Materiały źródłowe

• #1 Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease | AAFP

  https://www.aafp.org/pubs/afp/issues/2008/1015/p961.html

  Systemic sclerosis (systemic scleroderma) is a chronic connective tissue disease of unknown etiology that causes widespread microvascular damage and excessive deposition of collagen in the skin and internal organs. […] Although no disease-modifying therapy has been proven effective, complications of systemic sclerosis are treatable, and interventions for organ-specific manifestations have improved substantially. Medications (e.g., calcium channel blockers and angiotensin-II receptor blockers for Raynaud phenomenon, appropriate treatments for gastroesophageal reflux disease) and lifestyle modifications can help prevent complications, such as digital ulcers and Barrett esophagus. […] The risk of renal damage from scleroderma renal crisis can be lessened by early detection, prompt initiation of angiotensin-converting enzyme inhibitor therapy, and avoidance of high-dose corticosteroids.

• #2 Preventative Care in Scleroderma: What is the best approach to bone health and cancer screening?

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10845237/

  Systemic sclerosis is a rare multi-system autoimmune disease characterized by fibrosis, vasculopathy, and autoimmunity. […] Patients with SSc have a greater risk of developing malignancies than the general population. Additionally, they are more likely to be vitamin D deficient and are at great risk of osteoporosis-related fractures. However, these complications can be addressed through preventative measures. The purpose of our review is to provide clinicians with an approach to bone health and cancer screening in SSc. […] Vitamin D deficiency may be more frequent in SSc patients. Vitamin D deficiency can lead to secondary hyperparathyroidism, mineralization defects, and low BMD which can ultimately precipitate osteopenia, OP, and fractures. […] A preventative care approach can help to ameliorate the effect of SSc-related complications such as osteoporosis and malignancies. Clinicians are encouraged to ensure vitamin D levels are in the normal range as some patients with SSc are at increased risk of deficiency despite supplementation. Furthermore, patients should be screened for malnutrition and patients identified at risk should undergo appropriate dietary interventions. Bone densities should be ordered using osteoporosis guidelines and treatment may be indicated in moderate to high risk patients. Lastly, given the increased risk of malignancies in SSc, patients should be regularly screened in accordance to their specific risk factors.

• #3 Scleroderma: Symptoms, Causes & Treatment Options

  https://my.clevelandclinic.org/health/diseases/scleroderma

  Because experts dont know what causes it, theres no way to prevent scleroderma. […] You should expect to manage scleroderma and its symptoms for the rest of your life. Even though theres no cure, most people find treatments and lifestyle tweaks to minimize how much their symptoms impact their day-to-day lives.

• #4 Scleroderma Guide: Causes, Symptoms and Treatment Options

  https://www.drugs.com/health-guide/scleroderma.html

  There is no way to prevent scleroderma.

• #5 Scleroderma Causes, Symptoms, Treatment, Medications, Prevention

  https://www.medicinenet.com/scleroderma/article.htm

  Is it possible to prevent scleroderma? There is no prevention method or diet to avoid or decrease the risk of scleroderma.

• #6 Systemic Sclerosis Treatment: Experts Provide a New Framework – Rheumatology Advisor

  https://www.rheumatologyadvisor.com/home/topics/scleroderma/experts-provide-new-framework-for-systemic-sclerosis-treatment/

  Data show that delayed treatment is common in SSc. Identification of these underlying signs offers an opportunity for improved therapeutic outcomes with earlier diagnosis, whereby many SSc-related vascular, cardiac, gastrointestinal, nutritional, and musculoskeletal complications can be treated and even prevented. […] Preventing death and permanent disability in systemic sclerosis is accomplished with early and appropriate treatment, the authors wrote, noting that a major obstacle is posed by the challenges to positively differentiating between earlier states of active progressive disease and the later transformation to fibrotic damage. […] The new framework recommends a comprehensive and interactional approach between providers of multiple disciplines in order to optimally manage the disease over time. Sharing care between recognised SSc centers and local cardiology/pulmonary/rheumatology/gastroenterology colleagues may prevent complications and poor outcomes, while providing support to local specialists.

• #7 Fast-forward to 2040: What does the future hold for Scleroderma? | SRUK

  https://www.sruk.co.uk/about-us/news/fast-forward-2040-what-does-future-hold-scleroderm/

  Scleroderma is a complex, chronic and progressive condition, overactive inflammatory responses lead to damage and scarring affecting the skin and other organs of the body eventually leading to irreversible damage. Professor Francesco Del Galdo envisages a future where people with scleroderma will be diagnosed earlier allowing doctors to prevent these irreversible changes occurring. […] Professor Del Galdo believes that this work will contribute to a future paradigm shift: Patients with Raynauds will be tested for their risk of autoimmunity. For those in higher and medium risk categories, regular monitoring for signs of biological activity (early symptoms of scleroderma) will be conducted and individuals may be offered treatments to help manage these processes. […] Finally, Professor Del Galdo hopes that in the future, patients will only receive a clinical diagnosis of scleroderma is all attempts to prevent the condition have been unsuccessful. This prevention work could be initiated before the patient has even been diagnosed with scleroderma, through the monitoring of their biological activity (otherwise known as the processes which underlie autoimmunity).

• #8 Fast-forward to 2040: What does the future hold for Scleroderma? | SRUK

  https://www.sruk.co.uk/about-us/news/fast-forward-2040-what-does-future-hold-scleroderm/

  Scleroderma is a complex, chronic and progressive condition, overactive inflammatory responses lead to damage and scarring affecting the skin and other organs of the body eventually leading to irreversible damage. Professor Francesco Del Galdo envisages a future where people with scleroderma will be diagnosed earlier allowing doctors to prevent these irreversible changes occurring. […] Professor Del Galdo believes that this work will contribute to a future paradigm shift: Patients with Raynauds will be tested for their risk of autoimmunity. For those in higher and medium risk categories, regular monitoring for signs of biological activity (early symptoms of scleroderma) will be conducted and individuals may be offered treatments to help manage these processes. […] Finally, Professor Del Galdo hopes that in the future, patients will only receive a clinical diagnosis of scleroderma is all attempts to prevent the condition have been unsuccessful. This prevention work could be initiated before the patient has even been diagnosed with scleroderma, through the monitoring of their biological activity (otherwise known as the processes which underlie autoimmunity).

• #9 Fast-forward to 2040: What does the future hold for Scleroderma? | SRUK

  https://www.sruk.co.uk/about-us/news/fast-forward-2040-what-does-future-hold-scleroderm/

  Dr Elizabeth Volkmann is interested in developing personalized treatment approaches which aim to treat or prevent organ involvement before it begins. […] This knowledge would allow clinicians to step in ahead of time with treatments or nutritional interventions to prevent these sometimes-fatal complications from developing.

• #10 Fast-forward to 2040: What does the future hold for Scleroderma? | SRUK

  https://www.sruk.co.uk/about-us/news/fast-forward-2040-what-does-future-hold-scleroderm/

  Dr Elizabeth Volkmann is interested in developing personalized treatment approaches which aim to treat or prevent organ involvement before it begins. […] This knowledge would allow clinicians to step in ahead of time with treatments or nutritional interventions to prevent these sometimes-fatal complications from developing.

• #11 Scleroderma – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/scleroderma/diagnosis-treatment/drc-20351957

  There is no treatment that can cure or stop the overproduction of collagen that happens in scleroderma. But a variety of treatments can help control symptoms and prevent complications. […] Recommended vaccinations are important to protect people with scleroderma from infectious diseases. Talk with your healthcare professional about vaccines for influenza, pneumonia, shingles, HPV, COVID-19 and RSV. […] You can take a number of steps to help manage your symptoms of scleroderma: Stay active. Exercise keeps your body flexible, improves circulation and eases stiffness. […] Protect yourself from the cold. Wear warm mittens for protection anytime your hands are exposed to cold even when you reach into a freezer. It also is important to keep your core body temperature warm to help prevent Raynaud’s phenomenon.

• #12 Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease | AAFP

  https://www.aafp.org/pubs/afp/issues/2008/1015/p961.html

  Systemic sclerosis (systemic scleroderma) is a chronic connective tissue disease of unknown etiology that causes widespread microvascular damage and excessive deposition of collagen in the skin and internal organs. […] Although no disease-modifying therapy has been proven effective, complications of systemic sclerosis are treatable, and interventions for organ-specific manifestations have improved substantially. Medications (e.g., calcium channel blockers and angiotensin-II receptor blockers for Raynaud phenomenon, appropriate treatments for gastroesophageal reflux disease) and lifestyle modifications can help prevent complications, such as digital ulcers and Barrett esophagus. […] The risk of renal damage from scleroderma renal crisis can be lessened by early detection, prompt initiation of angiotensin-converting enzyme inhibitor therapy, and avoidance of high-dose corticosteroids.

• #13 Systemic Sclerosis Treatment: Experts Provide a New Framework – Rheumatology Advisor

  https://www.rheumatologyadvisor.com/home/topics/scleroderma/experts-provide-new-framework-for-systemic-sclerosis-treatment/

  Data show that delayed treatment is common in SSc. Identification of these underlying signs offers an opportunity for improved therapeutic outcomes with earlier diagnosis, whereby many SSc-related vascular, cardiac, gastrointestinal, nutritional, and musculoskeletal complications can be treated and even prevented. […] Preventing death and permanent disability in systemic sclerosis is accomplished with early and appropriate treatment, the authors wrote, noting that a major obstacle is posed by the challenges to positively differentiating between earlier states of active progressive disease and the later transformation to fibrotic damage. […] The new framework recommends a comprehensive and interactional approach between providers of multiple disciplines in order to optimally manage the disease over time. Sharing care between recognised SSc centers and local cardiology/pulmonary/rheumatology/gastroenterology colleagues may prevent complications and poor outcomes, while providing support to local specialists.

• #14 Scleroderma – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/scleroderma/diagnosis-treatment/drc-20351957

  There is no treatment that can cure or stop the overproduction of collagen that happens in scleroderma. But a variety of treatments can help control symptoms and prevent complications. […] Recommended vaccinations are important to protect people with scleroderma from infectious diseases. Talk with your healthcare professional about vaccines for influenza, pneumonia, shingles, HPV, COVID-19 and RSV. […] You can take a number of steps to help manage your symptoms of scleroderma: Stay active. Exercise keeps your body flexible, improves circulation and eases stiffness. […] Protect yourself from the cold. Wear warm mittens for protection anytime your hands are exposed to cold even when you reach into a freezer. It also is important to keep your core body temperature warm to help prevent Raynaud’s phenomenon.

• #15 Scleroderma Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/condition/scleroderma

  Although no one knows how to prevent scleroderma, you can take steps to avoid getting infections when you have scleroderma. Your doctor may recommend: […] Pneumonia (pneumococcal) vaccine […] Annual flu vaccine.

• #16 Scleroderma | Condition | UT Southwestern Medical Center

  https://utswmed.org/conditions-treatments/scleroderma-systemic-sclerosis/

  Although there is no cure for systemic sclerosis, treatments using the most advanced therapeutic techniques available aim to help reduce symptoms, slow the progression of the disease, and help prevent complications. […] UT Southwestern rheumatologists work to develop treatment plans tailored to each patients specific needs. Treatment options include: […] Flu and pneumonia vaccines.

• #17 Scleroderma – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/scleroderma/diagnosis-treatment/drc-20351957

  There is no treatment that can cure or stop the overproduction of collagen that happens in scleroderma. But a variety of treatments can help control symptoms and prevent complications. […] Recommended vaccinations are important to protect people with scleroderma from infectious diseases. Talk with your healthcare professional about vaccines for influenza, pneumonia, shingles, HPV, COVID-19 and RSV. […] You can take a number of steps to help manage your symptoms of scleroderma: Stay active. Exercise keeps your body flexible, improves circulation and eases stiffness. […] Protect yourself from the cold. Wear warm mittens for protection anytime your hands are exposed to cold even when you reach into a freezer. It also is important to keep your core body temperature warm to help prevent Raynaud’s phenomenon.

• #18 Scleroderma Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/condition/scleroderma

  Although no one knows how to prevent scleroderma, you can take steps to avoid getting infections when you have scleroderma. Your doctor may recommend: […] Pneumonia (pneumococcal) vaccine […] Annual flu vaccine.

• #19 Scleroderma – symptoms, causes and treatment | healthdirect

  https://www.healthdirect.gov.au/scleroderma

  Can scleroderma be prevented? […] It’s currently not possible to prevent scleroderma. […] You can help prevent complications from Raynaud phenomenon by: stopping smoking, avoiding getting cold, reducing stress.

• #20 Scleroderma – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/scleroderma/diagnosis-treatment/drc-20351957

  There is no treatment that can cure or stop the overproduction of collagen that happens in scleroderma. But a variety of treatments can help control symptoms and prevent complications. […] Recommended vaccinations are important to protect people with scleroderma from infectious diseases. Talk with your healthcare professional about vaccines for influenza, pneumonia, shingles, HPV, COVID-19 and RSV. […] You can take a number of steps to help manage your symptoms of scleroderma: Stay active. Exercise keeps your body flexible, improves circulation and eases stiffness. […] Protect yourself from the cold. Wear warm mittens for protection anytime your hands are exposed to cold even when you reach into a freezer. It also is important to keep your core body temperature warm to help prevent Raynaud’s phenomenon.

• #21 Scleroderma – symptoms, causes and treatment | healthdirect

  https://www.healthdirect.gov.au/scleroderma

  Can scleroderma be prevented? […] It’s currently not possible to prevent scleroderma. […] You can help prevent complications from Raynaud phenomenon by: stopping smoking, avoiding getting cold, reducing stress.

• #22 CREST Syndrome Treatment & Management: Medical Care, Surgical Care, Consultations

  https://emedicine.medscape.com/article/1064663-treatment

  Reinforce the wearing of gloves, a hat, and a coat outdoors and, if necessary, indoors; emphasize the importance of the keeping core body and hand temperature elevated. […] Counsel patients to stop smoking. […] Emphasize behavior changes (eg, weight loss; elevating head of bed; reduction of caffeine, tobacco, alcohol, and chocolate intake and avoidance prior to recumbency; eating small meals; waiting 3-4 h after eating before lying down).

• #23 Scleroderma: Causes, Symptoms, Treatments, and Prevention Guide

  https://www.apollo247.com/blog/article/scleroderma-definition-causes-symptoms-treatment-prevention

  Living with Scleroderma involves not only medical treatments but also adopting a healthy lifestyle to manage symptoms and improve overall well-being. […] Regular Exercise and Stretching […] Exercise and stretching can help maintain joint flexibility, muscle strength, and overall mobility. Low-impact activities like walking, swimming, and gentle yoga are often recommended. […] Proper Skin Care and Protection from UV Rays […] Since scleroderma can make the skin more sensitive, it’s crucial to protect it from excessive sun exposure. Use sunscreen with a high SPF, wear protective clothing, and avoid prolonged sun exposure to prevent skin damage. […] Quitting Smoking and Avoiding Second-hand Smoke […] Smoking can worsen the symptoms of scleroderma and increase the risk of vascular complications. Quitting smoking and avoiding second-hand smoke exposure are essential for managing the disease. […] Balanced Diet and Healthy Eating Habits […] A well-balanced diet can support overall health and help manage specific symptoms. […] Limit processed foods and high-fat foods as these can exacerbate symptoms and negatively affect overall health.

• #24 Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease | AAFP

  https://www.aafp.org/pubs/afp/issues/2008/1015/p961.html

  Systemic sclerosis (systemic scleroderma) is a chronic connective tissue disease of unknown etiology that causes widespread microvascular damage and excessive deposition of collagen in the skin and internal organs. […] Although no disease-modifying therapy has been proven effective, complications of systemic sclerosis are treatable, and interventions for organ-specific manifestations have improved substantially. Medications (e.g., calcium channel blockers and angiotensin-II receptor blockers for Raynaud phenomenon, appropriate treatments for gastroesophageal reflux disease) and lifestyle modifications can help prevent complications, such as digital ulcers and Barrett esophagus. […] The risk of renal damage from scleroderma renal crisis can be lessened by early detection, prompt initiation of angiotensin-converting enzyme inhibitor therapy, and avoidance of high-dose corticosteroids.

• #25 Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease | AAFP

  https://www.aafp.org/pubs/afp/issues/2008/1015/p961.html

  Systemic sclerosis (systemic scleroderma) is a chronic connective tissue disease of unknown etiology that causes widespread microvascular damage and excessive deposition of collagen in the skin and internal organs. […] Although no disease-modifying therapy has been proven effective, complications of systemic sclerosis are treatable, and interventions for organ-specific manifestations have improved substantially. Medications (e.g., calcium channel blockers and angiotensin-II receptor blockers for Raynaud phenomenon, appropriate treatments for gastroesophageal reflux disease) and lifestyle modifications can help prevent complications, such as digital ulcers and Barrett esophagus. […] The risk of renal damage from scleroderma renal crisis can be lessened by early detection, prompt initiation of angiotensin-converting enzyme inhibitor therapy, and avoidance of high-dose corticosteroids.

• #26 Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease | AAFP

  https://www.aafp.org/pubs/afp/issues/2008/1015/p961.html

  Systemic sclerosis (systemic scleroderma) is a chronic connective tissue disease of unknown etiology that causes widespread microvascular damage and excessive deposition of collagen in the skin and internal organs. […] Although no disease-modifying therapy has been proven effective, complications of systemic sclerosis are treatable, and interventions for organ-specific manifestations have improved substantially. Medications (e.g., calcium channel blockers and angiotensin-II receptor blockers for Raynaud phenomenon, appropriate treatments for gastroesophageal reflux disease) and lifestyle modifications can help prevent complications, such as digital ulcers and Barrett esophagus. […] The risk of renal damage from scleroderma renal crisis can be lessened by early detection, prompt initiation of angiotensin-converting enzyme inhibitor therapy, and avoidance of high-dose corticosteroids.

• #27 Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease | AAFP

  https://www.aafp.org/pubs/afp/issues/2008/1015/p961.html

  Optimal patient care includes an integrated, multidisciplinary approach to promptly and effectively recognize, evaluate, and manage complications and limit end-organ dysfunction. […] Regular blood pressure monitoring is essential for early detection of scleroderma renal crisis. […] All patients with systemic sclerosis should be advised to check their blood pressure at home on a regular basis. Any persistent elevations should prompt a medical evaluation and treatment with ACE inhibitors if scleroderma renal crisis is suspected. ACE inhibitors should be used to control hypertension despite rising serum creatinine levels or the initiation of dialysis because they are essential for preserving and restoring renal function.

• #28 Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease | AAFP

  https://www.aafp.org/pubs/afp/issues/2008/1015/p961.html

  Optimal patient care includes an integrated, multidisciplinary approach to promptly and effectively recognize, evaluate, and manage complications and limit end-organ dysfunction. […] Regular blood pressure monitoring is essential for early detection of scleroderma renal crisis. […] All patients with systemic sclerosis should be advised to check their blood pressure at home on a regular basis. Any persistent elevations should prompt a medical evaluation and treatment with ACE inhibitors if scleroderma renal crisis is suspected. ACE inhibitors should be used to control hypertension despite rising serum creatinine levels or the initiation of dialysis because they are essential for preserving and restoring renal function.

• #29 Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease | AAFP

  https://www.aafp.org/pubs/afp/issues/2008/1015/p961.html

  Systemic sclerosis (systemic scleroderma) is a chronic connective tissue disease of unknown etiology that causes widespread microvascular damage and excessive deposition of collagen in the skin and internal organs. […] Although no disease-modifying therapy has been proven effective, complications of systemic sclerosis are treatable, and interventions for organ-specific manifestations have improved substantially. Medications (e.g., calcium channel blockers and angiotensin-II receptor blockers for Raynaud phenomenon, appropriate treatments for gastroesophageal reflux disease) and lifestyle modifications can help prevent complications, such as digital ulcers and Barrett esophagus. […] The risk of renal damage from scleroderma renal crisis can be lessened by early detection, prompt initiation of angiotensin-converting enzyme inhibitor therapy, and avoidance of high-dose corticosteroids.

• #30 CREST Syndrome Treatment & Management: Medical Care, Surgical Care, Consultations

  https://emedicine.medscape.com/article/1064663-treatment

  Reinforce the wearing of gloves, a hat, and a coat outdoors and, if necessary, indoors; emphasize the importance of the keeping core body and hand temperature elevated. […] Counsel patients to stop smoking. […] Emphasize behavior changes (eg, weight loss; elevating head of bed; reduction of caffeine, tobacco, alcohol, and chocolate intake and avoidance prior to recumbency; eating small meals; waiting 3-4 h after eating before lying down).

• #31 CREST Syndrome Treatment & Management: Medical Care, Surgical Care, Consultations

  https://emedicine.medscape.com/article/1064663-treatment

  Reinforce the wearing of gloves, a hat, and a coat outdoors and, if necessary, indoors; emphasize the importance of the keeping core body and hand temperature elevated. […] Counsel patients to stop smoking. […] Emphasize behavior changes (eg, weight loss; elevating head of bed; reduction of caffeine, tobacco, alcohol, and chocolate intake and avoidance prior to recumbency; eating small meals; waiting 3-4 h after eating before lying down).

• #32 Preventative Care in Scleroderma: What is the best approach to bone health and cancer screening?

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10845237/

  Systemic sclerosis is a rare multi-system autoimmune disease characterized by fibrosis, vasculopathy, and autoimmunity. […] Patients with SSc have a greater risk of developing malignancies than the general population. Additionally, they are more likely to be vitamin D deficient and are at great risk of osteoporosis-related fractures. However, these complications can be addressed through preventative measures. The purpose of our review is to provide clinicians with an approach to bone health and cancer screening in SSc. […] Vitamin D deficiency may be more frequent in SSc patients. Vitamin D deficiency can lead to secondary hyperparathyroidism, mineralization defects, and low BMD which can ultimately precipitate osteopenia, OP, and fractures. […] A preventative care approach can help to ameliorate the effect of SSc-related complications such as osteoporosis and malignancies. Clinicians are encouraged to ensure vitamin D levels are in the normal range as some patients with SSc are at increased risk of deficiency despite supplementation. Furthermore, patients should be screened for malnutrition and patients identified at risk should undergo appropriate dietary interventions. Bone densities should be ordered using osteoporosis guidelines and treatment may be indicated in moderate to high risk patients. Lastly, given the increased risk of malignancies in SSc, patients should be regularly screened in accordance to their specific risk factors.

• #33 Preventative Care in Scleroderma: What is the best approach to bone health and cancer screening?

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10845237/

  Systemic sclerosis is a rare multi-system autoimmune disease characterized by fibrosis, vasculopathy, and autoimmunity. […] Patients with SSc have a greater risk of developing malignancies than the general population. Additionally, they are more likely to be vitamin D deficient and are at great risk of osteoporosis-related fractures. However, these complications can be addressed through preventative measures. The purpose of our review is to provide clinicians with an approach to bone health and cancer screening in SSc. […] Vitamin D deficiency may be more frequent in SSc patients. Vitamin D deficiency can lead to secondary hyperparathyroidism, mineralization defects, and low BMD which can ultimately precipitate osteopenia, OP, and fractures. […] A preventative care approach can help to ameliorate the effect of SSc-related complications such as osteoporosis and malignancies. Clinicians are encouraged to ensure vitamin D levels are in the normal range as some patients with SSc are at increased risk of deficiency despite supplementation. Furthermore, patients should be screened for malnutrition and patients identified at risk should undergo appropriate dietary interventions. Bone densities should be ordered using osteoporosis guidelines and treatment may be indicated in moderate to high risk patients. Lastly, given the increased risk of malignancies in SSc, patients should be regularly screened in accordance to their specific risk factors.

• #34 Preventative Care in Scleroderma: What is the best approach to bone health and cancer screening?

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10845237/

  Systemic sclerosis is a rare multi-system autoimmune disease characterized by fibrosis, vasculopathy, and autoimmunity. […] Patients with SSc have a greater risk of developing malignancies than the general population. Additionally, they are more likely to be vitamin D deficient and are at great risk of osteoporosis-related fractures. However, these complications can be addressed through preventative measures. The purpose of our review is to provide clinicians with an approach to bone health and cancer screening in SSc. […] Vitamin D deficiency may be more frequent in SSc patients. Vitamin D deficiency can lead to secondary hyperparathyroidism, mineralization defects, and low BMD which can ultimately precipitate osteopenia, OP, and fractures. […] A preventative care approach can help to ameliorate the effect of SSc-related complications such as osteoporosis and malignancies. Clinicians are encouraged to ensure vitamin D levels are in the normal range as some patients with SSc are at increased risk of deficiency despite supplementation. Furthermore, patients should be screened for malnutrition and patients identified at risk should undergo appropriate dietary interventions. Bone densities should be ordered using osteoporosis guidelines and treatment may be indicated in moderate to high risk patients. Lastly, given the increased risk of malignancies in SSc, patients should be regularly screened in accordance to their specific risk factors.

• #35 Preventative Care in Scleroderma: What is the best approach to bone health and cancer screening?

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10845237/

  Systemic sclerosis is a rare multi-system autoimmune disease characterized by fibrosis, vasculopathy, and autoimmunity. […] Patients with SSc have a greater risk of developing malignancies than the general population. Additionally, they are more likely to be vitamin D deficient and are at great risk of osteoporosis-related fractures. However, these complications can be addressed through preventative measures. The purpose of our review is to provide clinicians with an approach to bone health and cancer screening in SSc. […] Vitamin D deficiency may be more frequent in SSc patients. Vitamin D deficiency can lead to secondary hyperparathyroidism, mineralization defects, and low BMD which can ultimately precipitate osteopenia, OP, and fractures. […] A preventative care approach can help to ameliorate the effect of SSc-related complications such as osteoporosis and malignancies. Clinicians are encouraged to ensure vitamin D levels are in the normal range as some patients with SSc are at increased risk of deficiency despite supplementation. Furthermore, patients should be screened for malnutrition and patients identified at risk should undergo appropriate dietary interventions. Bone densities should be ordered using osteoporosis guidelines and treatment may be indicated in moderate to high risk patients. Lastly, given the increased risk of malignancies in SSc, patients should be regularly screened in accordance to their specific risk factors.

• #36 Scleroderma: Causes, Symptoms, Treatments, and Prevention Guide

  https://www.apollo247.com/blog/article/scleroderma-definition-causes-symptoms-treatment-prevention

  Living with Scleroderma involves not only medical treatments but also adopting a healthy lifestyle to manage symptoms and improve overall well-being. […] Regular Exercise and Stretching […] Exercise and stretching can help maintain joint flexibility, muscle strength, and overall mobility. Low-impact activities like walking, swimming, and gentle yoga are often recommended. […] Proper Skin Care and Protection from UV Rays […] Since scleroderma can make the skin more sensitive, it’s crucial to protect it from excessive sun exposure. Use sunscreen with a high SPF, wear protective clothing, and avoid prolonged sun exposure to prevent skin damage. […] Quitting Smoking and Avoiding Second-hand Smoke […] Smoking can worsen the symptoms of scleroderma and increase the risk of vascular complications. Quitting smoking and avoiding second-hand smoke exposure are essential for managing the disease. […] Balanced Diet and Healthy Eating Habits […] A well-balanced diet can support overall health and help manage specific symptoms. […] Limit processed foods and high-fat foods as these can exacerbate symptoms and negatively affect overall health.

• #37 Scleroderma – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/scleroderma/diagnosis-treatment/drc-20351957

  There is no treatment that can cure or stop the overproduction of collagen that happens in scleroderma. But a variety of treatments can help control symptoms and prevent complications. […] Recommended vaccinations are important to protect people with scleroderma from infectious diseases. Talk with your healthcare professional about vaccines for influenza, pneumonia, shingles, HPV, COVID-19 and RSV. […] You can take a number of steps to help manage your symptoms of scleroderma: Stay active. Exercise keeps your body flexible, improves circulation and eases stiffness. […] Protect yourself from the cold. Wear warm mittens for protection anytime your hands are exposed to cold even when you reach into a freezer. It also is important to keep your core body temperature warm to help prevent Raynaud’s phenomenon.

• #38 Scleroderma: Causes, Symptoms, Treatments, and Prevention Guide

  https://www.apollo247.com/blog/article/scleroderma-definition-causes-symptoms-treatment-prevention

  Living with Scleroderma involves not only medical treatments but also adopting a healthy lifestyle to manage symptoms and improve overall well-being. […] Regular Exercise and Stretching […] Exercise and stretching can help maintain joint flexibility, muscle strength, and overall mobility. Low-impact activities like walking, swimming, and gentle yoga are often recommended. […] Proper Skin Care and Protection from UV Rays […] Since scleroderma can make the skin more sensitive, it’s crucial to protect it from excessive sun exposure. Use sunscreen with a high SPF, wear protective clothing, and avoid prolonged sun exposure to prevent skin damage. […] Quitting Smoking and Avoiding Second-hand Smoke […] Smoking can worsen the symptoms of scleroderma and increase the risk of vascular complications. Quitting smoking and avoiding second-hand smoke exposure are essential for managing the disease. […] Balanced Diet and Healthy Eating Habits […] A well-balanced diet can support overall health and help manage specific symptoms. […] Limit processed foods and high-fat foods as these can exacerbate symptoms and negatively affect overall health.

• #39 How can I prevent scleroderma? – HealthyWomen

  https://www.healthywomen.org/ask-expert/how-can-i-prevent-scleroderma

  No one really knows enough about scleroderma to know whether there is a way to prevent the disease or delay its onset. […] Although clear-cut guidance on prevention is lacking, there are measures you can take to prevent or lessen the symptoms if you have been diagnosed with scleroderma. […] Dental care is essential. […] Regular exercise or stretching can maintain joint flexibility and help keep your skin pliable. […] Other strategies include frequent massage of the skin and avoidance of detergent soaps, which dry the skin. […] Frequent use of bath oils and moisturizing lotions or ointments can help soften the skin, and a cold-water room humidifier can keep your skin moist. […] Reducing stress is critical, and some experts suggest biofeedback training to reduce pain and promote relaxation. […] Joining a scleroderma support group can also help.

• #40 Scleroderma: Causes, Symptoms, Treatments, and Prevention Guide

  https://www.apollo247.com/blog/article/scleroderma-definition-causes-symptoms-treatment-prevention

  Living with Scleroderma involves not only medical treatments but also adopting a healthy lifestyle to manage symptoms and improve overall well-being. […] Regular Exercise and Stretching […] Exercise and stretching can help maintain joint flexibility, muscle strength, and overall mobility. Low-impact activities like walking, swimming, and gentle yoga are often recommended. […] Proper Skin Care and Protection from UV Rays […] Since scleroderma can make the skin more sensitive, it’s crucial to protect it from excessive sun exposure. Use sunscreen with a high SPF, wear protective clothing, and avoid prolonged sun exposure to prevent skin damage. […] Quitting Smoking and Avoiding Second-hand Smoke […] Smoking can worsen the symptoms of scleroderma and increase the risk of vascular complications. Quitting smoking and avoiding second-hand smoke exposure are essential for managing the disease. […] Balanced Diet and Healthy Eating Habits […] A well-balanced diet can support overall health and help manage specific symptoms. […] Limit processed foods and high-fat foods as these can exacerbate symptoms and negatively affect overall health.

• #41 How can I prevent scleroderma? – HealthyWomen

  https://www.healthywomen.org/ask-expert/how-can-i-prevent-scleroderma

  No one really knows enough about scleroderma to know whether there is a way to prevent the disease or delay its onset. […] Although clear-cut guidance on prevention is lacking, there are measures you can take to prevent or lessen the symptoms if you have been diagnosed with scleroderma. […] Dental care is essential. […] Regular exercise or stretching can maintain joint flexibility and help keep your skin pliable. […] Other strategies include frequent massage of the skin and avoidance of detergent soaps, which dry the skin. […] Frequent use of bath oils and moisturizing lotions or ointments can help soften the skin, and a cold-water room humidifier can keep your skin moist. […] Reducing stress is critical, and some experts suggest biofeedback training to reduce pain and promote relaxation. […] Joining a scleroderma support group can also help.

• #42 How can I prevent scleroderma? – HealthyWomen

  https://www.healthywomen.org/ask-expert/how-can-i-prevent-scleroderma

  No one really knows enough about scleroderma to know whether there is a way to prevent the disease or delay its onset. […] Although clear-cut guidance on prevention is lacking, there are measures you can take to prevent or lessen the symptoms if you have been diagnosed with scleroderma. […] Dental care is essential. […] Regular exercise or stretching can maintain joint flexibility and help keep your skin pliable. […] Other strategies include frequent massage of the skin and avoidance of detergent soaps, which dry the skin. […] Frequent use of bath oils and moisturizing lotions or ointments can help soften the skin, and a cold-water room humidifier can keep your skin moist. […] Reducing stress is critical, and some experts suggest biofeedback training to reduce pain and promote relaxation. […] Joining a scleroderma support group can also help.

• #43 Scleroderma: Causes, Symptoms, Treatments, and Prevention Guide

  https://www.apollo247.com/blog/article/scleroderma-definition-causes-symptoms-treatment-prevention

  Living with Scleroderma involves not only medical treatments but also adopting a healthy lifestyle to manage symptoms and improve overall well-being. […] Regular Exercise and Stretching […] Exercise and stretching can help maintain joint flexibility, muscle strength, and overall mobility. Low-impact activities like walking, swimming, and gentle yoga are often recommended. […] Proper Skin Care and Protection from UV Rays […] Since scleroderma can make the skin more sensitive, it’s crucial to protect it from excessive sun exposure. Use sunscreen with a high SPF, wear protective clothing, and avoid prolonged sun exposure to prevent skin damage. […] Quitting Smoking and Avoiding Second-hand Smoke […] Smoking can worsen the symptoms of scleroderma and increase the risk of vascular complications. Quitting smoking and avoiding second-hand smoke exposure are essential for managing the disease. […] Balanced Diet and Healthy Eating Habits […] A well-balanced diet can support overall health and help manage specific symptoms. […] Limit processed foods and high-fat foods as these can exacerbate symptoms and negatively affect overall health.

• #44 How can I prevent scleroderma? – HealthyWomen

  https://www.healthywomen.org/ask-expert/how-can-i-prevent-scleroderma

  No one really knows enough about scleroderma to know whether there is a way to prevent the disease or delay its onset. […] Although clear-cut guidance on prevention is lacking, there are measures you can take to prevent or lessen the symptoms if you have been diagnosed with scleroderma. […] Dental care is essential. […] Regular exercise or stretching can maintain joint flexibility and help keep your skin pliable. […] Other strategies include frequent massage of the skin and avoidance of detergent soaps, which dry the skin. […] Frequent use of bath oils and moisturizing lotions or ointments can help soften the skin, and a cold-water room humidifier can keep your skin moist. […] Reducing stress is critical, and some experts suggest biofeedback training to reduce pain and promote relaxation. […] Joining a scleroderma support group can also help.

• #45 Scleroderma: Causes, Symptoms, Treatments, and Prevention Guide

  https://www.apollo247.com/blog/article/scleroderma-definition-causes-symptoms-treatment-prevention

  Living with Scleroderma involves not only medical treatments but also adopting a healthy lifestyle to manage symptoms and improve overall well-being. […] Regular Exercise and Stretching […] Exercise and stretching can help maintain joint flexibility, muscle strength, and overall mobility. Low-impact activities like walking, swimming, and gentle yoga are often recommended. […] Proper Skin Care and Protection from UV Rays […] Since scleroderma can make the skin more sensitive, it’s crucial to protect it from excessive sun exposure. Use sunscreen with a high SPF, wear protective clothing, and avoid prolonged sun exposure to prevent skin damage. […] Quitting Smoking and Avoiding Second-hand Smoke […] Smoking can worsen the symptoms of scleroderma and increase the risk of vascular complications. Quitting smoking and avoiding second-hand smoke exposure are essential for managing the disease. […] Balanced Diet and Healthy Eating Habits […] A well-balanced diet can support overall health and help manage specific symptoms. […] Limit processed foods and high-fat foods as these can exacerbate symptoms and negatively affect overall health.

• #46 Scleroderma: Causes, Symptoms, Treatments, and Prevention Guide

  https://www.apollo247.com/blog/article/scleroderma-definition-causes-symptoms-treatment-prevention

  Living with Scleroderma involves not only medical treatments but also adopting a healthy lifestyle to manage symptoms and improve overall well-being. […] Regular Exercise and Stretching […] Exercise and stretching can help maintain joint flexibility, muscle strength, and overall mobility. Low-impact activities like walking, swimming, and gentle yoga are often recommended. […] Proper Skin Care and Protection from UV Rays […] Since scleroderma can make the skin more sensitive, it’s crucial to protect it from excessive sun exposure. Use sunscreen with a high SPF, wear protective clothing, and avoid prolonged sun exposure to prevent skin damage. […] Quitting Smoking and Avoiding Second-hand Smoke […] Smoking can worsen the symptoms of scleroderma and increase the risk of vascular complications. Quitting smoking and avoiding second-hand smoke exposure are essential for managing the disease. […] Balanced Diet and Healthy Eating Habits […] A well-balanced diet can support overall health and help manage specific symptoms. […] Limit processed foods and high-fat foods as these can exacerbate symptoms and negatively affect overall health.

• #47 Scleroderma: Causes, Symptoms, Treatments, and Prevention Guide

  https://www.apollo247.com/blog/article/scleroderma-definition-causes-symptoms-treatment-prevention

  Living with Scleroderma involves not only medical treatments but also adopting a healthy lifestyle to manage symptoms and improve overall well-being. […] Regular Exercise and Stretching […] Exercise and stretching can help maintain joint flexibility, muscle strength, and overall mobility. Low-impact activities like walking, swimming, and gentle yoga are often recommended. […] Proper Skin Care and Protection from UV Rays […] Since scleroderma can make the skin more sensitive, it’s crucial to protect it from excessive sun exposure. Use sunscreen with a high SPF, wear protective clothing, and avoid prolonged sun exposure to prevent skin damage. […] Quitting Smoking and Avoiding Second-hand Smoke […] Smoking can worsen the symptoms of scleroderma and increase the risk of vascular complications. Quitting smoking and avoiding second-hand smoke exposure are essential for managing the disease. […] Balanced Diet and Healthy Eating Habits […] A well-balanced diet can support overall health and help manage specific symptoms. […] Limit processed foods and high-fat foods as these can exacerbate symptoms and negatively affect overall health.

• #48 How can I prevent scleroderma? – HealthyWomen

  https://www.healthywomen.org/ask-expert/how-can-i-prevent-scleroderma

  No one really knows enough about scleroderma to know whether there is a way to prevent the disease or delay its onset. […] Although clear-cut guidance on prevention is lacking, there are measures you can take to prevent or lessen the symptoms if you have been diagnosed with scleroderma. […] Dental care is essential. […] Regular exercise or stretching can maintain joint flexibility and help keep your skin pliable. […] Other strategies include frequent massage of the skin and avoidance of detergent soaps, which dry the skin. […] Frequent use of bath oils and moisturizing lotions or ointments can help soften the skin, and a cold-water room humidifier can keep your skin moist. […] Reducing stress is critical, and some experts suggest biofeedback training to reduce pain and promote relaxation. […] Joining a scleroderma support group can also help.

• #49 Scleroderma – symptoms, causes and treatment | healthdirect

  https://www.healthdirect.gov.au/scleroderma

  Can scleroderma be prevented? […] It’s currently not possible to prevent scleroderma. […] You can help prevent complications from Raynaud phenomenon by: stopping smoking, avoiding getting cold, reducing stress.

• #50 How can I prevent scleroderma? – HealthyWomen

  https://www.healthywomen.org/ask-expert/how-can-i-prevent-scleroderma

  No one really knows enough about scleroderma to know whether there is a way to prevent the disease or delay its onset. […] Although clear-cut guidance on prevention is lacking, there are measures you can take to prevent or lessen the symptoms if you have been diagnosed with scleroderma. […] Dental care is essential. […] Regular exercise or stretching can maintain joint flexibility and help keep your skin pliable. […] Other strategies include frequent massage of the skin and avoidance of detergent soaps, which dry the skin. […] Frequent use of bath oils and moisturizing lotions or ointments can help soften the skin, and a cold-water room humidifier can keep your skin moist. […] Reducing stress is critical, and some experts suggest biofeedback training to reduce pain and promote relaxation. […] Joining a scleroderma support group can also help.

• #51 How can I prevent scleroderma? – HealthyWomen

  https://www.healthywomen.org/ask-expert/how-can-i-prevent-scleroderma

  No one really knows enough about scleroderma to know whether there is a way to prevent the disease or delay its onset. […] Although clear-cut guidance on prevention is lacking, there are measures you can take to prevent or lessen the symptoms if you have been diagnosed with scleroderma. […] Dental care is essential. […] Regular exercise or stretching can maintain joint flexibility and help keep your skin pliable. […] Other strategies include frequent massage of the skin and avoidance of detergent soaps, which dry the skin. […] Frequent use of bath oils and moisturizing lotions or ointments can help soften the skin, and a cold-water room humidifier can keep your skin moist. […] Reducing stress is critical, and some experts suggest biofeedback training to reduce pain and promote relaxation. […] Joining a scleroderma support group can also help.

• #52 How can I prevent scleroderma? – HealthyWomen

  https://www.healthywomen.org/ask-expert/how-can-i-prevent-scleroderma

  No one really knows enough about scleroderma to know whether there is a way to prevent the disease or delay its onset. […] Although clear-cut guidance on prevention is lacking, there are measures you can take to prevent or lessen the symptoms if you have been diagnosed with scleroderma. […] Dental care is essential. […] Regular exercise or stretching can maintain joint flexibility and help keep your skin pliable. […] Other strategies include frequent massage of the skin and avoidance of detergent soaps, which dry the skin. […] Frequent use of bath oils and moisturizing lotions or ointments can help soften the skin, and a cold-water room humidifier can keep your skin moist. […] Reducing stress is critical, and some experts suggest biofeedback training to reduce pain and promote relaxation. […] Joining a scleroderma support group can also help.

• #53 Systemic Sclerosis Treatment: Experts Provide a New Framework – Rheumatology Advisor

  https://www.rheumatologyadvisor.com/home/topics/scleroderma/experts-provide-new-framework-for-systemic-sclerosis-treatment/

  Data show that delayed treatment is common in SSc. Identification of these underlying signs offers an opportunity for improved therapeutic outcomes with earlier diagnosis, whereby many SSc-related vascular, cardiac, gastrointestinal, nutritional, and musculoskeletal complications can be treated and even prevented. […] Preventing death and permanent disability in systemic sclerosis is accomplished with early and appropriate treatment, the authors wrote, noting that a major obstacle is posed by the challenges to positively differentiating between earlier states of active progressive disease and the later transformation to fibrotic damage. […] The new framework recommends a comprehensive and interactional approach between providers of multiple disciplines in order to optimally manage the disease over time. Sharing care between recognised SSc centers and local cardiology/pulmonary/rheumatology/gastroenterology colleagues may prevent complications and poor outcomes, while providing support to local specialists.

• #54 Systemic Sclerosis Treatment: Experts Provide a New Framework – Rheumatology Advisor

  https://www.rheumatologyadvisor.com/home/topics/scleroderma/experts-provide-new-framework-for-systemic-sclerosis-treatment/

  Data show that delayed treatment is common in SSc. Identification of these underlying signs offers an opportunity for improved therapeutic outcomes with earlier diagnosis, whereby many SSc-related vascular, cardiac, gastrointestinal, nutritional, and musculoskeletal complications can be treated and even prevented. […] Preventing death and permanent disability in systemic sclerosis is accomplished with early and appropriate treatment, the authors wrote, noting that a major obstacle is posed by the challenges to positively differentiating between earlier states of active progressive disease and the later transformation to fibrotic damage. […] The new framework recommends a comprehensive and interactional approach between providers of multiple disciplines in order to optimally manage the disease over time. Sharing care between recognised SSc centers and local cardiology/pulmonary/rheumatology/gastroenterology colleagues may prevent complications and poor outcomes, while providing support to local specialists.

• #55 Scleroderma: Symptoms, Causes & Treatment Options

  https://my.clevelandclinic.org/health/diseases/scleroderma

  Because experts dont know what causes it, theres no way to prevent scleroderma. […] You should expect to manage scleroderma and its symptoms for the rest of your life. Even though theres no cure, most people find treatments and lifestyle tweaks to minimize how much their symptoms impact their day-to-day lives.

• #56 Scleroderma

  https://www.printo.it/pediatric-rheumatology/IE/info/5/Scleroderma

  1.5 Can it be prevented? There is no known prevention for this condition. This means that you as a parent or a patient could not have done anything to prevent the disease. […] 3.1 How long will the disease last? The progression of localised scleroderma is usually limited to a few years. The skin hardening often stops after a few years from the start of the disease. Sometimes it can take up to 5 6 years and some patches may even become more visible after the inflammatory process is over due to colour changes, or the disease may appear worse due to unequal growth between affected and unaffected parts of the body. Systemic sclerosis is a long-term disease that can last for many years. However, early and appropriate treatment can lessen the impact of the disease. […] 3.2 Is it possible to recover completely? Children with localised scleroderma may recover completely. After some point even the hard skin may soften and only hyperpigmented areas may persist. Recovery from systemic sclerosis is much less probable, but significant improvements and stabilisation of disease may be achieved, allowing a good quality of life.

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