Materiały źródłowe

• #1 Lipoma Pathology – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK482343/

  Lipomas are defined as a common subcutaneous tumor composed of adipose (fat) cells, often encapsulated by a thin layer of fibrous tissue. […] The prevalence of lipomas has been cited as affecting 1% of the population, while its incidence, which is possibly underreported, is 2.1 per 1000 individuals per year. […] If lipomas are not painful and harmless, there is no need for removal.

• #2 Lipoma and Atypical Lipomatous Tumors – OrthoInfo – AAOS

  https://orthoinfo.aaos.org/en/diseases–conditions/lipoma

  A lipoma is a benign (noncancerous) tumor made up of fat tissue. It is the most common soft tissue tumor found in adults. […] They occur slightly more often in men than in women. […] They most often appear between the ages of 40 and 60 years, although they can occur at any age. […] They do not typically change after they form, and have very little potential for becoming cancerous. […] However, if a lipoma is painful or continues to grow larger, it can be removed with a surgical procedure. […] Atypical lipomatous tumors (ALT) are fatty tumors that can increase in size over time. […] ALT is a relatively new term for large atypical fatty tumors in the extremities (arms or legs). […] An ALT can be surgically removed, similar to a standard lipoma. […] The cause of lipomas is not completely understood.

• #3 Lipoma

  https://mobile.fpnotebook.com/Derm/Hyperplasia/Lpm.htm

  Most common subcutaneous soft-tissue tumor (accounts for 50% of Soft Tissue Masses) […] Prevalence: 1% […] Age of onset usually 40 to 60 years […] Gender prediposition: Single Lipomas more common in women […] Multiple Lipomas (Lipomatosis) more common in men.

• #4 Lipoma – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507906/

  Lipomas have a slightly higher incidence in males compared to females. […] Although they can occur at any age, they are often noted between the fourth to sixth decades of life. […] Despite being one of the most common neoplasms in humans, the incidence and prevalence of lipomas have not been reported in the literature.

• #5 Lipoma Pathology – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK482343/

  Lipomas are defined as a common subcutaneous tumor composed of adipose (fat) cells, often encapsulated by a thin layer of fibrous tissue. […] The prevalence of lipomas has been cited as affecting 1% of the population, while its incidence, which is possibly underreported, is 2.1 per 1000 individuals per year. […] If lipomas are not painful and harmless, there is no need for removal.

• #6 Lipoma | 5-Minute Clinical Consult

  https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/116841/all/Lipoma?q=Ankle+pain

  Lipomas can occur at any age but most commonly occur in middle-aged adults, typically in the 40- to 60-year-old age group, and more likely in men. […] Conventional lipomas and most variants are rare in children; however, lipoblastoma and diffuse lipomatosis typically present in children 3 years of age. […] No clear gender predilection in conventional lipomas and most variants. […] Approximately 5% of patients have multiple lipomas. […] Has been reported as 2.1/1,000 individuals per year; however, incidence is difficult to accurately estimate. […] Has been reported as present in ~1% the population; however, as with incidence, prevalence is difficult to accurately estimate and is most likely underestimated.

• #7 Cutaneous Lipomas: Background, Pathophysiology, Epidemiology

  https://emedicine.medscape.com/article/1057855-overview

  In one study of a Scandinavian population, 43% of benign mesenchymal tumors were lipomas. Overall, the incidence of a lipoma occurs in 1 in 1000 people. […] Solitary lipomas are seen predominately in women. Multiple lipomas occur more frequently in men. […] Lipomas can occur at any age; however, they usually arise in early adulthood. Rarely, they can occur in childhood or infancy.

• #8 Lipoma: Symptoms and Treatment | Doctor

  https://patient.info/doctor/lipoma-pro

  Lipomas may be seen in all age groups, but usually first appear between 40 and 60 years of age. […] Solitary lipomas are more common in women. Multiples – referred to as lipomatosis – are more common in men. […] They have an estimated annual incidence of one per 1,000 of the population. […] Congenital lipomas have been observed in children.

• #9 Lipoma epidemiology and demographics – wikidoc

  https://www.wikidoc.org/index.php/Lipoma_epidemiology_and_demographics

  Lipoma incidence is 100 per 100,000 individuals worldwide annually. […] Lipoma tend to affect middle age individuals, especially those of 40 to 60 years of age. […] Lipoma affects men at a greater extent than women. […] Lipoma develops in all races equally.

• #10 Lipoma overview – wikidoc

  https://www.wikidoc.org/index.php/Lipoma_overview

  Lipoma incidence is 100 per 100,000 individuals worldwide annually. […] Lipoma tend to affect middle age individuals, especially those of 40 to 60 years of age. […] It affects men at a greater extent than women.

• #11 Cutaneous Lipomas: Background, Pathophysiology, Epidemiology

  https://emedicine.medscape.com/article/1057855-overview

  In one study of a Scandinavian population, 43% of benign mesenchymal tumors were lipomas. Overall, the incidence of a lipoma occurs in 1 in 1000 people. […] Solitary lipomas are seen predominately in women. Multiple lipomas occur more frequently in men. […] Lipomas can occur at any age; however, they usually arise in early adulthood. Rarely, they can occur in childhood or infancy.

• #12 Lipoma Pathology – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK482343/

  Lipomas are defined as a common subcutaneous tumor composed of adipose (fat) cells, often encapsulated by a thin layer of fibrous tissue. […] The prevalence of lipomas has been cited as affecting 1% of the population, while its incidence, which is possibly underreported, is 2.1 per 1000 individuals per year. […] If lipomas are not painful and harmless, there is no need for removal.

• #13 Lipomas: Practice Essentials, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/191233-overview

  Lipomas occur in 1% of the population. Most of these are small subcutaneous tumors that are removed for cosmetic reasons. […] In the intestine, lipomas constitute 16% of benign, small neoplasms; this percentage is lower than that of leiomyomas (18%) and higher than that of adenomas (14%).

• #14 Lipoma – Wikipedia

  https://en.wikipedia.org/wiki/Lipoma

  Around 2% of the general population has a lipoma. […] These tumors can occur at any age, but are most common in middle age, often appearing in people from 40 to 60 years old. […] Cutaneous lipomas are rare in children, but these tumors can occur as part of the inherited disease Bannayan-Zonana syndrome.

• #15 Lipomas are benign masses caused by overgrowth of fat cells | UCLA Health

  https://www.uclahealth.org/news/article/lipomas-are-benign-masses-caused-by-overgrowth-of-fat-cells

  Lipomas are typically found just below the surface of the skin, often on the trunk, neck, limbs or forehead. […] It is estimated that 1% to 2% of people will develop a lipoma in their lifetime. […] Lipomas occur slightly more often in men than in women, and although they can appear at any age, they become more common in adults between the ages of 40 and 70. […] While its possible for a lipoma to become malignant, this is quite rare. […] It is rare for a lipoma that has been surgically removed to recur.

• #16 Soft Tissues: Lipoma / benign lipomatous tumors

  https://atlasgeneticsoncology.org/solid-tumor/5050/soft-tissues-lipoma-benign-lipomatous-tumors

  lipomas are benign adipose tissue tumors with many subtypes, constituting one-third of all soft tissue tumors […] Epidemiology: the incidence of lipomas is about one in 1000 inhabitants per year, but is probably underestimated since many lesions cause few problems; they occur most frequently between 30 and 70 years of age, with a peak incidence between 40 and 60 years.

• #17 Lipoma | 5-Minute Clinical Consult

  https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/116841/all/Lipoma?q=Ankle+pain

  Lipomas can occur at any age but most commonly occur in middle-aged adults, typically in the 40- to 60-year-old age group, and more likely in men. […] Conventional lipomas and most variants are rare in children; however, lipoblastoma and diffuse lipomatosis typically present in children 3 years of age. […] No clear gender predilection in conventional lipomas and most variants. […] Approximately 5% of patients have multiple lipomas. […] Has been reported as 2.1/1,000 individuals per year; however, incidence is difficult to accurately estimate. […] Has been reported as present in ~1% the population; however, as with incidence, prevalence is difficult to accurately estimate and is most likely underestimated.

• #18 Lipoma – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507906/

  Lipomas have a slightly higher incidence in males compared to females. […] Although they can occur at any age, they are often noted between the fourth to sixth decades of life. […] Despite being one of the most common neoplasms in humans, the incidence and prevalence of lipomas have not been reported in the literature.

• #19 Lipoma and Atypical Lipomatous Tumors – OrthoInfo – AAOS

  https://orthoinfo.aaos.org/en/diseases–conditions/lipoma

  A lipoma is a benign (noncancerous) tumor made up of fat tissue. It is the most common soft tissue tumor found in adults. […] They occur slightly more often in men than in women. […] They most often appear between the ages of 40 and 60 years, although they can occur at any age. […] They do not typically change after they form, and have very little potential for becoming cancerous. […] However, if a lipoma is painful or continues to grow larger, it can be removed with a surgical procedure. […] Atypical lipomatous tumors (ALT) are fatty tumors that can increase in size over time. […] ALT is a relatively new term for large atypical fatty tumors in the extremities (arms or legs). […] An ALT can be surgically removed, similar to a standard lipoma. […] The cause of lipomas is not completely understood.

• #20 Lipoma: Symptoms and Treatment | Doctor

  https://patient.info/doctor/lipoma-pro

  Lipomas may be seen in all age groups, but usually first appear between 40 and 60 years of age. […] Solitary lipomas are more common in women. Multiples – referred to as lipomatosis – are more common in men. […] They have an estimated annual incidence of one per 1,000 of the population. […] Congenital lipomas have been observed in children.

• #21

  https://www.orthobullets.com/pathology/8067/lipomas

  Lipomas are common benign tumors of mature fat which may be subcutaneous, extramuscular, or intramuscular. […] The condition is typically seen in patients 40-60 years of age who present with a stable, mobile, and painless mass. […] Epidemiology: slightly more common in men. […] affects predominantly patients between 40-60 years old. […] develops in sedentary individuals. […] Superficial/subcutaneous location is common; superficial lesions are common in the upper back, thighs, buttocks, shoulders and arms. […] ~5-10% of patients with a known superficial lipoma, will have multiple lesions.

• #22 Lipoma – UtahDERM Diagnoses

  https://utahderm.med.utah.edu/diagnoses/lipoma/

  Lipomas can be seen at any age, but are mostly commonly seen between the fourth to sixth decades of life. […] There is an increased incidence in patients with obesity, diabetes, or elevated cholesterol.

• #23 From pathogenesis to treatment, a systemic review of cardiac lipoma | Journal of Cardiothoracic Surgery | Full Text

  https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-020-01379-6

  True lipomas with fibrous encapsulation occurring in heart and pericardium are very rare. The reported incidence of primary heart tumors in the autopsy series is between 0.20.4%, of which cardiac lipomas account for 8.4%. […] By searching PubMed, we found that more than 300 cases of true cardiac lipomas have been reported. Two hundred fifty-five cases of cardiac lipoma with available details were included and reviewed. […] Among the included cases, no difference in the distribution of cardiac lipoma between genders (126 female, 120 male, in 9 cases gender is not available) was shown. Cardiac lipomas may occur at any age of life from the fetal period to the elderly in their 80s. Most cardiac lipomas occur in the 40-70 age group (153/255, 60.0%). […] The different sites of origin of lipomas within the heart have not been described in detail. The commonly described locations of origin are: 25% from the subpericardium, 25% from the myocardium and 50% from the subendocardium.

• #24 Lipoma – Wikipedia

  https://en.wikipedia.org/wiki/Lipoma

  Around 2% of the general population has a lipoma. […] These tumors can occur at any age, but are most common in middle age, often appearing in people from 40 to 60 years old. […] Cutaneous lipomas are rare in children, but these tumors can occur as part of the inherited disease Bannayan-Zonana syndrome.

• #25 Lipoma | 5-Minute Clinical Consult

  https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/116841/all/Lipoma?q=Ankle+pain

  Lipomas can occur at any age but most commonly occur in middle-aged adults, typically in the 40- to 60-year-old age group, and more likely in men. […] Conventional lipomas and most variants are rare in children; however, lipoblastoma and diffuse lipomatosis typically present in children 3 years of age. […] No clear gender predilection in conventional lipomas and most variants. […] Approximately 5% of patients have multiple lipomas. […] Has been reported as 2.1/1,000 individuals per year; however, incidence is difficult to accurately estimate. […] Has been reported as present in ~1% the population; however, as with incidence, prevalence is difficult to accurately estimate and is most likely underestimated.

• #26 Lipoma | 5-Minute Clinical Consult

  https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/116841/all/Lipoma?q=Ankle+pain

  Lipomas can occur at any age but most commonly occur in middle-aged adults, typically in the 40- to 60-year-old age group, and more likely in men. […] Conventional lipomas and most variants are rare in children; however, lipoblastoma and diffuse lipomatosis typically present in children 3 years of age. […] No clear gender predilection in conventional lipomas and most variants. […] Approximately 5% of patients have multiple lipomas. […] Has been reported as 2.1/1,000 individuals per year; however, incidence is difficult to accurately estimate. […] Has been reported as present in ~1% the population; however, as with incidence, prevalence is difficult to accurately estimate and is most likely underestimated.

• #27 Epidemiology of Spinal Lipoma in Children – ISPN Guide

  https://ispn.guide/congenital-disorders-of-the-nervous-system-in-children/spinal-lipoma-in-children-homepage/epidemiology-of-spinal-lipoma-in-children/

  0.06% to 0.25% in general population: The incidence of spinal lipomas in international medical literature shows considerable variation due to population demographics, lipoma definitions, and diagnostic criteria. Nonetheless, consensus within the medical community suggests that spinal lipomas are infrequent, with incidence rates ranging from 0.06% to 0.25% in the general population. […] Up to 1.5% in children: Among children, the incidence may be as high as 1.5%. […] Female 1.6 times that of male: Most series report a female predominance, with a female-to-male ratio of 1.6 to 1. This differs significantly from the gender distribution in meningomyelocele, which displays an equal ratio, and for spina bifida occulta in general, where a higher male predominance is reported. […] Unknown: Accurate data on the global incidence variations of spinal lipomas is sparse.

• #28 Lipoma – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507906/

  Lipomas have a slightly higher incidence in males compared to females. […] Although they can occur at any age, they are often noted between the fourth to sixth decades of life. […] Despite being one of the most common neoplasms in humans, the incidence and prevalence of lipomas have not been reported in the literature.

• #29 Lipoma and Atypical Lipomatous Tumors – OrthoInfo – AAOS

  https://orthoinfo.aaos.org/en/diseases–conditions/lipoma

  A lipoma is a benign (noncancerous) tumor made up of fat tissue. It is the most common soft tissue tumor found in adults. […] They occur slightly more often in men than in women. […] They most often appear between the ages of 40 and 60 years, although they can occur at any age. […] They do not typically change after they form, and have very little potential for becoming cancerous. […] However, if a lipoma is painful or continues to grow larger, it can be removed with a surgical procedure. […] Atypical lipomatous tumors (ALT) are fatty tumors that can increase in size over time. […] ALT is a relatively new term for large atypical fatty tumors in the extremities (arms or legs). […] An ALT can be surgically removed, similar to a standard lipoma. […] The cause of lipomas is not completely understood.

• #30 Lipomas are benign masses caused by overgrowth of fat cells | UCLA Health

  https://www.uclahealth.org/news/article/lipomas-are-benign-masses-caused-by-overgrowth-of-fat-cells

  Lipomas are typically found just below the surface of the skin, often on the trunk, neck, limbs or forehead. […] It is estimated that 1% to 2% of people will develop a lipoma in their lifetime. […] Lipomas occur slightly more often in men than in women, and although they can appear at any age, they become more common in adults between the ages of 40 and 70. […] While its possible for a lipoma to become malignant, this is quite rare. […] It is rare for a lipoma that has been surgically removed to recur.

• #31

  https://www.orthobullets.com/pathology/8067/lipomas

  Lipomas are common benign tumors of mature fat which may be subcutaneous, extramuscular, or intramuscular. […] The condition is typically seen in patients 40-60 years of age who present with a stable, mobile, and painless mass. […] Epidemiology: slightly more common in men. […] affects predominantly patients between 40-60 years old. […] develops in sedentary individuals. […] Superficial/subcutaneous location is common; superficial lesions are common in the upper back, thighs, buttocks, shoulders and arms. […] ~5-10% of patients with a known superficial lipoma, will have multiple lesions.

• #32 Lipoma | 5-Minute Clinical Consult

  https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/116841/all/Lipoma?q=Ankle+pain

  Lipomas can occur at any age but most commonly occur in middle-aged adults, typically in the 40- to 60-year-old age group, and more likely in men. […] Conventional lipomas and most variants are rare in children; however, lipoblastoma and diffuse lipomatosis typically present in children 3 years of age. […] No clear gender predilection in conventional lipomas and most variants. […] Approximately 5% of patients have multiple lipomas. […] Has been reported as 2.1/1,000 individuals per year; however, incidence is difficult to accurately estimate. […] Has been reported as present in ~1% the population; however, as with incidence, prevalence is difficult to accurately estimate and is most likely underestimated.

• #33 What Is a Lipoma? – Consensus: AI Search Engine for Research

  https://consensus.app/home/blog/what-is-a-lipoma/

  Lipomas can occur at any age but are most commonly found in middle-aged adults. They are equally prevalent in men and women. […] While the exact cause of lipomas is not well understood, genetic factors may play a role, as they often run in families.

• #34 Lipoma (fatty lumps)

  https://dermnetnz.org/topics/lipoma

  While lipomas typically affect patients between 40 and 60 years of age, they can occur at any age and are more common in patients with hyperlipidaemia, type 2 diabetes mellitus, and obesity. Both sexes are equally affected. […] Local recurrence is rare with excision and malignant transformation is exceedingly rare.

• #35 Cutaneous Lipomas: Background, Pathophysiology, Epidemiology

  https://emedicine.medscape.com/article/1057855-overview

  In one study of a Scandinavian population, 43% of benign mesenchymal tumors were lipomas. Overall, the incidence of a lipoma occurs in 1 in 1000 people. […] Solitary lipomas are seen predominately in women. Multiple lipomas occur more frequently in men. […] Lipomas can occur at any age; however, they usually arise in early adulthood. Rarely, they can occur in childhood or infancy.

• #36 Lipoma: Symptoms and Treatment | Doctor

  https://patient.info/doctor/lipoma-pro

  Lipomas may be seen in all age groups, but usually first appear between 40 and 60 years of age. […] Solitary lipomas are more common in women. Multiples – referred to as lipomatosis – are more common in men. […] They have an estimated annual incidence of one per 1,000 of the population. […] Congenital lipomas have been observed in children.

• #37 Healthy Street – LIPOMA – EPIDEMIOLOGY, SYMPTOMS &…FacebookShared with Public

  https://www.facebook.com/healthystreet/posts/lipoma-epidemiology-symptoms-treatmentlipoma-is-a-benign-tumor-composed-of-the-b/1079568048862771/

  LIPOMA – EPIDEMIOLOGY, SYMPTOMS & TREATMENT […] Lipoma is a benign tumor composed of the body fat or the adipose tissues which affects almost one in 1000 people. […] Lipomas are common and about one in every 1000 people suffer from Lipoma. […] People of all age groups can be affected by Lipomas, though the most common age group is 40 to 60 years. […] Solitary Lipomas are comparatively more common in women, however multiple lipomas occur more commonly and frequently in men.

• #38 Lipoma

  https://mobile.fpnotebook.com/Derm/Hyperplasia/Lpm.htm

  Most common subcutaneous soft-tissue tumor (accounts for 50% of Soft Tissue Masses) […] Prevalence: 1% […] Age of onset usually 40 to 60 years […] Gender prediposition: Single Lipomas more common in women […] Multiple Lipomas (Lipomatosis) more common in men.

• #39 Epidemiology of Spinal Lipoma in Children – ISPN Guide

  https://ispn.guide/congenital-disorders-of-the-nervous-system-in-children/spinal-lipoma-in-children-homepage/epidemiology-of-spinal-lipoma-in-children/

  0.06% to 0.25% in general population: The incidence of spinal lipomas in international medical literature shows considerable variation due to population demographics, lipoma definitions, and diagnostic criteria. Nonetheless, consensus within the medical community suggests that spinal lipomas are infrequent, with incidence rates ranging from 0.06% to 0.25% in the general population. […] Up to 1.5% in children: Among children, the incidence may be as high as 1.5%. […] Female 1.6 times that of male: Most series report a female predominance, with a female-to-male ratio of 1.6 to 1. This differs significantly from the gender distribution in meningomyelocele, which displays an equal ratio, and for spina bifida occulta in general, where a higher male predominance is reported. […] Unknown: Accurate data on the global incidence variations of spinal lipomas is sparse.

• #40 From pathogenesis to treatment, a systemic review of cardiac lipoma | Journal of Cardiothoracic Surgery | Full Text

  https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-020-01379-6

  True lipomas with fibrous encapsulation occurring in heart and pericardium are very rare. The reported incidence of primary heart tumors in the autopsy series is between 0.20.4%, of which cardiac lipomas account for 8.4%. […] By searching PubMed, we found that more than 300 cases of true cardiac lipomas have been reported. Two hundred fifty-five cases of cardiac lipoma with available details were included and reviewed. […] Among the included cases, no difference in the distribution of cardiac lipoma between genders (126 female, 120 male, in 9 cases gender is not available) was shown. Cardiac lipomas may occur at any age of life from the fetal period to the elderly in their 80s. Most cardiac lipomas occur in the 40-70 age group (153/255, 60.0%). […] The different sites of origin of lipomas within the heart have not been described in detail. The commonly described locations of origin are: 25% from the subpericardium, 25% from the myocardium and 50% from the subendocardium.

• #41 Intramuscular lipoma | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/intramuscular-lipoma?lang=us

  Intramuscular lipomas account for about 1% of all lipomas and occur in all age groups with most occurring between the 5th to 7th decades of life. There seems to be a female predominance 1. […] Intramuscular lipomas are deep-seated lipomas located within a muscle.

• #42 Lipoma | 5-Minute Clinical Consult

  https://im.unboundmedicine.com/medicine/view/5-Minute-Clinical-Consult/116841/all/Lipoma?q=Ankle+pain

  Lipomas can occur at any age but most commonly occur in middle-aged adults, typically in the 40- to 60-year-old age group, and more likely in men. […] Conventional lipomas and most variants are rare in children; however, lipoblastoma and diffuse lipomatosis typically present in children 3 years of age. […] No clear gender predilection in conventional lipomas and most variants. […] Approximately 5% of patients have multiple lipomas. […] Has been reported as 2.1/1,000 individuals per year; however, incidence is difficult to accurately estimate. […] Has been reported as present in ~1% the population; however, as with incidence, prevalence is difficult to accurately estimate and is most likely underestimated.

• #43

  https://www.orthobullets.com/pathology/8067/lipomas

  Lipomas are common benign tumors of mature fat which may be subcutaneous, extramuscular, or intramuscular. […] The condition is typically seen in patients 40-60 years of age who present with a stable, mobile, and painless mass. […] Epidemiology: slightly more common in men. […] affects predominantly patients between 40-60 years old. […] develops in sedentary individuals. […] Superficial/subcutaneous location is common; superficial lesions are common in the upper back, thighs, buttocks, shoulders and arms. […] ~5-10% of patients with a known superficial lipoma, will have multiple lesions.

• #44 Lipoma | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/lipoma?lang=us

  Lipomas are benign tumors composed of mature adipocytes. They are the most common soft tissue tumor, seen in ~2% of the population. […] Patients typically present in adulthood (5th-7th decades). […] In some cases, multiple lipomas are associated with syndromes and other diseases, including: Bannayan-Zonana syndrome, Cowden syndrome, Fröhlich syndrome, Proteus syndrome, Dercum disease, Madelung disease, familial multiple lipomatosis, and obesity.

• #45 Is A Lipoma Serious?: Ali Hendi, MD: Skin Cancer Specialists

  https://www.mohssurgerymd.com/blog/is-a-lipoma-serious

  About 1 in every 1,000 people has a lipoma. Lipomas are slow-growing masses of fatty tissue, and they aren’t cancerous or harmful to your health. […] Although the exact cause isn’t known, lipomas tend to run in families. So, if one of your relatives has a lipoma, you may get one, too. Having multiple lipomas, while less common, may stem from an underlying condition, such as Dercums disease, Gardner syndrome, or Madelungs disease.

• #46 Lipoma | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/lipoma?lang=us

  Lipomas are benign tumors composed of mature adipocytes. They are the most common soft tissue tumor, seen in ~2% of the population. […] Patients typically present in adulthood (5th-7th decades). […] In some cases, multiple lipomas are associated with syndromes and other diseases, including: Bannayan-Zonana syndrome, Cowden syndrome, Fröhlich syndrome, Proteus syndrome, Dercum disease, Madelung disease, familial multiple lipomatosis, and obesity.

• #47 Lipoma and Atypical Lipomatous Tumors – OrthoInfo – AAOS

  https://orthoinfo.aaos.org/en/diseases–conditions/lipoma

  A lipoma is a benign (noncancerous) tumor made up of fat tissue. It is the most common soft tissue tumor found in adults. […] They occur slightly more often in men than in women. […] They most often appear between the ages of 40 and 60 years, although they can occur at any age. […] They do not typically change after they form, and have very little potential for becoming cancerous. […] However, if a lipoma is painful or continues to grow larger, it can be removed with a surgical procedure. […] Atypical lipomatous tumors (ALT) are fatty tumors that can increase in size over time. […] ALT is a relatively new term for large atypical fatty tumors in the extremities (arms or legs). […] An ALT can be surgically removed, similar to a standard lipoma. […] The cause of lipomas is not completely understood.

• #48 Lipoma: What Is It, Causes, Symptoms, Types, Treatment

  https://my.clevelandclinic.org/health/diseases/15008-lipomas

  Lipomas are very common. About 1 of every 1,000 people has a lipoma. Lipomas appear most often between ages 40 and 60, but they can develop at any age. They can even be present at birth. Lipomas affect people of all genders, but they are slightly more common in women. […] Healthcare providers arent sure what causes lipomas to grow. They are inherited (passed down through families). Youre more likely to develop a lipoma if someone in your family has one. […] Lipomas (and many of the conditions that cause lipomas) are inherited. Since theyre passed down through families, it isnt possible to prevent them.

• #49 What Is a Lipoma? – Consensus: AI Search Engine for Research

  https://consensus.app/home/blog/what-is-a-lipoma/

  Lipomas can occur at any age but are most commonly found in middle-aged adults. They are equally prevalent in men and women. […] While the exact cause of lipomas is not well understood, genetic factors may play a role, as they often run in families.

• #50 Is A Lipoma Serious?: Ali Hendi, MD: Skin Cancer Specialists

  https://www.mohssurgerymd.com/blog/is-a-lipoma-serious

  About 1 in every 1,000 people has a lipoma. Lipomas are slow-growing masses of fatty tissue, and they aren’t cancerous or harmful to your health. […] Although the exact cause isn’t known, lipomas tend to run in families. So, if one of your relatives has a lipoma, you may get one, too. Having multiple lipomas, while less common, may stem from an underlying condition, such as Dercums disease, Gardner syndrome, or Madelungs disease.

• #51 Soft Tissues: Lipoma: Chondroid lipoma

  https://atlasgeneticsoncology.org/solid-tumor/5164/soft-tissues-lipoma-chondroid-lipoma

  Chondroid lipoma is an extremely rare benign adipose tissue tumour. Most tumours arise in adult women. […] Chondroid lipoma is characterized by a t(11;16)(q13;p13) chromosomal translocation that results in fusion of the C11orf95 (11q13) and MKL2 (16p13.3) genes.

• #52 Lipoma | Concise Medical Knowledge

  https://www.lecturio.com/concepts/lipoma/

  Lipoma is the most common benign soft tissue tumor in adults. […] Age: mostly adults, age 40 years; rare in children. […] Slightly higher incidence in men compared to women. […] Associated with hyperlipidemia, type 2 diabetes mellitus, and obesity. […] No ethnic preference. […] Multiple lipomas account for 5% of cases: often familial and often associated with genetic disorders.

• #53 Lipoma – UtahDERM Diagnoses

  https://utahderm.med.utah.edu/diagnoses/lipoma/

  Lipomas can be seen at any age, but are mostly commonly seen between the fourth to sixth decades of life. […] There is an increased incidence in patients with obesity, diabetes, or elevated cholesterol.

• #54 Lipoma (fatty lumps)

  https://dermnetnz.org/topics/lipoma

  While lipomas typically affect patients between 40 and 60 years of age, they can occur at any age and are more common in patients with hyperlipidaemia, type 2 diabetes mellitus, and obesity. Both sexes are equally affected. […] Local recurrence is rare with excision and malignant transformation is exceedingly rare.

• #55 Lipoma | Concise Medical Knowledge

  https://www.lecturio.com/concepts/lipoma/

  Lipoma is the most common benign soft tissue tumor in adults. […] Age: mostly adults, age 40 years; rare in children. […] Slightly higher incidence in men compared to women. […] Associated with hyperlipidemia, type 2 diabetes mellitus, and obesity. […] No ethnic preference. […] Multiple lipomas account for 5% of cases: often familial and often associated with genetic disorders.

• #56 Lipoma | Consultant360

  https://www.consultant360.com/articles/lipoma

  A lipoma is a benign tumor composed of collections of mature normal adipocytes arranged in lobules and enclosed by a well-defined, thin fibrous capsule. It is by far the most common mesenchymal neoplasm. Although lipomas have been reported in all organs, including the kidneys, liver, and lungs, they occur most frequently in the subcutaneous tissue. […] It is estimated that lipomas occur in 0.2% to 1% of the adult population. The peak incidence is between 40 and 60 years of age; however, young adults and children also can be affected. In general, solitary lipomas are more common in females, whereas multiple lipomas are more common in males. The condition is usually sporadic, although familial cases have also been reported. Lipomas are more common in individuals who are obese.

• #57 Lipoma and Atypical Lipomatous Tumors – OrthoInfo – AAOS

  https://orthoinfo.aaos.org/en/diseases–conditions/lipoma

  A lipoma is a benign (noncancerous) tumor made up of fat tissue. It is the most common soft tissue tumor found in adults. […] They occur slightly more often in men than in women. […] They most often appear between the ages of 40 and 60 years, although they can occur at any age. […] They do not typically change after they form, and have very little potential for becoming cancerous. […] However, if a lipoma is painful or continues to grow larger, it can be removed with a surgical procedure. […] Atypical lipomatous tumors (ALT) are fatty tumors that can increase in size over time. […] ALT is a relatively new term for large atypical fatty tumors in the extremities (arms or legs). […] An ALT can be surgically removed, similar to a standard lipoma. […] The cause of lipomas is not completely understood.

• #58

  https://www.orthobullets.com/pathology/8067/lipomas

  Lipomas are common benign tumors of mature fat which may be subcutaneous, extramuscular, or intramuscular. […] The condition is typically seen in patients 40-60 years of age who present with a stable, mobile, and painless mass. […] Epidemiology: slightly more common in men. […] affects predominantly patients between 40-60 years old. […] develops in sedentary individuals. […] Superficial/subcutaneous location is common; superficial lesions are common in the upper back, thighs, buttocks, shoulders and arms. […] ~5-10% of patients with a known superficial lipoma, will have multiple lesions.

• #59 Development of Lipoma among Residents Exposed to Glass Fiber Waste.

  https://www.e-epih.org/journal/view.php?number=184

  This study was conducted to determine the relationship between exposure to glass fiber waste from an insulator factory and the development of cluster of lipomas among local residents in suburb Incheon, Korea. […] Twelve(7.9%) had subcutaneous tumors among the 152 residents. Tumors were surgically excised from 3 of them and they were all lipomas, consisting of mature fat tissue. […] It is suggested that fibrous magnesium silicate, talc, a component of fiberglass waste, may be associated with the development of lipomas.

• #60 Lipomas of the nervous system | MedLink Neurology

  https://www.medlink.com/articles/lipomas-of-the-nervous-system

  Among patients undergoing spinal MRI for unrelated reasons, lipomas are incidentally discovered in about 4% of cases. […] Steroids are associated with development of extra-CNS lipomas. […] It is unclear if they are associated with an increased risk of CNS lipomas, although at least one case has suggested it.

• #61 Lipomas are benign masses caused by overgrowth of fat cells | UCLA Health

  https://www.uclahealth.org/news/article/lipomas-are-benign-masses-caused-by-overgrowth-of-fat-cells

  Lipomas are typically found just below the surface of the skin, often on the trunk, neck, limbs or forehead. […] It is estimated that 1% to 2% of people will develop a lipoma in their lifetime. […] Lipomas occur slightly more often in men than in women, and although they can appear at any age, they become more common in adults between the ages of 40 and 70. […] While its possible for a lipoma to become malignant, this is quite rare. […] It is rare for a lipoma that has been surgically removed to recur.

• #62 Lipoma | Consultant360

  https://www.consultant360.com/articles/lipoma

  A lipoma is a benign tumor composed of collections of mature normal adipocytes arranged in lobules and enclosed by a well-defined, thin fibrous capsule. It is by far the most common mesenchymal neoplasm. Although lipomas have been reported in all organs, including the kidneys, liver, and lungs, they occur most frequently in the subcutaneous tissue. […] It is estimated that lipomas occur in 0.2% to 1% of the adult population. The peak incidence is between 40 and 60 years of age; however, young adults and children also can be affected. In general, solitary lipomas are more common in females, whereas multiple lipomas are more common in males. The condition is usually sporadic, although familial cases have also been reported. Lipomas are more common in individuals who are obese.

• #63

  https://www.orthobullets.com/pathology/8067/lipomas

  Lipomas are common benign tumors of mature fat which may be subcutaneous, extramuscular, or intramuscular. […] The condition is typically seen in patients 40-60 years of age who present with a stable, mobile, and painless mass. […] Epidemiology: slightly more common in men. […] affects predominantly patients between 40-60 years old. […] develops in sedentary individuals. […] Superficial/subcutaneous location is common; superficial lesions are common in the upper back, thighs, buttocks, shoulders and arms. […] ~5-10% of patients with a known superficial lipoma, will have multiple lesions.

• #64 Online Turkish Journal of Health Sciences » Submission » Epidemiology of Subcutaneous Lipomas

  https://dergipark.org.tr/en/pub/otjhs/issue/48663/470122

  Lipoma is a slow growing, encapsulated, lobulated, fluctuant and painless tumour composed of fat cells. […] We aimed to review and evaluate the epidemiology of Subcutaneous Lipomas in this study. […] The prevalence of subcutaneous, non-visceral lipomas was more common in males as in our study, out of 126 patients, 78 (61.90%) patients were males and 48 (38.09%) patients were females. […] As a result in this study, lipomas were common, benign, slow growing, and generally asymptomatic tumours. […] They were more common in males and commonly occurred in the age group of 31-60 years. […] They commonly occurred in the head and neck and trunk region and were usually less than 5 cm in size.

• #65 Lipomas are benign masses caused by overgrowth of fat cells | UCLA Health

  https://www.uclahealth.org/news/article/lipomas-are-benign-masses-caused-by-overgrowth-of-fat-cells

  Lipomas are typically found just below the surface of the skin, often on the trunk, neck, limbs or forehead. […] It is estimated that 1% to 2% of people will develop a lipoma in their lifetime. […] Lipomas occur slightly more often in men than in women, and although they can appear at any age, they become more common in adults between the ages of 40 and 70. […] While its possible for a lipoma to become malignant, this is quite rare. […] It is rare for a lipoma that has been surgically removed to recur.

• #66 Lipoma Excision | Journal of Medical Insight

  https://jomi.com/article/268.18/lipoma-excision

  Lipomas occur in 1 in every 1,000 people and commonly grow on the upper back, shoulders, and abdomen. […] The prevalence of lipomas is roughly 1% of the population, making them one of the most common neoplasms seen in patients throughout the world. […] The incidence of lipomas is higher in males than in females; however, the difference is minor. […] Lipomas can develop at any age, but most commonly develop in middle adulthood. […] Fortunately, lipomas carry an excellent prognosis and do not transform into liposarcomas, which have an estimated incidence of less than 15 per 100,000 individuals. […] One should be suspicious if multiple lipomas are found during the physical exam, as it may be an early manifestation of certain diseases such as Cowden syndrome or Gardner syndrome, where lipomas as well as malignancies are both expressions of the underlying pathophysiology.

• #67 Lipoma | Consultant360

  https://www.consultant360.com/articles/lipoma

  A lipoma is a benign tumor composed of collections of mature normal adipocytes arranged in lobules and enclosed by a well-defined, thin fibrous capsule. It is by far the most common mesenchymal neoplasm. Although lipomas have been reported in all organs, including the kidneys, liver, and lungs, they occur most frequently in the subcutaneous tissue. […] It is estimated that lipomas occur in 0.2% to 1% of the adult population. The peak incidence is between 40 and 60 years of age; however, young adults and children also can be affected. In general, solitary lipomas are more common in females, whereas multiple lipomas are more common in males. The condition is usually sporadic, although familial cases have also been reported. Lipomas are more common in individuals who are obese.

• #68 Lipomas: Practice Essentials, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/191233-overview

  Lipomas occur in 1% of the population. Most of these are small subcutaneous tumors that are removed for cosmetic reasons. […] In the intestine, lipomas constitute 16% of benign, small neoplasms; this percentage is lower than that of leiomyomas (18%) and higher than that of adenomas (14%).

• #69

  https://journals.lww.com/ajg/fulltext/2021/10001/s3711_gastric_lipoma_in_a_patient_with_symptomatic.3715.aspx

  Gastric lipomas are very rare, accounting for 5% percent of all gastrointestinal lipomas, and 3% of all benign gastric tumors. […] Asymptomatic lipomas are managed expectantly, and do not require surveillance because malignant transformation is rare. […] In contrast, lipomas that are symptomatic or cause bleeding or obstruction, are usually surgically removed.

• #70

  https://journals.lww.com/ajg/fulltext/2018/10001/the_ball_in_socket_lesion__a_case_report_of_an.1648.aspx

  Lipomas of the gastrointestinal tract are the second most common benign lesions, with 70% occurring in the colon, particularly on the right side. Majority of lipomas are asymptomatic, have low risk of malignancy transformation and are discovered incidentally on routine colonoscopy. […] Our case adds to the literature available on colonic lipomas, however highlights an interesting case of a large asymptomatic extremely mobile lipoma originating from the ileocecal valve with the ability to extend into the terminal ileum in a ball-in-socket fashion. Reassuringly, the patient was asymptomatic, and thus watchful waiting was recommended without need for immediate resection. Our case also highlights the utility of stacked biopsies of benign appearing submucosal lesions to aid in the diagnosis and the importance of terminal ileum examination during colonoscopy.

• #71 Incidental finding of left ventricle lipoma in the setting of metastatic cancer: Is the decision of surveillance appropriate based on imaging alone? – JTCVS Techniques

  https://www.jtcvstechniques.org/article/S2666-2507(23)00217-1/fulltext

  Preliminary diagnosis of cardiac tumor using history and imaging characteristics can justify surveillance over immediate operative intervention in the appropriate setting. […] Incidence of these tumors in multiple autopsy series range from 0.2% to 0.4%. […] Cardiac lipomas account for 8.4% of these tumors and have been documented in all chambers of the heart and valve leaflets. […] The diagnosis of cardiac tumors is often based on patient history and imaging alone due to the difficulty of obtaining a biopsy. […] The imaging techniques that help delineate benign from malignant tumors include echocardiography, cardiac CT, and MRI. […] Definitive diagnosis cannot be made until surgery is performed and final pathology obtained. […] This raises a question: In an asymptomatic patient with metastatic cancer, is it safe to conclude whether or not a cardiac tumor is primary, secondary, malignant, benign, or even a thrombus based on imaging characteristics alone? […] History and imaging characteristics of a benign cardiac tumor in an asymptomatic patient provide satisfactory evidence to justify postponing treatment.

• #72 From pathogenesis to treatment, a systemic review of cardiac lipoma | Journal of Cardiothoracic Surgery | Full Text

  https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-020-01379-6

  True lipomas with fibrous encapsulation occurring in heart and pericardium are very rare. The reported incidence of primary heart tumors in the autopsy series is between 0.20.4%, of which cardiac lipomas account for 8.4%. […] By searching PubMed, we found that more than 300 cases of true cardiac lipomas have been reported. Two hundred fifty-five cases of cardiac lipoma with available details were included and reviewed. […] Among the included cases, no difference in the distribution of cardiac lipoma between genders (126 female, 120 male, in 9 cases gender is not available) was shown. Cardiac lipomas may occur at any age of life from the fetal period to the elderly in their 80s. Most cardiac lipomas occur in the 40-70 age group (153/255, 60.0%). […] The different sites of origin of lipomas within the heart have not been described in detail. The commonly described locations of origin are: 25% from the subpericardium, 25% from the myocardium and 50% from the subendocardium.

• #73 From pathogenesis to treatment, a systemic review of cardiac lipoma | Journal of Cardiothoracic Surgery | Full Text

  https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-020-01379-6

  The distribution within the heart suggests that around 48.7% lipomas arise from the subendomyocardium, 32.5% from subpericardium, 10.7% from myocardium and 4.4% from cardiac valvular leaflets. […] It is generally assumed that most cardiac lipomas are silent and only a small proportion of this entity may show clinical symptoms depending on their location and size. However, among the included cases, only in 97 patients (97/255, 38.0%) were cardiac lipomas found incidentally without related symptoms. […] Symptoms related to cardiac lipoma were presented in 147 patients (147/255, 57.6%) ranging from mild chest discomfort to sudden death. […] The size of the cardiac lipoma varied with distribution. In general, pericardial lipomas may grow extensively within the pericardial sac and shared larger size than intracavitary and myocardial lipomas.

• #74 A Rare Case of Incidental Tracheal Lipoma | Archivos de Bronconeumología

  https://www.archbronconeumol.org/en-a-rare-case-incidental-tracheal-articulo-S0300289618301509

  Primary tracheal tumours are uncommon, with an incidence of 0.2/100000 population.1 […] Tracheal lipoma is extremely rare and only few cases have been reported in the literature.18 […] Airways lipoma is a remarkably rare tumour, representing only 3.2%9.5% of tracheobronchial tree benign neoplasms.3 […] Patients with tracheal lipoma are primarily middle-aged men.3 […] To date, ours is the second case of asymptomatic tracheal lipoma reported in the literature. […] The gold standard in the diagnosis of tracheal lipoma is the flexible tracheobronchoscopy. […] The treatment of tracheal lipoma is its excision by tracheobronchoscopy or, in select cases, by tracheal resection with end-to-end anastomosis. […] Tracheal lipoma is an infrequent finding that may be considered as one of the possible alternative diagnoses of treatment-resistant asthma and chronic bronchitis.

• #75 A Rare Case of Incidental Tracheal Lipoma | Archivos de Bronconeumología

  https://archbronconeumol.org/en-a-rare-case-incidental-tracheal-articulo-S0300289618301509

  Primary tracheal tumours are uncommon, with an incidence of 0.2/100000 population.1 […] Tracheal lipoma is extremely rare and only few cases have been reported in the literature.18 […] Airways lipoma is a remarkably rare tumour, representing only 3.2%9.5% of tracheobronchial tree benign neoplasms.3 […] Patients with tracheal lipoma are primarily middle-aged men.3 […] To date, ours is the second case of asymptomatic tracheal lipoma reported in the literature. […] The gold standard in the diagnosis of tracheal lipoma is the flexible tracheobronchoscopy. […] The treatment of tracheal lipoma is its excision by tracheobronchoscopy or, in select cases, by tracheal resection with end-to-end anastomosis. […] So far, no local recurrence has been reported after endoscopic treatment. […] Tracheal lipoma is an infrequent finding that may be considered as one of the possible alternative diagnoses of treatment-resistant asthma and chronic bronchitis. The endoscopic treatment of tracheal lipoma is effective and safe. It should be recommended as the first approach to restore tracheal clearance.

• #76 A Rare Case of Incidental Tracheal Lipoma | Archivos de Bronconeumología

  https://www.archbronconeumol.org/en-a-rare-case-incidental-tracheal-articulo-S0300289618301509

  Primary tracheal tumours are uncommon, with an incidence of 0.2/100000 population.1 […] Tracheal lipoma is extremely rare and only few cases have been reported in the literature.18 […] Airways lipoma is a remarkably rare tumour, representing only 3.2%9.5% of tracheobronchial tree benign neoplasms.3 […] Patients with tracheal lipoma are primarily middle-aged men.3 […] To date, ours is the second case of asymptomatic tracheal lipoma reported in the literature. […] The gold standard in the diagnosis of tracheal lipoma is the flexible tracheobronchoscopy. […] The treatment of tracheal lipoma is its excision by tracheobronchoscopy or, in select cases, by tracheal resection with end-to-end anastomosis. […] Tracheal lipoma is an infrequent finding that may be considered as one of the possible alternative diagnoses of treatment-resistant asthma and chronic bronchitis.

• #77 Lipomas of the nervous system | MedLink Neurology

  https://www.medlink.com/articles/lipomas-of-the-nervous-system

  As intracranial and intraspinal lipomas are rare, their true incidence and prevalence are unknown. […] Two autopsy series from 1944 and 1974 report lipomas in 4 of 5000 (0.08%) and 9 of 1956 (0.46%) brain autopsies, though autopsy selection criteria were not clear. […] Among 3200 patients with brain tumors studied by CT, Kazner and colleagues counted only 11 lipoma cases (0.34%). […] A survey of 319 cases of primary intracranial tumors in children counted no cases of lipoma. […] Cerebellopontine angle lipomas account for up to 1% of cerebellopontine angle tumors. […] Intraspinal lipomas are also often discovered in asymptomatic patients but are found more much more frequently than their intracranial counterparts. […] Lipomas of the filum terminale are found in 4% to 6% of cases in postmortem series.

• #78 Lipomas of the nervous system | MedLink Neurology

  https://www.medlink.com/articles/lipomas-of-the-nervous-system

  As intracranial and intraspinal lipomas are rare, their true incidence and prevalence are unknown. […] Two autopsy series from 1944 and 1974 report lipomas in 4 of 5000 (0.08%) and 9 of 1956 (0.46%) brain autopsies, though autopsy selection criteria were not clear. […] Among 3200 patients with brain tumors studied by CT, Kazner and colleagues counted only 11 lipoma cases (0.34%). […] A survey of 319 cases of primary intracranial tumors in children counted no cases of lipoma. […] Cerebellopontine angle lipomas account for up to 1% of cerebellopontine angle tumors. […] Intraspinal lipomas are also often discovered in asymptomatic patients but are found more much more frequently than their intracranial counterparts. […] Lipomas of the filum terminale are found in 4% to 6% of cases in postmortem series.

• #79 Lipomas of the nervous system | MedLink Neurology

  https://www.medlink.com/articles/lipomas-of-the-nervous-system

  As intracranial and intraspinal lipomas are rare, their true incidence and prevalence are unknown. […] Two autopsy series from 1944 and 1974 report lipomas in 4 of 5000 (0.08%) and 9 of 1956 (0.46%) brain autopsies, though autopsy selection criteria were not clear. […] Among 3200 patients with brain tumors studied by CT, Kazner and colleagues counted only 11 lipoma cases (0.34%). […] A survey of 319 cases of primary intracranial tumors in children counted no cases of lipoma. […] Cerebellopontine angle lipomas account for up to 1% of cerebellopontine angle tumors. […] Intraspinal lipomas are also often discovered in asymptomatic patients but are found more much more frequently than their intracranial counterparts. […] Lipomas of the filum terminale are found in 4% to 6% of cases in postmortem series.

• #80 Parapharyngeal space lipoma: a case report | HKMJ

  https://www.hkmj.org/abstracts/v26n5/438.htm

  Parapharyngeal space (PPS) tumours account for only around 0.5% of tumours in the head and neck region. […] Lipomas in the PPS are rare, despite being the most common benign mesenchymal head and neck tumour. […] Most PPS lipomas grow insidiously and cause symptoms only when exerting mass effects as seen in any other benign tumours, for example, dysphagia, shortness of breath, and obstructive sleep apnoea. […] Diagnostic FNAC is often technically difficult as the PPS lipoma is deep-seated. […] Most of the time, imaging such as computed tomography (CT) and MRI has significant diagnostic significance. […] Surgical excision is the treatment of choice. […] A transcervical approach is most widely applied and is particularly suitable for smaller PPS tumours. […] A transcervical approach is combined with a transmandibular approach when dealing with larger lesions involving the skull base and the aforementioned lower cranial nerves for better exposure, while an infratemporal approach is used when access to the lateral part of the skull base is necessary.

• #81 JMIR Dermatology – Patterns of Public Interest in Lipomas and Lipoma-Removal Procedures: Google Trends Analysis

  https://derma.jmir.org/2025/1/e62993

  On average, interest in lipoma removal has been relatively higher in non-coastal Western states. […] This study leveraged Google Trends data to show that public interest in lipomas and lipoma-associated topics, while comparatively lower than that for other common dermatological conditions, has increased both in the United States and internationally over the past 20 years. Additionally, the interest in lipoma removal procedures has increased substantially over the past 20 years in the United States. […] Irrespective of the cause, increasing public interest in lipomas indicates a need for clinicians to be vigilant, prepared to encounter the condition, and comfortable with educating their patients about it.

• #82 JMIR Dermatology – Patterns of Public Interest in Lipomas and Lipoma-Removal Procedures: Google Trends Analysis

  https://derma.jmir.org/2025/1/e62993

  Over the past 20 years, public interest in lipomas was consistently lower than that in 4 other common dermatological conditions: atopic dermatitis, psoriasis, skin cancer, and rosacea. […] Lipoma-associated interest was the highest in pockets of Eastern Europe and Asia. […] Specifically, the countries with the highest RSV for the lipoma condition were Turkey, Russia, Belarus, Kazakhstan, and Ukraine, with RSVs of 100, 84, 80, 78, and 68, respectively. Comparatively, the United States had an RSV of 41 for the same query. […] Here, public interest in lipomas was the highest in Southern and Midwestern states. […] There was a clear and consistent increase in Google searches containing both of the terms lipoma and removal from the mid-2000s onwards, interrupted only by a transient decline during the COVID-19 pandemic.

• #83 JMIR Dermatology – Patterns of Public Interest in Lipomas and Lipoma-Removal Procedures: Google Trends Analysis

  https://derma.jmir.org/2025/1/e62993

  Over the past 20 years, public interest in lipomas was consistently lower than that in 4 other common dermatological conditions: atopic dermatitis, psoriasis, skin cancer, and rosacea. […] Lipoma-associated interest was the highest in pockets of Eastern Europe and Asia. […] Specifically, the countries with the highest RSV for the lipoma condition were Turkey, Russia, Belarus, Kazakhstan, and Ukraine, with RSVs of 100, 84, 80, 78, and 68, respectively. Comparatively, the United States had an RSV of 41 for the same query. […] Here, public interest in lipomas was the highest in Southern and Midwestern states. […] There was a clear and consistent increase in Google searches containing both of the terms lipoma and removal from the mid-2000s onwards, interrupted only by a transient decline during the COVID-19 pandemic.

• #84 JMIR Dermatology – Patterns of Public Interest in Lipomas and Lipoma-Removal Procedures: Google Trends Analysis

  https://derma.jmir.org/2025/1/e62993

  Over the past 20 years, public interest in lipomas was consistently lower than that in 4 other common dermatological conditions: atopic dermatitis, psoriasis, skin cancer, and rosacea. […] Lipoma-associated interest was the highest in pockets of Eastern Europe and Asia. […] Specifically, the countries with the highest RSV for the lipoma condition were Turkey, Russia, Belarus, Kazakhstan, and Ukraine, with RSVs of 100, 84, 80, 78, and 68, respectively. Comparatively, the United States had an RSV of 41 for the same query. […] Here, public interest in lipomas was the highest in Southern and Midwestern states. […] There was a clear and consistent increase in Google searches containing both of the terms lipoma and removal from the mid-2000s onwards, interrupted only by a transient decline during the COVID-19 pandemic.

• #85 JMIR Dermatology – Patterns of Public Interest in Lipomas and Lipoma-Removal Procedures: Google Trends Analysis

  https://derma.jmir.org/2025/1/e62993

  On average, interest in lipoma removal has been relatively higher in non-coastal Western states. […] This study leveraged Google Trends data to show that public interest in lipomas and lipoma-associated topics, while comparatively lower than that for other common dermatological conditions, has increased both in the United States and internationally over the past 20 years. Additionally, the interest in lipoma removal procedures has increased substantially over the past 20 years in the United States. […] Irrespective of the cause, increasing public interest in lipomas indicates a need for clinicians to be vigilant, prepared to encounter the condition, and comfortable with educating their patients about it.

• #86 Lipoma Pathology – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK482343/

  Lipomas are defined as a common subcutaneous tumor composed of adipose (fat) cells, often encapsulated by a thin layer of fibrous tissue. […] The prevalence of lipomas has been cited as affecting 1% of the population, while its incidence, which is possibly underreported, is 2.1 per 1000 individuals per year. […] If lipomas are not painful and harmless, there is no need for removal.

• #87 Lipoma and Atypical Lipomatous Tumors – OrthoInfo – AAOS

  https://orthoinfo.aaos.org/en/diseases–conditions/lipoma

  Some doctors think that lipomas occur more often in inactive people. […] Doctors can usually diagnose lipomas based on history and physical examination alone. […] While lipomas and atypical lipomatous tumors are not considered cancerous, liposarcomas are cancerous. […] People with lipomas are not more likely to develop a fatty cancer in the future. […] Because lipomas are benign (not cancerous) tumors, no treatment may be an option, depending on your symptoms. […] Most surgeons recommend some sort of surveillance after tumor removal. This usually involves a physical exam and imaging every 6 to 12 months.

• #88 Benign skin tumors – Knowledge @ AMBOSS

  https://www.amboss.com/us/knowledge/benign-skin-tumors/

  Most common soft tissue tumor […] Prevalence: 1% […] A lipoma is a common, benign, soft tissue mesenchymal tumor, usually subcutaneous. […] Diagnosis is typically clinical. […] If excised, recurrence occurs in of cases. […] No malignant potential.

• #89

  https://journals.lww.com/ajg/fulltext/2021/10001/s3711_gastric_lipoma_in_a_patient_with_symptomatic.3715.aspx

  Gastric lipomas are very rare, accounting for 5% percent of all gastrointestinal lipomas, and 3% of all benign gastric tumors. […] Asymptomatic lipomas are managed expectantly, and do not require surveillance because malignant transformation is rare. […] In contrast, lipomas that are symptomatic or cause bleeding or obstruction, are usually surgically removed.

• #90 Lipoma (fatty lumps)

  https://dermnetnz.org/topics/lipoma

  While lipomas typically affect patients between 40 and 60 years of age, they can occur at any age and are more common in patients with hyperlipidaemia, type 2 diabetes mellitus, and obesity. Both sexes are equally affected. […] Local recurrence is rare with excision and malignant transformation is exceedingly rare.

• #91 Lipoma and Atypical Lipomatous Tumors – OrthoInfo – AAOS

  https://orthoinfo.aaos.org/en/diseases–conditions/lipoma

  Some doctors think that lipomas occur more often in inactive people. […] Doctors can usually diagnose lipomas based on history and physical examination alone. […] While lipomas and atypical lipomatous tumors are not considered cancerous, liposarcomas are cancerous. […] People with lipomas are not more likely to develop a fatty cancer in the future. […] Because lipomas are benign (not cancerous) tumors, no treatment may be an option, depending on your symptoms. […] Most surgeons recommend some sort of surveillance after tumor removal. This usually involves a physical exam and imaging every 6 to 12 months.

• #92 Benign skin tumors – Knowledge @ AMBOSS

  https://www.amboss.com/us/knowledge/benign-skin-tumors/

  Most common soft tissue tumor […] Prevalence: 1% […] A lipoma is a common, benign, soft tissue mesenchymal tumor, usually subcutaneous. […] Diagnosis is typically clinical. […] If excised, recurrence occurs in of cases. […] No malignant potential.

• #93 Lipomas are benign masses caused by overgrowth of fat cells | UCLA Health

  https://www.uclahealth.org/news/article/lipomas-are-benign-masses-caused-by-overgrowth-of-fat-cells

  Lipomas are typically found just below the surface of the skin, often on the trunk, neck, limbs or forehead. […] It is estimated that 1% to 2% of people will develop a lipoma in their lifetime. […] Lipomas occur slightly more often in men than in women, and although they can appear at any age, they become more common in adults between the ages of 40 and 70. […] While its possible for a lipoma to become malignant, this is quite rare. […] It is rare for a lipoma that has been surgically removed to recur.

• #94 Soft Tissue Masses: Evaluation and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2022/0600/p602.html

  Lipomas are soft, fatty deposits that account for approximately one-half of benign soft tissue masses. Lipomas can develop at any age, with a predilection for the trunk and proximal extremities, although they are most common in patients who are 40 to 70 years of age or obese. Presentation in children is often varied and nonspecific, and lesions can grow rapidly during periods of weight gain. Patients who have family members with multiple lipomas may have a genetic condition called familial multiple lipomatosis, which presents with multiple benign lipomas on the extremities or trunk. Because some lipomas are deep to the fascia, they can be larger than what is felt on palpation. […] Lipomas are usually benign and can be treated with monitoring. Lipomas that are 5 cm or larger in diameter or have atypical features on MRI, such as septations thicker than 2 mm or nodular soft tissue changes, should be evaluated for surgical excision. Excision can be considered for lipomas that are painful or fast growing and for cosmetic reasons. Lipomas have a low rate of recurrence after excision, but possible complications include adhesions, scarring, muscle injury, and permanent nerve damage.

• #95 Soft Tissue Masses: Evaluation and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2022/0600/p602.html

  Lipomas are soft, fatty deposits that account for approximately one-half of benign soft tissue masses. Lipomas can develop at any age, with a predilection for the trunk and proximal extremities, although they are most common in patients who are 40 to 70 years of age or obese. Presentation in children is often varied and nonspecific, and lesions can grow rapidly during periods of weight gain. Patients who have family members with multiple lipomas may have a genetic condition called familial multiple lipomatosis, which presents with multiple benign lipomas on the extremities or trunk. Because some lipomas are deep to the fascia, they can be larger than what is felt on palpation. […] Lipomas are usually benign and can be treated with monitoring. Lipomas that are 5 cm or larger in diameter or have atypical features on MRI, such as septations thicker than 2 mm or nodular soft tissue changes, should be evaluated for surgical excision. Excision can be considered for lipomas that are painful or fast growing and for cosmetic reasons. Lipomas have a low rate of recurrence after excision, but possible complications include adhesions, scarring, muscle injury, and permanent nerve damage.

• #96 Incidental finding of left ventricle lipoma in the setting of metastatic cancer: Is the decision of surveillance appropriate based on imaging alone? – JTCVS Techniques

  https://www.jtcvstechniques.org/article/S2666-2507(23)00217-1/fulltext

  Preliminary diagnosis of cardiac tumor using history and imaging characteristics can justify surveillance over immediate operative intervention in the appropriate setting. […] Incidence of these tumors in multiple autopsy series range from 0.2% to 0.4%. […] Cardiac lipomas account for 8.4% of these tumors and have been documented in all chambers of the heart and valve leaflets. […] The diagnosis of cardiac tumors is often based on patient history and imaging alone due to the difficulty of obtaining a biopsy. […] The imaging techniques that help delineate benign from malignant tumors include echocardiography, cardiac CT, and MRI. […] Definitive diagnosis cannot be made until surgery is performed and final pathology obtained. […] This raises a question: In an asymptomatic patient with metastatic cancer, is it safe to conclude whether or not a cardiac tumor is primary, secondary, malignant, benign, or even a thrombus based on imaging characteristics alone? […] History and imaging characteristics of a benign cardiac tumor in an asymptomatic patient provide satisfactory evidence to justify postponing treatment.

• #97 Incidental finding of left ventricle lipoma in the setting of metastatic cancer: Is the decision of surveillance appropriate based on imaging alone? – JTCVS Techniques

  https://www.jtcvstechniques.org/article/S2666-2507(23)00217-1/fulltext

  Preliminary diagnosis of cardiac tumor using history and imaging characteristics can justify surveillance over immediate operative intervention in the appropriate setting. […] Incidence of these tumors in multiple autopsy series range from 0.2% to 0.4%. […] Cardiac lipomas account for 8.4% of these tumors and have been documented in all chambers of the heart and valve leaflets. […] The diagnosis of cardiac tumors is often based on patient history and imaging alone due to the difficulty of obtaining a biopsy. […] The imaging techniques that help delineate benign from malignant tumors include echocardiography, cardiac CT, and MRI. […] Definitive diagnosis cannot be made until surgery is performed and final pathology obtained. […] This raises a question: In an asymptomatic patient with metastatic cancer, is it safe to conclude whether or not a cardiac tumor is primary, secondary, malignant, benign, or even a thrombus based on imaging characteristics alone? […] History and imaging characteristics of a benign cardiac tumor in an asymptomatic patient provide satisfactory evidence to justify postponing treatment.

• #98 Incidental finding of left ventricle lipoma in the setting of metastatic cancer: Is the decision of surveillance appropriate based on imaging alone? – JTCVS Techniques

  https://www.jtcvstechniques.org/article/S2666-2507(23)00217-1/fulltext

  Preliminary diagnosis of cardiac tumor using history and imaging characteristics can justify surveillance over immediate operative intervention in the appropriate setting. […] Incidence of these tumors in multiple autopsy series range from 0.2% to 0.4%. […] Cardiac lipomas account for 8.4% of these tumors and have been documented in all chambers of the heart and valve leaflets. […] The diagnosis of cardiac tumors is often based on patient history and imaging alone due to the difficulty of obtaining a biopsy. […] The imaging techniques that help delineate benign from malignant tumors include echocardiography, cardiac CT, and MRI. […] Definitive diagnosis cannot be made until surgery is performed and final pathology obtained. […] This raises a question: In an asymptomatic patient with metastatic cancer, is it safe to conclude whether or not a cardiac tumor is primary, secondary, malignant, benign, or even a thrombus based on imaging characteristics alone? […] History and imaging characteristics of a benign cardiac tumor in an asymptomatic patient provide satisfactory evidence to justify postponing treatment.

• #99 From pathogenesis to treatment, a systemic review of cardiac lipoma | Journal of Cardiothoracic Surgery | Full Text

  https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-020-01379-6

  The distribution within the heart suggests that around 48.7% lipomas arise from the subendomyocardium, 32.5% from subpericardium, 10.7% from myocardium and 4.4% from cardiac valvular leaflets. […] It is generally assumed that most cardiac lipomas are silent and only a small proportion of this entity may show clinical symptoms depending on their location and size. However, among the included cases, only in 97 patients (97/255, 38.0%) were cardiac lipomas found incidentally without related symptoms. […] Symptoms related to cardiac lipoma were presented in 147 patients (147/255, 57.6%) ranging from mild chest discomfort to sudden death. […] The size of the cardiac lipoma varied with distribution. In general, pericardial lipomas may grow extensively within the pericardial sac and shared larger size than intracavitary and myocardial lipomas.

• #100 From pathogenesis to treatment, a systemic review of cardiac lipoma | Journal of Cardiothoracic Surgery | Full Text

  https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-020-01379-6

  There is no guideline on the treatment of cardiac lipoma. Since the first successful removal of a pericardial lipoma reported in 1952, more and more symptomatic cardiac lipomas have been resected. […] Among the included reports, most symptomatic patients (83.7%, 123/147) underwent resection of cardiac lipomas.

• #101

  https://journals.lww.com/ajg/fulltext/2018/10001/the_ball_in_socket_lesion__a_case_report_of_an.1648.aspx

  Lipomas of the gastrointestinal tract are the second most common benign lesions, with 70% occurring in the colon, particularly on the right side. Majority of lipomas are asymptomatic, have low risk of malignancy transformation and are discovered incidentally on routine colonoscopy. […] Our case adds to the literature available on colonic lipomas, however highlights an interesting case of a large asymptomatic extremely mobile lipoma originating from the ileocecal valve with the ability to extend into the terminal ileum in a ball-in-socket fashion. Reassuringly, the patient was asymptomatic, and thus watchful waiting was recommended without need for immediate resection. Our case also highlights the utility of stacked biopsies of benign appearing submucosal lesions to aid in the diagnosis and the importance of terminal ileum examination during colonoscopy.

• #102

  https://journals.lww.com/ajg/fulltext/2021/10001/s3711_gastric_lipoma_in_a_patient_with_symptomatic.3715.aspx

  Gastric lipomas are very rare, accounting for 5% percent of all gastrointestinal lipomas, and 3% of all benign gastric tumors. […] Asymptomatic lipomas are managed expectantly, and do not require surveillance because malignant transformation is rare. […] In contrast, lipomas that are symptomatic or cause bleeding or obstruction, are usually surgically removed.

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