Materiały źródłowe

• #1 Endometrial cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/endometrial-cancer/diagnosis-treatment/drc-20352466

  Endometrial cancer is usually first treated with surgery to remove the cancer. This may include removing the uterus, fallopian tubes and ovaries. Other treatment options may include radiation therapy or treatments using medicines to kill the cancer cells. Options for treating your endometrial cancer will depend on the characteristics of your cancer, such as the stage, your general health and your preferences. […] Treatment for endometrial cancer usually involves an operation to remove the uterus, called a hysterectomy. Treatment also usually includes the removal of the fallopian tubes and ovaries, called a salpingo-oophorectomy. A hysterectomy makes it impossible for you to become pregnant in the future. Also, once your ovaries are removed, you’ll experience menopause if you haven’t already.

• #1 Endometrial Cancer Treatment Landing Page | American Cancer Society | American Cancer Society

  https://www.cancer.org/cancer/types/endometrial-cancer/treating.html

  If you’ve been diagnosed with endometrial cancer, your cancer care team will discuss your treatment options with you. It’s important to weigh the benefits of each treatment option against the possible risks and side effects. […] The most common types of treatment for women with endometrial cancer are: Surgery for Endometrial Cancer, Radiation Therapy for Endometrial Cancer, Chemotherapy for Endometrial Cancer, Hormone Therapy for Endometrial Cancer, Targeted Therapy for Endometrial Cancer, Immunotherapy for Endometrial Cancer. […] Surgery is the main treatment for most women with this cancer. But in some cases, a more than 1 kind of treatment may be used. The choice of treatment depends largely on the type of cancer and stage of the disease when it’s found. […] Depending on the type and stage of the endometrial cancer, you may need more than one type of treatment.

• #1 Treatment Choices for Endometrial Cancer, by Stage | American Cancer Society

  https://www.cancer.org/cancer/types/endometrial-cancer/treating/by-stage.html

  The stage (extent) of endometrial cancer is the most important factor in choosing treatment. But other factors can also affect your treatment options, including the type of cancer, your age and overall health, and whether you want to be able to have children. Tests done on the cancer cells are also used to find out if certain treatments, like hormone, immunotherapy, and targeted therapy, might work. […] Surgery is the first treatment for almost everyone with endometrial cancer. The operation includes removing the uterus, fallopian tubes, and ovaries. (This is called a total hysterectomy bilateral salpingo-oophorectomy or TH/BSO). Lymph nodes from the pelvis and around the aorta may also be removed (a pelvic and para-aortic lymph node dissection [LND] or sampling) and tested for cancer spread. Pelvic washings may be done, too. The tissues removed at surgery are tested to see how far the cancer has spread (staging). Depending on the stage of the cancer, other treatments, such as radiation and/or chemotherapy may be recommended.

• #1 Surgery for Uterine (Endometrial) Cancer | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/uterine-endometrial/treatment/surgery

  The most common approach to this surgery total abdominal hysterectomy can be done by traditional means or through a minimally invasive strategy that offers such benefits as reduced risk for infection and faster recovery. […] With laparoscopic surgery, the surgeon first examines the pelvic cavity with a laparoscope a thin, lighted tube with a video camera at its tip which projects an image onto a large viewing screen. […] Some women whose advanced uterine cancer has spread to other abdominal organs may need an extensive surgery known as pelvic exenteration. This radical procedure is reserved for women with limited treatment options. In this surgery, we remove all reproductive organs.

• #1 Treatment Choices for Endometrial Cancer, by Stage | American Cancer Society

  https://www.cancer.org/cancer/types/endometrial-cancer/treating/by-stage.html

  For some who still want to be able to get pregnant, surgery may be put off for a time and other treatments tried instead. […] If a patient isn’t well enough to have surgery, other treatments, like radiation, will be used. […] Standard treatment includes surgery to remove and stage the cancer. Sometimes this is the only treatment needed. The patient is then closely watched for signs that the cancer has come back (recurred). […] For those with higher grade tumors, radiation will likely be recommended after surgery. Vaginal brachytherapy (VB), pelvic radiation, or both can be used. […] Those who cannot have surgery because of other medical problems or age are often treated with just radiation (external radiation and/or vaginal brachytherapy). […] For those who still want to have children, surgery may be postponed while progestin therapy is used to treat the cancer. Progestin treatment can cause the cancer to shrink or even go away for some time, giving them a chance to get pregnant.

• #1 Endometrial cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/endometrial-cancer/diagnosis-treatment/drc-20352466

  Radiation therapy uses powerful energy to kill cancer cells. The energy can come from X-rays, protons or other sources. In certain situations, radiation therapy may be recommended before surgery. Radiation therapy can shrink a tumor and make it easier to remove. […] Chemotherapy uses strong medicines to kill cancer cells. Some people receive one chemotherapy medicine. Others receive two or more medicines together. Most chemotherapy medicines are given through a vein, but some are taken in pill form. These medicines enter the bloodstream and then travel through the body, killing cancer cells. […] Hormone therapy involves taking medicines to lower the hormone levels in the body. In response, cancer cells that rely on hormones to help them grow might die. Hormone therapy may be an option if you have advanced endometrial cancer that has spread beyond the uterus.

• #1 Radiation Therapy for Cancer of the Uterus | Cancer Council NSW

  https://www.cancercouncil.com.au/uterine-cancer/treatment/radiotherapy/

  Radiation therapy for cancer of the uterus is commonly used as an additional treatment after surgery to reduce the chance of the disease coming back. This is called adjuvant therapy. […] In some cases, radiation therapy may be recommended as the main treatment (e.g. when other health conditions mean you are not well enough for a major operation). […] There are 2 main ways of delivering radiation therapy: internally and externally. […] Internal radiation therapy may be used after a hysterectomy to deliver radiation directly to the top of the vagina (vaginal vault) from inside your body. […] External beam radiation therapy (EBRT) directs the radiation at the cancer and surrounding tissue from outside the body. […] For cancer of the uterus, the lower abdomen and pelvis are treated, but if the cancer has spread (metastasised), other areas may also be treated. […] If you are having EBRT, you will probably have daily treatments, Monday to Friday, for 5–6 weeks as an outpatient. It’s very important that you attend all of your scheduled sessions to ensure you receive enough radiation to make the treatment effective.

• #1

  https://www.nhs.uk/conditions/womb-cancer/treatment/

  Womb cancer is usually treatable when its found early. […] The treatment you have for womb cancer will depend on: the size of the cancer, where it is, if it has spread, your general health. […] It will usually include surgery, chemotherapy or radiotherapy. It may also include treatment with targeted medicines to treat the cancer. […] Surgery is often the main treatment for womb cancer. Especially if the cancer is found early. […] If the cancer has spread to other parts of your body, you may need to have a combination of surgery, radiation and chemotherapy to remove as much of the cancer as possible. […] Radiotherapy uses high-energy rays of radiation to kill cancer cells. […] You may have radiotherapy for womb cancer: as the main treatment if you cannot have surgery, if the cancer is large or has spread, after surgery to help stop the cancer coming back, sometimes with chemotherapy (chemoradiotherapy).

• #1

  https://www.nhs.uk/conditions/womb-cancer/treatment/

  Chemotherapy is medicine that kills cancer cells. […] You may have chemotherapy for womb cancer: on its own, or with radiotherapy (chemoradiotherapy), as the main treatment for womb cancer if you cannot have surgery, after surgery (usually with radiotherapy) to help stop the cancer coming back, to help slow the cancer down and ease symptoms if it has spread to other parts of your body. […] You may have hormone therapy to ease symptoms or shrink and control the cancer if it has spread outside your womb to other parts in your body. […] This treatment is suitable if youre not well enough to have surgery or radiotherapy. […] Immunotherapy medicines help your immune system to find and kill cancer cells. […] This treatment may be suitable if you have advanced womb cancer or if womb cancer has come back after treatment.

• #1 Uterine Cancer Treatment and Outlook

  https://www.healthline.com/health/cancer/uterine-cancer-treatment

  Treatment for uterine cancer will most likely include some form of surgery. Other options may include chemotherapy, radiation, targeted therapy, and hormone therapy. […] Your doctor will take into account the above factors when recommending which of the following treatment options are appropriate for you. […] Surgery is often the first treatment for many people with uterine cancer. Typically, surgery for uterine cancer involves an operation called a total hysterectomy bilateral salpingo-oophorectomy. […] Chemotherapy uses drugs that disrupt the growth of rapidly dividing cells, such as cancer cells. It may be used for all stages of uterine cancer, specifically: before surgery to help shrink the cancer, after surgery to help kill remaining cancer cells when there’s a higher risk of the cancer coming back, as a main part of treatment if you cannot or choose not to have surgery.

• #1 Chemotherapy for uterine cancer | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/uterine/treatment/chemotherapy

  Chemotherapy uses anticancer, or cytotoxic, drugs to destroy cancer cells. It is sometimes used to treat uterine cancer. Your healthcare team will consider your personal needs to plan the drugs, doses and schedules of chemotherapy. You may also receive other treatments. […] Chemotherapy is sometimes combined with radiation therapy to treat some types of uterine cancer. This is called chemoradiation. The 2 treatments are given during the same time period. […] Sometimes a few cycles of chemotherapy are given, followed by radiation, and then chemotherapy is given again. This is called sandwich therapy. It may be used for some types of endometrial carcinoma such as papillary serous carcinoma and carcinosarcoma. […] Chemotherapy is given for different reasons. You may have chemotherapy or chemoradiation to: destroy cancer cells in the body, destroy cancer cells left behind after surgery and reduce the risk of the cancer recurring (called adjuvant chemotherapy), relieve pain or control the symptoms of advanced uterine cancer (called palliative chemotherapy).

• #1 Chemotherapy for uterine cancer | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/uterine/treatment/chemotherapy

  Chemotherapy is usually a systemic therapy. This means that the drugs travel through the bloodstream to reach and destroy cancer cells all over the body, including those that may have broken away from the primary tumour in the uterus. […] The types and combinations of chemotherapy drugs used vary depending on the type of tumour being treated. Usually 2 or more drugs are given in combination to treat uterine cancer. […] A common chemotherapy combination used to treat uterine sarcoma is docetaxel and gemcitabine. […] Side effects can happen with any type of treatment for uterine cancer, but everyone’s experience is different. Some people have many side effects. Other people have few or none at all. […] Chemotherapy may cause side effects because it can damage healthy cells as it kills cancer cells. Side effects can develop any time during, immediately after or a few days or weeks after chemotherapy. Sometimes late side effects develop months or years after chemotherapy. Most side effects go away on their own or can be treated, but some side effects may last a long time or become permanent.

• #1 Endometrial Cancer Treatment Protocols: Treatment Protocols

  https://emedicine.medscape.com/article/2001830-overview

  High-risk: Adjuvant therapy is recommended for all patients, including radiation therapy and chemotherapy. […] Combination therapy: Carboplatin AUC 5-7 IV and paclitaxel 175 mg/m2 IV on Day 1 q3wk or Carboplatin AUC 5-6 IV and paclitaxel 175 mg/m2 IV plus pembrolizumab 200 mg IV (for stage III-IV tumors, except for carcinosarcoma) on Day 1 q3wk x 6 cycles, followed by single-agent pembrolizumab 400 mg IV q6wk for up to 14 cycles. […] Preferred regimens: Carboplatin AUC 5-7 IV and paclitaxel 175 mg/m2 IV on Day 1 q3wk or Carboplatin AUC 5-6 IV and paclitaxel 175 mg/m2 IV plus pembrolizumab 200 mg IV (for stage III-IV tumors, except for carcinosarcoma) on Day 1 q3wk x 6 cycles, followed by single-agent pembrolizumab 400 mg IV q6wk for up to 14 cycles. […] Treatment options under clinical evaluation for advanced and recurrent endometrial cancer include the following: Paclitaxel and carboplatin with or without metformin in stages III, IV, and recurrent endometrial cancer.

• #1 Chemotherapy for uterine cancer | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/uterine/treatment/chemotherapy

  Side effects of chemotherapy will depend mainly on the type of drug, the dose, how it’s given and your overall health. Some common side effects of chemotherapy drugs used for uterine cancer are: low blood cell counts (called bone marrow suppression), nausea and vomiting, loss of appetite, sore mouth and throat, constipation, diarrhea, fatigue, hair loss, skin problems. […] Tell your healthcare team if you have these side effects or others you think might be from chemotherapy. The sooner you tell them of any problems, the sooner they can suggest ways to help you deal with them.

• #1 Treatments for uterine cancer | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/uterine/treatment

  If you have uterine cancer, your healthcare team will create a treatment plan just for you. It will be based on your health and specific information about the cancer. When deciding which treatments to offer for uterine cancer, your healthcare team will consider: […] Most women with uterine cancer will have surgery. The type of surgery depends mainly on the stage of the cancer and other factors. […] Radiation therapy uses high-energy rays or particles to destroy cancer cells. It is usually used to treat uterine cancer. Radiation therapy is sometimes combined with chemotherapy to treat some types of uterine cancer. […] Some women with uterine cancer have hormonal therapy. It is a treatment that adds, blocks or removes hormones. […] Chemotherapy uses anticancer, or cytotoxic, drugs to destroy cancer cells. It is sometimes used to treat uterine cancer.

• #1 Womb (uterus) cancer | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/cancer/cancer-types-in-adults/womb-uterus-cancer/

  Advanced womb cancer requires a different course of treatment, usually depending more on chemotherapy. […] Advanced cancer may not be curable, but the treatment aims to achieve a remission, where the cancer shrinks, making you feel normal and able to enjoy life to the full. […] Even if there’s no chance of a cure, surgery may be carried out to remove as much of the cancer as possible. […] Radiotherapy may also be used to slow the spread of cancer when a surgical cure is not possible. […] If you have stage 3 or 4 womb cancer, you may be given a course of chemotherapy. Chemotherapy can be used after surgery to try to prevent the return of the cancer. […] Some womb cancers are affected by the female hormone oestrogen. These cancers may respond to treatment with hormone therapy. […] Hormone therapy usually replaces a hormone called progesterone, which naturally occurs in your body. Artificial progesterone is used and is usually given as tablets.

• #1 5 Innovative Endometrial Cancer Treatment Options | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/endometrial-cancer/endometrial-cancer-treatment.html

  This therapy may be used to treat endometrial cancer after a hysterectomy or as the main treatment when surgery is not possible. […] MD Anderson provides the most advanced radiation treatments for endometrial cancer. […] Chemotherapy drugs kill cancer cells, control their growth or relieve disease-related symptoms. […] Hormone therapies that may be used to treat endometrial cancer include progestins, tamoxifen, and aromatase inhibitors. […] Targeted therapy drugs are designed to stop or slow the growth or spread of cancer. […] Immunotherapy improves the immune systems ability to eliminate cancer. […] Because of our status as one of the worlds premier cancer centers, MD Anderson participates in many clinical trials for endometrial cancer.

• #1 Uterine Sarcoma: Symptoms, Diagnosis, Treatment & Prevention

  https://my.clevelandclinic.org/health/diseases/16408-uterine-sarcoma

  Hormone therapy stops cancer growth by blocking the action of the hormones. Hormones, such as progestins, gonadotropin-releasing hormone agonists and aromatase inhibitors, are used in treating uterine sarcoma. […] Uterine sarcoma is curable, especially if it’s low-grade (mildly abnormal cells) and it hasn’t spread beyond your uterus. In some cases, additional treatment, like chemotherapy and radiation, may be needed to destroy the cancer cells completely.

• #1 Uterine cancer | Causes, Symptoms & Treatments | Cancer Council

  https://www.cancer.org.au/cancer-information/types-of-cancer/uterine-cancer

  For most women with uterine cancer, surgery will be the only treatment required, particularly if the cancer is diagnosed early and has not spread to other parts of the body. […] The most common form of treatment for cancer of the uterus is surgically removing the uterus and cervix. This procedure is called a total hysterectomy. If the fallopian tubes and both ovaries are also removed, it is called a bilateral salpingo-oophorectomy. […] Radiation therapy, the use of x-rays to kill or injure cancer cells, is commonly used as an additional treatment to reduce the chance of the cancer coming back. It may be recommended as the main treatment if you are not well enough for surgery. […] Hormone therapy is usually given if the cancer has spread or if the cancer has come back (recurred). It is also sometimes used if surgery is not an option.

• #1 Cancer Society NZ — Treatment of uterus cancer

  https://www.cancer.org.nz/cancer/types-of-cancer/uterus-cancer/treatment-of-uterus-cancer/

  Radiation treatment uses x-ray beams to kill cancer cells. Treatment is carefully planned to do as little harm to normal cells. […] Chemotherapy uses anti-cancer drugs to destroy the cancer cells while doing the least possible damage to normal cells. […] Chemotherapy is used to treat uterine cancer when: the cancer has returned after surgery or radiation, the cancer is not responding to hormone treatment. […] It may take some time to recover from uterine cancer treatment. […] The side effects may include: tiredness, premature menopause, bladder problems, bowel problems, lymphoedema. […] Palliative care aims to improve your quality of life. It is not just about end of life care. […] Speak with your treatment team about palliative care options for you and your family/whānau.

• #1 Uterine Cancer Treatment | Roswell Park Comprehensive Cancer Center – Buffalo, NY

  https://www.roswellpark.org/cancer/uterine-endometrial/treatment

  The treatment plan thats best for you will depend on several factors, including your general health, your cancers stage and grade, and any unique genetic mutation that may be present. While surgery is often the primary (first) treatment for uterine cancer, many patients also have radiation therapy, hormone therapy, and chemotherapy or immunotherapy drugs. […] Your treatment may include one or more of the following approaches: Surgery to remove the uterus, cervix and other tissues affected by the cancer. Radiation therapy to shrink tumors before surgery, kill cancer cells after surgery, prevent recurrence or relieve symptoms. Chemotherapy to kill cancer cells in the body before or after surgery. Hormone therapy to slow or stop tumor growth in tumors that are fueled by certain hormones. Targeted therapy to attack cancer cells by interfering with certain proteins or enzymes that the cancer cells need to grow. Immunotherapy to boost your own immune system to fight the cancer. Fertility sparing treatment which uses hormone therapy first, allowing time for childbearing before undergoing curative surgery. Clinical trials to access the very latest options.

• #1 Endometrial cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/endometrial-cancer/diagnosis-treatment/drc-20352466

  Targeted therapy uses medicines that attack specific chemicals in cancer cells. By blocking these chemicals, targeted treatments can cause cancer cells to die. Targeted therapy is usually combined with chemotherapy for treating advanced endometrial cancer. […] Immunotherapy uses medicine that helps the body’s immune system kill cancer cells. The immune system fights off diseases by attacking germs and other cells that shouldn’t be in the body. Cancer cells survive by hiding from the immune system. Immunotherapy helps the immune system cells find and kill the cancer cells. For endometrial cancer, immunotherapy might be considered if the cancer is advanced and other treatments haven’t helped. […] Palliative care is a special type of health care that helps you feel better when you have a serious illness. If you have cancer, palliative care can help relieve pain and other symptoms. Palliative care is done by a team of health care professionals. This can include doctors, nurses and other specially trained professionals. Their goal is to improve the quality of life for you and your family.

• #1 Uterine Cancer Treatment and Outlook

  https://www.healthline.com/health/cancer/uterine-cancer-treatment

  Radiation therapy uses high energy radiation to kill cancer cells. Like chemotherapy, it can be used at all stages of uterine cancer, such as: before surgery to help shrink the cancer, after surgery to help kill remaining cancer cells when there’s a higher risk of the cancer coming back, as a main part of treatment if you cannot or choose not to have surgery. […] Hormone therapy works by using hormones or drugs that block hormones to keep cancer from growing. […] Hormone therapy is often used to treat more advanced uterine cancer or cancer that’s come back. It may also be used alongside other treatments, such as chemotherapy or targeted therapy. […] Targeted therapy involves drugs that target certain markers found inside or on the surface of cancer cells. This type of treatment is typically used when uterine cancer is advanced or has recurred.

• #1 In-Treatment For Uterine Cancer | SHARE Cancer Support

  https://www.sharecancersupport.org/uterine-cancer/treatment/

  Immunotherapy helps your own immune system fight against cancer cells. […] The main immunotherapy drug used for endometrial cancer is pembrolizumab (Keytruda). […] Cancer that returns may be treated with chemotherapy to destroy the cancer and slow the tumors growth. Chemotherapy is the most common treatment for recurrent uterine cancer. […] Hormone therapy to slow the growth of certain types of uterine cancer cells that have receptors for estrogen on their surface. […] Immunotherapy that boosts the body’s natural defenses to fight the cancer.

• #1 Uterine Cancer Treatment Options, Types of Uterine Cancer Treatment

  https://iconcancercentre.com.au/treatment/uterine-cancer/

  Similar to immunotherapy, targeted therapies may be used to treat advanced and high-risk uterine cancers or uterine cancers that have returned. Targeted therapies focus specifically on treating the uterine cancer through targeting cancer cells and not healthy cells. […] When you are diagnosed with uterine cancer, your oncologist will develop your treatment plan as part of a multidisciplinary team based on the stage of your cancer and whether you would like to remain fertile after treatment. […] Common treatment options for each stage of uterine cancer include: […] Stage I uterine cancer is typically treated with a hysterectomy and bilateral salpingo-oophorectomy (removal of the uterus, fallopian tubes and both ovaries). In many cases, surgery is the only treatment needed for stage I uterine cancer. Surgery may be followed by chemotherapy and radiation therapy to prevent the cancer cells from coming back.

• #1 Radiation Therapy for Uterine Cancer | Nebraska Hematology Oncology – Cancer Care Treatment Blood Disorders Clinical Trials Lincoln Nebraska (NE)

  https://www.yourcancercare.com/types-of-cancer/uterine-cancer/radiation-therapy-for-uterine-cancer

  The delivery of cancer treatment following local treatment with surgery is referred to as adjuvant therapy and may include chemotherapy, radiation therapy, hormonal therapy and/or biologic therapy. […] Although it is still being evaluated in clinical trials, many patients with stage IB and IC uterine cancer are often treated with adjuvant radiation therapy. […] Brachytherapy treatment involves the placement of a radioactive isotope into the vagina and may have fewer side effects than external beam radiation. […] Treatment of stage II uterine cancer with surgery followed by adjuvant brachytherapy and external beam radiation therapy has been reported to cure 60-80% of patients. […] Patients with stage III uterine cancer who have complete surgical removal of all cancer are candidates for adjuvant radiation therapy.

• #1 Treatment Choices for Endometrial Cancer, by Stage | American Cancer Society

  https://www.cancer.org/cancer/types/endometrial-cancer/treating/by-stage.html

  If it doesnt go away in 6 to 12 months, surgery (hysterectomy and removal of both fallopian tubes and ovaries) to remove and stage the cancer is recommended. […] After surgery, chemotherapy (chemo) with or without radiation therapy is given to help keep the cancer from coming back. […] After surgery, radiation therapy, chemo, or both may be given to help keep the cancer from coming back. […] In many cases of stage IV endometrial cancer, the cancer has spread too far for it all to be removed with surgery. A hysterectomy and removal of both fallopian tubes and ovaries may still be done to prevent excessive bleeding. Radiation therapy may also be used for this reason. When the cancer has spread to other parts of the body, hormone therapy may be used. […] Combinations of chemo drugs may help some patients for a time. Targeted drugs and/or immunotherapy drugs may also be options for some with advanced endometrial cancer.

• #1 Treatment Choices for Endometrial Cancer, by Stage | American Cancer Society

  https://www.cancer.org/cancer/types/endometrial-cancer/treating/by-stage.html

  For local recurrences, such as in the pelvis, surgery (sometimes followed by radiation therapy) is used. For those with other medical conditions that make them unable to have surgery, radiation therapy alone or combined with hormone therapy tends to be used. […] Higher-grade cancers are unlikely to shrink with hormone therapy but may respond to chemo, targeted therapy and immunotherapy.

• #1 Uterine cancer | Causes, Symptoms & Treatments | Cancer Council

  https://www.cancer.org.au/cancer-information/types-of-cancer/uterine-cancer

  Chemotherapy is used to treat certain types of uterine cancer, or when cancer comes back after surgery or radiotherapy, or if the cancer is not responding to hormone treatment. […] Immunotherapy is a type of drug treatment that uses the body’s own immune system to fight cancer. […] Targeted therapy is a drug treatment that attacks specific features of cancer cells to stop the cancer growing and spreading. […] In some cases of uterine cancer, your medical team may talk to you about palliative care. Palliative care aims to improve your quality of life by alleviating symptoms of cancer.

• #1 Endometrial Cancer Treatment Landing Page | American Cancer Society | American Cancer Society

  https://www.cancer.org/cancer/types/endometrial-cancer/treating.html

  Its important to talk with your family and treatment team about all of your treatment options, as well as their possible side effects, so you make the choice that best fits your needs. […] Clinical trials are carefully controlled research studies that are done to get a closer look at promising new treatments or procedures. Clinical trials are one way to get state-of-the-art cancer treatment. […] You may hear about alternative or complementary methods to relieve symptoms or treat your cancer that your doctors havent mentioned. […] Be sure to talk to your cancer care team about any method you are thinking about using. […] Knowing all of your options and finding the resources you need will help you make informed decisions about your care. […] Whether or not you continue treatment, there are still things you can do to help maintain or improve your quality of life. […] People who have advanced cancer and who are expected to live less than 6 months may want to consider hospice care.

• #1

  https://winshipcancer.emory.edu/cancer-types-and-treatments/uterine-cancer/treatment.php

  This treatment involves the use of medication to attack cancer cells throughout the body. […] This type of treatment uses drugs to help your bodys immune system recognize and enhance its ability to attack cancer cells. […] Winships most promising research in treating uterine cancer is in personalized medicine and targeted therapies. […] For women who wish to preserve their fertility, certain types of uterine cancer may be treated with a hormone. […] In addition to providing treatment, patients are also evaluated for clinical trials to see if they would benefit from an innovative option. […] At Winship, we strive to deliver the most effective treatment while also minimizing side effects.

• #1 Endometrial Cancer Treatment (PDQ®) – NCI

  https://www.cancer.gov/types/uterine/hp/endometrial-treatment-pdq

  In general, patients with stage III or stage IV endometrial cancer are treated with surgery, followed by chemotherapy, radiation therapy, or both. […] Several randomized trials have confirmed improved survival when adjuvant chemotherapy is used instead of radiation therapy. […] Hormone therapy is indicated for patients who are not candidates for either surgery or radiation therapy. Progestational agents produce good antitumor responses in 15% to 30% of patients. […] The use of immunotherapy has been evaluated for the treatment of advanced and recurrent disease. […] These three studies demonstrate the activity and benefit of immunotherapy in the treatment of patients with advanced stage and recurrent endometrial cancer.

• #1 Treatments for uterine cancer | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/uterine/treatment

  Follow-up after treatment is an important part of cancer care. Follow-up for uterine cancer is often shared among the cancer specialists (gynecologist, radiation oncologist, medical oncologist and surgeon) and your family doctor. They will work with you to decide on follow-up care to meet your needs.

• #1 Treatment for Uterine Sarcoma | Fred Hutchinson Cancer Center

  https://www.fredhutch.org/en/diseases/uterine-sarcoma/treatment.html

  Your team at Fred Hutch offers long-term follow-up care for as long as you choose after your treatment for uterine sarcoma. Our patients find it reassuring to see the same team members who treated them experts in gynecologic cancers for their follow-up visits. This includes physicians as well as advanced registered nurse practitioners (ARNPs). […] Typically, people come for checkups, including pelvic exams, every three months for the first two years after treatment. Some patients choose to have all these follow-up visits at Fred Hutch; some alternate between coming to Fred Hutch and seeing their local primary gynecologist. […] People who reach the two-year mark without having a recurrence of their disease are less likely to have a recurrence and can be seen less often. From that point, we usually ask you to come in every six months for a checkup until you are five years out from your primary treatment. After five years, an annual checkup is all that we recommend, and we offer long-term follow-up for as long as you choose to come here through our Womens Wellness Clinic.

• #1 Treatment For Womb Cancer | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/womb-cancer/treatment

  Chemotherapy uses anti cancer (cytotoxic) drugs to destroy cancer cells. The drugs circulate throughout the body in the bloodstream. […] Radiotherapy uses high energy x-rays to kill womb cancer cells. You might have radiotherapy after surgery to reduce the risk of cancer coming back or to help control the symptoms of advanced cancer. You might also have internal radiotherapy (brachytherapy). […] You might have hormone therapy for advanced womb cancer or womb cancer that has come back. […] Targeted cancer drugs work by targeting the differences in cancer cells that help them to grow and survive. Other drugs help the immune system to attack cancer. They are called immunotherapies. […] After treatment for womb cancer, you have checkups at the hospital. You also have tests, including blood tests, x-rays and scans. […] Unfortunately, advanced womb cancer can’t usually be cured, but there are a number of ways to control symptoms.

• #1 Uterine cancer – Wikipedia

  https://en.wikipedia.org/wiki/Uterine_cancer

  Uterine cancer, also known as womb cancer, includes two types of cancer that develop from the tissues of the uterus. […] Treatment may include a combination of surgery, radiation therapy, chemotherapy, hormone therapy, and targeted therapy. […] For endometrial cancer, five main types of treatments are used, including surgery, radiation therapy, chemotherapy, hormone therapy, and targeted therapy. The most common treatment modality for endometrial cancer is surgery, whereby the uterus is removed via a total hysterectomy. […] As of 2021, treatment options for uterine sarcoma include surgery, radiation therapy, chemotherapy, and hormone therapy. […] Prognosis varies for the different types of endometrial cancer. Factors that influence prognosis across types of uterine cancer are age at diagnosis, the stage of the cancer, the grade of the cancer, histology, depth of invasion into the myometrium, and the presence of spread to nearby lymph nodes or other regions.

• #1 Can endometrial cancer be cured? | Prof Andreas Obermair » Professor Andreas Obermair

  https://www.obermair.info/latest-news/blog/can-endometrial-cancer-be-cured/

  Due to early detection and treatment, the prognosis of endometrial cancer is excellent for most patients. The chances of a cure depends largely on the type of endometrial cancer and the stage at which endometrial cancer is diagnosed. […] There is a high chance of a cure if endometrial cancer is diagnosed and treated when the disease is at an early stage. […] The key to successful endometrial cancer treatment is surgery by removing the uterus (hysterectomy). Surgery for endometrial cancer will typically remove the uterus, fallopian tubes and both the ovaries. Overall, surgeons are confident that there is a low likelihood of the cancer returning when it was confined to these organs. […] Patients with lymph nodes that contain cancer (stage 3 or 4) will need further postoperative treatment, such as radiotherapy, chemotherapy, or combinations of both. […] Like most types of cancer, the outcomes are better when endometrial cancer is found and treated early.

• #1 Radiation Therapy for Uterine Cancer | Nebraska Hematology Oncology – Cancer Care Treatment Blood Disorders Clinical Trials Lincoln Nebraska (NE)

  https://www.yourcancercare.com/types-of-cancer/uterine-cancer/radiation-therapy-for-uterine-cancer

  The objective of radiation therapy is to kill uterine cancer cells for a maximum probability of cure or palliation with a minimum of side effects. […] Radiation can also be directly placed in the area of the cancer (brachytherapy) or in the area where unseen cancer is suspected. […] Modern radiation therapy for uterine cancers is given via machines called linear accelerators, which produce high-energy external radiation beams that penetrate the tissues and deliver the radiation dose deep into the areas where the cancer resides. […] A typical course of radiation for uterine cancer would entail daily radiation treatments, Monday through Friday, for 3 to 5 weeks. […] The vast majority of patients are able to complete radiation therapy for uterine cancer without significant difficulty.

• #2 Uterine Cancer (Endometrial Cancer): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/16409-uterine-cancer

  Many women who have uterine cancer need their ovaries removed. But removing the ovaries means you’ll go through menopause if you haven’t already. […] Often, surgeons use a single procedure to diagnose, stage (describe severity) and treat uterine sarcoma. Treatment options are like those for endometrial cancer. You may have a hysterectomy, as well as a BSO to remove your ovaries and fallopian tubes. […] Fortunately, endometrial cancer is often diagnosed at an early stage. That’s because many people notice unusual bleeding and tell their healthcare providers. If cancer gets caught early and hasn’t spread to other organs, removing your uterus can cure it.

• #2

  https://www.nhs.uk/conditions/womb-cancer/treatment/

  Womb cancer is usually treatable when its found early. […] The treatment you have for womb cancer will depend on: the size of the cancer, where it is, if it has spread, your general health. […] It will usually include surgery, chemotherapy or radiotherapy. It may also include treatment with targeted medicines to treat the cancer. […] Surgery is often the main treatment for womb cancer. Especially if the cancer is found early. […] If the cancer has spread to other parts of your body, you may need to have a combination of surgery, radiation and chemotherapy to remove as much of the cancer as possible. […] Radiotherapy uses high-energy rays of radiation to kill cancer cells. […] You may have radiotherapy for womb cancer: as the main treatment if you cannot have surgery, if the cancer is large or has spread, after surgery to help stop the cancer coming back, sometimes with chemotherapy (chemoradiotherapy).

• #2 Uterine Cancer (Endometrial Cancer): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/16409-uterine-cancer

  Uterine cancer includes two types of cancer: endometrial cancer (more common) and uterine sarcoma (rare). Treatment often consists of a hysterectomy to remove your uterus. […] Most women with endometrial cancer need surgery. Your particular treatment plan depends on the type of cancer and your overall health. Other treatments you may have include: Chemotherapy, which uses powerful drugs to destroy cancer cells. Radiation therapy, which sends targeted radiation beams to destroy cancer cells. Hormone therapy, which gives hormones or blocks them to treat cancer. Immunotherapy, which helps your immune system fight cancer. Targeted therapy, which uses medications to target specific cancer cells to stop them from multiplying. […] Surgery is usually the primary treatment for endometrial cancer. You’ll most likely have a hysterectomy, with the surgeon removing your uterus and cervix.

• #2 Endometrial Cancer Treatment (PDQ®) – NCI

  https://www.cancer.gov/types/uterine/hp/endometrial-treatment-pdq

  Cancer of the endometrium is the most common gynecologic malignancy in the United States and accounts for 7% of all cancers in women. Most cases are diagnosed at an early stage and are amenable to treatment with surgery alone. […] However, patients with pathological features predictive of a high rate of relapse and patients with extrauterine spread at diagnosis have a high rate of relapse despite adjuvant therapy. The most common cause of death in patients with endometrial cancer is cardiovascular disease because of related metabolic risk factors. […] Patients with endometrial cancer who have localized disease are usually cured. Best results are obtained with one of two standard treatments: Hysterectomy with bilateral salpingo-oophorectomy. Hysterectomy with bilateral salpingo-oophorectomy and adjuvant radiation therapy (when deep invasion of the myometrial muscle [more than 50% of the myometrium] or grade 3 tumor with myometrial invasion is present).

• #2 Uterine Cancer: Diagnosis & Treatment | NewYork-Presbyterian

  https://www.nyp.org/cancer/gynecologic-cancer/uterine-cancer/treatment

  How is Uterine Cancer Treated? Treatment […] Your doctor will decide on a treatment plan based on your medical history, the severity of your disease, your lifestyle, and your preferences. If you are interested in having children in the future, your doctor will discuss your options with you to see if your treatment can preserve your fertility. Treatments for uterine cancer, such as endometrial cancer, include: Hysterectomy. Surgery to remove the uterus, and sometimes the fallopian tubes and ovaries is the most common treatment for uterine cancers. Our surgeons often perform this procedure using robotic and laparoscopic surgeries, minimally invasive approaches associated with smaller incisions, less postoperative discomfort, and a quicker return to normal activities. Your surgeon will also remove lymph nodes in the pelvis to see if they contain cancer cells; this process, called staging, will determine if you need treatment other than surgery.

• #2 Endometrial Cancer Treatment Protocols: Treatment Protocols

  https://emedicine.medscape.com/article/2001830-overview

  RT is directed at sites of known or suspected tumor involvement and may include external beam radiation therapy (EBRT), brachytherapy, or both. […] RT has proven to be effective and tolerated in patients who are not candidates for surgery and whose disease is limited to the uterus. […] Patients with suspected or gross cervical involvement who are candidates for surgery should be recommended for radical hysterectomy with bilateral salpingo-oophorectomy, cytology, and dissection of pelvic and para-aortic lymph nodes; inoperable patients should be treated with RT (75-80 Gy). […] Patients with extrauterine pelvic disease should be treated with radiation therapy and brachytherapy with or without surgery and chemotherapy. […] In patients who wish to preserve fertility, continuous progestin-based therapy with megestrol, medroxyprogesterone, or a levonorgestrel intrauterine device and surveillance with endometrial sampling every 3-6 months may be considered if all the following criteria are met: Well-differentiated (grade 1) endometrioid adenocarcinoma on dilation and curettage (DC) confirmed by expert pathology review.

• #2 Radiation Therapy for Endometrial Cancer | NYU Langone Health

  https://nyulangone.org/conditions/endometrial-cancer/treatments/radiation-therapy-for-endometrial-cancer

  Doctors at NYU Langone may use radiation therapy to treat women who have endometrial cancer that has spread beyond the uterus and those who are at risk of a recurrence. Radiation therapy is a treatment that uses high-energy beams or materials to destroy cancer cells. […] Radiation therapy is often used after surgery to destroy any remaining cancer cells and to prevent a recurrence. This therapy is also the main treatment for women with recurrent uterine cancer and for those who cannot have surgery due to health concerns. […] Our doctors may combine radiation therapy and chemotherapy drugs that destroy cancer cells to eliminate large tumors in the uterus or cancer that has spread to other areas of the body. This type of treatment is called chemoradiation. […] High-dose-rate brachytherapy may be used after surgery to kill remaining cancer cells and reduce the risk of recurrence. In this approach, doctors temporarily place a radioactive substance directly on the area where the cancer occurred or in the area where cancer may return.

• #2 Radiation Therapy for Cancer of the Uterus | Cancer Council NSW

  https://www.cancercouncil.com.au/uterine-cancer/treatment/radiotherapy/

  Radiation therapy for cancer of the uterus is commonly used as an additional treatment after surgery to reduce the chance of the disease coming back. This is called adjuvant therapy. […] In some cases, radiation therapy may be recommended as the main treatment (e.g. when other health conditions mean you are not well enough for a major operation). […] There are 2 main ways of delivering radiation therapy: internally and externally. […] Internal radiation therapy may be used after a hysterectomy to deliver radiation directly to the top of the vagina (vaginal vault) from inside your body. […] External beam radiation therapy (EBRT) directs the radiation at the cancer and surrounding tissue from outside the body. […] For cancer of the uterus, the lower abdomen and pelvis are treated, but if the cancer has spread (metastasised), other areas may also be treated. […] If you are having EBRT, you will probably have daily treatments, Monday to Friday, for 5–6 weeks as an outpatient. It’s very important that you attend all of your scheduled sessions to ensure you receive enough radiation to make the treatment effective.

• #2

  https://www.nhs.uk/conditions/womb-cancer/treatment/

  Chemotherapy is medicine that kills cancer cells. […] You may have chemotherapy for womb cancer: on its own, or with radiotherapy (chemoradiotherapy), as the main treatment for womb cancer if you cannot have surgery, after surgery (usually with radiotherapy) to help stop the cancer coming back, to help slow the cancer down and ease symptoms if it has spread to other parts of your body. […] You may have hormone therapy to ease symptoms or shrink and control the cancer if it has spread outside your womb to other parts in your body. […] This treatment is suitable if youre not well enough to have surgery or radiotherapy. […] Immunotherapy medicines help your immune system to find and kill cancer cells. […] This treatment may be suitable if you have advanced womb cancer or if womb cancer has come back after treatment.

• #2 Chemotherapy for uterine cancer | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/uterine/treatment/chemotherapy

  Chemotherapy uses anticancer, or cytotoxic, drugs to destroy cancer cells. It is sometimes used to treat uterine cancer. Your healthcare team will consider your personal needs to plan the drugs, doses and schedules of chemotherapy. You may also receive other treatments. […] Chemotherapy is sometimes combined with radiation therapy to treat some types of uterine cancer. This is called chemoradiation. The 2 treatments are given during the same time period. […] Sometimes a few cycles of chemotherapy are given, followed by radiation, and then chemotherapy is given again. This is called sandwich therapy. It may be used for some types of endometrial carcinoma such as papillary serous carcinoma and carcinosarcoma. […] Chemotherapy is given for different reasons. You may have chemotherapy or chemoradiation to: destroy cancer cells in the body, destroy cancer cells left behind after surgery and reduce the risk of the cancer recurring (called adjuvant chemotherapy), relieve pain or control the symptoms of advanced uterine cancer (called palliative chemotherapy).

• #2 Uterine cancer | Causes, Symptoms & Treatments | Cancer Council

  https://www.cancer.org.au/cancer-information/types-of-cancer/uterine-cancer

  Chemotherapy is used to treat certain types of uterine cancer, or when cancer comes back after surgery or radiotherapy, or if the cancer is not responding to hormone treatment. […] Immunotherapy is a type of drug treatment that uses the body’s own immune system to fight cancer. […] Targeted therapy is a drug treatment that attacks specific features of cancer cells to stop the cancer growing and spreading. […] In some cases of uterine cancer, your medical team may talk to you about palliative care. Palliative care aims to improve your quality of life by alleviating symptoms of cancer.

• #2 Uterine cancer | Causes, Symptoms & Treatments | Cancer Council

  https://www.cancer.org.au/cancer-information/types-of-cancer/uterine-cancer

  For most women with uterine cancer, surgery will be the only treatment required, particularly if the cancer is diagnosed early and has not spread to other parts of the body. […] The most common form of treatment for cancer of the uterus is surgically removing the uterus and cervix. This procedure is called a total hysterectomy. If the fallopian tubes and both ovaries are also removed, it is called a bilateral salpingo-oophorectomy. […] Radiation therapy, the use of x-rays to kill or injure cancer cells, is commonly used as an additional treatment to reduce the chance of the cancer coming back. It may be recommended as the main treatment if you are not well enough for surgery. […] Hormone therapy is usually given if the cancer has spread or if the cancer has come back (recurred). It is also sometimes used if surgery is not an option.

• #2 Endometrial Cancer Treatment (PDQ®) – NCI

  https://www.cancer.gov/types/uterine/hp/endometrial-treatment-pdq

  Patients with regional and distant metastases are rarely cured, although they are occasionally responsive to standard hormone therapy. […] Progestational agents have been evaluated as adjuvant therapy in several randomized trials. A meta-analysis by the Cochrane group confirms no clinical benefit to adjuvant progestogens in clinical stage I disease. […] The treatment options for each stage of endometrial cancer are presented in Table 11. […] Treatment of stage I and stage II endometrial cancer depends on the grade and histological type. […] Most patients do well with surgery alone. However, patients with stage I disease who have high-risk histologies are at a greater risk of recurrence and are eligible for adjuvant therapy. […] Treatment options for patients with stage III, stage IV, and recurrent endometrial cancer include: Surgery followed by chemotherapy or radiation therapy. Chemotherapy and radiation therapy. Hormone therapy. Biological therapy. Immunotherapy. Clinical trials.

• #2 Uterine Sarcoma: Symptoms, Diagnosis, Treatment & Prevention

  https://my.clevelandclinic.org/health/diseases/16408-uterine-sarcoma

  Hormone therapy stops cancer growth by blocking the action of the hormones. Hormones, such as progestins, gonadotropin-releasing hormone agonists and aromatase inhibitors, are used in treating uterine sarcoma. […] Uterine sarcoma is curable, especially if it’s low-grade (mildly abnormal cells) and it hasn’t spread beyond your uterus. In some cases, additional treatment, like chemotherapy and radiation, may be needed to destroy the cancer cells completely.

• #2 Endometrial Cancer Treatment Protocols: Treatment Protocols

  https://emedicine.medscape.com/article/2001830-overview

  High-risk: Adjuvant therapy is recommended for all patients, including radiation therapy and chemotherapy. […] Combination therapy: Carboplatin AUC 5-7 IV and paclitaxel 175 mg/m2 IV on Day 1 q3wk or Carboplatin AUC 5-6 IV and paclitaxel 175 mg/m2 IV plus pembrolizumab 200 mg IV (for stage III-IV tumors, except for carcinosarcoma) on Day 1 q3wk x 6 cycles, followed by single-agent pembrolizumab 400 mg IV q6wk for up to 14 cycles. […] Preferred regimens: Carboplatin AUC 5-7 IV and paclitaxel 175 mg/m2 IV on Day 1 q3wk or Carboplatin AUC 5-6 IV and paclitaxel 175 mg/m2 IV plus pembrolizumab 200 mg IV (for stage III-IV tumors, except for carcinosarcoma) on Day 1 q3wk x 6 cycles, followed by single-agent pembrolizumab 400 mg IV q6wk for up to 14 cycles. […] Treatment options under clinical evaluation for advanced and recurrent endometrial cancer include the following: Paclitaxel and carboplatin with or without metformin in stages III, IV, and recurrent endometrial cancer.

• #2 Radiation Therapy for Uterine Cancer | Nebraska Hematology Oncology – Cancer Care Treatment Blood Disorders Clinical Trials Lincoln Nebraska (NE)

  https://www.yourcancercare.com/types-of-cancer/uterine-cancer/radiation-therapy-for-uterine-cancer

  The delivery of cancer treatment following local treatment with surgery is referred to as adjuvant therapy and may include chemotherapy, radiation therapy, hormonal therapy and/or biologic therapy. […] Although it is still being evaluated in clinical trials, many patients with stage IB and IC uterine cancer are often treated with adjuvant radiation therapy. […] Brachytherapy treatment involves the placement of a radioactive isotope into the vagina and may have fewer side effects than external beam radiation. […] Treatment of stage II uterine cancer with surgery followed by adjuvant brachytherapy and external beam radiation therapy has been reported to cure 60-80% of patients. […] Patients with stage III uterine cancer who have complete surgical removal of all cancer are candidates for adjuvant radiation therapy.

Zobacz więcej