Materiały źródłowe

• #1 Lipoma – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507906/

  Lipomas are common, benign subcutaneous tumors of fat cells (adipocytes) that present as soft, painless nodules that are most commonly seen on the trunk. They are benign and have many histologic subtypes. The presence of multiple lipomas may be the presenting feature of a variety of syndromes. […] Lipomas are benign tumors of fat cells (adipocytes) that present as soft, painless masses most commonly seen on the trunk, but can be located anywhere on the body. […] Lipomas represent the most common mesenchymal tumors of the human body. About 1 in every thousand persons will have lipoma at some point in their lifetime. […] The exact pathophysiology of lipomas is unclear. However, benign lipomas can be present in almost any organ of the body. […] Histologic examination of lipomas reveals mature, normal-appearing adipocytes with a small eccentric nucleus.

• #2 Lipoma: What Is It, Causes, Symptoms, Types, Treatment

  https://my.clevelandclinic.org/health/diseases/15008-lipomas

  Most lipomas dont need treatment. If a lipoma is bothering you, your provider can remove it surgically. Lipoma removal procedures are safe and effective, and you can usually go home the same day. […] Many people live with lipomas, and they may not even notice them. Most lipomas dont need treatment, but providers can remove them if necessary. Lipomas rarely grow back after lipoma treatment, but another one may grow in a different spot on your body. […] If you have a skin growth, lump or knot under your skin, see your provider. Its essential to get evaluated and rule out serious conditions, such as liposarcoma (a type of cancer). Symptoms of liposarcoma are similar to signs of a lipoma.

• #3 Lipoma – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/lipoma/diagnosis-treatment/drc-20374474

  To diagnose a lipoma, your doctor may perform: […] A biopsy or an MRI or CT scan is typically done if your doctor suspects liposarcoma. […] Lipoma treatments include: […] Most lipomas are removed surgically by cutting them out. Recurrences after removal are uncommon. […] A technique known as minimal excision extraction may result in less scarring. […] This treatment uses a needle and a large syringe to remove the fatty lump. […] For lipoma, some basic questions to ask include: […] Is it cancer? […] Do I need tests? […] Will this lump always be there? […] Can I have it removed? […] What’s involved in removing it? Are there risks? […] Is it likely to return, or am I likely to get another? […] Your doctor is likely to ask you questions, too, including: […] Has it grown? […] Is the lump painful?

• #4 Lipoma: What Is It, Causes, Symptoms, Types, Treatment

  https://my.clevelandclinic.org/health/diseases/15008-lipomas

  A lipoma is a lump of fatty tissue that grows just under the skin. Lipomas move easily when you touch them and feel rubbery, not hard. Most lipomas arent painful and don’t cause health problems so they rarely need treatment. If a lipoma is bothering you, your provider can remove it. […] Lipomas are benign soft tissue tumors. They grow slowly and are not cancerous. Most lipomas dont need treatment. If a lipoma is bothering you, your healthcare provider can remove it with an outpatient procedure. […] Providers usually diagnose a lipoma during a physical examination. Your provider will touch the lipoma and ask if its painful or tender. You may need a biopsy to confirm that the lipoma isnt cancer. During this procedure, your provider removes a sample of the lipoma and sends it to a lab for testing.

• #5 Lipoma Excision | AAFP

  https://www.aafp.org/pubs/afp/issues/2002/0301/p901.html

  Lipomas are adipose tumors that are often located in the subcutaneous tissues of the head, neck, shoulders, and back. Lipomas have been identified in all age groups but usually first appear between 40 and 60 years of age. These slow-growing, nearly always benign, tumors usually present as nonpainful, round, mobile masses with a characteristic soft, doughy feel. […] Most lipomas are asymptomatic, can be diagnosed with clinical examination and do not require treatment. […] Lipomas usually present as nonpainful, round, mobile masses, with a characteristic soft, doughy feel. The overlying skin appears normal. Lipomas can usually be correctly diagnosed by their clinical appearance alone. […] Malignancy is rare but can be found in a lesion with the clinical appearance of a lipoma. Liposarcoma presents in a fashion similar to that of a lipoma and appears to be more common in the retroperitoneum, and on the shoulders and lower extremities.

• #6 Lipoma – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507906/

  Lipomas typically present as soft, solitary, painless, subcutaneous nodules that are mobile and not associated with epidermal change. […] Common lipomas frequently are diagnosed clinically and are sent for histologic examination after complete surgical excision. […] The majority of the patients who seek treatment for lipomas are due to cosmetic reasons. […] The prognosis is excellent for benign lipomas. Recurrence is not common but may develop if the excision was incomplete. […] Gastrointestinal lipomas can cause obstructive symptoms and bleed secondary to ulceration. […] Lipomatous lesions arising in the midline sacrococcygeal region can be a manifestation of spinal dysraphism. […] Lipomas are commonly encountered by the primary care provider and nurse practitioner. However, definitive management is usually done by a dermatologist, general surgeon, or plastic surgeon.

• #7 Lipoma – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/lipoma/symptoms-causes/syc-20374470

  A lipoma is a slow-growing, fatty lump that’s most often situated between your skin and the underlying muscle layer. A lipoma, which feels doughy and usually isn’t tender, moves readily with slight finger pressure. Lipomas are usually detected in middle age. Some people have more than one lipoma. […] A lipoma isn’t cancer and usually is harmless. Treatment generally isn’t necessary, but if the lipoma bothers you, is painful or is growing, you may want to have it removed. […] A lipoma is a fatty tumor located just below the skin. It isn’t cancer and is usually harmless. […] A lipoma is rarely a serious medical condition. But if you notice a lump or swelling anywhere on your body, have it checked by your doctor. […] The cause of lipomas isn’t fully understood. They tend to run in families, so genetic factors likely play a role in their development. […] Several factors may increase your risk of developing a lipoma, including: Being between 40 and 60 years old. Although lipomas can occur at any age, they’re most common in this age group. […] Genetics. Lipomas tend to run in families.

• #8 Lipoma – Symptoms, diagnosis and treatment | BMJ Best Practice

  https://bestpractice.bmj.com/topics/en-gb/981

  Lipomas are benign tumours composed of adipose tissue. […] Lipomas usually arise in the subcutaneous tissues and may occur in any area of the body, although they most frequently occur on the trunk and proximal limbs. […] They have no malignant potential, but the differential diagnosis of liposarcoma must be considered. […] Surgical resection is indicated for symptomatic relief, pathological confirmation, or cosmetic reasons, or if there is an increase in size. […] Diagnostic investigations include ultrasound, MRI, CT scan, core needle biopsy, incisional biopsy, excisional biopsy, upper gastrointestinal contrast study, and gastrointestinal endoscopy.

• #9 Lipoma – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/lipoma/diagnosis-treatment/drc-20374474

  To diagnose a lipoma, your doctor may perform: […] A biopsy or an MRI or CT scan is typically done if your doctor suspects liposarcoma. […] Lipoma treatments include: […] Most lipomas are removed surgically by cutting them out. Recurrences after removal are uncommon. […] A technique known as minimal excision extraction may result in less scarring. […] This treatment uses a needle and a large syringe to remove the fatty lump. […] For lipoma, some basic questions to ask include: […] Is it cancer? […] Do I need tests? […] Will this lump always be there? […] Can I have it removed? […] What’s involved in removing it? Are there risks? […] Is it likely to return, or am I likely to get another? […] Your doctor is likely to ask you questions, too, including: […] Has it grown? […] Is the lump painful?

• #10 Atypical Sites of the Lipoma on the Hand and Fingers: Clinical and Imaging Features and Surgical Outcomes

  https://www.mdpi.com/2075-4418/12/10/2286

  Clinical features and diagnostic and surgical outcomes are analyzed and discussed. […] The diagnosis was made by clinical examination, using palpation to determine the consistency and mobility of the lesion and whether the pain was spontaneous or induced by palpation. […] Clinical examination makes the diagnosis of lipoma in approximately 85% of cases. […] Radiological examination can confirm the diagnosis in approximately 70% of cases. […] Most often, the combination of a clinical examination with radiological and ultrasound examinations leads to a diagnosis of lipoma. […] Surgical excision is the mainstay of treatment for lipomas, regardless of their location and size. […] Surgical treatment of smaller lipomas is indicated to avoid complications due to tumor growth (nerve compressions, carpal tunnel syndrome, and sensitivity disorders).

• #11 Soft Tissue Masses: Evaluation and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2022/0600/p602.html

  Signs that increase the risk of malignancy include tumor size of 5 cm or larger, location on or below the fascia, masses matted to surrounding structures, and rapid growth. […] Lipomas are soft, fatty deposits that account for approximately one-half of benign soft tissue masses. […] Lipomas can develop at any age, with a predilection for the trunk and proximal extremities, although they are most common in patients who are 40 to 70 years of age or obese. […] Patients who have family members with multiple lipomas may have a genetic condition called familial multiple lipomatosis, which presents with multiple benign lipomas on the extremities or trunk. […] Because some lipomas are deep to the fascia, they can be larger than what is felt on palpation. […] Lipomas that are 5 cm or larger in diameter or have atypical features on MRI, such as septations thicker than 2 mm or nodular soft tissue changes, should be evaluated for surgical excision. […] Excision can be considered for lipomas that are painful or fast growing and for cosmetic reasons. […] Lipomas have a low rate of recurrence after excision, but possible complications include adhesions, scarring, muscle injury, and permanent nerve damage.

• #12 Lipomas Workup: Laboratory Studies, Imaging Studies, Biopsy

  https://emedicine.medscape.com/article/191233-workup

  A study by Yoshiyama et al suggested that the plasma D-dimer level could contribute to the differentiation between lipoma and well-differentiated liposarcoma, two lesions that are similar in terms of clinical, radiologic, and pathologic characteristics. […] Imaging studies for lipomas in atypical locations (or those for which the differential diagnosis includes sarcoma) include ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI). […] When CT is employed, a radiodensity of less than 50 Hounsfield units is indicative of a soft-tissue tumor composed of fat, though no reliable distinction can be made between a benign lipoma and a malignant liposarcoma. […] MRI has been recommended as a reliable preoperative investigation. […] However, like CT, MRI does not allow an absolute, reliable distinction between a lipoma and a liposarcoma.

• #13 How Is a Lipoma Diagnosed? The Role of Ultrasound & Imaging

  https://www.theminorsurgerycenter.com/blog/how-is-a-lipoma-diagnosed

  Lipomas are non-cancerous, fatty lumps that can develop anywhere on the body where there is adipose (fat) tissue. Accurate diagnosis is crucial to determine the appropriate course of treatment and rule out other potential conditions. The diagnostic process for lipomas typically involves the following steps: Physical Examination, Ultrasound Imaging, Additional Imaging Techniques, and Biopsy (if necessary). Ultrasound is often the first imaging modality used to evaluate a suspected lipoma. Ultrasound offers several advantages in the diagnosis of lipomas: Non-invasive and radiation-free, Real-time imaging, Differentiation from other masses, Evaluation of vascularity, Cost-effective and widely available. On ultrasound, lipomas typically appear as well-defined, oval or round masses with a distinct capsule. While these characteristics are suggestive of a lipoma, additional imaging or biopsy may be recommended in some cases to confirm the diagnosis or rule out other potential concerns. In some cases, your healthcare provider may recommend additional imaging techniques to further evaluate a suspected lipoma or to clarify any ambiguous findings from the ultrasound. A biopsy may be recommended to confirm the diagnosis of a lipoma or to rule out other potential concerns, such as malignancy (cancer). The type of biopsy recommended will depend on the size, location, and characteristics of the lump, as well as any potential concerns raised by the imaging findings. Accurate diagnosis is crucial for determining the appropriate course of treatment for lipomas. Ultrasound plays a vital role in the diagnostic process, providing valuable information about the size, location, and characteristics of these fatty lumps.

• #14 How Is a Lipoma Diagnosed? The Role of Ultrasound & Imaging

  https://www.theminorsurgerycenter.com/blog/how-is-a-lipoma-diagnosed

  Lipomas are non-cancerous, fatty lumps that can develop anywhere on the body where there is adipose (fat) tissue. Accurate diagnosis is crucial to determine the appropriate course of treatment and rule out other potential conditions. The diagnostic process for lipomas typically involves the following steps: Physical Examination, Ultrasound Imaging, Additional Imaging Techniques, and Biopsy (if necessary). Ultrasound is often the first imaging modality used to evaluate a suspected lipoma. Ultrasound offers several advantages in the diagnosis of lipomas: Non-invasive and radiation-free, Real-time imaging, Differentiation from other masses, Evaluation of vascularity, Cost-effective and widely available. On ultrasound, lipomas typically appear as well-defined, oval or round masses with a distinct capsule. While these characteristics are suggestive of a lipoma, additional imaging or biopsy may be recommended in some cases to confirm the diagnosis or rule out other potential concerns. In some cases, your healthcare provider may recommend additional imaging techniques to further evaluate a suspected lipoma or to clarify any ambiguous findings from the ultrasound. A biopsy may be recommended to confirm the diagnosis of a lipoma or to rule out other potential concerns, such as malignancy (cancer). The type of biopsy recommended will depend on the size, location, and characteristics of the lump, as well as any potential concerns raised by the imaging findings. Accurate diagnosis is crucial for determining the appropriate course of treatment for lipomas. Ultrasound plays a vital role in the diagnostic process, providing valuable information about the size, location, and characteristics of these fatty lumps.

• #15 Lipoma Pathology – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK482343/

  A positive diagnosis of a lipoma typically involve the following: Physical exam performed by a medical doctor, An ultrasound of the mass should show that the lipoma or adipose mass is deeper than the surrounding fatty tissue, as well as, exhibiting dissimilar features as compared to the healthy/normal adipose tissue present, A biopsy (and subsequent analysis of a tissue sample) is not systematically done in routine practice as the diagnosis is generally made clinically, and since it may be difficult to distinguish lipomas from healthy adipose tissue, histologically speaking. […] The prognosis for benign lipomas is very good. These are benign entities and carry no risk for malignant transformation. Once these tumors are excised, mainly for cosmetic reasons, they often do not return. However, it is imperative that the fibrous capsule surrounding the lipoma is entirely removed to prevent such from happening.

• #16

  https://rms.cornwall.nhs.uk/primary_care_clinical_referral_criteria/primary_care_clinical_referral_criteria/general_surgery/lipoma

  Diagnosis of lipoma is usually clinical. Except those whereby sarcoma is suspected and fast track referral is recommended, ultrasound is not routinely required to confirm the diagnosis of benign lipoma. […] In the absence of red flags or high suspicion of sarcoma, ultrasound is not routinely required to confirm the diagnosis. […] Refer fast track suspected sarcoma if: Unexplained lump which is increasing in size, Ultrasound or other imaging findings are suggestive of soft tissue sarcoma, Ultrasound or other imaging findings are uncertain and clinical concern persists.

• #17 Lipoma | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/lipoma?lang=us

  Lipomas are benign tumors composed of mature adipocytes. They are the most common soft tissue tumor, seen in ~2% of the population. […] Diagnostic criteria according to the WHO classification of soft tissue and bone tumors (5th edition): essential: yellow-tan circumscribed mass; uniform proliferation of mature adipose tissue with atypical hyperchromatic stromal cells; desirable: absence of giant marker/ring chromosomes / MDM2 amplification. […] MRI is the modality of choice for imaging lipomas, not only to confirm the diagnosis, which is usually strongly suggested by ultrasound and CT but also to better assess for atypical features suggesting liposarcoma. Additionally, MRI is better able to demonstrate the surrounding anatomy. […] When no suspicious features are present, the diagnosis of lipoma can be made with confidence with MRI being 100% specific. Similarly, if suspicious features are present, then the sensitivity of MRI is 100%, although specificity is lower, as some masses with atypical features will nonetheless be lipomas.

• #18 Lipoma and Atypical Lipomatous Tumors – OrthoInfo – AAOS

  https://orthoinfo.aaos.org/en/diseases–conditions/lipoma

  Lipoma and Atypical Lipomatous Tumors […] A lipoma is a benign (noncancerous) tumor made up of fat tissue. It is the most common soft tissue tumor found in adults. […] They do not typically change after they form, and have very little potential for becoming cancerous. […] Atypical lipomatous tumors (ALT) are fatty tumors that can increase in size over time. […] ALT is a relatively new term for large atypical fatty tumors in the extremities (arms or legs). […] An ALT can be surgically removed, similar to a standard lipoma. […] Doctors can usually diagnose lipomas based on history and physical examination alone. However, imaging tests can be helpful for some cases. […] The best information for diagnosing lipomas comes from an MRI scan, which can create better images of soft tissues like a lipoma than an X-ray can.

• #19 The value of multimodality imaging in diagnosis and treatment of cardiac lipoma | BMC Medical Imaging | Full Text

  https://bmcmedimaging.biomedcentral.com/articles/10.1186/s12880-021-00603-6

  The clinical data and imaging findings of cardiac lipomas were described with special focus on the effect of cardiac imaging on clinical management. […] The diagnosis of cardiac lipoma was achieved with cardiac MRI in all cases, while only three of them were confirmed by pathology after surgical resection. […] Most cardiac lipomas can be accurately diagnosed using CT and MRI. […] The signal intensity of cardiac lipomas was consistent with that of subcutaneous fat in all MRI sequences, especially the characteristic complete signal loss of the mass in fat suppression sequence. […] Noninvasive cardiac imaging tools including CT and MRI, especially the latter, may be important in clinical decision making regarding cardiac lipomas. […] The imaging findings from MRI in patient 12 also significantly affected clinical decision making. […] Early detection and accurate diagnosis can be achieved with noninvasive imaging tools, especially MRI.

• #20 Lipoma | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/lipoma?lang=us

  Lipomas are benign tumors composed of mature adipocytes. They are the most common soft tissue tumor, seen in ~2% of the population. […] Diagnostic criteria according to the WHO classification of soft tissue and bone tumors (5th edition): essential: yellow-tan circumscribed mass; uniform proliferation of mature adipose tissue with atypical hyperchromatic stromal cells; desirable: absence of giant marker/ring chromosomes / MDM2 amplification. […] MRI is the modality of choice for imaging lipomas, not only to confirm the diagnosis, which is usually strongly suggested by ultrasound and CT but also to better assess for atypical features suggesting liposarcoma. Additionally, MRI is better able to demonstrate the surrounding anatomy. […] When no suspicious features are present, the diagnosis of lipoma can be made with confidence with MRI being 100% specific. Similarly, if suspicious features are present, then the sensitivity of MRI is 100%, although specificity is lower, as some masses with atypical features will nonetheless be lipomas.

• #21 A scoring system combining clinical, radiological, and histopathological examinations for differential diagnosis between lipoma and atypical lipomatous tumor/well-differentiated liposarcoma | Scientific Reports

  https://www.nature.com/articles/s41598-021-04004-1

  This study evaluated the diagnostic accuracy of clinical, radiological, and histopathological examinations for differential diagnosis between atypical lipomatous tumor (ALT)/well-differentiated liposarcoma (WDLS) and lipoma, and aimed to develop a new combined scoring system for the preoperative diagnosis of ALT/WDLS. […] The univariate and multivariate logistic regression analyses revealed that tumor location (lower extremity), deep site, size (11 cm), thick septa (2 mm), enhancement of septa or nodular lesions, and lipoblasts were significantly different for the diagnosis of ALT/WDLS. […] We developed a combined scoring system based on the six predictive factors (total 016 points, the cutoff was 9 points). […] This combined scoring system does not require special equipment and reagents such as fluorescence in situ hybridization (FISH), and anyone can use it easily in many medical institutions with high diagnostic accuracy.

• #22 Lipomas Workup: Laboratory Studies, Imaging Studies, Biopsy

  https://emedicine.medscape.com/article/191233-workup

  A study by Yoshiyama et al suggested that the plasma D-dimer level could contribute to the differentiation between lipoma and well-differentiated liposarcoma, two lesions that are similar in terms of clinical, radiologic, and pathologic characteristics. […] Imaging studies for lipomas in atypical locations (or those for which the differential diagnosis includes sarcoma) include ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI). […] When CT is employed, a radiodensity of less than 50 Hounsfield units is indicative of a soft-tissue tumor composed of fat, though no reliable distinction can be made between a benign lipoma and a malignant liposarcoma. […] MRI has been recommended as a reliable preoperative investigation. […] However, like CT, MRI does not allow an absolute, reliable distinction between a lipoma and a liposarcoma.

• #23 Lipomas Workup: Laboratory Studies, Imaging Studies, Biopsy

  https://emedicine.medscape.com/article/191233-workup

  A study by Yoshiyama et al suggested that the plasma D-dimer level could contribute to the differentiation between lipoma and well-differentiated liposarcoma, two lesions that are similar in terms of clinical, radiologic, and pathologic characteristics. […] Imaging studies for lipomas in atypical locations (or those for which the differential diagnosis includes sarcoma) include ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI). […] When CT is employed, a radiodensity of less than 50 Hounsfield units is indicative of a soft-tissue tumor composed of fat, though no reliable distinction can be made between a benign lipoma and a malignant liposarcoma. […] MRI has been recommended as a reliable preoperative investigation. […] However, like CT, MRI does not allow an absolute, reliable distinction between a lipoma and a liposarcoma.

• #24 The value of multimodality imaging in diagnosis and treatment of cardiac lipoma | BMC Medical Imaging | Full Text

  https://bmcmedimaging.biomedcentral.com/articles/10.1186/s12880-021-00603-6

  The clinical data and imaging findings of cardiac lipomas were described with special focus on the effect of cardiac imaging on clinical management. […] The diagnosis of cardiac lipoma was achieved with cardiac MRI in all cases, while only three of them were confirmed by pathology after surgical resection. […] Most cardiac lipomas can be accurately diagnosed using CT and MRI. […] The signal intensity of cardiac lipomas was consistent with that of subcutaneous fat in all MRI sequences, especially the characteristic complete signal loss of the mass in fat suppression sequence. […] Noninvasive cardiac imaging tools including CT and MRI, especially the latter, may be important in clinical decision making regarding cardiac lipomas. […] The imaging findings from MRI in patient 12 also significantly affected clinical decision making. […] Early detection and accurate diagnosis can be achieved with noninvasive imaging tools, especially MRI.

• #25 Lipoma Benign Lump | Other Conditions | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/other-conditions/lipoma

  A lipoma is a non cancerous (benign) lump that forms due to an overgrowth of fat cells. […] Lipomas are not cancer. Cancerous tumours of the fat cells are called liposarcomas. […] To make a diagnosis your doctor will feel and look at your lump. In most cases, your doctor can recognise and diagnose a lipoma easily. […] Rarely, doctors cant tell for certain whether the lump is a lipoma or not. Lipomas can be confused with malignant (cancerous) tumours, called liposarcomas. […] Your doctor may feel it is best to remove it or take a biopsy so that they can be certain it is a lipoma.

• #26 Lipomas: Symptoms, Causes and an FNA Diagnosis – Dr. Nadelman

  https://drnadelman.com/blog/lipomas-symptoms-causes-and-an-fna-diagnosis/

  A lipoma is one of those superficial lumps, like in the breast, that can cause a scare but actually turns out to be harmless. […] A procedure called a fine needle aspiration is the quickest, easiest way to set your mind at ease. […] An FNA biopsy is a quick, efficient method to diagnose a lipoma. […] The fine needle aspiration specialist inserts a very thin needle into the lipoma and withdraws some of the tissue or fluid. […] The specimen is examined under a microscope and if the results show only normal fat cells, the diagnosis is clear lipoma. […] An FNA biopsy is advantageous to the patient because it is minimally invasive and there is no downtime. […] Results are usually available within a day or two.

• #27 Lipomas: Symptoms, Causes and an FNA Diagnosis – Dr. Nadelman

  https://drnadelman.com/blog/lipomas-symptoms-causes-and-an-fna-diagnosis/

  A lipoma is one of those superficial lumps, like in the breast, that can cause a scare but actually turns out to be harmless. […] A procedure called a fine needle aspiration is the quickest, easiest way to set your mind at ease. […] An FNA biopsy is a quick, efficient method to diagnose a lipoma. […] The fine needle aspiration specialist inserts a very thin needle into the lipoma and withdraws some of the tissue or fluid. […] The specimen is examined under a microscope and if the results show only normal fat cells, the diagnosis is clear lipoma. […] An FNA biopsy is advantageous to the patient because it is minimally invasive and there is no downtime. […] Results are usually available within a day or two.

• #28 Lipoma: Symptoms, Causes, Stages, Diagnosis and Treatment – OncoDaily

  https://oncodaily.com/oncolibrary/cancer-types/lipoma

  When imaging results are inconclusive or suggest malignancy, a biopsy is warranted. Core needle biopsy (CNB) provides high diagnostic accuracy for adipocytic tumors, particularly for benign lipomatous tumors and higher-grade liposarcomas. A study by Taghipour et al. found that CNB offers strong diagnostic reliability for identifying malignant fat-containing tumors.

• #29 Lipoma: Symptoms, Causes, Stages, Diagnosis and Treatment – OncoDaily

  https://oncodaily.com/oncolibrary/cancer-types/lipoma

  When imaging results are inconclusive or suggest malignancy, a biopsy is warranted. Core needle biopsy (CNB) provides high diagnostic accuracy for adipocytic tumors, particularly for benign lipomatous tumors and higher-grade liposarcomas. A study by Taghipour et al. found that CNB offers strong diagnostic reliability for identifying malignant fat-containing tumors.

• #30 Lipomas Workup: Laboratory Studies, Imaging Studies, Biopsy

  https://emedicine.medscape.com/article/191233-workup

  A study by Yang et al found that imaging-based multimodality models using computer-assisted diagnostic models could be effective for discriminating between lipoma and well-differentiated liposarcoma. […] Biopsies are normally not indicated for small subcutaneous lesions, because the entire tumor is usually removed. […] Obtaining tissue samples from different tumor components is important, because it provides samples for histopathologic analysis by means of various techniques, including fluorescence in situ hybridization (FISH). […] Lipomas are benign mesenchymal tumors derived from adipocytes.

• #31 Lipoma – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK507906/

  Lipomas are common, benign subcutaneous tumors of fat cells (adipocytes) that present as soft, painless nodules that are most commonly seen on the trunk. They are benign and have many histologic subtypes. The presence of multiple lipomas may be the presenting feature of a variety of syndromes. […] Lipomas are benign tumors of fat cells (adipocytes) that present as soft, painless masses most commonly seen on the trunk, but can be located anywhere on the body. […] Lipomas represent the most common mesenchymal tumors of the human body. About 1 in every thousand persons will have lipoma at some point in their lifetime. […] The exact pathophysiology of lipomas is unclear. However, benign lipomas can be present in almost any organ of the body. […] Histologic examination of lipomas reveals mature, normal-appearing adipocytes with a small eccentric nucleus.

• #32 Lipoma: Symptoms, Causes, Diagnosis, and Removal Options – The Kingsley Clinic

  https://thekingsleyclinic.com/resources/lipoma-symptoms-causes-diagnosis-and-removal-options/

  Results from an MRI that indicate a lipoma typically show a well-circumscribed, homogeneous mass with signal characteristics similar to subcutaneous fat. […] Results from a CT scan that indicate a lipoma typically show a well-defined, homogeneous mass with low attenuation, similar to subcutaneous fat. […] Results from a biopsy that indicate a lipoma typically show mature adipose (fat) tissue with no atypical cells or signs of malignancy. […] Results from FNA that indicate a lipoma typically show mature adipose (fat) cells with no atypical features. […] Results from blood tests that indicate a lipoma are typically normal, as lipomas do not affect blood cell counts or organ function. […] Results from a PET scan that indicate a lipoma typically show low metabolic activity in the lump, consistent with benign fatty tissue.

• #33 Increasing differential diagnosis between lipoma and liposarcoma through radiomics: a narrative review

  https://www.explorationpub.com/Journals/etat/Article/1002147

  Increasing differential diagnosis between lipoma and liposarcoma through radiomics: a narrative review […] The diagnosis of these rare diseases with artificial intelligence (AI) techniques presents reduced datasets and therefore less robust methods. […] The combination of AI techniques with radiomics may be a new angle in diagnosing rare diseases such as STSs. […] Because of the similarity of ALT/WD-LPS/DD-LPS with lipoma at imaging today, genetic testing is the gold standard to distinguish lipoma from ALT/WD-LPS/DD-LPS. […] Murine double minute 2 (MDM2) amplification on fluorescence in situ hybridization (FISH) studies distinguishes ALT/WD-LPS from a lipoma, with 92% to 100% specificity and 97% to 100% sensitivity. […] The imaging findings of PM-LPS are typically a large, relatively well-defined, nonspecific soft tissue mass with often infiltrative margins and heterogeneous signal intensity due to the presence of hemorrhage and/or necrosis.

• #34 Increasing differential diagnosis between lipoma and liposarcoma through radiomics: a narrative review

  https://www.explorationpub.com/Journals/etat/Article/1002147

  Increasing differential diagnosis between lipoma and liposarcoma through radiomics: a narrative review […] The diagnosis of these rare diseases with artificial intelligence (AI) techniques presents reduced datasets and therefore less robust methods. […] The combination of AI techniques with radiomics may be a new angle in diagnosing rare diseases such as STSs. […] Because of the similarity of ALT/WD-LPS/DD-LPS with lipoma at imaging today, genetic testing is the gold standard to distinguish lipoma from ALT/WD-LPS/DD-LPS. […] Murine double minute 2 (MDM2) amplification on fluorescence in situ hybridization (FISH) studies distinguishes ALT/WD-LPS from a lipoma, with 92% to 100% specificity and 97% to 100% sensitivity. […] The imaging findings of PM-LPS are typically a large, relatively well-defined, nonspecific soft tissue mass with often infiltrative margins and heterogeneous signal intensity due to the presence of hemorrhage and/or necrosis.

• #35 A scoring system combining clinical, radiological, and histopathological examinations for differential diagnosis between lipoma and atypical lipomatous tumor/well-differentiated liposarcoma | Scientific Reports

  https://www.nature.com/articles/s41598-021-04004-1

  Based on these results, in adipocytic tumors, the differential diagnosis should be evaluated based on a comprehensive assessment of clinical, radiological, and histopathological examinations. […] In conclusion, we developed a new combined scoring system based on a comprehensive assessment of clinical, radiological, and histopathological examinations for the preoperative differential diagnosis between ALT/WDLS and lipoma. This scoring system had high diagnostic accuracy for differential diagnosis of ALT/WDLS and was a useful preoperative diagnostic tool that anyone can use easily in many medical institutions.

• #36 Lipoma | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/lipoma?lang=us

  Lipomas are benign tumors composed of mature adipocytes. They are the most common soft tissue tumor, seen in ~2% of the population. […] Diagnostic criteria according to the WHO classification of soft tissue and bone tumors (5th edition): essential: yellow-tan circumscribed mass; uniform proliferation of mature adipose tissue with atypical hyperchromatic stromal cells; desirable: absence of giant marker/ring chromosomes / MDM2 amplification. […] MRI is the modality of choice for imaging lipomas, not only to confirm the diagnosis, which is usually strongly suggested by ultrasound and CT but also to better assess for atypical features suggesting liposarcoma. Additionally, MRI is better able to demonstrate the surrounding anatomy. […] When no suspicious features are present, the diagnosis of lipoma can be made with confidence with MRI being 100% specific. Similarly, if suspicious features are present, then the sensitivity of MRI is 100%, although specificity is lower, as some masses with atypical features will nonetheless be lipomas.

• #37 Lipoma: Symptoms, Causes, Diagnosis, and Removal Options – The Kingsley Clinic

  https://thekingsleyclinic.com/resources/lipoma-symptoms-causes-diagnosis-and-removal-options/

  Results from an MRI that indicate a lipoma typically show a well-circumscribed, homogeneous mass with signal characteristics similar to subcutaneous fat. […] Results from a CT scan that indicate a lipoma typically show a well-defined, homogeneous mass with low attenuation, similar to subcutaneous fat. […] Results from a biopsy that indicate a lipoma typically show mature adipose (fat) tissue with no atypical cells or signs of malignancy. […] Results from FNA that indicate a lipoma typically show mature adipose (fat) cells with no atypical features. […] Results from blood tests that indicate a lipoma are typically normal, as lipomas do not affect blood cell counts or organ function. […] Results from a PET scan that indicate a lipoma typically show low metabolic activity in the lump, consistent with benign fatty tissue.

• #38 Lipomas Workup: Laboratory Studies, Imaging Studies, Biopsy

  https://emedicine.medscape.com/article/191233-workup

  A study by Yoshiyama et al suggested that the plasma D-dimer level could contribute to the differentiation between lipoma and well-differentiated liposarcoma, two lesions that are similar in terms of clinical, radiologic, and pathologic characteristics. […] Imaging studies for lipomas in atypical locations (or those for which the differential diagnosis includes sarcoma) include ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI). […] When CT is employed, a radiodensity of less than 50 Hounsfield units is indicative of a soft-tissue tumor composed of fat, though no reliable distinction can be made between a benign lipoma and a malignant liposarcoma. […] MRI has been recommended as a reliable preoperative investigation. […] However, like CT, MRI does not allow an absolute, reliable distinction between a lipoma and a liposarcoma.

• #39 Lipomas: Practice Essentials, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/191233-overview

  Lipomas are the most common soft-tissue tumor. These slow-growing, benign fatty tumors form soft, lobulated masses enclosed by a thin, fibrous capsule. Although it has been hypothesized that lipomas may rarely undergo sarcomatous change, this event has never been convincingly documented. It is more probable that lipomas are at the benign end of the spectrum of tumors, which, at the malignant end, include liposarcomas (see Pathophysiology). […] The plasma D-dimer level may help in distinguishing lipoma from well-differentiated liposarcoma. For most subcutaneous lipomas, no imaging studies are required. For lipomas in atypical locations (or for which the differential diagnosis includes sarcoma), ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI) may be considered. (See Workup.)

• #40 Lipoma Benign Lump | Other Conditions | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/other-conditions/lipoma

  A lipoma is a non cancerous (benign) lump that forms due to an overgrowth of fat cells. […] Lipomas are not cancer. Cancerous tumours of the fat cells are called liposarcomas. […] To make a diagnosis your doctor will feel and look at your lump. In most cases, your doctor can recognise and diagnose a lipoma easily. […] Rarely, doctors cant tell for certain whether the lump is a lipoma or not. Lipomas can be confused with malignant (cancerous) tumours, called liposarcomas. […] Your doctor may feel it is best to remove it or take a biopsy so that they can be certain it is a lipoma.

• #41 A scoring system combining clinical, radiological, and histopathological examinations for differential diagnosis between lipoma and atypical lipomatous tumor/well-differentiated liposarcoma | Scientific Reports

  https://www.nature.com/articles/s41598-021-04004-1

  This study evaluated the diagnostic accuracy of clinical, radiological, and histopathological examinations for differential diagnosis between atypical lipomatous tumor (ALT)/well-differentiated liposarcoma (WDLS) and lipoma, and aimed to develop a new combined scoring system for the preoperative diagnosis of ALT/WDLS. […] The univariate and multivariate logistic regression analyses revealed that tumor location (lower extremity), deep site, size (11 cm), thick septa (2 mm), enhancement of septa or nodular lesions, and lipoblasts were significantly different for the diagnosis of ALT/WDLS. […] We developed a combined scoring system based on the six predictive factors (total 016 points, the cutoff was 9 points). […] This combined scoring system does not require special equipment and reagents such as fluorescence in situ hybridization (FISH), and anyone can use it easily in many medical institutions with high diagnostic accuracy.

• #42 Soft Tissue Masses: Evaluation and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2022/0600/p602.html

  Signs that increase the risk of malignancy include tumor size of 5 cm or larger, location on or below the fascia, masses matted to surrounding structures, and rapid growth. […] Lipomas are soft, fatty deposits that account for approximately one-half of benign soft tissue masses. […] Lipomas can develop at any age, with a predilection for the trunk and proximal extremities, although they are most common in patients who are 40 to 70 years of age or obese. […] Patients who have family members with multiple lipomas may have a genetic condition called familial multiple lipomatosis, which presents with multiple benign lipomas on the extremities or trunk. […] Because some lipomas are deep to the fascia, they can be larger than what is felt on palpation. […] Lipomas that are 5 cm or larger in diameter or have atypical features on MRI, such as septations thicker than 2 mm or nodular soft tissue changes, should be evaluated for surgical excision. […] Excision can be considered for lipomas that are painful or fast growing and for cosmetic reasons. […] Lipomas have a low rate of recurrence after excision, but possible complications include adhesions, scarring, muscle injury, and permanent nerve damage.

• #43 Cardiac Lipoma: Diagnosis after Cardiac Arrest

  https://clinmedjournals.org/articles/cmrcr/clinical-medical-reviews-and-case-reports-cmrcr-6-267.php?jid=cmrcr

  Cardiac lipoma is a very rare primary benign tumor, with approximately 60 cases reported in the literature, with only six cases of lipoma originating from the interventricular septum. […] It is considered as a encapsulated neoplasm composed of mature fat cells and differentiated from the lipomatous hypertrophy of the septum in which there is a deposition of unencapsulated fat. Lipoma can occur anywhere in the heart, while lipomatous hypertrophy is limited to the septum. […] The present article reports the case of a 24-year-old woman who obtained this diagnosis after the manifestation of degenerated ventricular tachycardia for ventricular fibrillation. […] Pathological anatomy and immunohistochemistry confirmed the lipoma hypothesis. […] The authors emphasize the importance of lipoma as a differential diagnosis of cardiac arrest. Although they are rare, they can leads to complex ventricular arrhythmias and sudden death, successfully reversed in the present case.

• #44 A scoring system combining clinical, radiological, and histopathological examinations for differential diagnosis between lipoma and atypical lipomatous tumor/well-differentiated liposarcoma | Scientific Reports

  https://www.nature.com/articles/s41598-021-04004-1

  This study evaluated the diagnostic accuracy of clinical, radiological, and histopathological examinations for differential diagnosis between atypical lipomatous tumor (ALT)/well-differentiated liposarcoma (WDLS) and lipoma, and aimed to develop a new combined scoring system for the preoperative diagnosis of ALT/WDLS. […] The univariate and multivariate logistic regression analyses revealed that tumor location (lower extremity), deep site, size (11 cm), thick septa (2 mm), enhancement of septa or nodular lesions, and lipoblasts were significantly different for the diagnosis of ALT/WDLS. […] We developed a combined scoring system based on the six predictive factors (total 016 points, the cutoff was 9 points). […] This combined scoring system does not require special equipment and reagents such as fluorescence in situ hybridization (FISH), and anyone can use it easily in many medical institutions with high diagnostic accuracy.

• #45 A scoring system combining clinical, radiological, and histopathological examinations for differential diagnosis between lipoma and atypical lipomatous tumor/well-differentiated liposarcoma | Scientific Reports

  https://www.nature.com/articles/s41598-021-04004-1

  This study evaluated the diagnostic accuracy of clinical, radiological, and histopathological examinations for differential diagnosis between atypical lipomatous tumor (ALT)/well-differentiated liposarcoma (WDLS) and lipoma, and aimed to develop a new combined scoring system for the preoperative diagnosis of ALT/WDLS. […] The univariate and multivariate logistic regression analyses revealed that tumor location (lower extremity), deep site, size (11 cm), thick septa (2 mm), enhancement of septa or nodular lesions, and lipoblasts were significantly different for the diagnosis of ALT/WDLS. […] We developed a combined scoring system based on the six predictive factors (total 016 points, the cutoff was 9 points). […] This combined scoring system does not require special equipment and reagents such as fluorescence in situ hybridization (FISH), and anyone can use it easily in many medical institutions with high diagnostic accuracy.

• #46 Lipomas Workup: Laboratory Studies, Imaging Studies, Biopsy

  https://emedicine.medscape.com/article/191233-workup

  A study by Yang et al found that imaging-based multimodality models using computer-assisted diagnostic models could be effective for discriminating between lipoma and well-differentiated liposarcoma. […] Biopsies are normally not indicated for small subcutaneous lesions, because the entire tumor is usually removed. […] Obtaining tissue samples from different tumor components is important, because it provides samples for histopathologic analysis by means of various techniques, including fluorescence in situ hybridization (FISH). […] Lipomas are benign mesenchymal tumors derived from adipocytes.

• #47 The value of multimodality imaging in diagnosis and treatment of cardiac lipoma | BMC Medical Imaging | Full Text

  https://bmcmedimaging.biomedcentral.com/articles/10.1186/s12880-021-00603-6

  Cardiac lipoma is a rare primary tumor in the heart and pericardium. Multimodality imaging methods, especially magnetic resonance imaging (MRI), are crucial in detecting and diagnosing cardiac lipomas. […] The aim of this study was to evaluate the value of multimodality imaging methods in diagnosing and treatment of cardiac lipoma by describing a series of cases of cardiac lipoma. […] Accurate diagnoses were achieved with CT and MRI in all cases. […] Comprehensive evaluation with multimodality imaging methods should also be conducted for better management planning and follow-up in all patients. […] Nowadays, the detection and diagnosis of cardiac lipoma are highly dependent on noninvasive imaging methods including echocardiography, computed tomography (CT), and magnetic resonance imaging (MRI).

• #48 The value of multimodality imaging in diagnosis and treatment of cardiac lipoma | BMC Medical Imaging | Full Text

  https://bmcmedimaging.biomedcentral.com/articles/10.1186/s12880-021-00603-6

  The clinical data and imaging findings of cardiac lipomas were described with special focus on the effect of cardiac imaging on clinical management. […] The diagnosis of cardiac lipoma was achieved with cardiac MRI in all cases, while only three of them were confirmed by pathology after surgical resection. […] Most cardiac lipomas can be accurately diagnosed using CT and MRI. […] The signal intensity of cardiac lipomas was consistent with that of subcutaneous fat in all MRI sequences, especially the characteristic complete signal loss of the mass in fat suppression sequence. […] Noninvasive cardiac imaging tools including CT and MRI, especially the latter, may be important in clinical decision making regarding cardiac lipomas. […] The imaging findings from MRI in patient 12 also significantly affected clinical decision making. […] Early detection and accurate diagnosis can be achieved with noninvasive imaging tools, especially MRI.

• #49 The value of multimodality imaging in diagnosis and treatment of cardiac lipoma | BMC Medical Imaging | Full Text

  https://bmcmedimaging.biomedcentral.com/articles/10.1186/s12880-021-00603-6

  The clinical data and imaging findings of cardiac lipomas were described with special focus on the effect of cardiac imaging on clinical management. […] The diagnosis of cardiac lipoma was achieved with cardiac MRI in all cases, while only three of them were confirmed by pathology after surgical resection. […] Most cardiac lipomas can be accurately diagnosed using CT and MRI. […] The signal intensity of cardiac lipomas was consistent with that of subcutaneous fat in all MRI sequences, especially the characteristic complete signal loss of the mass in fat suppression sequence. […] Noninvasive cardiac imaging tools including CT and MRI, especially the latter, may be important in clinical decision making regarding cardiac lipomas. […] The imaging findings from MRI in patient 12 also significantly affected clinical decision making. […] Early detection and accurate diagnosis can be achieved with noninvasive imaging tools, especially MRI.

• #50 Intracranial lipoma | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/intracranial-lipoma?lang=us

  Intracranial lipomas are congenital lesions and as such are found at any age when the brain is imaged for other reasons. […] They are usually asymptomatic, and either found incidentally or as a result of investigation of related malformations and their presentation (e.g. epilepsy, hydrocephalus). If symptomatic, patients may present with a range of potential symptoms, including headaches, epilepsy, intellectual disability, and cranial nerve deficits. […] Intracranial lipomas are in most cases asymptomatic, and even when associated with symptomatic malformations (e.g. callosal dysgenesis) they usually require no treatment per se. In fact, attempts at resection have had relatively high morbidity with little benefit due to their vascular characteristics and adhesion to surrounding neural tissue. […] The differential is essentially that of masses which contain fat, and therefore includes: intracranial dermoid, intracranial teratoma, lipomatous transformation of neoplasm.

• #51 Intracranial lipoma | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/intracranial-lipoma?lang=us

  Intracranial lipomas are congenital lesions and as such are found at any age when the brain is imaged for other reasons. […] They are usually asymptomatic, and either found incidentally or as a result of investigation of related malformations and their presentation (e.g. epilepsy, hydrocephalus). If symptomatic, patients may present with a range of potential symptoms, including headaches, epilepsy, intellectual disability, and cranial nerve deficits. […] Intracranial lipomas are in most cases asymptomatic, and even when associated with symptomatic malformations (e.g. callosal dysgenesis) they usually require no treatment per se. In fact, attempts at resection have had relatively high morbidity with little benefit due to their vascular characteristics and adhesion to surrounding neural tissue. […] The differential is essentially that of masses which contain fat, and therefore includes: intracranial dermoid, intracranial teratoma, lipomatous transformation of neoplasm.

• #52 Unusual locations of lipoma: differential diagnosis of head and neck mass

  https://www.racgp.org.au/afp/2014/december/unusual-locations-of-lipoma-differential-diagnosis

  Lipomas are the most common benign neoplasm of mesenchymal origin and may arise in any location where fat is normally present. […] In the head and neck region, where only 13% of lipomas are seen, the posterior neck space is the most common site. […] This article describes two cases of lipoma that were unusually located in the parotid gland and in the sternocleidomastoid muscle (SCM). […] Intraglandular lipoma of the parotid gland should be included as a rare possibility in the differential diagnosis of tumours involving the parotid gland. […] Also, intramuscular lipoma of SCM is rare and should not be overlooked in the differential diagnosis. […] A thorough preoperative clinical, radiological and cytological examination should be performed to prevent recurrences due to incomplete removal of the tumour.

• #53 Unusual locations of lipoma: differential diagnosis of head and neck mass

  https://www.racgp.org.au/afp/2014/december/unusual-locations-of-lipoma-differential-diagnosis

  Lipomas are the most common benign neoplasm of mesenchymal origin and may arise in any location where fat is normally present. […] In the head and neck region, where only 13% of lipomas are seen, the posterior neck space is the most common site. […] This article describes two cases of lipoma that were unusually located in the parotid gland and in the sternocleidomastoid muscle (SCM). […] Intraglandular lipoma of the parotid gland should be included as a rare possibility in the differential diagnosis of tumours involving the parotid gland. […] Also, intramuscular lipoma of SCM is rare and should not be overlooked in the differential diagnosis. […] A thorough preoperative clinical, radiological and cytological examination should be performed to prevent recurrences due to incomplete removal of the tumour.

• #54 Atypical Sites of the Lipoma on the Hand and Fingers: Clinical and Imaging Features and Surgical Outcomes

  https://www.mdpi.com/2075-4418/12/10/2286

  Lipomas are the most frequent benign soft tissue tumor that are rarely found in the hand and are exceptionally rare on the fingers. […] The diagnosis was made by clinical and imaging examinations. […] Surgical treatment was established based on symptoms of pain, paresthesias, functional impairment, or aesthetic concerns. […] Lipomas in the palm and fingers are rare entities (with more men affected), and surgical treatment consists of complete removal of the tumor and providing definitive healing. […] Despite their rarity, clinicians should consider lipomas when making differential diagnoses of soft tissue tumors of the hand. […] The aim of this article is to present the largest series of 27 cases of hand lipomas in the literature (15 cases of the palm, 9 cases of the fingers, and 3 cases of the wrist).

• #55 Atypical Sites of the Lipoma on the Hand and Fingers: Clinical and Imaging Features and Surgical Outcomes

  https://www.mdpi.com/2075-4418/12/10/2286

  Clinical features and diagnostic and surgical outcomes are analyzed and discussed. […] The diagnosis was made by clinical examination, using palpation to determine the consistency and mobility of the lesion and whether the pain was spontaneous or induced by palpation. […] Clinical examination makes the diagnosis of lipoma in approximately 85% of cases. […] Radiological examination can confirm the diagnosis in approximately 70% of cases. […] Most often, the combination of a clinical examination with radiological and ultrasound examinations leads to a diagnosis of lipoma. […] Surgical excision is the mainstay of treatment for lipomas, regardless of their location and size. […] Surgical treatment of smaller lipomas is indicated to avoid complications due to tumor growth (nerve compressions, carpal tunnel syndrome, and sensitivity disorders).

• #56 Parosteal lipoma of humerus with a medical history of 24 years: a case report – Lu – Annals of Joint

  https://aoj.amegroups.org/article/view/6104/html

  Parosteal lipoma is an extremely rare benign tumor, responsible for less than 0.1% of primary bone neoplasms and 0.3% of all lipomas, which mainly constitutes of mature adipose tissue with a bony component. […] The tumor is known to be related with underlying bony changes including focal cortical hyperostosis, pressure erosion of the underlying bone, and bowing malformation. […] In conclusion, orthopedic surgeons should bear the diagnosis of parosteal lipoma in mind, thus providing appropriate treatment. Surgery is usually ideal treatment, which requires that any periosteal involvement is removed completely. […] Parosteal lipomas are benign with an excellent prognosis. Surgery, which is ideal treatment, requires particular attention to ensure that any periosteal involvement is removed completely. For purpose of providing suitable treatment, parosteal lipoma should be incorporated in the differential diagnosis of soft tissue tumors.

• #57 Parosteal lipoma of humerus with a medical history of 24 years: a case report – Lu – Annals of Joint

  https://aoj.amegroups.org/article/view/6104/html

  Parosteal lipoma is an extremely rare benign tumor, responsible for less than 0.1% of primary bone neoplasms and 0.3% of all lipomas, which mainly constitutes of mature adipose tissue with a bony component. […] The tumor is known to be related with underlying bony changes including focal cortical hyperostosis, pressure erosion of the underlying bone, and bowing malformation. […] In conclusion, orthopedic surgeons should bear the diagnosis of parosteal lipoma in mind, thus providing appropriate treatment. Surgery is usually ideal treatment, which requires that any periosteal involvement is removed completely. […] Parosteal lipomas are benign with an excellent prognosis. Surgery, which is ideal treatment, requires particular attention to ensure that any periosteal involvement is removed completely. For purpose of providing suitable treatment, parosteal lipoma should be incorporated in the differential diagnosis of soft tissue tumors.

• #58 Parosteal lipoma of humerus with a medical history of 24 years: a case report – Lu – Annals of Joint

  https://aoj.amegroups.org/article/view/6104/html

  Parosteal lipoma is an extremely rare benign tumor, responsible for less than 0.1% of primary bone neoplasms and 0.3% of all lipomas, which mainly constitutes of mature adipose tissue with a bony component. […] The tumor is known to be related with underlying bony changes including focal cortical hyperostosis, pressure erosion of the underlying bone, and bowing malformation. […] In conclusion, orthopedic surgeons should bear the diagnosis of parosteal lipoma in mind, thus providing appropriate treatment. Surgery is usually ideal treatment, which requires that any periosteal involvement is removed completely. […] Parosteal lipomas are benign with an excellent prognosis. Surgery, which is ideal treatment, requires particular attention to ensure that any periosteal involvement is removed completely. For purpose of providing suitable treatment, parosteal lipoma should be incorporated in the differential diagnosis of soft tissue tumors.

• #59 Ossifying lipoma: literature review and analysis of radiological

  https://www.openaccessjournals.com/articles/ossifying-lipoma-literature-review-and-analysis-of-radiological-imaging-12583.html

  Lipomas are benign tumors consisting primarily of mature adipocytes. Imaging is important in distinguishing benign ossifying lipoma from more aggressive tumors such as well-differentiated liposarcomas. Early diagnosis of ossifying lipoma and understanding of its benign etiology prevent unwarranted medical intervention such as biopsies and surgical resection, as well as decrease patient anxiety. […] Histological examination is often the most useful tool in making a definitive diagnosis of ossifying lipoma. […] Surgical excision is often the treatment for ossifying lipoma. […] The prognosis for ossifying lipomas is the same as that of conventional lipomas, but due to the scarcity of clinical knowledge about ossifying lipomas, patients should receive long-term follow-up. […] This literature review found no reports of recurrence of ossifying lipoma.

• #60 Ossifying lipoma: literature review and analysis of radiological

  https://www.openaccessjournals.com/articles/ossifying-lipoma-literature-review-and-analysis-of-radiological-imaging-12583.html

  Imaging is important in distinguishing benign ossifying lipoma from more aggressive tumors such as well-differentiated liposarcomas. Ossifying lipomas maintain a stable size and show maturing ossification over time, consistent with a long-standing indolent process. […] Early diagnosis of ossifying lipoma and understanding of its benign etiology prevent unwarranted medical intervention such as biopsies and surgical resection.

• #61 Lipomas: Practice Essentials, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/191233-overview

  Treatment consists of complete excision. No contraindications for removal exist, unless the patient is unfit for surgery or the anatomic location makes removal unfeasible. Benign lipomas are simply „shelled out,” with complete removal of the capsule in an extracapsular plane; however, this is an inadequate operation for a liposarcoma. (See Treatment.) Nonoperative (endoscopic) therapy may be employed for some lipomas of the gastrointestinal (GI) tract. Liposuction is an alternative in some cases. Specific therapy depends on the location of the tumor. […] The outcome and prognosis are excellent for benign lipomas. Recurrence is uncommon but may develop if the excision was incomplete.

• #62 Lipoma – Wikipedia

  https://en.wikipedia.org/wiki/Lipoma

  A lipoma is a benign tumor made of fat tissue. They are generally soft to the touch, movable, and painless. Diagnosis is typically based on a physical exam. Occasionally medical imaging or tissue biopsy is used to confirm the diagnosis. […] Treatment is typically by observation or surgical removal. Rarely, the condition may recur following removal, but this can generally be managed with repeat surgery. […] Lipomas are normally removed by simple excision. The removal can often be done under local anesthetic and takes less than 30 minutes. This cures the great majority of cases, with about 12% of lipomas recurring after excision. […] A physical exam is typically the easiest way to diagnose it. Rarely, a tissue biopsy or imaging may be required. The imaging modality of choice is magnetic resonance imaging (MRI) because it has superior sensitivity of distinguishing it from liposarcoma as well as mapping the surrounding anatomy.

• #63 Lipomas: Practice Essentials, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/191233-overview

  Treatment consists of complete excision. No contraindications for removal exist, unless the patient is unfit for surgery or the anatomic location makes removal unfeasible. Benign lipomas are simply „shelled out,” with complete removal of the capsule in an extracapsular plane; however, this is an inadequate operation for a liposarcoma. (See Treatment.) Nonoperative (endoscopic) therapy may be employed for some lipomas of the gastrointestinal (GI) tract. Liposuction is an alternative in some cases. Specific therapy depends on the location of the tumor. […] The outcome and prognosis are excellent for benign lipomas. Recurrence is uncommon but may develop if the excision was incomplete.

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