Keratitis
Zapobieganie i profilaktyka
Zapalenie rogówki (keratitis) stanowi poważne zagrożenie dla wzroku, szczególnie u użytkowników soczewek kontaktowych, u których ryzyko rozwoju keratitis wzrasta 5-10-krotnie, zwłaszcza przy noszeniu soczewek przez całą noc lub dłuższy czas. Profilaktyka obejmuje rygorystyczne przestrzeganie higieny rąk, właściwe czyszczenie i dezynfekcję soczewek oraz pojemników, unikanie kontaktu soczewek z wodą oraz stosowanie soczewek jednodniowych. Regularne badania okulistyczne i natychmiastowa konsultacja w przypadku objawów podrażnienia są kluczowe. W przypadku wirusowego zapalenia rogówki wywołanego przez HSV, doustna profilaktyka acyklowirem w dawce 400 mg raz lub dwa razy dziennie może zmniejszyć nawroty o 50%, choć nie eliminuje całkowicie ryzyka. W profilaktyce pooperacyjnej po zabiegach takich jak LASIK zaleca się stosowanie fluorchinolonów IV generacji (gatifloksacyna 0,3%, moksyfloksacyna 0,5%) oraz dezynfekcję powiek 10% roztworem betadyny.
- Zapalenie rogówki (Keratitis) – wprowadzenie
- Ogólne zasady profilaktyki zapalenia rogówki
- Profilaktyka keratitis u użytkowników soczewek kontaktowych
- Profilaktyka wirusowego zapalenia rogówki
- Profilaktyka keratitis wywołanej przez Acanthamoeba
- Profilaktyka pourazowa zapalenia rogówki
- Profilaktyka zapalenia rogówki po zabiegu LASIK
- Profilaktyka polekowego zapalenia rogówki
- Specjalne sytuacje profilaktyczne
- Profilaktyka keratitis ekspozycyjnego
- Profilaktyka photokeratitis (zapalenia rogówki spowodowanego promieniowaniem UV)
- Nowe kierunki w profilaktyce keratitis
- Znaczenie profilaktyki keratitis
Zapalenie rogówki (Keratitis) – wprowadzenie
Zapalenie rogówki (keratitis) to stan zapalny rogówki, przezroczystej przedniej części oka. Nieleczone zapalenie rogówki może prowadzić do trwałego uszkodzenia wzroku lub nawet ślepoty, dlatego profilaktyka i wczesne leczenie mają kluczowe znaczenie dla zachowania prawidłowego widzenia123. Najczęstszym czynnikiem ryzyka rozwoju keratitis jest noszenie soczewek kontaktowych, szczególnie przy ich niewłaściwym używaniu lub konserwacji4. Działania zapobiegawcze mają kluczowe znaczenie, gdyż umożliwiają redukcję liczby zachorowań oraz zmniejszenie nasilenia infekcji5.
Ogólne zasady profilaktyki zapalenia rogówki
Profilaktyka keratitis powinna obejmować działania zmniejszające ryzyko wystąpienia zarówno infekcyjnych, jak i nieinfekcyjnych form tego schorzenia. Podstawowe zalecenia obejmują16:
- Regularne badania okulistyczne, umożliwiające wczesne wykrycie problemów z oczami
- Dokładne mycie rąk przed dotykaniem oczu
- Unikanie dotykania oczu podczas choroby
- Noszenie okularów ochronnych podczas pracy i aktywności sportowych
- Stosowanie okularów przeciwsłonecznych chroniących oczy przed promieniowaniem UV
- Dieta bogata w witaminę A, pomagająca zapobiegać keratitis z niedoboru witaminy A
- Natychmiastowe zgłoszenie się do lekarza w przypadku objawów podrażnienia oka
Profilaktyka keratitis u użytkowników soczewek kontaktowych
Noszenie soczewek kontaktowych zwiększa ryzyko zapalenia rogówki 5-10-krotnie, szczególnie przy ich noszeniu przez całą noc lub przez wydłużony czas9. Przestrzeganie poniższych zasad może znacząco zmniejszyć ryzyko wystąpienia keratitis1011:
Prawidłowe noszenie soczewek
- Czas noszenia – przestrzeganie zalecanego przez lekarza okulistę czasu noszenia soczewek
- Soczewki dzienne – wybór soczewek jednodniowych i wyjmowanie ich przed snem
- Zdejmowanie soczewek – przed kąpielą, pływaniem, korzystaniem z jacuzzi czy prysznica
- Natychmiastowe zdejmowanie – w przypadku dyskomfortu, zaczerwienienia, bólu lub niewyraźnego widzenia
- Posiadanie okularów zapasowych – w przypadku problemów z soczewkami
Higiena i czyszczenie soczewek
- Mycie rąk – dokładne mycie, płukanie i suszenie rąk przed dotykaniem soczewek lub oczu
- Czyszczenie soczewek – czyszczenie, pocieranie i płukanie soczewek przy każdym wyjmowaniu
- Stosowanie odpowiednich płynów – używanie wyłącznie sterylnych produktów przeznaczonych specjalnie do danego typu soczewek
- Wymiana płynu – wyrzucanie roztworu z pojemnika na soczewki przy każdej dezynfekcji; unikanie „dolewania” świeżego roztworu do starego
- Unikanie wody – nigdy nie używać wody z kranu, butelkowanej ani śliny do przechowywania lub płukania soczewek
Wymiana soczewek i pojemników
- Regularna wymiana soczewek – zgodnie z zaleceniami specjalisty
- Wymiana pojemnika – co 3-6 miesięcy
- Czyszczenie pojemnika – utrzymywanie pojemnika na soczewki w czystości i dezynfekcja zgodnie z zaleceniami
- Suszenie pojemnika – płukanie pojemnika płynem do soczewek i suszenie czystą chusteczką
Badania pokazują, że przestrzeganie tych zaleceń może zmniejszyć obciążenie chorobą o 60-70% poprzez unikanie noszenia soczewek przez całą noc i zwracanie uwagi na czynniki higieniczne18. Szczególną uwagę należy zwrócić na higienę pojemnika na soczewki, ponieważ zarówno jego czyszczenie, jak i wymiana zmniejszają ryzyko ciężkiej choroby przy codziennym noszeniu soczewek18.
Profilaktyka wirusowego zapalenia rogówki
Pewne formy wirusowego zapalenia rogówki, szczególnie spowodowane przez wirusa opryszczki pospolitej (HSV), nie mogą być całkowicie wyeliminowane, ale można kontrolować ich występowanie poprzez1920:
- Higiena rąk – częste mycie rąk może zmniejszyć częstość występowania ognisk wirusowych
- Unikanie dotykania oczu – jeśli masz opryszczkę lub pęcherz opryszczki, unikaj dotykania oczu, powiek i skóry wokół oczu, chyba że dokładnie umyjesz ręce
- Stosowanie tylko przepisanych kropli – używaj wyłącznie kropli do oczu przepisanych przez lekarza okulistę
Profilaktyka farmakologiczna HSV keratitis
Badania Herpetic Eye Disease Study (HEDS) wykazały, że długotrwała profilaktyka doustnymi lekami przeciwwirusowymi może zmniejszyć nawroty o 50%2223. Dla pacjentów z nawracającym HSV keratitis zaleca się2423:
- Acyklowir 400 mg – przyjmowany raz lub dwa razy dziennie jako profilaktyka może zmniejszyć częstość nawrotów
- Długotrwała profilaktyka – zalecana dla pacjentów z nawracającą chorobą stromalną lub więcej niż 2 epizodami choroby nabłonkowej rocznie
- Profilaktyka przed zabiegami chirurgicznymi – u pacjentów z historią HSV zaleca się profilaktykę przeciwwirusową jeden lub kilka dni przed zabiegiem, połączoną z pooperacyjnym stosowaniem przez kilka tygodni
Należy pamiętać, że mimo skuteczności doustnej profilaktyki przeciwwirusowej, przełom keratitis spowodowany przez HSV może nadal wystąpić. HEDS wykazało 50% zmniejszenie występowania opryszczki ocznej, a nie 100% eliminację23.
Profilaktyka keratitis wywołanej przez Acanthamoeba
Zapalenie rogówki wywołane przez Acanthamoeba (AK) jest rzadkim, ale poważnym zakażeniem, które może prowadzić do utraty wzroku. Ponieważ leczenie jest toksyczne, długotrwałe i nie zawsze skuteczne, profilaktyka ma kluczowe znaczenie2526.
Oprócz ogólnych zasad higieny soczewek kontaktowych, szczególnie ważne w profilaktyce AK są2728:
- Unikanie wody – nigdy nie używać wody z kranu do płukania lub przechowywania soczewek
- Unikanie pływania – nie nosić soczewek podczas pływania, kąpieli, prysznica lub korzystania z jacuzzi
- Odpowiednie środki dezynfekujące – dwuetapowe roztwory zawierające nadtlenek wodoru są skuteczne zarówno przeciwko trofozoitom, jak i cystom Acanthamoeba
- Przechowywanie poza łazienką – rozważenie przechowywania soczewek poza łazienką, aby zmniejszyć ryzyko zanieczyszczenia wodą
- Ochrona oczu – dodatkowa ostrożność u osób z problemami z układem odpornościowym lub urazami oka
Ostatnie badania nad nowymi związkami skutecznymi przeciwko zarówno trofozoitom, jak i cystom Acanthamoeba dają nadzieję na opracowanie bardziej efektywnych metod zapobiegania AK33.
Profilaktyka pourazowa zapalenia rogówki
Urazy rogówki zwiększają ryzyko rozwoju zakażenia. Wtórna profilaktyka (zapobieganie uszkodzeniu wzroku u osoby z urazem rogówki) może być najlepszą opcją zmniejszenia utraty wzroku związanej z zapaleniem rogówki534.
- Wczesne leczenie otarć – badania w Azji Południowo-Wschodniej wykazały, że maść przeciwdrobnoustrojowa zastosowana wkrótce po otarciu rogówki może dramatycznie zmniejszyć częstość występowania zapalenia rogówki
- Profilaktyka antybiotykowa – po zidentyfikowaniu otarcia rogówki, maści antybiotykowe i przeciwgrzybicze powinny być stosowane trzy razy dziennie przez 3 dni, aby zapobiec infekcji
- Antybiotyki po urazie – miejscowe antybiotyki są rutynowo podawane po urazie rogówki (w tym po operacji)
Profilaktyka zapalenia rogówki po zabiegu LASIK
Aby zapobiec pooperacyjnemu keratitis po zabiegu LASIK, chirurdzy powinni wdrożyć kilka kroków36:
- Badanie przedoperacyjne – dokładne badanie powiek i aparatu łzowego przed zabiegiem refrakcyjnym
- Leczenie infekcji powiek – przed LASIK-iem z pomocą ciepłych kompresów i miejscowej maści antybiotykowej nakładanej trzy razy dziennie na brzeg powieki
- Dezynfekcja przedoperacyjna – stosowanie 10% roztworu betadyny na powieki przed zabiegiem
- Sterylne płyny – wszystkie płyny stosowane na oko przed, w trakcie i po LASIK-u powinny być dezynfekowane
- Antybiotyki profilaktyczne – fluorchinolony czwartej generacji (gatifloksacyna 0,3% i moksyfloksacyna 0,5%) są zalecane do profilaktyki antybiotykowej przeciwko infekcji po LASIK-u i PRK
Aktywne zapalenie rogówki HSV jest bezwzględnym przeciwwskazaniem do laserowej chirurgii refrakcyjnej rogówki (tj. LASIK, PRK) lub innych zabiegów na rogówce (cross-linking kolagenu). Nieaktywne zapalenie rogówki lub historia poprzedniej choroby HSV również jest uważana za względne przeciwwskazanie38.
Profilaktyka polekowego zapalenia rogówki
Profilaktyka keratitis po cytarabinie
Toksyczność rogówki po wysokich dawkach cytarabiny jest dobrze ustalonym ryzykiem terapii. Rutynowa profilaktyka z kroplami do oczu, zwykle miejscowymi kroplami kortykosteroidowymi, jest ustaloną częścią protokołów leczenia wysokimi dawkami cytarabiny39.
- Profilaktyka kortykosteroidami – krople do oczu zawierające kortykosteroidy są zalecane przy dawkach cytarabiny >1000 mg/m²
- Częste stosowanie – podawanie co 4 lub 6 godzin według ścisłego harmonogramu zapewnia największe korzyści
- Czas trwania – krople należy kontynuować co najmniej 48 godzin po ostatniej dawce cytarabiny
- Dodatkowe opcje – roztwory zastępujące łzy oraz miejscowe, niesteroidowe krople przeciwzapalne (NLPZ)
Bez profilaktyki miejscowymi kortykosteroidami częstość występowania keratoconjunctivitis wynosi 85% do 100% przypadków; przy stosowaniu profilaktyki, klinicznie istotne objawy występują w 8% do 16% przypadków39.
Specjalne sytuacje profilaktyczne
Profilaktyka keratitis ekspozycyjnego
Keratitis ekspozycyjne występuje, gdy powieki nie zamykają się prawidłowo, pozostawiając rogówkę narażoną na wysychanie. Jest to powszechne u pacjentów na oddziałach intensywnej terapii (OIOM). Potencjalnie zagrażające wzrokowi zaburzenia powierzchni oka stwierdzono u ponad 50% pacjentów OIOM40.
- Sztuczne łzy – krople i maści do oczu pomagają utrzymać wilgotność oczu
- Ochronne soczewki kontaktowe – silikonowo-hydrożelowe soczewki opatrunkowe lub skleralne mogą chronić rogówkę
- Okulary ochronne – mogą być używane do ochrony rogówki
- Tarsorrhafia – tymczasowa lub stała może być wskazana w leczeniu niedomykalności powiek
- Ciężarki – złote ciężarki mogą być wszczepione do górnej powieki w leczeniu porażenia nerwu twarzowego
Profilaktyka photokeratitis (zapalenia rogówki spowodowanego promieniowaniem UV)
Photokeratitis to stan zapalny rogówki spowodowany ekspozycją na intensywne promieniowanie UV. Noszenie odpowiedniej ochrony oczu i zabezpieczenie oczu przed słońcem i promieniowaniem UV jest kluczem do zapobiegania photokeratitis42.
- Okulary przeciwsłoneczne – blokujące lub pochłaniające co najmniej 99% promieni ultrafioletowych
- Gogle śnieżne – przy ekspozycji na słońce lub śnieg
- Kapelusz – z daszkiem lub szerokim rondem, aby dodatkowo chronić oczy
- Kask spawacza – pełna osłona twarzy z regulowanym poziomem zaciemnienia
- Soczewki kontaktowe pochłaniające UV – dostępne dla osób spędzających dużo czasu na zewnątrz
Nowe kierunki w profilaktyce keratitis
Badania nad nowymi metodami profilaktyki i leczenia keratitis są prowadzone w kilku obszarach4333:
- Terapia światłem UV – szczególnie UVC, jako obiecujący dodatek lub alternatywa dla konwencjonalnych antybiotyków ze względu na szerokie spektrum przeciwdrobnoustrojowe i mechanizm niezależny od oporności
- Sztuczne łzy z działaniem przeciw Acanthamoeba – badania in vitro wykazały, że niektóre formuły sztucznych łez, szczególnie zawierające BAK (chlorek benzalkoniowy), mają znaczący i trwały efekt amebobójczy
- Nowe związki przeciwko Acanthamoeba – skuteczne zarówno przeciwko trofozoitom, jak i cystom, dające nadzieję na opracowanie nowych metod zapobiegania AK
- Szczepionki przeciwko HSV – trwają badania, które choć skupiają się głównie na HSV-2 i opryszczce narządów płciowych, mogą oferować ochronę krzyżową w zapobieganiu ocznym infekcjom HSV-1
Znaczenie profilaktyki keratitis
Zapalenie rogówki może szybko postępować i prowadzić do trwałego uszkodzenia wzroku, dlatego profilaktyka ma kluczowe znaczenie45. Odpowiednia higiena oczu, prawidłowe używanie i pielęgnacja soczewek kontaktowych oraz szybka reakcja na pierwsze objawy mogą znacząco zmniejszyć ryzyko rozwoju keratitis46.
Dla użytkowników soczewek kontaktowych, przestrzeganie zasad higieny i pielęgnacji może zmniejszyć obciążenie chorobą o 60-70%18. Dla pacjentów z nawracającym HSV keratitis, profilaktyka przeciwwirusowa może zmniejszyć nawroty o 50%22.
Wczesna interwencja, szczególnie w przypadku urazów rogówki, może zapobiec rozwojowi zakażenia5. Wszystkie te działania profilaktyczne mają na celu zmniejszenie obciążenia związanego z keratitis i zachowanie zdrowego wzroku34.
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Materiały źródłowe
- #1 Keratitis: Types, Symptoms & Treatmenthttps://my.clevelandclinic.org/health/diseases/24500-keratitis
Keratitis can be divided into two categories based on cause: infectious keratitis or noninfectious keratitis. […] You can reduce your risk of developing keratitis by: Following instructions on how long to wear your contact lenses. Making sure your hands are clean if you have to touch your eyes. Following instructions on cleaning and sanitizing your contact lenses. Not swimming, showering or using the hot tub when you’re wearing your contact lenses. Practicing good hand washing techniques and avoiding contact with people who are sick. Wearing protective eyewear while working and participating in sports. Wearing sunglasses to protect your eyes from UV light. […] One major risk factor for keratitis is wearing contact lenses. This is related to: Wearing them longer than you’re supposed to wear them. This can cause damage to your eye and possibly allow infection to enter. Not cleaning / disinfecting them properly. Wearing them while you’re in pools, hot tubs or outdoor water sources.
- #2 Keratitis | AOAhttps://www.aoa.org/healthy-eyes/eye-and-vision-conditions/keratitis
Keratitis can cause serious complications and may permanently damage your vision. […] To prevent keratitis, contact lens wearers should follow the wearing schedule and care regimen prescribed by their eye doctor. Do not sleep in lenses unless recommended by a doctor of optometry. Do not swim in contact lenses and always wash hands before handling lenses. If experiencing redness, pain or blurry vision, remove the contact lenses and contact your doctor of optometry.
- #3 What Causes Bacterial Keratitis | Healthy Contact Lens Wear and Care | CDChttps://www.cdc.gov/contact-lenses/causes/what-causes-contact-lens-related-bacterial-keratitis.html
If bacterial keratitis is left untreated, it can lead to vision loss or even blindness. […] If you experience unusual eye irritation, promptly remove your contact lenses. Avoid wearing contact lenses again until advised by your eye doctor. […] Contact lenses are medical devices, and failure to wear, clean, and store them as directed can increase the risk of eye infections, such as microbial keratitis.
- #4 Keratitis: Types, symptoms, and treatmenthttps://www.medicalnewstoday.com/articles/320347
The most common cause of keratitis is contact lens use. Proper cleaning, storage, and use are crucial. Anyone who wears contacts can help prevent keratitis by: […] Overall, the best way to prevent keratitis is to keep the hands and area around the eyes clean and avoid touching the eyes.
- #5 Microbial keratitis: a community eye health approachhttps://pmc.ncbi.nlm.nih.gov/articles/PMC4579989/
Microbial keratitis is an infection of the cornea. Corneal opacities, which are frequently due to microbial keratitis, remain among the top five causes of blindness worldwide. […] Given the limitations associated with available treatment options, secondary prevention (i.e. the prevention of visual impairment in someone with a corneal injury and/or infection) may be the best option for reducing vision loss associated with microbial keratitis. […] A series of studies in Southeast Asia suggested that antimicrobial ointment applied soon after a corneal abrasion could dramatically reduce the incidence of microbial keratitis. […] These studies demonstrated that village health workers can be trained to diagnose corneal abrasions and provide prophylactic treatment, and suggested that this simple intervention might be effective. […] Prophylaxis. Once a corneal abrasion is identified, antibiotic and antifungal ointments should be applied three times a day for 3 days to prevent infection. […] In low- and middle-income countries, the prevention of microbial keratitis is a promising intervention for reducing corneal blindness.
- #6 What is Keratitis? Causes, Treatment and Preventionhttps://www.nvisioncenters.com/conditions/keratitis/
Keratitis can get worse with time, eventually leading to blindness. For this reason, as with most eye conditions, see a doctor immediately if you suspect a problem. The faster you get treatment, the less likely you are to experience serious and long-lasting complications. […] Keratitis is caused by infection or injury. Apart from viral keratitis, its possible to avoid other forms of the condition by practicing proper eye and contact lens hygiene. Keratitis can also affect people who dont wear contacts as it can result from trauma or physical injury. Here are a few ways you can protect your eyes: Always wear protective eye gear when working with plants, trees, or lumber. Avoid excess UV light exposure by wearing sunglasses. Being aware of your allergens and avoiding them, if possible. Eating a diet rich in Vitamin A to prevent Vitamin A deficiency keratitis.
- #7 Keratitis Symptoms, Treatments, and Prevention | LifeMDhttps://lifemd.com/learn/keratitis-symptoms-treatments-and-prevention
Wash your hands thoroughly with soap and water before handling your contact lenses. […] Regularly clean and replace your contact lens cases. Use sterile solutions to clean them and let the case air dry. […] Dont wear contact lenses for longer than recommended, and avoid sleeping while wearing them unless designed for overnight use. […] Wear protective goggles or glasses when doing activities that could result in eye injury, such as sports, construction work, or handling chemicals. […] Schedule regular eye examinations with an eye care professional to detect and address any issues early on. […] To prevent pathogens from entering the eye, try not to touch or rub the eyes excessively, especially with unwashed hands. This is especially important if you have a cold sore or herpes blister.
- #8 How to Treat Keratitis: Effective Care and Prevention Tipshttps://nextcare.com/health-resources/treat-keratitis-care-and-prevention/
Dealing with a painful or irritated eye can be really worrisome. If youâre experiencing these symptoms, you may be wondering how to treat keratitis. Keratitis is an eye disease that involves inflammation of the cornea â the transparent front part of your eye. Learning how to treat keratitis quickly can help prevent complications and preserve your vision. […] Youâll also learn about preventive measures to minimize your chances of encountering this eye condition. […] By adopting a few preventive measures, you can reduce your risk factor for developing this condition: […] When wearing contact lenses, proper handling and hygiene become especially crucial for preventing keratitis: […] Here are additional ways to prioritize eye health and minimize your chances of developing keratitis: […] Regular Eye Exams: Visiting your eye doctor for routine checkups is paramount. Early detection and intervention play a significant role in preventing irreversible vision issues.
- #9 Centre for Health Protection – Prevention of Microbial Keratitis in Contact Lens Wearershttps://www.chp.gov.hk/en/healthtopics/content/24/11201.html
Keratitis is an inflammation of the cornea, which is the transparent front part of the eye. […] Wearing contact lens is associated with increased risk of keratitis. The risk of microbial keratitis is increased by five to ten-fold among those who wear lens overnight and for prolonged period of time. […] To prevent contact lens related microbial keratitis, contact lens wearers should take heed of the health advice below: Regularly have your eyes checked by eye care professionals. Remove the contact lens whenever you feel discomfort (e.g. redness, pain, tearing or blurred vision) and seek medical advice promptly if symptoms persist despite the contact lenses have been taken off. Never share contact lenses. When using contact lens solution, follow the manufacturers instructions for use. Keep all accessories used for cleansing and disinfecting contact lenses (e.g. contact lens storage case) clean and replace them regularly.
- #10 Keratitis – Symptoms and causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/keratitis/symptoms-causes/syc-20374110
If you wear contact lenses, proper use, cleaning and disinfecting can help prevent keratitis. Follow these tips: […] Choose daily wear contacts and take them out before going to sleep. […] Wash, rinse and dry your hands thoroughly before handling your contacts. […] Follow your eye care provider’s recommendations for taking care of your lenses. […] Use only sterile products that are made specifically for contact lens care, and use lens care products made for the type of lenses you wear. […] Replace your contact lenses as recommended. […] Replace your contact lens case every 3 to 6 months. […] Discard the solution in the contact lens case each time you disinfect your lenses. Don’t „top off” the old solution that’s already in the case. […] Don’t wear contact lenses when you go swimming.
- #11 Explains Keratitis, an inflammation of the cornea – Prevent Blindnesshttps://preventblindness.org/keratitis/
If you are sick, wash your hands often and try not to touch your eyes. […] Wear proper eye protection if you are looking at intense UV light. And if you wear contact lenses, handle and care for them correctly: […] Follow your eye doctors recommendations for taking care of your contact lenses […] Wash your hands and make sure they are completely dry before touching your contact lenses or your eyes […] Always use fresh solution to clean and store your contact lenses […] Keep the area where you store and keep your contact lenses and contact lens case clean and germ free […] Never store contact lenses in tap water […] Do not sleep in contact lenses when you are supposed to take them out every night […] Do not swim or shower in your contact lenses […] Replace your contact lenses and contact lens storage case as recommended.
- #12 Acanthamoeba Keratitis: Symptoms, Treatment & Preventionhttps://my.clevelandclinic.org/health/diseases/21560-acanthamoeba-keratitis
Can acanthamoeba keratitis be prevented? […] AK is mostly preventable, though uncommon cases can happen for reasons you cant control. Steps you can take include: […] Wear contact lenses as instructed. Dont wear your contacts for too long, leave them in overnight or wear them while swimming or showering. […] Store your contacts properly. Never use anything but contact lens solution to store your contacts when you take them out. Your eye care specialist can tell you more about the right kind of solution to use. […] Clean your contacts and the case you store them in. Contact lens solution usually doesnt disinfect your lenses. Your eye care specialist can tell you how to sanitize your contacts and contact lens case, and how often you need to do this. […] Throw contacts away if you get an eye infection and replace the case. Reusing contaminated contacts or contact lens cases can cause reinfection.
- #13 Acanthamoeba Keratitis | Acanthamoeba Infections | CDChttps://www.cdc.gov/acanthamoeba/about/about-acanthamoeba-keratitis.html
Proper contact lens care can help reduce the risk of Acanthamoeba keratitis. […] To protect against Acanthamoeba keratitis and other eye infections, contact lens wearers should follow healthy habits, including: […] Washing your hands with soap and water and drying them before handling contacts. […] Removing contact lenses before showering, using a hot tub, or swimming. […] Cleaning, rubbing, and rinsing lenses every time you take them out. […] Storing lenses properly.
- #14 Acanthamoeba Keratitis And How To Prevent It | Eye Clinichttps://www.eyecliniclondon.com/blog/acanthamoeba-keratitis-prevent/
Acanthamoeba keratitis is an eye infection that is rare but serious, mostly affecting people who wear contact lenses, but it can affect anyone. […] Trying to prevent this infection is always best as it can be very difficult to treat once it has been contracted, and some infections can be so serious that the only option is to have a corneal transplant. […] Here are 7 top tips on the best ways to reduce the chance of getting acanthamoeba keratitis if you wear contact lenses. […] Always visit your eye clinic for regular eye checks. […] Before you touch your contact lenses, always make sure you have clean dry hands. […] Never use tap water to wash or keep your contact lenses in, only use the recommended solution. […] For wearers of monthly contact lenses, always wash them as soon as they have been removed in the recommended solution, and always store them in a clean case that has been filled with fresh disinfectant solution, never âtop upâ older solution with fresh solution.
- #15 Keratitis Symptoms, Treatments, and Prevention | LifeMDhttps://lifemd.com/learn/keratitis-symptoms-treatments-and-prevention
Keratitis can result from infections and injuries, making it important to recognize the symptoms and seek early medical treatment. […] In this article, well discuss the main causes and symptoms of keratitis should you be worried about this condition. Well also share how you can prevent developing keratitis. […] Using contact lenses for too long or not cleaning them properly can also cause injury to the cornea and lead to infectious keratitis. […] Not cleaning or storing contact lenses correctly can lead to bacterial contamination. As mentioned above, these bacteria can adhere to the surfaces of contact lenses and cause bacterial keratitis. […] There are some practical steps you can take to ensure you dont develop keratitis: […] Always use solutions designed for contact lenses to clean, rinse, and store contact lenses. Avoid using tap water or homemade solutions.
- #16 Keratitis – Health Tips, Keratitis Health Articles, Health News | TheHealthSite.comhttps://www.thehealthsite.com/diseases-conditions/keratitis/
The following measures can prevent the occurrence of keratitis: […] Wash your hands thoroughly before handling contact lenses, solutions or related accessories […] Clean and disinfect the contact lens properly before and after use […] Have routine check-ups by an ophthalmologist and follow their medical advice […] Remove your contact lens before participating in any activity with water, including showering, swimming or using a hot tub […] If you feel discomfort or redness in the eyes, remove your contact lenses and get advice from your ophthalmologist. If symptoms persist after removing the contact lenses, consult your ophthalmologist […] Never wet your lenses with bottled water, saliva, or tap water […] Do not wear your lenses while swimming, sleeping, or taking a shower […] Avoid wearing the contact lenses for a longer time than the recommended period […] Discard the contact lenses solution after one month of use.
- #17 Keratitis: What to Do to Save Your Sighthttps://www.webmd.com/eye-health/keratitis-facts
If you’re sick, wash your hands often and try not to touch your eyes. And if you wear contacts, handle your lenses correctly: […] Don’t sleep in lenses you’re supposed to take out every day. […] Don’t swim or shower in your contacts. […] Wash your hands before touching your contacts or your eyes. […] Always use fresh solution to clean and store your lenses. […] Rinse your lens case with contact solution and dry it with a clean tissue. […] Never store contacts in tap water. […] Replace your lenses and storage case regularly.
- #18 Contact lens-related microbial keratitis: how have epidemiology and genetics helped us with pathogenesis and prophylaxis | Eyehttps://www.nature.com/articles/eye2011288
Individual differences in susceptibility to microbial keratitis may be partly explained by differences in single-nucleotide polymorphisms in certain cytokine genes, particularly those with a proven protective role in corneal infection. […] Risk factor analysis indicates that disease load is reduced by 60-70% by avoidance of overnight lens use and attention to lens hygiene factors. […] More significantly, a reduction in morbidity may be possible through recognition of appropriate risk factors, such as hygiene, specifically attention to storage case hygiene as both case cleaning and replacement reduces the risk of severe disease in daily contact lens use. […] Daily disposable lenses are associated with less severe disease. […] As the recall of these products, the rate of Acanthamoeba keratitis has remained above baseline levels, indicating the impact of as yet unidentified risk factors.
- #19 Keratitis – Symptoms and causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/keratitis/symptoms-causes/syc-20374110
Some forms of viral keratitis can’t be completely eliminated. But the following steps may control viral keratitis occurrences: […] If you have a cold sore or a herpes blister, avoid touching your eyes, your eyelids and the skin around your eyes unless you’ve thoroughly washed your hands. […] Only use eye drops that have been prescribed by an eye doctor. […] Washing your hands frequently can reduce viral outbreaks.
- #20 What is Keratitis? Causes, Treatment and Preventionhttps://www.nvisioncenters.com/conditions/keratitis/
Even though you cant completely eliminate your chances of contracting viral keratitis, its possible to reduce the risk of viral keratitis. Here are some tips: If you have a cold sore or herpes blister, minimize the instances you touch it and avoid rubbing your eyes or touching your eyelids and the skin around your eyes. Only do so when youve meticulously washed your hands. Practice proper handwashing hygiene as this goes a long way in preventing viral outbreaks. Only use eye drops primarily prescribed by a doctor.
- #21 Keratitis: Symptoms, Causes, Diagnosis and Treatment | MedPark Hospitalhttps://www.medparkhospital.com/en-US/disease-and-treatment/keratitis
Caring for your contact lenses is essential in preventing keratitis. […] Remove contact lenses before sleeping. […] Thoroughly wash, rinse, and dry your hands before handling your contact lenses. […] Follow the instructions on how to take care of your contact lenses. […] Use sterile products specifically designed for your lens type. […] Replace your contact lenses according to the recommended schedule. […] Renew your contact lens case every 3 to 6 months. […] Discard the solution in the contact lens case every time you disinfect your lenses; refrain from mixing a new solution with the old one. […] Avoid wearing contact lenses while swimming. […] While some forms of viral keratitis may not be entirely preventable, the following measures can help manage occurrences. […] Refrain from touching your eyes, eyelids, and the surrounding skin if you have a cold sore or herpes blister unless you have thoroughly washed your hands. […] Use only eye drops prescribed by an ophthalmologist. […] Frequent hand washing can help reduce viral outbreaks.
- #22 Treating HSV keratitis – EyeWorldhttps://www.eyeworld.org/2007/treating-hsv-keratitis/
Once they delineate the type of HSV keratitis the patient has, clinicians must decide on the most effective use of antiviral medications. This may mean a choice of oral versus topical antiviral medications, combining antivirals with corticosteroids when appropriate, and prescribing antiviral medications as prophylaxis indefinitely or before surgery. […] Some research, such as that from the HEDS investigators, indicates a role for oral antivirals to prevent these recurrences. […] The HEDS investigators found that long-term prophylaxis with oral antivirals can reduce recurrences by 50%. […] Dr. Chodosh recommends long-term oral acyclovir for patients with 1) multiple occurrences of HSV that each require corticosteroids, 2) recurrent inflammation with scarring or neovascularization that approaches the visual axis, 3) more than one episode of necrotizing keratitis, or 4) a history of herpetic eye disease and a corneal transplant. […] If patients with herpetic episodes must undergo eye surgery, Dr. Mah believes antiviral prophylaxis one day or a couple days before surgery, combined with post-op use for a couple of weeks, is another helpful measure.
- #23 Herpes Helperhttps://www.reviewofoptometry.com/article/herpes-helper
Antiviral prophylaxis has been used for decades in patients with herpes simplex keratitis. […] The study found an approximate 50% decrease in recurrence of ocular herpes with the one year of 400mg acyclovir used twice daily, and with no rebound effect when it was stopped for six months. […] HEDS showed effectiveness for one year, but many doctors will keep their patients on for much longer. […] Most surgeons who perform a corneal graft in an eye with herpes simplex keratitis will continue their prophylaxis for many years, if not for life, declares Dr. Rapuano. […] Clinicians must remember that while oral antiviral prophylaxis is effective, breakthrough herpes keratitis can still occur. […] HEDS demonstrated a 50% decrease in ocular herpes, not 100% elimination, Dr. Rapuano reminds.
- #24 Herpes Simplex Virus (HSV) Keratitis Treatment & Management: Approach Considerations, Infectious Epithelial Keratitis, Stromal Keratitishttps://emedicine.medscape.com/article/1194268-treatment
The major difficulties in treating herpetic keratitis relate to the tendency for recurrences and to the management of stromal disease. In its latent form, HSV can be present in the cells of the cornea and in the central connections of the trigeminal nerve, particularly in the trigeminal ganglion. Disturbance of host defense results in reactivation of the virus, its subsequent passage centrifugally along the nerve, and resultant shedding from the nerve endings. Corneal lesions occur when the balance between latency and reactivation is disturbed, such as during febrile illnesses, during menses, or on exposure to sunlight. Once trigger factors are identified, they need to be avoided. […] Using 400 mg of acyclovir once or twice daily as prophylaxis can reduce the incidence of recurrence. This is recommended for patients with recurrent stromal disease or more than 2 episodes of epithelial disease per year.
- #25 Acanthamoeba Keratitis – EyeWikihttps://eyewiki.org/Acanthamoeba_Keratitis
Since treatment is toxic, lengthy, and not necessarily effective, prevention is essential. Contact lens wearers should be taught how to clean their contact lenses properly. They should be instructed never to use tap water or even saline to clean their lenses. They should also be instructed to visit an ophthalmologist at the earliest sign of problems. […] The prognosis for Acanthamoeba is worse than for many other types of infectious keratitis and prevention is therefore very important. However, especially if caught early before the onset of stromal disease, satisfactory outcomes can certainly be achieved.
- #26 New solutions in the prevention and treatment of Acanthamoeba keratitis | Eye Newshttps://www.eyenews.uk.com/features/ophthalmology/post/new-solutions-in-the-prevention-and-treatment-of-acanthamoeba-keratitis
The global increase in Acanthamoeba keratitis infections has emphasised the inefficiencies of current treatment and preventative methods, here researchers from the West of Scotland detail a promising new series of compounds that may stem the tide. […] Here we provide an overview of recent studies on the pathogen, focusing mainly on preventative strategies developed to help reduce transmission of Acanthamoeba from the environment to the cornea through improved contact lens sterilisation. […] Acanthamoeba can come into contact with the contact lens in a variety of ways. Bathing, swimming or even rinsing lenses with tap water can provide an opportunity for the cell to attach to lenses and initiate infection. […] Consequently, these inefficiencies, coupled with the immune privilege of the eye, particularly while wearing contact lenses, means that 95% of AK cases in developed countries are associated with contact lens use.
- #27 Acanthamoeba Keratitis (AK): Treatment and Prevention Tipshttps://www.healthline.com/health/eye-health/acanthamoeba-keratitis
People who wear contacts have the highest risk of developing Acanthamoeba keratitis. Following good contact lens hygiene can minimize your chances of developing an infection. […] You can reduce your chances of developing Acanthamoeba keratitis by avoiding contaminated water or trauma to your cornea. […] If you wear contacts, you can take the following steps to decrease your risk: Store and handle your lenses properly. Wash your hands before touching your contacts. Disinfect lenses with sterile products that your eye doctor recommends. Avoid storing or washing your lenses with tap water. Avoid wearing your contacts in the shower, pool, or jacuzzi. Replace your lenses on your prescribed schedule. Avoid using other peoples lenses. Avoid sleeping with your lenses in or wearing them after swimming. Visit an eye care professional for regular checkups.
- #28 Acanthamoeba Keratitis & Contact Lenses – Prevent Blindness Iowahttps://iowa.preventblindness.org/acanthamoeba-keratitis-contact-lenses/
If you wear contact lenses, ask yourself these questions: […] If you answered yes to any of these questions, you could be at risk of getting a serious eye infection that could affect your vision, cause significant vision loss, or blindness. […] Individuals who wear any type of contact lenses are at the highest risk for contracting this infection. The two biggest risk factors are: […] The best way to prevent eye infections from AK is to always follow proper contact lens care guidelines as prescribed by your eye doctor. The following are key tips for contact lens care: […] Remove contact lenses before any activities with water, such as showering, bathing, swimming, or hot tub use. […] Contact lenses should never be rinsed with or stored in water (both tap or sterile water). […] Using daily disposable contact lenses and throwing them away each day is often the safest way to avoid infection.
- #29 New solutions in the prevention and treatment of Acanthamoeba keratitis | Eye Newshttps://www.eyenews.uk.com/features/ophthalmology/post/new-solutions-in-the-prevention-and-treatment-of-acanthamoeba-keratitis
Existing contact lens solutions are highly effective in the elimination of bacterial and fungal pathogens, but less so, Acanthamoeba. […] The use of hydrogen peroxide containing contact lens solutions is commonplace. […] As such, a solution that fails to act upon cysts as well as trophozoites cannot fully prevent infection. […] The two-step solutions, however, are effective against both stages and would be the preferred solution for combatting the parasite. […] It is a recurring theme then, that while we have several compounds that can kill the trophozoite stage, we lack an effective compound that can kill cysts without causing damage to the eye itself. […] There is a growing need for an effective preventive strategy to eliminate the risk of Acanthamoeba contaminating contact lenses and infecting the eye.
- #30 Acanthamoeba Keratitis: Symptoms, Treatment & Preventionhttps://my.clevelandclinic.org/health/diseases/21560-acanthamoeba-keratitis
Avoid getting water directly in your eyes. If your eyes feel dry, use artificial tear drops that are intended for use in the eye. If you need to rinse your eyes, contact lens solution is safer than using tap water. […] Take precautions if youre at higher risk for AK infection. If you have immune system issues or an eye injury that makes you vulnerable to an infection, dont take chances. Avoid swimming or showering in ways that could allow AK in water (even treated water) to get into your eyes. […] Use eye protection to avoid injuries. AK infections are always a threat with eye injuries. Protecting your eyes keeps them safe from damage, which also keeps microbes out.
- #31 Acanthamoeba Keratitis & Contact Lenses – Prevent Blindness Iowahttps://iowa.preventblindness.org/acanthamoeba-keratitis-contact-lenses/
Contact lens cases should always be cleaned with fresh solution not water. […] Consider keeping your contact lenses outside the bathroom, to reduce the risk of water contamination. […] We encourage people not to swim with contact lenses in at all due to the risk of Acanthamoeba keratitis. […] Diligence and early detection will increase the chances of successful treatment and prevent vision loss. […] Acanthamoeba keratitis is treated with both eye drops and oral medications. […] If your infection does not improve with the above treatments, you may need to undergo a corneal transplant, where all or part of the cornea is removed and then replaced with healthy donor tissue. […] Even if treated, AK may be in the hibernating stage and resist treatment.
- #32 Tips: How to Avoid Acanthamoeba Keratitishttps://www.eyecareplus.com.au/tips-how-to-avoid-acanthamoeba-keratitis/
The best way to deal with acanthamoeba keratitis is to never get it in the first place. For the most part, acanthamoeba keratitis prevention comes down to keeping your contact lens hygiene standards high. […] Here are a few things to remember: Never, ever rinse your lenses or cases with tap water. […] If you have extended-wear contact lenses, clean, rub and rinse your lenses each time you remove them. Rubbing and rinsing them helps to remove microbes and residue. […] Dont wear your contacts in the shower, in the pool, in lakes or rivers or in a hot tub. […] When handling your contact lenses, wash your hands with soap and water. Make sure you thoroughly dry your hands before handling your lenses. […] Change your contact lens case every three months. […] Put fresh contact lens solution in your case every day. […] Never reuse or top-off old solution in your contacts case. […] If you scratch your cornea (front of the eye), avoid contact lenses for a few days until your eye heals. […] Dont sleep with your contacts in.
- #33 New solutions in the prevention and treatment of Acanthamoeba keratitis | Eye Newshttps://www.eyenews.uk.com/features/ophthalmology/post/new-solutions-in-the-prevention-and-treatment-of-acanthamoeba-keratitis
To date, compounds such as these are limited. Recently though, our team has been successful in the identification of a series of compounds that are effective against both Acanthamoeba trophozoites and cysts and remain hopeful that they may offer a new method of combatting the global rise of these parasites. […] The recent explosion in AK cases has highlighted how drastically underprepared we are to deal with the problem. […] Our breakthrough in the finding of a series of effective anti-Acanthamoeba compounds is fortified by not only the multiplicity of the compounds and their ability to work in combination with other compounds, but in the additional work that has been compiled into potential resistance mechanisms and in the mechanism of action of these effective compounds specifically with the prevention of Acanthamoeba keratitis in mind.
- #34 Community Eye Health Journal » Microbial keratitis: a community eye health approachhttps://archive.cehjournal.org/article/microbial-keratitis-a-community-eye-health-approach-article/
Microbial keratitis is an infection of the cornea. […] Given the limitations associated with available treatment options, secondary prevention (i.e. the prevention of visual impairment in someone with a corneal injury and/or infection) may be the best option for reducing vision loss associated with microbial keratitis. […] A series of studies in South-east Asia suggested that antimicrobial ointment applied soon after a corneal abrasion could dramatically reduce the incidence of microbial keratitis. […] These studies demonstrated that village health workers can be trained to diagnose corneal abrasions and provide prophylactic treatment, and suggested that this simple intervention might be effective. […] Prophylaxis. Once a corneal abrasion is identified, antibiotic and antifungal ointments should be applied three times a day for 3 days to prevent infection. […] In low- and middle-income countries, the prevention of microbial keratitis is a promising intervention for reducing corneal blindness.
- #35 Bacterial Keratitis Treatment & Management: Medical Care, Surgical Care, Consultationshttps://emedicine.medscape.com/article/1194028-treatment
Topical antibiotics are given routinely after traumatic injury to the cornea (including surgery). […] Preventing contamination of topical medications and the use of sterile contact lens solutions are critical steps in preventing contact lens-related infections.
- #36 CRSToday | Preventing Post-LASIK Keratitishttps://crstoday.com/articles/2007-jan/crst0107_12-php
Preventing Post-LASIK Keratitis […] For prophylaxis against post-LASIK infectious keratitis, surgeons need to implement several steps. Preoperatively, all patients considering refractive surgery should have a thorough examination of their eyelids and lacrimal apparatus. Treating infectious lid disease prior to LASIK with hot compresses and a topical antibiotic ointment applied three times daily to the lid margin may decrease the risk of a bacterial keratitis. […] A 10 betadine solution applied to the eyelids prior to cataract surgery has been shown to decrease the incidence of endophthalmitis postoperatively, and this technique is recommended by many clinicians for LASIK. Proper methods of sterilization can prevent the use of contaminated instruments. Because several epidemics of atypical mycobacteria have been associated with the use of nonsterile water to clean instruments or the use of ice during LASIK surgery, all fluids applied to the eye before, during, and after LASIK should be disinfected.
- #37 CRSToday | Preventing Post-LASIK Keratitishttps://crstoday.com/articles/2007-jan/crst0107_12-php
Antibiotic prophylaxis for LASIK should provide a broad-based spectrum of coverage with an emphasis on gram-positive organisms. Ophthalmologists should choose a nontoxic antibiotic to promote epithelial healing and provide coverage against atypical mycobacteria. Finally, the appropriate antibiotic will penetrate effectively into the cornea and achieve therapeutic levels in the middle stroma. Fourth-generation fluoroquinolones (gatifloxacin 0.3 and moxifloxacin 0.5) for the antibiotic prophylaxis against infection following LASIK and PRK are recommended, because they are best suited to meet the aforementioned criteria.
- #38 Herpes Simplex Virus (HSV) Keratitis Treatment & Management: Approach Considerations, Infectious Epithelial Keratitis, Stromal Keratitishttps://emedicine.medscape.com/article/1194268-treatment
Active HSV keratitis is an absolute contraindication to laser corneal refractive surgery (ie, LASIK, PRK) or other corneal procedures (collagen cross-linking). Inactive keratitis or a history of previous HSV disease also is considered a relative contraindication. Recurrence of HSV keratitis after refractive surgery is a well-known complication. However, case reports have documented good refractive surgery outcomes in selected patients whose keratitis has been inactive for at least 1 year and in whom perioperative systemic antiviral prophylaxis is used. […] Ongoing research into HSV vaccination is being conducted. While nearly all developmental vaccines are targeting HSV-2 and genital herpes, evidence suggests that these vaccines may offer cross-protection in preventing ocular HSV-1 infections. However, concerns remain that a boost in immune response to HSV after vaccination may exacerbate herpetic stromal keratitis.
- #39 Prevention and Treatment of Cytarabine-Induced Keratoconjunctivitishttps://jhoponline.com/issue-archive/2015-issues/march-vol-5-no-1/16337:prevention-and-treatment-of-cytarabine-induced-keratoconjunctivitis
Corneal toxicity with high-dose cytarabine is a well-established risk of therapy. Routine prophylaxis with eye drops, usually topical corticosteroid drops, is an established part of high-dose cytarabine treatment protocols. Without topical corticosteroid prophylaxis, incidences of keratoconjunctivitis have been reported in 85% to 100% of cases; the occurrence of clinically significant symptoms with the use of prophylaxis is reported in 8% to 16% of cases. […] Prophylaxis is generally not recommended at doses 1000 mg/m2. Suggested prophylaxis is corticosteroid eye drops; however, other agents and combinations have been used successfully. These include a variety of preparations, including tear replacement solutions and topical, nonsteroidal anti-inflammatory drops. Every 4- or 6-hour administration on a strict schedule appears to provide the most benefit, and drops should be continued at least 48 hours after the last cytarabine dose. The mechanism of conjunctivitis prevention is unclear, but may rely on a decreased replication rate induced by corticosteroids impacting DNA replication in corneal cells. An additional mechanism of action may be a diluting effect on the cytarabine concentration; 1 trial showed benefits achieved from frequent use of artificial tears. […] Unless a deoxycytidine product is developed and proven successful, the information currently available would support the addition of an NSAID eye drop to corticosteroids for high-risk or symptomatic patients. Additional research is clearly warranted in this area.
- #40https://link.springer.com/article/10.1007/s12630-022-02380-4
Potentially vision-threatening ocular surface disorders have been found in over 50% of intensive care unit (ICU) patients. […] Appropriate eye care protocols in the ICU can prevent or reduce the severity of ocular complications. […] In summary, ocular protection varies across ICUs, with some having no protocols in place for ocular protection. […] These findings suggest that suboptimal eye care to prevent exposure keratitis is provided in Ontario ICUs and that evidence-based protocols should be developed and implemented.
- #41 Exposure keratopathy – Wikipediahttps://en.wikipedia.org/wiki/Exposure_keratopathy
If increased corneal exposure is detected, several preventive measures can be done to prevent keratitis. Artificial eye drops and eye ointments may be used to keep the eyes moist. Since frequent use of eye drops with preservatives can promote inflammation, it is better to choose preservative free artificial tear drops and lubricating eye drops. Bandage silicone hydrogel or scleral contact lens may be used to protect cornea. But, risk of infection is more with bandage contact lens use. Moisture goggles may also be used to protect cornea. Temporary or permanent tarsorrhaphy may be indicated to treat lagophthalmos. Gold weights can be inserted into the upper eyelid to treat facial nerve palsy.
- #42 Photokeratitis: Causes, Symptoms, Treatment and Preventionhttps://www.allaboutvision.com/conditions/keratitis/photokeratitis/
Wearing proper eye protection and safeguarding the eyes against the sun and UV radiation is key to preventing photokeratitis. […] Sunglasses and snow goggles that block or absorb at least 99% of ultraviolet rays should be worn when the eyes are exposed to sun or snow. Eyewear designed to wrap around the sides of the head or those with side shields are ideal when spending time outdoors. Wearing a hat with a visor or wide brim can help further protect the eyes from UV radiation. […] Wearing a welders helmet helps protect the eyes from UV radiation produced during arc welding. Full-face shield helmets with adjustable-shade levels are needed for sufficient protection. […] UV-absorbing contact lenses are available for individuals who spend considerable time outdoors or in environments affected by ultraviolet light.
- #43 The future of microbial keratitis treatment is brighthttps://europe.ophthalmologytimes.com/view/the-future-of-microbial-keratitis-treatment-ultraviolet-light-therapy-ocular-surface-eyelid-care
Ultraviolet lights potential in ocular care extends beyond structural reinforcement to antimicrobial applications, especially for microbial keratitis. […] Given these challenges, non-pharmacologic strategies such as UV light have gained attention for their antimicrobial properties, with UVC emerging as a promising optiona novel, non-invasive and resistance-independent treatment. […] Given its broad antimicrobial spectrum and resistance-independent mechanism, UV therapy has gained interest in ophthalmology as a potential treatment for infectious diseases like MK. A recent comprehensive review of UV treatments for superficial skin and ocular infections concluded that UVC therapy is a promising adjunct or alternative to conventional antibiotics. […] UVC therapy has the potential to become a gold standard treatment for MK, improving patient outcomes and reducing the global burden of corneal blindness. Future research should focus on piloting the in vivo use of UVC in patients to assess its safety and efficacy, optimising dosing protocols and eventually undertaking large-scale clinical trials.
- #44 Can artificial tears prevent Acanthamoeba keratitis? An in vitro approach | Parasites & Vectors | Full Texthttps://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-018-2639-5
The present study uses, for the first time, CTC stain analyzed by flow cytometry to establish Acanthamoeba viability demonstrating its usefulness and complementarity with the traditional stain, Trypan Blue. […] Artelac Splash, with no preservatives, and Optava Fusion, with Purite, have not shown any amoebicidal activity. […] On the contrary, promising results presented by Ocultect, with BAK, open up a new possibility for Acanthamoeba keratitis prophylaxis and treatment although in vivo studies should be carried out. […] In view of these results, we must highlight the importance of the data obtained with both methods used to investigate the viability of Acanthamoeba trophozoites. […] Finally, in this study, only Oculotect was demonstrated to have an important and durable amoebicidal effect on Acanthamoeba trophozoites. […] This characteristic means that it is not advisable to use this artificial tear concomitantly with soft lenses. […] Nevertheless, studies in corneal models or even in patients are needed to establish the in vivo amoebicidal effect of this kind of artificial tear formulation.
- #45 How to Treat Keratitis: Effective Care and Prevention Tipshttps://nextcare.com/health-resources/treat-keratitis-care-and-prevention/
If not caught early or not taken seriously, neglecting how to treat keratitis properly can snowball into major eye troubles. Hereâs why dealing with it swiftly is essential: […] Knowing how to treat keratitis requires early attention to those signs. Get immediate medical attention for persistent pain, redness, blurred vision, or unusual discharge to prevent more serious eye complications and vision loss.
- #46 Infectious Keratitis: Causes, Treatment, and Prevention Guidehttps://ophthalmologybreakingnews.com/infectious-keratitis-causes-treatment-prevention-guide
Preventing infectious keratitis involves adopting good eye hygiene practices. This includes proper contact lens care, regular eye examinations, and avoiding behaviors that may increase the risk of eye infections. […] Additionally, protecting the eyes from trauma, using protective eyewear in high-risk situations, and maintaining overall health contribute to reducing the likelihood of infectious keratitis. […] Prioritizing good eye hygiene, adopting protective measures, and making informed lifestyle choices contribute to a reduced risk of infectious keratitis and promote long-term eye wellness.