Zgaga
Etiologia i przyczyny
Zgaga (heartburn) jest wynikiem refluksu kwasu żołądkowego do przełyku, spowodowanego dysfunkcją dolnego zwieracza przełyku (LES). LES, który normalnie zapobiega cofaniu się treści żołądkowej, może być osłabiony przez czynniki anatomiczne (np. przepuklina rozworu przełykowego), fizjologiczne (ciąża, palenie tytoniu), dietetyczne (spożycie czekolady, kawy, alkoholu, tłustych i pikantnych potraw) oraz farmakologiczne (benzodiazepiny, blokery kanału wapniowego, NLPZ). Refluks jest nasilany przez pozycję leżącą i zwiększone ciśnienie w jamie brzusznej, co prowadzi do podrażnienia wrażliwej wyściółki przełyku. Sporadyczna zgaga różni się od przewlekłej choroby refluksowej przełyku (GERD), która wymaga regularnych interwencji i może prowadzić do powikłań takich jak zapalenie przełyku, owrzodzenia, zwężenia oraz przełyk Barretta, zwiększający ryzyko raka przełyku.
- Zgaga – Etiologia, przyczyny, czynniki wywołujące
- Mechanizm powstawania zgagi
- Anatomiczne przyczyny zgagi
- Fizjologiczne przyczyny zgagi
- Dieta i styl życia jako przyczyny zgagi
- Farmakologiczne przyczyny zgagi
- Refluks przejściowy a choroba refluksowa przełyku
- Czynniki ryzyka rozwoju zgagi
- Nietypowe przyczyny zgagi
- Podsumowanie przyczyn zgagi
Zgaga – Etiologia, przyczyny, czynniki wywołujące
Zgaga (ang. heartburn) to palący ból odczuwany za mostkiem lub w górnej części brzucha, który często przemieszcza się w górę w kierunku gardła. Uczucie to jest spowodowane cofaniem się kwasu żołądkowego do przełyku (refluks), co prowadzi do podrażnienia jego wrażliwej wyściółki.12 Zrozumienie przyczyn zgagi jest kluczowe dla skutecznego zarządzania tym powszechnym problemem zdrowotnym i jego leczenia.
Mechanizm powstawania zgagi
Główną przyczyną zgagi jest nieprawidłowe działanie dolnego zwieracza przełyku (ang. Lower Esophageal Sphincter, LES). Ten mięśniowy zawór znajduje się na granicy przełyku i żołądka i w normalnych warunkach otwiera się, aby umożliwić przejście pokarmu do żołądka, a następnie zamyka się, zapobiegając cofaniu się treści żołądkowej.12 Gdy dolny zwieracz przełyku rozluźnia się w niewłaściwym momencie, jest osłabiony lub nie zamyka się prawidłowo, kwas żołądkowy może cofać się do przełyku, powodując typowe uczucie pieczenia.12
Refluks kwasu żołądkowego do przełyku jest szczególnie odczuwalny podczas leżenia lub pochylania się, ponieważ w tych pozycjach grawitacja nie pomaga utrzymać kwasu w żołądku.1 Ponadto, wyściółka przełyku, w przeciwieństwie do wyściółki żołądka, nie jest przystosowana do kontaktu z kwasem żołądkowym, co powoduje podrażnienie i ból.1
Anatomiczne przyczyny zgagi
Istnieje kilka anatomicznych czynników, które mogą przyczyniać się do osłabienia dolnego zwieracza przełyku i powstawania zgagi:
- Przepuklina rozworu przełykowego (przepuklina rozworu przełykowego przepony) – występuje, gdy górna część żołądka przemieszcza się przez przeponę do klatki piersiowej. Jest to jedna z najczęstszych przyczyn zgagi, ponieważ osłabia dolny zwieracz przełyku i ułatwia cofanie się kwasu.123
- Otyłość – zwiększa ciśnienie w jamie brzusznej, co może wypychać zawartość żołądka w górę i osłabiać dolny zwieracz przełyku. Nadmierna masa ciała ma podobny wpływ na LES jak ciąża.12
- Wady wrodzone – niektóre wrodzone defekty, takie jak zarośnięcie przełyku i przepukliny, mogą wpływać na prawidłowe funkcjonowanie LES.1
- Choroby tkanki łącznej – schorzenia takie jak twardzina układowa mogą wpływać na mięśnie przełyku.12
- Wcześniejsze operacje – zabiegi chirurgiczne w obrębie klatki piersiowej lub górnej części brzucha mogą uszkodzić przełyk.1
Fizjologiczne przyczyny zgagi
Czynniki fizjologiczne również odgrywają istotną rolę w rozwoju zgagi:
- Ciąża – jest częstą przyczyną przejściowej zgagi. Zwiększone ciśnienie i objętość w jamie brzusznej mogą wypychać, rozciągać i osłabiać mięśnie przepony, które podtrzymują dolny zwieracz przełyku. Dodatkowo hormony ciążowe, szczególnie progesteron, mogą powodować rozluźnienie LES.123
- Palenie tytoniu – dym tytoniowy rozluźnia dolny zwieracz przełyku, niezależnie od tego, czy jest się aktywnym palaczem, czy narażonym na bierne wdychanie dymu. Palenie wywołuje również kaszel, który otwiera LES. Długotrwałe palenie i przewlekły kaszel mogą osłabiać mięśnie przepony i przyczyniać się do rozwoju przepukliny rozworu przełykowego.12
- Stres i lęk – mogą zwiększać wydzielanie kwasu żołądkowego i prowadzić do napięcia mięśni wokół żołądka, co sprzyja cofaniu się kwasu do przełyku.12
- Infekcja Helicobacter pylori – ten rodzaj bakterii, żyjący w żołądku, może podrażniać wyściółkę żołądka, powodując zgagę, refluks i owrzodzenia.12
Dieta i styl życia jako przyczyny zgagi
Pewne nawyki żywieniowe i elementy stylu życia mogą znacząco zwiększać ryzyko wystąpienia zgagi:
- Pokarmy i napoje – niektóre produkty spożywcze mogą rozluźniać dolny zwieracz przełyku lub zwiększać wydzielanie kwasu żołądkowego, co prowadzi do zgagi. Należą do nich:
- Czekolada, kawa, alkohol, mięta, czosnek i cebula – mogą mieć efekt rozluźniający na LES.12
- Tłuste pokarmy – zwiększają wydzielanie kwasu żołądkowego i dłużej się trawią, co stwarza więcej okazji do cofania się kwasu.12
- Pikantne potrawy, cytrusy, pomidory – mogą bezpośrednio podrażniać wyściółkę przełyku.12
- Napoje gazowane i kofeinowe – mogą zwiększać wydzielanie kwasu.12
- Nawyki żywieniowe:
- Ćwiczenia – intensywne ćwiczenia, szczególnie te, które zwiększają ciśnienie w jamie brzusznej, jak podnoszenie ciężarów czy brzuszki, mogą zwiększać ryzyko refluksu.12
- Odzież – ciasna odzież, szczególnie wokół talii, może zwiększać ciśnienie na żołądek i powodować cofanie się kwasu.12
Farmakologiczne przyczyny zgagi
Liczne leki mogą powodować lub nasilać zgagę, w tym:
- Benzodiazepiny – rodzaj leków uspokajających.12
- Blokery kanału wapniowego – stosowane w leczeniu nadciśnienia tętniczego.12
- Trójpierścieniowe leki przeciwdepresyjne – stosowane w leczeniu depresji i bólu.12
- Niesteroidowe leki przeciwzapalne (NLPZ) – takie jak aspiryna i ibuprofen.12
- Teofilina – popularny lek stosowany w astmie.12
- Leki hormonalne – stosowane w terapii menopauzy.1
- Bisfosfoniany – stosowane w leczeniu osteoporozy.12
- Preparaty potasu i żelaza – suplementy diety.12
Refluks przejściowy a choroba refluksowa przełyku
Warto zaznaczyć różnicę między sporadyczną zgagą a przewlekłą chorobą refluksową przełyku (GERD):
- Sporadyczna zgaga – występuje okazjonalnie, zwykle po spożyciu określonych pokarmów lub w specyficznych sytuacjach.12
- Choroba refluksowa przełyku (GERD) – diagnozowana jest, gdy refluks i zgaga występują regularnie (co najmniej dwa razy w tygodniu) przez dłuższy czas, powodując chroniczne podrażnienie przełyku.12
Nieleczona GERD może prowadzić do poważnych powikłań, takich jak zapalenie przełyku, owrzodzenia, zwężenie przełyku i przełyk Barretta (stan przedrakowy, który zwiększa ryzyko raka przełyku).123
Czynniki ryzyka rozwoju zgagi
Oprócz wymienionych przyczyn, istnieją również czynniki, które zwiększają ryzyko wystąpienia zgagi:
- Wiek – proces starzenia się może powodować osłabienie mięśni dolnego zwieracza przełyku.12
- Genetyka – badania bliźniąt i rodzin sugerują, że około 30-40% przypadków refluksu jest prawdopodobnie dziedziczna, być może z powodu dziedziczonych problemów mięśniowych lub strukturalnych w żołądku lub przełyku.1
- Choroby współistniejące – schorzenia takie jak cukrzyca, zaburzenia opróżniania żołądka, choroby autoimmunologiczne (zespół CREST, objaw Raynauda) mogą zwiększać ryzyko wystąpienia zgagi.12
- Reakcje na pokarmy – nietolerancje pokarmowe, takie jak nietolerancja laktozy lub glutenu, mogą przyczyniać się do zgagi.1
Nietypowe przyczyny zgagi
Warto wspomnieć również o mniej oczywistych przyczynach objawów podobnych do zgagi:
- Refluks niekwaśny – w niektórych przypadkach zgaga może być spowodowana przez cofanie się innych składników treści żołądkowej, takich jak żółć lub enzymy trzustkowe, a nie tylko kwas żołądkowy.12
- Nadwrażliwość przełyku – niektóre osoby mogą mieć przełyk niezwykle wrażliwy na bodźce, które normalnie nie wywołują bólu, co określa się jako czynnościową zgagę.12
- Zapalenie przełyku – może być spowodowane przez wirusy lub inne zarazki, leki lub częste wymioty, a nie tylko przez refluks kwasu.12
Podsumowanie przyczyn zgagi
Zgaga to złożony objaw, który może wynikać z wielu różnych przyczyn. Najczęstszym mechanizmem jest osłabienie lub nieprawidłowe funkcjonowanie dolnego zwieracza przełyku, co prowadzi do cofania się kwasu żołądkowego do przełyku. Czynniki anatomiczne, fizjologiczne, dietetyczne, związane ze stylem życia oraz farmakologiczne mogą przyczyniać się do rozwoju tego problemu.12
Zrozumienie specyficznych przyczyn zgagi u danej osoby jest kluczowe dla skutecznego leczenia. W przypadku sporadycznej zgagi wystarczające mogą być zmiany stylu życia i diety, natomiast w przewlekłej chorobie refluksowej przełyku (GERD) konieczne może być długotrwałe leczenie farmakologiczne lub nawet interwencja chirurgiczna, aby zapobiec poważnym powikłaniom.12
Warto pamiętać, że przewlekła zgaga nie powinna być ignorowana, gdyż może prowadzić do poważnych problemów zdrowotnych, w tym do przełyku Barretta, który zwiększa ryzyko rozwoju raka przełyku.12
Kolejne rozdziały
Zapraszamy do dalszego czytania naszego leksykonu.
Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.
Materiały źródłowe
- #1 Heartburn – Symptoms & causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/heartburn/symptoms-causes/syc-20373223
Heartburn occurs when stomach acid backs up into the tube that carries food from your mouth to your stomach (esophagus). […] If the lower esophageal sphincter isn’t working as it should, stomach acid can flow back up into the esophagus (acid reflux) and cause heartburn. The acid backup may be worse when you’re bent over or lying down. […] Acid reflux occurs when the sphincter muscle at the lower end of your esophagus relaxes at the wrong time, allowing stomach acid to back up into your esophagus. This can cause heartburn and other signs and symptoms. Frequent or constant reflux can lead to .
- #1 Gastroesophageal reflux disease (GERD) – Symptoms and causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/gerd/symptoms-causes/syc-20361940
Acid reflux happens when the sphincter muscle at the lower end of the esophagus relaxes at the wrong time, allowing stomach acid to back up into the esophagus. This can cause heartburn and other symptoms. Frequent or constant reflux can lead to GERD. […] GERD is caused by frequent acid reflux or reflux of nonacidic content from the stomach. […] If the sphincter does not relax as is typical or it weakens, stomach acid can flow back into the esophagus. This constant backwash of acid irritates the lining of the esophagus, often causing it to become inflamed.
- #1 Heartburn: Burn becomes a burden – Mayo Clinic Health Systemhttps://www.mayoclinichealthsystem.org/hometown-health/speaking-of-health/heartburn-burn-becomes-a-burden
The lining of the esophagus is sensitive to acid because is not protected like the lining in the stomach. Typically, people who experience heartburn are affected when the acid from the stomach goes where it should not be or is not cleared from the food pipe in a timely manner. […] Symptoms also can develop if the protective mechanism of the lining of the gut is weakened, which may happen from use of over-the-counter medications such as nonsteroidal anti-inflammatory drugs like aspirin or ibuprofen. […] If heartburn and acid reflux happen more two or more times per week, and it interferes with daily activities, it is typically considered to be gastroesophageal reflux disease, or GERD.
- #1 Heartburn: MedlinePlus Medical EncyclopediaLockhttps://medlineplus.gov/ency/article/003114.htm
Heartburn is a painful burning feeling just below or behind the breastbone. Most of the time, it comes from the esophagus. The pain often rises in your chest from your stomach. It may also spread to your neck or throat. […] Almost everyone has heartburn at some time. If you have heartburn very often, you may have gastroesophageal reflux disease (GERD). […] Normally when food or liquid enters your stomach, a band of muscle at the lower end of your esophagus closes off the esophagus. This band is called the lower esophageal sphincter (LES). If this band does not close tightly enough, food or stomach acid can back up (reflux) into the esophagus. The stomach contents can irritate the esophagus and cause heartburn and other symptoms. […] Heartburn is more likely if you have a hiatal hernia. A hiatal hernia is a condition which occurs when the top part of the stomach pokes into the chest cavity. This weakens the LES so that it is easier for acid to back up from the stomach into the esophagus. […] Pregnancy and many medicines can bring on heartburn or make it worse. […] Talk to your health care provider if you think one of your medicines may be causing heartburn. Never change or stop taking medicine without talking to your provider first.
- #1 Acid Reflux & GERD: Symptoms, What It Is, Causes, Treatmenthttps://my.clevelandclinic.org/health/diseases/17019-acid-reflux-gerd
Pregnancy is a common cause of temporary acid reflux. The pressure and volume in your abdomen can push, stretch and weaken the muscles in your diaphragm that support your LES. Pregnancy hormones may also encourage your LES to relax. […] Obesity increases the pressure and volume in your abdomen, which affects your LES similarly to how pregnancy does. Obesity also tends to last longer than pregnancy, which can weaken the muscles more permanently. […] Smoking. Tobacco smoke relaxes your LES, whether you’re the one smoking or you’re exposed to second-hand smoke. Smoking also triggers coughing, which opens your LES. Smoking and chronic coughing can weaken your diaphragm muscles and contribute to developing a hiatal hernia. […] Other possible causes of GERD include: Birth defects. Congenital defects like esophageal atresia and hernias can affect your LES.
- #1 Acid Reflux & GERD: Symptoms, What It Is, Causes, Treatmenthttps://my.clevelandclinic.org/health/diseases/17019-acid-reflux-gerd
Connective tissue diseases. Diseases like scleroderma may affect your esophagus muscles. […] Prior surgery. Surgery in your chest or upper abdomen may have injured your esophagus. […] Medications. Certain medications can have a relaxing effect on your LES, including: Benzodiazepines, a type of sedative. […] Calcium channel blockers, which treat high blood pressure. […] Tricyclic antidepressants, which treat depression and pain. […] NSAIDs (nonsteroidal anti-inflammatory drugs) like aspirin and ibuprofen. […] Theophylline, a common asthma medication. […] Hormone therapy (HT) medications for menopause. […] Foods and drinks probably aren’t enough to cause acid reflux alone, but they can contribute to it. Chocolate, coffee, alcohol, mint, garlic and onions may have a relaxing effect on your LES in higher doses. […] Fatty foods increase stomach acid and take longer to digest, so there’s more opportunity for acid to escape. If you have a heavier meal for dinner, it might not have time to digest before you lie down.
- #1 What Causes Heartburn? – CNM College of Naturopathic Medicinehttps://www.naturopathy-uk.com/news/news-cnm-blog/blog/2020/05/29/what-causes-heartburn/
Acidic and inflammatory foods which tend to increase stomach acid production and exacerbate symptoms. […] Pregnancy due to the surge in hormones and because a womans digestive organs are compressed to accommodate the growing baby. […] Stress increases stomach acid production and causes muscle tension around the stomach, triggering it to push more acid up towards the oesophagus. […] Smoking as it damages the stomach lining and increases acid production. […] Helicobacter pylori infection. This is a type of bacteria which lives in the stomach and can aggravate the stomach lining, causing heartburn, reflux and ulcers.
- #1 What really causes heartburn? | Logansport Memorial HospitalSearchSearchFacebookYouTubeBlogTwitterhttps://www.logansportmemorial.org/blog/what-really-causes-heartburn
Heartburn is the common name for the burning in your neck and chest caused when your body pushes digestive acid up from your stomach into your esophagus, also known as acid reflux. […] For some people, they only experience heartburn now and then, and the typical trigger is due to eating certain acidic, fatty, or spicy foods, eating late at night before going to bed, or having a big meal. […] Though getting heartburn infrequently usually isnât a cause for alarm, you can make small but significant dietary changes to help prevent future occurrences. […] To lessen your chance of experiencing heartburn after mealtimes, consider avoiding or limiting your consumption of aggravating foods, including: high-fat foods, spicy foods, alcohol, black pepper, garlic, raw onions, chocolate, citrus foods, tomatoes, caffeine, acidic fruit juices, carbonated beverages, peppermint, foods with the additive carrageenan, like non-dairy milk.
- #1 Beyond Food: Other Causes of Heartburn and GERDhttps://www.webmd.com/heartburn-gerd/causes-of-heartburn
Heartburn is that burning sensation in your chest or throat thats caused by acid rising up from your stomach. Its a common symptom of the condition called gastroesophageal reflux disease or GERD, which is also called acid reflux. […] But eliminating foods that cause heartburn problems may not be enough. Many other factors can also play a role in triggering heartburn and causing GERD. […] Overeating can trigger heartburn. […] Eating too rapidly can be a heartburn trigger. […] Smoking cigarettes is another potential cause of heartburn and GERD. […] When the LES and the upper part of the stomach move above the diaphragm you develop a hiatal hernia. The hernia makes acid reflux, which causes heartburn, more likely. […] Research suggests that being obese or overweight can be a trigger for heartburn and reflux disease. […] Common medications taken for other problems, including over-the-counter and prescription drugs, can increase the likelihood of heartburn. […] Exercise can trigger heartburn. Sometimes thats due to increased pressure on the abdomen, which can increase the risk of acid reflux.
- #1 Heartburn: Causes, Symptoms, and Treatmenthttps://www.webmd.com/heartburn-gerd/understanding-heartburn-basics
Heartburn symptoms can start when the lower esophageal sphincter (LES) valve at the bottom of your esophagus doesn’t close correctly. […] We don’t know what causes the LES valve to weaken, but it could be caused by eating big meals too often, if you’re overweight, or you have a hiatal hernia (a hernia in your upper stomach that pushes through your diaphragm). […] Certain foods can relax your LES or increase stomach acid, including: Tomatoes, Citrus fruits, Garlic and onions, Chocolate, Coffee or caffeinated products, Alcohol, Peppermint, Foods high in fats and oils. […] You’re also more likely to get heartburn if you: Eat right before bedtime, Smoke, vape, or use tobacco products, Wear tight-fitting clothing or belts, Lie down or bend over after eating, Are stressed out, Are pregnant, Take certain medications, including some antibiotics and nonsteroidal anti-inflammatory drugs (NSAIDs), Are constipated.
- #1 Constant Heartburn: Top 10 Causes & What to Do – Tua Saúdehttps://www.tuasaude.com/en/constant-heartburn/
In pregnant women, heartburn may be present from the beginning of pregnancy. It occurs due to the hormonal changes that are normal during pregnancy, as well as the growth and heaviness of the belly. […] A food intolerance is characterized by difficulty in digesting a certain type of food, such as lactose or gluten. […] Wearing uncomfortable and tight clothing can cause pressure on the stomach, causing acidic stomach content to rise into the esophagus. […] Poor eating habits, like frequently eating fatty foods, fried foods, spicy foods and sugary foods can also cause constant heartburn. […] Smoking can weaken the esophageal sphincter, which is found between the stomach and esophagus. […] Stress and anxiety can increase the release of hormones (like cortisol) that stimulate stomach acid production and lead to heartburn.
- #1 GERD & Heartburn in Kids: Signs, Causes, & Treatment | CHOChttps://choc.org/programs-services/gastroenterology/gerd/
Gastroesophageal reflux disease (GERD) in kids is usually caused by immaturity of the LES that results in weakness of the muscle. However, certain foods, medications, developmental disorders and underlying diseases can also cause GERD in children. […] Some foods seem to affect the muscle tone of the lower esophageal sphincter (LES), allowing it to stay open longer than normal. These include, but are not limited to: Chocolate, Carbonated drinks, High-fat foods. […] Other foods increase acid production in the stomach, resulting in heartburn when reflux occurs, including: Citrus foods, Tomatoes and tomato sauces, Spicy foods. […] Medications and dietary supplements that can irritate your childâs esophagus and lead to GERD include: Antibiotics, such as tetracycline and clindamycin, Bisphosphonates taken orally, such as alendronate (Fosamax), ibandronate (Boniva) and risedronate (Actonel, Atelvia), Iron supplements, Potassium supplements, Quinidine, Pain relievers, such as Ibuprofen, Advil, Motrin and Aspirin.
- #1 Heartburn: Causes, symptoms, and treatmentshttps://www.medicalnewstoday.com/articles/9151
Heartburn is a symptom of acid reflux, which is when some of the stomach contents travel back up into the esophagus or food pipe. […] Persistent acid reflux that happens more than twice per week is what experts call gastroesophageal reflux disease (GERD). […] People of all ages may develop GERD. Some of the most common causes include obesity and smoking. […] A person may prevent heartburn by avoiding acidic foods and drinks that contain caffeine. […] Changes to lifestyle and behavior can prevent or improve heartburn symptoms.
- #1 The Medical Minute: Getting to the heart of heartburn | Penn State Universityhttps://www.psu.edu/news/hershey/story/medical-minute-getting-heart-heartburn
One in five Americans suffers from gastroesophageal reflux disease (GERD), commonly known as acid reflux. Its a digestive disorder in which acid backs up from the stomach into the esophagus, often causing painful symptoms such as burning in the chest, abdominal pain, bloating and difficulty swallowing. […] The most common symptom of GERD is heartburn, which is caused by the backflow of stomach acid. […] Its basically anything that causes a weak valve between the esophagus and the stomach, whether thats a general weakness or a hiatal hernia. […] GERD can damage the lining of the esophagus, which can start out just as esophagitis, an inflammation of the esophagus, then cause the esophagus to narrow, called an esophageal stricture. GERD can also increase the risk for Barretts esophagus, which is a precancerous lesion, and esophageal cancer.
- #1 Causes of Sudden Heartburn and How to Treat Ithttps://www.verywellhealth.com/why-am-i-getting-heartburn-all-of-a-sudden-7963004
Heartburn is a symptom of acid reflux. This occurs when acids in your stomach flow back into your esophagus (feeding tube), causing inflammation and pain. Acid reflux usually occurs because the valve that separates the esophagus from the stomach, called the lower esophageal sphincter (LES), is not shutting properly. […] There are many reasons why this might occur: […] People can develop heartburn symptoms as a result of natural aging. Aging can weaken the muscles of the LES, impacting their ability to stop stomach acids from leaking back into the esophagus. The risk can increase as you get older. […] Heartburn is a hallmark of indigestion along with belching, bloating, nausea, gas, and a feeling of fullness in the abdomen. Most cases are triggered by what you eat and drink. […] If you’re suddenly experiencing heartburn, it could be due to medications you recently started. Some drugs can cause the laxity (loosening) of the LES, while others trigger the overproduction of stomach acids. Both can lead to reflux.
- #1 Gastroesophageal reflux disease and heartburn Information | Mount Sinai – New Yorkhttps://www.mountsinai.org/health-library/report/gastroesophageal-reflux-disease-and-heartburn
A hiatal hernia occurs when part of the stomach protrudes up into the chest through the sheet of muscle called the diaphragm. This may result from a weakening of the surrounding tissues and may be aggravated by obesity or smoking. […] About 30% to 40% of reflux is most likely hereditary, according to several twin and family studies. An inherited risk exists in many cases of GERD, possibly because of inherited muscular or structural problems in the stomach or esophagus. Genetic factors may play an especially strong role in susceptibility to Barrett esophagus, a precancerous condition caused by very severe GERD. […] Other disorders that may contribute to GERD include diabetes, any gastrointestinal disorder (including peptic ulcers), lymphomas, and other types of cancer.
- #1 Heartburn (GERD): Facts, Treatment, Causes, Symptoms & Preventionhttps://www.emedicinehealth.com/heartburn_faqs/article_em.htm
Heartburn is caused by stomach acid moving up into the esophagus. Heartburn is caused by stomach acid moving up into the esophagus. […] Heartburn occurs when the lower esophageal sphincter does not close all the way. […] Many different things loosen the lower esophageal sphincter. […] Certain foods and drinks loosen the lower esophageal sphincter. These include chocolate, peppermint, caffeine-containing beverages (such as coffee, tea, and soft drinks), fatty foods, and alcohol. […] Anything that increases the pressure on the stomach can force stomach acid backward and cause heartburn. Lifting, straining, coughing, tight clothing, obesity, and pregnancy can worsen heartburn. […] Certain medical conditions increase a person’s chance of suffering from heartburn. A hiatal hernia, diabetes, and many autoimmune diseases (CREST syndrome, Raynaud’s phenomenon, and scleroderma) are linked to heartburn.
- #1https://consensus.app/questions/causes-of-heartburn/
Heartburn is a common gastrointestinal symptom characterized by a burning sensation in the chest or upper abdomen. Understanding the causes of heartburn is crucial for effective management and treatment. This article synthesizes findings from multiple research studies to provide a comprehensive overview of the causes of heartburn. […] Acid reflux is a primary cause of heartburn, particularly in patients with gastroesophageal reflux disease (GERD). GERD encompasses a spectrum of conditions, including reflux esophagitis, Barrett’s esophagus, and nonerosive reflux disease (NERD). The regurgitation of gastric acid into the esophagus irritates the esophageal lining, leading to the characteristic burning sensation. […] Interestingly, not all heartburn is caused by acidic reflux. In patients with NERD, weakly acidic or non-acidic reflux can also trigger heartburn. This suggests that other components of the refluxate, such as bile or pancreatic juices, may play a significant role. Additionally, mechanisms like esophageal hypersensitivity and abnormal tissue resistance have been proposed to explain heartburn in the absence of visible esophageal damage.
- #1https://consensus.app/questions/causes-of-heartburn/
Functional heartburn is characterized by heartburn symptoms without evidence of acid reflux or esophageal damage. This condition is thought to result from esophageal hypersensitivity, where the esophagus becomes overly responsive to stimuli that would not normally cause pain. […] Heartburn is a multifactorial condition with various underlying causes, including acid reflux, non-acidic reflux, hormonal changes during pregnancy, dietary and lifestyle factors, and esophageal hypersensitivity. Understanding these diverse mechanisms is essential for developing effective treatment strategies and improving patient outcomes. Further research is needed to explore the complex pathogenesis of heartburn and to refine therapeutic approaches for different patient subgroups. […] Heartburn in pernicious anemia patients may result from bile reflux, despite the absence of gastric acid.
- #1 Constant Heartburn: Causes, Symptoms, and Treatmenthttps://www.verywellhealth.com/constant-heartburn-5215258
Heartburn occurs when stomach acid backs up into the esophagus, causing burning, irritation, or pain in the chest. […] Constant heartburn may indicate an underlying health issue that should be investigated. […] Gastroesophageal reflux disease (GERD) can cause constant heartburn that occurs more than twice a week over a period of several weeks. […] GERD is very common in the United States, affecting approximately 20% of the population. […] There are several gastrointestinal diseases that can cause constant or recurrent heartburn. […] Esophagitis is a broad term that refers to any inflammation of the esophagus. […] Esophagitis can be caused by many things, including viruses or other germs, medications, or frequent vomiting. […] Constant heartburn can be a symptom of an underlying condition, such as GERD, esophagitis, or other gastrointestinal disorders. […] Experiencing heartburn more than once a week over a period of several weeks may indicate an underlying condition.
- #1 What Causes Heartburn ? Checklist | TUMShttps://www.tums.com/about-heartburn/causes/heartburn-causes-checklist/
While most heartburn sufferers may recognize the symptoms of the condition, few are aware of how it starts. The root cause of heartburn stems from a weakened lower esophageal sphincter (LES), or when the LES relaxes abnormally. […] It’s true that your meals, habits, or even medication could be triggering your heartburn; but the fact is that heartburn is a real condition with biological causes. Here are some physical reasons you could be suffering from heartburn: Pregnancy, Acid Reflux, GERD or Acid Reflux Disease, Weak esophageal muscles, Stomach emptying muscles, Obesity, Anxiety or depression, Hiatal hernia, Peptic ulcer.
- #1 GERD (Gastroesophageal Reflux Disease) > Fact Sheets > Yale Medicinehttps://www.yalemedicine.org/conditions/gerd-gastroesophageal-reflux-disease
The most common symptom of GERD is heartburn, which may last for several hours. […] Most people with GERD only experience mild to moderate symptoms. But those who have more severe symptoms or those whose symptoms persist in spite of treatment are at risk of long-term damage to the esophagus. […] Several factors can increase the risk of developing GERD, including: Weight gain, being overweight or obese […] If your doctor suspects you have GERD after the initial exam, he or she may ask you to begin taking a medication. […] Treatment for GERD typically involves lifestyle modification, medications, and in rare cases, surgery. […] GERD can be treated effectively. Medications and lifestyle changes are usually helpful in controlling symptoms; however, because GERD tends to recur, long-term use of medications may be necessary.
- #1 When Is Heartburn a Sign of Esophageal Cancer? | Memorial Sloan Kettering Cancer Centerhttps://www.mskcc.org/news/when-heartburn-signals-cancer-risk
When patients come to me after they find out they have esophageal cancer, most of them have had GERD for a long time, sometimes decades, says Daniela Molena, Director of MSK’s Esophageal Surgery Program. […] Gastroesophageal reflux disease (GERD) is a potentially serious condition that, untreated, can lead to esophageal cancer. […] heartburn can be a symptom of gastroesophageal reflux disease (GERD), a severe form of acid reflux that if left untreated can ultimately lead to esophageal cancer. […] GERD is a risk factor for esophageal cancer and a symptom of a very rare subtype of pancreatic cancer, it is not associated with other types of cancer, like colon cancer, stomach cancer, or lung cancer. […] After someone has had GERD for many years, it can advance to a condition called Barretts esophagus.
- #2 Heartburn: What It Feels Like, Causes & Treatmenthttps://my.clevelandclinic.org/health/diseases/9617-heartburn-overview
Heartburn occurs when acid from your stomach refluxes up into your esophagus. […] Heartburn is caused by stomach acid rising into your esophagus (reflux), which runs through your chest, close to your heart. […] Heartburn occurs when stomach juices, including acids and enzymes, backwash into your esophagus. […] Different things can cause your lower esophageal sphincter to weaken or relax too much, such as inhaling smoke, extra abdominal pressure from body weight, tight clothing or pregnancy, hiatal hernia, a heavy meal that stretches your stomach and stays in it longer, indigestion and gas, lying down too soon after eating, certain foods, and certain medications. […] If heartburn is relatively new to you, and you haven’t recently changed your diet or lifestyle, you may be getting it for other reasons that can develop gradually over time.
- #2 Acid Reflux & GERD: Symptoms, What It Is, Causes, Treatmenthttps://my.clevelandclinic.org/health/diseases/17019-acid-reflux-gerd
Your LES is a circular muscle that opens when you swallow and then closes again to keep substances in your stomach. It also opens a little to let gas bubbles out when you’re burping or have hiccups. […] Acid reflux happens when your LES weakens or relaxes enough to let acid pass. Some temporary things can relax your LES, like lying down after a large meal. But if you have GERD, it means your LES is relaxing often. […] Many things can contribute to weakening your LES, either temporarily or permanently. Sometimes occasional acid reflux turns into chronic GERD when these factors overlap or persist for a long time. […] Common causes of acid reflux and GERD include: Hiatal hernia. A hiatal hernia happens when the top of your stomach pushes up through the hole in your diaphragm where your esophagus passes through. It squeezes in next to your esophagus, compressing them both and trapping acid. It also moves your LES above your diaphragm, where it loses some of its muscular support. Hiatal hernias are very common, especially as you get older. They usually occur gradually, and they can gradually worsen.
- #2 Heartburn: MedlinePlus Medical EncyclopediaLockhttps://medlineplus.gov/ency/article/003114.htm
Heartburn is a painful burning feeling just below or behind the breastbone. Most of the time, it comes from the esophagus. The pain often rises in your chest from your stomach. It may also spread to your neck or throat. […] Almost everyone has heartburn at some time. If you have heartburn very often, you may have gastroesophageal reflux disease (GERD). […] Normally when food or liquid enters your stomach, a band of muscle at the lower end of your esophagus closes off the esophagus. This band is called the lower esophageal sphincter (LES). If this band does not close tightly enough, food or stomach acid can back up (reflux) into the esophagus. The stomach contents can irritate the esophagus and cause heartburn and other symptoms. […] Heartburn is more likely if you have a hiatal hernia. A hiatal hernia is a condition which occurs when the top part of the stomach pokes into the chest cavity. This weakens the LES so that it is easier for acid to back up from the stomach into the esophagus. […] Pregnancy and many medicines can bring on heartburn or make it worse. […] Talk to your health care provider if you think one of your medicines may be causing heartburn. Never change or stop taking medicine without talking to your provider first.
- #2 Heartburn and acid refluxhttps://www.nhs.uk/conditions/heartburn-and-acid-reflux/
Heartburn is a burning feeling in the chest caused by stomach acid travelling up towards the throat (acid reflux). If it keeps happening, it may be called gastro-oesophageal reflux disease (GORD). […] Sometimes it’s caused or made worse by: certain food and drink such as coffee, tomatoes, alcohol, chocolate and fatty or spicy foods; being overweight; smoking; pregnancy; stress and anxiety; an increase in some types of hormones, such as progesterone and oestrogen; some medicines, such as anti-inflammatory painkillers (like ibuprofen); a hiatus hernia when part of your stomach moves up into your chest; a stomach ulcer; a bacterial infection in your stomach. […] If you have acid reflux, a GP may prescribe a medicine called a proton pump inhibitor (PPI) that reduces how much acid your stomach makes.
- #2 Heartburn: Symptoms, Causes, Medications, Treatment & Preventionhttps://www.rxlist.com/heartburn/drugs-condition.htm
A hiatal hernia where a portion of the stomach lies within the chest instead of the in the abdomen can affect the way the LES works and is a risk factor for reflux. […] Pregnancy can cause increased pressure within the abdominal cavity and affect LES function and predispose it to reflux. […] Obesity may also cause increased pressure in the abdomen, and thus reflux in the same way. […] Primary diseases of the esophagus can also present with heartburn as a symptom. These include, among others, scleroderma and sarcoidosis.
- #2 Heartburn: Symptoms, Causes, and How to Get Rid of Ithttps://www.healthline.com/health/heartburn
Heartburn typically occurs when contents from the stomach back up into the esophagus, a tube that carries food and fluids from the mouth to the stomach. […] However, in some people, the lower esophageal sphincter doesn’t function properly. This allows the stomach contents to leak back into the esophagus, which can cause heartburn. […] Certain conditions and other factors may make it more likely for you to experience heartburn. Risk factors include: […] Hiatal hernia: A hiatal hernia occurs when the upper part of your stomach penetrates through the diaphragm, usually by way of a weakness or tear. […] Pregnancy: Heartburn is common during pregnancy, especially during the third trimester. […] Smoking: Smoking is associated with an increased chance of developing gastroesophageal reflux disease (GERD).
- #2 What Causes Heartburn (Acid Reflux)? | Cedars-Sinaihttps://www.cedars-sinai.org/blog/what-causes-heartburn-and-acid-reflux.html
Heartburn happens because stomach acid becomes backed up in the esophagus, which moves food from your mouth to your stomach. […] The burning sensation is usually the result of stomach acid leaking up into the esophagus through a flaw in a valve known as the lower esophageal sphincter (LES), which connects the esophagus and the stomach. […] Many things can trigger heartburn. The most common cause is food that’s acidic or high in fat like citrus fruits, tomatoes, onions, chocolate, coffee, cheese, and peppermint. […] Other sources of heartburn include aspirin or ibuprofen, as well as some sedatives and blood pressure medications. […] Tobacco in cigarettes is known to affect LES function too; cigarette smoking relaxes the muscle, which can result in heartburn. […] Being overweight or pregnant can also trigger heartburn due to added pressure on the abdomen and stomach.
- #2 Is sudden heartburn a cause for concern? Causes and treatmenthttps://www.medicalnewstoday.com/articles/why-am-i-getting-heartburn-all-of-a-sudden
A person may get heartburn all of a sudden as a result of eating certain foods, some eating patterns, drinking alcohol, and smoking. Stress, anxiety, certain medications, and some medical conditions can also cause it. […] The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) notes that some foods and drinks can bring on symptoms of heartburn. […] These types of foods can irritate the lining of the esophagus, which can lead to heartburn. […] Heartburn can develop as a result of eating a large meal, eating a meal late at night, eating a meal that is calorie dense, lying down too soon after eating, and eating too quickly. […] According to research from 2019, eating large or calorie dense meals can cause gastric distention, or the enlargement of the stomach. […] The American Psychological Association notes that stress can lead to heartburn.
- #2 Heartburn – Women’s Health – Associates for Women’s Medicine – Syracuse NY Gynecologist, Gynecology, Obstetrics, OBGYN, OB Physicians, Syracuse New York, Fayetteville, North Syracuse, LiverpoolHeartburnhttps://www.afwomensmed.com/health-library/hw-view.php?DOCHWID=hrtbn
A hiatal hernia. It occurs when a small portion of the stomach pushes upward through the diaphragm. […] Feeling stressed. Some people have more heartburn when they are stressed. […] Heartburn can be caused by gastroesophageal reflux disease (GERD). […] Heartburn may also be related to an infection with Helicobacter pylori (H. pylori) bacteria. […] Many prescription and nonprescription medicines can cause heartburn. A few examples are: Aspirin, ibuprofen (such as Advil or Motrin), and naproxen (such as Aleve). […] Caffeine and alcohol also can cause heartburn.
- #2 Heartburn: Causes, Symptoms, and Treatmenthttps://www.webmd.com/heartburn-gerd/understanding-heartburn-basics
Heartburn symptoms can start when the lower esophageal sphincter (LES) valve at the bottom of your esophagus doesn’t close correctly. […] We don’t know what causes the LES valve to weaken, but it could be caused by eating big meals too often, if you’re overweight, or you have a hiatal hernia (a hernia in your upper stomach that pushes through your diaphragm). […] Certain foods can relax your LES or increase stomach acid, including: Tomatoes, Citrus fruits, Garlic and onions, Chocolate, Coffee or caffeinated products, Alcohol, Peppermint, Foods high in fats and oils. […] You’re also more likely to get heartburn if you: Eat right before bedtime, Smoke, vape, or use tobacco products, Wear tight-fitting clothing or belts, Lie down or bend over after eating, Are stressed out, Are pregnant, Take certain medications, including some antibiotics and nonsteroidal anti-inflammatory drugs (NSAIDs), Are constipated.
- #2 What really causes heartburn? | Logansport Memorial HospitalSearchSearchFacebookYouTubeBlogTwitterhttps://www.logansportmemorial.org/blog/what-really-causes-heartburn
Heartburn is the common name for the burning in your neck and chest caused when your body pushes digestive acid up from your stomach into your esophagus, also known as acid reflux. […] For some people, they only experience heartburn now and then, and the typical trigger is due to eating certain acidic, fatty, or spicy foods, eating late at night before going to bed, or having a big meal. […] Though getting heartburn infrequently usually isnât a cause for alarm, you can make small but significant dietary changes to help prevent future occurrences. […] To lessen your chance of experiencing heartburn after mealtimes, consider avoiding or limiting your consumption of aggravating foods, including: high-fat foods, spicy foods, alcohol, black pepper, garlic, raw onions, chocolate, citrus foods, tomatoes, caffeine, acidic fruit juices, carbonated beverages, peppermint, foods with the additive carrageenan, like non-dairy milk.
- #2 Heartburn: Causes, Symptoms & Treatmenthttps://www.rosemaryhealth.com.au/guides/heartburn-causes-symptoms-treatment
Heartburn is the unpleasant and frequently painful sensation caused by acid rushing up your oesophagus and into your mouth. […] Heartburn discomfort is exacerbated by eating a large fatty meal, eating and then lying down for a snooze, or bending over. […] When stomach acid enters the oesophagus, it causes irritation, burning, pain, and inflammation – also known as heartburn. […] Acid reflux causes the symptom, heartburn. Recurrent acid reflux can cause GORD. […] Certain foods and beverages, alcohol, and some medications cause heartburn. […] Foods and drinks that relax the lower oesophageal sphincter (LOS) and cause heartburn and acid reflux include: Caffeinated beverages like coffee or tea, Carbonated drinks, Chocolate contains methylxanthine, which is similar to caffeine, Fried, greasy or fatty foods, Peppermint, Spicy foods, Onions, Alcohol.
- #2 What Causes Heartburn? | PEPCID®https://www.pepcid.com/understanding-heartburn/what-causes-heartburn
Controlling your heartburn triggers can help reduce how often you experience heartburn, but everyones triggers may be different. […] There are many reasons for heartburn, but it is often linked to the lower esophageal sphincter (LES) relaxing or weakening and letting acid escape from the stomach into the esophagus. […] Common causes of heartburn include certain types of foods, medications, and some lifestyle choices. […] Smoking weakens the lower esophageal sphincter (LES) and can also contribute to other digestive conditions, as well as cause cancer. […] Caffeinated beverages, coffee, caffeinated teas, sodas, and energy drinks are common heartburn triggers. […] Red wine is worse than white wine as a heartburn trigger, though both increase stomach acid production. […] Sugary, heavy, greasy, and fatty foods are harder to digest, which means your stomach needs to make more acid to break them down. […] Lying in a horizontal position can make it easier for acid to creep up out of your stomach into your esophagus. […] Stress can make heartburn worse, as well as make you reach for triggers like cigarettes, alcohol, or greasy comfort food.
- #2 What Causes Heartburn? How to Relieve Heartburn – Scripps Healthhttps://www.scripps.org/news_items/6857-what-causes-heartburn-how-to-beat-the-burn-podcast
There are a variety of triggers. First lets talk about dietary triggers. They are acidic foods, such as spicy foods, fatty foods, fried foods, caffeinated beverages and carbonated beverages. Cigarette smoking can make it worse. Alcohol relaxes the lower esophageal sphincter and can make reflux worse. […] Anatomic things can trigger heartburn. For example, if you eat a large meal, it distends the stomach, especially if you lay down. Reflux happens more commonly at night. […] Other things would be obesity, even pregnancy. Certain medications, aspirin, non-steroidal anti-inflammatants, ibuprofen, Motrin, Advil and Aleve. Different medications used to treat osteoporosis, such as Fosamax, Actonel and other bisphosphonates. Chemotherapeutic drugs. There are a variety of exacerbating factors.
- #2 What Causes Heartburn? How to Relieve Heartburn – Scripps Healthhttps://www.scripps.org/news_items/6857-what-causes-heartburn-how-to-beat-the-burn-podcast
Weight loss has proven to be helpful. Elevating the height of your bed is helpful, six to eight inches. You can put blocks under the top of the bed or wedges that elevate the bed. Eat at least three hours or more prior to bedtime. If you eat right before bedtime and then you lay down, your stomach gets distended and then reflux is more likely. Then of course, there are a variety of medications. […] A lot of the medications that used to be prescription are fairly safe and are now over the counter. But the most commonly used ones that have been out there forever are your antacids, things like Tums and Mylanta. They just neutralize the stomach acid. The next step up would be H2 blockers, which are Pepcid, Zantac, [which are famotidine and ranitidine respectively]. Those bind to cells in the stomach.
- #2 What Causes Heartburn? | TUMShttps://www.tums.com/about-heartburn/causes/
Workouts that put pressure on the abdomen, such as heavy lifting and stomach crunches, can increase the risk of heartburn as they can relax the lower esophageal sphincter (LES) muscle, which can lead to food or stomach acid coming back up into the esophagus. […] Some types of food can trigger heartburn. Spicy foods, citrus fruits such as oranges and lemons, and fried or high-fat foods have been found to cause heartburn. […] Even healthier high-fat foods including avocados and cheese pose a risk. […] Avoiding coffee and caffeinated beverages such as sports energy drinks can help reduce the risk of heartburn. […] Some common medications, including prescription and over-the-counter drugs, can cause heartburn as a side effect. […] Indigestion and heartburn are common in pregnancy, especially during the second and third trimesters.
- #2 Symptoms & Causes of GER & GERD – NIDDKhttps://www.niddk.nih.gov/health-information/digestive-diseases/acid-reflux-ger-gerd-adults/symptoms-causes
Your lower esophageal sphincter and diaphragm most often prevent GER, which is when stomach contents come back up into your esophagus. […] GERD may develop if your lower esophageal sphincter becomes weak or relaxes when it shouldn’t. Factors that may affect the lower esophageal sphincter and lead to GERD include being overweight or having obesity, being pregnant, smoking or inhaling secondhand smoke. […] Some medicines can cause GERD or make GERD symptoms worse. Examples include benzodiazepines, sedatives that make you calmer or sleepy, calcium channel blockers, which are used to treat high blood pressure, certain asthma medicines, nonsteroidal anti-inflammatory drugs (NSAIDs), tricyclic antidepressants. […] A hiatal hernia can also increase the chance of getting GERD or make GERD symptoms worse. A hiatal hernia is a condition in which the opening in your diaphragm lets the upper part of the stomach move up into your chest.
- #2 Heartburn Triggers: What’s Burning You?https://hunterdongastro.com/heartburn-triggers-whats-burning-you/
If your LES doesnt tighten as it should, there are often two things that contribute to the problem. One is overeating, which puts too much food in your stomach. Another is too much pressure on your stomach, often due to obesity, pregnancy, or constipation. […] Fatty foods are big no-nos if you suffer from heartburn. High-fat foods sit around in your belly longer. This makes your stomach produce more acid, irritating your digestive system. And fatty and greasy foods lead to a lazy, relaxed LES. So not only do you have more irritating stomach acids, youre more likely to have the contents splash back up your throat resulting in heartburn pain. […] Many different medications can trigger heartburn or make heartburn worse. An aspirin here or there is not likely to lead to that fiery feeling. But regular use of aspirin or a popular class of painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs) may irritate the esophagus. […] Several different types of blood pressure medicines can also cause heartburn. Many blood pressure and heart disease medicines, including calcium channel blockers and nitrates, relax the LES muscle, making it easy for your stomach acids to retreat backward.
- #2 Heartburn (GERD): Facts, Treatment, Causes, Symptoms & Preventionhttps://www.emedicinehealth.com/heartburn_faqs/article_em.htm
Many prescription medications can loosen the lower esophageal sphincter, including certain blood pressure and heart medications and the asthma drug theophylline. […] Excess stomach acid in the esophagus can cause ulcers, damage to the inner layers of the esophageal wall, and narrowing (stricture and swallowing difficulty). […] Regurgitated stomach acid can damage the respiratory tract, causing asthma, hoarseness, chronic cough, sore throat, or tooth damage (acid destroys the enamel on teeth). […] If the acid exposure continues for long periods of time, the esophagus becomes thick and damaged. A person may then have difficulty swallowing and food becomes stuck. […] Many substances directly irritate the lining of the esophagus and can contribute to heartburn. These include spicy foods, citrus fruits and juices, tomatoes and tomato sauces, cigarette smoke, aspirin, and ibuprofen (with brand names such as Motrin and Advil).
- #2 Heartburn: Causes, Symptoms & Treatmenthttps://www.rosemaryhealth.com.au/guides/heartburn-causes-symptoms-treatment
Many medications can cause heartburn, but common offenders include: Antibiotics like tetracycline, Aspirin, Anti-inflammatories such as voltaren and nurofen, Asthma medications, Corticosteroids, Potassium, Iron supplements, Vitamin C. […] A hiatal hernia occurs when at least part of the stomach is pushed through the diaphragm from the abdomen into the chest. […] Because progesterone, a female sex hormone, relaxes the LOS, heartburn can worsen during pregnancy. […] Obesity, as well as wearing tight-fitting clothing or a belt, raises abdominal pressure causing heartburn.
- #2 Heartburn: Symptoms, Causes, Medications, Treatment & Preventionhttps://www.rxlist.com/heartburn/drugs-condition.htm
Heartburn is actually a symptom of GERD (gastroesophageal reflux disease) and is caused by acid refluxing back into the esophagus. […] Heartburn is a symptom of a common medical condition (GERD) that affects up to 20% of the population. […] Heartburn is actually a symptom of GERD (gastroesophageal reflux disease) and is caused by acid refluxing back into the esophagus. Risk factors include those that increase the production of acid in the stomach, as well as structural problems that allow acid reflux into the esophagus. […] Some common foods that we eat and drink, stimulate increased stomach acid secretion setting the stage for heartburn. […] Smoking and the consumption of high-fat content foods tend to affect the function of the lower esophageal sphincter (LES), causing it to relax from the stomach and allow acid to reflux into the esophagus.
- #2 Constant Heartburn: Causes, Symptoms, and Treatmenthttps://www.verywellhealth.com/constant-heartburn-5215258
Heartburn occurs when stomach acid backs up into the esophagus, causing burning, irritation, or pain in the chest. […] Constant heartburn may indicate an underlying health issue that should be investigated. […] Gastroesophageal reflux disease (GERD) can cause constant heartburn that occurs more than twice a week over a period of several weeks. […] GERD is very common in the United States, affecting approximately 20% of the population. […] There are several gastrointestinal diseases that can cause constant or recurrent heartburn. […] Esophagitis is a broad term that refers to any inflammation of the esophagus. […] Esophagitis can be caused by many things, including viruses or other germs, medications, or frequent vomiting. […] Constant heartburn can be a symptom of an underlying condition, such as GERD, esophagitis, or other gastrointestinal disorders. […] Experiencing heartburn more than once a week over a period of several weeks may indicate an underlying condition.
- #2https://www.aurorahealthcare.org/services/gastroenterology-colorectal-surgery/gastroesohageal-reflux-gerd
Acid reflux is caused by a problem with a muscle at the bottom of the esophagus (the esophageal sphincter). Normally, the muscle relaxes to let food and liquid into the stomach, then it closes. When the muscle doesn’t close correctly, stomach acid can back up through the partial opening leading to acid reflux symptoms. […] Frequent, long-term heartburn can allow acid to wear away the lining of the esophagus and cause problems such as scar tissue that narrows the esophagus, sores (peptic ulcers) in the esophagus or even precancerous changes to the esophagus (Barrett’s esophagus). […] Having some of the factors listed below can mean you’re at increased risk for gastroesophageal reflux disease. […] Medications will reduce symptoms for most people, but not all. And they don’t repair the damage done by gastroesophageal reflux disease over the long term.
- #2 Causes of GERD – chemical and anatomicalhttps://www.gerdhelp.com/about-gerd/causes/
Any one of the following factors, or a combination of these factors, can result in disruption of the gastroesophageal valve and abnormal exposure of the esophagus to acid reflux: Genetic: Anatomy varies from person to person. Some people naturally have valves that function less competently than others. Injury to the upper chest: Often the result of a sports-related injury or a traumatic accident, these incidents can cause the valve to lose its shape. Obesity or diet related issues: Excess weight can cause distortion of normal anatomy. Age: As people age, musculature can lose its integrity and affect the anatomy in the esophagus and stomach area.
- #2 Causes and Diagnoses of Gastroesophageal Reflux Disease (GERD) | Northwestern Medicinehttps://www.nm.org/conditions-and-care-areas/gastroenterology/gastroesophageal-reflux-disease/causes-and-diagnoses
The exact cause of GERD is unknown. […] GERD is more likely to develop in people who have a hiatal hernia. This is when the upper part of the stomach moves into the lower esophagus. […] There are certain factors that increase your risk of developing GERD, including: Obesity, Pregnancy, Smoking. […] Some foods may make your reflux symptoms worse, including: Citrus fruits, Chocolate, Caffeinated drinks, Alcoholic beverages, Fatty and/or fried foods, Garlic and/or onions, Mint, Spicy foods, Tomato-based foods such as chili, spaghetti sauce, pizza and salsa.
- #2https://www.koruhastanesi.com/causes-of-heartburn-3471-5
Heartburn occurs when acid refluxes back into the esophagus. […] GERD (gastroesophageal reflux disease) is a much more common problem than gastritis. It occurs when acid refluxed back up into the esophagus, causing symptoms such as heartburn, regurgitation, nausea, vomiting, and difficulty swallowing. […] There are several different causes of heartburn. One of the most common causes is hiatal hernia. […] GORD is also known as gastroesophageal reflux disease (GERD). It occurs when acid from the stomach flows back up into the esophagus causing discomfort. […] If you suffer from heartburn, you might think that you have an ulcer or other digestive problem. However, heartburn is not caused by an ulcer. Instead, it is due to the flow of gastric juices back into the esophagus. […] In some people, the cells lining the lower part of the esophagus become abnormal (called Barretts esophagus). This condition can lead to cancer.
- #2 Heartburn – Wikipediahttps://en.wikipedia.org/wiki/Heartburn
Heartburn is a burning sensation felt behind the breastbone. It is a symptom that is commonly linked to acid reflux and is often triggered by food, particularly fatty, sugary, spicy, chocolate, citrus, onion-based and tomato-based products. […] Causes include acid reflux, gastroesophageal reflux disease (GERD), damage to the esophageal lining, bile acid, mechanical stimulation to the esophagus, and esophageal hypersensitivity. […] Acid reflux is a common cause of heartburn but is not the only etiology. […] The exact causes of heartburn are not fully understood, but they likely involve multiple factors, including chemical irritation, pressure on the esophagus, and increased sensitivity to pain. […] Bile acid rising into the esophagus can cause heartburn, though bile acid is slower and less intense than stomach acid exposure. […] Mechanical stimulation may play a role in heartburn. […] Esophageal hypersensitivity plays a major role in heartburn, especially in those with GERD who have normal acid levels.
- #2 Why Do I Have Heartburn? 11 Reasonshttps://www.health.com/condition/gerd/9-serious-conditions-that-can-feel-like-heartburn
Acid reflux, allergies, asthma, and certain medicines may cause esophagitis. […] GERD is a chronic health condition that causes heartburn and regurgitation. […] Gastroparesis, or gastric emptying, happens when stomach muscles become too weak to pass food into your small intestine. […] A hiatal hernia can impact the lower esophageal sphincter by creating a gap between your esophagus and stomach. […] The female sex hormones estrogen and progesterone elevate during pregnancy. […] Those high hormone levels may affect the function of the lower esophageal sphincter, creating a gap between your esophagus and stomach. […] Stomach ulcers may cause symptoms like heartburn. […] Some causes of stomach ulcers include bacterial infections, prolonged non-steroidal anti-inflammatory drug (NSAID) use, and tumors.
- #2 Causes of GERD – About GERDhttps://aboutgerd.org/what-is/introduction-to-gerd/causes-of-gerd/
Reflux occurs when that barrier is relaxed at inappropriate times, is weak, or is otherwise compromised. […] There is no known single cause of gastroesophageal reflux disease (GERD). It occurs when the esophageal defenses are overwhelmed by gastric contents that reflux into the esophagus. […] Gastroesophageal reflux occurs when the LES barrier is somehow compromised. […] A hiatal hernia may decrease the sphincter pressure necessary to maintain the anti-reflux barrier. […] The extent of injury to the esophagus and the degree of severity of GERD depends on the frequency of reflux, the amount of time the refluxed material stays in the esophagus, and the quantity of acid in the esophagus.
- #2 What to eat when you have chronic heartburn – Harvard Healthhttps://www.health.harvard.edu/diseases-and-conditions/what-to-eat-when-you-have-chronic-heartburn
One of the most common causes of heartburn is called gastroesophageal reflux disease (GERD). It occurs when stomach acid backs up into the esophagus, the tube connecting the mouth and stomach, usually because the ring-like muscles that prevent backflow stop working properly. […] Medications to treat GERD reduce stomach acid. Antacid pills and liquids have been around the longest. Proton-pump inhibitors (PPIs), such as omeprazole (Prilosec) or lansoprazole (Prevacid), and H2 blockers, such as cimetidine (Tagamet) or famotidine (Pepcid), are available over the counter. […] You can limit and perhaps avoid medication to control GERD symptoms by losing weight if necessary, eating smaller meals and avoiding food triggers.
- #2 Heartburn: Causes, Investigation, Treatmenthttps://www.drchiragthakkar.com/blog/heartburn-causes-investigation-treatment-ahmedabad-acid-reflux-gerd/
Heartburn happens when your stomach acid flows back into your esophagus or food pipe. This causes an uncomfortable burning feeling in your chest that can move up to your neck and throat. […] Several factors may lead to heartburn or make it feel worse. These include: […] Medical reasons: Hiatal hernia (when the stomach bulges up into the chest), Gastroesophageal reflux disease (GERD), Obesity, Use of certain medicines, especially some anti-inflammatory drugs and aspirin, Pregnancy. […] Severe, chronic heartburn/GERD has been linked to inflammation and narrowing of the esophagus, respiratory problems, chronic cough, and Barretts esophagus, which may lead to esophageal cancer. […] GERD and Acid reflux are lifestyle diseases, and hence we are noticing a massive increase in the incidence of heartburn. […] Many patients who have a more severe problem with their LES valve may need long term medications. […] There are a small number of GERD patients, who have a more pronounced mechanical problem with LES valve and hiatus hernia.
- #3 What Causes Heartburn? How to Relieve Heartburn – Scripps Healthhttps://www.scripps.org/news_items/6857-what-causes-heartburn-how-to-beat-the-burn-podcast
Everyone is susceptible. But you certainly have risk factors that predispose and increase your risk. Obesity is one. It causes some compression and increases the pressure there. Pregnancy is another issue. Cigarette smoking, medications and alcohol are other risk factors. […] Also, there is an anatomic reason. People can have a hiatal hernia, which is fairly common. In a hiatal hernia, you have your esophagus, and then you have your diaphragm, and then underneath that is your stomach. You have a muscle right here called your lower esophageal sphincter that relaxes when you eat food and then contracts so that stomach contents dont reflux back up. Your diaphragm helps pinch that lower esophageal sphincter. What happens with a hiatal hernia is the stomach actually leaks up into the chest cavity and reflux happens more easily.
- #3 Is sudden heartburn a cause for concern? Causes and treatmenthttps://www.medicalnewstoday.com/articles/why-am-i-getting-heartburn-all-of-a-sudden
Additionally, people may turn to comfort foods high in fat, sugar, or salt when stressed, which can also bring on heartburn. […] The NIDDK notes that the following medications can result in heartburn: benzodiazepines, some asthma medications, tricyclic antidepressants, calcium channel blockers, and nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen. […] Certain medical conditions can cause heartburn. These include hiatal hernia, gastroesophageal reflux disease (GERD), and peptic ulcer disease. […] Heartburn is common during pregnancy, with an incidence of 17-45% in pregnant women. […] A person without a history of heartburn may start experiencing it due to changes in diet or lifestyle, certain medications, medical conditions, or stress and anxiety.
- #3 When Is Heartburn a Sign of Esophageal Cancer? | Memorial Sloan Kettering Cancer Centerhttps://www.mskcc.org/news/when-heartburn-signals-cancer-risk
When patients come to me after they find out they have esophageal cancer, most of them have had GERD for a long time, sometimes decades, says Daniela Molena, Director of MSK’s Esophageal Surgery Program. […] Gastroesophageal reflux disease (GERD) is a potentially serious condition that, untreated, can lead to esophageal cancer. […] heartburn can be a symptom of gastroesophageal reflux disease (GERD), a severe form of acid reflux that if left untreated can ultimately lead to esophageal cancer. […] GERD is a risk factor for esophageal cancer and a symptom of a very rare subtype of pancreatic cancer, it is not associated with other types of cancer, like colon cancer, stomach cancer, or lung cancer. […] After someone has had GERD for many years, it can advance to a condition called Barretts esophagus.