Materiały źródłowe

• #1 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://www.jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  Pagets disease of the breast is named after the 19th-century British doctor Sir James Paget, who, in 1874, noted a distinct connection relationship between cancer of the breast and the nipple. It is considered one of the rare forms of breast cancer and is often misdiagnosed when first noted. Typically noted in older, postmenopausal women, it comprises approximately 5% of all breast cancer cases diagnosed. The eczematous presentation of Pagets disease of the nipple is the most misleading feature of this disease. Such patients are usually mistakenly treated by the primary care physician for eczema. The initial skin changes of Pagets disease of the breast may appear relatively benign, and many individuals may overlook such symptoms, mistakenly attributing them to an inflammatory skin condition or infection. As a result, diagnosis may be delayed, often up to 6 months or more. Most individuals with the condition eventually seek medical attention, but generally only after other topical modalities have been used. This may lead to progression of disease, eventually resulting into an associated lump with enlarged axillary lymph nodes.

• #2 Paget’s Disease of the Breast: Symptoms, Causes, Diagnosis, Treatment, and Prevention

  https://www.everydayhealth.com/breast-cancer/guide/paget-disease/

  Pagets disease of the breast also known as Pagets disease of the nipple, mammary Pagets disease, or sometimes Pagets nipple disease is a rare form of breast cancer that affects the skin of the nipple and usually the surrounding areola (the darker circle of skin around the nipple). Its usually only found in one breast. […] Pagets disease occurs in about 1 to 3 percent of breast cancer cases, and is almost always found in the presence of other tumors in the same breast, including ductal carcinoma in situ (DCIS) or infiltrating ductal carcinoma (IDC). […] The symptoms of Pagets disease appear on the nipple and usually the areola. Most often, they occur on one breast, but they can also occur on both breasts. These symptoms include: Itching or burning on the nipple, Crusting or oozing skin on the nipple or areola, Flaky or scaly skin on the nipple, Newly flattened or turned-in (inverted) nipple, A rash that can appear discolored, raised, or raw on the nipple area, Yellow or bloody nipple discharge.

• #3 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  Pagets disease of the breast is named after the 19th-century British doctor Sir James Paget, who, in 1874, noted a distinct connection relationship between cancer of the breast and the nipple. It is considered one of the rare forms of breast cancer and is often misdiagnosed when first noted. Typically noted in older, postmenopausal women, it comprises approximately 5% of all breast cancer cases diagnosed. The eczematous presentation of Pagets disease of the nipple is the most misleading feature of this disease. Such patients are usually mistakenly treated by the primary care physician for eczema. The initial skin changes of Pagets disease of the breast may appear relatively benign, and many individuals may overlook such symptoms, mistakenly attributing them to an inflammatory skin condition or infection. As a result, diagnosis may be delayed, often up to 6 months or more. Most individuals with the condition eventually seek medical attention, but generally only after other topical modalities have been used. This may lead to progression of disease, eventually resulting into an associated lump with enlarged axillary lymph nodes.

• #4

  https://www.nursingcenter.com/journalarticle?Article_ID=5555113&Journal_ID=849729&Issue_ID=5555089

  ABSTRACT: Paget’s disease of the breast (PDB) is a rare disorder of the nipple-areola complex that may present clinically as a unilateral, eczematous, or ulcerated papule or plaque. This case highlights the importance of either punch or incisional wedge biopsy to establish a diagnosis of PDB for patients who present with chronic cutaneous changes of the nipple, areola, or skin of the breast, regardless of any previous normal mammogram or breast ultrasound. Mammography alone cannot rule out a diagnosis of PDB in a patient with cutaneous changes of the breast. […] PDB is characterized histologically by Paget cells in the nipple epidermis, which are thought to migrate there from breast carcinoma present in deeper ductal structures. […] Treatment and prognosis of PDB depend on the type of underlying associated breast carcinoma and presence or absence of axillary lymph node involvement. Treatment of PDB is typically composed of surgery, chemotherapy, or radiation therapy, either alone or in combination. Patients with PDB should be promptly referred to oncology for staging and treatment.

• #5

  https://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=uh4323

  Paget disease of the breast is a type of cancer. Breast cancer is the abnormal growth of cells in the breast. In Paget disease of the breast, some people notice a change in the skin of their nipple and the area around the nipple (areola). The skin can be reddish and scaly. Other people don’t notice any skin changes but do have pain, burning, or itching on their nipple. […] Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor or nurse advice line (811 in most provinces and territories) if you are having problems. It’s also a good idea to know your test results and keep a list of the medicines you take. […] There are things you can do at home to help manage the symptoms of cancer and the side effects of treatment. Your doctor may also give you medicines to help with certain side effects.

• #6 Paget’s disease of the breast: Causes, symptoms, treatment, and more

  https://www.medicalnewstoday.com/articles/192362

  Pagets disease of the breast may resemble other common skin issues, such as wounds, breastfeeding-related injuries, or eczema. […] Pagets disease of the breast is a rare type of breast cancer. […] This disease can affect anyone, but it occurs more commonly in postmenopausal females in their 50s. […] According to the National Health Service in the United Kingdom, about 1% to 4% of females with breast cancer have Pagets disease of the breast. […] The symptoms of Pagets disease vary depending on the stage of development. […] According to the American Cancer Society, Pagets disease usually appears in one breast or nipple. The most common symptoms include: itching, tingling, or burning around the nipple and areola; skin discoloration; flaking, thickening, or scaling of the skin around the nipple that does not heal over time; nipple discharge, which may be yellow or contain blood; flattened or inverted nipples; a crusted lesion with irregular edges; a mass in the nipple; ulceration, in some cases.

• #7 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://www.jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  Symptoms of Pagets disease of the breast can be very similar to benign skin conditions and can include any of the following: Itching or tingling of the nipple or areola, Redness, Flaking, crusty, or thickened skin on or around the nipple, A flattened nipple, Discharge from the nipple that may be yellowish or bloody, A lump in the breast. It is not uncommon for there to be multiple symptoms with varying degrees of resolution with topical treatment. […] Because these underlying malignancies tend to be multifocal and multicentric, mammography often is not sufficient, and an MRI may be necessary to evaluate the true extent of the disease. Treatment of this form of breast cancer is typically multifactorial in that clear margins versus final cosmesis must be considered. As this is generally located in the central part of the breast, it may be difficult to preserve the nipple areolar complex, and simple mastectomy with sentinel lymph node dissection is often the best approach. It has been noted in recent literature that both total mastectomy and breast-preserving surgery followed by appropriate adjuvant therapy are acceptable treatment options for carefully selected patients with Pagets disease.

• #8 Paget’s Disease of the Breast: Symptoms, Causes, Diagnosis, Treatment, and Prevention

  https://www.everydayhealth.com/breast-cancer/guide/paget-disease/

  Pagets disease of the breast also known as Pagets disease of the nipple, mammary Pagets disease, or sometimes Pagets nipple disease is a rare form of breast cancer that affects the skin of the nipple and usually the surrounding areola (the darker circle of skin around the nipple). Its usually only found in one breast. […] Pagets disease occurs in about 1 to 3 percent of breast cancer cases, and is almost always found in the presence of other tumors in the same breast, including ductal carcinoma in situ (DCIS) or infiltrating ductal carcinoma (IDC). […] The symptoms of Pagets disease appear on the nipple and usually the areola. Most often, they occur on one breast, but they can also occur on both breasts. These symptoms include: Itching or burning on the nipple, Crusting or oozing skin on the nipple or areola, Flaky or scaly skin on the nipple, Newly flattened or turned-in (inverted) nipple, A rash that can appear discolored, raised, or raw on the nipple area, Yellow or bloody nipple discharge.

• #9 Nipples – Physician Guide to Breastfeeding

  https://physicianguidetobreastfeeding.org/maternal-concerns/nipples/

  Pagets disease presents most commonly in older postmenopausal women and comprises 0.5-5% of all breast cancer. While it is important to refer any woman with a concerning finding to a breast surgeon for evaluation, this disease is extremely uncommon in younger lactating women. Pagetoid changes must start with the nipple and spread outward toward the areola over the course of many years. In contrast, dermatitis (allergy or eczema), occurs very frequently in breastfeeding women and starts on the areola or breast skin. Dermatitis rarely involves the nipple. […] Chronic Pagetoid changes with destruction of nipple. Chronic Pagetoid changes with near complete erosion of the nipple and areola. Patient had a previous history of breast reduction with Wise pattern closure incisions visible. Paget’s disease right nipple Patient with history of right breast cancer treated with a nipple sparing mastectomy who presented with new nipple changes and biopsy showed Pagetoid cells and recurrence of her cancer. Normal nipple of left breast is shown in comparison in photo to right. Paget’s disease right nipple Paget’s Left nipple Paget’s disease after about one year of progressive changes with redness and morphology.

• #10 What Is Paget’s Disease of the Breast | Breast Care Center Miami

  https://www.toplinemd.com/breast-care-center-of-miami/blog/what-is-pagets-disease-of-the-breast/

  Paget’s disease of the nipple is often mistaken for eczema or dermatitis due to its skin-related symptoms. However, unlike these conditions, Paget’s disease is linked to an underlying breast cancer. Early detection and treatment are crucial, as the condition can progress to more advanced stages if left untreated. […] Given that Paget’s disease of the nipple often mimics skin conditions like eczema, distinguishing between them is critical for timely treatment. Unlike eczema, Paget’s disease typically affects only one nipple and does not respond to topical steroids or other eczema treatments. If a persistent skin condition on the nipple does not improve with standard treatments, a biopsy should be considered to rule out Paget’s disease. […] Regular breast examinations, both self-exams and clinical exams, are vital for early detection of Paget’s disease of breast symptoms. Women should familiarize themselves with their breasts’ normal look and feel and report any changes, such as nipple discharge or scaling, to their healthcare provider promptly. Mammograms should also be a regular part of a woman’s healthcare regimen, especially if they are in a higher-risk category.

• #11 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  Pagets disease of the breast is named after the 19th-century British doctor Sir James Paget, who, in 1874, noted a distinct connection relationship between cancer of the breast and the nipple. It is considered one of the rare forms of breast cancer and is often misdiagnosed when first noted. Typically noted in older, postmenopausal women, it comprises approximately 5% of all breast cancer cases diagnosed. The eczematous presentation of Pagets disease of the nipple is the most misleading feature of this disease. Such patients are usually mistakenly treated by the primary care physician for eczema. The initial skin changes of Pagets disease of the breast may appear relatively benign, and many individuals may overlook such symptoms, mistakenly attributing them to an inflammatory skin condition or infection. As a result, diagnosis may be delayed, often up to 6 months or more. Most individuals with the condition eventually seek medical attention, but generally only after other topical modalities have been used. This may lead to progression of disease, eventually resulting into an associated lump with enlarged axillary lymph nodes.

• #12 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Pagets-Disease-of-the-Nipple.aspx

  Paget’s disease of the nipple (or mammary Paget disease) is an uncommon form of breast cancer characterized by the accumulation of cancer cells in or surrounding the nipple. It occurs in less than 5% of diagnosed breast cancer patients and is most common in women after the age of 50. Despite this, occurrence in adolescents and in the elderly is not unheard of. […] Paget’s disease usually begins in the milk-carrying ducts of the nipple before spreading to the exterior surface of the nipple and the areola, which become flaky, reddened, and irritated. In most cases, the disease affects only one breast, not both. […] Paget’s disease of the nipple is rare; therefore it is very commonly misdiagnosed as skin conditions including eczema. In fact, it may take several months to receive a correct diagnosis. The fact that over 97% of those with the disease also suffer from cancer elsewhere in the breast highlights the need for symptom awareness.

• #13

  https://www.nhs.uk/conditions/pagets-disease-nipple/

  Paget’s disease of the nipple, also known as Paget’s disease of the breast, is a rare condition associated with breast cancer. […] Paget’s disease of the nipple always starts in the nipple and may extend to the areola. It appears as a red, scaly rash on the skin of the nipple and areola. […] A biopsy is used to confirm a suspected diagnosis of Paget’s disease of the nipple. A small tissue sample (punch biopsy of the skin) will be taken from your nipple and examined under a microscope to see if it’s cancerous. […] Surgery is the main treatment for Paget’s disease of the nipple. Depending on whether the cancer has spread, surgery will either involve removing the whole breast (a mastectomy), or the nipple and areola with the breast tissue underneath them (a central excision). […] If Paget’s disease is detected and treated in its early stages, there’s a good chance of a full recovery.

• #14 Paget’s Disease of the Nipple | Breast Cancer Trials

  https://www.breastcancertrials.org.au/pagets-disease-of-the-nipple/?srsltid=AfmBOor-zDeuTCaHVlXhD1y77ywK9Y1G5mVSlr6HUdh2Dbm6VlxChuyR

  Pagets disease of the nipple, also known as Pagets disease of the breast, is a rare form of breast cancer that affects the nipple and the area around the nipple (the areola). […] The main sign of Pagets disease of the nipple is a change in the nipple and/or areola. […] Symptoms of Pagets disease of the nipple may include: Itching, tingling or redness in the nipple and/or areola, Flaking crusting or thickened skin on or around the nipple, A flattened nipple, Yellowish or bloody discharge from the nipple. […] If you notice any changes in the skin of your nipple or areola, you should consult your GP or doctor. […] A nipple biopsy will be used to correctly diagnose Pagets disease of the nipple. […] Treatment for Pagets disease of the nipple will depend on how much of the nipple, areola and breast is affected.

• #15 Paget’s Disease of the Breast: Symptoms, Treatment, and More

  https://www.healthline.com/health/breast-cancer/pagets-disease-of-the-breast

  Pagets disease of the breast, or of the nipple, is a rare form of breast cancer. The symptoms are different from other breast cancer types, and the condition affects the surface skin of the nipple and areola. […] If you have any of these signs and symptoms, see your doctor as soon as possible. […] Diagnosis begins with a physical examination. Your doctor will observe the appearance of your breasts, especially around the nipples, and check for lumps or unusual thickening. […] The only way to confirm breast cancer is with a biopsy. This is a procedure in which a needle is used to obtain a small sample of breast tissue from a nipple, areola, or tumor. […] Your oncologist will come up with a treatment plan that takes many factors into account, such as the size and grade of the breast tumor, if any, and if the cancer has spread (stage).

• #16

  https://www.nursingcenter.com/journalarticle?Article_ID=5555113&Journal_ID=849729&Issue_ID=5555089

  A full-thickness surgical punch or wedge biopsy is the gold standard to confirm or exclude a diagnosis of PDB. It is especially important to remember that patients who present with PDB isolated to the nipple and without a palpable breast mass may present with a normal mammogram despite presence of underlying IDC or ductal carcinoma in situ. Mammography has low sensitivity to detect PDB and should be used as a complimentary diagnostic tool to surgical wedge or punch biopsy when PDB is suspected.

• #17

  https://www.nursingcenter.com/journalarticle?Article_ID=5555113&Journal_ID=849729&Issue_ID=5555089

  A full-thickness surgical punch or wedge biopsy is the gold standard to confirm or exclude a diagnosis of PDB. It is especially important to remember that patients who present with PDB isolated to the nipple and without a palpable breast mass may present with a normal mammogram despite presence of underlying IDC or ductal carcinoma in situ. Mammography has low sensitivity to detect PDB and should be used as a complimentary diagnostic tool to surgical wedge or punch biopsy when PDB is suspected.

• #18 Paget Disease of the Breast in Pregnancy and Lactation – PubMed

  https://pubmed.ncbi.nlm.nih.gov/32816273/

  Paget’s disease of the breast (PDB) is a rare breast carcinoma believed to arise from an underlying in situ or invasive ductal cancer that migrates through the epidermis causing characteristic skin changes including scaling, redness, and itching of the nipple, areola, and sometimes the surrounding skin. […] The workup of Paget’s should focus on both making the diagnosis with nipple/skin scrape cytology or punch biopsy as well as evaluating any underlying mass with mammogram, breast ultrasound, and also a core needle biopsy, if required. […] Treatment focuses on management of the underlying breast cancer as usual. […] The purpose of this chapter is to describe the presentation of PDB as well as outline an approach to its diagnosis and management, especially in the setting of pregnancy and lactation.

• #19 Paget’s disease of the breast | Breast Cancer Now

  https://breastcancernow.org/about-breast-cancer/diagnosis/types-of-breast-cancer/pagets-disease-of-the-breast

  Pagets disease of the breast is an uncommon type of breast cancer. […] Its sometimes called Pagets disease of the nipple. […] Treatment aims to remove the area of Pagets disease from your breast and reduce the risk of it coming back or spreading to other parts of the body. […] Surgery is usually the first treatment for Pagets disease of the breast. […] If youve been diagnosed with Pagets disease alone, youre most likely to be offered surgery to remove your nipple and areola. […] You may also need to have surgery to your lymph nodes. […] Depending on the features of your Pagets disease, you may also be offered radiotherapy after your surgery. […] If you have invasive breast cancer in addition to Pagets disease, you may be given some treatments before surgery. […] You’ll usually continue to be monitored for 5 years after your hospital-based treatments (such as surgery or radiotherapy) finish. […] It’s important to be aware of any changes to your breast, chest or surrounding area. […] Most breast cancers dont come back after treatment. But sometimes it can return, so its important you know what signs and symptoms to look out for.

• #20

  https://www.nhs.uk/conditions/pagets-disease-nipple/treatment/

  Paget’s disease of the nipple is usually associated with breast cancer. […] If you’re diagnosed with Paget’s disease of the nipple, surgery is often the first type of treatment you’ll receive. […] If you have Paget’s disease of the nipple, your nipple areola will also be removed. […] After having breast-conserving surgery, it’s likely you’ll need to have radiotherapy to destroy any remaining cancer cells. […] If you have a mastectomy, you may be able to have reconstructive surgery to recreate your breast. […] If you decide not to have breast reconstruction, you can wear a false breast or breast prosthesis, which is available free on the NHS. […] After your surgery, you may need further treatment if you have invasive breast cancer (where the cancerous cells have spread into other tissue in your breast).

• #21 Paget’s Disease of the Nipple | Magee-Women’s Hospital

  https://www.upmc.com/locations/hospitals/magee/services/magee-womens-cancers/breast-cancer-program/types-of-breast-cancer/pagets-disease

  Pagets disease of the nipple is a rare type of breast cancer affecting the nipple and the areola (the circle of skin surrounding the nipple). […] Doctors treat Paget’s disease of the nipple with surgery and radiation. […] The goal of treatment for Pagets disease is to remove as much of the cancer as possible and to prevent cancer cells from spreading. […] Doctors treat Pagets disease with surgery. They may also recommend other cancer treatments, like radiation. […] Surgery is almost always used to treat Pagets disease. Your doctor may recommend breast-conserving surgery, where they remove your nipple and areola but preserve the rest of your breast. […] Doctors often treat Paget’s disease with radiation therapy, which uses high-energy rays to destroy cancer cells. Radiation therapy reduces the odds that cancer will come back.

• #22 Paget’s disease of the nipple | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/cancer/cancer-types-in-adults/pagets-disease-of-the-nipple/

  Pagets disease is treated in the same way as breast cancer. […] Surgery is usually the first line of treatment but unlike other forms of breast cancer, it involves removing breast tissue that includes the nipple and areola. […] If Pagets disease is detected and treated in its early stages, theres a good chance of recovery. […] Pagets disease of the nipple is often associated with other forms of breast cancer. […] Its usually treated in the same way as more common types of breast cancer, either by removing the cancerous section of the breast or sometimes by removing the entire breast a procedure known as a mastectomy. […] If youre diagnosed with Pagets disease, surgery is often the first form of treatment you will receive. […] These types of surgery will also involve removing your nipple and the darker area of skin surrounding it (the areola).

• #23 Treatment options for Paget’s disease of the nipple | Cancer Australia

  https://www.canceraustralia.gov.au/cancer-types/breast-cancer/treatment-options/treatment-options-pagets-disease-nipple

  Everyone is different, and the treatments recommended for Paget’s disease of the nipple may vary according to individual circumstances. […] Treatment for Paget’s disease of the nipple will depend on how much of the nipple, areola and breast is involved. […] Where Paget’s disease of the nipple is the only cancer in the breast, treatment usually involves: breast surgery and/or radiotherapy. […] Surgery for Paget’s disease of the nipple usually involves removal the nipple and some surrounding tissue. […] If the nipple is the only area of the breast affected, it’s possible that only the nipple and an area of healthy tissue around it will be removed. This is known as breast conserving surgery. […] Removal of the whole breast (mastectomy) and/or removal of one or more lymph nodes from the armpit may be needed for some patients.

• #24 Paget’s disease of the breast | Breast cancer | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/breast-cancer/types/pagets-disease-breast

  Paget’s disease of the breast is a rare condition of the nipple that is associated with some breast cancers. […] Pagets disease is a sign that there might be breast cancer in the tissues behind the nipple. […] About half of the people diagnosed with Paget’s disease of the breast have a lump behind the nipple. […] But most people with Pagets disease of the breast who have no lump behind the nipple, have ductal carcinoma in situ (DCIS). […] The main treatment is surgery. You have surgery to remove just the affected area (breast conserving surgery) or the whole breast (mastectomy). […] For some women, it is possible to remove just the affected area together with a border of healthy tissue. […] Your surgeon may recommend you have a mastectomy if the Paget’s disease affects a large area.

• #25

  https://www.nhs.uk/conditions/pagets-disease-nipple/treatment/

  Paget’s disease of the nipple is usually associated with breast cancer. […] If you’re diagnosed with Paget’s disease of the nipple, surgery is often the first type of treatment you’ll receive. […] If you have Paget’s disease of the nipple, your nipple areola will also be removed. […] After having breast-conserving surgery, it’s likely you’ll need to have radiotherapy to destroy any remaining cancer cells. […] If you have a mastectomy, you may be able to have reconstructive surgery to recreate your breast. […] If you decide not to have breast reconstruction, you can wear a false breast or breast prosthesis, which is available free on the NHS. […] After your surgery, you may need further treatment if you have invasive breast cancer (where the cancerous cells have spread into other tissue in your breast).

• #26 Paget’s disease of the nipple | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/cancer/cancer-types-in-adults/pagets-disease-of-the-nipple/

  Pagets disease is treated in the same way as breast cancer. […] Surgery is usually the first line of treatment but unlike other forms of breast cancer, it involves removing breast tissue that includes the nipple and areola. […] If Pagets disease is detected and treated in its early stages, theres a good chance of recovery. […] Pagets disease of the nipple is often associated with other forms of breast cancer. […] Its usually treated in the same way as more common types of breast cancer, either by removing the cancerous section of the breast or sometimes by removing the entire breast a procedure known as a mastectomy. […] If youre diagnosed with Pagets disease, surgery is often the first form of treatment you will receive. […] These types of surgery will also involve removing your nipple and the darker area of skin surrounding it (the areola).

• #27 Paget’s Disease of the Nipple | Cancer Care & Oncology | Bon Secours

  https://www.bonsecours.com/health-care-services/cancer-care-oncology/conditions/pagets-disease-of-the-nipple

  Pagets disease of the nipple is a rare breast cancer that begins in the nipple and spreads to the areola. […] Treatment for Pagets disease of the nipple typically includes surgery, followed by other therapies such as chemotherapy, radiation therapy or hormone therapy. […] Depending on your personal health history, the extent of your Pagets disease of the nipple and other factors, your oncologist may recommend one or more of the following treatment options: […] Surgery – if you are diagnosed with Pagets disease of the nipple, you will likely need to undergo surgery. […] Chemotherapy – you may need to undergo chemotherapy after your surgical treatment. […] Hormone therapy – your doctor may prescribe hormone medications, which can reduce your chance of recurrence of Pagets disease of the nipple after you have undergone surgery to remove the affected area. […] Radiation therapy – you may need to undergo radiation therapy after your surgery for Pagets disease of the nipple.

• #28 Paget’s disease of the nipple | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/cancer/cancer-types-in-adults/pagets-disease-of-the-nipple/

  After having breast-conserving surgery, its likely you will need radiation treatment (radiotherapy) to destroy any remaining cancer cells. […] If you have Pagets disease, your nipple and areola will be removed. You should be offered reconstructive surgery to improve the appearance of your breast after surgery. […] After your surgery, you may need further treatment if you have invasive breast cancer, where the cancerous cells have spread into other tissue in your breast. […] Other types of treatment for breast cancer include: chemotherapy cytotoxic medication that prevents cancer cells from dividing and growing is used to destroy cancer cells, radiotherapy where controlled doses of high-energy radiation, usually X-rays, are used to destroy cancer cells, biological therapy if your breast cancer is HER2 positive, biological therapy, usually a medication called trastuzumab, can be used to treat the cancer by stopping the effects of HER2 and helping your immune system fight off cancer cells, hormone therapy if your breast cancer is hormone-receptor positive, hormone therapy can be used to treat the cancer by lowering the levels of hormones in your body or stopping their effects.

• #29

  https://www.advocatehealth.com/health-services/cancer-institute/cancers-we-treat/breast-cancer/pagets-disease-breast

  Paget’s disease of the breast, often referred to as Pagets disease of the nipple, is a rare type of breast cancer that affects the skin on your nipple. […] Early detection and treatment are crucial for managing this disease effectively. […] Paget’s disease of the breast requires prompt medical attention. […] Regular self-exams and monitoring for any changes in the skin of your nipple and areola can aid in early detection, improving the chances of successful treatment. […] The main treatment options include: Surgery, Radiation therapy, Chemotherapy, Hormone therapy, Targeted therapy. […] Your care team at Advocate Health Care will use a collaborative approach to provide the best treatment possible. We also offer supportive care services such as counseling, nutrition therapy, palliative care and physical therapy that may be beneficial to help you manage the physical and emotional challenges of cancer treatment.

• #30 Paget’s disease of the breast | Breast Cancer Now

  https://breastcancernow.org/about-breast-cancer/diagnosis/types-of-breast-cancer/pagets-disease-of-the-breast

  Pagets disease of the breast is an uncommon type of breast cancer. […] Its sometimes called Pagets disease of the nipple. […] Treatment aims to remove the area of Pagets disease from your breast and reduce the risk of it coming back or spreading to other parts of the body. […] Surgery is usually the first treatment for Pagets disease of the breast. […] If youve been diagnosed with Pagets disease alone, youre most likely to be offered surgery to remove your nipple and areola. […] You may also need to have surgery to your lymph nodes. […] Depending on the features of your Pagets disease, you may also be offered radiotherapy after your surgery. […] If you have invasive breast cancer in addition to Pagets disease, you may be given some treatments before surgery. […] You’ll usually continue to be monitored for 5 years after your hospital-based treatments (such as surgery or radiotherapy) finish. […] It’s important to be aware of any changes to your breast, chest or surrounding area. […] Most breast cancers dont come back after treatment. But sometimes it can return, so its important you know what signs and symptoms to look out for.

• #31 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  Treatment of this form of breast cancer is typically multifactorial in that clear margins versus final cosmesis must be considered. As this is generally located in the central part of the breast, it may be difficult to preserve the nipple areolar complex, and simple mastectomy with sentinel lymph node dissection is often the best approach. It has been noted in recent literature that both total mastectomy and breast-preserving surgery followed by appropriate adjuvant therapy are acceptable treatment options for carefully selected patients with Pagets disease. […] After surgery, radiation therapy and perhaps chemotherapy, targeted therapy, and/or hormone therapy may be recommended. About 97% of people diagnosed with Pagets disease of the nipple also have ductal carcinoma in situ or invasive cancer somewhere else in the breast. The exact treatment plan will depend on the characteristics of the underlying breast cancer such as stage, grade, and whether the cancer is hormone receptor-positive and/or HER2-positive. As in other breast cancer diagnoses and treatment, a consultation with a medical oncologist would be prudent.

• #32 logo–sylvester

  https://umiamihealth.org/en/sylvester-comprehensive-cancer-center/treatments-and-services/breast-cancer/paget%E2%80%99s-disease-of-the-nipple-

  If you have an invasive cancer in addition to Paget’s disease, your doctor may recommend removing your entire breast, called a mastectomy, to make sure all cancer cells are removed. […] If Paget’s disease is confined to your nipple and areola and no cancer cells were found in your lymph nodes, you won’t need any additional treatment after radiation therapy. […] Since most people with Paget’s disease of the nipple also have invasive breast cancer, your treatment will be based on the type and stage of cancer you have.

• #33

  https://www.aurorahealthcare.org/services/cancer/breast-cancer/pagets-disease-breast

  Treating Paget’s disease of the breast typically involves addressing both the disease in the nipple area and any underlying breast cancer. The most common treatment for Pagets disease of the breast is surgery. […] Your care team at Aurora Health Care will use a collaborative approach to provide the best treatment possible. Supportive care services such as counseling, nutrition therapy, palliative care and physical therapy may also be offered to help you manage the physical and emotional challenges of cancer treatment.

• #34 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  The nurse navigator was an essential part of her cancer care team and was available for support, resources, and information. With the assistance of the navigator, the patient was prepared for surgery, referred to a support group, and given information on financial assistance. […] Patients with Pagets disease are no different. However, there are times when a patient may first be shaken by a diagnosis of cancer that might have been primarily treated as a dermatologic issue. After an introduction, the navigator should begin to establish a relationship of trust and empathy. This early introduction will allow for the coordination of care with the multidisciplinary team and give the patient confidence that the navigator will act as her advocate in all areas of treatment, which could lead to improved adherence to the care suggested.

• #35 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  The nurse navigator was an essential part of her cancer care team and was available for support, resources, and information. With the assistance of the navigator, the patient was prepared for surgery, referred to a support group, and given information on financial assistance. […] Patients with Pagets disease are no different. However, there are times when a patient may first be shaken by a diagnosis of cancer that might have been primarily treated as a dermatologic issue. After an introduction, the navigator should begin to establish a relationship of trust and empathy. This early introduction will allow for the coordination of care with the multidisciplinary team and give the patient confidence that the navigator will act as her advocate in all areas of treatment, which could lead to improved adherence to the care suggested.

• #36 What Is Paget’s Disease of the Breast | Breast Care Center Miami

  https://www.toplinemd.com/breast-care-center-of-miami/blog/what-is-pagets-disease-of-the-breast/

  The diagnosis of Paget’s disease can have a significant psychological impact on patients. Dealing with the diagnosis, treatment, and physical changes to the breast or nipple can be emotionally challenging. It’s important for patients to have access to psychological support, such as counseling or support groups, where they can share their experiences and feelings. Emotional and psychological support is as crucial as the physical treatment of the disease.

• #37 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  The nurse navigator was an essential part of her cancer care team and was available for support, resources, and information. With the assistance of the navigator, the patient was prepared for surgery, referred to a support group, and given information on financial assistance. […] Patients with Pagets disease are no different. However, there are times when a patient may first be shaken by a diagnosis of cancer that might have been primarily treated as a dermatologic issue. After an introduction, the navigator should begin to establish a relationship of trust and empathy. This early introduction will allow for the coordination of care with the multidisciplinary team and give the patient confidence that the navigator will act as her advocate in all areas of treatment, which could lead to improved adherence to the care suggested.

• #38 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://www.jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  After surgery, radiation therapy and perhaps chemotherapy, targeted therapy, and/or hormone therapy may be recommended. About 97% of people diagnosed with Pagets disease of the nipple also have ductal carcinoma in situ or invasive cancer somewhere else in the breast. The exact treatment plan will depend on the characteristics of the underlying breast cancer such as stage, grade, and whether the cancer is hormone receptor-positive and/or HER2-positive. As in other breast cancer diagnoses and treatment, a consultation with a medical oncologist would be prudent. […] As with any breast cancer patient, the navigator plays an important role in the support and coordination of care. Patients with Pagets disease are no different. However, there are times when a patient may first be shaken by a diagnosis of cancer that might have been primarily treated as a dermatologic issue. After an introduction, the navigator should begin to establish a relationship of trust and empathy. This early introduction will allow for the coordination of care with the multidisciplinary team and give the patient confidence that the navigator will act as her advocate in all areas of treatment, which could lead to improved adherence to the care suggested.

• #39 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://www.jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  After surgery, radiation therapy and perhaps chemotherapy, targeted therapy, and/or hormone therapy may be recommended. About 97% of people diagnosed with Pagets disease of the nipple also have ductal carcinoma in situ or invasive cancer somewhere else in the breast. The exact treatment plan will depend on the characteristics of the underlying breast cancer such as stage, grade, and whether the cancer is hormone receptor-positive and/or HER2-positive. As in other breast cancer diagnoses and treatment, a consultation with a medical oncologist would be prudent. […] As with any breast cancer patient, the navigator plays an important role in the support and coordination of care. Patients with Pagets disease are no different. However, there are times when a patient may first be shaken by a diagnosis of cancer that might have been primarily treated as a dermatologic issue. After an introduction, the navigator should begin to establish a relationship of trust and empathy. This early introduction will allow for the coordination of care with the multidisciplinary team and give the patient confidence that the navigator will act as her advocate in all areas of treatment, which could lead to improved adherence to the care suggested.

• #40 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://www.jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  There is abundant literature about the navigation role and the positive impact it can have on patient outcomes and continuity of care. Despite the rarity of Pagets disease of the breast, the breast care navigators can validate their essential role as partner and advocate for patients at the most vulnerable of times.

• #41 Paget Disease of the Breast: Care Instructions | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.paget-disease-of-the-breast-care-instructions.uh4323

  Paget disease of the breast is a type of cancer. Breast cancer is the abnormal growth of cells in the breast. In Paget disease of the breast, some people notice a change in the skin of their nipple and the area around the nipple (areola). The skin can be reddish and scaly. Other people don’t notice any skin changes but do have pain, burning, or itching on their nipple. […] Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It’s also a good idea to know your test results and keep a list of the medicines you take. […] There are things you can do at home to help manage the symptoms of cancer and the side effects of treatment. Your doctor may also give you medicines to help with certain side effects. […] Watch closely for changes in your health, and be sure to contact your doctor if you have any symptoms that the cancer has come back or spread. These symptoms include: New lumps. Bone pain. Chest pain. Shortness of breath. Belly pain. Headaches that don’t go away.

• #42 Treatment options for Paget’s disease of the nipple | Cancer Australia

  https://www.canceraustralia.gov.au/cancer-types/breast-cancer/treatment-options/treatment-options-pagets-disease-nipple

  For women with Paget’s disease of the nipple, radiotherapy is almost always recommended after breast conserving surgery. […] Radiotherapy is sometimes recommended after mastectomy. […] For some women with Paget’s disease of the nipple, radiotherapy may be the only treatment needed after the biopsy used during diagnosis. […] Once treatment is finished, regular follow-up appointments with your specialist or general practitioner are recommended. […] Follow-up after treatment for Paget’s disease of the nipple usually involves a regular physical examination and an annual mammogram with or without an ultrasound. […] Breast care nurses specialise in caring for women with breast cancer and can be a valuable source of information and support.

• #43

  https://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=uh4323

  Call your doctor or nurse advice line now or seek immediate medical care if: You have a fever or chills. Or you may be sweating. You have abnormal bleeding. You have new or worse pain. You think you have an infection. You have new symptoms, such as a cough, belly pain, vomiting, diarrhea, or a rash. You have signs of a blood clot, such as: Pain in your calf, back of the knee, thigh, or groin. Redness and swelling in your leg or groin. […] Watch closely for changes in your health, and be sure to contact your doctor or nurse advice line if you have any symptoms that the cancer has come back or spread. These symptoms include: New lumps. Bone pain. Chest pain. Shortness of breath. Belly pain. Headaches that don’t go away.

• #44 Paget’s disease of the breast | Breast cancer | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/breast-cancer/types/pagets-disease-breast

  You might have more treatment after surgery if you have Pagets disease with invasive breast cancer or DCIS. […] You usually have regular check ups after treatment for Pagets disease of the breast. […] Its important to remember that you can contact your doctor or specialist nurse if you notice a new symptom or have questions between your check ups. […] Coping with breast cancer can be difficult. There is help and support available to you and your family.

• #45 Paget’s Disease of the Breast: Symptoms, Treatment, and More

  https://www.healthline.com/health/breast-cancer/pagets-disease-of-the-breast

  Surgery might be followed by radiation therapy to target any cancer cells that were missed. […] One potential complication of this type of breast cancer is that symptoms can be easily dismissed or misdiagnosed, delaying treatment. […] Breast cancer treatment can increase your long-term risk of a variety of conditions, such as lymphedema, due to removal of lymph nodes.

• #46 Paget’s — Cancer Survivors Network

  https://csn.cancer.org/discussion/142683/pagets

  Yes, Paget’s Disease is a rare form of breast cancer. It consists of only 1% of all breast cancers. It usually occurs in older women (50-60 range) Paget’s is breast cancer of the nipple, usually also involving the milk ducts underneath. I just saw the oncologist and my case involved DCIS as well as Paget’s. I am looking for other women who wanted to continue breastfeeding. Most of the doctors I’ve seen have not seen someone in this situation. I guess it is very rare to be diagnosed while breastfeeding. Most told me I needed to stop, but could not offer a good reason why. Are there other women who were told the same thing? Thanks! […] I was also breastfeeding when I was diagnosed with a rare cancer. The docs also told me I should stop but no one really had a good reason. I tried to wean the baby but for some reason she would not take formula. So, I continued to breastfeed, worked with a lactation consultant managed my pain medications with a lot of advice. […] If you really want the help of someone who knows all about these issues I would search out a lactation consultant I know up in Canada they are a part of the medical system. You can probably get more info by calling the hospital maternity ward where you had the baby.

• #47 Cherry blossoms: a nursing mother’s journey with Paget’s Disease and triple-negative breast cancer – Our Milky Way

  https://www.ourmilkyway.org/cherry-blossoms-a-nursing-mothers-journey-with-pagets-disease-and-triple-negative-breast-cancer/

  Burkett, a former actor and the mother of three, was diagnosed with Paget’s Disease and triple-negative breast cancer when she was 37, her youngest child just two years old at the time. […] Well into their breastfeeding relationship, Burkett developed a sore on her nipple which she thought was a nursing sore. […] Burkett fashioned a bandaid over the still present sore, and during a routine physical, her physician questioned it. […] A biopsy confirmed her diagnoses– rare and often aggressive forms of cancer– just two weeks before she was supposed to start nursing school. […] Burkett opted for a bilateral mastectomy versus radiation and chemotherapy. […] Burkett has suffered complications from reconstructive surgery along with other challenges. […] Through the process, Burkett has found support through her friends and family.

• #48 Cherry blossoms: a nursing mother’s journey with Paget’s Disease and triple-negative breast cancer – Our Milky Way

  https://www.ourmilkyway.org/cherry-blossoms-a-nursing-mothers-journey-with-pagets-disease-and-triple-negative-breast-cancer/

  Burkett recently completed the Lactation Counselor Training Course (LCTC) after encouragement from a friend who is an IBCLC and through the suggestion of the LPN at her children’s pediatric office. […] Burkett, a true, tested warrior, is equipped with a passion for helping others and urges others to seek medical treatment if an abnormal condition persists over a month.

• #49 Paget Disease of the Breast in Pregnancy and Lactation – PubMed

  https://pubmed.ncbi.nlm.nih.gov/32816273/

  Paget’s disease of the breast (PDB) is a rare breast carcinoma believed to arise from an underlying in situ or invasive ductal cancer that migrates through the epidermis causing characteristic skin changes including scaling, redness, and itching of the nipple, areola, and sometimes the surrounding skin. […] The workup of Paget’s should focus on both making the diagnosis with nipple/skin scrape cytology or punch biopsy as well as evaluating any underlying mass with mammogram, breast ultrasound, and also a core needle biopsy, if required. […] Treatment focuses on management of the underlying breast cancer as usual. […] The purpose of this chapter is to describe the presentation of PDB as well as outline an approach to its diagnosis and management, especially in the setting of pregnancy and lactation.

• #50 Paget’s disease advice please – Ask the nurses – Cancer Chat | Cancer Research UK

  https://cancerchat.cancerresearchuk.org/f/ask-the-nurses/104765/paget-s-disease-advice-please

  I have just been told that I have Paget’s disease of the nipple along with DCIS and some more cancers in my breast and underarm. […] My question is how can I protect my nipple at present? It is sore and bleeding. Will it be ok to put a wound dressing over it? […] Put a non-adhesive dressing on your nipple held in place by your bra. You can get them in pharmacies, your local one might sell them singularly rather than a packet of them. […] Please get back to us if you need any more information or support. You may find it helpful to talk things through with one of the nurses on our helpline.

• #51 Paget’s disease of the breast | Speaking of Women’s Health

  https://speakingofwomenshealth.com/askthenurse/pagets-disease-of-the-breast

  You need to see a breast specialist if you think you have Pagets disease of the breast/nipple as this is a rare form of breast cancer. Please contact your PCP for a referral to a breast center or directly contact a breast specialist for an appointment as soon as possible. You will need to have a biopsy and treatment. […] You can apply olive oil to the dry skin.

• #52 Is There a New Kind of Breast Cancer?: Paget’s Disease – National Center for Health Research

  https://www.center4research.org/new-kind-breast-cancer-pagets-disease/

  The signs of Pagets disease include scaling and crusting lesions on the skin of the nipple or areola, discharge, nipple inversion, flattening of the nipple or a lump. […] Treatment of Pagets disease depends on how far the cancer has advanced. If there is no underlying cancer, only radiation may be necessary. DCIS or a small tumor may only require a lumpectomy, which is the removal of the lump plus the surrounding tissue. A larger tumor may require a mastectomy. […] A doctor may test for Pagets disease of the breast by a biopsy, by scraping cells from the affected area and examining them under a microscope, or by mammogram. It is recommended that women see a health care provider if they notice any lumps, sores, discharge or rashes, or if a rash on the breast does not clear up after treatment.

• #53 Paget’s disease advice please – Ask the nurses – Cancer Chat | Cancer Research UK

  https://cancerchat.cancerresearchuk.org/f/ask-the-nurses/104765/paget-s-disease-advice-please

  I have just been told that I have Paget’s disease of the nipple along with DCIS and some more cancers in my breast and underarm. […] My question is how can I protect my nipple at present? It is sore and bleeding. Will it be ok to put a wound dressing over it? […] Put a non-adhesive dressing on your nipple held in place by your bra. You can get them in pharmacies, your local one might sell them singularly rather than a packet of them. […] Please get back to us if you need any more information or support. You may find it helpful to talk things through with one of the nurses on our helpline.

• #54 Paget’s disease of the breast | Speaking of Women’s Health

  https://speakingofwomenshealth.com/askthenurse/pagets-disease-of-the-breast

  You need to see a breast specialist if you think you have Pagets disease of the breast/nipple as this is a rare form of breast cancer. Please contact your PCP for a referral to a breast center or directly contact a breast specialist for an appointment as soon as possible. You will need to have a biopsy and treatment. […] You can apply olive oil to the dry skin.

• #55 Paget’s disease advice please – Ask the nurses – Cancer Chat | Cancer Research UK

  https://cancerchat.cancerresearchuk.org/f/ask-the-nurses/104765/paget-s-disease-advice-please

  I have just been told that I have Paget’s disease of the nipple along with DCIS and some more cancers in my breast and underarm. […] My question is how can I protect my nipple at present? It is sore and bleeding. Will it be ok to put a wound dressing over it? […] Put a non-adhesive dressing on your nipple held in place by your bra. You can get them in pharmacies, your local one might sell them singularly rather than a packet of them. […] Please get back to us if you need any more information or support. You may find it helpful to talk things through with one of the nurses on our helpline.

• #56 Paget Disease of the Breast: Care Instructions | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.paget-disease-of-the-breast-care-instructions.uh4323

  Paget disease of the breast is a type of cancer. Breast cancer is the abnormal growth of cells in the breast. In Paget disease of the breast, some people notice a change in the skin of their nipple and the area around the nipple (areola). The skin can be reddish and scaly. Other people don’t notice any skin changes but do have pain, burning, or itching on their nipple. […] Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It’s also a good idea to know your test results and keep a list of the medicines you take. […] There are things you can do at home to help manage the symptoms of cancer and the side effects of treatment. Your doctor may also give you medicines to help with certain side effects. […] Watch closely for changes in your health, and be sure to contact your doctor if you have any symptoms that the cancer has come back or spread. These symptoms include: New lumps. Bone pain. Chest pain. Shortness of breath. Belly pain. Headaches that don’t go away.

• #57 Paget’s disease advice please – Ask the nurses – Cancer Chat | Cancer Research UK

  https://cancerchat.cancerresearchuk.org/f/ask-the-nurses/104765/paget-s-disease-advice-please

  I have just been told that I have Paget’s disease of the nipple along with DCIS and some more cancers in my breast and underarm. […] My question is how can I protect my nipple at present? It is sore and bleeding. Will it be ok to put a wound dressing over it? […] Put a non-adhesive dressing on your nipple held in place by your bra. You can get them in pharmacies, your local one might sell them singularly rather than a packet of them. […] Please get back to us if you need any more information or support. You may find it helpful to talk things through with one of the nurses on our helpline.

• #58 Paget’s Disease of the Breast: Stages, Symptoms & Prognosis

  https://my.clevelandclinic.org/health/diseases/17913-pagets-disease-of-the-breast

  Paget’s disease of the breast is a rare type of breast cancer that develops in the skin of the nipple. The primary treatment is surgery. […] Treatment involves surgery and sometimes additional cancer therapies. […] If you only have Paget’s disease of the breast, and no other tumors, you may have more minimal, breast-conserving surgery. […] After surgery, you’ll likely have additional, complementary treatments to prevent cancer from recurring. […] If you only have Paget’s disease of the nipple or ductal carcinoma in situ (stage 0) that hasn’t spread beyond the milk ducts, your prognosis is excellent. […] Always see your healthcare provider if you notice any changes in your breast, including skin conditions and changes under the skin. […] The best way to take care of yourself is to begin treatment as soon as possible.

• #59

  https://step2.medbullets.com/oncology/120426/paget-disease-of-the-breast

  Paget disease of the breast is a chronic, eczematous rash on the nipple and adjacent areolar skin. […] Symptoms include erythema, scaling, itching and burning sensation, ulceration, oozing, and bleeding. […] Physical exam shows an eczematous lesion involving the nipple and areolar areas. […] Surgical treatment includes mastectomy and lymph node dissection for patients with Paget disease of the breast and underlying invasive breast carcinoma. […] Prognosis is dependent upon the presence of the underlying invasive ductal carcinoma or axillary node metastases.

• #60 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Pagets-Disease-of-the-Nipple.aspx

  A sentinel lymph node biopsy is highly recommended for anyone with Paget disease of the nipple undergoing a mastectomy this will test for the spread of cancer to the axillary lymph nodes. A positive result from this will likely indicate the need for a more extensive surgical approach targeting the axillary lymph node. […] Recent studies have shown that breast-conserving surgery that includes removal of the nipple and areola, and subsequent whole-breast radiation therapy, is a viable and safe option for this cancer. This is provided that there is no palpable lump in the breast and tumor detected by mammogram. […] The prognosis depends greatly on the stage of cancer and additional characteristics of the breast tumor cells for example, the presence of hormone receptors for estrogen and progesterone would indicate a need for adjuvant therapy.

• #61 Paget’s disease of the nipple – PubMed

  https://pubmed.ncbi.nlm.nih.gov/19586431/

  Paget’s disease of the nipple is an unusual epidermal presentation of underlying breast cancer. It presents as eczematous change or erythematous ulceration, but may also be an incidental histological finding in a mastectomy specimen. Approximately half of the underlying cancers are invasive, the remainder being ductal carcinoma in situ, and only rarely is there no associated malignancy. Routine clinical and mammographic assessment may significantly underestimate the extent of disease, but MRI may increase the sensitivity in detecting occult malignancy. Mastectomy maximizes local control; however, selected cases can be treated by nipple conisation with radiotherapy. Sentinel node biopsy is the standard of care for axillary staging in the clinically and ultrasonically node-negative case. Almost all invasive cases overexpress human EGF receptor-2 and, therefore, are likely to benefit from adjuvant chemotherapy and herceptin.

• #62 Mammary Paget’s Disease: An Update

  https://www.mdpi.com/2072-6694/14/10/2422

  Total or skin-sparing mastectomy with surgical axillary staging with or without breast reconstruction is frequently performed for the treatment of MPD due to the frequency of multicentric or multifocal disease. […] Non-surgical or limited surgical approaches have also been utilized to manage MPD. […] In cases without evidence of underlying disease, non-operative management can offer an effective alternative therapy to traditional breast-conserving therapy. […] Nearly all patients diagnosed with MPD have either underlying invasive or intraductal carcinoma. […] In patients with MPD and no palpable or mammographic mass, the majority will have underlying DCIS; therefore, axillary lymph nodes are usually negative, and treatment should be limited to the breast. […] Without treatment, the skin lesions and underlying disease will progress to the development of invasive breast cancer, potentially followed by lymph node and visceral metastasis.

• #63 What Is Paget’s Disease of the Nipple? – Iowa Radiology

  https://www.iowaradiology.com/what-is-pagets-disease-of-the-nipple/

  Pagets disease, also called Pagets disease of the nipple or mammary Pagets disease (not to be confused with Pagets disease of the bone), is a rare form of breast cancer that accounts for about 1% of all breast cancer cases. […] Patients diagnosed with Pagets disease are usually found to have tumors in the same breast either ductal carcinoma in situ or invasive breast cancer. […] If Pagets disease is suspected, many doctors will begin by performing a physical exam. […] To diagnose Pagets disease, a biopsy will be taken of the nipple. […] Depending on the extent of the cancer, the presence or absence of additional cancers, and lymph node involvement, the treatment for Pagets disease can range from breast-conserving surgery, which includes removal of the nipple and areola followed by radiation treatment, to mastectomy. […] The prognosis for Pagets disease patients depends largely on whether an additional palpable breast tumor is present. […] As with any type of breast cancer, early detection, prompt treatment, and healthy habits are the keys to having the best possible chance of long-term survival.

• #64 Paget’s Disease of the Breast: Stages, Symptoms & Prognosis

  https://my.clevelandclinic.org/health/diseases/17913-pagets-disease-of-the-breast

  Paget’s disease of the breast is a rare type of breast cancer that develops in the skin of the nipple. The primary treatment is surgery. […] Treatment involves surgery and sometimes additional cancer therapies. […] If you only have Paget’s disease of the breast, and no other tumors, you may have more minimal, breast-conserving surgery. […] After surgery, you’ll likely have additional, complementary treatments to prevent cancer from recurring. […] If you only have Paget’s disease of the nipple or ductal carcinoma in situ (stage 0) that hasn’t spread beyond the milk ducts, your prognosis is excellent. […] Always see your healthcare provider if you notice any changes in your breast, including skin conditions and changes under the skin. […] The best way to take care of yourself is to begin treatment as soon as possible.

• #65 Paget’s Disease of the Breast: Symptoms, Causes, Diagnosis, Treatment, and Prevention

  https://www.everydayhealth.com/breast-cancer/guide/paget-disease/

  After the surgery, you may also need to have other treatments, called adjuvant therapy, to prevent the cancer from recurring. This may include radiation therapy, chemotherapy, and hormone therapy. […] If Pagets disease hasnt spread to the surrounding breast tissue, the prognosis is excellent. […] The overall five-year survival rate for women with Pagets was 82.6 percent. […] Pagets disease of the breast is a rare form of breast cancer that occurs in the nipple and usually the areola. Its oftentimes found alongside other forms of breast cancer, such as DCIS. If Pagets disease hasnt spread to other areas of the breast, it can likely be treated with surgery such as a lumpectomy, which can preserve some of the original breast tissue.

• #66 Paget’s Disease of the Breast: Symptoms, Causes, Diagnosis, Treatment, and Prevention

  https://www.everydayhealth.com/breast-cancer/guide/paget-disease/

  After the surgery, you may also need to have other treatments, called adjuvant therapy, to prevent the cancer from recurring. This may include radiation therapy, chemotherapy, and hormone therapy. […] If Pagets disease hasnt spread to the surrounding breast tissue, the prognosis is excellent. […] The overall five-year survival rate for women with Pagets was 82.6 percent. […] Pagets disease of the breast is a rare form of breast cancer that occurs in the nipple and usually the areola. Its oftentimes found alongside other forms of breast cancer, such as DCIS. If Pagets disease hasnt spread to other areas of the breast, it can likely be treated with surgery such as a lumpectomy, which can preserve some of the original breast tissue.

• #67 Paget’s disease of the breast: Causes, symptoms, treatment, and more

  https://www.medicalnewstoday.com/articles/192362

  If a person has any nipple or skin changes on the breast, they should tell a doctor right away, even if they think Pagets is unlikely. […] Pagets disease also will not respond to treatments for eczema. […] A person with this condition will need surgery whether or not they have underlying breast cancer. However, the type of surgery depends on each persons situation. […] For example, if cancer is present but only affects the nipple or the surrounding area, the doctor may suggest surgery to conserve the breast. […] After treatment finishes, it is essential to attend all follow-up appointments and to continue to monitor for changes. […] With early diagnosis and treatment, Pagets disease of the breast is typically curable.

• #68

  https://111.wales.nhs.uk/encyclopaedia/p/article/pagetsdiseaseofthenipple/

  Paget’s disease of the nipple, also known as Paget’s disease of the breast, is a rare condition associated with breast cancer. […] Paget’s disease of the nipple is usually associated with breast cancer. […] Surgery is the main treatment for Paget’s disease of the nipple. […] If Paget’s disease is detected and treated in its early stages, there’s a good chance of a full recovery. […] You should see your GP if you notice any changes in the skin of your nipple or areola. […] As Paget’s disease of the nipple is associated with breast cancer, the sooner it’s diagnosed, the better the outcome is likely to be. […] A biopsy is used to confirm a suspected diagnosis of Paget’s disease of the nipple. […] If you’re diagnosed with Paget’s disease of the nipple, surgery is often the first type of treatment you’ll receive.

• #69 Paget’s Disease of the Breast: Symptoms, Treatment, and More

  https://www.healthline.com/health/breast-cancer/pagets-disease-of-the-breast

  Surgery might be followed by radiation therapy to target any cancer cells that were missed. […] One potential complication of this type of breast cancer is that symptoms can be easily dismissed or misdiagnosed, delaying treatment. […] Breast cancer treatment can increase your long-term risk of a variety of conditions, such as lymphedema, due to removal of lymph nodes.

• #70 Paget’s Disease Of The Nipple: Symptoms And Diagnosis In Panama

  https://www.drrobertogarcia.com/en/pagets-disease-of-the-nipple-symptoms-and-diagnosis-in-panama/

  Did you know that a nipple change could be the key to detecting a little-known type of cancer? This condition, which is directly linked to breast tissue, is often mistaken for common irritations. In Panama, its timely detection makes the difference between effective treatment and serious complications. […] Early diagnosis is critical. Studies indicate that this condition mainly affects women over 50 years of age and is frequently associated with underlying carcinomas. Identifying changes in the texture, color or sensitivity of the nipple allows you to act before it progresses. […] Breast health education remains a challenge. Awareness campaigns and standardized care protocols could improve diagnosis times. Recognizing the particularities of this condition is key to optimizing results. […] In Panama, monthly self-exams and annual mammograms from the age of 40 are fundamental tools. If you notice changes in skin texture or unusual discharge, see your doctor immediately.

• #71 Paget’s Disease Of The Nipple: Symptoms And Diagnosis In Panama

  https://www.drrobertogarcia.com/en/pagets-disease-of-the-nipple-symptoms-and-diagnosis-in-panama/

  The skin of the nipple shows clear signs when something is not right. Scaly areas with irregular edges, similar to superficial burns, appear. Persistent redness and burning sensation often extend into the areola. […] For an accurate diagnosis, doctors combine three methods: Detailed physical exam of the entire breast, Biopsy of the affected cells, Mammography or MRI. […] The therapeutic approach for complex breast conditions combines technology and medical expertise. In Panama, updated protocols allow personalized strategies to be designed according to the needs of each patient. […] Comprehensive management requires coordination between surgeons, oncologists, and radiologists. This multidisciplinary approach ensures that each therapeutic phase is tailored to your clinical evolution. […] Identifying alterations in the breast requires constant attention. Studies confirm that 85% of cases detected in the early stages have a better prognosis. In Panama, combining healthy habits with regular medical checkups is the most effective strategy. […] Your active participation in the process makes all the difference.

• #72 Paget’s Disease Of The Nipple: Symptoms And Diagnosis In Panama

  https://www.drrobertogarcia.com/en/pagets-disease-of-the-nipple-symptoms-and-diagnosis-in-panama/

  The skin of the nipple shows clear signs when something is not right. Scaly areas with irregular edges, similar to superficial burns, appear. Persistent redness and burning sensation often extend into the areola. […] For an accurate diagnosis, doctors combine three methods: Detailed physical exam of the entire breast, Biopsy of the affected cells, Mammography or MRI. […] The therapeutic approach for complex breast conditions combines technology and medical expertise. In Panama, updated protocols allow personalized strategies to be designed according to the needs of each patient. […] Comprehensive management requires coordination between surgeons, oncologists, and radiologists. This multidisciplinary approach ensures that each therapeutic phase is tailored to your clinical evolution. […] Identifying alterations in the breast requires constant attention. Studies confirm that 85% of cases detected in the early stages have a better prognosis. In Panama, combining healthy habits with regular medical checkups is the most effective strategy. […] Your active participation in the process makes all the difference.

• #73 Cherry blossoms: a nursing mother’s journey with Paget’s Disease and triple-negative breast cancer – Our Milky Way

  https://www.ourmilkyway.org/cherry-blossoms-a-nursing-mothers-journey-with-pagets-disease-and-triple-negative-breast-cancer/

  Burkett recently completed the Lactation Counselor Training Course (LCTC) after encouragement from a friend who is an IBCLC and through the suggestion of the LPN at her children’s pediatric office. […] Burkett, a true, tested warrior, is equipped with a passion for helping others and urges others to seek medical treatment if an abnormal condition persists over a month.

• #74

  https://www.nursingcenter.com/journalarticle?Article_ID=5555113&Journal_ID=849729&Issue_ID=5555089

  ABSTRACT: Paget’s disease of the breast (PDB) is a rare disorder of the nipple-areola complex that may present clinically as a unilateral, eczematous, or ulcerated papule or plaque. This case highlights the importance of either punch or incisional wedge biopsy to establish a diagnosis of PDB for patients who present with chronic cutaneous changes of the nipple, areola, or skin of the breast, regardless of any previous normal mammogram or breast ultrasound. Mammography alone cannot rule out a diagnosis of PDB in a patient with cutaneous changes of the breast. […] PDB is characterized histologically by Paget cells in the nipple epidermis, which are thought to migrate there from breast carcinoma present in deeper ductal structures. […] Treatment and prognosis of PDB depend on the type of underlying associated breast carcinoma and presence or absence of axillary lymph node involvement. Treatment of PDB is typically composed of surgery, chemotherapy, or radiation therapy, either alone or in combination. Patients with PDB should be promptly referred to oncology for staging and treatment.

• #75

  https://www.nursingcenter.com/journalarticle?Article_ID=5555113&Journal_ID=849729&Issue_ID=5555089

  A full-thickness surgical punch or wedge biopsy is the gold standard to confirm or exclude a diagnosis of PDB. It is especially important to remember that patients who present with PDB isolated to the nipple and without a palpable breast mass may present with a normal mammogram despite presence of underlying IDC or ductal carcinoma in situ. Mammography has low sensitivity to detect PDB and should be used as a complimentary diagnostic tool to surgical wedge or punch biopsy when PDB is suspected.

• #76 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://www.jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  After surgery, radiation therapy and perhaps chemotherapy, targeted therapy, and/or hormone therapy may be recommended. About 97% of people diagnosed with Pagets disease of the nipple also have ductal carcinoma in situ or invasive cancer somewhere else in the breast. The exact treatment plan will depend on the characteristics of the underlying breast cancer such as stage, grade, and whether the cancer is hormone receptor-positive and/or HER2-positive. As in other breast cancer diagnoses and treatment, a consultation with a medical oncologist would be prudent. […] As with any breast cancer patient, the navigator plays an important role in the support and coordination of care. Patients with Pagets disease are no different. However, there are times when a patient may first be shaken by a diagnosis of cancer that might have been primarily treated as a dermatologic issue. After an introduction, the navigator should begin to establish a relationship of trust and empathy. This early introduction will allow for the coordination of care with the multidisciplinary team and give the patient confidence that the navigator will act as her advocate in all areas of treatment, which could lead to improved adherence to the care suggested.

• #77 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://www.jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  There is abundant literature about the navigation role and the positive impact it can have on patient outcomes and continuity of care. Despite the rarity of Pagets disease of the breast, the breast care navigators can validate their essential role as partner and advocate for patients at the most vulnerable of times.

• #78 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  The nurse navigator was an essential part of her cancer care team and was available for support, resources, and information. With the assistance of the navigator, the patient was prepared for surgery, referred to a support group, and given information on financial assistance. […] Patients with Pagets disease are no different. However, there are times when a patient may first be shaken by a diagnosis of cancer that might have been primarily treated as a dermatologic issue. After an introduction, the navigator should begin to establish a relationship of trust and empathy. This early introduction will allow for the coordination of care with the multidisciplinary team and give the patient confidence that the navigator will act as her advocate in all areas of treatment, which could lead to improved adherence to the care suggested.

• #79 Treatment options for Paget’s disease of the nipple | Cancer Australia

  https://www.canceraustralia.gov.au/cancer-types/breast-cancer/treatment-options/treatment-options-pagets-disease-nipple

  For women with Paget’s disease of the nipple, radiotherapy is almost always recommended after breast conserving surgery. […] Radiotherapy is sometimes recommended after mastectomy. […] For some women with Paget’s disease of the nipple, radiotherapy may be the only treatment needed after the biopsy used during diagnosis. […] Once treatment is finished, regular follow-up appointments with your specialist or general practitioner are recommended. […] Follow-up after treatment for Paget’s disease of the nipple usually involves a regular physical examination and an annual mammogram with or without an ultrasound. […] Breast care nurses specialise in caring for women with breast cancer and can be a valuable source of information and support.

• #80 Paget Disease of the Breast: Care Instructions | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.paget-disease-of-the-breast-care-instructions.uh4323

  Paget disease of the breast is a type of cancer. Breast cancer is the abnormal growth of cells in the breast. In Paget disease of the breast, some people notice a change in the skin of their nipple and the area around the nipple (areola). The skin can be reddish and scaly. Other people don’t notice any skin changes but do have pain, burning, or itching on their nipple. […] Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It’s also a good idea to know your test results and keep a list of the medicines you take. […] There are things you can do at home to help manage the symptoms of cancer and the side effects of treatment. Your doctor may also give you medicines to help with certain side effects. […] Watch closely for changes in your health, and be sure to contact your doctor if you have any symptoms that the cancer has come back or spread. These symptoms include: New lumps. Bone pain. Chest pain. Shortness of breath. Belly pain. Headaches that don’t go away.

• #81 Paget’s disease of the breast | Breast Cancer Now

  https://breastcancernow.org/about-breast-cancer/diagnosis/types-of-breast-cancer/pagets-disease-of-the-breast

  Pagets disease of the breast is an uncommon type of breast cancer. […] Its sometimes called Pagets disease of the nipple. […] Treatment aims to remove the area of Pagets disease from your breast and reduce the risk of it coming back or spreading to other parts of the body. […] Surgery is usually the first treatment for Pagets disease of the breast. […] If youve been diagnosed with Pagets disease alone, youre most likely to be offered surgery to remove your nipple and areola. […] You may also need to have surgery to your lymph nodes. […] Depending on the features of your Pagets disease, you may also be offered radiotherapy after your surgery. […] If you have invasive breast cancer in addition to Pagets disease, you may be given some treatments before surgery. […] You’ll usually continue to be monitored for 5 years after your hospital-based treatments (such as surgery or radiotherapy) finish. […] It’s important to be aware of any changes to your breast, chest or surrounding area. […] Most breast cancers dont come back after treatment. But sometimes it can return, so its important you know what signs and symptoms to look out for.

• #82 Paget Disease of the Breast: Care Instructions | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.paget-disease-of-the-breast-care-instructions.uh4323

  Paget disease of the breast is a type of cancer. Breast cancer is the abnormal growth of cells in the breast. In Paget disease of the breast, some people notice a change in the skin of their nipple and the area around the nipple (areola). The skin can be reddish and scaly. Other people don’t notice any skin changes but do have pain, burning, or itching on their nipple. […] Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It’s also a good idea to know your test results and keep a list of the medicines you take. […] There are things you can do at home to help manage the symptoms of cancer and the side effects of treatment. Your doctor may also give you medicines to help with certain side effects. […] Watch closely for changes in your health, and be sure to contact your doctor if you have any symptoms that the cancer has come back or spread. These symptoms include: New lumps. Bone pain. Chest pain. Shortness of breath. Belly pain. Headaches that don’t go away.

• #83 Paget’s disease of the breast | Breast cancer | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/breast-cancer/types/pagets-disease-breast

  You might have more treatment after surgery if you have Pagets disease with invasive breast cancer or DCIS. […] You usually have regular check ups after treatment for Pagets disease of the breast. […] Its important to remember that you can contact your doctor or specialist nurse if you notice a new symptom or have questions between your check ups. […] Coping with breast cancer can be difficult. There is help and support available to you and your family.

• #84 Paget’s Disease Of The Nipple: Symptoms And Diagnosis In Panama

  https://www.drrobertogarcia.com/en/pagets-disease-of-the-nipple-symptoms-and-diagnosis-in-panama/

  The skin of the nipple shows clear signs when something is not right. Scaly areas with irregular edges, similar to superficial burns, appear. Persistent redness and burning sensation often extend into the areola. […] For an accurate diagnosis, doctors combine three methods: Detailed physical exam of the entire breast, Biopsy of the affected cells, Mammography or MRI. […] The therapeutic approach for complex breast conditions combines technology and medical expertise. In Panama, updated protocols allow personalized strategies to be designed according to the needs of each patient. […] Comprehensive management requires coordination between surgeons, oncologists, and radiologists. This multidisciplinary approach ensures that each therapeutic phase is tailored to your clinical evolution. […] Identifying alterations in the breast requires constant attention. Studies confirm that 85% of cases detected in the early stages have a better prognosis. In Panama, combining healthy habits with regular medical checkups is the most effective strategy. […] Your active participation in the process makes all the difference.

• #85 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://www.jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  After surgery, radiation therapy and perhaps chemotherapy, targeted therapy, and/or hormone therapy may be recommended. About 97% of people diagnosed with Pagets disease of the nipple also have ductal carcinoma in situ or invasive cancer somewhere else in the breast. The exact treatment plan will depend on the characteristics of the underlying breast cancer such as stage, grade, and whether the cancer is hormone receptor-positive and/or HER2-positive. As in other breast cancer diagnoses and treatment, a consultation with a medical oncologist would be prudent. […] As with any breast cancer patient, the navigator plays an important role in the support and coordination of care. Patients with Pagets disease are no different. However, there are times when a patient may first be shaken by a diagnosis of cancer that might have been primarily treated as a dermatologic issue. After an introduction, the navigator should begin to establish a relationship of trust and empathy. This early introduction will allow for the coordination of care with the multidisciplinary team and give the patient confidence that the navigator will act as her advocate in all areas of treatment, which could lead to improved adherence to the care suggested.

• #86

  https://www.aurorahealthcare.org/services/cancer/breast-cancer/pagets-disease-breast

  Treating Paget’s disease of the breast typically involves addressing both the disease in the nipple area and any underlying breast cancer. The most common treatment for Pagets disease of the breast is surgery. […] Your care team at Aurora Health Care will use a collaborative approach to provide the best treatment possible. Supportive care services such as counseling, nutrition therapy, palliative care and physical therapy may also be offered to help you manage the physical and emotional challenges of cancer treatment.

• #87 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  The nurse navigator was an essential part of her cancer care team and was available for support, resources, and information. With the assistance of the navigator, the patient was prepared for surgery, referred to a support group, and given information on financial assistance. […] Patients with Pagets disease are no different. However, there are times when a patient may first be shaken by a diagnosis of cancer that might have been primarily treated as a dermatologic issue. After an introduction, the navigator should begin to establish a relationship of trust and empathy. This early introduction will allow for the coordination of care with the multidisciplinary team and give the patient confidence that the navigator will act as her advocate in all areas of treatment, which could lead to improved adherence to the care suggested.

• #88 Paget’s Disease of the Breast Explained

  https://resources.healthgrades.com/right-care/womens-health/pagets-disease-of-the-breast

  Your doctor will likely recommend follow-up treatment. Treatments may include radiation therapy, chemotherapy, or HRT. […] Paget’s disease of the breast is a rare form of cancer that affects the nipple and often the areola. Symptoms include redness, itching, and inflammation. For many females, it produces a lump in the breast. It can occur in males. However, it most commonly occurs in females over the age of 50. […] Typically, treatment for Paget’s disease can be effective. Options include breast surgery, radiation therapy, and HRT. Eating a healthy, balanced diet and regularly exercising can reduce the chance of having Paget’s disease or breast cancer.

• #89 Understanding Paget’s Disease Accompanied by Invasive Breast Cancer – Journal of Oncology Navigation & Survivorship

  https://www.jons-online.com/issues/2020/december-2020-vol-11-no-12/understanding-paget-s-disease-accompanied-by-invasive-breast-cancer

  There is abundant literature about the navigation role and the positive impact it can have on patient outcomes and continuity of care. Despite the rarity of Pagets disease of the breast, the breast care navigators can validate their essential role as partner and advocate for patients at the most vulnerable of times.

• #90 Paget’s disease of the breast: Causes, symptoms, treatment, and more

  https://www.medicalnewstoday.com/articles/192362

  If a person has any nipple or skin changes on the breast, they should tell a doctor right away, even if they think Pagets is unlikely. […] Pagets disease also will not respond to treatments for eczema. […] A person with this condition will need surgery whether or not they have underlying breast cancer. However, the type of surgery depends on each persons situation. […] For example, if cancer is present but only affects the nipple or the surrounding area, the doctor may suggest surgery to conserve the breast. […] After treatment finishes, it is essential to attend all follow-up appointments and to continue to monitor for changes. […] With early diagnosis and treatment, Pagets disease of the breast is typically curable.

• #91 Paget’s Disease of the Breast: Symptoms, Causes, Diagnosis, Treatment, and Prevention

  https://www.everydayhealth.com/breast-cancer/guide/paget-disease/

  After the surgery, you may also need to have other treatments, called adjuvant therapy, to prevent the cancer from recurring. This may include radiation therapy, chemotherapy, and hormone therapy. […] If Pagets disease hasnt spread to the surrounding breast tissue, the prognosis is excellent. […] The overall five-year survival rate for women with Pagets was 82.6 percent. […] Pagets disease of the breast is a rare form of breast cancer that occurs in the nipple and usually the areola. Its oftentimes found alongside other forms of breast cancer, such as DCIS. If Pagets disease hasnt spread to other areas of the breast, it can likely be treated with surgery such as a lumpectomy, which can preserve some of the original breast tissue.

• #92 Paget’s Disease of the Breast: Stages, Symptoms & Prognosis

  https://my.clevelandclinic.org/health/diseases/17913-pagets-disease-of-the-breast

  Paget’s disease of the breast is a rare type of breast cancer that develops in the skin of the nipple. The primary treatment is surgery. […] Treatment involves surgery and sometimes additional cancer therapies. […] If you only have Paget’s disease of the breast, and no other tumors, you may have more minimal, breast-conserving surgery. […] After surgery, you’ll likely have additional, complementary treatments to prevent cancer from recurring. […] If you only have Paget’s disease of the nipple or ductal carcinoma in situ (stage 0) that hasn’t spread beyond the milk ducts, your prognosis is excellent. […] Always see your healthcare provider if you notice any changes in your breast, including skin conditions and changes under the skin. […] The best way to take care of yourself is to begin treatment as soon as possible.

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