitalization, and surgery are critical to improving disease free remission and quality of life. […] Studies have shown that IBD patients do not receive preventive services with the same thoroughness as other medical patients.

• #6 GUILD Conference

  https://www.healio.com/news/gastroenterology/20220223/avoid-ibd-complications-with-3tiered-preventive-care-approach

  It is critical to consider all aspects of preventive care in patients with inflammatory bowel disease to avoid serious infections or complications, according to a presenter at GUILD 2022. […] Long noted there are three forms of preventive care in IBD: primary prevention, which includes immunizations; secondary prevention, including early-disease detection through screening programs; and tertiary prevention, which includes managing long-term disease and disability to prevent further complications. […] Each of these forms of prevention needs to be addressed with our inflammatory bowel disease patients, Long said. […] Because patients with IBD are at an increased risk for both serious and opportunistic infections, we can address preventive aspects to try to prevent this, Long said. […] Please remember primary, secondary and tertiary prevention at the time of IBD diagnosis, Long said. Really think about things like initiating a medication for IBD to prevent downstream complications, that’s tertiary. Think about sunscreen, use vaccines, that’s primary; and then do appropriate secondary prevention screenings for your individual patient.

• #7 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro

  https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/

  Patients with inflammatory bowel disease (IBD) are subject to complications from the disease itself and also from the immunosuppressive therapies used for treatment. […] To optimize the care of patients with IBD, providers need to consider primary, secondary and tertiary prevention. […] Primary prevention is employed to prevent a disease or complication from developing, such as immunizations. […] Secondary prevention detects a disease early to prevent disability, such as through screening programs. […] Tertiary prevention employs measures to reduce the impact of long-term disease and disability. […] This review highlights methods of prevention that can be utilized in patients with IBD via partnership between the primary care and gastroenterology provider. […] Adherence to vaccination guidelines of inactivated vaccines can reduce these infectious complications.

• #8 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro

  https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/

  Therefore, patients with longstanding colonic inflammation should undergo routine colonoscopy starting at 8-10 years of colonic disease duration, with subsequent colonoscopy intervals based on the results. […] Screening for depression and anxiety is recommended in all patients with IBD. […] Therefore, by intervening early and treating inflammation, with a goal of mucosal healing, we can potentially prevent these morbid and potentially life-threatening, complications of IBD. […] This proactive approach of addressing primary, secondary and tertiary prevention in IBD patients can ultimately help to reduce infectious, malignant and long-term disease-related complications.

• #9 Inflammatory Bowel Disease (IBD): Lifestyle factors may aid prevention

  https://www.medicalnewstoday.com/articles/ibd-prevention-lifestyle-factors-inflammatory-bowel-disease-cases

  Inflammatory bowel disease is a chronic condition that can cause many unpleasant symptoms and damage the digestive tract. […] A recent study found that adherence to specific lifestyle factors may successfully prevent many inflammatory bowel disease cases. […] The exact cause of IBD is unknown, but researchers are continuing to study how lifestyle factors may play a role in IBD development and prevention. […] Researchers wanted to see whether IBD could be prevented by modifying certain lifestyle factors. […] Their analysis showed that low modifiable risk scores could prevent almost 43% of Crohns disease cases and over 44% of ulcerative colitis cases. […] Adherence to a healthy diet and lifestyle also could have prevented a substantial number of CD and UC cases. […] If our findings are true, this suggests that choosing low-risk or healthy dietary and lifestyle habits may be an effective strategy to prevent CD and UC.

• #10 Lifestyle factors for the prevention of inflammatory bowel disease | Gut

  https://gut.bmj.com/content/72/6/1093

  Objective To estimate the proportion of cases of Crohns disease (CD) and ulcerative colitis (UC) that could be prevented by modifiable lifestyle factors. […] Adherence to a low MRS could have prevented 42.9% (95% CI 12.2% to 66.1%) of CD and 44.4% (95% CI 9.0% to 69.8%) of UC cases. Similarly, adherence to a healthy lifestyle could have prevented 61.1% (95% CI 16.8% to 84.9%) of CD and 42.2% (95% CI 1.7% to 70.9%) of UC cases. […] Across six US and European cohorts, a substantial burden of inflammatory bowel diseases risk may be preventable through lifestyle modification.

• #11 Preventive health measures in inflammatory bowel disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/

  A diet rich in polyunsaturated fats and low in fiber may be associated with an increased risk of IBD. […] Patients with IBD are at increased risk of malnutrition via several mechanisms. […] Screening for anemia in IBD patients is recommended at least every 3 mo for outpatients with active disease, and once every 6 to 12 mo for patients in remission or with mild disease. […] The American Gastroenterological Association guidelines recommend DEXA screening in IBD patients with one or more risk factors. […] Preventive health care can avert morbidity, mortality, and reduce overall health care costs.

• #12 Selected Aspects of Nutrition in the Prevention and Treatment of Inflammatory Bowel Disease

  https://www.mdpi.com/2072-6643/14/23/4965

  Inflammatory bowel disease has become a global health problem at the turn of the 21st century. […] In this paper, the authors focus on the role of nutrition in the prevention of inflammatory bowel disease as well as on the available options to induce disease remission by means of dietary interventions such as exclusive and partial enteral nutrition in Crohn’s disease, the efficacy of which is reported to be comparable to that of steroid therapy. […] Diet is an easily modifiable factor affecting the prevalence of inflammatory bowel disease. […] The impact of breastfeeding on the reduced incidence of IBD has been proven in a number of studies. […] The Western diet, which is rich in animal proteins, saturated fats, and processed foods, is associated with an increase in the risk of inflammatory bowel disease, while the Mediterranean diet, which is a diet rich in fish, nuts, and fiber is associated with a decrease in this risk.

• #13 Can You Prevent Inflammatory Bowel Disease? | Mass General Brigham

  https://www.massgeneralbrigham.org/en/about/newsroom/articles/prevent-inflammatory-bowel-disease

  In recognition of World Inflammatory Bowel Disease (IBD) Day, Ashwin Ananthakrishnan, MBBS, MPH, answers patients most commonly searched questions about IBD prevention and treatment. […] Dr. Ananthakrishnan and other investigators at Mass Generals Center for the Study of Inflammatory Bowel Disease conduct cutting-edge research to identify new treatments and ways to prevent IBD. […] Theres no known way to prevent IBD. But there may be things you can do to help reduce your risk. […] To help reduce your risk of developing IBD: Avoid processed food and additives. Eat a Mediterranean-style diet rich in fruits and vegetables. Get enough sleep. Limit exposure to antibiotics. Dont smoke. Reduce stress and anxiety. […] Breastfeeding during infancy has been shown to reduce risk of IBD in children. Studies also have shown that people who exercise regularly may have a lower risk of developing IBD.

• #14 Selected Aspects of Nutrition in the Prevention and Treatment of Inflammatory Bowel Disease

  https://www.mdpi.com/2072-6643/14/23/4965

  Inflammatory bowel disease has become a global health problem at the turn of the 21st century. […] In this paper, the authors focus on the role of nutrition in the prevention of inflammatory bowel disease as well as on the available options to induce disease remission by means of dietary interventions such as exclusive and partial enteral nutrition in Crohn’s disease, the efficacy of which is reported to be comparable to that of steroid therapy. […] Diet is an easily modifiable factor affecting the prevalence of inflammatory bowel disease. […] The impact of breastfeeding on the reduced incidence of IBD has been proven in a number of studies. […] The Western diet, which is rich in animal proteins, saturated fats, and processed foods, is associated with an increase in the risk of inflammatory bowel disease, while the Mediterranean diet, which is a diet rich in fish, nuts, and fiber is associated with a decrease in this risk.

• #15 Lifestyle and diet if you have IBD – Mayo Clinic Health System

  https://www.mayoclinichealthsystem.org/hometown-health/speaking-of-health/lifestyle-and-diet-in-inflammatory-bowel-disease

  Inflammatory bowel disease, also known as IBD, consists of Crohn’s disease and ulcerative colitis. No specific food, diet or lifestyle causes, prevents or cures inflammatory bowel disease. And multiple factors can trigger the diagnosis. […] Your diet does not cause inflammatory bowel disease, or induce a flare. However, modifying your diet can manage symptoms during a flare. […] While several specialized diets may help certain patients, no plan has been proven to prevent or control inflammatory bowel disease, except for enteral nutrition, which is delivered in a nutrient-rich formula. […] Keeping a food diary is a great way to manage flare-ups. A dietitian specializing in inflammatory bowel disease may recommend a particular diet based on your symptoms. […] Be careful with vitamins and mineral supplements. Remember, most of your needed vitamins are obtained by eating a balanced diet. Some over-the-counter supplements can contain lactose, starch and other ingredients that can worsen your symptoms.

• #16 Selected Aspects of Nutrition in the Prevention and Treatment of Inflammatory Bowel Disease

  https://www.mdpi.com/2072-6643/14/23/4965

  Exclusive enteral nutrition (EEN) is the best-tested approach to nutritional management aimed at inducing remission in mild and moderate Crohn’s disease. […] The high efficacy of exclusive enteral nutrition in terms of achieving remission of Crohn’s disease in the pediatric population encourages the use of this approach in the adult population. […] The efficacy of the Crohn’s disease exclusion diet was also demonstrated in a population of adult subjects by Szczubełek et al.

• #17

  https://link.springer.com/article/10.1007/s10389-024-02278-z

  This study aimed to assess the potential role of physical activity (PA) in reducing the risk of developing inflammatory bowel diseases (IBDs) and in their management. […] PA seems to be effective in preventing or treating IBDs and their complications. […] The preventive role of PA towards IBD is considered to a lesser extent than the therapeutic one. […] In fact, even if the biological process is not yet elucidated, it seems that the lack of PA can determine a shift of the balance between pro-inflammatory and anti-inflammatory mechanisms responsible for the alteration of immune responses developed by the patients. […] The results of the present systematic review suggest that PA could be considered a useful factor both for preventing and managing IBDs. […] In particular, the available literature shows that PA may represent a preventive factor towards the development of these diseases.

• #18 Preventive health measures in inflammatory bowel disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/

  Therefore, gastroenterologists need to take a proactive role in the preventive health care needs of IBD patients by clarifying with each patient the limits of responsibility for preventive health and alerting PCPs to the unique health maintenance needs of IBD patients. […] This article reviews health interventions to prevent morbidity and mortality in IBD patients with emphasis on the location where such interventions are best delivered. […] Smoking cessation is an important goal of therapy in patients with CD. […] Smoking cessation should be strongly advocated by gastroenterologists and PCPs in all CD patients that are current smokers because patients who quit smoking have a reduced number of relapses compared to continuing smokers. […] Physical activity improves quality of life without detrimental effect on disease activity; it may also increase muscle mass and prevent osteoporosis.

• #19 Preventive health measures in inflammatory bowel disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/

  Therefore, gastroenterologists need to take a proactive role in the preventive health care needs of IBD patients by clarifying with each patient the limits of responsibility for preventive health and alerting PCPs to the unique health maintenance needs of IBD patients. […] This article reviews health interventions to prevent morbidity and mortality in IBD patients with emphasis on the location where such interventions are best delivered. […] Smoking cessation is an important goal of therapy in patients with CD. […] Smoking cessation should be strongly advocated by gastroenterologists and PCPs in all CD patients that are current smokers because patients who quit smoking have a reduced number of relapses compared to continuing smokers. […] Physical activity improves quality of life without detrimental effect on disease activity; it may also increase muscle mass and prevent osteoporosis.

• #20 Crohn’s Disease: Diagnosis and Management | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/1201/p661.html

  Crohn’s disease is a chronic inflammatory condition that affects the gastrointestinal tract. […] All patients with Crohn’s disease should be counseled on smoking avoidance or cessation. […] Smoking cessation reduces complications experienced by patients with Crohn’s disease, and all patients should be counseled not to smoke and offered cessation assistance. […] Maximizing prevention measures is essential in caring for these patients. […] Preventive measures can mitigate these complications. Patients with Crohn’s disease are at increased risk of cancer, osteoporosis, anemia, nutritional deficiencies, depression, infection, and thrombotic events. […] After surgical resection, prophylactic therapy should be considered to prevent recurrence. […] Current data show that anti-TNF agents are most effective. […] Nitroimidazole antibiotics (metronidazole), mesalamine, and thiopurines are also useful in preventing postoperative recurrence.

• #21 Can You Prevent Inflammatory Bowel Disease? | Mass General Brigham

  https://www.massgeneralbrigham.org/en/about/newsroom/articles/prevent-inflammatory-bowel-disease

  In recognition of World Inflammatory Bowel Disease (IBD) Day, Ashwin Ananthakrishnan, MBBS, MPH, answers patients most commonly searched questions about IBD prevention and treatment. […] Dr. Ananthakrishnan and other investigators at Mass Generals Center for the Study of Inflammatory Bowel Disease conduct cutting-edge research to identify new treatments and ways to prevent IBD. […] Theres no known way to prevent IBD. But there may be things you can do to help reduce your risk. […] To help reduce your risk of developing IBD: Avoid processed food and additives. Eat a Mediterranean-style diet rich in fruits and vegetables. Get enough sleep. Limit exposure to antibiotics. Dont smoke. Reduce stress and anxiety. […] Breastfeeding during infancy has been shown to reduce risk of IBD in children. Studies also have shown that people who exercise regularly may have a lower risk of developing IBD.

• #22 Inflammatory Bowel Disease Treatment | Gastro MD

  https://gastro-md.com/specialties/intestine-colon-conditions/inflammatory-bowel-disease/

  Eat smaller, more frequent meals: Consuming smaller, more frequent meals throughout the day, rather than two or three large meals, may help reduce stress on the digestive system and decrease symptoms. […] Stay hydrated: Drink plenty of water throughout the day to stay hydrated, particularly during flare-ups, when diarrhea can lead to dehydration. […] Manage stress: Stress can exacerbate IBD symptoms. Incorporate stress-reduction techniques into your daily routine, such as deep breathing, meditation, yoga, or mindfulness practices. […] Exercise regularly: Engage in regular physical activity to help maintain a healthy weight, reduce stress, and support overall well-being. Consult your doctor to develop an exercise plan tailored to your needs and limitations. […] Quit smoking: Smoking has been linked to an increased risk of Crohns disease and can worsen symptoms. Quitting smoking is an essential step in managing IBD and promoting overall health.

• #23 Health Maintenance for Adult Patients with Inflammatory Bowel Disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8608358/

  Vaccines are important for the prevention of a number of infectious illnesses. […] Among patients with IBD, it is very important to make sure that patients have received their age-appropriate vaccines ideally prior to initiation of immunosuppressive medications for optimal immune response. […] Required vaccinations should be given to all patients with IBD whenever possible. It is very important for gastroenterologists to vaccinate their patients with IBD early on prior to initiation of immunosuppression to achieve a maximum immune response. […] Patients with IBD are at an increased risk for developing pneumococcal pneumonia compared to the general population. […] Patients with IBD are at increased risk for the development of herpes zoster compared to the general population, and those receiving immunosuppression, especially tofacitinib, are at a further increased risk.

• #24 Health Maintenance for Adult Patients with Inflammatory Bowel Disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8608358/

  Vaccines are important for the prevention of a number of infectious illnesses. […] Among patients with IBD, it is very important to make sure that patients have received their age-appropriate vaccines ideally prior to initiation of immunosuppressive medications for optimal immune response. […] Required vaccinations should be given to all patients with IBD whenever possible. It is very important for gastroenterologists to vaccinate their patients with IBD early on prior to initiation of immunosuppression to achieve a maximum immune response. […] Patients with IBD are at an increased risk for developing pneumococcal pneumonia compared to the general population. […] Patients with IBD are at increased risk for the development of herpes zoster compared to the general population, and those receiving immunosuppression, especially tofacitinib, are at a further increased risk.

• #25 Health Maintenance for Adult Patients with Inflammatory Bowel Disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8608358/

  Vaccines are important for the prevention of a number of infectious illnesses. […] Among patients with IBD, it is very important to make sure that patients have received their age-appropriate vaccines ideally prior to initiation of immunosuppressive medications for optimal immune response. […] Required vaccinations should be given to all patients with IBD whenever possible. It is very important for gastroenterologists to vaccinate their patients with IBD early on prior to initiation of immunosuppression to achieve a maximum immune response. […] Patients with IBD are at an increased risk for developing pneumococcal pneumonia compared to the general population. […] Patients with IBD are at increased risk for the development of herpes zoster compared to the general population, and those receiving immunosuppression, especially tofacitinib, are at a further increased risk.

• #26 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro

  https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/

  Annual influenza vaccination is indicated in all patients with IBD, pneumococcal vaccination series is indicated in all immunosuppressed patients with IBD and herpes zoster vaccination is indicated in all patients with IBD 50 years of age. […] Another method of primary prevention in IBD patients is sunscreen use to prevent skin cancer. […] Therefore, this is a potentially preventable complication of therapy through broad-spectrum sunscreen use. […] Finally, weight bearing exercise and calcium/ vitamin D supplementation, when appropriate, can prevent downstream osteoporotic fracture in these patients who may require recurrent courses of corticosteroids during their lifetimes with IBD. […] Therefore, a dermatology skin screening program is recommended in all patients with IBD. […] Annual cervical cancer screening is recommended in patients with IBD on immunosuppression.

• #27 Health Maintenance for Adult Patients with Inflammatory Bowel Disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8608358/

  Vaccines are important for the prevention of a number of infectious illnesses. […] Among patients with IBD, it is very important to make sure that patients have received their age-appropriate vaccines ideally prior to initiation of immunosuppressive medications for optimal immune response. […] Required vaccinations should be given to all patients with IBD whenever possible. It is very important for gastroenterologists to vaccinate their patients with IBD early on prior to initiation of immunosuppression to achieve a maximum immune response. […] Patients with IBD are at an increased risk for developing pneumococcal pneumonia compared to the general population. […] Patients with IBD are at increased risk for the development of herpes zoster compared to the general population, and those receiving immunosuppression, especially tofacitinib, are at a further increased risk.

• #28 Health Maintenance for Adult Patients with Inflammatory Bowel Disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8608358/

  Vaccines are important for the prevention of a number of infectious illnesses. […] Among patients with IBD, it is very important to make sure that patients have received their age-appropriate vaccines ideally prior to initiation of immunosuppressive medications for optimal immune response. […] Required vaccinations should be given to all patients with IBD whenever possible. It is very important for gastroenterologists to vaccinate their patients with IBD early on prior to initiation of immunosuppression to achieve a maximum immune response. […] Patients with IBD are at an increased risk for developing pneumococcal pneumonia compared to the general population. […] Patients with IBD are at increased risk for the development of herpes zoster compared to the general population, and those receiving immunosuppression, especially tofacitinib, are at a further increased risk.

• #29 Health Maintenance for Adult Patients with Inflammatory Bowel Disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8608358/

  Vaccines are important for the prevention of a number of infectious illnesses. […] Among patients with IBD, it is very important to make sure that patients have received their age-appropriate vaccines ideally prior to initiation of immunosuppressive medications for optimal immune response. […] Required vaccinations should be given to all patients with IBD whenever possible. It is very important for gastroenterologists to vaccinate their patients with IBD early on prior to initiation of immunosuppression to achieve a maximum immune response. […] Patients with IBD are at an increased risk for developing pneumococcal pneumonia compared to the general population. […] Patients with IBD are at increased risk for the development of herpes zoster compared to the general population, and those receiving immunosuppression, especially tofacitinib, are at a further increased risk.

• #30 Chemoprevention of Colitis-Associated Dysplasia or Cancer in Inflammatory Bowel Disease

  https://www.gutnliver.org/journal/view.html?volume=16&number=6&spage=840

  The association between inflammatory bowel disease and colorectal cancer is well known. Although the overall incidence of inflammatory bowel disease has declined recently, patients with this disease still have a 1.7-fold increased risk of colorectal cancer. The risk factors for developing colorectal cancer include extensive colitis, young age at diagnosis, disease duration, primary sclerosing cholangitis, chronic colonic mucosal inflammation, dysplasia lesion, and post-inflammatory polyps. In patients with inflammatory bowel disease, control of chronic inflammation and surveillance colonoscopies are important for the prevention of colorectal cancer. The 2017 guidelines from the European Crohns and Colitis Organisation suggest that colonoscopies to screen for colorectal cancer should be performed when inflammatory bowel disease symptoms have lasted for 8 years. Current evidence supports the use of chemoprevention therapy with mesalamine to reduce the risk of colorectal cancer in patients with ulcerative colitis. Other compounds, including thiopurine, folic acid, statin, and tumor necrosis factor- inhibitor, are controversial. Large surveillance cohort studies with longer follow-up duration are needed to evaluate the impact of drugs on colorectal cancer risks.

• #31 Chemoprevention of Colitis-Associated Dysplasia or Cancer in Inflammatory Bowel Disease

  https://www.gutnliver.org/journal/view.html?volume=16&number=6&spage=840

  The association between inflammatory bowel disease and colorectal cancer is well known. Although the overall incidence of inflammatory bowel disease has declined recently, patients with this disease still have a 1.7-fold increased risk of colorectal cancer. The risk factors for developing colorectal cancer include extensive colitis, young age at diagnosis, disease duration, primary sclerosing cholangitis, chronic colonic mucosal inflammation, dysplasia lesion, and post-inflammatory polyps. In patients with inflammatory bowel disease, control of chronic inflammation and surveillance colonoscopies are important for the prevention of colorectal cancer. The 2017 guidelines from the European Crohns and Colitis Organisation suggest that colonoscopies to screen for colorectal cancer should be performed when inflammatory bowel disease symptoms have lasted for 8 years. Current evidence supports the use of chemoprevention therapy with mesalamine to reduce the risk of colorectal cancer in patients with ulcerative colitis. Other compounds, including thiopurine, folic acid, statin, and tumor necrosis factor- inhibitor, are controversial. Large surveillance cohort studies with longer follow-up duration are needed to evaluate the impact of drugs on colorectal cancer risks.

• #32 Chemoprevention of Colitis-Associated Dysplasia or Cancer in Inflammatory Bowel Disease

  https://www.gutnliver.org/journal/view.html?volume=16&number=6&spage=840

  Controlled chronic inflammation and surveillance colonoscopy are important for the prevention of CRC in IBD patients. According to the 2017 ECCO consensus, the first colonoscopy should be scheduled 8 years after the onset of symptoms, and the next surveillance should be scheduled in 1 to 5 years according to the risk factors. Current evidence supports chemoprevention with mesalamine to reduce CRC among UC patients. Other compounds, including thiopurine, folic acid, statins, and TNF- inhibitors, are controversial. An RCT to investigate the effects of chemoprevention is not feasible and would be unethical. However, large surveillance cohort studies with longer follow-up times are required to evaluate the impact of drugs on CRC risks.

• #33 Health Maintenance for Adult Patients with Inflammatory Bowel Disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8608358/

  Patients with IBD who are receiving immunosuppression are at a 30% increased risk for cervical neoplasia compared to the general population. […] All patients with IBD, regardless of their disease subtype, should be encouraged to stop smoking due to the negative effect of tobacco smoking on their general well-being and the increased risk for many malignancies including lung and colon cancer. […] It is critical to screen patients with IBD for anxiety and depression especially since depressive severity was found to be a risk factor for suicidal ideation among these patients. […] Staying up-to-date with health care maintenance of patients with IBD is critical, especially given the increased risk for vaccine-preventable infections as well as comorbidities such as malignancies, bone, and mood disorders.

• #34 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro

  https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/

  Annual influenza vaccination is indicated in all patients with IBD, pneumococcal vaccination series is indicated in all immunosuppressed patients with IBD and herpes zoster vaccination is indicated in all patients with IBD 50 years of age. […] Another method of primary prevention in IBD patients is sunscreen use to prevent skin cancer. […] Therefore, this is a potentially preventable complication of therapy through broad-spectrum sunscreen use. […] Finally, weight bearing exercise and calcium/ vitamin D supplementation, when appropriate, can prevent downstream osteoporotic fracture in these patients who may require recurrent courses of corticosteroids during their lifetimes with IBD. […] Therefore, a dermatology skin screening program is recommended in all patients with IBD. […] Annual cervical cancer screening is recommended in patients with IBD on immunosuppression.

• #35 Preventive health measures in inflammatory bowel disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/

  A diet rich in polyunsaturated fats and low in fiber may be associated with an increased risk of IBD. […] Patients with IBD are at increased risk of malnutrition via several mechanisms. […] Screening for anemia in IBD patients is recommended at least every 3 mo for outpatients with active disease, and once every 6 to 12 mo for patients in remission or with mild disease. […] The American Gastroenterological Association guidelines recommend DEXA screening in IBD patients with one or more risk factors. […] Preventive health care can avert morbidity, mortality, and reduce overall health care costs.

• #36 Preventive health measures in inflammatory bowel disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/

  A diet rich in polyunsaturated fats and low in fiber may be associated with an increased risk of IBD. […] Patients with IBD are at increased risk of malnutrition via several mechanisms. […] Screening for anemia in IBD patients is recommended at least every 3 mo for outpatients with active disease, and once every 6 to 12 mo for patients in remission or with mild disease. […] The American Gastroenterological Association guidelines recommend DEXA screening in IBD patients with one or more risk factors. […] Preventive health care can avert morbidity, mortality, and reduce overall health care costs.

• #37 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro

  https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/

  Annual influenza vaccination is indicated in all patients with IBD, pneumococcal vaccination series is indicated in all immunosuppressed patients with IBD and herpes zoster vaccination is indicated in all patients with IBD 50 years of age. […] Another method of primary prevention in IBD patients is sunscreen use to prevent skin cancer. […] Therefore, this is a potentially preventable complication of therapy through broad-spectrum sunscreen use. […] Finally, weight bearing exercise and calcium/ vitamin D supplementation, when appropriate, can prevent downstream osteoporotic fracture in these patients who may require recurrent courses of corticosteroids during their lifetimes with IBD. […] Therefore, a dermatology skin screening program is recommended in all patients with IBD. […] Annual cervical cancer screening is recommended in patients with IBD on immunosuppression.

• #38 Health Maintenance for Adult Patients with Inflammatory Bowel Disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8608358/

  Patients with IBD who are receiving immunosuppression are at a 30% increased risk for cervical neoplasia compared to the general population. […] All patients with IBD, regardless of their disease subtype, should be encouraged to stop smoking due to the negative effect of tobacco smoking on their general well-being and the increased risk for many malignancies including lung and colon cancer. […] It is critical to screen patients with IBD for anxiety and depression especially since depressive severity was found to be a risk factor for suicidal ideation among these patients. […] Staying up-to-date with health care maintenance of patients with IBD is critical, especially given the increased risk for vaccine-preventable infections as well as comorbidities such as malignancies, bone, and mood disorders.

• #39 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro

  https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/

  Therefore, patients with longstanding colonic inflammation should undergo routine colonoscopy starting at 8-10 years of colonic disease duration, with subsequent colonoscopy intervals based on the results. […] Screening for depression and anxiety is recommended in all patients with IBD. […] Therefore, by intervening early and treating inflammation, with a goal of mucosal healing, we can potentially prevent these morbid and potentially life-threatening, complications of IBD. […] This proactive approach of addressing primary, secondary and tertiary prevention in IBD patients can ultimately help to reduce infectious, malignant and long-term disease-related complications.

• #40 Chemoprevention of Colitis-Associated Dysplasia or Cancer in Inflammatory Bowel Disease

  https://www.gutnliver.org/journal/view.html?volume=16&number=6&spage=840

  The association between inflammatory bowel disease and colorectal cancer is well known. Although the overall incidence of inflammatory bowel disease has declined recently, patients with this disease still have a 1.7-fold increased risk of colorectal cancer. The risk factors for developing colorectal cancer include extensive colitis, young age at diagnosis, disease duration, primary sclerosing cholangitis, chronic colonic mucosal inflammation, dysplasia lesion, and post-inflammatory polyps. In patients with inflammatory bowel disease, control of chronic inflammation and surveillance colonoscopies are important for the prevention of colorectal cancer. The 2017 guidelines from the European Crohns and Colitis Organisation suggest that colonoscopies to screen for colorectal cancer should be performed when inflammatory bowel disease symptoms have lasted for 8 years. Current evidence supports the use of chemoprevention therapy with mesalamine to reduce the risk of colorectal cancer in patients with ulcerative colitis. Other compounds, including thiopurine, folic acid, statin, and tumor necrosis factor- inhibitor, are controversial. Large surveillance cohort studies with longer follow-up duration are needed to evaluate the impact of drugs on colorectal cancer risks.

• #41 Chemoprevention of Colitis-Associated Dysplasia or Cancer in Inflammatory Bowel Disease

  https://www.gutnliver.org/journal/view.html?volume=16&number=6&spage=840

  Controlled chronic inflammation and surveillance colonoscopy are important for the prevention of CRC in IBD patients. According to the 2017 ECCO consensus, the first colonoscopy should be scheduled 8 years after the onset of symptoms, and the next surveillance should be scheduled in 1 to 5 years according to the risk factors. Current evidence supports chemoprevention with mesalamine to reduce CRC among UC patients. Other compounds, including thiopurine, folic acid, statins, and TNF- inhibitors, are controversial. An RCT to investigate the effects of chemoprevention is not feasible and would be unethical. However, large surveillance cohort studies with longer follow-up times are required to evaluate the impact of drugs on CRC risks.

• #42 Crohn’s Disease: Diagnosis and Management | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/1201/p661.html

  Crohn’s disease is a chronic inflammatory condition that affects the gastrointestinal tract. […] All patients with Crohn’s disease should be counseled on smoking avoidance or cessation. […] Smoking cessation reduces complications experienced by patients with Crohn’s disease, and all patients should be counseled not to smoke and offered cessation assistance. […] Maximizing prevention measures is essential in caring for these patients. […] Preventive measures can mitigate these complications. Patients with Crohn’s disease are at increased risk of cancer, osteoporosis, anemia, nutritional deficiencies, depression, infection, and thrombotic events. […] After surgical resection, prophylactic therapy should be considered to prevent recurrence. […] Current data show that anti-TNF agents are most effective. […] Nitroimidazole antibiotics (metronidazole), mesalamine, and thiopurines are also useful in preventing postoperative recurrence.

• #43 International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease | Nature Reviews Gastroenterology & Hepatology

  https://www.nature.com/articles/s41575-021-00492-8

  Patients with inflammatory bowel disease (IBD) are at increased risk of thrombotic events. […] The aims of this Evidence-Based Guideline were to summarize available evidence and to provide practical recommendations regarding epidemiological aspects, prevention and drug-related risks of venous and arterial thrombotic events in patients with IBD. […] Thromboprophylaxis is indicated during hospitalization of any cause in patients with IBD. […] Disease activity is a modifiable risk factor in patients with IBD, and physicians should aim to achieve deep remission to reduce the risk. […] Exposure to steroids should be limited. […] Antitumour necrosis factor agents might be associated with a reduced risk of thrombotic events. […] Control of disease activity is an important factor in reducing the risk of venous and arterial thrombotic events in patients with IBD.

• #44 International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease | Nature Reviews Gastroenterology & Hepatology

  https://www.nature.com/articles/s41575-021-00492-8

  Patients with inflammatory bowel disease (IBD) are at increased risk of thrombotic events. […] The aims of this Evidence-Based Guideline were to summarize available evidence and to provide practical recommendations regarding epidemiological aspects, prevention and drug-related risks of venous and arterial thrombotic events in patients with IBD. […] Thromboprophylaxis is indicated during hospitalization of any cause in patients with IBD. […] Disease activity is a modifiable risk factor in patients with IBD, and physicians should aim to achieve deep remission to reduce the risk. […] Exposure to steroids should be limited. […] Antitumour necrosis factor agents might be associated with a reduced risk of thrombotic events. […] Control of disease activity is an important factor in reducing the risk of venous and arterial thrombotic events in patients with IBD.

• #45 International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease | Nature Reviews Gastroenterology & Hepatology

  https://www.nature.com/articles/s41575-021-00492-8

  Patients with inflammatory bowel disease (IBD) are at increased risk of thrombotic events. […] The aims of this Evidence-Based Guideline were to summarize available evidence and to provide practical recommendations regarding epidemiological aspects, prevention and drug-related risks of venous and arterial thrombotic events in patients with IBD. […] Thromboprophylaxis is indicated during hospitalization of any cause in patients with IBD. […] Disease activity is a modifiable risk factor in patients with IBD, and physicians should aim to achieve deep remission to reduce the risk. […] Exposure to steroids should be limited. […] Antitumour necrosis factor agents might be associated with a reduced risk of thrombotic events. […] Control of disease activity is an important factor in reducing the risk of venous and arterial thrombotic events in patients with IBD.

• #46 International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease | Nature Reviews Gastroenterology & Hepatology

  https://www.nature.com/articles/s41575-021-00492-8

  Patients with inflammatory bowel disease (IBD) are at increased risk of thrombotic events. […] The aims of this Evidence-Based Guideline were to summarize available evidence and to provide practical recommendations regarding epidemiological aspects, prevention and drug-related risks of venous and arterial thrombotic events in patients with IBD. […] Thromboprophylaxis is indicated during hospitalization of any cause in patients with IBD. […] Disease activity is a modifiable risk factor in patients with IBD, and physicians should aim to achieve deep remission to reduce the risk. […] Exposure to steroids should be limited. […] Antitumour necrosis factor agents might be associated with a reduced risk of thrombotic events. […] Control of disease activity is an important factor in reducing the risk of venous and arterial thrombotic events in patients with IBD.

• #47 International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease | Nature Reviews Gastroenterology & Hepatology

  https://www.nature.com/articles/s41575-021-00492-8

  Established cardiovascular disease risk factors should be actively investigated and controlled in patients with IBD. […] Thromboprophylaxis should be given to patients with IBD during hospitalization of any cause. Low molecular weight heparin or fondaparinux is recommended over low-dose unfractionated heparin. […] Thromboprophylaxis should be considered in ambulatory patients with active IBD with known risk factors for VTE and maintained until the patient is in remission. […] Thromboprophylaxis does not increase the risk of further IBD-related gastrointestinal bleeding in patients with active disease.

• #48 International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease | Nature Reviews Gastroenterology & Hepatology

  https://www.nature.com/articles/s41575-021-00492-8

  Established cardiovascular disease risk factors should be actively investigated and controlled in patients with IBD. […] Thromboprophylaxis should be given to patients with IBD during hospitalization of any cause. Low molecular weight heparin or fondaparinux is recommended over low-dose unfractionated heparin. […] Thromboprophylaxis should be considered in ambulatory patients with active IBD with known risk factors for VTE and maintained until the patient is in remission. […] Thromboprophylaxis does not increase the risk of further IBD-related gastrointestinal bleeding in patients with active disease.

• #49 Targeting Disease Prediction and Prevention: the New Frontier in IBD

  https://reports.mountsinai.org/article/gi2023-04-targeting-ibd-prediction-and-prevention

  Mount Sinai researchers have found strong evidence that before the first symptoms of Crohns disease and ulcerative colitis occur, theres a preclinical phase in which immune and inflammatory pathways are already altered. By targeting and treating the early pathogenic events that promote IBD development, they believe, disease onset could be prevented or impeded. […] In other words, by targeting and treating the early pathogenic events that promote IBD development, disease onset could be prevented or impeded, and a true opportunity to change its course revealed. […] Being able to identify in the blood or stool those dysregulated pathways through biomarkers, such as proteomics, metabolomics, gut microbiome, and antimicrobial antibodies, will lead to the development of prediction models and prevention strategies. […] If were going to find a way to prevent Crohns disease and ulcerative colitis, it will require the global GI community actively embracing this new paradigm of prediction and prevention, declares Dr. Colombel.

• #50 Targeting Disease Prediction and Prevention: the New Frontier in IBD

  https://reports.mountsinai.org/article/gi2023-04-targeting-ibd-prediction-and-prevention

  Mount Sinai researchers have found strong evidence that before the first symptoms of Crohns disease and ulcerative colitis occur, theres a preclinical phase in which immune and inflammatory pathways are already altered. By targeting and treating the early pathogenic events that promote IBD development, they believe, disease onset could be prevented or impeded. […] In other words, by targeting and treating the early pathogenic events that promote IBD development, disease onset could be prevented or impeded, and a true opportunity to change its course revealed. […] Being able to identify in the blood or stool those dysregulated pathways through biomarkers, such as proteomics, metabolomics, gut microbiome, and antimicrobial antibodies, will lead to the development of prediction models and prevention strategies. […] If were going to find a way to prevent Crohns disease and ulcerative colitis, it will require the global GI community actively embracing this new paradigm of prediction and prevention, declares Dr. Colombel.

• #51 Targeting Disease Prediction and Prevention: the New Frontier in IBD

  https://reports.mountsinai.org/article/gi2023-04-targeting-ibd-prediction-and-prevention

  Mount Sinai researchers have found strong evidence that before the first symptoms of Crohns disease and ulcerative colitis occur, theres a preclinical phase in which immune and inflammatory pathways are already altered. By targeting and treating the early pathogenic events that promote IBD development, they believe, disease onset could be prevented or impeded. […] In other words, by targeting and treating the early pathogenic events that promote IBD development, disease onset could be prevented or impeded, and a true opportunity to change its course revealed. […] Being able to identify in the blood or stool those dysregulated pathways through biomarkers, such as proteomics, metabolomics, gut microbiome, and antimicrobial antibodies, will lead to the development of prediction models and prevention strategies. […] If were going to find a way to prevent Crohns disease and ulcerative colitis, it will require the global GI community actively embracing this new paradigm of prediction and prevention, declares Dr. Colombel.

• #52 Is Prevention Achievable in Inflammatory Bowel Disease? – Helmsley Charitable Trust

  https://helmsleytrust.org/news-and-insights/is-prevention-achievable-in-inflammatory-bowel-disease/

  The preclinical phase of Crohns disease is what happens before the first symptoms occur and the diagnosis is made. […] If this preclinical period can be diagnosed, different prediction tools could be offered to individuals at risk for developing IBD, with the goal of eventually offering prevention strategies. […] The ultimate goal of our studies is to build a predictive tool that can be applied to people at risk of Crohns disease, such as first-degree relatives of patients with Crohns disease, and then to start the first prevention trial. […] So, what we are learning in the preclinical phase may be very useful for new therapeutics in later phases as well.

• #53 Inflammatory Bowel Disease Treatment | Gastro MD

  https://gastro-md.com/specialties/intestine-colon-conditions/inflammatory-bowel-disease/

  Inflammatory bowel disease (IBD), which includes Crohns disease and ulcerative colitis, is a complex and chronic condition with no known cure. Some lifestyle changes and strategies may help manage symptoms, reduce the risk of flare-ups, and promote overall gut health. Here are some prevention tips for IBD: […] Eat a balanced diet: Focus on consuming a well-rounded diet rich in fruits, vegetables, lean proteins, and whole grains. While there is no specific diet for IBD, a balanced diet can help maintain overall health and support gut function. Keep a food diary to help identify foods that may worsen your IBD symptoms. Common trigger foods include high-fat or fried foods, spicy foods, dairy products, and high-fiber foods. Once identified, limit or avoid these foods to reduce the risk of flare-ups.

• #54 Inflammatory Bowel Disease Treatment | Gastro MD

  https://gastro-md.com/specialties/intestine-colon-conditions/inflammatory-bowel-disease/

  Eat smaller, more frequent meals: Consuming smaller, more frequent meals throughout the day, rather than two or three large meals, may help reduce stress on the digestive system and decrease symptoms. […] Stay hydrated: Drink plenty of water throughout the day to stay hydrated, particularly during flare-ups, when diarrhea can lead to dehydration. […] Manage stress: Stress can exacerbate IBD symptoms. Incorporate stress-reduction techniques into your daily routine, such as deep breathing, meditation, yoga, or mindfulness practices. […] Exercise regularly: Engage in regular physical activity to help maintain a healthy weight, reduce stress, and support overall well-being. Consult your doctor to develop an exercise plan tailored to your needs and limitations. […] Quit smoking: Smoking has been linked to an increased risk of Crohns disease and can worsen symptoms. Quitting smoking is an essential step in managing IBD and promoting overall health.

• #55 Inflammatory Bowel Disease Treatment | Gastro MD

  https://gastro-md.com/specialties/intestine-colon-conditions/inflammatory-bowel-disease/

  Limit alcohol and caffeine intake: Alcohol and caffeine can exacerbate IBD symptoms in some individuals. Watch your consumption and limit intake if you notice a connection between these substances and your symptoms. […] Stay up-to-date with vaccinations: People with IBD may be at a higher risk for infections. Talk to your doctor about recommended vaccinations and ensure you stay up-to-date with your immunizations. […] While these prevention tips can help manage IBD symptoms and reduce the risk of flare-ups, it is important to maintain regular communication with your gastroenterologist to address any concerns and track your condition closely. IBD management often requires a personalized approach based on your specific needs and symptoms.

• #56 Inflammatory Bowel Disease Treatment | Gastro MD

  https://gastro-md.com/specialties/intestine-colon-conditions/inflammatory-bowel-disease/

  Limit alcohol and caffeine intake: Alcohol and caffeine can exacerbate IBD symptoms in some individuals. Watch your consumption and limit intake if you notice a connection between these substances and your symptoms. […] Stay up-to-date with vaccinations: People with IBD may be at a higher risk for infections. Talk to your doctor about recommended vaccinations and ensure you stay up-to-date with your immunizations. […] While these prevention tips can help manage IBD symptoms and reduce the risk of flare-ups, it is important to maintain regular communication with your gastroenterologist to address any concerns and track your condition closely. IBD management often requires a personalized approach based on your specific needs and symptoms.

• #57 PREVENTION OF INFLAMMATORY BOWEL DISEASE COMPLICATIONS AND RECURRENCE | Revista Médica Clínica Las Condes

  https://www.elsevier.es/es-revista-revista-medica-clinica-las-condes-202-articulo-prevention-of-inflammatory-bowel-disease-S0716864019300732

  PREVENTION OF INFLAMMATORY BOWEL DISEASE COMPLICATIONS AND RECURRENCE […] This article describes the need for objective treatment and management goals of inflammatory bowel disease to monitor disease course and progression. We discuss the treat to target or tight control approach as an evolving treatment strategy in order to prevent future complications. […] The concept that targeted therapy with the use of objective markers will lead to better treatment outcomes is a relatively new paradigm in IBD. The so-called treat to target or tight control approach is becoming the standard of care in the treatment of many chronic conditions including IBD. […] Ultimately the management goal for patients with IBD should be to induce and maintain remission, which is defined by both patient-reported outcomes and objective markers.

• #58 PREVENTION OF INFLAMMATORY BOWEL DISEASE COMPLICATIONS AND RECURRENCE | Revista Médica Clínica Las Condes

  https://www.elsevier.es/es-revista-revista-medica-clinica-las-condes-202-articulo-prevention-of-inflammatory-bowel-disease-S0716864019300732

  PREVENTION OF INFLAMMATORY BOWEL DISEASE COMPLICATIONS AND RECURRENCE […] This article describes the need for objective treatment and management goals of inflammatory bowel disease to monitor disease course and progression. We discuss the treat to target or tight control approach as an evolving treatment strategy in order to prevent future complications. […] The concept that targeted therapy with the use of objective markers will lead to better treatment outcomes is a relatively new paradigm in IBD. The so-called treat to target or tight control approach is becoming the standard of care in the treatment of many chronic conditions including IBD. […] Ultimately the management goal for patients with IBD should be to induce and maintain remission, which is defined by both patient-reported outcomes and objective markers.

• #59 PREVENTION OF INFLAMMATORY BOWEL DISEASE COMPLICATIONS AND RECURRENCE | Revista Médica Clínica Las Condes

  https://www.elsevier.es/es-revista-revista-medica-clinica-las-condes-202-articulo-prevention-of-inflammatory-bowel-disease-S0716864019300732

  The strategy of treating to achieve specific targets has true benefits in multiple long-term critical outcomes. It is essential to employ strategies of continuous disease and drug monitoring to keep patients under optimal control. Emerging data demonstrate that this treat to target approach is both feasible and practical.

• #60 PREVENTION OF INFLAMMATORY BOWEL DISEASE COMPLICATIONS AND RECURRENCE | Revista Médica Clínica Las Condes

  https://www.elsevier.es/es-revista-revista-medica-clinica-las-condes-202-articulo-prevention-of-inflammatory-bowel-disease-S0716864019300732

  The strategy of treating to achieve specific targets has true benefits in multiple long-term critical outcomes. It is essential to employ strategies of continuous disease and drug monitoring to keep patients under optimal control. Emerging data demonstrate that this treat to target approach is both feasible and practical.

• #61 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro

  https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/

  Therefore, patients with longstanding colonic inflammation should undergo routine colonoscopy starting at 8-10 years of colonic disease duration, with subsequent colonoscopy intervals based on the results. […] Screening for depression and anxiety is recommended in all patients with IBD. […] Therefore, by intervening early and treating inflammation, with a goal of mucosal healing, we can potentially prevent these morbid and potentially life-threatening, complications of IBD. […] This proactive approach of addressing primary, secondary and tertiary prevention in IBD patients can ultimately help to reduce infectious, malignant and long-term disease-related complications.

• #62 Preventive health measures in inflammatory bowel disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/

  We aim to review the literature and provide guidance on preventive health measures in inflammatory bowel disease (IBD). […] Preventive health measures can avert morbidity and improve the quality of life of patients with IBD. Gastroenterologists and primary care physicians (PCPs) should have an up to date working knowledge of preventive health measures for IBD patients. A holistic approach and better communication between gastroenterologists and PCPs with explicit clarification of roles will prevent duplication of services and streamline care. […] Effective preventive measures to reduce morbidity, hospitalization, and surgery are critical to improving disease free remission and quality of life. […] Studies have shown that IBD patients do not receive preventive services with the same thoroughness as other medical patients.

• #63 Can You Prevent Inflammatory Bowel Disease? | Mass General Brigham

  https://www.massgeneralbrigham.org/en/about/newsroom/articles/prevent-inflammatory-bowel-disease

  In recognition of World Inflammatory Bowel Disease (IBD) Day, Ashwin Ananthakrishnan, MBBS, MPH, answers patients most commonly searched questions about IBD prevention and treatment. […] Dr. Ananthakrishnan and other investigators at Mass Generals Center for the Study of Inflammatory Bowel Disease conduct cutting-edge research to identify new treatments and ways to prevent IBD. […] Theres no known way to prevent IBD. But there may be things you can do to help reduce your risk. […] To help reduce your risk of developing IBD: Avoid processed food and additives. Eat a Mediterranean-style diet rich in fruits and vegetables. Get enough sleep. Limit exposure to antibiotics. Dont smoke. Reduce stress and anxiety. […] Breastfeeding during infancy has been shown to reduce risk of IBD in children. Studies also have shown that people who exercise regularly may have a lower risk of developing IBD.

• #64 Health Maintenance for Adult Patients with Inflammatory Bowel Disease

  https://pmc.ncbi.nlm.nih.gov/articles/PMC8608358/

  Patients with IBD who are receiving immunosuppression are at a 30% increased risk for cervical neoplasia compared to the general population. […] All patients with IBD, regardless of their disease subtype, should be encouraged to stop smoking due to the negative effect of tobacco smoking on their general well-being and the increased risk for many malignancies including lung and colon cancer. […] It is critical to screen patients with IBD for anxiety and depression especially since depressive severity was found to be a risk factor for suicidal ideation among these patients. […] Staying up-to-date with health care maintenance of patients with IBD is critical, especially given the increased risk for vaccine-preventable infections as well as comorbidities such as malignancies, bone, and mood disorders.

• #65 Targeting Disease Prediction and Prevention: the New Frontier in IBD

  https://reports.mountsinai.org/article/gi2023-04-targeting-ibd-prediction-and-prevention

  Mount Sinai researchers have found strong evidence that before the first symptoms of Crohns disease and ulcerative colitis occur, theres a preclinical phase in which immune and inflammatory pathways are already altered. By targeting and treating the early pathogenic events that promote IBD development, they believe, disease onset could be prevented or impeded. […] In other words, by targeting and treating the early pathogenic events that promote IBD development, disease onset could be prevented or impeded, and a true opportunity to change its course revealed. […] Being able to identify in the blood or stool those dysregulated pathways through biomarkers, such as proteomics, metabolomics, gut microbiome, and antimicrobial antibodies, will lead to the development of prediction models and prevention strategies. […] If were going to find a way to prevent Crohns disease and ulcerative colitis, it will require the global GI community actively embracing this new paradigm of prediction and prevention, declares Dr. Colombel.

• #66 GUILD Conference

  https://www.healio.com/news/gastroenterology/20220223/avoid-ibd-complications-with-3tiered-preventive-care-approach

  It is critical to consider all aspects of preventive care in patients with inflammatory bowel disease to avoid serious infections or complications, according to a presenter at GUILD 2022. […] Long noted there are three forms of preventive care in IBD: primary prevention, which includes immunizations; secondary prevention, including early-disease detection through screening programs; and tertiary prevention, which includes managing long-term disease and disability to prevent further complications. […] Each of these forms of prevention needs to be addressed with our inflammatory bowel disease patients, Long said. […] Because patients with IBD are at an increased risk for both serious and opportunistic infections, we can address preventive aspects to try to prevent this, Long said. […] Please remember primary, secondary and tertiary prevention at the time of IBD diagnosis, Long said. Really think about things like initiating a medication for IBD to prevent downstream complications, that’s tertiary. Think about sunscreen, use vaccines, that’s primary; and then do appropriate secondary prevention screenings for your individual patient.

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