Materiały źródłowe

• #1 Hairy Cell Leukemia | NYU Langone Health

  https://nyulangone.org/conditions/hairy-cell-leukemia

  Hairy cell leukemia is a cancer of a type of white blood cell that originates in the bone marrow, the soft spongy tissue located in the center of bones throughout the body. It is a rare, slow-growing cancer that affects white blood cells called B lymphocytes. Healthy B lymphocytes make antibodiesproteins that fight infection in the body. […] In people with hairy cell leukemia, the bone marrow produces abnormal B lymphocytes. These cells have tiny hairlike projections, giving the cancer its name. […] We provide ongoing, compassionate care and monitoring for people with hairy cell leukemia. Our specialists use sophisticated tests to diagnose this chronic disease and create a personalized treatment plan to manage it. Treatment for hairy cell leukemia may include surgery as well as medication. Our team of oncologists, nurses, physical therapists, psychologists, and social workers can help enhance your wellbeing throughout treatment and recovery.

• #2 About Hairy Cell Leukemia (HCL) | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/leukemias/types/about-hairy-cell-leukemia-hcl

  Hairy cell leukemia (HCL) is a rare chronic leukemia in adults. Around 1,000 people in the United States develop HCL each year, according to the World Health Organization. The average age at diagnosis is 52. HCL is more common in men than in women. There is no clear evidence that HCL runs in families or is caused by specific environmental factors. […] Some people with HCL do not have any symptoms. For them, HCL is typically diagnosed during an evaluation for a low blood count. Among those who do have symptoms, the most common causes are an enlarged spleen and a low blood count. […] The recommended treatments for HCL vary. People who dont have symptoms or a low blood count may be observed for any changes during regular office visits and with laboratory tests. For those who need treatment, the typical goals are to restore a normal blood count and, if needed, to reduce the spleen size. […] People with HCL are likely to have regular checkups. Their doctor will monitor the disease and determine if it is growing. These visits may include a physical exam, blood tests, bone marrow aspirates, biopsies, and radiographic studies.

• #3 About Hairy Cell Leukemia (HCL) | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/leukemias/types/about-hairy-cell-leukemia-hcl

  Hairy cell leukemia (HCL) is a rare chronic leukemia in adults. Around 1,000 people in the United States develop HCL each year, according to the World Health Organization. The average age at diagnosis is 52. HCL is more common in men than in women. There is no clear evidence that HCL runs in families or is caused by specific environmental factors. […] Some people with HCL do not have any symptoms. For them, HCL is typically diagnosed during an evaluation for a low blood count. Among those who do have symptoms, the most common causes are an enlarged spleen and a low blood count. […] The recommended treatments for HCL vary. People who dont have symptoms or a low blood count may be observed for any changes during regular office visits and with laboratory tests. For those who need treatment, the typical goals are to restore a normal blood count and, if needed, to reduce the spleen size. […] People with HCL are likely to have regular checkups. Their doctor will monitor the disease and determine if it is growing. These visits may include a physical exam, blood tests, bone marrow aspirates, biopsies, and radiographic studies.

• #4 About Hairy Cell Leukemia (HCL) | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/leukemias/types/about-hairy-cell-leukemia-hcl

  Hairy cell leukemia (HCL) is a rare chronic leukemia in adults. Around 1,000 people in the United States develop HCL each year, according to the World Health Organization. The average age at diagnosis is 52. HCL is more common in men than in women. There is no clear evidence that HCL runs in families or is caused by specific environmental factors. […] Some people with HCL do not have any symptoms. For them, HCL is typically diagnosed during an evaluation for a low blood count. Among those who do have symptoms, the most common causes are an enlarged spleen and a low blood count. […] The recommended treatments for HCL vary. People who dont have symptoms or a low blood count may be observed for any changes during regular office visits and with laboratory tests. For those who need treatment, the typical goals are to restore a normal blood count and, if needed, to reduce the spleen size. […] People with HCL are likely to have regular checkups. Their doctor will monitor the disease and determine if it is growing. These visits may include a physical exam, blood tests, bone marrow aspirates, biopsies, and radiographic studies.

• #5 https://www.lls.org/leukemia/hairy-cell-leukemia

  https://www.lls.org/leukemia/hairy-cell-leukemia

  Hairy cells tend to accumulate in the bone marrow, liver and spleen. Even though hairy cell leukemia affects the white cells, the lymph nodes usually don’t enlarge. […] Hairy cells multiply uncontrollably and crowd out normal white cells, red cells and platelets. […] As a result, the number of healthy blood cells (red cells, white cells and platelets) is usually lower than normal. […] Anemia is a condition when there is a low number of red cells in the blood which can cause fatigue and shortness of breath. […] Neutropenia is a condition when there is a low number of white cells, so the immune system can’t effectively guard against infection due to a lack of neutrophils (a type of white cell). […] Thrombocytopenia is a condition when there is a low number of platelets which can cause bleeding and easy bruising with no apparent cause. […] Low numbers of all three blood cell counts is called pancytopenia.

• #6 https://www.lls.org/leukemia/hairy-cell-leukemia

  https://www.lls.org/leukemia/hairy-cell-leukemia

  Hairy cells tend to accumulate in the bone marrow, liver and spleen. Even though hairy cell leukemia affects the white cells, the lymph nodes usually don’t enlarge. […] Hairy cells multiply uncontrollably and crowd out normal white cells, red cells and platelets. […] As a result, the number of healthy blood cells (red cells, white cells and platelets) is usually lower than normal. […] Anemia is a condition when there is a low number of red cells in the blood which can cause fatigue and shortness of breath. […] Neutropenia is a condition when there is a low number of white cells, so the immune system can’t effectively guard against infection due to a lack of neutrophils (a type of white cell). […] Thrombocytopenia is a condition when there is a low number of platelets which can cause bleeding and easy bruising with no apparent cause. […] Low numbers of all three blood cell counts is called pancytopenia.

• #7 Leukemia: Nursing Diagnoses, Care Plans, Assessment & Interventions | NurseTogether

  https://www.nursetogether.com/leukemia-nursing-diagnosis-care-plan/

  Leukemia can cause an overwhelming sense of exhaustion or fatigue which affects the patient mentally and physically. Like other blood cancers, leukemia can directly cause anemia which prevents the bone marrow from producing healthy and normal blood cells to support oxygenation. […] Patients with leukemia are at risk for imbalanced fluid volume caused by symptoms of the disease and/or treatments. […] Patients with leukemia are at risk for developing infections as they have a low white blood cell count and a compromised immune system. In addition, cancer treatments like chemotherapy can destroy both cancer and healthy infection-fighting white blood cells.

• #8 Leukemia: Nursing Diagnoses, Care Plans, Assessment & Interventions | NurseTogether

  https://www.nursetogether.com/leukemia-nursing-diagnosis-care-plan/

  Leukemia is a progressive condition and can be fatal if left untreated. While there is no cure for leukemia, attaining remission is a realistic option for some patients. Nurses support patients with leukemia by providing supportive care, especially for those who are undergoing chemotherapy, radiation, and other biologic therapies. It is essential to manage and prevent complications, provide comfort measures, patient and family education, and continuous emotional support. […] Nursing interventions and care are essential for the patients recovery. In the following section, you will learn more about possible nursing interventions for a patient with leukemia. […] Nursing care plans help prioritize assessments and interventions for both short and long-term goals of care. […] Bone pain is common in patients diagnosed with leukemia. Pain occurs when the bone marrow expands from the accumulation of abnormal white blood cells. This is commonly felt in the arms and legs. Chemotherapy also causes neuropathic pain described as tingling, numbness, and shooting sensation in the hands and feet.

• #9 Hairy Cell Leukemia – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK499845/

  Once treated, these patients need to be followed by the oncology nurse and primary care physician with regular monitoring of blood work. […] The interprofessional team can optimize the treatment of these patients through communication and coordination of care. Oncologists provide diagnoses and care plans. Nurse practitioners implement care and monitor treatment. Specialty care oncologic nurses should work with the team for coordination of care and are involved in patient education. […] Supportive care measures such as antimicrobial prophylaxis for viral and pneumocystis pneumonia should be considered for those with significant cytopenias. Patients should be educated about personal hygiene and the importance of handwashing.

• #10 8 Leukemia Nursing Care Plans – Nurseslabs

  https://nurseslabs.com/leukemia-nursing-care-plans/

  The nursing management and care plan for patients with leukemia involve several important aspects. Nurses play a crucial role in assessing and monitoring patients, managing symptoms, and providing support throughout the treatment journey. […] The following are the nursing priorities for patients with leukemia: Minimizing infection through infection control, Managing side effects of chemotherapy, Managing pain, Providing emotional support, Providing health teachings. […] Clients with leukemia are at risk for infection due to the diseases impact on the bone marrow and immune system. Leukemia disrupts the production of normal blood cells, including white blood cells that play a crucial role in fighting infections, leaving the body vulnerable to bacterial, fungal, and viral infections. […] Infection prevention strategies are essential in reducing the risk of complications and ensuring optimal treatment outcomes.

• #11 Hairy Cell Leukemia: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/23177-hairy-cell-leukemia

  Chemotherapy is the most common initial (first-line) treatment for people who have symptoms with hairy cell leukemia. Cladribine (Leustatin) or pentostatin (Nipent) are common initial anticancer drug treatments for this condition. […] All cancer treatments have side effects. In this case, the chemotherapy drugs that treat hairy cell leukemia increase your risk of infections that may be life-threatening. Your oncologist will explain what steps you can take to prevent infections. Theyll also tell you what changes in your body may be signs you have an infection. […] Hairy cell leukemia increases the chance youll develop infections that can be life-threatening. You can strengthen your immune system and protect yourself from infection. Here are some suggestions: Fill your plate with healthy foods: Fruits, veggies, lean sources of protein and whole grains are just some examples of foods that bolster immune function. Build activity into your daily routine: Daily activity helps many aspects of your health, including your immune system. Catch enough ZZZs: Not getting enough sleep can prevent your immune system from working as it should. Stay up-to-date on vaccines: Vaccines train your body to fight off germs that can make you sick. Talk to your provider about which vaccines you need and when.

• #12 8 Leukemia Nursing Care Plans – Nurseslabs

  https://nurseslabs.com/leukemia-nursing-care-plans/

  The nursing management and care plan for patients with leukemia involve several important aspects. Nurses play a crucial role in assessing and monitoring patients, managing symptoms, and providing support throughout the treatment journey. […] The following are the nursing priorities for patients with leukemia: Minimizing infection through infection control, Managing side effects of chemotherapy, Managing pain, Providing emotional support, Providing health teachings. […] Clients with leukemia are at risk for infection due to the diseases impact on the bone marrow and immune system. Leukemia disrupts the production of normal blood cells, including white blood cells that play a crucial role in fighting infections, leaving the body vulnerable to bacterial, fungal, and viral infections. […] Infection prevention strategies are essential in reducing the risk of complications and ensuring optimal treatment outcomes.

• #13 Hairy Cell Leukemia: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/23177-hairy-cell-leukemia

  Chemotherapy is the most common initial (first-line) treatment for people who have symptoms with hairy cell leukemia. Cladribine (Leustatin) or pentostatin (Nipent) are common initial anticancer drug treatments for this condition. […] All cancer treatments have side effects. In this case, the chemotherapy drugs that treat hairy cell leukemia increase your risk of infections that may be life-threatening. Your oncologist will explain what steps you can take to prevent infections. Theyll also tell you what changes in your body may be signs you have an infection. […] Hairy cell leukemia increases the chance youll develop infections that can be life-threatening. You can strengthen your immune system and protect yourself from infection. Here are some suggestions: Fill your plate with healthy foods: Fruits, veggies, lean sources of protein and whole grains are just some examples of foods that bolster immune function. Build activity into your daily routine: Daily activity helps many aspects of your health, including your immune system. Catch enough ZZZs: Not getting enough sleep can prevent your immune system from working as it should. Stay up-to-date on vaccines: Vaccines train your body to fight off germs that can make you sick. Talk to your provider about which vaccines you need and when.

• #14 Hairy Cell Leukemia: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/23177-hairy-cell-leukemia

  Hairy cell leukemia and treatments increase the chance youll have serious and sometimes life-threatening infections. Contact your healthcare provider if you have the following symptoms: A fever above 100.4 degrees Fahrenheit (38 degrees Celsius) that doesnt go away. A sore throat that lasts longer than a few days or gets worse. Abdominal pain that doesnt go away or gets worse. […] Ask your healthcare provider about vaccinations and other steps you can take to reduce infection risk.

• #15 Understanding Hairy Cell Leukemia — Hairy Cell Leukemia Foundation

  https://www.hairycellleukemia.org/hairy-cell-leukemia

  After treatment there is almost always a further, temporary fall in normal blood counts before they eventually recover. […] Both drugs are generally well tolerated but are associated with a temporary reduction in normal blood counts, which need to be monitored closely (weekly initially) until recovery. […] Patients with HCL should not receive the older Herpes Zoster (shingles) vaccine (called Zostavax) from their physicians, as it is a live virus vaccine that might result in causing the very condition that it is intended to prevent. […] Regular monitoring by a hematologist takes place, usually once or twice a year for patients in stable remission. […] Evaluation of the patient by a hematologist with experience in the management of hairy cell leukemia may enable the reason for the patients lack of response to be understood.

• #16 Hairy Cell Leukemia – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK499845/

  Once treated, these patients need to be followed by the oncology nurse and primary care physician with regular monitoring of blood work. […] The interprofessional team can optimize the treatment of these patients through communication and coordination of care. Oncologists provide diagnoses and care plans. Nurse practitioners implement care and monitor treatment. Specialty care oncologic nurses should work with the team for coordination of care and are involved in patient education. […] Supportive care measures such as antimicrobial prophylaxis for viral and pneumocystis pneumonia should be considered for those with significant cytopenias. Patients should be educated about personal hygiene and the importance of handwashing.

• #17 Hairy Cell Leukemia: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/23177-hairy-cell-leukemia

  Hairy cell leukemia and treatments increase the chance youll have serious and sometimes life-threatening infections. Contact your healthcare provider if you have the following symptoms: A fever above 100.4 degrees Fahrenheit (38 degrees Celsius) that doesnt go away. A sore throat that lasts longer than a few days or gets worse. Abdominal pain that doesnt go away or gets worse. […] Ask your healthcare provider about vaccinations and other steps you can take to reduce infection risk.

• #18 8 Leukemia Nursing Care Plans – Nurseslabs

  https://nurseslabs.com/leukemia-nursing-care-plans/

  Administering medications and providing pharmacologic support are essential components of the comprehensive care provided to patients with leukemia. […] Monitoring laboratory and diagnostic procedures is essential in the care of patients with leukemia. Regular monitoring of laboratory parameters and diagnostic procedures provides valuable information for treatment planning and management.

• #19 Hairy Cell Leukemia Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/200580-treatment

  Patients with hairy cell leukemia (HCL) who have stable peripheral blood cell counts may be observed closely on a watch-and-wait program that entails at least quarterly blood cell counts and physical examinations. […] If the blood cell counts show a sustained decline or the patient becomes symptomatic (ie, develops fatigue or splenomegaly), then therapy with a purine analogue is started before the counts decline to dangerously low levels. […] Blood cell counts may worsen temporarily after the initiation of either cladribine or pentostatin, so intervention should definitely begin before these hematologic parameters have deteriorated to levels requiring support. […] The data regarding the use of either pentostatin or cladribine alone for hairy cell leukemia suggest that these agents are equally effective in terms of response rate and remission duration.

• #20 Hairy cell leukemia – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/hairy-cell-leukemia/diagnosis-treatment/drc-20372962

  Hairy cell leukemia treatments are good at controlling the disease. But they can’t make it go away completely. Instead, treatments can control the cancer so that you can go about your life as usual. People with hairy cell leukemia can live with the disease for many years. […] Treatment for hairy cell leukemia doesn’t always need to start right away. This cancer often gets worse very slowly over time. You might choose to wait and have treatment if the cancer starts to cause symptoms. […] If you don’t have treatment, you’ll have regular appointments with your health care provider. You might have blood tests to see if hairy cell leukemia is getting worse. […] You might decide to start treatment if you start to get hairy cell leukemia symptoms. Most people with hairy cell leukemia will eventually need treatment.

• #21 Treating Hairy Cell Leukemia | American Cancer Society

  https://www.cancer.org/cancer/types/chronic-lymphocytic-leukemia/treating/hairy-cell-leukemia.html

  Hairy cell leukemia (HCL) tends to grow slowly. People with HCL who aren’t having symptoms often don’t need to be treated right away, but they do need to be watched carefully. […] If you have HCL, you will see your cancer care team every few months to check for signs that the HCL is growing and to see if it’s causing any problems (like low blood counts, fatigue, or an enlarged spleen). […] Treatment may be advised if you have low blood cell counts, recurrent infections, an enlarged spleen or lymph nodes, or other bothersome symptoms. […] Treatment doesn’t cure HCL, but it can help with symptoms, stop the HCL from progressing, and help you live longer. […] If you are uncomfortable because of an enlarged spleen, surgery to remove your spleen (splenectomy) can often help relieve pain. […] Like chronic lymphocytic leukemia (CLL), HCL can cause low blood counts and infections. Treatment of these problems is discussed in Supportive or Palliative Care for Chronic Lymphocytic Leukemia.

• #22 https://www.lls.org/leukemia/hairy-cell-leukemia/treatment/watch-and-wait

  https://www.lls.org/leukemia/hairy-cell-leukemia/treatment/watch-and-wait

  A small percentage of people can manage their hairy cell leukemia with their doctors using a watch-and-wait approach. […] By using the watch-and-wait method, your doctor can monitor your condition with regular physical exams and lab tests. […] You must visit your doctor regularly so he or she can check you for any health changes, specifically watching whether your disease remains stable or starts to progress. […] Your doctor monitors your test results to decide when it’s time to start treatment and what the best treatment option is for you.

• #23 Hairy cell leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/chronic-lymphocytic-leukemia-cll/treatment/hairy-cell-leukemia

  Hairy cell leukemia (HCL) is an uncommon type of lymphocytic leukemia that starts in B cells, or B lymphocytes (a type of white blood cell). […] HCL is usually slow growing (chronic), but it often progresses (gets worse). Most people will eventually need treatment. It is highly treatable but rarely cured. […] Treatment is usually given if HCL starts to progress. Signs that the disease is progressing include symptoms getting worse, low blood cell counts and frequent infections. […] Your healthcare team will create a treatment plan just for you. The plan is based on your health and specific information about the cancer. What you want is also important when planning treatment. […] Active observation means that your healthcare team watches the cancer closely for changes. […] If you start having symptoms or they get worse, such as your blood cell counts staying low or your spleen getting larger and more uncomfortable, your healthcare team may decide to start other treatment.

• #24 About Hairy Cell Leukemia (HCL) | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/leukemias/types/about-hairy-cell-leukemia-hcl

  Hairy cell leukemia (HCL) is a rare chronic leukemia in adults. Around 1,000 people in the United States develop HCL each year, according to the World Health Organization. The average age at diagnosis is 52. HCL is more common in men than in women. There is no clear evidence that HCL runs in families or is caused by specific environmental factors. […] Some people with HCL do not have any symptoms. For them, HCL is typically diagnosed during an evaluation for a low blood count. Among those who do have symptoms, the most common causes are an enlarged spleen and a low blood count. […] The recommended treatments for HCL vary. People who dont have symptoms or a low blood count may be observed for any changes during regular office visits and with laboratory tests. For those who need treatment, the typical goals are to restore a normal blood count and, if needed, to reduce the spleen size. […] People with HCL are likely to have regular checkups. Their doctor will monitor the disease and determine if it is growing. These visits may include a physical exam, blood tests, bone marrow aspirates, biopsies, and radiographic studies.

• #25 Hairy Cell Leukemia Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/200580-treatment

  One strategy involves starting treatment with interferon alfa, to obtain an improvement in the granulocyte count that may enable the antibiotic or antifungal therapy to be more effective in controlling the infection; this is followed by a definitive purine analog therapy to achieve complete remission. […] Complete remission rates with interferon only are low, at 11% in patients without infection and 5% in patients with infection. […] Alternatively, pentostatin may be used. […] Pentostatin is cleared by the kidneys, so kidney function must be carefully monitored during therapy. […] The standard criteria for initiating therapy for hairy cell leukemia (HCL) include the following: Symptoms or blood transfusion requirement, Significant anemia with hemoglobin of 8-10 g/dL or less, Thrombocytopenia with platelet counts of 50,000-100,000/mL or less, Neutropenia with an absolute neutrophil count (ANC) of 500-1000/mL or less.

• #26 Hairy Cell Leukemia Treatment (PDQ®) – NCI

  https://www.cancer.gov/types/leukemia/hp/hairy-cell-treatment-pdq

  Hairy cell leukemia is highly treatable but rarely cured. Because it is easily controlled, many patients have prolonged survival with the use of sequential therapies. The decision to treat is based on signs of disease progression, including any of the following factors: […] If the patient is asymptomatic and if blood counts are maintained in an acceptable range, therapy may not be needed. […] Cladribine, with or without rituximab, remains the standard of care. However, due to the risk of serious and prolonged immunosuppression, nonchemotherapy treatment options may be preferable for older, frail patients with higher risks of infection (or for those who have active infections). […] Treatment options for hairy cell leukemia include: […] Splenectomy plays a decreasing role in treating hairy cell leukemia because effective alternatives are available. Splenectomy will partially or completely normalize the peripheral blood in most patients with hairy cell leukemia. […] Interferon is useful when treating hairy cell leukemia during pregnancy because it does not involve cytotoxic agents.

• #27 Hairy cell leukemia – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/hairy-cell-leukemia/diagnosis-treatment/drc-20372962

  Chemotherapy is a drug treatment that uses powerful drugs to kill cancer cells. It’s often the first treatment for hairy cell leukemia. Chemotherapy is very effective for hairy cell leukemia. Most people get a complete or partial remission after chemotherapy. Remission means you have no signs of cancer. […] Chemotherapy for hairy cell leukemia can be given as a shot. Or it can be given as an infusion into a vein. […] If your hairy cell leukemia comes back, your provider might recommend repeating chemotherapy with the same drug or trying a different drug. Another option may be targeted drug therapy. […] Targeted drug treatments attack specific chemicals present within cancer cells. By blocking these chemicals, targeted drug treatments can cause cancer cells to die. […] Targeted drug therapy is sometimes used as a first treatment for hairy cell leukemia. It can be used with chemotherapy. More often, targeted therapy is an option if the cancer comes back after chemotherapy. […] Your health care provider will have your cancer cells tested to see whether targeted drug therapy is likely to work for you.

• #28 Hairy Cell Leukemia: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/23177-hairy-cell-leukemia

  Chemotherapy is the most common initial (first-line) treatment for people who have symptoms with hairy cell leukemia. Cladribine (Leustatin) or pentostatin (Nipent) are common initial anticancer drug treatments for this condition. […] All cancer treatments have side effects. In this case, the chemotherapy drugs that treat hairy cell leukemia increase your risk of infections that may be life-threatening. Your oncologist will explain what steps you can take to prevent infections. Theyll also tell you what changes in your body may be signs you have an infection. […] Hairy cell leukemia increases the chance youll develop infections that can be life-threatening. You can strengthen your immune system and protect yourself from infection. Here are some suggestions: Fill your plate with healthy foods: Fruits, veggies, lean sources of protein and whole grains are just some examples of foods that bolster immune function. Build activity into your daily routine: Daily activity helps many aspects of your health, including your immune system. Catch enough ZZZs: Not getting enough sleep can prevent your immune system from working as it should. Stay up-to-date on vaccines: Vaccines train your body to fight off germs that can make you sick. Talk to your provider about which vaccines you need and when.

• #29 Hairy cell leukaemia | Lymphoma Action

  https://lymphoma-action.org.uk/types-lymphoma/hairy-cell-leukaemia

  The most likely treatment for people with hairy cell leukaemia is chemotherapy. The most common chemotherapy drugs for hairy cell leukaemia are: Cladribine, which you have as an injection under your skin (subcutaneous injection) or through a drip into a vein (an intravenous infusion). Treatment is usually either given daily for up to 7 days, or once a week for 5 to 6 weeks. Pentostatin, which you have through a drip into a vein once every 2 to 3 weeks. You carry on having treatment until most of your blood counts return to normal levels, which is typically 4 to 5 months after starting treatment. […] As well as treatments to control the hairy cell leukaemia, you may have treatment to help relieve your symptoms or prevent infections. These might include: antibiotics and antiviral drugs to prevent or treat infections; annual vaccinations against flu and pneumonia; red blood cell transfusions or platelet transfusions to treat low blood counts; growth factor (G-CSF) injections to boost your white blood cell count if you have an infection.

• #30 Hairy Cell Leukemia Treatment (PDQ®): Treatment – Health Professional Information [NCI] | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.hairy-cell-leukemia-treatment-pdq%C2%AE-treatment-health-professional-information-nci.ncicdr0000062926

  Consider watchful waiting when feasible; asymptomatic patients with noncritical levels of pancytopenia can be monitored closely. […] Avoid using cladribine, with or without rituximab, and pentostatin because of the risk of serious and prolonged immunosuppression. […] In patients with relapsed disease, the previously mentioned options are available, along with ibrutinib (the Bruton tyrosine kinase inhibitor). […] Rituximab can induce durable remissions (with minimal toxic effects), but rarely complete remissions, in patients with multiple relapses or refractory disease after treatment with a purine analogue or interferon. […] Cladribine may be given with or without rituximab to treat hairy cell leukemia. […] Pentostatin given IV every other week for 3 to 6 months produced a 50% to 76% complete response rate and an 80% to 87% overall response rate.

• #31 Hairy Cell Leukemia Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/200580-treatment

  Patients with hairy cell leukemia (HCL) who have stable peripheral blood cell counts may be observed closely on a watch-and-wait program that entails at least quarterly blood cell counts and physical examinations. […] If the blood cell counts show a sustained decline or the patient becomes symptomatic (ie, develops fatigue or splenomegaly), then therapy with a purine analogue is started before the counts decline to dangerously low levels. […] Blood cell counts may worsen temporarily after the initiation of either cladribine or pentostatin, so intervention should definitely begin before these hematologic parameters have deteriorated to levels requiring support. […] The data regarding the use of either pentostatin or cladribine alone for hairy cell leukemia suggest that these agents are equally effective in terms of response rate and remission duration.

• #32 Understanding Hairy Cell Leukemia — Hairy Cell Leukemia Foundation

  https://www.hairycellleukemia.org/hairy-cell-leukemia

  After treatment there is almost always a further, temporary fall in normal blood counts before they eventually recover. […] Both drugs are generally well tolerated but are associated with a temporary reduction in normal blood counts, which need to be monitored closely (weekly initially) until recovery. […] Patients with HCL should not receive the older Herpes Zoster (shingles) vaccine (called Zostavax) from their physicians, as it is a live virus vaccine that might result in causing the very condition that it is intended to prevent. […] Regular monitoring by a hematologist takes place, usually once or twice a year for patients in stable remission. […] Evaluation of the patient by a hematologist with experience in the management of hairy cell leukemia may enable the reason for the patients lack of response to be understood.

• #33 Hairy Cell Leukemia Treatment & Management: Approach Considerations, Medical Care, Surgical Care

  https://emedicine.medscape.com/article/200580-treatment

  Substantial improvement in overall survival has been reported with initial use of either agent. […] Although close monitoring for late adverse effects of therapy is necessary, patients with hairy cell leukemia may now live as long as they would have without this diagnosis. […] In selecting appropriate chemotherapy, the following clinical questions must be considered: Is there evidence of active, untreated, ongoing infection? […] Although it is prudent to attempt to treat an active infection before starting purine analogue therapy in a patient with hairy cell leukemia, the profound neutropenia and monocytopenia from the disease may force the decision to start antileukemic therapy. […] The use of granulocyte colony-stimulating factor (G-CSF) can raise the absolute neutrophil count and shorten the period of severe neutropenia in hairy cell leukemia patients receiving cladribine, but routine use has not been shown to offer any clinical advantage.

• #34 Hairy cell leukemia – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/hairy-cell-leukemia/diagnosis-treatment/drc-20372962

  Chemotherapy is a drug treatment that uses powerful drugs to kill cancer cells. It’s often the first treatment for hairy cell leukemia. Chemotherapy is very effective for hairy cell leukemia. Most people get a complete or partial remission after chemotherapy. Remission means you have no signs of cancer. […] Chemotherapy for hairy cell leukemia can be given as a shot. Or it can be given as an infusion into a vein. […] If your hairy cell leukemia comes back, your provider might recommend repeating chemotherapy with the same drug or trying a different drug. Another option may be targeted drug therapy. […] Targeted drug treatments attack specific chemicals present within cancer cells. By blocking these chemicals, targeted drug treatments can cause cancer cells to die. […] Targeted drug therapy is sometimes used as a first treatment for hairy cell leukemia. It can be used with chemotherapy. More often, targeted therapy is an option if the cancer comes back after chemotherapy. […] Your health care provider will have your cancer cells tested to see whether targeted drug therapy is likely to work for you.

• #35 Hairy Cell Leukemia Treatment (PDQ®): Treatment – Health Professional Information [NCI] | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.hairy-cell-leukemia-treatment-pdq%C2%AE-treatment-health-professional-information-nci.ncicdr0000062926

  Consider watchful waiting when feasible; asymptomatic patients with noncritical levels of pancytopenia can be monitored closely. […] Avoid using cladribine, with or without rituximab, and pentostatin because of the risk of serious and prolonged immunosuppression. […] In patients with relapsed disease, the previously mentioned options are available, along with ibrutinib (the Bruton tyrosine kinase inhibitor). […] Rituximab can induce durable remissions (with minimal toxic effects), but rarely complete remissions, in patients with multiple relapses or refractory disease after treatment with a purine analogue or interferon. […] Cladribine may be given with or without rituximab to treat hairy cell leukemia. […] Pentostatin given IV every other week for 3 to 6 months produced a 50% to 76% complete response rate and an 80% to 87% overall response rate.

• #36 Treatment for Hairy Cell Leukemia | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/leukemias/treatment/treatment-hairy-cell-leukemia

  Our team members have expertise and access to all current treatments approved by the US Food and Drug Administration. The most common approved treatment for HCL is an anticancer medication called cladribine (Leustatin). Most people who receive initial treatment with a single cycle of cladribine have a good response. […] For those who respond to cladribine initially but need further treatment for HCL years later, cladribine may bring about a second response. […] Another standard anticancer medication sometimes used to treat HCL is called pentostatin (Nipent). […] Cancer-targeted antibody therapy is another approved form of anticancer therapy sometimes used to treat HCL. One example is rituximab (Rituxan). Rituximab may be used by itself or with other chemotherapy drugs, such as cladribine.

• #37 Treatment for Hairy Cell Leukemia | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/leukemias/treatment/treatment-hairy-cell-leukemia

  In very rare cases of HCL, removing the spleen (splenectomy) may be considered. […] Researchers conduct clinical trials to find new therapies for HCL. Trials are available for people who have had prior treatment for HCL as well as those whove never been treated. […] MSK is leading a clinical trial investigating a chemotherapy-free drug combination for people with HCL who are receiving treatment for the first time. […] Enrollment in the trial is ongoing. […] Among the therapies tested at MSK is a targeted therapy called vemurafenib (Zelboraf). Vemurafenib is an oral drug that can bring about remission (when no trace of cancer is detectable) or slow the growth of HCL in people with a BRAF mutation. […] We are also studying other therapies for HCL that has been resistant to or has come back after standard treatments. These include moxetumomab pasudotox (Lumoxiti) and ibrutinib (Imbruvica). Moxetumomab pasudotox is an anticancer medication that targets HCL cells. It delivers a drug that helps kill the leukemia cells.

• #38 Leukemia: Nursing Diagnoses, Care Plans, Assessment & Interventions | NurseTogether

  https://www.nursetogether.com/leukemia-nursing-diagnosis-care-plan/

  Leukemia can cause an overwhelming sense of exhaustion or fatigue which affects the patient mentally and physically. Like other blood cancers, leukemia can directly cause anemia which prevents the bone marrow from producing healthy and normal blood cells to support oxygenation. […] Patients with leukemia are at risk for imbalanced fluid volume caused by symptoms of the disease and/or treatments. […] Patients with leukemia are at risk for developing infections as they have a low white blood cell count and a compromised immune system. In addition, cancer treatments like chemotherapy can destroy both cancer and healthy infection-fighting white blood cells.

• #39 Hairy Cell Leukemia: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/23177-hairy-cell-leukemia

  Chemotherapy is the most common initial (first-line) treatment for people who have symptoms with hairy cell leukemia. Cladribine (Leustatin) or pentostatin (Nipent) are common initial anticancer drug treatments for this condition. […] All cancer treatments have side effects. In this case, the chemotherapy drugs that treat hairy cell leukemia increase your risk of infections that may be life-threatening. Your oncologist will explain what steps you can take to prevent infections. Theyll also tell you what changes in your body may be signs you have an infection. […] Hairy cell leukemia increases the chance youll develop infections that can be life-threatening. You can strengthen your immune system and protect yourself from infection. Here are some suggestions: Fill your plate with healthy foods: Fruits, veggies, lean sources of protein and whole grains are just some examples of foods that bolster immune function. Build activity into your daily routine: Daily activity helps many aspects of your health, including your immune system. Catch enough ZZZs: Not getting enough sleep can prevent your immune system from working as it should. Stay up-to-date on vaccines: Vaccines train your body to fight off germs that can make you sick. Talk to your provider about which vaccines you need and when.

• #40 Hairy Cell Leukemia: Early Detection for Better Health Outcomes – Life Imaging FLA

  https://www.lifeimagingfla.com/hairy-cell-leukemia-detecting-early-stages/

  Good nutrition can support overall health and help manage symptoms of Hairy Cell Leukemia. Focusing on a balanced diet can make a difference in the treatment journey. […] Physical activity can help manage symptoms and improve overall health for HCL patients. Tailoring exercise routines to individual capabilities and needs is key. […] By understanding the symptoms, risks, and early detection methods of Hairy Cell Leukemia, patients can take proactive steps toward effective treatment. Regular screenings, personalized treatment plans, and strong support systems play crucial roles in managing this chronic illness and improving quality of life. […] Hairy Cell Leukemia, a rare but treatable form of blood cancer, requires vigilant monitoring and early detection for the best outcomes. From understanding symptoms and risk factors to exploring advanced treatment options, being informed can make a significant difference in managing HCL. Regular screenings, personalized treatments, genetic testing, and supportive care are vital components in effectively combating this disease.

• #41 Leukemia: Nursing Diagnoses, Care Plans, Assessment & Interventions | NurseTogether

  https://www.nursetogether.com/leukemia-nursing-diagnosis-care-plan/

  Leukemia is a progressive condition and can be fatal if left untreated. While there is no cure for leukemia, attaining remission is a realistic option for some patients. Nurses support patients with leukemia by providing supportive care, especially for those who are undergoing chemotherapy, radiation, and other biologic therapies. It is essential to manage and prevent complications, provide comfort measures, patient and family education, and continuous emotional support. […] Nursing interventions and care are essential for the patients recovery. In the following section, you will learn more about possible nursing interventions for a patient with leukemia. […] Nursing care plans help prioritize assessments and interventions for both short and long-term goals of care. […] Bone pain is common in patients diagnosed with leukemia. Pain occurs when the bone marrow expands from the accumulation of abnormal white blood cells. This is commonly felt in the arms and legs. Chemotherapy also causes neuropathic pain described as tingling, numbness, and shooting sensation in the hands and feet.

• #42 8 Leukemia Nursing Care Plans – Nurseslabs

  https://nurseslabs.com/leukemia-nursing-care-plans/

  Clients with leukemia are at risk for deficient fluid volume due to several factors, including excessive losses through vomiting, diarrhea, or bleeding, decreased fluid intake due to poor appetite, and increased fluid needs resulting from fever or chemotherapy. […] Effective pain management is essential to alleviate suffering, enhance quality of life, and promote patient comfort. Nursing interventions play a pivotal role in managing acute pain in these patients. […] Health teachings and patient education empower individuals to make informed decisions, manage treatment-related symptoms, and adopt healthy lifestyle practices. […] Through vigilant assessment and monitoring, nurses play a critical role in identifying signs of infection, bleeding, organ dysfunction, and other potential complications.

• #43 Leukemia: Nursing Diagnoses, Care Plans, Assessment & Interventions | NurseTogether

  https://www.nursetogether.com/leukemia-nursing-diagnosis-care-plan/

  Leukemia can cause an overwhelming sense of exhaustion or fatigue which affects the patient mentally and physically. Like other blood cancers, leukemia can directly cause anemia which prevents the bone marrow from producing healthy and normal blood cells to support oxygenation. […] Patients with leukemia are at risk for imbalanced fluid volume caused by symptoms of the disease and/or treatments. […] Patients with leukemia are at risk for developing infections as they have a low white blood cell count and a compromised immune system. In addition, cancer treatments like chemotherapy can destroy both cancer and healthy infection-fighting white blood cells.

• #44 8 Leukemia Nursing Care Plans – Nurseslabs

  https://nurseslabs.com/leukemia-nursing-care-plans/

  Clients with leukemia are at risk for deficient fluid volume due to several factors, including excessive losses through vomiting, diarrhea, or bleeding, decreased fluid intake due to poor appetite, and increased fluid needs resulting from fever or chemotherapy. […] Effective pain management is essential to alleviate suffering, enhance quality of life, and promote patient comfort. Nursing interventions play a pivotal role in managing acute pain in these patients. […] Health teachings and patient education empower individuals to make informed decisions, manage treatment-related symptoms, and adopt healthy lifestyle practices. […] Through vigilant assessment and monitoring, nurses play a critical role in identifying signs of infection, bleeding, organ dysfunction, and other potential complications.

• #45 8 Leukemia Nursing Care Plans – Nurseslabs

  https://nurseslabs.com/leukemia-nursing-care-plans/

  Clients with leukemia are at risk for deficient fluid volume due to several factors, including excessive losses through vomiting, diarrhea, or bleeding, decreased fluid intake due to poor appetite, and increased fluid needs resulting from fever or chemotherapy. […] Effective pain management is essential to alleviate suffering, enhance quality of life, and promote patient comfort. Nursing interventions play a pivotal role in managing acute pain in these patients. […] Health teachings and patient education empower individuals to make informed decisions, manage treatment-related symptoms, and adopt healthy lifestyle practices. […] Through vigilant assessment and monitoring, nurses play a critical role in identifying signs of infection, bleeding, organ dysfunction, and other potential complications.

• #46 Hairy Cell Leukemia: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/23177-hairy-cell-leukemia

  Chemotherapy is the most common initial (first-line) treatment for people who have symptoms with hairy cell leukemia. Cladribine (Leustatin) or pentostatin (Nipent) are common initial anticancer drug treatments for this condition. […] All cancer treatments have side effects. In this case, the chemotherapy drugs that treat hairy cell leukemia increase your risk of infections that may be life-threatening. Your oncologist will explain what steps you can take to prevent infections. Theyll also tell you what changes in your body may be signs you have an infection. […] Hairy cell leukemia increases the chance youll develop infections that can be life-threatening. You can strengthen your immune system and protect yourself from infection. Here are some suggestions: Fill your plate with healthy foods: Fruits, veggies, lean sources of protein and whole grains are just some examples of foods that bolster immune function. Build activity into your daily routine: Daily activity helps many aspects of your health, including your immune system. Catch enough ZZZs: Not getting enough sleep can prevent your immune system from working as it should. Stay up-to-date on vaccines: Vaccines train your body to fight off germs that can make you sick. Talk to your provider about which vaccines you need and when.

• #47 Hairy cell leukemia | Altru Health System

  https://www.altru.org/health-library/conditions/hairy-cell-leukemia

  Your health care provider will have your cancer cells tested to see whether targeted drug therapy is likely to work for you. […] No alternative medicines are helpful for treating hairy cell leukemia. Alternative medicine might be helpful in other ways. It may help you cope with the stress of a cancer diagnosis and the treatment side effects. […] A cancer diagnosis can feel overwhelming. To help you cope, you might consider trying to: Find out enough to feel comfortable making decisions about your care. Learn about hairy cell leukemia and cancer treatments. This can help you feel more confident about making decisions about your treatment. […] Ask your health care provider to suggest some reliable sources of information to get you started. […] Connect with other cancer survivors. Friends and family provide an important support network during your cancer experience. But they can’t always understand what it’s like to face cancer. Other cancer survivors provide a unique network of support.

• #48 Hairy cell leukemia | Health Library | Memorial Health System

  https://www.mhsystem.org/health-library/con-20372939/

  Your health care provider will have your cancer cells tested to see whether targeted drug therapy is likely to work for you. […] No alternative medicines are helpful for treating hairy cell leukemia. Alternative medicine might be helpful in other ways. It may help you cope with the stress of a cancer diagnosis and the treatment side effects. […] Talk to your health care provider about your options, such as: Art therapy, Exercise, Meditation, Music therapy, Relaxation exercises, Spirituality. […] A cancer diagnosis can feel overwhelming. To help you cope, you might consider trying to: Find out enough to feel comfortable making decisions about your care. Learn about hairy cell leukemia and cancer treatments. This can help you feel more confident about making decisions about your treatment.

• #49 Hairy Cell Leukemia: Early Detection for Better Health Outcomes – Life Imaging FLA

  https://www.lifeimagingfla.com/hairy-cell-leukemia-detecting-early-stages/

  Good nutrition can support overall health and help manage symptoms of Hairy Cell Leukemia. Focusing on a balanced diet can make a difference in the treatment journey. […] Physical activity can help manage symptoms and improve overall health for HCL patients. Tailoring exercise routines to individual capabilities and needs is key. […] By understanding the symptoms, risks, and early detection methods of Hairy Cell Leukemia, patients can take proactive steps toward effective treatment. Regular screenings, personalized treatment plans, and strong support systems play crucial roles in managing this chronic illness and improving quality of life. […] Hairy Cell Leukemia, a rare but treatable form of blood cancer, requires vigilant monitoring and early detection for the best outcomes. From understanding symptoms and risk factors to exploring advanced treatment options, being informed can make a significant difference in managing HCL. Regular screenings, personalized treatments, genetic testing, and supportive care are vital components in effectively combating this disease.

• #50 Hairy Cell Leukemia: Early Detection for Better Health Outcomes – Life Imaging FLA

  https://www.lifeimagingfla.com/hairy-cell-leukemia-detecting-early-stages/

  After an initial diagnosis, regular monitoring and follow-up are essential. This helps track the diseases progression and the effectiveness of treatment. Routine blood tests, bone marrow exams, and imaging tests ensure the disease is managed effectively. […] Making certain lifestyle changes can help patients manage symptoms and support their overall health during and after treatment. […] Having a strong support system is important for managing Hairy Cell Leukemia. Various resources are available to help patients and their families. […] Patient advocacy is important in the fight against Hairy Cell Leukemia. Advocates work to raise awareness, support research, and improve patient care. […] Living with Hairy Cell Leukemia can affect a persons mental and emotional well-being. Addressing the psychological impact is an important part of comprehensive care.

• #51 Hairy cell leukemia | Altru Health System

  https://www.altru.org/health-library/conditions/hairy-cell-leukemia

  Ask your provider about support groups or organizations in your community that can connect you with other cancer survivors. Organizations such as the Hairy Cell Leukemia Foundation and the Leukemia Lymphoma Society offer ways to connect with others online. […] Take care of yourself. You can’t control whether your hairy cell leukemia comes back, but you can control other aspects of your health. […] Take care of yourself by eating a balanced diet with plenty of fruits and vegetables. Exercise regularly. Get enough sleep so that you wake up feeling refreshed. Find healthy ways to cope with the stresses in your life.

• #52 Hairy cell leukemia | Health Library | Memorial Health System

  https://www.mhsystem.org/health-library/con-20372939/

  Ask your health care provider to suggest some reliable sources of information to get you started. […] Connect with other cancer survivors. Friends and family provide an important support network during your cancer experience. But they cant always understand what its like to face cancer. Other cancer survivors provide a unique network of support. […] Ask your provider about support groups or organizations in your community that can connect you with other cancer survivors. Organizations such as the Hairy Cell Leukemia Foundation and the Leukemia Lymphoma Society offer ways to connect with others online. […] Take care of yourself. You cant control whether your hairy cell leukemia comes back, but you can control other aspects of your health. […] Take care of yourself by eating a balanced diet with plenty of fruits and vegetables. Exercise regularly. Get enough sleep so that you wake up feeling refreshed. Find healthy ways to cope with the stresses in your life.

• #53 Hairy Cell Leukemia – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK499845/

  Once treated, these patients need to be followed by the oncology nurse and primary care physician with regular monitoring of blood work. […] The interprofessional team can optimize the treatment of these patients through communication and coordination of care. Oncologists provide diagnoses and care plans. Nurse practitioners implement care and monitor treatment. Specialty care oncologic nurses should work with the team for coordination of care and are involved in patient education. […] Supportive care measures such as antimicrobial prophylaxis for viral and pneumocystis pneumonia should be considered for those with significant cytopenias. Patients should be educated about personal hygiene and the importance of handwashing.

• #54 Leukemia: Definition, Types & Risk Factors | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/leukemia.html

  Whether you are treated as an inpatient or outpatient, our comprehensive program offers all the services needed to care for leukemia and respond to its impact on your body. We aim to accomplish as much care as possible on an outpatient basis. If hospitalization is needed, our expert staff is specially trained to care for patients at every phase of the treatment journey.

• #55 Hairy cell leukaemia | Lymphoma Action

  https://lymphoma-action.org.uk/types-lymphoma/hairy-cell-leukaemia

  When your hairy cell leukaemia is in remission after treatment, you have regular follow-up appointments. These might be at your hospital or at your local GP surgery. They are usually every 3 to 12 months. […] If you experience a relapse more than 2 years after your first treatment, you are likely to have the same treatment as you had before. This may be combined with an antibody therapy called rituximab. If you experience a relapse less than 2 years after your first treatment, your medical team might recommend: a different chemotherapy drug, usually combined with rituximab; a different targeted drug as part of a clinical trial.

• #56 Hairy cell leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/chronic-lymphocytic-leukemia-cll/treatment/hairy-cell-leukemia

  HCL and its treatments can cause certain problems, including infection, bleeding and low blood cell counts. If you develop these problems, you may be given antibiotics to prevent and treat infections. […] Follow-up care lets your healthcare team keep track of your health for a period of time after treatment ends. This important part of cancer care is often shared among the cancer specialists and your family doctor.

• #57 Hairy Cell Leukemia: Symptoms, Causes, Treatments

  https://resources.healthgrades.com/right-care/leukemia/hairy-cell-leukemia

  There are side effects with anticancer drugs, particularly with cladribine and pentostatin. These drugs can suppress the immune system for long periods, which makes you vulnerable to infection and reduces your ability to develop immunity upon vaccination. […] Talk with your doctor about the most appropriate treatment for your condition and what to expect with side effects, including what precautions to take to reduce your chance of complications. […] People with hairy cell leukemia should have long-term follow-up care to help detect any secondary cancers that develop.

• #58 Hairy cell leukemia – Symptoms, diagnosis and treatment | BMJ Best Practice US

  https://bestpractice.bmj.com/topics/en-us/890?locale=th&

  Hairy cell leukemia (HCL) is an uncommon, indolent, mature B-cell neoplasm. It is characterized by symptoms of fatigue, a markedly enlarged spleen, pancytopenia, and a distinctive histologic appearance on peripheral blood smear and bone marrow biopsy. […] HCL is not curable. However, it is highly responsive to therapy; median relapse-free survival of a decade or more has been reported. […] In symptomatic patients or those with worsening blood counts, treatment with purine analogs is recommended. […] Supportive care with antibiotics, anti-infective prophylaxis, granulocyte colony-stimulating factor, and irradiated blood products may be required as part of treatment.

• #59 Leukemia: Nursing Diagnoses, Care Plans, Assessment & Interventions | NurseTogether

  https://www.nursetogether.com/leukemia-nursing-diagnosis-care-plan/

  Leukemia is a progressive condition and can be fatal if left untreated. While there is no cure for leukemia, attaining remission is a realistic option for some patients. Nurses support patients with leukemia by providing supportive care, especially for those who are undergoing chemotherapy, radiation, and other biologic therapies. It is essential to manage and prevent complications, provide comfort measures, patient and family education, and continuous emotional support. […] Nursing interventions and care are essential for the patients recovery. In the following section, you will learn more about possible nursing interventions for a patient with leukemia. […] Nursing care plans help prioritize assessments and interventions for both short and long-term goals of care. […] Bone pain is common in patients diagnosed with leukemia. Pain occurs when the bone marrow expands from the accumulation of abnormal white blood cells. This is commonly felt in the arms and legs. Chemotherapy also causes neuropathic pain described as tingling, numbness, and shooting sensation in the hands and feet.

• #60 Addressing the Unmet Needs of Patients with Hairy Cell Leukemia

  https://www.oncnursingnews.com/view/addressing-the-unmet-needs-of-patients-with-hairy-cell-leukemia

  For patients with hairy cell leukemia, it’s complications after treatment that can be life-threatening. […] So hairy cell leukemia, in many cases, doesn’t shorten people’s natural lifespans, but the few things that do affect hairy cell leukemia patients greatly are actually infection, which is very high on the list. […] I think looking at therapies for patients with uncontrolled active or opportunistic infections, and better supportive care and management, surrounding it is really important.

• #61 Hairy Cell Leukemia – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK499845/

  Hairy cell leukemia (HCL) is a rare, chronic B-cell malignancy that involves the spleen, bone marrow, and peripheral blood. This activity reviews the evaluation and management of hairy cell leukemia and explains the role of the interprofessional team in improving care for patients with this condition. […] Describe the importance of improving care coordination among the interprofessional team members to enhance the delivery of care for patients affected by hairy cell leukemia. […] Given its incurable nature, hairy cell leukemia treatment is reserved for symptomatic patients, including significant fatigue, symptomatic splenomegaly, and significant cytopenias (hemoglobin less than 12 g/dL, platelets, 100000/mcL, ANC less than 1000/mcL). Asymptomatic individuals should be monitored closely for disease progression with history and physical and CBC approximately every 3 to 6 months.

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