Materiały źródłowe

• #1 Breast cancer: Epidemiology, risk factors and screening

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10774137/

  The epidemiology of breast cancer has been deeply and constantly investigated over the decades. Understanding the epidemiological characteristics of breast cancer including its incidence, prevalence, and mortality across different demographic and geographic aspects, as well as identifying the risk factors, could facilitate the development of proper public health policies. Screening is a key part of the overall management of breast cancer, which can detect breast cancer at an early stage, thereby reducing the associated mortality dramatically. […] In 2020, female breast cancer became the most commonly diagnosed cancer globally for the first time, with an estimated 2.26 million new cases reported. The latest global statistics showed that breast cancer was the leading cause of cancer-related mortality among women, ranking fifth in overall cancer deaths. […] The mortality rate of breast cancer also fluctuated over the past few decades. The latest global statistics showed that breast cancer was the leading cause of cancer-related mortality among women, ranking fifth in overall cancer deaths.

• #2 The Epidemiology of Breast Cancer – Breast Cancer – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK583819/

  As of 2020, breast cancer has become the most diagnosed cancer globally, overtaking lung and prostate cancers. Breast cancer incidence is increasing globally with cases in the United States expected to reach 364,000 in the year 2040. […] Developed countries have the highest incidence of breast cancer. Mortality rates vary widely from global region to region but are highest in socio-economically low areas, reflecting a lack of access to early screening and timely treatment. […] This chapter aims to provide a global epidemiological overview of breast cancer incidence and mortality. […] The incidence of BC has been growing by amounts that depend in part on a country’s developmental index and the availability and utilization of BC screening methods such as self-breast examinations and mammography.

• #3

  https://www.who.int/news-room/fact-sheets/detail/breast-cancer

  Breast cancer caused 670 000 deaths globally in 2022. […] Breast cancer occurs in every country of the world. […] In 2022, there were 2.3 million women diagnosed with breast cancer and 670 000 deaths globally. Breast cancer occurs in every country of the world in women at any age after puberty but with increasing rates in later life. […] Female gender is the strongest breast cancer risk factor. […] Approximately 99% of breast cancers occur in women and 0.51% of breast cancers occur in men. […] Certain factors increase the risk of breast cancer including increasing age, obesity, harmful use of alcohol, family history of breast cancer, history of radiation exposure, reproductive history (such as age that menstrual periods began and age at first pregnancy), tobacco use and postmenopausal hormone therapy.

• #4 Breast cancer: Epidemiology, risk factors and screening

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10774137/

  The epidemiology of breast cancer has been deeply and constantly investigated over the decades. Understanding the epidemiological characteristics of breast cancer including its incidence, prevalence, and mortality across different demographic and geographic aspects, as well as identifying the risk factors, could facilitate the development of proper public health policies. Screening is a key part of the overall management of breast cancer, which can detect breast cancer at an early stage, thereby reducing the associated mortality dramatically. […] In 2020, female breast cancer became the most commonly diagnosed cancer globally for the first time, with an estimated 2.26 million new cases reported. The latest global statistics showed that breast cancer was the leading cause of cancer-related mortality among women, ranking fifth in overall cancer deaths. […] The mortality rate of breast cancer also fluctuated over the past few decades. The latest global statistics showed that breast cancer was the leading cause of cancer-related mortality among women, ranking fifth in overall cancer deaths.

• #5

  https://www.who.int/news-room/fact-sheets/detail/breast-cancer

  Breast cancer caused 670 000 deaths globally in 2022. […] Breast cancer occurs in every country of the world. […] In 2022, there were 2.3 million women diagnosed with breast cancer and 670 000 deaths globally. Breast cancer occurs in every country of the world in women at any age after puberty but with increasing rates in later life. […] Female gender is the strongest breast cancer risk factor. […] Approximately 99% of breast cancers occur in women and 0.51% of breast cancers occur in men. […] Certain factors increase the risk of breast cancer including increasing age, obesity, harmful use of alcohol, family history of breast cancer, history of radiation exposure, reproductive history (such as age that menstrual periods began and age at first pregnancy), tobacco use and postmenopausal hormone therapy.

• #6 Epidemiology of breast cancer – Wikipedia

  https://en.wikipedia.org/wiki/Epidemiology_of_breast_cancer

  Worldwide, breast cancer is the most common invasive cancer in women. Breast cancer comprises 22.9% of invasive cancers in women and 16% of all female cancers. […] In 2008, breast cancer caused 458,503 deaths worldwide, which is 13.7% of cancer deaths in women and 6.0% of all cancer deaths for men and women together. […] The number of cases worldwide has significantly increased since the 1970s, a phenomenon partly attributed to the modern lifestyles. […] Breast cancer is strongly related to age, with only 5% of all breast cancers occurring in women under 40 years old. […] The incidence of breast cancer varies greatly around the world: it is lowest in less-developed countries and greatest in the more-developed countries. […] The lifetime risk for breast cancer in the United States is usually given as about 1 in 8 (12%) of women by age 95, with a 1 in 35 (3%) chance of dying from breast cancer.

• #7 ONCOLOGIE | Epidemiology of Breast Cancer

  https://www.techscience.com/oncologie/v24n4/51031

  All over the world, the most common malignancy in women is breast cancer. Breast cancer is also a significant factor of death in women. In 2020, approximately 2.3 million cases of breast cancer were newly diagnosed in women globally, and approximately 685,000 people died. Breast cancer incidence varies by region around the world, but it is all increasing. According to the current morbidity and mortality trend of breast cancer, it is estimated that by 2030, the number of incidence and deaths of breast cancer will reach 2.64 million and 1.7 million, respectively. The age-standardized incidence rate was 66.4/100,000 in developed countries and 27.3/100,000 in developing countries. The incidence of breast cancer in the world is increasing rapidly, and the incidence rate has increased by 57.8% in the past 30 years, and the rate of increase is 0.5% per year.

• #8 The Epidemiology of Breast Cancer – Breast Cancer – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK583819/

  As of 2020, breast cancer has become the most diagnosed cancer globally, overtaking lung and prostate cancers. Breast cancer incidence is increasing globally with cases in the United States expected to reach 364,000 in the year 2040. […] Developed countries have the highest incidence of breast cancer. Mortality rates vary widely from global region to region but are highest in socio-economically low areas, reflecting a lack of access to early screening and timely treatment. […] This chapter aims to provide a global epidemiological overview of breast cancer incidence and mortality. […] The incidence of BC has been growing by amounts that depend in part on a country’s developmental index and the availability and utilization of BC screening methods such as self-breast examinations and mammography.

• #9 ONCOLOGIE | Epidemiology of Breast Cancer

  https://www.techscience.com/oncologie/v24n4/51031

  All over the world, the most common malignancy in women is breast cancer. Breast cancer is also a significant factor of death in women. In 2020, approximately 2.3 million cases of breast cancer were newly diagnosed in women globally, and approximately 685,000 people died. Breast cancer incidence varies by region around the world, but it is all increasing. According to the current morbidity and mortality trend of breast cancer, it is estimated that by 2030, the number of incidence and deaths of breast cancer will reach 2.64 million and 1.7 million, respectively. The age-standardized incidence rate was 66.4/100,000 in developed countries and 27.3/100,000 in developing countries. The incidence of breast cancer in the world is increasing rapidly, and the incidence rate has increased by 57.8% in the past 30 years, and the rate of increase is 0.5% per year.

• #10

  https://www.who.int/news-room/fact-sheets/detail/breast-cancer

  Family history of breast cancer increases the risk of breast cancer, but most women diagnosed with breast cancer do not have a known family history of the disease. […] Certain inherited high penetrance gene mutations greatly increase breast cancer risk, the most dominant being mutations in the genes BRCA1, BRCA2 and PALB-2. […] The objective of the WHO Global Breast Cancer Initiative (GBCI) is to reduce global breast cancer mortality by 2.5% per year, thereby averting 2.5 million breast cancer deaths globally between 2020 and 2040.

• #11 Breast cancer: Epidemiology, risk factors and screening

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10774137/

  Globally, there exist notable variations across different regions and among various ethnicity, often reflecting a complex interplay of genetic, environmental, socioeconomic, and healthcare access factors. It has been observed that countries with a high human development index (HDI) like Northern America, Australia, and Northern and Western Europe, tend to have a higher incidence of breast cancer compared to those with a lower HDI. […] The stage at diagnosis of breast cancer tends to be later in countries like those in sub-Saharan Africa, as indicated by a meta-analysis. […] Breast cancer screening, which involves various methods, is part of a secondary prevention strategy for breast cancer, facilitating early detection and treatment. Though the screening is recommended by different guidelines of breast cancer, it is important to balance the benefits and harms of screening and to select suitable screening modality for each patient.

• #12 Breast cancer: Epidemiology, risk factors and screening

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10774137/

  Globally, there exist notable variations across different regions and among various ethnicity, often reflecting a complex interplay of genetic, environmental, socioeconomic, and healthcare access factors. It has been observed that countries with a high human development index (HDI) like Northern America, Australia, and Northern and Western Europe, tend to have a higher incidence of breast cancer compared to those with a lower HDI. […] The stage at diagnosis of breast cancer tends to be later in countries like those in sub-Saharan Africa, as indicated by a meta-analysis. […] Breast cancer screening, which involves various methods, is part of a secondary prevention strategy for breast cancer, facilitating early detection and treatment. Though the screening is recommended by different guidelines of breast cancer, it is important to balance the benefits and harms of screening and to select suitable screening modality for each patient.

• #13 ONCOLOGIE | Epidemiology of Breast Cancer

  https://www.techscience.com/oncologie/v24n4/51031

  All over the world, the most common malignancy in women is breast cancer. Breast cancer is also a significant factor of death in women. In 2020, approximately 2.3 million cases of breast cancer were newly diagnosed in women globally, and approximately 685,000 people died. Breast cancer incidence varies by region around the world, but it is all increasing. According to the current morbidity and mortality trend of breast cancer, it is estimated that by 2030, the number of incidence and deaths of breast cancer will reach 2.64 million and 1.7 million, respectively. The age-standardized incidence rate was 66.4/100,000 in developed countries and 27.3/100,000 in developing countries. The incidence of breast cancer in the world is increasing rapidly, and the incidence rate has increased by 57.8% in the past 30 years, and the rate of increase is 0.5% per year.

• #14 The Epidemiology of Breast Cancer – Breast Cancer – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK583819/

  According to the World Health Organization (WHO), the human development index is measured by a country’s accomplishments in three essential dimensions: health as measured by life expectancy at birth, knowledge as measured by mean and anticipated years of schooling and standard of living or quality of life as measured by gross national income. […] In 2020, BC accounted for nearly 12% of all new cancer cases diagnosed in 7.8 million women worldwide. […] The ASIR was highest in countries with a very high human development index (75.6 cases/100,000). […] Early detection of BC is inversely proportional to BC mortality; thus, screening and increased individual awareness of BC leads to better outcomes. […] Nevertheless, recently BC has become the fifth leading cause of mortality and the leading cause of death from cancer among women worldwide.

• #15 Breast cancer in the world: Incidence and mortality

  https://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0036-36342011000500005

  The aim of this paper is to describe the burden of breast cancer in the world, as the now most common cancer in women in the globe. Here a descriptive pattern based on information available in IARC and WHO databases describing estimated age-specific incidence is presented, both for incidence and mortality. […] Breast cancer is the most frequent type of cancer in women and it was estimated that 1.38 million new breast cancer cases were diagnosed in 2008 (23% of all cancers); it ranks second overall (10.9% of all cancers). It is the most common cancer both in developed and developing regions with around 690 000 new cases estimated in each of them (population ratio 1:4). […] Incidence rates vary from 19.3 per 100 000 women in Eastern Africa to 89.9 per 100 000 women in Western Europe, and are high (more than 80 per 100 000) in developed regions of the world (except Japan) and low (less than 40 per 100 000) in most of the developing regions.

• #16 Epidemiology of breast cancer – Wikipedia

  https://en.wikipedia.org/wiki/Epidemiology_of_breast_cancer

  The United States has the highest annual incidence rates of breast cancer in the world; 128.6 per 100,000 in whites and 112.6 per 100,000 among African Americans. […] In the US, both incidence and death rates for breast cancer have been declining in the last few years. […] The age-standardised incidence rate of breast cancer is 113.4 per 100,000 populations in Wales and there has been a significant increase in the incidence of breast cancer in Wales over the last three decades. […] Breast cancer in less developed countries, such as those in South America, is a major public health issue. […] Breast cancer has the highest incidence among Sub Saharan African women, and has now also the highest mortality rate in many of the countries in the region, before cervical cancer. […] Breast cancer causes 20% of cancer deaths in women and represents 25% of cancers diagnosed.

• #17 Breast cancer statistics | World Cancer Research Fund

  https://www.wcrf.org/preventing-cancer/cancer-statistics/breast-cancer-statistics/

  Breast cancer is the 2nd most common cancer worldwide. […] Breast cancer is the number one cancer in women. There were 2,296,840 new cases of breast cancer in 2022 among women. […] The following table gives the top 5 countries by ASR for breast cancer incidence in women. […] China, the US and India had the highest number of breast cancer cases in 2022. […] India, China and the US had the highest number of deaths from breast cancer in 2022. […] The following table shows the 10 countries with the highest number of breast cancer deaths among women in 2022.

• #18 The Epidemiology of Breast Cancer – Breast Cancer – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK583819/

  In the developing world, women have a 17% higher BC mortality rate due to a lack of defined early screening standards and poor or delayed access to treatment. […] The highest 5-year survival rate (99.1%) in the USA is seen in BC cases with tumors localized to the initial place of origin. […] The 5-year survival rate from 2012 to 2018 was 90.6%. […] According to the American Cancer Society, 43,250 women and 530 men are expected to die from BC in 2022, while the projected 2040 BC mortality is expected to decrease to 30,000 deaths. […] Overall, the incidence of breast cancer has doubled in the last few decades in 60/102 countries, including Argentina, Brazil, and Afghanistan. […] Better organized screening programs, establishment of breast cancer registries, and more widespread use of mammography screening in lower developmental regions of the world can increase early-stage breast cancer diagnosis, reduce breast cancer-related mortality, and help reduce future global breast cancer burden.

• #19 Breast cancer: Epidemiology, risk factors and screening

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10774137/

  Globally, there exist notable variations across different regions and among various ethnicity, often reflecting a complex interplay of genetic, environmental, socioeconomic, and healthcare access factors. It has been observed that countries with a high human development index (HDI) like Northern America, Australia, and Northern and Western Europe, tend to have a higher incidence of breast cancer compared to those with a lower HDI. […] The stage at diagnosis of breast cancer tends to be later in countries like those in sub-Saharan Africa, as indicated by a meta-analysis. […] Breast cancer screening, which involves various methods, is part of a secondary prevention strategy for breast cancer, facilitating early detection and treatment. Though the screening is recommended by different guidelines of breast cancer, it is important to balance the benefits and harms of screening and to select suitable screening modality for each patient.

• #20 Epidemiology and clinical characteristics of breast cancer in Ethiopia: a systematic review | BMC Cancer | Full Text

  https://bmccancer.biomedcentral.com/articles/10.1186/s12885-024-12822-5

  A country assessment showed that breast cancer is the most common cancer illness in Ethiopia, accounting for 16,133 (20.9%) of all cancer cases and 9,061 (17.5%) of all cancer-related deaths. Approximately 80% of breast cancer cases in sub-Saharan Africa are detected at late stages (stage III or IV), compared to 15% in high-income countries. […] This review summarized the epidemiology, clinical and histological characteristics, and treatment modalities of breast cancer in Ethiopia. Breast cancer incidence is rising, and it accounts for the major cancer burden in the country. There is a need for additional awareness-raising and health education because delayed presentation is a critical problem throughout Ethiopia. For planning and monitoring cancer patterns, comprehensive demographic and clinical data from a population- or facility-based registry are needed.

• #21 Epidemiology of breast cancer – Wikipedia

  https://en.wikipedia.org/wiki/Epidemiology_of_breast_cancer

  The United States has the highest annual incidence rates of breast cancer in the world; 128.6 per 100,000 in whites and 112.6 per 100,000 among African Americans. […] In the US, both incidence and death rates for breast cancer have been declining in the last few years. […] The age-standardised incidence rate of breast cancer is 113.4 per 100,000 populations in Wales and there has been a significant increase in the incidence of breast cancer in Wales over the last three decades. […] Breast cancer in less developed countries, such as those in South America, is a major public health issue. […] Breast cancer has the highest incidence among Sub Saharan African women, and has now also the highest mortality rate in many of the countries in the region, before cervical cancer. […] Breast cancer causes 20% of cancer deaths in women and represents 25% of cancers diagnosed.

• #22 Epidemiology of breast cancer – Wikipedia

  https://en.wikipedia.org/wiki/Epidemiology_of_breast_cancer

  The United States has the highest annual incidence rates of breast cancer in the world; 128.6 per 100,000 in whites and 112.6 per 100,000 among African Americans. […] In the US, both incidence and death rates for breast cancer have been declining in the last few years. […] The age-standardised incidence rate of breast cancer is 113.4 per 100,000 populations in Wales and there has been a significant increase in the incidence of breast cancer in Wales over the last three decades. […] Breast cancer in less developed countries, such as those in South America, is a major public health issue. […] Breast cancer has the highest incidence among Sub Saharan African women, and has now also the highest mortality rate in many of the countries in the region, before cervical cancer. […] Breast cancer causes 20% of cancer deaths in women and represents 25% of cancers diagnosed.

• #23 Epidemiology of breast cancer – Wikipedia

  https://en.wikipedia.org/wiki/Epidemiology_of_breast_cancer

  Many reasons were found to be the source of this disparity, including the fact that breast cancer is diagnosed at later stages in Sub Saharan Africa. […] One of the major challenges in reducing the burden of breast cancer in Sub Saharan Africa remains the lack of National Cancer Control Programs and the lack of human as well as financial resources.

• #24 Female Breast Cancer — Cancer Stat Facts

  https://seer.cancer.gov/statfacts/html/breast.html

  Estimated New Cases in 2025 316,950 […] % of All New Cancer Cases 15.5% […] Estimated Deaths in 2025 42,170 […] % of All Cancer Deaths 6.8% […] The rate of new cases of female breast cancer was 130.8 per 100,000 women per year. The death rate was 19.2 per 100,000 women per year. These rates are age-adjusted and based on 2018-2022 cases and 2019-2023 deaths. […] Approximately 13.0 percent of women will be diagnosed with female breast cancer at some point during their lifetime, based on 2018-2021 data, excluding 2020 due to COVID. […] In 2022, there were an estimated 4,091,181 women living with female breast cancer in the United States. […] Female breast cancer represents 15.5% of all new cancer cases in the U.S. […] In 2025, it is estimated that there will be 316,950 new cases of female breast cancer and an estimated 42,170 people will die of this disease.

• #25 Female Breast Cancer — Cancer Stat Facts

  https://seer.cancer.gov/statfacts/html/breast.html

  Estimated New Cases in 2025 316,950 […] % of All New Cancer Cases 15.5% […] Estimated Deaths in 2025 42,170 […] % of All Cancer Deaths 6.8% […] The rate of new cases of female breast cancer was 130.8 per 100,000 women per year. The death rate was 19.2 per 100,000 women per year. These rates are age-adjusted and based on 2018-2022 cases and 2019-2023 deaths. […] Approximately 13.0 percent of women will be diagnosed with female breast cancer at some point during their lifetime, based on 2018-2021 data, excluding 2020 due to COVID. […] In 2022, there were an estimated 4,091,181 women living with female breast cancer in the United States. […] Female breast cancer represents 15.5% of all new cancer cases in the U.S. […] In 2025, it is estimated that there will be 316,950 new cases of female breast cancer and an estimated 42,170 people will die of this disease.

• #26 Breast Cancer Facts & Stats 2024 – Incidence, Age, Survival, & More

  https://www.nationalbreastcancer.org/breast-cancer-facts/

  1 in 8 women in the United States will be diagnosed with breast cancer in her lifetime. In 2025, an estimated 316,950 women and 2,800 men will be diagnosed with invasive breast cancer, and an additional 59,080 new cases of non-invasive (in situ) breast cancer will be diagnosed. […] When caught in its earliest, localized stages, the 5-year relative survival rate is 99%. Advances in early detection and treatment methods have significantly increased breast cancer survival rates in recent years, and there are currently over 4 million breast cancer survivors in the United States. […] The early detection of breast cancer through annual mammography and other breast exams is the best defense against receiving a late-stage breast cancer diagnosis. Generally speaking, the earlier the cancer is detected, the greater the likelihood of a successful outcome.

• #27 Breast Cancer Statistics | Breast Cancer | CDC

  https://www.cdc.gov/breast-cancer/statistics/index.html

  Breast cancer is the second most common cancer among women in the United States. Breast cancer is the second leading cause of cancer death among women in the United States. For non-Hispanic Black women and Hispanic women, breast cancer is the leading cause of cancer death. […] The Breast Cancer Stat Bite provides an overview of incidence, deaths, stage distribution, and 5-year relative survival. […] Cancer Statistics At a Glance: See rates or numbers of new breast cancers or breast cancer deaths for the entire United States and individual states. […] Cancers by Age, Sex, Race, and Ethnicity: See rates or numbers of new breast cancers or breast cancer deaths by race and ethnicity and age group. […] Trends: See how the rates of new breast cancers or breast cancer deaths changed over time for the entire United States and individual states.

• #28 Female Breast Cancer — Cancer Stat Facts

  https://seer.cancer.gov/statfacts/html/breast.html

  The rate of new cases of female breast cancer was 130.8 per 100,000 women per year based on 2018-2022 cases, age-adjusted. […] Overall, female breast cancer survival is good. However, women who are diagnosed at an advanced age may be more likely than younger women to die of the disease. Female breast cancer is the fourth leading cause of cancer death in the United States. The death rate was 19.2 per 100,000 women per year based on 2019-2023, age-adjusted. […] The percent of female breast cancer deaths is highest among women aged 65-74. […] Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments. […] Using statistical models for analysis, age-adjusted rates for new female breast cancer cases have been rising on average 0.6% each year over 2013-2022. Age-adjusted death rates have been falling on average 1.2% each year over 2014-2023.

• #29 Female Breast Cancer — Cancer Stat Facts

  https://seer.cancer.gov/statfacts/html/breast.html

  Estimated New Cases in 2025 316,950 […] % of All New Cancer Cases 15.5% […] Estimated Deaths in 2025 42,170 […] % of All Cancer Deaths 6.8% […] The rate of new cases of female breast cancer was 130.8 per 100,000 women per year. The death rate was 19.2 per 100,000 women per year. These rates are age-adjusted and based on 2018-2022 cases and 2019-2023 deaths. […] Approximately 13.0 percent of women will be diagnosed with female breast cancer at some point during their lifetime, based on 2018-2021 data, excluding 2020 due to COVID. […] In 2022, there were an estimated 4,091,181 women living with female breast cancer in the United States. […] Female breast cancer represents 15.5% of all new cancer cases in the U.S. […] In 2025, it is estimated that there will be 316,950 new cases of female breast cancer and an estimated 42,170 people will die of this disease.

• #30 Approach to the patient following treatment for breast cancer – UpToDate

  https://www.uptodate.com/contents/approach-to-the-patient-following-treatment-for-breast-cancer

  Recommendations for post-treatment surveillance after primary therapy of breast cancer will be reviewed here. Detailed discussions of prognosis, the patterns of relapse (ie, locoregional recurrence, second primary breast tumor, metastatic disease), and long-term complications of breast cancer therapy are presented separately. […] By this definition, there are more than four million breast cancer survivors in the United States, including over 150,000 living with overt metastatic disease.

• #31 Female Breast Cancer — Cancer Stat Facts

  https://seer.cancer.gov/statfacts/html/breast.html

  Estimated New Cases in 2025 316,950 […] % of All New Cancer Cases 15.5% […] Estimated Deaths in 2025 42,170 […] % of All Cancer Deaths 6.8% […] The rate of new cases of female breast cancer was 130.8 per 100,000 women per year. The death rate was 19.2 per 100,000 women per year. These rates are age-adjusted and based on 2018-2022 cases and 2019-2023 deaths. […] Approximately 13.0 percent of women will be diagnosed with female breast cancer at some point during their lifetime, based on 2018-2021 data, excluding 2020 due to COVID. […] In 2022, there were an estimated 4,091,181 women living with female breast cancer in the United States. […] Female breast cancer represents 15.5% of all new cancer cases in the U.S. […] In 2025, it is estimated that there will be 316,950 new cases of female breast cancer and an estimated 42,170 people will die of this disease.

• #32 Epidemiology of breast cancer – Wikipedia

  https://en.wikipedia.org/wiki/Epidemiology_of_breast_cancer

  Worldwide, breast cancer is the most common invasive cancer in women. Breast cancer comprises 22.9% of invasive cancers in women and 16% of all female cancers. […] In 2008, breast cancer caused 458,503 deaths worldwide, which is 13.7% of cancer deaths in women and 6.0% of all cancer deaths for men and women together. […] The number of cases worldwide has significantly increased since the 1970s, a phenomenon partly attributed to the modern lifestyles. […] Breast cancer is strongly related to age, with only 5% of all breast cancers occurring in women under 40 years old. […] The incidence of breast cancer varies greatly around the world: it is lowest in less-developed countries and greatest in the more-developed countries. […] The lifetime risk for breast cancer in the United States is usually given as about 1 in 8 (12%) of women by age 95, with a 1 in 35 (3%) chance of dying from breast cancer.

• #33 Female Breast Cancer — Cancer Stat Facts

  https://seer.cancer.gov/statfacts/html/breast.html

  The rate of new cases of female breast cancer was 130.8 per 100,000 women per year based on 2018-2022 cases, age-adjusted. […] Overall, female breast cancer survival is good. However, women who are diagnosed at an advanced age may be more likely than younger women to die of the disease. Female breast cancer is the fourth leading cause of cancer death in the United States. The death rate was 19.2 per 100,000 women per year based on 2019-2023, age-adjusted. […] The percent of female breast cancer deaths is highest among women aged 65-74. […] Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments. […] Using statistical models for analysis, age-adjusted rates for new female breast cancer cases have been rising on average 0.6% each year over 2013-2022. Age-adjusted death rates have been falling on average 1.2% each year over 2014-2023.

• #34 Breast Cancer Statistics And Resources | Breast Cancer Research Foundation

  https://www.bcrf.org/breast-cancer-statistics-and-resources/

  Breast cancer is the most common cancer among American women after nonmelanoma skin cancer. […] In 2025, an estimated 319,750 people will be diagnosed with breast cancer in the U.S. […] In 2025, an estimated 316,950 women will be diagnosed with breast cancer in the U.S., making it the most common cancer in American women. Every two minutes a woman in the U.S. is diagnosed with the disease. […] In 2025, an estimated 42,680 people (42,170 women and 510 men) will die from the disease. […] The five- and 10-year relative survival rates for women with invasive breast cancer are 91 percent and 84 percent, respectively. […] The overall five-year relative survival rate is 99 percent for localized disease, 86 percent for regional disease, and 30 percent for distant-stage disease. […] Since 1975, the breast cancer five-year relative survival rate has increased significantly for both black and white women. While a substantial gap remains, especially for late-stage diagnoses, the racial disparity seems to be narrowing. In the most recent period, the five-year relative survival rate was 83 percent for black women and 92 percent for white women.

• #35 Breast Cancer – Europa Donna

  https://www.europadonna.org/breast-cancer/

  Breast cancer is the most commonly diagnosed cancer in women, and accounts for 1 in 4 annual cancer cases worldwide*. […] Breast cancer is the most common cancer in women in the WHO Europe region with an estimated incidence of 604,900 in 2022*. […] Incidence in the EU-27 in 2022 was estimated to be 375,000*. […] 1 in 11 women in the EU-27 will develop breast cancer before the age of 74*. […] An estimated 20% of breast cancer cases in Europe occur in women when they are younger than 50 years old*. […] Breast cancer therefore affects many women during their years dedicated to working and raising a family. […] Breast cancer is the leading cause of cancer death in women worldwide accounting for 1 in 6 cancer deaths*. […] Estimated number of women who died from breast cancer in 2022* WHO Europe region: 160,000 EU-27 member states: 95,800. […] European women aged 15 and older diagnosed with breast cancer between 2000 and 2007 had an estimated 5-year relative survival rate of 83%*. […] Estimated numbers and age-standardised breast cancer incidence and mortality rates** in women per 100,000 in 2022*.

• #36 Breast Cancer – Europa Donna

  https://www.europadonna.org/breast-cancer/

  Breast cancer is the most commonly diagnosed cancer in women, and accounts for 1 in 4 annual cancer cases worldwide*. […] Breast cancer is the most common cancer in women in the WHO Europe region with an estimated incidence of 604,900 in 2022*. […] Incidence in the EU-27 in 2022 was estimated to be 375,000*. […] 1 in 11 women in the EU-27 will develop breast cancer before the age of 74*. […] An estimated 20% of breast cancer cases in Europe occur in women when they are younger than 50 years old*. […] Breast cancer therefore affects many women during their years dedicated to working and raising a family. […] Breast cancer is the leading cause of cancer death in women worldwide accounting for 1 in 6 cancer deaths*. […] Estimated number of women who died from breast cancer in 2022* WHO Europe region: 160,000 EU-27 member states: 95,800. […] European women aged 15 and older diagnosed with breast cancer between 2000 and 2007 had an estimated 5-year relative survival rate of 83%*. […] Estimated numbers and age-standardised breast cancer incidence and mortality rates** in women per 100,000 in 2022*.

• #37 Breast Cancer – Europa Donna

  https://www.europadonna.org/breast-cancer/

  Breast cancer is the most commonly diagnosed cancer in women, and accounts for 1 in 4 annual cancer cases worldwide*. […] Breast cancer is the most common cancer in women in the WHO Europe region with an estimated incidence of 604,900 in 2022*. […] Incidence in the EU-27 in 2022 was estimated to be 375,000*. […] 1 in 11 women in the EU-27 will develop breast cancer before the age of 74*. […] An estimated 20% of breast cancer cases in Europe occur in women when they are younger than 50 years old*. […] Breast cancer therefore affects many women during their years dedicated to working and raising a family. […] Breast cancer is the leading cause of cancer death in women worldwide accounting for 1 in 6 cancer deaths*. […] Estimated number of women who died from breast cancer in 2022* WHO Europe region: 160,000 EU-27 member states: 95,800. […] European women aged 15 and older diagnosed with breast cancer between 2000 and 2007 had an estimated 5-year relative survival rate of 83%*. […] Estimated numbers and age-standardised breast cancer incidence and mortality rates** in women per 100,000 in 2022*.

• #38 Breast Cancer Statistics in Australia | NBCFNational Breast Cancer Foundation logoNational Breast Cancer Foundation logo

  https://nbcf.org.au/about-breast-cancer/breast-cancer-stats/

  Breast cancer is the second most commonly diagnosed cancer in Australia and the most common cancer among females. […] Everyday 58 people in Australia will be diagnosed with breast cancer. That equates to over 21,000 people in Australia being diagnosed with breast cancer each year. […] 1 in 7 women and 1 in 550 men are diagnosed with breast cancer in their lifetime. […] Around 1,000 young women aged under 40 are diagnosed with breast cancer each year, equivalent to about 3 young women each day. […] Every year over 3,300 people in Australian (including 33 men) will die from breast cancer. That’s 9 Australians a day dying from the disease. […] In the last 10 years, breast cancer diagnosis have increased by 24%. […] Since the National Breast Cancer Foundation (NBCF) started funding in 1994, the death rate from breast cancer in Australia has reduced by over 40% thanks in large part to research in prevention, early detection and new and improved breast cancer treatments.

• #39 Breast Cancer Statistics in Australia | NBCFNational Breast Cancer Foundation logoNational Breast Cancer Foundation logo

  https://nbcf.org.au/about-breast-cancer/breast-cancer-stats/

  Breast cancer is the second most commonly diagnosed cancer in Australia and the most common cancer among females. […] Everyday 58 people in Australia will be diagnosed with breast cancer. That equates to over 21,000 people in Australia being diagnosed with breast cancer each year. […] 1 in 7 women and 1 in 550 men are diagnosed with breast cancer in their lifetime. […] Around 1,000 young women aged under 40 are diagnosed with breast cancer each year, equivalent to about 3 young women each day. […] Every year over 3,300 people in Australian (including 33 men) will die from breast cancer. That’s 9 Australians a day dying from the disease. […] In the last 10 years, breast cancer diagnosis have increased by 24%. […] Since the National Breast Cancer Foundation (NBCF) started funding in 1994, the death rate from breast cancer in Australia has reduced by over 40% thanks in large part to research in prevention, early detection and new and improved breast cancer treatments.

• #40 Breast Cancer Statistics in Australia | NBCFNational Breast Cancer Foundation logoNational Breast Cancer Foundation logo

  https://nbcf.org.au/about-breast-cancer/breast-cancer-stats/

  The risk of a woman being diagnosed with breast cancer in her lifetime is 1 in 7. The risk of a man being diagnosed with breast cancer in their lifetime is 1 in 550. […] The majority of breast cancer cases, about 80%, occur in women over the age of 50. But breast cancer still occurs in young women, with close to 1,000 women under the age of 40 projected to be diagnosed with the disease. […] The relative five-year survival rate for breast cancer is 92%. […] The five-year survival rate for Stage 1 (early) breast cancer is, on average, 100% and Stage 2 is 95%. For locally advanced cancers (known as Stage 3) the survival rate is 81%, while the five-year survival rate for Stage 4 (metastatic breast cancer) is significantly lower at 32%. […] The incidence (the number of new cases) of breast cancer has risen dramatically over the past 30 years, rising from about 9,832 new cases a year in 1994, to over 21,000 new cases a year in 2024.

• #41 Breast cancer statistics | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/breast/statistics

  Breast cancer is the most common cancer among Canadian women (excluding non-melanoma skin cancers). It is the 2nd leading cause of death from cancer in Canadian women. Breast cancer can also occur in men, but it is not common. […] To provide the most current cancer statistics, statistical methods are used to estimate the number of new cancer cases and deaths until actual data become available. […] It is estimated that in 2024: 30,500 Canadian women will be diagnosed with breast cancer. This represents 25% of all new cancer cases in women in 2024. 5,500 Canadian women will die from breast cancer. This represents 13% of all cancer deaths in women in 2024. On average, 84 Canadian women will be diagnosed with breast cancer every day. On average, 15 Canadian women will die from breast cancer every day. 290 Canadian men will be diagnosed with breast cancer and 60 will die from breast cancer.

• #42 Breast cancer statistics | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/breast/statistics

  Breast cancer is the most common cancer among Canadian women (excluding non-melanoma skin cancers). It is the 2nd leading cause of death from cancer in Canadian women. Breast cancer can also occur in men, but it is not common. […] To provide the most current cancer statistics, statistical methods are used to estimate the number of new cancer cases and deaths until actual data become available. […] It is estimated that in 2024: 30,500 Canadian women will be diagnosed with breast cancer. This represents 25% of all new cancer cases in women in 2024. 5,500 Canadian women will die from breast cancer. This represents 13% of all cancer deaths in women in 2024. On average, 84 Canadian women will be diagnosed with breast cancer every day. On average, 15 Canadian women will die from breast cancer every day. 290 Canadian men will be diagnosed with breast cancer and 60 will die from breast cancer.

• #43 Breast cancer statistics | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/breast/statistics

  The breast cancer death rate peaked in 1986 and has been declining since. This reduction in death rates likely reflects the impact of screening and improvements in treatment for breast cancer. […] It is estimated that about 1 in 8 Canadian women will develop breast cancer during their lifetime and 1 in 36 will die from it.

• #44 Krebs – Breast cancer

  https://www.krebsdaten.de/Krebs/EN/Content/Cancer_sites/Breast_cancer/breast_cancer_node.html

  With approximately 74,500 annual incident cases, breast cancer is by far the most common cancer in women. […] Based on current incidence rates, about one in eight women is expected to develop breast cancer over the course of a lifetime. Almost one out of six affected women are below 55 years of age at diagnosis. […] Following the introduction of mammography screening between 2005 and 2009, the rates of new cases show a typical trend with a significant increase at the beginning of the program and a subsequent slow decline. […] Progress in therapy has substantially improved the survival chances of people diagnosed with breast cancer, and this has led to a decrease in mortality rates as well. […] Hormones can influence the risk of disease: Early first and late last menstruation, childlessness or a higher age at first birth are considered risk factors.

• #45 Epidemiology and clinical characteristics of breast cancer in Ethiopia: a systematic review | BMC Cancer | Full Text

  https://bmccancer.biomedcentral.com/articles/10.1186/s12885-024-12822-5

  A country assessment showed that breast cancer is the most common cancer illness in Ethiopia, accounting for 16,133 (20.9%) of all cancer cases and 9,061 (17.5%) of all cancer-related deaths. Approximately 80% of breast cancer cases in sub-Saharan Africa are detected at late stages (stage III or IV), compared to 15% in high-income countries. […] This review summarized the epidemiology, clinical and histological characteristics, and treatment modalities of breast cancer in Ethiopia. Breast cancer incidence is rising, and it accounts for the major cancer burden in the country. There is a need for additional awareness-raising and health education because delayed presentation is a critical problem throughout Ethiopia. For planning and monitoring cancer patterns, comprehensive demographic and clinical data from a population- or facility-based registry are needed.

• #46 Epidemiology and Histopathology of Breast Cancer in Iran versus Other Middle Eastern Countries

  https://mejc.sums.ac.ir/article_42130.html

  Background: Breast cancer is the most prevalent cancer among females worldwide. […] Overall, breast cancer was the most common cancer in Iran. The age-standardized rate for breast cancer was 33.21 per 100,000 according to the latest national databases. The mortality rate for breast cancer has not changed in the past 30 years in Iran. The age-standardized rate for mortality was 14.2 per 100,000 with a mean age of 49.84 years. The most common cancer in Iran is invasive ductal carcinoma. […] Our study shows that epidemiology and histopathology of cancer is different with other neighborhood countries and is multi-dimension and needs multicenter involvement from government authorities, clinicians and scientists.

• #47

  https://www.who.int/news-room/fact-sheets/detail/breast-cancer

  Breast cancer caused 670 000 deaths globally in 2022. […] Breast cancer occurs in every country of the world. […] In 2022, there were 2.3 million women diagnosed with breast cancer and 670 000 deaths globally. Breast cancer occurs in every country of the world in women at any age after puberty but with increasing rates in later life. […] Female gender is the strongest breast cancer risk factor. […] Approximately 99% of breast cancers occur in women and 0.51% of breast cancers occur in men. […] Certain factors increase the risk of breast cancer including increasing age, obesity, harmful use of alcohol, family history of breast cancer, history of radiation exposure, reproductive history (such as age that menstrual periods began and age at first pregnancy), tobacco use and postmenopausal hormone therapy.

• #48 Breast Cancer Risk Assessment and Screening in Average-Risk Women | ACOG

  https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2017/07/breast-cancer-risk-assessment-and-screening-in-average-risk-women

  The main factors for breast cancer are female sex (more than 99% of cases of breast cancer occur in women) and advancing age. Although other characteristics have been associated with an increased risk of breast cancer, most women in whom invasive breast cancer is diagnosed do not have identifiable risk factors. […] Breast cancer risk appears to differ between postmenopausal women who use combined hormonal therapy and those who use estrogen therapy alone. In the Women’s Health Initiative randomized controlled trial, postmenopausal women taking estrogen and progestin had higher breast cancer risk during the intervention and early postintervention parts of the study. In postmenopausal women who previously had a hysterectomy and were randomized to receive estrogen alone or placebo, breast cancer risk did not appear increased.

• #49

  https://www.who.int/news-room/fact-sheets/detail/breast-cancer

  Breast cancer caused 670 000 deaths globally in 2022. […] Breast cancer occurs in every country of the world. […] In 2022, there were 2.3 million women diagnosed with breast cancer and 670 000 deaths globally. Breast cancer occurs in every country of the world in women at any age after puberty but with increasing rates in later life. […] Female gender is the strongest breast cancer risk factor. […] Approximately 99% of breast cancers occur in women and 0.51% of breast cancers occur in men. […] Certain factors increase the risk of breast cancer including increasing age, obesity, harmful use of alcohol, family history of breast cancer, history of radiation exposure, reproductive history (such as age that menstrual periods began and age at first pregnancy), tobacco use and postmenopausal hormone therapy.

• #50 Epidemiology of breast cancer – Wikipedia

  https://en.wikipedia.org/wiki/Epidemiology_of_breast_cancer

  Worldwide, breast cancer is the most common invasive cancer in women. Breast cancer comprises 22.9% of invasive cancers in women and 16% of all female cancers. […] In 2008, breast cancer caused 458,503 deaths worldwide, which is 13.7% of cancer deaths in women and 6.0% of all cancer deaths for men and women together. […] The number of cases worldwide has significantly increased since the 1970s, a phenomenon partly attributed to the modern lifestyles. […] Breast cancer is strongly related to age, with only 5% of all breast cancers occurring in women under 40 years old. […] The incidence of breast cancer varies greatly around the world: it is lowest in less-developed countries and greatest in the more-developed countries. […] The lifetime risk for breast cancer in the United States is usually given as about 1 in 8 (12%) of women by age 95, with a 1 in 35 (3%) chance of dying from breast cancer.

• #51 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Breast-Cancer-Epidemiology.aspx

  Breast cancer is the most common cancer in women worldwide after skin cancer. It represents 16% of all cancers in women. This rate is twice that of colorectal cancer and cervical cancer and about three times that of lung cancer. Death rates are also 25% greater than that of lung cancer in women. […] All around the world the incidence of this cancer shows varied rates. The rates are low in less-developed countries and greatest in the more-developed countries. Breast cancer is related to age with only 5% of all breast cancers occur in women under 40 years old. […] Breast cancer has been the most common cancer in the UK since 1997. It accounts for 31% of all new cases of cancer in females. In 2010, there were 49,961 new cases of breast cancer in the UK. There are 157 new breast cancer cases for every 100,000 females in the UK.

• #52

  https://www.who.int/news-room/fact-sheets/detail/breast-cancer

  Breast cancer caused 670 000 deaths globally in 2022. […] Breast cancer occurs in every country of the world. […] In 2022, there were 2.3 million women diagnosed with breast cancer and 670 000 deaths globally. Breast cancer occurs in every country of the world in women at any age after puberty but with increasing rates in later life. […] Female gender is the strongest breast cancer risk factor. […] Approximately 99% of breast cancers occur in women and 0.51% of breast cancers occur in men. […] Certain factors increase the risk of breast cancer including increasing age, obesity, harmful use of alcohol, family history of breast cancer, history of radiation exposure, reproductive history (such as age that menstrual periods began and age at first pregnancy), tobacco use and postmenopausal hormone therapy.

• #53 Breast Cancer Epidemiology

  https://www.webmd.com/breast-cancer/breast-cancer-epidemiology

  Epidemiology is the study of how often a health condition affects various groups of people and why. Understanding the epidemiology of breast cancer helps scientists and doctors create new and better ways to prevent and treat it. […] Most breast cancers are diagnosed in women older than 50. Other risks include: A personal or family history of breast cancer, Starting your period before age 12 or starting menopause after 55, Previous radiation therapy to your chest or breasts, Being pregnant for the first time after age 30 or not breastfeeding, Taking birth control pills or hormone therapy, Drinking too much alcohol, Being overweight or obese. […] Breast cancer is most common in middle-aged and older women. Every woman has a 1 in 8 chance of being diagnosed with this cancer at some point in her lifetime.

• #54

  https://www.who.int/news-room/fact-sheets/detail/breast-cancer

  Breast cancer caused 670 000 deaths globally in 2022. […] Breast cancer occurs in every country of the world. […] In 2022, there were 2.3 million women diagnosed with breast cancer and 670 000 deaths globally. Breast cancer occurs in every country of the world in women at any age after puberty but with increasing rates in later life. […] Female gender is the strongest breast cancer risk factor. […] Approximately 99% of breast cancers occur in women and 0.51% of breast cancers occur in men. […] Certain factors increase the risk of breast cancer including increasing age, obesity, harmful use of alcohol, family history of breast cancer, history of radiation exposure, reproductive history (such as age that menstrual periods began and age at first pregnancy), tobacco use and postmenopausal hormone therapy.

• #55

  https://www.who.int/news-room/fact-sheets/detail/breast-cancer

  Family history of breast cancer increases the risk of breast cancer, but most women diagnosed with breast cancer do not have a known family history of the disease. […] Certain inherited high penetrance gene mutations greatly increase breast cancer risk, the most dominant being mutations in the genes BRCA1, BRCA2 and PALB-2. […] The objective of the WHO Global Breast Cancer Initiative (GBCI) is to reduce global breast cancer mortality by 2.5% per year, thereby averting 2.5 million breast cancer deaths globally between 2020 and 2040.

• #56

  https://www.who.int/news-room/fact-sheets/detail/breast-cancer

  Family history of breast cancer increases the risk of breast cancer, but most women diagnosed with breast cancer do not have a known family history of the disease. […] Certain inherited high penetrance gene mutations greatly increase breast cancer risk, the most dominant being mutations in the genes BRCA1, BRCA2 and PALB-2. […] The objective of the WHO Global Breast Cancer Initiative (GBCI) is to reduce global breast cancer mortality by 2.5% per year, thereby averting 2.5 million breast cancer deaths globally between 2020 and 2040.

• #57 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Breast-Cancer-Epidemiology.aspx

  Those with a family history of breast cancer are at double the risk of developing the cancer. About 15% of women who get breast cancer have a family member diagnosed with it. About 5-10% of breast cancers can be linked to gene mutations (abnormal changes) inherited from ones mother or father. […] For women in the U.S., breast cancer death rates are higher than those for any other cancer, besides lung cancer. However, death rates are on the decline due to advances in therapeutics against breast cancer. […] Breast cancer is the most common cancer among Australian women after melanoma or skin cancers. Breast cancers accounted for 28.2 per cent of all new cancers in women in 2008. Breast cancer is the second leading cause of cancer-related death in Australian women, accounting for 15.5 per cent of all cancer deaths in women in 2007.

• #58 Breast Cancer Risk Assessment and Screening in Average-Risk Women | ACOG

  https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2017/07/breast-cancer-risk-assessment-and-screening-in-average-risk-women

  The main factors for breast cancer are female sex (more than 99% of cases of breast cancer occur in women) and advancing age. Although other characteristics have been associated with an increased risk of breast cancer, most women in whom invasive breast cancer is diagnosed do not have identifiable risk factors. […] Breast cancer risk appears to differ between postmenopausal women who use combined hormonal therapy and those who use estrogen therapy alone. In the Women’s Health Initiative randomized controlled trial, postmenopausal women taking estrogen and progestin had higher breast cancer risk during the intervention and early postintervention parts of the study. In postmenopausal women who previously had a hysterectomy and were randomized to receive estrogen alone or placebo, breast cancer risk did not appear increased.

• #59 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Breast-Cancer-Epidemiology.aspx

  Higher incidence rates are seen among older women, supporting a link with hormonal status. Between 2008 and 2010, an average of 45% of cases were diagnosed in women aged 65 years and over, and 80% were diagnosed in the 50s and over. Nearly half (48%) of female breast cancer cases are diagnosed in the 50-69 age group. Incidence is lower among women from low socioeconomic strata. […] The lifetime risk of developing breast cancer in the UK is estimated to be 1 in 8 for women. Among all detected cases 41% in 2009 were detected as stage 1, 45% at stage II, 9% at stage III and 5% at stage IV. […] In the US, around 1 in 8 women carry a lifetime risk of invasive breast cancer. In 2011, an estimated 230,480 new cases of invasive breast cancer were expected to be diagnosed in women in the U.S., along with 57,650 new cases of non-invasive (in situ) breast cancer.

• #60 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Breast-Cancer-Epidemiology.aspx

  Higher incidence rates are seen among older women, supporting a link with hormonal status. Between 2008 and 2010, an average of 45% of cases were diagnosed in women aged 65 years and over, and 80% were diagnosed in the 50s and over. Nearly half (48%) of female breast cancer cases are diagnosed in the 50-69 age group. Incidence is lower among women from low socioeconomic strata. […] The lifetime risk of developing breast cancer in the UK is estimated to be 1 in 8 for women. Among all detected cases 41% in 2009 were detected as stage 1, 45% at stage II, 9% at stage III and 5% at stage IV. […] In the US, around 1 in 8 women carry a lifetime risk of invasive breast cancer. In 2011, an estimated 230,480 new cases of invasive breast cancer were expected to be diagnosed in women in the U.S., along with 57,650 new cases of non-invasive (in situ) breast cancer.

• #61 Gestational breast cancer: Epidemiology and diagnosis – UpToDate

  https://www.uptodate.com/contents/gestational-breast-cancer-epidemiology-and-diagnosis

  In women under age 30, as many as 20 percent of breast cancers are pregnancy associated; however, in women under age 50, fewer than 5 percent are pregnancy associated, given that the risk of nonpregnancy-associated breast cancer increases with age. […] Pregnancy-associated (or gestational) breast cancer is a relatively uncommon event. The incidence of pregnancy-associated breast cancer (for the prenatal to postpartum period) is approximately 15 to 35 per 100,000 deliveries, with fewer breast cancer cases diagnosed during pregnancy than during the first postpartum year. The incidence of pregnancy-associated breast cancer appears to be increasing as more women delay childbearing.

• #62 Gestational breast cancer: Epidemiology and diagnosis – UpToDate

  https://www.uptodate.com/contents/gestational-breast-cancer-epidemiology-and-diagnosis

  In women under age 30, as many as 20 percent of breast cancers are pregnancy associated; however, in women under age 50, fewer than 5 percent are pregnancy associated, given that the risk of nonpregnancy-associated breast cancer increases with age. […] Pregnancy-associated (or gestational) breast cancer is a relatively uncommon event. The incidence of pregnancy-associated breast cancer (for the prenatal to postpartum period) is approximately 15 to 35 per 100,000 deliveries, with fewer breast cancer cases diagnosed during pregnancy than during the first postpartum year. The incidence of pregnancy-associated breast cancer appears to be increasing as more women delay childbearing.

• #63 Approach to the patient following treatment for breast cancer – UpToDate

  https://www.uptodate.com/contents/approach-to-the-patient-following-treatment-for-breast-cancer

  According to statistics from the International Agency for Research on Cancer (IARC), there are approximately 44 million people living with cancer worldwide. In the United States, the five-year survival rate for female breast cancer is approximately 90 percent, with data indicating decreasing recurrences over time. Additionally, although the vast majority of breast cancer survivors are women, approximately 2500 men are diagnosed with breast cancer annually in the United States alone, and most will achieve long-term disease-free survival. […] Patients who are living for decades beyond cancer experience the normal issues of aging, which are often compounded by the long-term effects of having had cancer and cancer therapy. These patients are at risk for a breast cancer recurrence (which is most common in the first five years but may occur even decades following treatment), a new primary breast cancer, other cancers, and short-term and long-term adverse effects of treatment. Additional issues for cancer survivors relate to psychologic, genetic, reproductive, social, and employment concerns.

• #64 Breast Cancer Facts & Stats 2024 – Incidence, Age, Survival, & More

  https://www.nationalbreastcancer.org/breast-cancer-facts/

  In 2025, an estimated 316,950 new cases of invasive breast cancer will be diagnosed in women in the U.S., as well as 59,080 new cases of non-invasive (in situ) breast cancer. […] There are currently over 4 million breast cancer survivors in the United States. […] The 5-year relative survival rate for cancer diagnosed at the localized stage is 99%. […] Breast cancer is the most common cancer in American women, except for skin cancers. […] Approximately 66% of breast cancer cases are diagnosed at a localized stage, before cancer has spread outside of the breast, when it is easiest to treat. […] Breast cancer death rates have slowly decreased since 1989, for an overall decline of 43% through 2020. This is in part due to better screening and early detection efforts, increased awareness, and continually improving treatment options. […] Women who receive regular screenings for breast cancer have a 26% lower breast cancer death rate than women who do not receive screenings. […] In 2025, an estimated 2,800 men will be diagnosed with invasive breast cancer in the United States.

• #65 Breast cancer: Epidemiology, risk factors and screening

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10774137/

  Breast cancer is a global health concern with a significant impact on the well-being of women. Worldwide, the past several decades have witnessed changes in the incidence and mortality of breast cancer. Additionally, epidemiological data reveal distinct geographic and demographic disparities globally. […] Screening plays a critical role in the effective management of breast cancer. Various screening modalities, including mammography, ultrasound, magnetic resonance imaging (MRI), and physical examination, have different applications, and a combination of these modalities is applied in practice. Current screening recommendations are based on factors including age and risk, with a significant emphasis on minimizing potential harms to achieve an optimal benefits-to-harms ratio. This review provides a comprehensive insight into the epidemiology, risk factors, and screening of breast cancer. Understanding these elements is crucial for improving breast cancer management and reducing its burden on affected individuals and healthcare systems.

• #66 Breast cancer: Epidemiology, risk factors and screening

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10774137/

  Globally, there exist notable variations across different regions and among various ethnicity, often reflecting a complex interplay of genetic, environmental, socioeconomic, and healthcare access factors. It has been observed that countries with a high human development index (HDI) like Northern America, Australia, and Northern and Western Europe, tend to have a higher incidence of breast cancer compared to those with a lower HDI. […] The stage at diagnosis of breast cancer tends to be later in countries like those in sub-Saharan Africa, as indicated by a meta-analysis. […] Breast cancer screening, which involves various methods, is part of a secondary prevention strategy for breast cancer, facilitating early detection and treatment. Though the screening is recommended by different guidelines of breast cancer, it is important to balance the benefits and harms of screening and to select suitable screening modality for each patient.

• #67 Recommendation: Breast Cancer: Screening | United States Preventive Services Taskforce

  https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-screening

  The Task Force now recommends that all women get screened every other year starting at age 40. This final recommendation also urgently calls for research in key areas. […] The Task Force recommends that all women get screened for breast cancer every other year, starting at age 40 and continuing through age 74, to reduce their risk of dying from this disease. This is a B grade. […] We are urgently calling for more research that will allow us to build on our existing guidance and help all women live longer and healthier lives. […] Black women are 40 percent more likely to die from breast cancer than White women and too often get aggressive cancers at young ages. Ensuring Black women start screening at 40 is an important first step, yet it is not enough to improve these inequities. […] The USPSTF concludes with moderate certainty that biennial screening mammography in women aged 40 to 74 years has a moderate net benefit.

• #68 Recommendation: Breast Cancer: Screening | United States Preventive Services Taskforce

  https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-screening

  The Task Force now recommends that all women get screened every other year starting at age 40. This final recommendation also urgently calls for research in key areas. […] The Task Force recommends that all women get screened for breast cancer every other year, starting at age 40 and continuing through age 74, to reduce their risk of dying from this disease. This is a B grade. […] We are urgently calling for more research that will allow us to build on our existing guidance and help all women live longer and healthier lives. […] Black women are 40 percent more likely to die from breast cancer than White women and too often get aggressive cancers at young ages. Ensuring Black women start screening at 40 is an important first step, yet it is not enough to improve these inequities. […] The USPSTF concludes with moderate certainty that biennial screening mammography in women aged 40 to 74 years has a moderate net benefit.

• #69 Recommendation: Breast Cancer: Screening | United States Preventive Services Taskforce

  https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-screening

  The USPSTF concludes that the evidence is insufficient to determine the balance of benefits and harms of screening mammography in women 75 years or older. […] The USPSTF concludes that the evidence is insufficient to determine the balance of benefits and harms of supplemental screening for breast cancer with breast ultrasound or MRI, regardless of breast density. […] Mortality from breast cancer is highest for Black women, even when accounting for differences in age and stage at diagnosis; mortality is approximately 40% higher for Black women compared with White women. […] Black women have a higher incidence of breast cancer with at least 1 negative molecular marker, and the incidence of triple-negative cancers is twice as high in Black women compared with White women. […] Improvements in access to effective health care, removal of financial barriers, and use of support services to ensure equitable follow-up after screening and timely and effective treatment of breast cancer have the potential to reduce mortality for individuals experiencing disparities related to racism, rural location, low income, or other factors associated with lower breast cancer survival.

• #70 Krebs – Breast cancer

  https://www.krebsdaten.de/Krebs/EN/Content/Cancer_sites/Breast_cancer/breast_cancer_node.html

  Some breast cancers are due to an increased genetic risk: Women whose close relatives have been diagnosed with breast or ovarian cancer have an elevated risk of developing breast cancer themselves. […] Lifestyle factors such as overweight and lack of exercise after menopause as well as alcohol consumption are also risk factors. […] The early detection programme of the statutory health insurance offers women 30 years of age and over an annual palpation examination by a physician.

• #71 Primary Care of Breast Cancer Survivors | AAFP

  https://www.aafp.org/pubs/afp/issues/2019/0315/p370.html

  Because of the declining mortality rates, most patients with breast cancer survive and require ongoing surveillance for recurrence and management of sequelae from the disease or its treatment. Primary care physicians are often involved in the care of these patients. […] Guidelines published by the American Cancer Society/American Society of Clinical Oncology emphasize that primary care physicians should ensure that breast cancer survivors follow the recommendations of the oncology team, as well as receive a history and physical examination every three to six months for the first three years after treatment, every six to 12 months for two more years, then annually thereafter. Patients should also be educated about the signs and symptoms of local recurrence. […] Radiologic surveillance should consist of annual mammography of both breasts or the remaining breast. Annual magnetic resonance imaging should be performed only in patients at high risk of recurrence. Risk factors for recurrence include a calculated lifetime risk of more than 20%, a strong family history of breast or ovarian cancer, and a personal history of Hodgkin disease.

• #72 Primary Care of Breast Cancer Survivors | AAFP

  https://www.aafp.org/pubs/afp/issues/2019/0315/p370.html

  Because of the declining mortality rates, most patients with breast cancer survive and require ongoing surveillance for recurrence and management of sequelae from the disease or its treatment. Primary care physicians are often involved in the care of these patients. […] Guidelines published by the American Cancer Society/American Society of Clinical Oncology emphasize that primary care physicians should ensure that breast cancer survivors follow the recommendations of the oncology team, as well as receive a history and physical examination every three to six months for the first three years after treatment, every six to 12 months for two more years, then annually thereafter. Patients should also be educated about the signs and symptoms of local recurrence. […] Radiologic surveillance should consist of annual mammography of both breasts or the remaining breast. Annual magnetic resonance imaging should be performed only in patients at high risk of recurrence. Risk factors for recurrence include a calculated lifetime risk of more than 20%, a strong family history of breast or ovarian cancer, and a personal history of Hodgkin disease.

• #73 Surveillance and imaging | Cancer Australia

  https://www.canceraustralia.gov.au/cancer-types/breast-cancer/guidance-early-management-breast-cancer/follow-and-survivorship-1

  Follow-up imaging […] Patients who have undergone breast-conserving surgery should be referred for annual mammography of both breasts. Patients who have undergone a unilateral mastectomy should be referred for annual mammography on the intact breast. Patients may choose to return to BreastScreen for routine annual mammographic surveillance after 5 years. Consider the addition of ultrasound to mammography for follow-up, when indicated on clinical or radiological grounds. […] In patients less than 50 years of age who are carriers of high-risk gene mutations (e.g. BRCA1/2) and who have not undergone risk-reducing mastectomy, consider the use of annual magnetic resonance imaging (MRI) of both breasts during follow-up. […] In patients who have undergone breast-conserving surgery or a mastectomy and breast reconstruction, diagnostic imaging (mammography, ultrasound, or magnetic resonance imaging) is useful in the evaluation of new symptoms (e.g. lumps, skin changes).

• #74 Surveillance and imaging | Cancer Australia

  https://www.canceraustralia.gov.au/cancer-types/breast-cancer/guidance-early-management-breast-cancer/follow-and-survivorship-1

  Follow-up imaging […] Patients who have undergone breast-conserving surgery should be referred for annual mammography of both breasts. Patients who have undergone a unilateral mastectomy should be referred for annual mammography on the intact breast. Patients may choose to return to BreastScreen for routine annual mammographic surveillance after 5 years. Consider the addition of ultrasound to mammography for follow-up, when indicated on clinical or radiological grounds. […] In patients less than 50 years of age who are carriers of high-risk gene mutations (e.g. BRCA1/2) and who have not undergone risk-reducing mastectomy, consider the use of annual magnetic resonance imaging (MRI) of both breasts during follow-up. […] In patients who have undergone breast-conserving surgery or a mastectomy and breast reconstruction, diagnostic imaging (mammography, ultrasound, or magnetic resonance imaging) is useful in the evaluation of new symptoms (e.g. lumps, skin changes).

• #75 Surveillance | Center for BRCA Research

  https://brca.ucsf.edu/surveillance

  Surveillance involves regular screenings and other tests depending on the specific cancer risk. Early detection through surveillance does not prevent cancer but can increase the chances of early intervention and successful treatment. […] Breast cancer surveillance for people born female starts at around age 25. This included self breast exams, a clinical breast exam every 6 months, and a breast MRI once a year. Women should also have additional mammogram screenings when older. […] MRIs can detect small tumors or abnormalities that may not be visible on mammograms or felt in a clinical breast exam, making MRIs more reliable for catching breast cancer at early stages.

• #76 Surveillance | Center for BRCA Research

  https://brca.ucsf.edu/surveillance

  Surveillance involves regular screenings and other tests depending on the specific cancer risk. Early detection through surveillance does not prevent cancer but can increase the chances of early intervention and successful treatment. […] Breast cancer surveillance for people born female starts at around age 25. This included self breast exams, a clinical breast exam every 6 months, and a breast MRI once a year. Women should also have additional mammogram screenings when older. […] MRIs can detect small tumors or abnormalities that may not be visible on mammograms or felt in a clinical breast exam, making MRIs more reliable for catching breast cancer at early stages.

• #77 Surveillance | Center for BRCA Research

  https://brca.ucsf.edu/surveillance

  Surveillance involves regular screenings and other tests depending on the specific cancer risk. Early detection through surveillance does not prevent cancer but can increase the chances of early intervention and successful treatment. […] Breast cancer surveillance for people born female starts at around age 25. This included self breast exams, a clinical breast exam every 6 months, and a breast MRI once a year. Women should also have additional mammogram screenings when older. […] MRIs can detect small tumors or abnormalities that may not be visible on mammograms or felt in a clinical breast exam, making MRIs more reliable for catching breast cancer at early stages.

• #78 Breast Cancer Surveillance Consortium (BCSC)

  https://www.bcsc-research.org/

  A collaborative network of breast imaging registries conducting research to assess and improve the delivery and quality of breast cancer screening and related patient outcomes in the United States. […] New BCSC study clarifies the association between breast density and cancer risk. […] New BCSC study reveals racial and ethnic differences in the receipt of some diagnostic imaging and biopsy services by women with abnormal screening mammogram results. […] New BCSC study reveals using digital breast tomosynthesis (DBT) and supplemental MRI yields more benefits but also confers more risks, according to simulation data.

• #79 About the BCSC :: BCSC

  https://www.bcsc-research.org/index.php/about

  The Breast Cancer Surveillance Consortium (BCSC) is a collaborative network of six active breast imaging registries and two historic registries focused on research to assess and improve the delivery and quality of breast cancer screening and related outcomes in the United States. […] Two important objectives of the BCSC are to enhance the current understanding of breast cancer screening practices and to help improve the practice of community-based mammography screening for women with and without a personal history of breast cancer. […] The Breast Cancer Surveillance Consortium (BCSC) conducts rigorous research to improve breast cancer screening and detection and reduce the burden of breast cancer. […] The BCSC collects research data on breast cancer screening, diagnosis, and outcomes.

• #80 Surveillance, Epidemiology, and End Results Program

  https://seer.cancer.gov/

  SEER is an authoritative source for cancer statistics in the United States. […] The Surveillance, Epidemiology, and End Results (SEER) Program provides information on cancer statistics in an effort to reduce the cancer burden among the U.S. population. […] Released April 16, 2025 SEER Incidence Data, 1975-2022 SEER*Explorer with Statistics through 2022 […] December 10, 2024 Tweet Rates of distant-stage breast cancer on the rise External Web Site Policy.

• #81 What CDC Is Doing About Breast Cancer | Breast Cancer | CDC

  https://www.cdc.gov/breast-cancer/what-cdc-is-doing/index.html

  CDC is working to prevent and control breast cancer in several ways. […] The ASTHO Breast Cancer Disparities Online Toolkit provides resources for identifying, measuring, and addressing disparities in avoidable deaths from breast cancer among different groups of women. […] Cancer surveillance is the collection of information about cancer, including: Which groups of people were diagnosed with breast cancer. […] This information allows scientists to: See how breast cancer rates change over time and whether more women are being diagnosed before their cancer has spread. […] CDC supports cancer surveillance through: National Program of Cancer Registries: Funded by CDC, this program collects information about cancers diagnosed in the United States through central cancer registries. […] The BRFSS also collects information about breast cancer screening.

• #82 Vermont Breast Cancer Surveillance System | The University of Vermont

  https://www.uvm.edu/larnermed/vbcss

  The Vermont Breast Cancer Surveillance System (VBCSS) partners with healthcare facilities and the Vermont Department of Health to collect statewide breast imaging, pathology, and cancer registry data, in support of quality improvement and research in breast cancer screening and diagnosis. […] Radiology facilities in Vermont work with the Vermont Mammography Registry to collect information to better understand the cause, prevention, early detection, and treatment of breast cancer.

• #83 MSK RISE: High Risk Breast Cancer Screening Program

  https://www.mskcc.org/cancer-conditions/breast-cancer/msk-rise-high-risk-breast-cancer-screening-program

  MSK RISE is a breast cancer screening program. Its for people considered at a high risk for getting breast cancer. […] High risk people are cared for differently. If youre considered high risk for breast cancer, well watch you for early signs of cancer. […] RISE (Risk Assessment, Imaging, Surveillance, and Education) is a breast cancer screening program. Our experts will assess whether youre at higher risk for breast cancer. If you are, well make a long-term surveillance plan just for you. […] Surveillance means monitoring or watching. This program monitors you for early signs of breast cancer. […] We will watch you by screening for breast cancer on a schedule thats right for your level of risk. […] MSK can find the best options for you. […] If you have a higher risk for breast cancer, well make a personal plan for you through RISE.

• #84 Breast cancer: Epidemiology, risk factors and screening

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10774137/

  Currently, breast cancer screening programs are well-established in developed regions like Europe and the US. For example, nearly all European countries have population-based screening programs, though inequalities between them have been identified. In contrast, in low-income areas such as sub-Saharan Africa, no countries have established systematic screening programs, and awareness of breast cancer is poor.

• #85 Breast Cancer Statistics | Breast Cancer | CDC

  https://www.cdc.gov/breast-cancer/statistics/index.html

  Breast cancer is the second most common cancer among women in the United States. Breast cancer is the second leading cause of cancer death among women in the United States. For non-Hispanic Black women and Hispanic women, breast cancer is the leading cause of cancer death. […] The Breast Cancer Stat Bite provides an overview of incidence, deaths, stage distribution, and 5-year relative survival. […] Cancer Statistics At a Glance: See rates or numbers of new breast cancers or breast cancer deaths for the entire United States and individual states. […] Cancers by Age, Sex, Race, and Ethnicity: See rates or numbers of new breast cancers or breast cancer deaths by race and ethnicity and age group. […] Trends: See how the rates of new breast cancers or breast cancer deaths changed over time for the entire United States and individual states.

• #86 Breast Cancer Statistics | Breast Cancer | CDC

  https://www.cdc.gov/breast-cancer/statistics/index.html

  Breast cancer is the second most common cancer among women in the United States. Breast cancer is the second leading cause of cancer death among women in the United States. For non-Hispanic Black women and Hispanic women, breast cancer is the leading cause of cancer death. […] The Breast Cancer Stat Bite provides an overview of incidence, deaths, stage distribution, and 5-year relative survival. […] Cancer Statistics At a Glance: See rates or numbers of new breast cancers or breast cancer deaths for the entire United States and individual states. […] Cancers by Age, Sex, Race, and Ethnicity: See rates or numbers of new breast cancers or breast cancer deaths by race and ethnicity and age group. […] Trends: See how the rates of new breast cancers or breast cancer deaths changed over time for the entire United States and individual states.

• #87 Recommendation: Breast Cancer: Screening | United States Preventive Services Taskforce

  https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-screening

  The USPSTF concludes that the evidence is insufficient to determine the balance of benefits and harms of screening mammography in women 75 years or older. […] The USPSTF concludes that the evidence is insufficient to determine the balance of benefits and harms of supplemental screening for breast cancer with breast ultrasound or MRI, regardless of breast density. […] Mortality from breast cancer is highest for Black women, even when accounting for differences in age and stage at diagnosis; mortality is approximately 40% higher for Black women compared with White women. […] Black women have a higher incidence of breast cancer with at least 1 negative molecular marker, and the incidence of triple-negative cancers is twice as high in Black women compared with White women. […] Improvements in access to effective health care, removal of financial barriers, and use of support services to ensure equitable follow-up after screening and timely and effective treatment of breast cancer have the potential to reduce mortality for individuals experiencing disparities related to racism, rural location, low income, or other factors associated with lower breast cancer survival.

• #88 Recommendation: Breast Cancer: Screening | United States Preventive Services Taskforce

  https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-screening

  The USPSTF concludes that the evidence is insufficient to determine the balance of benefits and harms of screening mammography in women 75 years or older. […] The USPSTF concludes that the evidence is insufficient to determine the balance of benefits and harms of supplemental screening for breast cancer with breast ultrasound or MRI, regardless of breast density. […] Mortality from breast cancer is highest for Black women, even when accounting for differences in age and stage at diagnosis; mortality is approximately 40% higher for Black women compared with White women. […] Black women have a higher incidence of breast cancer with at least 1 negative molecular marker, and the incidence of triple-negative cancers is twice as high in Black women compared with White women. […] Improvements in access to effective health care, removal of financial barriers, and use of support services to ensure equitable follow-up after screening and timely and effective treatment of breast cancer have the potential to reduce mortality for individuals experiencing disparities related to racism, rural location, low income, or other factors associated with lower breast cancer survival.

• #89 Breast Cancer Epidemiology

  https://www.webmd.com/breast-cancer/breast-cancer-epidemiology

  Black women often get breast cancer at a younger age than white women. They’re also more likely to have fast-growing breast cancers like triple-negative breast cancer. And they’re 41 percent more likely to die from breast cancer than white women. […] Early detection and new treatments mean more people survive breast cancer than in the past. The relative survival rate for all breast cancers is more than 90 percent. Relative survival means that people with breast cancer are 90 percent as likely to live for 5 years as people without this cancer. […] Breast cancer treatment varies based on your cancer type, tumor size, and other factors, such as whether hormones play a role in its growth. Older treatments like surgery, radiation, and chemotherapy aim to kill as many cancer cells as possible. Most people still get one or more of these treatments.

• #90 Triple Negative Breast Cancer Epidemiology | Oncology Nurses Quality Improvement Series

  https://oncologynurse-ce.com/triple-negative-breast-cancer-epidemiology/

  Incidence and characteristics of TNBC can also vary by ethnicity: In the Carolina Breast Cancer Study (compared with white women (n=631), African American women (n = 518) were less likely to have HR+/HER2- disease (48 versus 64 percent, respectively) and more likely to have triple negative disease (22 versus 11 percent, respectively). […] The highest rates of new TNBC cases have been demonstrated in black females. […] Those diagnosed with subtypes of either TNBC or any HER2+ disease may be more likely to diagnosed at a younger age, belong to a minority group and be diagnosed at a later stage.

• #91 Triple Negative Breast Cancer Epidemiology | Oncology Nurses Quality Improvement Series

  https://oncologynurse-ce.com/triple-negative-breast-cancer-epidemiology/

  Incidence and characteristics of TNBC can also vary by ethnicity: In the Carolina Breast Cancer Study (compared with white women (n=631), African American women (n = 518) were less likely to have HR+/HER2- disease (48 versus 64 percent, respectively) and more likely to have triple negative disease (22 versus 11 percent, respectively). […] The highest rates of new TNBC cases have been demonstrated in black females. […] Those diagnosed with subtypes of either TNBC or any HER2+ disease may be more likely to diagnosed at a younger age, belong to a minority group and be diagnosed at a later stage.

• #92 Florida Study: Decline in Breast Cancer Death Disparity | AACR

  https://www.aacr.org/patients-caregivers/progress-against-cancer/florida-study-shows-breast-cancer-death-rates-decreasing-faster-for-black-women-than-white-women/

  Florida study found that the breast cancer death rate for Black women remained higher than for White women. […] The disparity gap in breast cancer survival rates between Black and white women in Florida is closing, but more work remains to be done, according to results of a study published in Cancer Epidemiology, Biomarkers Prevention. […] In the most recent time period, non-Hispanic Black women have twice the rate of breast cancer death compared to non-Hispanic white women. […] They found that breast cancer mortality has decreased over time for all racial and ethnic groups, and minorities had greater absolute and relative improvement for nearly all metrics compared to non-Hispanic white women. […] For the most recent time period in the study, Black women still experienced significant survival disparities, with non-Hispanic Black women having twice the rate of death from breast cancer five years and 10 years after diagnosis.

• #93 Florida Study: Decline in Breast Cancer Death Disparity | AACR

  https://www.aacr.org/patients-caregivers/progress-against-cancer/florida-study-shows-breast-cancer-death-rates-decreasing-faster-for-black-women-than-white-women/

  Adjustment for other factors substantially reduced the excess rate of breast cancer death for Black women. […] When the researchers adjusted the mortality data for age, insurance status, census-tract poverty, tumor stage and grade at diagnosis, and treatment received, the 10-year relative rate of breast cancer mortality for Black women decreased to 20 percent higher than white women. […] These factors, as a group, explained a lot of the disparity.

• #94 Recommendation: Breast Cancer: Screening | United States Preventive Services Taskforce

  https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-screening

  The USPSTF concludes that the evidence is insufficient to determine the balance of benefits and harms of screening mammography in women 75 years or older. […] The USPSTF concludes that the evidence is insufficient to determine the balance of benefits and harms of supplemental screening for breast cancer with breast ultrasound or MRI, regardless of breast density. […] Mortality from breast cancer is highest for Black women, even when accounting for differences in age and stage at diagnosis; mortality is approximately 40% higher for Black women compared with White women. […] Black women have a higher incidence of breast cancer with at least 1 negative molecular marker, and the incidence of triple-negative cancers is twice as high in Black women compared with White women. […] Improvements in access to effective health care, removal of financial barriers, and use of support services to ensure equitable follow-up after screening and timely and effective treatment of breast cancer have the potential to reduce mortality for individuals experiencing disparities related to racism, rural location, low income, or other factors associated with lower breast cancer survival.

• #95 Breast Cancer Facts & Stats 2024 – Incidence, Age, Survival, & More

  https://www.nationalbreastcancer.org/breast-cancer-facts/

  In 2025, an estimated 316,950 new cases of invasive breast cancer will be diagnosed in women in the U.S., as well as 59,080 new cases of non-invasive (in situ) breast cancer. […] There are currently over 4 million breast cancer survivors in the United States. […] The 5-year relative survival rate for cancer diagnosed at the localized stage is 99%. […] Breast cancer is the most common cancer in American women, except for skin cancers. […] Approximately 66% of breast cancer cases are diagnosed at a localized stage, before cancer has spread outside of the breast, when it is easiest to treat. […] Breast cancer death rates have slowly decreased since 1989, for an overall decline of 43% through 2020. This is in part due to better screening and early detection efforts, increased awareness, and continually improving treatment options. […] Women who receive regular screenings for breast cancer have a 26% lower breast cancer death rate than women who do not receive screenings. […] In 2025, an estimated 2,800 men will be diagnosed with invasive breast cancer in the United States.

• #96 Breast Cancer Facts & Stats 2024 – Incidence, Age, Survival, & More

  https://www.nationalbreastcancer.org/breast-cancer-facts/

  In 2025, an estimated 316,950 new cases of invasive breast cancer will be diagnosed in women in the U.S., as well as 59,080 new cases of non-invasive (in situ) breast cancer. […] There are currently over 4 million breast cancer survivors in the United States. […] The 5-year relative survival rate for cancer diagnosed at the localized stage is 99%. […] Breast cancer is the most common cancer in American women, except for skin cancers. […] Approximately 66% of breast cancer cases are diagnosed at a localized stage, before cancer has spread outside of the breast, when it is easiest to treat. […] Breast cancer death rates have slowly decreased since 1989, for an overall decline of 43% through 2020. This is in part due to better screening and early detection efforts, increased awareness, and continually improving treatment options. […] Women who receive regular screenings for breast cancer have a 26% lower breast cancer death rate than women who do not receive screenings. […] In 2025, an estimated 2,800 men will be diagnosed with invasive breast cancer in the United States.

• #97 Breast Cancer Epidemiology – Maina Foundation

  https://mainafoundation.org/breast-cancer-fast-facts/

  Most frequent cancer among women impacts 2.1 million women each year. […] Cause of the most cancer-related deaths among women. […] In 2018, approximately 627,000 women died from breast cancer (15% of all cancer deaths among women). […] Breast cancer rates are higher among women in more developed regions, however rates are increasing in nearly every region worldwide. […] Breast cancer is the second leading cause of cancer death in women. […] About 1 in 8 U.S. women (about 12%) will develop invasive breast cancer in her lifetime. […] In recent years, incidence rates have increased slightly (by 0.3% per year). […] About 85% of breast cancers occur in women who have no family history of breast cancer. […] The female breast cancer death rate peaked at 33.2 per 100,000 in 1989 and decreased by 40% to 19.8 in 2017.

• #98 Breast cancer in the world: Incidence and mortality

  https://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0036-36342011000500005

  The geographical pattern described in Cancer Incidence in Five Continents, Volume IX allows us to identify the highest and lowest rates of cancer incidence worldwide based on PBCRs data. […] The highest incidence rates of breast cancer in Africa are estimated for South African Republic and the lowest rates for Sudan and Ghana. […] In Asia, an increasing trend was observed for the ASR in Japan and Korea, whereas the ASR in Hong Kong appeared to be slowly decreasing. […] Breast cancer mortality is decreasing in USA among all races for the period 1972-2007 from 31 to 23 per 100 000 deaths in the last five years (the age-adjusted death rate was 24.0 per 100 000 women per year). […] Breast cancer is the most common cancer in the world in women in this decade; however its incidence is decreasing in North America. In most of the countries in the world there is still a public health issue. […] A lot has been done to reduce the burden of breast cancer in the world as new treatment modalities, organizing screening programs which have improved the survival of the women diagnosed with breast cancer.

• #99 Breast Cancer Epidemiology – Maina Foundation

  https://mainafoundation.org/breast-cancer-fast-facts/

  Most frequent cancer among women impacts 2.1 million women each year. […] Cause of the most cancer-related deaths among women. […] In 2018, approximately 627,000 women died from breast cancer (15% of all cancer deaths among women). […] Breast cancer rates are higher among women in more developed regions, however rates are increasing in nearly every region worldwide. […] Breast cancer is the second leading cause of cancer death in women. […] About 1 in 8 U.S. women (about 12%) will develop invasive breast cancer in her lifetime. […] In recent years, incidence rates have increased slightly (by 0.3% per year). […] About 85% of breast cancers occur in women who have no family history of breast cancer. […] The female breast cancer death rate peaked at 33.2 per 100,000 in 1989 and decreased by 40% to 19.8 in 2017.

• #100 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Breast-Cancer-Epidemiology.aspx

  Those with a family history of breast cancer are at double the risk of developing the cancer. About 15% of women who get breast cancer have a family member diagnosed with it. About 5-10% of breast cancers can be linked to gene mutations (abnormal changes) inherited from ones mother or father. […] For women in the U.S., breast cancer death rates are higher than those for any other cancer, besides lung cancer. However, death rates are on the decline due to advances in therapeutics against breast cancer. […] Breast cancer is the most common cancer among Australian women after melanoma or skin cancers. Breast cancers accounted for 28.2 per cent of all new cancers in women in 2008. Breast cancer is the second leading cause of cancer-related death in Australian women, accounting for 15.5 per cent of all cancer deaths in women in 2007.

• #101 Krebs – Breast cancer

  https://www.krebsdaten.de/Krebs/EN/Content/Cancer_sites/Breast_cancer/breast_cancer_node.html

  With approximately 74,500 annual incident cases, breast cancer is by far the most common cancer in women. […] Based on current incidence rates, about one in eight women is expected to develop breast cancer over the course of a lifetime. Almost one out of six affected women are below 55 years of age at diagnosis. […] Following the introduction of mammography screening between 2005 and 2009, the rates of new cases show a typical trend with a significant increase at the beginning of the program and a subsequent slow decline. […] Progress in therapy has substantially improved the survival chances of people diagnosed with breast cancer, and this has led to a decrease in mortality rates as well. […] Hormones can influence the risk of disease: Early first and late last menstruation, childlessness or a higher age at first birth are considered risk factors.

• #102 Female Breast Cancer — Cancer Stat Facts

  https://seer.cancer.gov/statfacts/html/breast.html

  The rate of new cases of female breast cancer was 130.8 per 100,000 women per year based on 2018-2022 cases, age-adjusted. […] Overall, female breast cancer survival is good. However, women who are diagnosed at an advanced age may be more likely than younger women to die of the disease. Female breast cancer is the fourth leading cause of cancer death in the United States. The death rate was 19.2 per 100,000 women per year based on 2019-2023, age-adjusted. […] The percent of female breast cancer deaths is highest among women aged 65-74. […] Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments. […] Using statistical models for analysis, age-adjusted rates for new female breast cancer cases have been rising on average 0.6% each year over 2013-2022. Age-adjusted death rates have been falling on average 1.2% each year over 2014-2023.

• #103 The Epidemiology of Breast Cancer – Breast Cancer – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK583819/

  In the developing world, women have a 17% higher BC mortality rate due to a lack of defined early screening standards and poor or delayed access to treatment. […] The highest 5-year survival rate (99.1%) in the USA is seen in BC cases with tumors localized to the initial place of origin. […] The 5-year survival rate from 2012 to 2018 was 90.6%. […] According to the American Cancer Society, 43,250 women and 530 men are expected to die from BC in 2022, while the projected 2040 BC mortality is expected to decrease to 30,000 deaths. […] Overall, the incidence of breast cancer has doubled in the last few decades in 60/102 countries, including Argentina, Brazil, and Afghanistan. […] Better organized screening programs, establishment of breast cancer registries, and more widespread use of mammography screening in lower developmental regions of the world can increase early-stage breast cancer diagnosis, reduce breast cancer-related mortality, and help reduce future global breast cancer burden.

• #104 The Epidemiology of Breast Cancer – Breast Cancer – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK583819/

  In the developing world, women have a 17% higher BC mortality rate due to a lack of defined early screening standards and poor or delayed access to treatment. […] The highest 5-year survival rate (99.1%) in the USA is seen in BC cases with tumors localized to the initial place of origin. […] The 5-year survival rate from 2012 to 2018 was 90.6%. […] According to the American Cancer Society, 43,250 women and 530 men are expected to die from BC in 2022, while the projected 2040 BC mortality is expected to decrease to 30,000 deaths. […] Overall, the incidence of breast cancer has doubled in the last few decades in 60/102 countries, including Argentina, Brazil, and Afghanistan. […] Better organized screening programs, establishment of breast cancer registries, and more widespread use of mammography screening in lower developmental regions of the world can increase early-stage breast cancer diagnosis, reduce breast cancer-related mortality, and help reduce future global breast cancer burden.

• #105 Breast Cancer Statistics And Resources | Breast Cancer Research Foundation

  https://www.bcrf.org/breast-cancer-statistics-and-resources/

  Breast cancer is the most common cancer among American women after nonmelanoma skin cancer. […] In 2025, an estimated 319,750 people will be diagnosed with breast cancer in the U.S. […] In 2025, an estimated 316,950 women will be diagnosed with breast cancer in the U.S., making it the most common cancer in American women. Every two minutes a woman in the U.S. is diagnosed with the disease. […] In 2025, an estimated 42,680 people (42,170 women and 510 men) will die from the disease. […] The five- and 10-year relative survival rates for women with invasive breast cancer are 91 percent and 84 percent, respectively. […] The overall five-year relative survival rate is 99 percent for localized disease, 86 percent for regional disease, and 30 percent for distant-stage disease. […] Since 1975, the breast cancer five-year relative survival rate has increased significantly for both black and white women. While a substantial gap remains, especially for late-stage diagnoses, the racial disparity seems to be narrowing. In the most recent period, the five-year relative survival rate was 83 percent for black women and 92 percent for white women.

• #106 Breast Cancer Facts & Stats 2024 – Incidence, Age, Survival, & More

  https://www.nationalbreastcancer.org/breast-cancer-facts/

  1 in 8 women in the United States will be diagnosed with breast cancer in her lifetime. In 2025, an estimated 316,950 women and 2,800 men will be diagnosed with invasive breast cancer, and an additional 59,080 new cases of non-invasive (in situ) breast cancer will be diagnosed. […] When caught in its earliest, localized stages, the 5-year relative survival rate is 99%. Advances in early detection and treatment methods have significantly increased breast cancer survival rates in recent years, and there are currently over 4 million breast cancer survivors in the United States. […] The early detection of breast cancer through annual mammography and other breast exams is the best defense against receiving a late-stage breast cancer diagnosis. Generally speaking, the earlier the cancer is detected, the greater the likelihood of a successful outcome.

• #107 Breast Cancer Facts & Stats 2024 – Incidence, Age, Survival, & More

  https://www.nationalbreastcancer.org/breast-cancer-facts/

  1 in 8 women in the United States will be diagnosed with breast cancer in her lifetime. In 2025, an estimated 316,950 women and 2,800 men will be diagnosed with invasive breast cancer, and an additional 59,080 new cases of non-invasive (in situ) breast cancer will be diagnosed. […] When caught in its earliest, localized stages, the 5-year relative survival rate is 99%. Advances in early detection and treatment methods have significantly increased breast cancer survival rates in recent years, and there are currently over 4 million breast cancer survivors in the United States. […] The early detection of breast cancer through annual mammography and other breast exams is the best defense against receiving a late-stage breast cancer diagnosis. Generally speaking, the earlier the cancer is detected, the greater the likelihood of a successful outcome.

• #108 HER2-positive Breast Cancer Epidemiology | Oncology Nurses Quality Improvement Series

  https://oncologynurse-ce.com/her2-positive-breast-cancer-epidemiology/

  In comparison of different subtypes, HER2+ breast cancers only constitute 14% of all female breast cancer cases. […] Survival rates for HER2+ breast cancers can vary by subtype: The 5-year relative survival of patients with HR+/HER2+ breast cancers is 90.4%, the second-best survival of all women with breast cancer. […] Although this subtype is the least common, the 5-year relative survival of patients with HR-/HER2+ breast cancers is 83.6%. […] Staging of disease can significantly impact 5-year relative survival rates: Relative survival of HR+/HER2+ breast cancer patients is 98.7% if disease is localized, 89.5% if disease is regional and 43.5% if disease is distant. […] Similarly, relative survival of HR-/HER2+ breast cancer patients is 96.1% if disease is localized, 81.7% if disease is regional and 36.8% if disease is distant.

• #109 HER2-positive Breast Cancer Epidemiology | Oncology Nurses Quality Improvement Series

  https://oncologynurse-ce.com/her2-positive-breast-cancer-epidemiology/

  In comparison of different subtypes, HER2+ breast cancers only constitute 14% of all female breast cancer cases. […] Survival rates for HER2+ breast cancers can vary by subtype: The 5-year relative survival of patients with HR+/HER2+ breast cancers is 90.4%, the second-best survival of all women with breast cancer. […] Although this subtype is the least common, the 5-year relative survival of patients with HR-/HER2+ breast cancers is 83.6%. […] Staging of disease can significantly impact 5-year relative survival rates: Relative survival of HR+/HER2+ breast cancer patients is 98.7% if disease is localized, 89.5% if disease is regional and 43.5% if disease is distant. […] Similarly, relative survival of HR-/HER2+ breast cancer patients is 96.1% if disease is localized, 81.7% if disease is regional and 36.8% if disease is distant.

• #110

  https://www.who.int/news-room/fact-sheets/detail/breast-cancer

  Family history of breast cancer increases the risk of breast cancer, but most women diagnosed with breast cancer do not have a known family history of the disease. […] Certain inherited high penetrance gene mutations greatly increase breast cancer risk, the most dominant being mutations in the genes BRCA1, BRCA2 and PALB-2. […] The objective of the WHO Global Breast Cancer Initiative (GBCI) is to reduce global breast cancer mortality by 2.5% per year, thereby averting 2.5 million breast cancer deaths globally between 2020 and 2040.

• #111 The Epidemiology of Breast Cancer – Breast Cancer – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK583819/

  In the developing world, women have a 17% higher BC mortality rate due to a lack of defined early screening standards and poor or delayed access to treatment. […] The highest 5-year survival rate (99.1%) in the USA is seen in BC cases with tumors localized to the initial place of origin. […] The 5-year survival rate from 2012 to 2018 was 90.6%. […] According to the American Cancer Society, 43,250 women and 530 men are expected to die from BC in 2022, while the projected 2040 BC mortality is expected to decrease to 30,000 deaths. […] Overall, the incidence of breast cancer has doubled in the last few decades in 60/102 countries, including Argentina, Brazil, and Afghanistan. […] Better organized screening programs, establishment of breast cancer registries, and more widespread use of mammography screening in lower developmental regions of the world can increase early-stage breast cancer diagnosis, reduce breast cancer-related mortality, and help reduce future global breast cancer burden.

• #112 What CDC Is Doing About Breast Cancer | Breast Cancer | CDC

  https://www.cdc.gov/breast-cancer/what-cdc-is-doing/index.html

  National Health Interview Survey (NHIS): This survey collects information about a broad range of health topics, including information about breast cancer screening and risk factors for breast cancer. […] CDC’s Division of Cancer Prevention and Control supports studies that help improve efforts to prevent and control breast cancer. […] CDC’s National Breast and Cervical Cancer Early Detection Program provides quality breast and cervical cancer screening and diagnostic services to women with low incomes who are uninsured and underserved, and supports strategies to increase screening in health systems and communities.

• #113 What CDC Is Doing About Breast Cancer | Breast Cancer | CDC

  https://www.cdc.gov/breast-cancer/what-cdc-is-doing/index.html

  National Health Interview Survey (NHIS): This survey collects information about a broad range of health topics, including information about breast cancer screening and risk factors for breast cancer. […] CDC’s Division of Cancer Prevention and Control supports studies that help improve efforts to prevent and control breast cancer. […] CDC’s National Breast and Cervical Cancer Early Detection Program provides quality breast and cervical cancer screening and diagnostic services to women with low incomes who are uninsured and underserved, and supports strategies to increase screening in health systems and communities.

• #114 What CDC Is Doing About Breast Cancer | Breast Cancer | CDC

  https://www.cdc.gov/breast-cancer/what-cdc-is-doing/index.html

  CDC is working to prevent and control breast cancer in several ways. […] The ASTHO Breast Cancer Disparities Online Toolkit provides resources for identifying, measuring, and addressing disparities in avoidable deaths from breast cancer among different groups of women. […] Cancer surveillance is the collection of information about cancer, including: Which groups of people were diagnosed with breast cancer. […] This information allows scientists to: See how breast cancer rates change over time and whether more women are being diagnosed before their cancer has spread. […] CDC supports cancer surveillance through: National Program of Cancer Registries: Funded by CDC, this program collects information about cancers diagnosed in the United States through central cancer registries. […] The BRFSS also collects information about breast cancer screening.

• #115 Cancer Surveillance and Health Services Research (SHSR) | American Cancer Society

  https://www.cancer.org/research/surveillance-and-health-equity-science/surveillance-research.html

  Identify and track emerging trends and inequalities in cancer occurrence and outcomes. […] Contribute to the advancement of surveillance research through scientific publications, conference participation, and collaborations across institutions and disciplines. […] Each year, we produce the ACS flagship report, Cancer Facts Figures, along with its companion article, Cancer Statistics, published in the ACS scientific journal CA: A Cancer Journal for Clinicians. […] These widely cited reports present the most current rates and trends in cancer incidence, mortality, and survival, as well as the most up-to-date information on symptoms, prevention, early detection, and treatment. […] The Surveillance team analyzes and interprets data to produce the ACS Facts Figures. Find the latest information including the most current trends in cancer occurrence survival, as well as information on prevention, early detection, treatment. […] Our team’s epidemiologists regularly update multiple Cancer Facts Figures reports and an interactive statistics website. We also publish additional cancer surveillance research, and we provide statistical support internally and externally.

• #116 Breast Cancer — Cancer Epidemiology Unit (CEU)

  https://www.ceu.ox.ac.uk/research/breast-cancer

  Breast cancer is the most common cancer in women worldwide and its incidence is increasing. The Cancer Epidemiology Unit has a long-established and substantial programme of research aimed at improving our understanding of the aetiology of the disease, and informing public health policy on breast cancer prevention. […] The Million Women Study has also been a rich source of information on the role of other modifiable risk factors in the development of breast cancer such as alcohol consumption (Allen et al, 2009), adiposity (Reeves et al, 2007) and childbearing (Beral et al, 2002). […] The study was also among the first to report on the predictive value of a polygenic risk score for breast cancer showing that such a score was more predictive for hormone sensitive disease (Reeves et al, 2010).

• #117 Breast Cancer — Cancer Epidemiology Unit (CEU)

  https://www.ceu.ox.ac.uk/research/breast-cancer

  Breast cancer is the most common cancer in women worldwide and its incidence is increasing. The Cancer Epidemiology Unit has a long-established and substantial programme of research aimed at improving our understanding of the aetiology of the disease, and informing public health policy on breast cancer prevention. […] The Million Women Study has also been a rich source of information on the role of other modifiable risk factors in the development of breast cancer such as alcohol consumption (Allen et al, 2009), adiposity (Reeves et al, 2007) and childbearing (Beral et al, 2002). […] The study was also among the first to report on the predictive value of a polygenic risk score for breast cancer showing that such a score was more predictive for hormone sensitive disease (Reeves et al, 2010).

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