Choroba serca wrodzona
Zapobieganie i profilaktyka

Choroba serca wrodzona (CHD) występuje u około 1 na 110 noworodków i stanowi główną przyczynę śmiertelności wśród wad wrodzonych. Profilaktyka obejmuje suplementację kwasem foliowym (400 µg/dziennie w I trymestrze), kontrolę chorób przewlekłych (np. cukrzycy, fenyloketonurii, tocznia), unikanie alkoholu, tytoniu i toksyn, szczepienia przeciw różyczce oraz ostrożność w stosowaniu leków. Wczesna diagnostyka prenatalna i badania przesiewowe noworodków, w tym pulsoksymetria, są kluczowe dla wykrycia wad serca. Profilaktyka infekcyjnego zapalenia wsierdzia (IE) jest zalecana u pacjentów z wysokim ryzykiem, m.in. z nienaprawioną siniczą wadą serca lub po zabiegach z użyciem materiałów protetycznych, z zastosowaniem amoksycyliny (50 mg/kg, max 2 g) przed inwazyjnymi procedurami stomatologicznymi. Dodatkowo, higiena jamy ustnej, pielęgnacja skóry i szybkie leczenie infekcji są istotne w zapobieganiu IE.

Choroba serca wrodzona – Profilaktyka i Zapobieganie

Choroba serca wrodzona (CHD) to najczęstsza wada wrodzona, występująca u około 1 na 110 urodzeń. Jest to główna przyczyna śmiertelności noworodków spośród wszystkich wad wrodzonych. Chociaż w wielu przypadkach nie można całkowicie zapobiec wrodzonym wadom serca, istnieją działania profilaktyczne, które mogą zmniejszyć ryzyko ich wystąpienia oraz zapobiec powikłaniom u osób już zdiagnozowanych.12

Profilaktyka prenatalna

Ponieważ stosunkowo niewiele wiadomo o dokładnych przyczynach chorób serca wrodzonych, nie ma gwarantowanego sposobu na ich uniknięcie. Jednak istnieją czynniki, które mogą zmniejszyć ryzyko ich wystąpienia:34

  • Suplementacja kwasem foliowym – Przyjmowanie 400 mikrogramów kwasu foliowego dziennie, zwłaszcza w pierwszym trymestrze ciąży (pierwsze 12 tygodni), obniża ryzyko urodzenia dziecka z wrodzoną wadą serca, jak również innymi wadami wrodzonymi567
  • Kontrola chorób przewlekłych – Kobiety z cukrzycą powinny utrzymywać prawidłowy poziom cukru we krwi przed zajściem w ciążę i podczas niej. Podobnie osoby z fenyloketonurią (PKU) czy toczniem powinny mieć dobrze kontrolowane schorzenia przed ciążą89
  • Unikanie szkodliwych substancji – Należy unikać alkoholu, tytoniu i narkotyków podczas ciąży, a także ekspozycji na dym tytoniowy i silne środki chemiczne1011
  • Szczepienia – Szczepienie przeciwko różyczce przed ciążą jest istotne, ponieważ infekcja różyczką w czasie ciąży może prowadzić do wad serca u płodu1213
  • Ostrożność w stosowaniu leków – Należy skonsultować z lekarzem wszystkie przyjmowane leki, zarówno na receptę, jak i bez recepty, przed zajściem w ciążę i podczas niej1415
  • Regularne badania prenatalne – Umożliwiają wczesne wykrycie potencjalnych problemów sercowych u płodu16

Badania genetyczne i poradnictwo

Badania genetyczne mogą odgrywać ważną rolę w przypadku rodzin z historią chorób serca wrodzonych:17

  • Poradnictwo genetyczne – Rodziny, w których występują wrodzone wady serca, powinny rozważyć konsultacje z doradcą genetycznym, szczególnie jeśli planują kolejne dziecko18
  • Badania przesiewowe – Testy genetyczne mogą pomóc w identyfikacji potencjalnego ryzyka u kolejnych dzieci19
  • Ryzyko nawrotu – Ryzyko wystąpienia wrodzonej wady serca jest trzykrotnie wyższe, jeśli matka, ojciec lub rodzeństwo dziecka ma CHD2021

Badania przesiewowe noworodków

Wczesna diagnostyka jest kluczowa dla skutecznego leczenia wrodzonych wad serca:22

  • Obowiązkowe badania przesiewowe – W większości miejsc na świecie (w tym w Stanach Zjednoczonych) obowiązują badania przesiewowe wszystkich noworodków w kierunku wrodzonych wad serca przed wypisem ze szpitala2324
  • Pulsoksymetria – Jest to bezpieczna, nieinwazyjna metoda, która umożliwia wykrycie krytycznych wrodzonych wad serca u noworodków, zapobiegając niewydolności układu krążenia i śmierci25
  • Diagnostyka prenatalna – W przypadku ciąż wysokiego ryzyka zalecane są szczegółowe badania prenatalne, w tym echokardiografia płodowa26

Profilaktyka infekcyjnego zapalenia wsierdzia

Osoby z wrodzonymi wadami serca są narażone na zwiększone ryzyko infekcyjnego zapalenia wsierdzia (IE), które może mieć poważny wpływ na rokowanie, z 10-15% śmiertelnością. Dlatego właściwa profilaktyka jest kluczowa.27

Profilaktyka antybiotykowa

Zgodnie z aktualnymi wytycznymi, profilaktyka antybiotykowa zalecana jest tylko dla określonych grup wysokiego ryzyka:2829

  • Grupy wysokiego ryzyka – Obejmują pacjentów z:
    • Nienaprawioną siniczą wrodzoną wadą serca (w tym z zespoleniami paliatywnymi i konduitami)3031
    • Całkowicie naprawioną wadą serca z materiałem protetycznym lub urządzeniem (np. urządzenie do zamknięcia przegrody), w ciągu pierwszych sześciu miesięcy po zabiegu3233
    • Naprawioną wadą serca z pozostałym ubytkiem w miejscu lub sąsiadującym z miejscem protezy lub urządzenia protetycznego34
  • Zabiegi wymagające profilaktyki – Głównie inwazyjne zabiegi stomatologiczne i procedury w obrębie jamy ustnej35
  • Antybiotyki rekomendowane – Najczęściej stosowana jest amoksycylina (50 mg/kg, maksymalnie 2 g) podawana doustnie 30-60 minut przed zabiegiem. Istnieją alternatywy dla osób uczulonych na penicylinę36

Inne metody profilaktyki infekcyjnego zapalenia wsierdzia

Oprócz profilaktyki antybiotykowej, istnieją inne ważne metody zapobiegania IE:37

  • Higiena jamy ustnej – Utrzymanie dobrej higieny jamy ustnej, regularne szczotkowanie zębów i wizyty u dentysty są kluczowe dla osób z grupy ryzyka3839
  • Pielęgnacja skóry – Właściwa higiena skóry i unikanie piercing’u oraz tatuaży (zalecane przez wytyczne ESC z 2023 roku)40
  • Szybkie leczenie infekcji – Terminowe leczenie zakażeń patogenami, które mogą powodować zapalenie wsierdzia41
  • Zamknięcie przetrwałego przewodu tętniczego (PDA) lub ubytku przegrody międzykomorowej (VSD) – W przypadku pacjentów z historią zapalenia wsierdzia zamknięcie tych ubytków może zmniejszyć ryzyko dalszych epizodów IE42
  • Edukacja pacjentów – Lekarze opiekujący się osobami z CHD powinni regularnie informować ich o potencjalnym ryzyku IE, jego objawach klinicznych i znaczeniu wczesnej diagnozy43

Profilaktyka zakażeń RSV u dzieci z CHD

Zakażenie wirusem syncytialnym (RSV) może mieć ciężki przebieg u dzieci z wrodzonymi wadami serca, zwiększając ryzyko chorobowości i śmiertelności, wymagając hospitalizacji i intensywnej opieki.44

paliwizumabem”>Profilaktyka paliwizumabem

Paliwizumab to przeciwciało monoklonalne stosowane w profilaktyce zakażeń RSV u dzieci z wysokim ryzykiem:45

  • Wskazania – W Włoszech, zgodnie z zaleceniami organów regulacyjnych i towarzystw naukowych, profilaktyka paliwizumabem zalecana jest u dzieci poniżej 2 roku życia z hemodynamicznie istotnymi CHD (HS-CHD), z zastoinową niewydolnością serca wymagającą leczenia, sinicą z saturacją systemową poniżej 90% lub nadciśnieniem płucnym, a także u dzieci po przeszczepie serca46
  • Skuteczność – Badania potwierdzają ochronne działanie paliwizumabu u pacjentów z HS-CHD, zmniejszając wskaźnik hospitalizacji, chorobowość i śmiertelność w tej grupie pacjentów47
  • Korzyści – Pasywna immunoprofilaktyka paliwizumabem może wpływać na dostępność i wykorzystanie zasobów opieki zdrowotnej48
  • Aktualizacja wytycznych – Przed 2014 rokiem dzieci w wieku 0-24 miesięcy z wrodzoną wadą serca kwalifikowały się do otrzymania profilaktyki RSV. Zaktualizowane wytyczne opublikowane w 2014 roku ograniczyły zalecenie podawania paliwizumabu tylko dzieciom z wrodzoną wadą serca poniżej 12 miesiąca życia49

Profilaktyka u dorosłych z wrodzonymi wadami serca

Dzięki postępom w leczeniu chirurgicznym i opiece medycznej, coraz więcej osób z wrodzonymi wadami serca dożywa dorosłości. Ta populacja wymaga specjalistycznej opieki i działań prewencyjnych.50

Kontrola czynników ryzyka chorób sercowo-naczyniowych

Dorośli z CHD powinni podejmować działania mające na celu zmniejszenie ryzyka rozwoju dalszych problemów sercowo-naczyniowych:51

  • Regularna aktywność fizyczna – Ćwiczenia fizyczne pod nadzorem lekarza lub specjalisty rehabilitacji kardiologicznej52
  • Zdrowa dieta – Przestrzeganie diety zdrowej dla serca, takiej jak dieta śródziemnomorska lub DASH53
  • Kontrola masy ciała – Utrzymywanie umiarkowanej, zdrowej masy ciała54
  • Zarządzanie parametrami zdrowotnymi – Kontrola ciśnienia krwi, cholesterolu i poziomu cukru we krwi55
  • Zaprzestanie palenia – Osoby palące powinny rzucić palenie56

Terapia statynami w profilaktyce pierwotnej

Statyny są ważnym elementem profilaktyki pierwszorzędowej chorób sercowo-naczyniowych, ale są niedostatecznie wykorzystywane u dorosłych z CHD:57

  • Niedostateczne przepisywanie – Badania pokazują, że dorośli z wrodzoną wadą serca rzadziej otrzymują statyny w ramach profilaktyki pierwotnej w porównaniu z osobami bez tej choroby, mimo podobnych wyników oceny ryzyka miażdżycowej choroby sercowo-naczyniowej (ASCVD)5859
  • Wpływ na zdrowie – Z uwagi na dłuższe życie populacji z wrodzonymi wadami serca, ASCVD ma coraz większy wpływ na ich ogólny stan zdrowia60
  • Potrzeba aktywnego nadzoru – Lekarze podstawowej opieki zdrowotnej, kardiolodzy i specjaliści ASCVD powinni aktywnie monitorować czynniki ryzyka ASCVD i priorytetowo traktować profilaktykę opartą na wytycznych w tej populacji61

Specjalistyczna opieka dla dorosłych z CHD

Regularna specjalistyczna opieka jest kluczowa dla dorosłych z wrodzonymi wadami serca:62

  • Akredytowane centra ACHD – Poszukiwanie rutynowej opieki w specjalistycznych ośrodkach kardiologicznych akredytowanych przez organizacje takie jak Adult Congenital Heart Association może pomóc w prowadzeniu dłuższego i zdrowszego życia63
  • Wczesna interwencja – Regularne wizyty kontrolne umożliwiają wczesne wykrycie i korekcję problemów lub ich całkowite zapobieżenie64
  • Kompleksowa opieka – Specjalistyczne ośrodki oferują kompleksową opiekę, od poradnictwa w zakresie zapobiegania chorobom (jak zdrowsze odżywianie, ćwiczenia czy rzucenie palenia) po zaawansowaną opiekę medyczną i chirurgiczną65
  • Opieka położnicza – Kobiety w ciąży lub rozważające ciążę powinny korzystać ze specjalistycznej opieki zespołów kardio-położniczych, które zapewniają specjalistyczną opiekę prenatalną i prekoncepcyjną dla kobiet z chorobami serca66

Badania i innowacje w zapobieganiu CHD

Postęp w badaniach nad wrodzonymi wadami serca może prowadzić do lepszych metod zapobiegania i leczenia tych schorzeń:67

  • Współpraca badawcza – Organizacje takie jak The Children’s Heart Foundation i Cardiac Networks United współpracują, aby przyspieszyć badania nad diagnozowaniem, leczeniem i zapobieganiem wrodzonym wadom serca68
  • Dostęp do danych – Takie partnerstwa umożliwiają badaczom dostęp do danych potrzebnych do realizacji najbardziej obiecujących i wpływowych badań69
  • Badania nad całym cyklem życia – Poprawa wyników leczenia pacjentów z wrodzoną wadą serca wymaga badań naukowych skoncentrowanych nie tylko na efektach krótkoterminowych, ale na kluczowych wynikach w całym cyklu życia70
  • Translacja wyników badań do praktyki klinicznej – Kluczowe są wysiłki mające na celu przełożenie nowej wiedzy na konkretne udoskonalenia w opiece nad pacjentami71

Profilaktyka wrodzonych wad serca obejmuje szeroki zakres działań – od odpowiedzialnej opieki przedporodowej, przez badania przesiewowe noworodków, po całożyciową specjalistyczną opiekę nad dorosłymi z CHD. Chociaż nie wszystkim wrodzonym wadom serca można zapobiec, powyższe strategie mogą znacząco zmniejszyć ryzyko ich wystąpienia lub pomóc w zarządzaniu istniejącymi schorzeniami, poprawiając jakość i długość życia osób dotkniętych tymi chorobami.

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  1. 09.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Congenital Heart Defects
    https://www.health.ny.gov/diseases/birth_defects/chd.htm
    Congenital Heart Defects (CHDs) are the most common birth defects, occurring in about 1 in 110 births. […] This webpage provides information about CHDs, prevention steps for prospective parents and resources for specialized care. […] CHDs are the most common birth defects that cause infant death. While most causes of CHDs are unknown, there may be prevention activities that prospective mothers (and fathers) can do to help increase the chance of having a baby with a healthy heart: […] Get Healthy Before You Are Pregnant […] Get Prenatal Care […] Get Enough Folic Acid. […] A babys risk of having a CHD is increased by 3 times if the mother, father, or sibling has a CHD. People with CHDs should speak to their health care providers about preconception counseling to find out if they are able to have a safe or low-risk pregnancy.
  • #2 New York State Department of Health Recognizes Congenital Heart Defect Week
    https://www.health.ny.gov/press/releases/2025/2025-02-13_chd_week.htm
    Congenital Heart Defects (CHDs) are the most common birth defects, occurring in about 1 in 110 births. […] CHDs are the most common birth defects that cause infant death. While most causes of CHDs are unknown, there may be prevention activities that prospective parents can do to help increase the chance of having a baby with a healthy heart: […] Get Healthy Before You Are Pregnant […] Get Prenatal Care […] Get Enough Folic Acid. […] A baby’s risk of having a CHD is 3 times higher if their mother, father, or sibling has a CHD. People with CHDs should speak to their health care providers about preconception counseling to find out how to have the safest possible pregnancy.
  • #3
    https://www.nhs.uk/conditions/congenital-heart-disease/prevention/
    As so little is known about the causes of congenital heart disease, there’s no guaranteed way of avoiding having a baby with the condition. […] However, if you’re pregnant, the following advice can help reduce the risk: […] Take 400 micrograms of folic acid supplement a day during the first trimester (first 12 weeks) of your pregnancy this lowers your risk of giving birth to a child with congenital heart disease, as well as several other types of birth defect. […] Avoid contact with people who are known to have an infection. […] If you have diabetes, make sure it’s controlled.
  • #4
    https://zana.com/a/congenital-heart-disease-prevention.1246
    As so little is known about the causes of congenital heart disease, there’s no guaranteed way of avoiding having a baby with the condition. […] However, if you’re pregnant, the following advice can help reduce the risk: Ensure you are vaccinated against rubella and flu. […] Take 400 micrograms of folic acid supplement a day during the first trimester (first 12 weeks) of your pregnancy this lowers your risk of giving birth to a child with congenital heart disease, as well as several other types of birth defect. […] If you have congenital heart disease and become pregnant, your congenital heart specialist will usually arrange an Echocardiogram (heart scan) for your baby approximately 20 weeks into your pregnancy. This is to check whether your baby has any evidence of congenital heart disease.
  • #5
    https://www.nhs.uk/conditions/congenital-heart-disease/prevention/
    As so little is known about the causes of congenital heart disease, there’s no guaranteed way of avoiding having a baby with the condition. […] However, if you’re pregnant, the following advice can help reduce the risk: […] Take 400 micrograms of folic acid supplement a day during the first trimester (first 12 weeks) of your pregnancy this lowers your risk of giving birth to a child with congenital heart disease, as well as several other types of birth defect. […] Avoid contact with people who are known to have an infection. […] If you have diabetes, make sure it’s controlled.
  • #6 Congenital heart defects in children – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/congenital-heart-defects-children/symptoms-causes/syc-20350074
    Because the exact cause of most congenital heart defects is unknown, it may not be possible to prevent these conditions. If you have a high risk of giving birth to a child with a congenital heart defect, genetic testing and screening may be done during pregnancy. […] There are some steps you can take to help reduce your child’s overall risk of heart problems present at birth such as: […] Get proper prenatal care. Regular checkups with a healthcare professional during pregnancy can help keep mom and baby healthy. […] Take a multivitamin with folic acid. Taking 400 micrograms of folic acid daily has been shown to prevent harmful changes in the baby’s brain and spinal cord. It also may help reduce the risk of congenital heart defects as well. […] Don’t drink or smoke. These lifestyle habits can harm a baby’s health. Also avoid secondhand smoke.
  • #7 Reducing the risk for congenital heart defects | March of Dimes
    https://www.marchofdimes.org/find-support/blog/reducing-risk-congenital-heart-defects
    People who smoke anytime during the month before their pregnancy or during the first 3 months of pregnancy are more likely to have a baby with a CHD than those who don’t smoke. […] Using drugs such as opioids during pregnancy has been linked to an increased risk of birth defects, including CHDs. […] Here are some things you can do to reduce the risk of CHDs and increase your chances of having a healthy pregnancy and a healthy baby. […] Folic acid may help prevent heart defects. Take a vitamin supplement with 400 micrograms of folic acid in it every day, even if you’re not trying to get pregnant. […] Don’t smoke, drink alcohol or take drugs during pregnancy. Talk to your health care provider if you need help to quit. […] Get caught up on vaccinations before you get pregnant. Your provider can check to see if you are immune from rubella.
  • #8 Congenital Heart Defects – Screening and Prevention | NHLBI, NIH
    https://www.nhlbi.nih.gov/health/congenital-heart-defects/screening
    Almost all newborns in the United States are screened for congenital heart defects shortly after birth. However, if you are at high risk for having a baby with a congenital heart defect, your doctor may recommend screening before the baby is born or strategies to help prevent a congenital heart defect. […] While you cannot always prevent a congenital heart defect, you can take steps to lower your baby’s risk. […] Avoid certain medicines if you are trying to get pregnant or are pregnant. Talk to your doctor about what medicines you take and ask which are safe to take during pregnancy. […] Control existing medical conditions, such as diabetes and phenylketonuria, which can raise your risk of having a baby with a congenital heart defect. […] Meet with a genetic counselor if you, your spouse, or one of your children have a congenital heart disease and you are planning to have another child. A genetic counselor can answer questions about the risks and explain the choices that are available. […] Quit smoking and avoid secondhand smoke.
  • #9 Reducing the risk for congenital heart defects | March of Dimes
    https://www.marchofdimes.org/find-support/blog/reducing-risk-congenital-heart-defects
    If you have diabetes, work with your provider to control your blood sugar before and during pregnancy. Get your diabetes under control 3 to 6 months before you start trying to get pregnant. […] If you have lupus, work with your provider to get your condition under control 6 months before you get pregnant. […] If you have PKU, work with your provider to get your condition under control at least 3 months before you get pregnant.
  • #10 Congenital Heart Disease: Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/21674-congenital-heart-disease
    Can congenital heart disease be prevented? There arent any proven strategies to prevent CHD. People are born with it, usually from unknown causes. Its beyond their control. […] Scientists dont have all the answers yet as to what causes congenital heart defects other than random gene mutations. But some things like smoking, alcohol and certain medications place you at a higher risk, and you should avoid these during pregnancy. […] You should follow your healthcare providers instructions during pregnancy, including: Dont use recreational drugs. Get all recommended screening tests during pregnancy to detect problems as early as possible. Manage any health conditions, such as diabetes and phenylketonuria. Stop smoking and avoid secondhand smoke. Avoid alcohol.
  • #11 Congenital heart defects in children – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/congenital-heart-defects-children/symptoms-causes/syc-20350074
    Get a rubella vaccine. Also called German measles, having rubella during pregnancy may affect a baby’s heart development. Get vaccinated before trying to get pregnant. […] Control blood sugar. If you have diabetes, good control of your blood sugar can reduce the risk of congenital heart defects. […] Manage chronic health conditions. If you have other health conditions, talk to your healthcare professional about the best way to treat and manage them. […] Avoid harmful substances. During pregnancy, have someone else do any painting and cleaning with strong-smelling products. […] Tell your care team about your medicines. Some medicines can cause congenital heart defects and other health conditions present at birth. Tell your care team about all the medicines you take, including those bought without a prescription.
  • #12 Congenital heart defects in children – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/congenital-heart-defects-children/symptoms-causes/syc-20350074
    Get a rubella vaccine. Also called German measles, having rubella during pregnancy may affect a baby’s heart development. Get vaccinated before trying to get pregnant. […] Control blood sugar. If you have diabetes, good control of your blood sugar can reduce the risk of congenital heart defects. […] Manage chronic health conditions. If you have other health conditions, talk to your healthcare professional about the best way to treat and manage them. […] Avoid harmful substances. During pregnancy, have someone else do any painting and cleaning with strong-smelling products. […] Tell your care team about your medicines. Some medicines can cause congenital heart defects and other health conditions present at birth. Tell your care team about all the medicines you take, including those bought without a prescription.
  • #13 Congenital Heart Disease: A-to-Z Guide from Diagnosis to Treatment to Prevention | DrGreene
    https://www.drgreene.com/articles/congenital-heart-disease
    Congenital heart disease is often impossible to prevent. Avoiding toxic exposures, such as drinking alcohol during pregnancy, prevents some CHD. Similarly, avoiding certain infections during pregnancy, such as rubella (preventable by immunization), can prevent some CHD.
  • #14 Congenital Heart Disease: Types, Symptoms, Causes, and TreatmentHealthline
    https://www.healthline.com/health/congenital-heart-disease
    How Can Congenital Heart Disease Be Prevented? […] Women who are pregnant or plan on becoming pregnant can take certain precautions to lower their risk of giving birth to a baby with a congenital heart defect: […] If you’re planning on becoming pregnant, talk to your doctor about any prescription or over-the-counter medications you’re taking. […] If you have diabetes, make sure your blood sugar levels are under control before becoming pregnant. It’s also important to work with your doctor to manage the disease while pregnant. […] If you weren’t vaccinated against rubella, or German measles, avoid exposure to the disease and speak with your doctor about prevention options. […] If you have a family history of congenital heart defects, ask your doctor about genetic screening. Certain genes may contribute to abnormal heart development. […] Avoid drinking alcohol and using illegal drugs during pregnancy.
  • #15 Reducing the risk for congenital heart defects | March of Dimes
    https://www.marchofdimes.org/find-support/blog/reducing-risk-congenital-heart-defects
    A teratogen is something that can cause a birth defect or increase the risk of a baby having a birth defects. Certain medicines are teratogens because they can increase the risk of birth defects if they are used during pregnancy. […] Congenital heart defects (also called CHDs) can happen in the first 6 weeks of pregnancy, sometimes before you even know you’re pregnant. […] Experts aren’t sure what causes most CHDs. But these substances can increase the risk of your baby having a CHD. […] If you are taking any of these medicines, make sure you talk to your provider before trying to get pregnant. […] No amount of alcohol is safe during pregnancy. Drinking alcohol during pregnancy can cause many problems, including increasing the risk of birth defects such as heart defects, hearing problems and vision problems.
  • #16 Congenital heart defects in children – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/congenital-heart-defects-children/symptoms-causes/syc-20350074
    Because the exact cause of most congenital heart defects is unknown, it may not be possible to prevent these conditions. If you have a high risk of giving birth to a child with a congenital heart defect, genetic testing and screening may be done during pregnancy. […] There are some steps you can take to help reduce your child’s overall risk of heart problems present at birth such as: […] Get proper prenatal care. Regular checkups with a healthcare professional during pregnancy can help keep mom and baby healthy. […] Take a multivitamin with folic acid. Taking 400 micrograms of folic acid daily has been shown to prevent harmful changes in the baby’s brain and spinal cord. It also may help reduce the risk of congenital heart defects as well. […] Don’t drink or smoke. These lifestyle habits can harm a baby’s health. Also avoid secondhand smoke.
  • #17 Prevention and Congenital Heart Disease
    https://escholarship.org/uc/item/5fp8t16p
    Recurrence risk of congenital heart disease (CHD) in families with an affected first-degree relative is increased as compared with the general population. […] Advances in genetic testing and evidence that preconceptual folic acid supplementation may decrease risk of CHD warrant preventative counseling for at-risk families. […] Our goal was to document patterns of preconceptual folic acid supplementation and recurrence risk counseling in at-risk families in order to identify opportunities for improved preventative care. […] At-risk mothers with lower education are less likely to take preconceptual folic acid supplementation or receive recurrence risk counseling. Health care providers should proactively provide this information to all at-risk patients and develop collaborations with genetic services.
  • #18 Congenital Heart Defects – Screening and Prevention | NHLBI, NIH
    https://www.nhlbi.nih.gov/health/congenital-heart-defects/screening
    Almost all newborns in the United States are screened for congenital heart defects shortly after birth. However, if you are at high risk for having a baby with a congenital heart defect, your doctor may recommend screening before the baby is born or strategies to help prevent a congenital heart defect. […] While you cannot always prevent a congenital heart defect, you can take steps to lower your baby’s risk. […] Avoid certain medicines if you are trying to get pregnant or are pregnant. Talk to your doctor about what medicines you take and ask which are safe to take during pregnancy. […] Control existing medical conditions, such as diabetes and phenylketonuria, which can raise your risk of having a baby with a congenital heart defect. […] Meet with a genetic counselor if you, your spouse, or one of your children have a congenital heart disease and you are planning to have another child. A genetic counselor can answer questions about the risks and explain the choices that are available. […] Quit smoking and avoid secondhand smoke.
  • #19 Nonsyndromic Congenital Heart Disease Panel Test – PreventionGenetics
    https://www.preventiongenetics.com/testInfo?val=Nonsyndromic-Congenital-Heart-Disease-Panel
    Patients with congenital heart defects are candidates for testing. […] Improved surgical and medical interventions has resulted in increasing prevalence of CHDs in adults. Determining the genetic etiology of CHDs allows for the identification of potential unanticipated extracardiac involvement, assess recurrence risk in future pregnancies, and can provide a more accurate prognosis. […] The exact sensitivity of this panel is not known; however, sensitivity in nonsyndromic CHD is lower than syndromic forms. For isolated CHDs exome sequencing studies have found pathogenic variants in 16-20% of cases compared to 30-39% in syndromic forms. […] This test is performed using Next-Gen sequencing with additional Sanger sequencing as necessary.
  • #20 Congenital Heart Defects
    https://www.health.ny.gov/diseases/birth_defects/chd.htm
    Congenital Heart Defects (CHDs) are the most common birth defects, occurring in about 1 in 110 births. […] This webpage provides information about CHDs, prevention steps for prospective parents and resources for specialized care. […] CHDs are the most common birth defects that cause infant death. While most causes of CHDs are unknown, there may be prevention activities that prospective mothers (and fathers) can do to help increase the chance of having a baby with a healthy heart: […] Get Healthy Before You Are Pregnant […] Get Prenatal Care […] Get Enough Folic Acid. […] A babys risk of having a CHD is increased by 3 times if the mother, father, or sibling has a CHD. People with CHDs should speak to their health care providers about preconception counseling to find out if they are able to have a safe or low-risk pregnancy.
  • #21 New York State Department of Health Recognizes Congenital Heart Defect Week
    https://www.health.ny.gov/press/releases/2025/2025-02-13_chd_week.htm
    Congenital Heart Defects (CHDs) are the most common birth defects, occurring in about 1 in 110 births. […] CHDs are the most common birth defects that cause infant death. While most causes of CHDs are unknown, there may be prevention activities that prospective parents can do to help increase the chance of having a baby with a healthy heart: […] Get Healthy Before You Are Pregnant […] Get Prenatal Care […] Get Enough Folic Acid. […] A baby’s risk of having a CHD is 3 times higher if their mother, father, or sibling has a CHD. People with CHDs should speak to their health care providers about preconception counseling to find out how to have the safest possible pregnancy.
  • #22 Congenital Heart Disease | Riley Children’s Health
    https://www.rileychildrens.org/health-info/congenital-heart-disease
    Congenital heart disease refers to health problems that come from having a congenital heart defect—a common birth defect that occurs at some time during the first eight weeks of fetal development. […] In many cases, congenital heart defects can be diagnosed before birth through a fetal ultrasound. […] The state of Indiana requires that all newborns receive screening for congenital heart disease before they are allowed to go home—even those without symptoms. […] Most heart defects will require surgical repair; some require multiple surgeries.
  • #23 Congenital Heart Defects – Screening and Prevention | NHLBI, NIH
    https://www.nhlbi.nih.gov/health/congenital-heart-defects/screening
    Almost all newborns in the United States are screened for congenital heart defects shortly after birth. However, if you are at high risk for having a baby with a congenital heart defect, your doctor may recommend screening before the baby is born or strategies to help prevent a congenital heart defect. […] While you cannot always prevent a congenital heart defect, you can take steps to lower your baby’s risk. […] Avoid certain medicines if you are trying to get pregnant or are pregnant. Talk to your doctor about what medicines you take and ask which are safe to take during pregnancy. […] Control existing medical conditions, such as diabetes and phenylketonuria, which can raise your risk of having a baby with a congenital heart defect. […] Meet with a genetic counselor if you, your spouse, or one of your children have a congenital heart disease and you are planning to have another child. A genetic counselor can answer questions about the risks and explain the choices that are available. […] Quit smoking and avoid secondhand smoke.
  • #24 Critical Congenital Heart Disease
    https://oklahoma.gov/health/services/children-family-health/screening-and-special-services/newborn-screening-program/cchd.html
    Critical congenital heart disease (CCHD) screening has been recommended nationally by the Secretary for Health and Human Services and pulse oximetry screening for CCHD is endorsed by the American Heart Association, American Academy of Pediatrics and American College of Cardiology. […] CCHD is often treatable, and with early detection and treatment babies affected can often lead longer, healthier lives.
  • #25 Prevention of delayed diagnosis in congenital heart disease | Cardiology in the Young | Cambridge Core
    https://www.cambridge.org/core/journals/cardiology-in-the-young/article/prevention-of-delayed-diagnosis-in-congenital-heart-disease/B376E74ED7A40D585D5CD99BFD8ACEE1
    High-risk pregnancies have increased over the past decades in Europe. A nationwide study of the Netherlands reported a prenatal detection rate of severe CHD in an unselected population of 59.7%. […] Detection rates depend on technical developments, availability of modern ultrasound equipment, education of the sonographer, practical scanning experience, and feedback on the cases. […] Several working groups around the world stated pulse oximetry screening as a promising additional method to detect CHD in a newborn to prevent cardiovascular collapse and death. […] Pulse oximetry screening is a safe and non-invasive method that is easy to perform and has proven to detect critical CHD in newborns. […] In summary, a combination of prenatal ultrasound, detailed physical examination at birth, and pulse oximetry screening is the ideal method to improve the detection rate of critical CHD in newborns and is therefore recommended by this Association of European Pediatric and Congenital Cardiology Working Group.
  • #26
    https://zana.com/a/congenital-heart-disease-prevention.1246
    As so little is known about the causes of congenital heart disease, there’s no guaranteed way of avoiding having a baby with the condition. […] However, if you’re pregnant, the following advice can help reduce the risk: Ensure you are vaccinated against rubella and flu. […] Take 400 micrograms of folic acid supplement a day during the first trimester (first 12 weeks) of your pregnancy this lowers your risk of giving birth to a child with congenital heart disease, as well as several other types of birth defect. […] If you have congenital heart disease and become pregnant, your congenital heart specialist will usually arrange an Echocardiogram (heart scan) for your baby approximately 20 weeks into your pregnancy. This is to check whether your baby has any evidence of congenital heart disease.
  • #27 [Infective endocarditis prophylaxis in congenital heart disease] – PubMed
    https://pubmed.ncbi.nlm.nih.gov/28576635/
    Infective endocarditis can negatively impact prognosis of congenital heart disease and has a 10-15% incidence of mortality. New guidelines recommend prophylaxis of infective endocarditis only for high-risk group (cyanotic congenital heart disease, valvular prosthesis, previous endocarditis) and for some specific invasive dental procedures. […] New guidelines are focused mainly on oral and cutaneous hygiene. Native shunts and valvular disease are no more targets for prophylaxis. More than half of the physicians do not follow the new guidelines. High-velocity shunts like ventricular septal defect should be included in the at-risk congenital disease for infective endocarditis where prophylaxis should be applied. The new guidelines for prophylaxis of infective endocarditis did not impact on the incidence of infective endocarditis.
  • #28 Prevention of endocarditis: Antibiotic prophylaxis and other measures – UpToDate
    https://www.uptodate.com/contents/prevention-of-endocarditis-antibiotic-prophylaxis-and-other-measures
    Prevention of endocarditis: Antibiotic prophylaxis and other measures […] Measures for prevention of infective endocarditis (IE) are discussed here, including the clinical approach and rationale for antibiotic prophylaxis prior to dental procedures. […] The indications for IE prophylaxis in 2021 American Heart Association (AHA) guidelines are narrower than indications outlined in prior (AHA) guidelines. The approach of the 2023 European Society of Cardiology (ESC) guidelines is similar to that of the AHA guidelines. These guidelines take into consideration both patient-based and procedure-based risk factors for IE. […] Measures for prevention of IE include: […] – Maintenance of oral hygiene. […] – Antibiotic prophylaxis prior to invasive dental or invasive oral procedures. […] – Timely treatment of infections with pathogens likely to cause endocarditis.
  • #29 [Infective endocarditis prophylaxis in congenital heart disease] – PubMed
    https://pubmed.ncbi.nlm.nih.gov/28576635/
    Infective endocarditis can negatively impact prognosis of congenital heart disease and has a 10-15% incidence of mortality. New guidelines recommend prophylaxis of infective endocarditis only for high-risk group (cyanotic congenital heart disease, valvular prosthesis, previous endocarditis) and for some specific invasive dental procedures. […] New guidelines are focused mainly on oral and cutaneous hygiene. Native shunts and valvular disease are no more targets for prophylaxis. More than half of the physicians do not follow the new guidelines. High-velocity shunts like ventricular septal defect should be included in the at-risk congenital disease for infective endocarditis where prophylaxis should be applied. The new guidelines for prophylaxis of infective endocarditis did not impact on the incidence of infective endocarditis.
  • #30 Prevention of endocarditis: Antibiotic prophylaxis and other measures – UpToDate
    https://www.uptodate.com/contents/prevention-of-endocarditis-antibiotic-prophylaxis-and-other-measures
    – Antibiotic prophylaxis prior to surgery reduces the risk of surgical site infection, as discussed separately, and has been postulated to reduce the risk of subsequent endocarditis. A key example of this approach is antibiotic prophylaxis prior to cardiac surgery. […] – Closure of a patent ductus arteriosus or ventricular septal defect. […] Antibiotic prophylaxis is warranted for patients with cardiac conditions that confer the highest risk of adverse outcome from IE prior to invasive dental or invasive oral procedures. […] Conditions associated with highest risk of adverse outcomes from IE include: […] – Certain types of congenital heart disease including: […] – Unrepaired cyanotic congenital heart disease (patients with palliative shunts and conduits are still considered unrepaired).
  • #31 Guidelines for Endocarditis Prevention – Canadian Congenital Heart Alliance
    https://cchaforlife.org/learn-about-chd/guidelines-endocarditis-prevention/
    Those living with Congenital Heart Disease may be concerned developing Endocarditis or if they have been told they no longer require antibiotic prophylaxis. […] Prophylaxis is reasonable for patients with the following conditions: […] Congenital heart disease (CHD) […] Unrepaired cyanotic CHD, including palliative shunts and conduits […] Completely repaired congenital heart defect with prosthetic material or device, whether placed by surgery or by catheter intervention, during the first six months after the procedure […] Repaired CHD with residual defects at the site or adjacent to the site of a prosthetic patch or prosthetic device (which inhibit endothelialization) […] It should be noted that with the exception of the conditions listed above, antibiotic prophylaxis is no longer recommended for any other form of CHD.
  • #32 Prevention of endocarditis: Antibiotic prophylaxis and other measures – UpToDate
    https://www.uptodate.com/contents/prevention-of-endocarditis-antibiotic-prophylaxis-and-other-measures
    – Completely repaired congenital heart defect with prosthetic material or device (eg, septal closure device), during the first six months after surgical or transcatheter placement. […] – Repaired congenital heart disease with residual defect at the site or adjacent to the site of a prosthetic patch or prosthetic device. […] Antibiotic prophylaxis prior to surgery is warranted for patients undergoing certain invasive procedures to reduce the risk of surgical site infection. A key example is implantation of prosthetic heart valves (surgical or transcatheter), prosthetic intravascular material, or prosthetic intracardiac material; this intervention is beneficial for prevention of surgical site infection and might reduce the risk of early prosthetic valve endocarditis, although evidence is limited.
  • #33 Antibiotic Prophylaxis for Heart Patients | MouthHealthy – Oral Health Information from the ADA
    https://www.mouthhealthy.org/all-topics-a-z/antibiotic-prophylaxis-for-heart-patients
    Antibiotic prophylaxis is recommended for a small number of people who have specific heart conditions. […] Heart conditions that are present from birth, such as: Unrepaired cyanotic congenital heart disease, including people with palliative shunts and conduit. […] Defects repaired with a prosthetic material or devicewhether placed by surgery or catheter interventionduring the first six months after repair. […] Cases in which a heart defect has been repaired, but a residual defect remains at the site or adjacent to the site of the prosthetic patch or prosthetic device used for the repair.
  • #34 ENDOCARDITIS PROPHYLAXIS IN CONGENITAL HEART DISEASE | Harrison’s Manual of Medicine
    https://harrisons.unboundmedicine.com/harrisons/view/Harrisons-Manual-of-Medicine/623308/all/ENDOCARDITIS_PROPHYLAXIS_IN_CONGENITAL_HEART_DISEASE
    American Heart Association 2007 Guidelines recommend antibiotic prophylaxis only in specific pts with congenital heart disease, i.e., those who are to undergo a dental procedure associated with bacteremia who have: […] Unrepaired cyanotic congenital heart disease (e.g., tetralogy of Fallot) […] Repaired congenital heart disease with residual defects adjacent to site of a prosthetic patch or transcatheter device […] A history of complete repair of congenital defects with prosthetic material or a transcatheter device within the previous 6 months.
  • #35 Prevention of endocarditis: Antibiotic prophylaxis and other measures – UpToDate
    https://www.uptodate.com/contents/prevention-of-endocarditis-antibiotic-prophylaxis-and-other-measures
    Prevention of endocarditis: Antibiotic prophylaxis and other measures […] Measures for prevention of infective endocarditis (IE) are discussed here, including the clinical approach and rationale for antibiotic prophylaxis prior to dental procedures. […] The indications for IE prophylaxis in 2021 American Heart Association (AHA) guidelines are narrower than indications outlined in prior (AHA) guidelines. The approach of the 2023 European Society of Cardiology (ESC) guidelines is similar to that of the AHA guidelines. These guidelines take into consideration both patient-based and procedure-based risk factors for IE. […] Measures for prevention of IE include: […] – Maintenance of oral hygiene. […] – Antibiotic prophylaxis prior to invasive dental or invasive oral procedures. […] – Timely treatment of infections with pathogens likely to cause endocarditis.
  • #36 Endocarditis in Children with Heart Defects
    https://www.rch.org.au/cardiology/parent_info/Endocarditis_in_Children_with_Heart_Defects/
    Recently significant changes to the prophylaxis guidelines have been made with more restricted indications. […] Children at risk should establish and maintain the best possible oral health to reduce potential sources of bacteraemia which includes tooth brushing and regular dental review. […] Single dose antibiotic prophylaxis is now only recommended for children with the highest risk of adverse outcome of infective endocarditis (see Table 1). […] In certain individual circumstances, medical and dental practitioners may consider giving antibiotics to patients not covered by these revised guidelines including those who have received prophylaxis over their lifetime. Recommendations for individual patients should be discussed with the treating cardiologist. […] Cardiac Conditions for which endocarditis prophylaxis with dental procedures is reasonable include congenital heart disease (CHD) but only if it involves unrepaired cyanotic defects, including palliative shunts and conduits, repaired congenital heart defect with prosthetic material or device (surgical or catheter intervention) during the first 6 months after the procedure, and repaired defects with residual defect at the site or adjacent to the site of a prosthetic patch or prosthetic device. […] Recommended prophylaxis includes amoxicillin 50 mg/kg oral 1 hour before procedure (max. 2 g) and alternatives for those hypersensitive to penicillin. […] These guidelines are those currently endorsed by the Cardiac Society of Australia and New Zealand.
  • #37 Prevention of endocarditis: Antibiotic prophylaxis and other measures – UpToDate
    https://www.uptodate.com/contents/prevention-of-endocarditis-antibiotic-prophylaxis-and-other-measures
    For patients with history of IE and patent ductus arteriosus (PDA) without severe pulmonary hypertension closure is warranted to reduce endocardial injury related to the high-velocity shunt, which may be a nidus for IE. […] Patients with history of IE with successfully closed PDA or VSD should continue to receive antibiotic prophylaxis prior to dental procedures. […] Preventive measures to reduce the risk of infective endocarditis (IE) include: […] – Maintenance of oral hygiene. […] – Timely treatment of infections with pathogens that cause endocarditis. […] – Antibiotic prophylaxis prior to invasive dental or invasive oral procedures. […] – Antibiotic prophylaxis prior to surgery reduces the risk of surgical site infection, as discussed separately, which may reduce the risk of subsequent endocarditis. […] – Closure of a patent ductus arteriosus (PDA) or ventricular septal defect (VSD).
  • #38 Endocarditis in Children with Heart Defects
    https://www.rch.org.au/cardiology/parent_info/Endocarditis_in_Children_with_Heart_Defects/
    Recently significant changes to the prophylaxis guidelines have been made with more restricted indications. […] Children at risk should establish and maintain the best possible oral health to reduce potential sources of bacteraemia which includes tooth brushing and regular dental review. […] Single dose antibiotic prophylaxis is now only recommended for children with the highest risk of adverse outcome of infective endocarditis (see Table 1). […] In certain individual circumstances, medical and dental practitioners may consider giving antibiotics to patients not covered by these revised guidelines including those who have received prophylaxis over their lifetime. Recommendations for individual patients should be discussed with the treating cardiologist. […] Cardiac Conditions for which endocarditis prophylaxis with dental procedures is reasonable include congenital heart disease (CHD) but only if it involves unrepaired cyanotic defects, including palliative shunts and conduits, repaired congenital heart defect with prosthetic material or device (surgical or catheter intervention) during the first 6 months after the procedure, and repaired defects with residual defect at the site or adjacent to the site of a prosthetic patch or prosthetic device. […] Recommended prophylaxis includes amoxicillin 50 mg/kg oral 1 hour before procedure (max. 2 g) and alternatives for those hypersensitive to penicillin. […] These guidelines are those currently endorsed by the Cardiac Society of Australia and New Zealand.
  • #39
    https://link.springer.com/article/10.1007/s11886-024-02103-9
    Present an updated overview of the prevention, diagnosis, and management of infective endocarditis in adult patients with congenital heart disease. […] Special considerations for antibiotic prophylaxis and management must be made for specific congenital heart diseases in adulthood and pregnant ACHD patients. […] There are several domains that encompass preventive measures in ACHD including education, proper oral hygiene, skin care, and antibiotic prophylaxis. […] Providers caring for ACHD patients should continually discuss with them the potential lifelong risk of IE including its clinical presentation and importance of early diagnosis. […] A significant proportion of patients with CHD are unaware of the correlation between oral health and heart disease. […] The American College of Cardiology (ACC) and the AHA recommend meticulous oral care and routine preventive care by a dentist or oral hygienist for patients with CHD.
  • #40
    https://link.springer.com/article/10.1007/s11886-024-02103-9
    The ESC also expresses concern about body piercing and susceptibility for the acquisition of IE. […] It is recommended to avoid tattooing and piercing by the 2023 ESC Guidelines. […] Antibiotic prophylaxis (AP) is used to prevent IE in patients at high risk undergoing invasive dental procedures. […] The AHA and the ACC recommends AP for patients with underlying cardiac conditions associated with the highest risk of adverse outcome from IE, such as those with a prosthetic heart valve, a past history of IE, unrepaired cyanotic congenital heart disease, residual shunt adjacent to prosthetic material, and cardiac valvulopathy following cardiac transplantation. […] For optimal effect, antibiotic prophylaxis should be administered 30-60 min prior to the procedure. […] In addition to reducing the incidence of IE, AP is also cost-effective, particularly for high-risk patients.
  • #41 Prevention of endocarditis: Antibiotic prophylaxis and other measures – UpToDate
    https://www.uptodate.com/contents/prevention-of-endocarditis-antibiotic-prophylaxis-and-other-measures
    For patients with history of IE and patent ductus arteriosus (PDA) without severe pulmonary hypertension closure is warranted to reduce endocardial injury related to the high-velocity shunt, which may be a nidus for IE. […] Patients with history of IE with successfully closed PDA or VSD should continue to receive antibiotic prophylaxis prior to dental procedures. […] Preventive measures to reduce the risk of infective endocarditis (IE) include: […] – Maintenance of oral hygiene. […] – Timely treatment of infections with pathogens that cause endocarditis. […] – Antibiotic prophylaxis prior to invasive dental or invasive oral procedures. […] – Antibiotic prophylaxis prior to surgery reduces the risk of surgical site infection, as discussed separately, which may reduce the risk of subsequent endocarditis. […] – Closure of a patent ductus arteriosus (PDA) or ventricular septal defect (VSD).
  • #42 Prevention of endocarditis: Antibiotic prophylaxis and other measures – UpToDate
    https://www.uptodate.com/contents/prevention-of-endocarditis-antibiotic-prophylaxis-and-other-measures
    For patients with history of IE and patent ductus arteriosus (PDA) without severe pulmonary hypertension closure is warranted to reduce endocardial injury related to the high-velocity shunt, which may be a nidus for IE. […] Patients with history of IE with successfully closed PDA or VSD should continue to receive antibiotic prophylaxis prior to dental procedures. […] Preventive measures to reduce the risk of infective endocarditis (IE) include: […] – Maintenance of oral hygiene. […] – Timely treatment of infections with pathogens that cause endocarditis. […] – Antibiotic prophylaxis prior to invasive dental or invasive oral procedures. […] – Antibiotic prophylaxis prior to surgery reduces the risk of surgical site infection, as discussed separately, which may reduce the risk of subsequent endocarditis. […] – Closure of a patent ductus arteriosus (PDA) or ventricular septal defect (VSD).
  • #43
    https://link.springer.com/article/10.1007/s11886-024-02103-9
    Present an updated overview of the prevention, diagnosis, and management of infective endocarditis in adult patients with congenital heart disease. […] Special considerations for antibiotic prophylaxis and management must be made for specific congenital heart diseases in adulthood and pregnant ACHD patients. […] There are several domains that encompass preventive measures in ACHD including education, proper oral hygiene, skin care, and antibiotic prophylaxis. […] Providers caring for ACHD patients should continually discuss with them the potential lifelong risk of IE including its clinical presentation and importance of early diagnosis. […] A significant proportion of patients with CHD are unaware of the correlation between oral health and heart disease. […] The American College of Cardiology (ACC) and the AHA recommend meticulous oral care and routine preventive care by a dentist or oral hygienist for patients with CHD.
  • #44 Prophylaxis protects infants with congenital heart disease from severe forms of RSV infection: an Italian observational retrospective study | Italian Journal of Pediatrics | Full Text
    https://ijponline.biomedcentral.com/articles/10.1186/s13052-022-01399-z
    Palivizumab prophylaxis in children with congenital heart disease (CHD) respiratory syncytial virus (RSV) infection may have a severe course, with increased risk of morbidity and mortality, requiring hospital admission and intensive care. […] The aim of the present study was to evaluate the effect of prophylaxis with palivizumab in preventing RSV-associated hospitalization in infants with CHD. […] Our study provides evidence of the efficacy of palivizumab in protecting patients with hemodynamically significant CHD under the age of 2 years from RSV disease and its life-threatening complications. […] Reducing hospitalisation rate, morbidity, and mortality in this category of patients, passive immune prophylaxis with palivizumab may impact healthcare resource availability and utilisation.
  • #45 Prophylaxis protects infants with congenital heart disease from severe forms of RSV infection: an Italian observational retrospective study | Italian Journal of Pediatrics | Full Text
    https://ijponline.biomedcentral.com/articles/10.1186/s13052-022-01399-z
    Palivizumab prophylaxis in children with congenital heart disease (CHD) respiratory syncytial virus (RSV) infection may have a severe course, with increased risk of morbidity and mortality, requiring hospital admission and intensive care. […] The aim of the present study was to evaluate the effect of prophylaxis with palivizumab in preventing RSV-associated hospitalization in infants with CHD. […] Our study provides evidence of the efficacy of palivizumab in protecting patients with hemodynamically significant CHD under the age of 2 years from RSV disease and its life-threatening complications. […] Reducing hospitalisation rate, morbidity, and mortality in this category of patients, passive immune prophylaxis with palivizumab may impact healthcare resource availability and utilisation.
  • #46 Prophylaxis protects infants with congenital heart disease from severe forms of RSV infection: an Italian observational retrospective study | Italian Journal of Pediatrics | Full Text
    https://ijponline.biomedcentral.com/articles/10.1186/s13052-022-01399-z
    In Italy, prophylaxis with palivizumab is recommended, as indicated by regulatory authority (Regione Emilia-Romagna) and scientific societies (Italian Society of Neonatology, Italian Society of Pediatric Cardiology and Congenital heart Diseases) in children under the age of 2 years with hemodynamically significant CHD (HS-CHD), with congestive heart failure that requires medical therapy, cyanosis with systemic saturation less than 90%, or pulmonary hypertension, and in children post cardiac transplantation; prophylaxis in the 2nd year of life is recommended when there is still a need of medical therapy on an ongoing basis. […] This study shows the shielding effect of palivizumab prophylaxis on patients with HS-CHD. […] Data confirm that up to now, palivizumab prophylaxis protects CHD from RSV infection and may be the best strategy for control of morbidity and mortality.
  • #47 Prophylaxis protects infants with congenital heart disease from severe forms of RSV infection: an Italian observational retrospective study | Italian Journal of Pediatrics | Full Text
    https://ijponline.biomedcentral.com/articles/10.1186/s13052-022-01399-z
    In Italy, prophylaxis with palivizumab is recommended, as indicated by regulatory authority (Regione Emilia-Romagna) and scientific societies (Italian Society of Neonatology, Italian Society of Pediatric Cardiology and Congenital heart Diseases) in children under the age of 2 years with hemodynamically significant CHD (HS-CHD), with congestive heart failure that requires medical therapy, cyanosis with systemic saturation less than 90%, or pulmonary hypertension, and in children post cardiac transplantation; prophylaxis in the 2nd year of life is recommended when there is still a need of medical therapy on an ongoing basis. […] This study shows the shielding effect of palivizumab prophylaxis on patients with HS-CHD. […] Data confirm that up to now, palivizumab prophylaxis protects CHD from RSV infection and may be the best strategy for control of morbidity and mortality.
  • #48 Prophylaxis protects infants with congenital heart disease from severe forms of RSV infection: an Italian observational retrospective study | Italian Journal of Pediatrics | Full Text
    https://ijponline.biomedcentral.com/articles/10.1186/s13052-022-01399-z
    Palivizumab prophylaxis in children with congenital heart disease (CHD) respiratory syncytial virus (RSV) infection may have a severe course, with increased risk of morbidity and mortality, requiring hospital admission and intensive care. […] The aim of the present study was to evaluate the effect of prophylaxis with palivizumab in preventing RSV-associated hospitalization in infants with CHD. […] Our study provides evidence of the efficacy of palivizumab in protecting patients with hemodynamically significant CHD under the age of 2 years from RSV disease and its life-threatening complications. […] Reducing hospitalisation rate, morbidity, and mortality in this category of patients, passive immune prophylaxis with palivizumab may impact healthcare resource availability and utilisation.
  • #49 CHD | RSV prophylaxis guideline changes and outcomes in children with congenital heart disease
    https://www.techscience.com/chd/v13n3/38997
    Objective: The aim of this study was to compare inpatient outcomes and costs for children with respiratory syncytial virus and congenital heart disease before and after the change in management guidelines for respiratory syncytial virus prophylaxis. […] Prior to 2014, children aged 0-24 months with congenital heart disease were eligible to receive respiratory syncytial virus prophylaxis. Updated guidelines, published in 2014, restricted the recommendation to administer palivizumab respiratory syncytial virus prophylaxis to children with congenital heart disease only if they are 12 months old. […] Our findings provide additional support for the new guideline recommendations to provide respiratory syncytial virus prophylaxis only for children 12 months old with congenital heart disease.
  • #50 Adult Congenital Heart Disease Clinic | UCSF Health
    https://www.ucsfhealth.org/clinics/adult-congenital-heart-disease-clinic
    While most adults with congenital heart disease lead full and active lives, you may experience lifelong problems related to your heart defect, including abnormal heart rhythms, heart failure or deterioration of heart repair done in childhood. […] The UCSF Adult Congenital Heart Disease Clinic offers comprehensive care that includes early detection of problems, treatment to prevent complications and surgical repair of defects. […] For adults with congenital heart disease, at least one visit at a center focused on the disease is recommended. […] For people with mild levels of disease, regular monitoring of the defect and heart function may be the only treatment necessary. […] If you’re pregnant or considering pregnancy, our Cardio-Obstetrics team provides specialized prenatal and preconception care for women with heart disease.
  • #51 Congenital Heart Disease in Adults: Types, Symptoms, and TreatmentHealthline
    https://www.healthline.com/health/congenital-heart-disease-in-adults
    Although you may not be able to prevent congenital heart disease, you can take steps as an adult to help prevent or lower your risk of further health complications. […] For example, you could: […] Exercise regularly under the guidance of your doctor or a cardiac rehabilitation specialist. […] Follow a heart-healthy eating plan, such as the Mediterranean diet or the Dietary Approaches to Stop Hypertension diet. […] Get regular checkups for your heart and your overall health. […] Maintain a moderate body weight that’s healthy for you. […] Manage your blood pressure, cholesterol, and blood sugar levels. […] Stop smoking, if applicable.
  • #52 Congenital Heart Disease in Adults: Types, Symptoms, and TreatmentHealthline
    https://www.healthline.com/health/congenital-heart-disease-in-adults
    Although you may not be able to prevent congenital heart disease, you can take steps as an adult to help prevent or lower your risk of further health complications. […] For example, you could: […] Exercise regularly under the guidance of your doctor or a cardiac rehabilitation specialist. […] Follow a heart-healthy eating plan, such as the Mediterranean diet or the Dietary Approaches to Stop Hypertension diet. […] Get regular checkups for your heart and your overall health. […] Maintain a moderate body weight that’s healthy for you. […] Manage your blood pressure, cholesterol, and blood sugar levels. […] Stop smoking, if applicable.
  • #53 Congenital Heart Disease in Adults: Types, Symptoms, and TreatmentHealthline
    https://www.healthline.com/health/congenital-heart-disease-in-adults
    Although you may not be able to prevent congenital heart disease, you can take steps as an adult to help prevent or lower your risk of further health complications. […] For example, you could: […] Exercise regularly under the guidance of your doctor or a cardiac rehabilitation specialist. […] Follow a heart-healthy eating plan, such as the Mediterranean diet or the Dietary Approaches to Stop Hypertension diet. […] Get regular checkups for your heart and your overall health. […] Maintain a moderate body weight that’s healthy for you. […] Manage your blood pressure, cholesterol, and blood sugar levels. […] Stop smoking, if applicable.
  • #54 Congenital Heart Disease in Adults: Types, Symptoms, and TreatmentHealthline
    https://www.healthline.com/health/congenital-heart-disease-in-adults
    Although you may not be able to prevent congenital heart disease, you can take steps as an adult to help prevent or lower your risk of further health complications. […] For example, you could: […] Exercise regularly under the guidance of your doctor or a cardiac rehabilitation specialist. […] Follow a heart-healthy eating plan, such as the Mediterranean diet or the Dietary Approaches to Stop Hypertension diet. […] Get regular checkups for your heart and your overall health. […] Maintain a moderate body weight that’s healthy for you. […] Manage your blood pressure, cholesterol, and blood sugar levels. […] Stop smoking, if applicable.
  • #55 Congenital Heart Disease in Adults: Types, Symptoms, and TreatmentHealthline
    https://www.healthline.com/health/congenital-heart-disease-in-adults
    Although you may not be able to prevent congenital heart disease, you can take steps as an adult to help prevent or lower your risk of further health complications. […] For example, you could: […] Exercise regularly under the guidance of your doctor or a cardiac rehabilitation specialist. […] Follow a heart-healthy eating plan, such as the Mediterranean diet or the Dietary Approaches to Stop Hypertension diet. […] Get regular checkups for your heart and your overall health. […] Maintain a moderate body weight that’s healthy for you. […] Manage your blood pressure, cholesterol, and blood sugar levels. […] Stop smoking, if applicable.
  • #56 Congenital Heart Disease in Adults: Types, Symptoms, and TreatmentHealthline
    https://www.healthline.com/health/congenital-heart-disease-in-adults
    Although you may not be able to prevent congenital heart disease, you can take steps as an adult to help prevent or lower your risk of further health complications. […] For example, you could: […] Exercise regularly under the guidance of your doctor or a cardiac rehabilitation specialist. […] Follow a heart-healthy eating plan, such as the Mediterranean diet or the Dietary Approaches to Stop Hypertension diet. […] Get regular checkups for your heart and your overall health. […] Maintain a moderate body weight that’s healthy for you. […] Manage your blood pressure, cholesterol, and blood sugar levels. […] Stop smoking, if applicable.
  • #57 Statin therapy prescribed less often in adult congenital heart disease
    https://www.healio.com/news/cardiology/20180227/statin-therapy-prescribed-less-often-in-adult-congenital-heart-disease
    Adults with congenital heart disease were less likely to be prescribed statin therapy for primary prevention compared with those without the condition regardless of 10-year atherosclerotic CVD risk scores, according to a study published in The American Journal of Cardiology. […] „As the [adults with congenital heart disease] population is living longer, ASCVD has increasing implications on their overall health. Primary care physicians, primary cardiologists and ASCVD cardiologists alike must engage in active surveillance of ASCVD risk factors and prioritize guideline-based primary prevention in this population to further mitigate ASCVD risk.” […] Statin therapy was appropriately prescribed to 42.3% of patients with congenital heart disease compared with 59% in the control group. […] „It is possible that shorter life expectancy of patients with [adult congenital heart disease] makes primary prevention of ASCVD seem less important. Additionally, the better control of risk factors such as LDL, obesity and smoking in patients with [adult congenital heart disease] as compared with their peers may influence the perception of risk and decision, consciously or subconsciously, to not initiate statin or aspirin therapy.”
  • #58 Statin therapy prescribed less often in adult congenital heart disease
    https://www.healio.com/news/cardiology/20180227/statin-therapy-prescribed-less-often-in-adult-congenital-heart-disease
    Adults with congenital heart disease were less likely to be prescribed statin therapy for primary prevention compared with those without the condition regardless of 10-year atherosclerotic CVD risk scores, according to a study published in The American Journal of Cardiology. […] „As the [adults with congenital heart disease] population is living longer, ASCVD has increasing implications on their overall health. Primary care physicians, primary cardiologists and ASCVD cardiologists alike must engage in active surveillance of ASCVD risk factors and prioritize guideline-based primary prevention in this population to further mitigate ASCVD risk.” […] Statin therapy was appropriately prescribed to 42.3% of patients with congenital heart disease compared with 59% in the control group. […] „It is possible that shorter life expectancy of patients with [adult congenital heart disease] makes primary prevention of ASCVD seem less important. Additionally, the better control of risk factors such as LDL, obesity and smoking in patients with [adult congenital heart disease] as compared with their peers may influence the perception of risk and decision, consciously or subconsciously, to not initiate statin or aspirin therapy.”
  • #59
    https://link.springer.com/article/10.1007/s11883-022-01034-6
    There are unique considerations for ASCVD risk reduction in ACHD patients. […] Preventative strategies for ASCVD are underutilized in ACHD patients. As these patients are followed for a lifetime by cardiologists, we can truly pursue primary prevention in this aging population. […] This paper indicated that ACHD patients have a similar ASCVD risk score than controls, but were less likely to be prescribed statins for primary prevention compared to peers.
  • #60 Statin therapy prescribed less often in adult congenital heart disease
    https://www.healio.com/news/cardiology/20180227/statin-therapy-prescribed-less-often-in-adult-congenital-heart-disease
    Adults with congenital heart disease were less likely to be prescribed statin therapy for primary prevention compared with those without the condition regardless of 10-year atherosclerotic CVD risk scores, according to a study published in The American Journal of Cardiology. […] „As the [adults with congenital heart disease] population is living longer, ASCVD has increasing implications on their overall health. Primary care physicians, primary cardiologists and ASCVD cardiologists alike must engage in active surveillance of ASCVD risk factors and prioritize guideline-based primary prevention in this population to further mitigate ASCVD risk.” […] Statin therapy was appropriately prescribed to 42.3% of patients with congenital heart disease compared with 59% in the control group. […] „It is possible that shorter life expectancy of patients with [adult congenital heart disease] makes primary prevention of ASCVD seem less important. Additionally, the better control of risk factors such as LDL, obesity and smoking in patients with [adult congenital heart disease] as compared with their peers may influence the perception of risk and decision, consciously or subconsciously, to not initiate statin or aspirin therapy.”
  • #61 Statin therapy prescribed less often in adult congenital heart disease
    https://www.healio.com/news/cardiology/20180227/statin-therapy-prescribed-less-often-in-adult-congenital-heart-disease
    Adults with congenital heart disease were less likely to be prescribed statin therapy for primary prevention compared with those without the condition regardless of 10-year atherosclerotic CVD risk scores, according to a study published in The American Journal of Cardiology. […] „As the [adults with congenital heart disease] population is living longer, ASCVD has increasing implications on their overall health. Primary care physicians, primary cardiologists and ASCVD cardiologists alike must engage in active surveillance of ASCVD risk factors and prioritize guideline-based primary prevention in this population to further mitigate ASCVD risk.” […] Statin therapy was appropriately prescribed to 42.3% of patients with congenital heart disease compared with 59% in the control group. […] „It is possible that shorter life expectancy of patients with [adult congenital heart disease] makes primary prevention of ASCVD seem less important. Additionally, the better control of risk factors such as LDL, obesity and smoking in patients with [adult congenital heart disease] as compared with their peers may influence the perception of risk and decision, consciously or subconsciously, to not initiate statin or aspirin therapy.”
  • #62 Specialized Follow-Up Care for Adults with Congenital Heart Disease | Duke Health
    https://www.dukehealth.org/blog/congenital-heart-disease-specialized-follow-up-care
    If you are among the millions of people living with ACHD, seeking routine follow-up care at a specialized heart center like Duke that is accredited by the Adult Congenital Heart Association can help you live a longer, healthier life. […] By maintaining regular follow-up appointments at an ACHD center like Dukes, you can correct problems early on or prevent them altogether. […] Whether you need guidance with disease prevention (how to eat healthier, exercise, or quit smoking), or if you need more advanced medical or surgical care, theres not a treatment or surgery that we dont provide. […] When we follow-up on your health carefully, in an organized fashion, we can help you live the life that you want to live.
  • #63 Specialized Follow-Up Care for Adults with Congenital Heart Disease | Duke Health
    https://www.dukehealth.org/blog/congenital-heart-disease-specialized-follow-up-care
    If you are among the millions of people living with ACHD, seeking routine follow-up care at a specialized heart center like Duke that is accredited by the Adult Congenital Heart Association can help you live a longer, healthier life. […] By maintaining regular follow-up appointments at an ACHD center like Dukes, you can correct problems early on or prevent them altogether. […] Whether you need guidance with disease prevention (how to eat healthier, exercise, or quit smoking), or if you need more advanced medical or surgical care, theres not a treatment or surgery that we dont provide. […] When we follow-up on your health carefully, in an organized fashion, we can help you live the life that you want to live.
  • #64 Specialized Follow-Up Care for Adults with Congenital Heart Disease | Duke Health
    https://www.dukehealth.org/blog/congenital-heart-disease-specialized-follow-up-care
    If you are among the millions of people living with ACHD, seeking routine follow-up care at a specialized heart center like Duke that is accredited by the Adult Congenital Heart Association can help you live a longer, healthier life. […] By maintaining regular follow-up appointments at an ACHD center like Dukes, you can correct problems early on or prevent them altogether. […] Whether you need guidance with disease prevention (how to eat healthier, exercise, or quit smoking), or if you need more advanced medical or surgical care, theres not a treatment or surgery that we dont provide. […] When we follow-up on your health carefully, in an organized fashion, we can help you live the life that you want to live.
  • #65 Specialized Follow-Up Care for Adults with Congenital Heart Disease | Duke Health
    https://www.dukehealth.org/blog/congenital-heart-disease-specialized-follow-up-care
    If you are among the millions of people living with ACHD, seeking routine follow-up care at a specialized heart center like Duke that is accredited by the Adult Congenital Heart Association can help you live a longer, healthier life. […] By maintaining regular follow-up appointments at an ACHD center like Dukes, you can correct problems early on or prevent them altogether. […] Whether you need guidance with disease prevention (how to eat healthier, exercise, or quit smoking), or if you need more advanced medical or surgical care, theres not a treatment or surgery that we dont provide. […] When we follow-up on your health carefully, in an organized fashion, we can help you live the life that you want to live.
  • #66 Adult Congenital Heart Disease Clinic | UCSF Health
    https://www.ucsfhealth.org/clinics/adult-congenital-heart-disease-clinic
    While most adults with congenital heart disease lead full and active lives, you may experience lifelong problems related to your heart defect, including abnormal heart rhythms, heart failure or deterioration of heart repair done in childhood. […] The UCSF Adult Congenital Heart Disease Clinic offers comprehensive care that includes early detection of problems, treatment to prevent complications and surgical repair of defects. […] For adults with congenital heart disease, at least one visit at a center focused on the disease is recommended. […] For people with mild levels of disease, regular monitoring of the defect and heart function may be the only treatment necessary. […] If you’re pregnant or considering pregnancy, our Cardio-Obstetrics team provides specialized prenatal and preconception care for women with heart disease.
  • #67 Azthena logo with the word Azthena
    https://www.news-medical.net/news/20190806/New-collaboration-to-advance-diagnosis-and-prevention-of-congenital-heart-defects.aspx
    The Children’s Heart Foundation, the nation’s leading organization dedicated to funding congenital heart research, has announced a new partnership to advance the diagnosis, treatment, and prevention of congenital heart defects. […] Improving outcomes for patients with congenital heart disease requires scientific discovery focused not only on the short-term but on key outcomes across the lifespan, and efforts to translate new science into tangible improvements in care at the bedside. […] Through the new collaboration between The Children’s Heart Foundation and Cardiac Networks United, organization leaders strive to make a lasting impact on the lives of patients and families impacted by congenital heart disease. […] „This partnership means very simply that researchers in the congenital heart space will be able to access the data needed to move the most promising and impactful research forward in a quicker, more efficient manner,” said Barbara Newhouse, CEO of The Children’s Heart Foundation. „And that means saving more children as well as having those same children grow into young adults who are living with a strong quality of life.”
  • #68 Azthena logo with the word Azthena
    https://www.news-medical.net/news/20190806/New-collaboration-to-advance-diagnosis-and-prevention-of-congenital-heart-defects.aspx
    The Children’s Heart Foundation, the nation’s leading organization dedicated to funding congenital heart research, has announced a new partnership to advance the diagnosis, treatment, and prevention of congenital heart defects. […] Improving outcomes for patients with congenital heart disease requires scientific discovery focused not only on the short-term but on key outcomes across the lifespan, and efforts to translate new science into tangible improvements in care at the bedside. […] Through the new collaboration between The Children’s Heart Foundation and Cardiac Networks United, organization leaders strive to make a lasting impact on the lives of patients and families impacted by congenital heart disease. […] „This partnership means very simply that researchers in the congenital heart space will be able to access the data needed to move the most promising and impactful research forward in a quicker, more efficient manner,” said Barbara Newhouse, CEO of The Children’s Heart Foundation. „And that means saving more children as well as having those same children grow into young adults who are living with a strong quality of life.”
  • #69 Azthena logo with the word Azthena
    https://www.news-medical.net/news/20190806/New-collaboration-to-advance-diagnosis-and-prevention-of-congenital-heart-defects.aspx
    The Children’s Heart Foundation, the nation’s leading organization dedicated to funding congenital heart research, has announced a new partnership to advance the diagnosis, treatment, and prevention of congenital heart defects. […] Improving outcomes for patients with congenital heart disease requires scientific discovery focused not only on the short-term but on key outcomes across the lifespan, and efforts to translate new science into tangible improvements in care at the bedside. […] Through the new collaboration between The Children’s Heart Foundation and Cardiac Networks United, organization leaders strive to make a lasting impact on the lives of patients and families impacted by congenital heart disease. […] „This partnership means very simply that researchers in the congenital heart space will be able to access the data needed to move the most promising and impactful research forward in a quicker, more efficient manner,” said Barbara Newhouse, CEO of The Children’s Heart Foundation. „And that means saving more children as well as having those same children grow into young adults who are living with a strong quality of life.”
  • #70 Azthena logo with the word Azthena
    https://www.news-medical.net/news/20190806/New-collaboration-to-advance-diagnosis-and-prevention-of-congenital-heart-defects.aspx
    The Children’s Heart Foundation, the nation’s leading organization dedicated to funding congenital heart research, has announced a new partnership to advance the diagnosis, treatment, and prevention of congenital heart defects. […] Improving outcomes for patients with congenital heart disease requires scientific discovery focused not only on the short-term but on key outcomes across the lifespan, and efforts to translate new science into tangible improvements in care at the bedside. […] Through the new collaboration between The Children’s Heart Foundation and Cardiac Networks United, organization leaders strive to make a lasting impact on the lives of patients and families impacted by congenital heart disease. […] „This partnership means very simply that researchers in the congenital heart space will be able to access the data needed to move the most promising and impactful research forward in a quicker, more efficient manner,” said Barbara Newhouse, CEO of The Children’s Heart Foundation. „And that means saving more children as well as having those same children grow into young adults who are living with a strong quality of life.”
  • #71 Azthena logo with the word Azthena
    https://www.news-medical.net/news/20190806/New-collaboration-to-advance-diagnosis-and-prevention-of-congenital-heart-defects.aspx
    The Children’s Heart Foundation, the nation’s leading organization dedicated to funding congenital heart research, has announced a new partnership to advance the diagnosis, treatment, and prevention of congenital heart defects. […] Improving outcomes for patients with congenital heart disease requires scientific discovery focused not only on the short-term but on key outcomes across the lifespan, and efforts to translate new science into tangible improvements in care at the bedside. […] Through the new collaboration between The Children’s Heart Foundation and Cardiac Networks United, organization leaders strive to make a lasting impact on the lives of patients and families impacted by congenital heart disease. […] „This partnership means very simply that researchers in the congenital heart space will be able to access the data needed to move the most promising and impactful research forward in a quicker, more efficient manner,” said Barbara Newhouse, CEO of The Children’s Heart Foundation. „And that means saving more children as well as having those same children grow into young adults who are living with a strong quality of life.”