Hiperpotliwość
Diagnostyka i diagnoza
Hiperhidroza to stan nadmiernego wydzielania potu przekraczającego potrzeby termoregulacyjne, wymagający różnicowania na hiperhidrozę pierwotną i wtórną. Pierwotna hiperhidroza, zwykle rozpoczynająca się przed 25. rokiem życia, charakteryzuje się symetrycznym, ogniskowym poceniem, ustępującym podczas snu, natomiast wtórna jest związana z chorobami podstawowymi (np. nadczynność tarczycy, cukrzyca) i może mieć charakter uogólniony, także w nocy. Diagnostyka opiera się na szczegółowym wywiadzie (czas trwania objawów ≥6 miesięcy, lokalizacja, symetria, częstotliwość epizodów, wpływ na jakość życia) oraz badaniu przedmiotowym. Kryteria rozpoznania pierwotnej hiperhidrozy obejmują m.in. obustronne pocenie, występowanie co najmniej jednego epizodu tygodniowo, brak pocenia podczas snu oraz dodatni wywiad rodzinny. W diagnostyce pomocne są testy takie jak test Minora (jodowo-skrobiowy), grawimetria (wydzielanie potu >50 mg/min w pachach lub >20 mg/min na dłoniach) oraz testy oceniające funkcję nerwów autonomicznych.
- Diagnostyka hiperhidrozy (nadpotliwości)
- Rozróżnienie typów hiperhidrozy
- Wywiad medyczny i badanie przedmiotowe
- Kryteria diagnostyczne dla hiperhidrozy pierwotnej
- Testy diagnostyczne w hiperhidrozie
- Test skrobiowo-jodowy (Test Minora)
- Test grawimetryczny
- Termoregulacyjny test potowy (TST)
- Skale oceny nasilenia hiperhidrozy
- Badania laboratoryjne w diagnostyce różnicowej
- Znaczenie oceny jakości życia w diagnostyce hiperhidrozy
- Diagnostyka różnicowa hiperhidrozy
- Rola specjalistów w diagnostyce hiperhidrozy
- Podsumowanie procesu diagnostycznego
Diagnostyka hiperhidrozy (nadpotliwości)
Hiperhidrosis (hiperpotliwość) to stan charakteryzujący się nadmiernym wydzielaniem potu, które przekracza potrzeby termoregulacyjne organizmu. Diagnostyka tego schorzenia ma kluczowe znaczenie dla wdrożenia odpowiedniego leczenia i poprawy jakości życia pacjentów. Właściwa diagnoza pozwala również na rozróżnienie między pierwotną hiperhidrozą a wtórną, która jest objawem innej choroby podstawowej.12
Rozróżnienie typów hiperhidrozy
Pierwszym krokiem w diagnostyce nadpotliwości jest ustalenie, czy mamy do czynienia z hiperhidrozą pierwotną czy wtórną. Hiperhidroza pierwotna (idiopatyczna) jest stanem, w którym nadmierne pocenie się nie ma uchwytnej przyczyny medycznej. Najczęściej pojawia się przed 25 rokiem życia i charakteryzuje się symetrycznym, ogniskowym poceniem się, które ustępuje podczas snu.34
Natomiast hiperhidroza wtórna jest spowodowana innymi schorzeniami, takimi jak zaburzenia tarczycy, cukrzyca, zakażenia, zaburzenia neurologiczne lub jest efektem ubocznym przyjmowanych leków. W tym przypadku pocenie może być uogólnione i występować również podczas snu.56
Wywiad medyczny i badanie przedmiotowe
Diagnoza hiperhidrozy rozpoczyna się od dokładnego wywiadu medycznego. Lekarz zbiera informacje dotyczące:78
- Czasu trwania objawów nadmiernego pocenia się (co najmniej 6 miesięcy dla potwierdzenia hiperhidrozy pierwotnej)
- Lokalizacji nadmiernego pocenia (pachy, dłonie, stopy, twarz)
- Symetrii objawów (obustronne, symetryczne pocenie się sugeruje hiperhidrozę pierwotną)
- Częstotliwości epizodów (co najmniej jeden epizod tygodniowo)
- Czynników wyzwalających lub zaostrzających objawy
- Wpływu na codzienne aktywności i jakość życia
- Występowania objawów podczas snu (brak objawów podczas snu sugeruje hiperhidrozę pierwotną)
- Występowania hiperhidrozy w rodzinie (dodatni wywiad rodzinny przemawia za hiperhidrozą pierwotną)
Badanie przedmiotowe obejmuje ocenę wizualną obszarów dotkniętych nadmiernym poceniem się. Lekarz może szukać plam potu na ubraniu w celu oceny potliwości pachowej lub ocenić wilgotność dłoni podczas badania.1112
Kryteria diagnostyczne dla hiperhidrozy pierwotnej
Zgodnie z międzynarodowymi wytycznymi, diagnozę pierwotnej hiperhidrozy można postawić, gdy występuje ogniskowe, widoczne, nadmierne pocenie się trwające co najmniej 6 miesięcy bez uchwytnej przyczyny oraz gdy obecne są co najmniej dwa z poniższych kryteriów:1314
- Obustronne i symetryczne pocenie się
- Upośledzenie codziennych aktywności
- Występowanie co najmniej jednego epizodu tygodniowo
- Początek przed 25 rokiem życia
- Dodatni wywiad rodzinny
- Brak pocenia się podczas snu
Testy diagnostyczne w hiperhidrozie
W celu potwierdzenia diagnozy hiperhidrozy oraz oceny nasilenia i lokalizacji nadmiernego pocenia się, lekarze mogą stosować różne testy diagnostyczne.17
Test skrobiowo-jodowy (Test Minora)
Jest to prosty test pomagający zlokalizować obszary nadmiernego pocenia się. Przebieg badania wygląda następująco:1819
- Na suchą skórę nakłada się roztwór jodu (1-5%)
- Po wyschnięciu posypuje się obszar skrobią
- W miejscach intensywnego pocenia się skrobia reaguje z jodem, tworząc ciemnoniebieskie lub czarne zabarwienie
Test ten jest pomocny w identyfikacji dokładnych obszarów ciała, w których występuje nadmierna aktywność gruczołów potowych, co może być przydatne podczas planowania leczenia.22
Test grawimetryczny
Jest to ilościowa metoda pomiaru produkcji potu:2324
- Na badany obszar skóry nakłada się uprzednio zważony filtr papierowy
- Po określonym czasie (np. 5 minut) papier jest ponownie ważony
- Różnica wagi wskazuje ilość wydzielonego potu
Za wartości diagnostyczne dla hiperhidrozy uznaje się wydzielanie ponad 50 mg/min potu w okolicy pachowej lub ponad 20 mg/min na dłoniach.26
Termoregulacyjny test potowy (TST)
Ten test ocenia funkcjonowanie nerwów kontrolujących pocenie się:2728
- Pacjent jest umieszczany w pomieszczeniu o kontrolowanej temperaturze
- Na skórę nakłada się proszek wskaźnikowy zmieniający kolor
- Temperatura w pomieszczeniu jest stopniowo podnoszona
- Kiedy pacjent zaczyna się pocić, zmienia się pH skóry, co powoduje reakcję z proszkiem i jego zabarwienie
Test ten pozwala wykryć neuropatie drobnych włókien nerwowych w miejscach dotkniętych hiperhidrozą, potwierdzając diagnozę.30
Skale oceny nasilenia hiperhidrozy
Do oceny nasilenia hiperhidrozy i jej wpływu na jakość życia pacjenta stosuje się standaryzowane kwestionariusze i skale, takie jak:3132
- Hyperhidrosis Disease Severity Scale (HDSS) – prosta i najczęściej stosowana skala oceniająca tolerancję pocenia się i jego wpływ na jakość życia
- Dermatology Life Quality Index (DLQI) – kwestionariusz oceniający wpływ problemów skórnych na jakość życia
Wyniki tych ocen są pomocne w monitorowaniu skuteczności leczenia i doborze odpowiedniej metody terapeutycznej.35
Badania laboratoryjne w diagnostyce różnicowej
W przypadku podejrzenia hiperhidrozy wtórnej lub w celu wykluczenia innych przyczyn nadmiernego pocenia się, lekarz może zlecić dodatkowe badania laboratoryjne:3637
Podstawowe badania laboratoryjne
- Morfologia krwi – w celu wykluczenia infekcji, białaczki
- Parametry nerkowe i elektrolity
- Próby wątrobowe
- Poziom glukozy na czczo lub hemoglobina glikowana (HbA1c) – dla wykluczenia cukrzycy
- Hormony tarczycy (TSH, fT3, fT4) – dla wykluczenia nadczynności tarczycy
- Badanie ogólne moczu
Badania specjalistyczne
W wybranych przypadkach mogą być konieczne bardziej zaawansowane badania:40
- 24-godzinna zbiórka moczu na katecholaminy, metanefryny i normetanefryny – w kierunku guza chromochłonnego
- Oznaczenie kwasu 5-hydroksyindolooctowego w moczu – dla wykluczenia zespołu rakowiaka
- Testy w kierunku HIV
- Testy w kierunku gruźlicy
- OB i CRP – wskaźniki stanu zapalnego
- Badania obrazowe (RTG klatki piersiowej, TK) – w przypadku podejrzenia guza
Wybór badań diagnostycznych zależy od obrazu klinicznego i wywiadu zebranego od pacjenta. W przypadku charakterystycznego obrazu hiperhidrozy pierwotnej, przy braku objawów sugerujących chorobę podstawową, dodatkowe badania laboratoryjne mogą nie być konieczne.4344
Znaczenie oceny jakości życia w diagnostyce hiperhidrozy
Ocena wpływu hiperhidrozy na jakość życia pacjenta jest istotnym elementem procesu diagnostycznego. Nadmierne pocenie się może znacząco upośledzać funkcjonowanie społeczne, zawodowe i emocjonalne pacjentów.4546
Lekarze często pytają o wpływ nadmiernego pocenia się na:4748
- Codzienne aktywności
- Wybór ubrań
- Interakcje społeczne
- Uścisk dłoni i dotykanie innych osób
- Pracę zawodową i produktywność
- Stan emocjonalny (lęk, depresja, wstyd)
Informacje te pomagają w ocenie ciężkości schorzenia oraz w doborze odpowiedniego leczenia, zwłaszcza gdy dotknięty jest więcej niż jeden obszar ciała.51
Diagnostyka różnicowa hiperhidrozy
W procesie diagnostycznym hiperhidrozy należy uwzględnić inne stany, które mogą powodować podobne objawy:52
Stany wymagające różnicowania z hiperhidrozą
- Zaburzenia endokrynologiczne (nadczynność tarczycy, guz chromochłonny, akromegalia)
- Choroby infekcyjne (gruźlica, malaria, infekcje wirusowe)
- Zaburzenia metaboliczne (hipoglikemia)
- Nowotwory (białaczka, chłoniak, guz rakowiaka)
- Zaburzenia neurologiczne (uszkodzenie rdzenia kręgowego, dystrofia współczulna odruchowa)
- Zaburzenia psychiczne (lęk, stres)
- Efekty uboczne leków
Ważnym elementem różnicowania jest asymetria objawów – jednostronne, asymetryczne nadmierne pocenie się sugeruje przyczynę neurologiczną i wymaga dalszej diagnostyki.5556
Rola specjalistów w diagnostyce hiperhidrozy
W zależności od typu hiperhidrozy i jej nasilenia, w proces diagnostyczny mogą być zaangażowani różni specjaliści:5758
- Lekarz pierwszego kontaktu – wstępna diagnoza i skierowanie do odpowiedniego specjalisty
- Dermatolog – główny specjalista zajmujący się diagnozą i leczeniem hiperhidrozy
- Endokrynolog – diagnoza i leczenie zaburzeń hormonalnych, które mogą być przyczyną hiperhidrozy wtórnej
- Neurolog – ocena i leczenie przyczyn neurologicznych
- Chirurg ogólny lub torakochirurg – w przypadku kwalifikacji do leczenia operacyjnego (sympatektomia)
Diagnoza hiperhidrozy pierwotnej jest zwykle stawiana przez dermatologa na podstawie badania klinicznego i wywiadu, bez konieczności wykonywania specjalistycznych badań, o ile obraz kliniczny jest typowy.6162
Podsumowanie procesu diagnostycznego
Proces diagnostyczny hiperhidrozy można podsumować następująco:6364
- Zebranie dokładnego wywiadu medycznego
- Badanie przedmiotowe z oceną obszarów nadmiernego pocenia się
- Różnicowanie między hiperhidrozą pierwotną a wtórną
- Ocena nasilenia objawów i ich wpływu na jakość życia (skale HDSS, DLQI)
- W razie potrzeby wykonanie testów diagnostycznych potwierdzających nadmierne pocenie (test Minora, grawimetria)
- W przypadku podejrzenia hiperhidrozy wtórnej – zlecenie badań wykluczających choroby podstawowe
- Ustalenie ostatecznego rozpoznania i zaplanowanie leczenia
Właściwa diagnoza jest podstawą do wdrożenia skutecznego leczenia hiperhidrozy, które może obejmować leczenie miejscowe, doustne, iniekcje botuliny lub w niektórych przypadkach leczenie operacyjne.6768
Warto podkreślić, że hiperhidroza pozostaje często niedodiagnozowana ze względu na brak zgłaszania objawów przez pacjentów lub niedostateczną wiedzę na temat tego schorzenia wśród personelu medycznego. Dlatego tak ważna jest dokładna diagnostyka i świadomość tej jednostki chorobowej, która znacząco obniża jakość życia dotkniętych nią osób.6970
Kolejne rozdziały
Zapraszamy do dalszego czytania naszego leksykonu.
Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.
Materiały źródłowe
- #1 Hyperhidrosis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK459227/
Hyperhidrosis is a disorder of excessive sweating due to the overstimulation of cholinergic receptors on eccrine glands. This disorder is characterized by sweating beyond what the body uses for homeostatic temperature regulation. Eccrine glands are concentrated in areas such as the axillae, palms, soles, and face; therefore, these are most commonly associated with hyperhidrosis. […] The diagnosis is often made clinically, and grading scales and tests are available to determine the severity and localization. Laboratory workup may be indicated if a secondary cause is suspected to rule out infection, hyperthyroidism, diabetes mellitus, neurologic disorder, or a medication side-effect. […] Diagnosis is usually made from clinical assessment; thus, a visual inspection of the common sites is recommended. There are visual scales available to quantify the severity of palmar sweat. When localization is in question, an iodine-starch test can help localize the areas of concern, which is also beneficial during treatment.
- #2 The etiology, diagnosis, and management of hyperhidrosis: A comprehensive review: Etiology and clinical work-up – PubMedhttps://pubmed.ncbi.nlm.nih.gov/30710604/
Hyperhidrosis (HH) is a dermatologic disorder defined by sweat production exceeding thermoregulatory needs. Clinically, HH is diagnosed when excess sweating creates significant emotional, physical, or social discomfort, causing a negative impact on the patient’s quality of life. […] Secondary causes of HH need to be excluded before diagnosing primary HH.
- #3 Hyperhidrosis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK459227/
Diagnostic criteria for primary hyperhidrosis: Excessive sweating for 6 or more months, Sweating involves the axilla, palms, soles, and/or face, Sweating is bilateral and symmetric, Decreased or no sweating at night, Sweating episodes last at least 7 days, The individual is 25 years of age or younger, There is a family history, Sweating impairs daily living activities. […] If a secondary cause is suspected, providers should consider ordering a complete blood count, basic metabolic panel, thyroid-stimulating hormone, sedimentation rate, antinuclear antibody, hemoglobin A1C, and chest x-ray. These tests assist in ruling out infection, kidney dysfunction, malignancy, diabetes mellitus, thyroid disease, an inflammatory disorder, or connective tissue disease, which can all be associated with hyperhidrosis.
- #4 Diagnosis Guidelines – International Hyperhidrosis Society | Official Sitehttps://www.sweathelp.org/about-hyperhidrosis/diagnosis-guidelines.html
In summary, although the Hh diagnosis can usually be made on the basis of history and observed excessive sweating, gravimetric measurement may also provide a quantitative assessment. […] Given the potential for overlap in sweating rates between patients with hyperhidrosis and healthy controls, it is important to gauge the severity of social embarrassment and the effects on quality of life and impairment of daily activities in order to plan treatment, especially if more than one area is involved. […] The first step in the evaluation of a patient’s excessive sweating is to distinguish between primary and secondary hyperhidrosis. […] After this has been done, a diagnosis of primary (or idiopathic) Hh can be solidified using the ABCs, below. […] For a primary Hh diagnosis, look for excessive sweating symptoms or episodes (2 or more per week) that started 6+ months ago and appear to be chronic. […] Primary Hh does not cause excessive sweating during sleep.
- #5 Hyperhidrosis Diagnosis & Treatments | Mount Sinai – New Yorkhttps://www.mountsinai.org/care/thoracic-surgery/services/hyperhidrosis
You may find that you sweat a lot. All the time. You may find that you donât feel comfortable doing things other people take for granted, such as wearing nice clothes, shaking hands, or even gripping objects. Doctors call this condition hyperhidrosis. It affects approximately 7.8 million people in the United States. It commonly occurs in young adults, but may develop as early as childhood and persist throughout adult life. […] We make every effort to identify the underlying cause of hyperhidrosis before beginning treatment. You can have hyperhidrosis on one side of your body or on both (called bilateral). […] Sometimes hyperhidrosis is the main condition (primary) you are experiencing. Sometimes it is a side effect of another condition (secondary). Doctors do not know what causes primary hyperhidrosis. It is not very common, affecting about one percent of the population. Secondary hyperhidrosis can arise due to medical conditions such as:
- #6 Hyperhidrosis – Symptoms and causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/hyperhidrosis/symptoms-causes/syc-20367152
Hyperhidrosis treatment usually helps. […] See your health care provider if: […] Primary hyperhidrosis is caused by faulty nerve signals that trigger eccrine sweat glands to become overactive. […] There is no medical cause for this type of hyperhidrosis. […] Secondary hyperhidrosis is caused by an underlying medical condition or by taking certain medications, such as pain relievers, antidepressants, and some diabetes and hormonal medications. […] Complications of hyperhidrosis include: […] Hyperhidrosis care at Mayo Clinic […] Diagnosis treatment.
- #7 Hyperhidrosis – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/hyperhidrosis/diagnosis-treatment/drc-20367173
Diagnosing hyperhidrosis may start with your health care provider asking about your medical history and symptoms. You may also need a physical exam or tests to further evaluate the cause of your symptoms. […] Your health care provider may recommend blood, urine or other lab tests to see if your sweating is caused by another medical condition, such as an overactive thyroid (hyperthyroidism) or low blood sugar (hypoglycemia). […] Or you may need a test that pinpoints the areas of sweating and evaluates how severe your condition is. Two such tests are an iodine-starch test and a sweat test. […] Your health care provider is likely to ask you several questions, such as: When did the heavy sweating begin? Where on your body does it occur? Have your symptoms been continuous or occasional? What, if anything, seems to improve your symptoms? What, if anything, appears to worsen your symptoms?
- #8 Hyperhidrosis – Diagnosis & Treatmenthttps://www.upmc.com/services/esophageal-lung-surgery-institute/conditions/hyperhidrosis
Doctors in UPMC’s Division of Thoracic and Foregut Surgery can diagnose hyperhidrosis by observing the visible signs of unprovoked and excessive sweating. […] They may ask you details about your sweating, such as: Location on body, Time of occurrence, Onset (i.e. with or without warning), Triggers (i.e. thought process when sweating occurs), Other noticeable symptoms (i.e. heart pounding or weight loss).
- #9 Hyperhidrosis: Management Options | AAFPhttps://www.aafp.org/pubs/afp/issues/2018/0601/p729.html
Hyperhidrosis is excessive sweating that affects patients’ quality of life, resulting in social and work impairment and emotional distress. Primary hyperhidrosis is bilaterally symmetric, focal, excessive sweating of the axillae, palms, soles, or craniofacial region not caused by other underlying conditions. Secondary hyperhidrosis may be focal or generalized, and is caused by an underlying medical condition or medication use. The Hyperhidrosis Disease Severity Scale is a validated survey used to grade the tolerability of sweating and its impact on quality of life. The score can be used to guide treatment. […] There are no controlled studies on the sensitivity and specificity of the history, physical examination, or testing to accurately diagnose primary hyperhidrosis or to quantify its severity. Criteria for diagnosis include focal, visible, and excessive sweating for longer than six months without apparent cause, and at least two of the following: bilateral and symmetric sweating, impairment of daily activities, occurrence at least once per week, age of onset younger than 25 years, no occurrence during sleep, and a positive family history.
- #10 Hyperhidrosis and bromhidrosis A guide to assessment and managementhttps://www.racgp.org.au/afp/2013/may/hyperhidrosis-and-bromhidrosis
A diagnosis of idiopathic focal hyperhidrosis can be made on history if the patient is noted to have excessive visible sweating for at least 6 months and two of the following: bilateral symmetrical sweating, impairment of daily activities, at least one episode per week, onset before 25 years of age, positive family history, focal sweating that ceases during sleep. […] If there is no obvious underlying cause on history and examination, and the presentation is characteristic for primary focal hyperhidrosis, then further investigations are not required.
- #11 How Hyperhidrosis Is Diagnosedhttps://www.verywellhealth.com/hyperhidrosis-diagnosis-4778629
Diagnosing hyperhidrosis may be a very complex, or it may be a simple process, depending on the underlying cause. […] For example, if a person is diagnosed with primary focal hyperhidrosis, the diagnostic criteria are relatively straight forward and simple. […] But either way, the initial appointment will involve a physical exam, medical history, and some basic tests to determine if a person has hyperhidrosis. […] The answers to the questionnaire will provide a clue as to just how symptoms are impacting your daily life and activities. […] Your answers will be helpful for the healthcare provider in assessing how sweating affects your overall quality of life, daily activities, as well as your psychological and social well being. […] During the initial consultation, a healthcare provider will perform a physical exam and gather information on your health history.
- #12 How Hyperhidrosis Is Diagnosedhttps://www.verywellhealth.com/hyperhidrosis-diagnosis-4778629
The exam will include taking a very close look at the areas of the body where excessive sweating occurs. […] The diagnosing physician may look for stains on clothing to assess axillary (under the armpit) sweating. […] For diagnosing palmar (on the hand) hyperhidrosis, your healthcare provider may evaluate the severity of moisture on your hands during the physical exam. […] Diagnostic tests for hyperhidrosis focus on sweat tests. […] This test is helpful in diagnosing hyperhidrosis, particularly for detecting focal hyperhidrosis. […] This diagnostic test is used to measure the nerves that control sweating. […] Other tests that may be employed to measure the amount of sweat a person is experiencing including the use of gravimetry. […] The amount of sweat released at each time interval is measured and expressed as milligrams (mg)/time.
- #13 Hyperhidrosis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK459227/
Diagnostic criteria for primary hyperhidrosis: Excessive sweating for 6 or more months, Sweating involves the axilla, palms, soles, and/or face, Sweating is bilateral and symmetric, Decreased or no sweating at night, Sweating episodes last at least 7 days, The individual is 25 years of age or younger, There is a family history, Sweating impairs daily living activities. […] If a secondary cause is suspected, providers should consider ordering a complete blood count, basic metabolic panel, thyroid-stimulating hormone, sedimentation rate, antinuclear antibody, hemoglobin A1C, and chest x-ray. These tests assist in ruling out infection, kidney dysfunction, malignancy, diabetes mellitus, thyroid disease, an inflammatory disorder, or connective tissue disease, which can all be associated with hyperhidrosis.
- #14 Hyperhidrosis: Management Options | AAFPhttps://www.aafp.org/pubs/afp/issues/2018/0601/p729.html
Hyperhidrosis is excessive sweating that affects patients’ quality of life, resulting in social and work impairment and emotional distress. Primary hyperhidrosis is bilaterally symmetric, focal, excessive sweating of the axillae, palms, soles, or craniofacial region not caused by other underlying conditions. Secondary hyperhidrosis may be focal or generalized, and is caused by an underlying medical condition or medication use. The Hyperhidrosis Disease Severity Scale is a validated survey used to grade the tolerability of sweating and its impact on quality of life. The score can be used to guide treatment. […] There are no controlled studies on the sensitivity and specificity of the history, physical examination, or testing to accurately diagnose primary hyperhidrosis or to quantify its severity. Criteria for diagnosis include focal, visible, and excessive sweating for longer than six months without apparent cause, and at least two of the following: bilateral and symmetric sweating, impairment of daily activities, occurrence at least once per week, age of onset younger than 25 years, no occurrence during sleep, and a positive family history.
- #15 Hyperhidrosis and bromhidrosis A guide to assessment and managementhttps://www.racgp.org.au/afp/2013/may/hyperhidrosis-and-bromhidrosis
A diagnosis of idiopathic focal hyperhidrosis can be made on history if the patient is noted to have excessive visible sweating for at least 6 months and two of the following: bilateral symmetrical sweating, impairment of daily activities, at least one episode per week, onset before 25 years of age, positive family history, focal sweating that ceases during sleep. […] If there is no obvious underlying cause on history and examination, and the presentation is characteristic for primary focal hyperhidrosis, then further investigations are not required.
- #16 Hyperhidrosis (Excessive Sweating) | Doctorhttps://patient.info/doctor/hyperhidrosis
Diagnosing hyperhidrosis (investigations) If the presentation is characteristic of primary focal hyperhidrosis and there is no evidence of an underlying cause, no laboratory tests are required. Any initial investigations will often depend on individual context of patient and the history and examination but often include: FBC; blood film for malarial parasites may be indicated. ESR and/or CRP. Renal function tests and electrolytes. LFTs. Fasting blood glucose. TFTs. HIV testing. Tuberculosis testing 24 hour urinary collection for catecholamines, metanephrines (to exclude phaeochromocytoma), 5-hydroxyindoleacetic acid (to exclude carcinoid tumours). CXR. […] Diagnose primary focal hyperhidrosis when focal, visible, excessive sweating: Occurs in at least one of the following sites: axillae, palms, soles, or craniofacial region; and Has lasted at least six months; and Has no apparent cause; and Has at least two of the following characteristics: Bilateral and relatively symmetrical. Impairs daily activities. Frequency of at least one episode per week. Onset before 25 years of age. Positive family history. Cessation of local sweating during sleep. […] If symptoms have lasted less than six months or onset is at 25 years of age or older, primary focal hyperhidrosis remains a likely diagnosis if other criteria are met, but extra care should be taken to exclude an underlying cause.
- #17 Hyperhidrosis – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/hyperhidrosis/diagnosis-treatment/drc-20367173
Diagnosing hyperhidrosis may start with your health care provider asking about your medical history and symptoms. You may also need a physical exam or tests to further evaluate the cause of your symptoms. […] Your health care provider may recommend blood, urine or other lab tests to see if your sweating is caused by another medical condition, such as an overactive thyroid (hyperthyroidism) or low blood sugar (hypoglycemia). […] Or you may need a test that pinpoints the areas of sweating and evaluates how severe your condition is. Two such tests are an iodine-starch test and a sweat test. […] Your health care provider is likely to ask you several questions, such as: When did the heavy sweating begin? Where on your body does it occur? Have your symptoms been continuous or occasional? What, if anything, seems to improve your symptoms? What, if anything, appears to worsen your symptoms?
- #18 Hyperhidrosis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK459227/
Hyperhidrosis is a disorder of excessive sweating due to the overstimulation of cholinergic receptors on eccrine glands. This disorder is characterized by sweating beyond what the body uses for homeostatic temperature regulation. Eccrine glands are concentrated in areas such as the axillae, palms, soles, and face; therefore, these are most commonly associated with hyperhidrosis. […] The diagnosis is often made clinically, and grading scales and tests are available to determine the severity and localization. Laboratory workup may be indicated if a secondary cause is suspected to rule out infection, hyperthyroidism, diabetes mellitus, neurologic disorder, or a medication side-effect. […] Diagnosis is usually made from clinical assessment; thus, a visual inspection of the common sites is recommended. There are visual scales available to quantify the severity of palmar sweat. When localization is in question, an iodine-starch test can help localize the areas of concern, which is also beneficial during treatment.
- #19https://www.advancedfootclinic.org/understanding-hyperhidrosis-types-diagnoses-and-treatment-options
Patients with severe sweating may visit a doctor’s office for medical evaluation. Usually, doctors rely on one or more of the following tests to diagnose the condition. […] Your podiatrist may request sweat tests to assess the specific sweat sites and condition severity. A common sweat test entails the iodine starch test. The doctor applies iodine solution to your feet and allows them to dry. They then apply starch on your feet’s surface and observe the results. Blue-black patches form on the parts of your feet with excess sweating. The test facilitates targeted treatment. […] Some clinics use thermoregulatory sweat tests as a more reliable way to diagnose hyperhidrosis. The test detects small-fiber neuropathy in the affected sweat sites confirming hyperhidrosis. Doctors may then prescribe treatment or recommend specialized procedures to mitigate excess sweating.
- #20 How Hyperhidrosis Is Diagnosedhttps://www.verywellhealth.com/hyperhidrosis-diagnosis-4778629
A value of over 50 mg/min in the axillary (armpit) area, or more than 20 mg/min on the palms, indicates a diagnosis of hyperhidrosis. […] When the diagnosis of hyperhidrosis is secondary generalized hyperhidrosis, the diagnosing physician may need to perform several other tests to discover the primary (underlying) cause of sweating. […] The most common form of hyperhidrosis, involves sweating in one or more focal areas of the body, the most common areas that primary focal hyperhidrosis occurs is on the palms of the hands, under the arms and the soles of the feet. […] The diagnostic criteria (signs and symptoms that must be present to diagnosis a specific disease) for primary focal hyperhidrosis includes excessive sweating which occurs for six months or more in duration, along with four or more of the following:
- #21https://duradry.com/blogs/hyperhidrosis/how-do-doctors-diagnose-hyperhidrosis?srsltid=AfmBOooo6aYRNPiWKWMjX_hB6LzhNpUnffeisRfZ-V0l0_fLSEqC3nOP
Besides or in addition to blood tests, doctors can perform a host of other tests as well to help reach or reinforce a diagnosis. Focal hyperhidrosis doesn’t have an agreed-upon clinical threshold. There’s no set number all or even most doctors agree upon as being „too much” sweat. However, a normal baseline measurement at room temperature and at rest is 1 mL per square meter. Anything more than that is generally considered excessive. […] Another common measurement is a starch iodine test. A solution of 1 percent to 5 percent iodine is applied to a dry area suspected of excessive sweating. Starch is then sprinkled over the area. When you sweat, the iodine and starch interact and turn a dark purple color, thereby showing exactly where the problematic sweat gland ducts are. […] Thermoregulatory sweat testing, or TST, works much the same way. Patients are placed in a temperature-controlled room. A color-changing indicator powder is placed on the skin. The temperature in the room is gradually raised. As the patient starts to sweat, their skin pH changes and interacts with the powder, turning it into a dye that temporarily stains the skin. […] As you can see, determining why exactly hyperhidrosis occurs is not a perfect science, but there are tests available to help put you on the path toward symptom management.
- #22 BEAT THE SWEAT – Diagnosishttps://www.beatthesweat-mea.com/en/diagnosis
Severe primary axillary hyperhidrosis (underarm sweating) is usually diagnosed when a person has experienced at least 6 months of excessive underarm sweating (with no known cause) and also has at least two other characteristics listed below:1 […] You may need one or more tests to help pinpoint whats causing your body to sweat too much. Blood or urine tests may confirm or rule out an underlying medical condition. Your doctor also may recommend a test to measure how much sweat your body produces. […] Your doctor applies an iodine solution to the sweaty area and sprinkles starch over the iodine solution. Where you have excess sweating, the solution turns dark blue.2 […] Your doctor places special paper on the affected area to absorb sweat. Later, your doctor weighs the paper to determine how much you have sweated.2
- #23 How Hyperhidrosis Is Diagnosedhttps://www.verywellhealth.com/hyperhidrosis-diagnosis-4778629
The exam will include taking a very close look at the areas of the body where excessive sweating occurs. […] The diagnosing physician may look for stains on clothing to assess axillary (under the armpit) sweating. […] For diagnosing palmar (on the hand) hyperhidrosis, your healthcare provider may evaluate the severity of moisture on your hands during the physical exam. […] Diagnostic tests for hyperhidrosis focus on sweat tests. […] This test is helpful in diagnosing hyperhidrosis, particularly for detecting focal hyperhidrosis. […] This diagnostic test is used to measure the nerves that control sweating. […] Other tests that may be employed to measure the amount of sweat a person is experiencing including the use of gravimetry. […] The amount of sweat released at each time interval is measured and expressed as milligrams (mg)/time.
- #24 When to See a Hyperhidrosis Specialist: Diagnosis & Treatment | NY Metro Veinhttps://www.nymetrovein.com/blog/diagnosis-treatment-and-when-to-see-a-hyperhidrosis-specialist/
If you suspect you have this condition, the first step is to turn to a doctor who specializes in hyperhidrosis to get an official diagnosis. […] One type of test for hyperhidrosis is an iodine-starch test. The specialist will apply an iodine solution to the area where you sweat excessively and spread starch over it. If the solution turns dark blue, then you have hyperhidrosis. […] Another test is the paper test. Your doctor will place a special paper over the targeted areas and then weigh that paper to see how much you sweat. […] The specialist can also turn to blood and imaging tests to see if the condition has underlying causes, like hypoglycemia or hyperthyroidism.
- #25 SciELO Brazil – Palmar hyperhidrosis: clinical, pathophysiological, diagnostic and therapeutic aspects Palmar hyperhidrosis: clinical, pathophysiological, diagnostic and therapeutic aspectshttps://www.scielo.br/j/abd/a/wWFVwn5VLVswDWrMpzMrscw/
Palmar hyperhidrosis affects up to 3% of the population and inflict significant impact on quality of life. […] In this study, the authors discuss clinical findings, pathophysiological, diagnostic and therapeutic issues (clinical and surgical) related to palmar hyperhidrosis. […] The PH diagnosis is eminently clinical, being conducted through history and physical examination. Individuals with palmar hyperhidrosis present cold and wet hands with color that can ranges from pale to blush. […] The main diagnostic criteria include visible sweat, exaggerated and located, lasting at least six months, without apparent cause, and with at least two of the following characteristics: […] PH can be evidenced from the Minor test (starch-iodine), in which an alcoholic solution of iodine 2% is applied in the test area and subsequently starch (e.g. cornstarch) is sprinkled. […] For research purposes, the absorptiometry of sweating can be measured by paper filter technique and gravimetry. However, these techniques are difficult to reproduce in clinical practice because they need to be performed in an environment with controlled pressure and temperature.
- #26 How Hyperhidrosis Is Diagnosedhttps://www.verywellhealth.com/hyperhidrosis-diagnosis-4778629
A value of over 50 mg/min in the axillary (armpit) area, or more than 20 mg/min on the palms, indicates a diagnosis of hyperhidrosis. […] When the diagnosis of hyperhidrosis is secondary generalized hyperhidrosis, the diagnosing physician may need to perform several other tests to discover the primary (underlying) cause of sweating. […] The most common form of hyperhidrosis, involves sweating in one or more focal areas of the body, the most common areas that primary focal hyperhidrosis occurs is on the palms of the hands, under the arms and the soles of the feet. […] The diagnostic criteria (signs and symptoms that must be present to diagnosis a specific disease) for primary focal hyperhidrosis includes excessive sweating which occurs for six months or more in duration, along with four or more of the following:
- #27https://www.advancedfootclinic.org/understanding-hyperhidrosis-types-diagnoses-and-treatment-options
Patients with severe sweating may visit a doctor’s office for medical evaluation. Usually, doctors rely on one or more of the following tests to diagnose the condition. […] Your podiatrist may request sweat tests to assess the specific sweat sites and condition severity. A common sweat test entails the iodine starch test. The doctor applies iodine solution to your feet and allows them to dry. They then apply starch on your feet’s surface and observe the results. Blue-black patches form on the parts of your feet with excess sweating. The test facilitates targeted treatment. […] Some clinics use thermoregulatory sweat tests as a more reliable way to diagnose hyperhidrosis. The test detects small-fiber neuropathy in the affected sweat sites confirming hyperhidrosis. Doctors may then prescribe treatment or recommend specialized procedures to mitigate excess sweating.
- #28https://duradry.com/blogs/hyperhidrosis/how-do-doctors-diagnose-hyperhidrosis?srsltid=AfmBOooo6aYRNPiWKWMjX_hB6LzhNpUnffeisRfZ-V0l0_fLSEqC3nOP
Besides or in addition to blood tests, doctors can perform a host of other tests as well to help reach or reinforce a diagnosis. Focal hyperhidrosis doesn’t have an agreed-upon clinical threshold. There’s no set number all or even most doctors agree upon as being „too much” sweat. However, a normal baseline measurement at room temperature and at rest is 1 mL per square meter. Anything more than that is generally considered excessive. […] Another common measurement is a starch iodine test. A solution of 1 percent to 5 percent iodine is applied to a dry area suspected of excessive sweating. Starch is then sprinkled over the area. When you sweat, the iodine and starch interact and turn a dark purple color, thereby showing exactly where the problematic sweat gland ducts are. […] Thermoregulatory sweat testing, or TST, works much the same way. Patients are placed in a temperature-controlled room. A color-changing indicator powder is placed on the skin. The temperature in the room is gradually raised. As the patient starts to sweat, their skin pH changes and interacts with the powder, turning it into a dye that temporarily stains the skin. […] As you can see, determining why exactly hyperhidrosis occurs is not a perfect science, but there are tests available to help put you on the path toward symptom management.
- #29https://umiamihealth.org/en/treatments-and-services/dermatology/excessive-sweating-(hyperhidrosis)
If you experience excessive sweating when youre not exercising or somewhere with a high temperature, you may be suffering from hyperhidrosis. […] Through a medical examination of your skin, we can accurately diagnose and determine the best way to treat your hyperhidrosis. […] Your dermatologist may order a blood or urine test to make sure your hyperhidrosis isnt being caused by an underlying health condition, such as an overactive thyroid or low blood sugar. […] Your dermatologist may use a sweat test such as an iodine-starch test, thermoregulatory sweat test, or a skin conductance test to pinpoint the areas of sweating and determine the severity of your hyperhidrosis.
- #30 What Doctor Should You See For Hyperhidrosis? – Thompson Teehttps://thompsontee.com/blog/should-you-see-a-hyperhidrosis-doctor/?srsltid=AfmBOooQQX0JCmngOM3L2qZG9THxIIqm8EV-SIaqO95mcBRZsjbpryp_
If over-the-counter antiperspirants and prescription options dont work, your doctor may refer you to a dermatologist. […] Some clinics in the U.S. are devoted to the treatment and management of hyperhidrosis. […] If you have severe hyperhidrosis, your dermatologist may refer you to a neurologist. […] Surgery for hyperhidrosis should be a last resort. […] The International Hyperhidrosis Society is an independent, non-profit advocacy group supporting meaningful improvements in hyperhidrosis diagnosis, care and understanding. […] To find the right treatment, your doctor will ask for details about your sweating. […] Depending on the severity of your sweating, your doctor may also order tests. […] Your doctor may order blood tests to check for secondary hyperhidrosis, excessive sweating caused by another medical condition.
- #31 Diagnosis and qualitative identification of hyperhidrosis – Nawrocki – Shanghai Chesthttps://shc.amegroups.org/article/view/5191/html
Hyperhidrosis is a dermatologic disease defined as excessive sweating that exceeds thermoregulatory needs, and is estimated to affect at least 4.8% of the population. […] The diagnosis is partially determined and supported by objective quantitative tools, but is mainly identified by subjective accounts of patients regarding the extent of impact the excessive sweating has on their daily and general quality of life. […] Early diagnosis and proper treatment of PFHH are essential for minimizing its emotional, psychosocial, and physical effects. […] PFHH has distinguishable characteristics, allowing its diagnosis to be made solely on the medical history and physical examination. […] After establishing a diagnosis of PFHH, severity is determined. […] Various quantitative and qualitative methods are available to establish a diagnosis of HH, its severity, and the effect the condition has on a patients QoL.
- #32 Diagnosis and qualitative identification of hyperhidrosis – Nawrocki – Shanghai Chesthttps://shc.amegroups.org/article/view/5191/html
HH is commonly determined in qualitative terms. […] The scoring systems used in questionnaires are subjective, reflecting a bias in data collection. […] Impact on QoL has evolved to be the most valuable and essential evaluation modality for PFHH. […] The Hyperhidrosis Disease Severity Scale (HDSS) is disease-specific, simple, and the most commonly used method for measuring QoL in HH patients. […] Although the diagnosis of HH is commonly based on subjective testimonies from HH patients, various quantitative and qualitative measurement tools are available to identify the disease, grade its severity, and provide appropriate and prompt treatment.
- #33 Hyperhidrosis: Management Options | AAFPhttps://www.aafp.org/pubs/afp/issues/2018/0601/p729.html
Hyperhidrosis negatively impacts daily life, especially emotional well-being, self-esteem, interpersonal relationships, and occupational productivity. […] Disease severity should be measured using the HDSS. Treatment success is defined as a decrease in the HDSS score. Most treatment recommendations are based on expert consensus, because the evidence is poor (e.g., few study participants, nonrandomized trials, often not based on prospective trials). […] First-line treatment of all primary focal hyperhidrosis, regardless of severity, is topical 20% aluminum chloride (Drysol). This solution is applied nightly to the affected areas for six to eight hours until the HDSS score decreases, at which time the application interval can be lengthened to maintain sweat control. […] Botulinum toxin injection is the most studied hyperhidrosis treatment and demonstrates consistent improvement in HDSS scores and in sweat production as measured in the axillae and palms. It may be considered first- or second-line therapy for hyperhidrosis affecting the axillae, palms, soles, or face. […] Canadian guidelines recommend oral anticholinergics for treating primary hyperhidrosis with an HDSS score of 3 or 4 that does not resolve with topical aluminum chloride, onabotulinumtoxinA, or iontophoresis.
- #34 Hyperhidrosis – an unknown widespread „silent” disorderhttps://www.jneurology.com/articles/hyperhidrosis–an-unknown-widespread-silent-disorder.html
A major American study shows that 2.8 % of the population suffers from hyperhidrosis. […] The prognosis of hyperhidrosis is not known. For some, the problems pass but for many they remain for life. […] In most cases, it is easy to exclude or diagnose secondary hyperhidrosis without taking samples and performing examinations. […] Hyperhidrosis has an extremely negative impact on quality of life. […] The Dermatology Life Quality Index (DLQI) can be used to objectivise this, to assess treatment results and compare results with other skin diseases which are surveyed using the same questionnaire. […] Secondary hyperhidrosis may involve several specialties. […] A small amount of anamnestic data is usually enough to differentiate between primary and secondary hyperhidrosis, but sometimes anamnesis and status in diagnostics are insufficient and that is when it becomes relevant to take samples and do further examinations.
- #35 Diagnosis and qualitative identification of hyperhidrosis – Nawrocki – Shanghai Chesthttps://shc.amegroups.org/article/view/5191/html
HH is commonly determined in qualitative terms. […] The scoring systems used in questionnaires are subjective, reflecting a bias in data collection. […] Impact on QoL has evolved to be the most valuable and essential evaluation modality for PFHH. […] The Hyperhidrosis Disease Severity Scale (HDSS) is disease-specific, simple, and the most commonly used method for measuring QoL in HH patients. […] Although the diagnosis of HH is commonly based on subjective testimonies from HH patients, various quantitative and qualitative measurement tools are available to identify the disease, grade its severity, and provide appropriate and prompt treatment.
- #36 Hyperhidrosis – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/hyperhidrosis/diagnosis-treatment/drc-20367173
Diagnosing hyperhidrosis may start with your health care provider asking about your medical history and symptoms. You may also need a physical exam or tests to further evaluate the cause of your symptoms. […] Your health care provider may recommend blood, urine or other lab tests to see if your sweating is caused by another medical condition, such as an overactive thyroid (hyperthyroidism) or low blood sugar (hypoglycemia). […] Or you may need a test that pinpoints the areas of sweating and evaluates how severe your condition is. Two such tests are an iodine-starch test and a sweat test. […] Your health care provider is likely to ask you several questions, such as: When did the heavy sweating begin? Where on your body does it occur? Have your symptoms been continuous or occasional? What, if anything, seems to improve your symptoms? What, if anything, appears to worsen your symptoms?
- #37 Hyperhidrosis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK459227/
Diagnostic criteria for primary hyperhidrosis: Excessive sweating for 6 or more months, Sweating involves the axilla, palms, soles, and/or face, Sweating is bilateral and symmetric, Decreased or no sweating at night, Sweating episodes last at least 7 days, The individual is 25 years of age or younger, There is a family history, Sweating impairs daily living activities. […] If a secondary cause is suspected, providers should consider ordering a complete blood count, basic metabolic panel, thyroid-stimulating hormone, sedimentation rate, antinuclear antibody, hemoglobin A1C, and chest x-ray. These tests assist in ruling out infection, kidney dysfunction, malignancy, diabetes mellitus, thyroid disease, an inflammatory disorder, or connective tissue disease, which can all be associated with hyperhidrosis.
- #38 Hyperhidrosis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK459227/
Diagnostic criteria for primary hyperhidrosis: Excessive sweating for 6 or more months, Sweating involves the axilla, palms, soles, and/or face, Sweating is bilateral and symmetric, Decreased or no sweating at night, Sweating episodes last at least 7 days, The individual is 25 years of age or younger, There is a family history, Sweating impairs daily living activities. […] If a secondary cause is suspected, providers should consider ordering a complete blood count, basic metabolic panel, thyroid-stimulating hormone, sedimentation rate, antinuclear antibody, hemoglobin A1C, and chest x-ray. These tests assist in ruling out infection, kidney dysfunction, malignancy, diabetes mellitus, thyroid disease, an inflammatory disorder, or connective tissue disease, which can all be associated with hyperhidrosis.
- #39 Hyperhidrosis (Excessive Sweating) | Doctorhttps://patient.info/doctor/hyperhidrosis
Diagnosing hyperhidrosis (investigations) If the presentation is characteristic of primary focal hyperhidrosis and there is no evidence of an underlying cause, no laboratory tests are required. Any initial investigations will often depend on individual context of patient and the history and examination but often include: FBC; blood film for malarial parasites may be indicated. ESR and/or CRP. Renal function tests and electrolytes. LFTs. Fasting blood glucose. TFTs. HIV testing. Tuberculosis testing 24 hour urinary collection for catecholamines, metanephrines (to exclude phaeochromocytoma), 5-hydroxyindoleacetic acid (to exclude carcinoid tumours). CXR. […] Diagnose primary focal hyperhidrosis when focal, visible, excessive sweating: Occurs in at least one of the following sites: axillae, palms, soles, or craniofacial region; and Has lasted at least six months; and Has no apparent cause; and Has at least two of the following characteristics: Bilateral and relatively symmetrical. Impairs daily activities. Frequency of at least one episode per week. Onset before 25 years of age. Positive family history. Cessation of local sweating during sleep. […] If symptoms have lasted less than six months or onset is at 25 years of age or older, primary focal hyperhidrosis remains a likely diagnosis if other criteria are met, but extra care should be taken to exclude an underlying cause.
- #40 Hyperhidrosis (Excessive Sweating) | Doctorhttps://patient.info/doctor/hyperhidrosis
Diagnosing hyperhidrosis (investigations) If the presentation is characteristic of primary focal hyperhidrosis and there is no evidence of an underlying cause, no laboratory tests are required. Any initial investigations will often depend on individual context of patient and the history and examination but often include: FBC; blood film for malarial parasites may be indicated. ESR and/or CRP. Renal function tests and electrolytes. LFTs. Fasting blood glucose. TFTs. HIV testing. Tuberculosis testing 24 hour urinary collection for catecholamines, metanephrines (to exclude phaeochromocytoma), 5-hydroxyindoleacetic acid (to exclude carcinoid tumours). CXR. […] Diagnose primary focal hyperhidrosis when focal, visible, excessive sweating: Occurs in at least one of the following sites: axillae, palms, soles, or craniofacial region; and Has lasted at least six months; and Has no apparent cause; and Has at least two of the following characteristics: Bilateral and relatively symmetrical. Impairs daily activities. Frequency of at least one episode per week. Onset before 25 years of age. Positive family history. Cessation of local sweating during sleep. […] If symptoms have lasted less than six months or onset is at 25 years of age or older, primary focal hyperhidrosis remains a likely diagnosis if other criteria are met, but extra care should be taken to exclude an underlying cause.
- #41 Hyperhidrosis – Symptoms, diagnosis and treatment | BMJ Best Practicehttps://bestpractice.bmj.com/topics/en-gb/856
Hyperhidrosis is an excess sweating condition beyond physiological need. […] Classified as primary and of unknown cause (idiopathic), or secondary due to an underlying condition (usually an infectious, endocrine, or neurological disorder). […] Primary hyperhidrosis may also be described as palmar, plantar, axillary, and craniofacial, each of which has its own clinical characteristics. […] Treatment options for primary hyperhidrosis include medical and surgical treatments. […] Key diagnostic factors include presence of risk factors, excessive palmar sweating, excessive plantar sweating, onset in early childhood or puberty, exacerbation of palmar sweating with use of hand lotion, severe facial sweating, severe axillary sweating, and generalised sweating. […] Investigations to consider include starch-iodine test, gravimetry, thyroid function test, metabolic panel, 24-hour urine collection for catecholamines, metanephrines, normetanephrines, serum free metanephrines, normetanephrines, urine 5-hydroxyindoleacetic acid, chest x-ray, and CT scans.
- #42 Hyperhidrosis: Symptoms, Causes, Treatmenthttps://www.health.com/condition/hyperhidrosis-overview
Imaging tests can be important for hyperhidrosis. A healthcare provider may use an imaging test if they believe a tumor may be causing you to sweat excessively. […] The paper test is a way to measure how much sweat occurs. Higher amounts of sweat absorbed by the special paper make the paper feel heavier. […] With a starch-iodine test, a provider applies an iodine solution to the affected areas, allows it to dry, and sprinkles starch on the area. A dark blue to black color indicates an area with a high amount of sweat.
- #43 Hyperhidrosis and bromhidrosis A guide to assessment and managementhttps://www.racgp.org.au/afp/2013/may/hyperhidrosis-and-bromhidrosis
A diagnosis of idiopathic focal hyperhidrosis can be made on history if the patient is noted to have excessive visible sweating for at least 6 months and two of the following: bilateral symmetrical sweating, impairment of daily activities, at least one episode per week, onset before 25 years of age, positive family history, focal sweating that ceases during sleep. […] If there is no obvious underlying cause on history and examination, and the presentation is characteristic for primary focal hyperhidrosis, then further investigations are not required.
- #44 Hyperhidrosis | Children’s Hospital of Philadelphiahttps://www.chop.edu/conditions-diseases/hyperhidrosis
After ruling out all potential causes of secondary hyperhidrosis, the diagnosis of primary focal hyperhidrosis is made by physical exam and a detailed evaluation of the patients signs and symptoms. No special diagnostic tests or imaging studies are required. The diagnosis is usually made by the patients pediatrician or dermatologist. […] Primary hyperhidrosis occurs because the nerves that innervate and activate the sweat glands of the hands are constantly working and sending signals so that glands will sweat, regardless of the social situation, regardless of the temperature. […] The operation is very safe and the incidence of surgical complications is extremely low, and the effectiveness of the surgery to cure the excessive sweating on the hands is just about 100 percent.
- #45 Hyperhidrosis | NHS informhttps://www.nhsinform.scot/illnesses-and-conditions/skin-hair-and-nails/hyperhidrosis/
The National Institute for Health and Care Excellence (NICE) recommends that ETS can be used to treat excessive sweating of the palms or underarms. […] Hyperhidrosis increases the risk of developing fungal infections, particularly on the feet most commonly fungal nail infections and athletes foot. […] The emotional impact of living with hyperhidrosis can be severe. Many people with the condition feel unhappy and, in some cases, depressed.
- #46 Hyperhidrosis: Management Options | AAFPhttps://www.aafp.org/pubs/afp/issues/2018/0601/p729.html
Hyperhidrosis negatively impacts daily life, especially emotional well-being, self-esteem, interpersonal relationships, and occupational productivity. […] Disease severity should be measured using the HDSS. Treatment success is defined as a decrease in the HDSS score. Most treatment recommendations are based on expert consensus, because the evidence is poor (e.g., few study participants, nonrandomized trials, often not based on prospective trials). […] First-line treatment of all primary focal hyperhidrosis, regardless of severity, is topical 20% aluminum chloride (Drysol). This solution is applied nightly to the affected areas for six to eight hours until the HDSS score decreases, at which time the application interval can be lengthened to maintain sweat control. […] Botulinum toxin injection is the most studied hyperhidrosis treatment and demonstrates consistent improvement in HDSS scores and in sweat production as measured in the axillae and palms. It may be considered first- or second-line therapy for hyperhidrosis affecting the axillae, palms, soles, or face. […] Canadian guidelines recommend oral anticholinergics for treating primary hyperhidrosis with an HDSS score of 3 or 4 that does not resolve with topical aluminum chloride, onabotulinumtoxinA, or iontophoresis.
- #47 Diagnosis Guidelines – International Hyperhidrosis Society | Official Sitehttps://www.sweathelp.org/about-hyperhidrosis/diagnosis-guidelines.html
The approach to diagnosis of primary hyperhidrosis (Hh) starts with using one or more methods of assessment of severity of sweating. Practical, qualitative, and quantitative methods are available to aid the clinician in confirming the diagnosis. A logical approach to making a clinical diagnosis is presented, along with a diagnostic algorithm outlining this approach. […] During the evaluation of a patient with primary hyperhidrosis, it is sometimes necessary to assess the rate of sweat production, the specific areas involved, and the effect of the condition on the patients quality of life, psycho-social wellness, and daily activities. […] Primary hyperhidrosis has specific and characteristic findings such that Adar and colleagues feel the diagnosis can be made on the basis of history and physical alone.
- #48 Diagnosing Hyperhidrosis – International Hyperhidrosis Society | Official Sitehttps://www.sweathelp.org/home/diagnosing-hyperhidrosis.html
If you suffer from excessive sweating, chances are, you suffer every day. […] To help your clinician, your health insurance plan, even your friends and loved ones understand how much hyperhidrosis negatively affects you, its useful to think about and keep track of its daily effects. […] While it’s important to document how excessive sweating impacts the quality of your life, it’s also key to understand that there are two main types of hyperhidrosis–primary focal and secondary generalized–and your next step is to learn the difference so you can move forward in finding relief. […] How will your clinician diagnose hyperhidrosis? Ideally, the following ABCs will be factored in: […] For a primary Hh diagnosis, excessive sweating symptoms or episodes that have been going on for 6+ months with 2+ episodes per week are considered.
- #49 Diagnosis Guidelines – International Hyperhidrosis Society | Official Sitehttps://www.sweathelp.org/about-hyperhidrosis/diagnosis-guidelines.html
In summary, although the Hh diagnosis can usually be made on the basis of history and observed excessive sweating, gravimetric measurement may also provide a quantitative assessment. […] Given the potential for overlap in sweating rates between patients with hyperhidrosis and healthy controls, it is important to gauge the severity of social embarrassment and the effects on quality of life and impairment of daily activities in order to plan treatment, especially if more than one area is involved. […] The first step in the evaluation of a patient’s excessive sweating is to distinguish between primary and secondary hyperhidrosis. […] After this has been done, a diagnosis of primary (or idiopathic) Hh can be solidified using the ABCs, below. […] For a primary Hh diagnosis, look for excessive sweating symptoms or episodes (2 or more per week) that started 6+ months ago and appear to be chronic. […] Primary Hh does not cause excessive sweating during sleep.
- #50 Diagnosis and qualitative identification of hyperhidrosis – Nawrocki – Shanghai Chesthttps://shc.amegroups.org/article/view/5191/html
Hyperhidrosis is a dermatologic disease defined as excessive sweating that exceeds thermoregulatory needs, and is estimated to affect at least 4.8% of the population. […] The diagnosis is partially determined and supported by objective quantitative tools, but is mainly identified by subjective accounts of patients regarding the extent of impact the excessive sweating has on their daily and general quality of life. […] Early diagnosis and proper treatment of PFHH are essential for minimizing its emotional, psychosocial, and physical effects. […] PFHH has distinguishable characteristics, allowing its diagnosis to be made solely on the medical history and physical examination. […] After establishing a diagnosis of PFHH, severity is determined. […] Various quantitative and qualitative methods are available to establish a diagnosis of HH, its severity, and the effect the condition has on a patients QoL.
- #51 Diagnosis Guidelines – International Hyperhidrosis Society | Official Sitehttps://www.sweathelp.org/about-hyperhidrosis/diagnosis-guidelines.html
In summary, although the Hh diagnosis can usually be made on the basis of history and observed excessive sweating, gravimetric measurement may also provide a quantitative assessment. […] Given the potential for overlap in sweating rates between patients with hyperhidrosis and healthy controls, it is important to gauge the severity of social embarrassment and the effects on quality of life and impairment of daily activities in order to plan treatment, especially if more than one area is involved. […] The first step in the evaluation of a patient’s excessive sweating is to distinguish between primary and secondary hyperhidrosis. […] After this has been done, a diagnosis of primary (or idiopathic) Hh can be solidified using the ABCs, below. […] For a primary Hh diagnosis, look for excessive sweating symptoms or episodes (2 or more per week) that started 6+ months ago and appear to be chronic. […] Primary Hh does not cause excessive sweating during sleep.
- #52 How Hyperhidrosis Is Diagnosedhttps://www.verywellhealth.com/hyperhidrosis-diagnosis-4778629
These criteria clearly differentiate the difference between primary focal hyperhidrosis and secondary hyperhidrosis and are intended to help the physician provide the optimal treatment. […] The process of differentiating between two (or more) medical conditions that have the same or similar symptoms is called a differential diagnosis. […] There are several conditions that have the same signs and symptoms of hyperhidrosis. […] Each of the above conditions causes secondary, generalized, diffuse sweating, except spinal cord injury and reflex sympathetic dystrophy, which involve sweating in focal areas.
- #53 Evaluation of the patient with night sweats or generalized hyperhidrosis – UpToDatehttps://www.uptodate.com/contents/evaluation-of-the-patient-with-night-sweats-or-generalized-hyperhidrosis
Evaluation of the patient with night sweats or generalized hyperhidrosis […] The evaluation of the patient with night sweats or generalized hyperhidrosis is discussed here. […] Excessive sweating, or generalized hyperhidrosis, is the secretion of sweat in excess of that needed to control body temperature. It may be primary (idiopathic) or secondary (due to an underlying cause). […] Night sweats (sleep hyperhidrosis) are episodes of generalized hyperhidrosis that occur during sleep and may range in severity from moderate diffuse sweating to drenching sweats that require changing bedclothes and even bed sheets.
- #54 Hyperhidrosis (Excessive Sweating) | Doctorhttps://patient.info/doctor/hyperhidrosis
Diagnosing hyperhidrosis (investigations) If the presentation is characteristic of primary focal hyperhidrosis and there is no evidence of an underlying cause, no laboratory tests are required. Any initial investigations will often depend on individual context of patient and the history and examination but often include: FBC; blood film for malarial parasites may be indicated. ESR and/or CRP. Renal function tests and electrolytes. LFTs. Fasting blood glucose. TFTs. HIV testing. Tuberculosis testing 24 hour urinary collection for catecholamines, metanephrines (to exclude phaeochromocytoma), 5-hydroxyindoleacetic acid (to exclude carcinoid tumours). CXR. […] Diagnose primary focal hyperhidrosis when focal, visible, excessive sweating: Occurs in at least one of the following sites: axillae, palms, soles, or craniofacial region; and Has lasted at least six months; and Has no apparent cause; and Has at least two of the following characteristics: Bilateral and relatively symmetrical. Impairs daily activities. Frequency of at least one episode per week. Onset before 25 years of age. Positive family history. Cessation of local sweating during sleep. […] If symptoms have lasted less than six months or onset is at 25 years of age or older, primary focal hyperhidrosis remains a likely diagnosis if other criteria are met, but extra care should be taken to exclude an underlying cause.
- #55 Hyperhidrosis – Dermatologic Disorders – Merck Manual Professional Editionhttps://www.merckmanuals.com/professional/dermatologic-disorders/sweating-disorders/hyperhidrosis
Hyperhidrosis can be focal or generalized. […] Diagnosis is obvious, but tests for underlying causes may be indicated. […] Hyperhidrosis can be primary or secondary to an underlying medical condition. It is diagnosed by history and examination but can be confirmed with the iodine and starch test. […] Laboratory tests to identify a cause of hyperhidrosis are guided by the patient’s other symptoms and might include, for example, complete blood count to detect leukemia, serum glucose to detect diabetes, and thyroid-stimulating hormone to screen for thyroid dysfunction. […] Asymmetry in the pattern of sweating suggests a neurologic cause. […] Treat using aluminum chloride solutions, tap-water iontophoresis, oral or topical anticholinergic medications, oral clonidine, botulinum toxin, or a microwaved-based or laser device. […] Consider surgical options in patients who do not respond to medications or device therapy; surgical options include excision of axillary sweat glands and endoscopic transthoracic sympathectomy for palmar sweating, which carries risk of significant adverse effects.
- #56 Hyperhidrosis – Wikipediahttps://en.wikipedia.org/wiki/Hyperhidrosis
Hyperhidrosis can lead to difficulties in professional fields, with more than 80% of patients experiencing moderate to severe emotional effects from the disease. […] To diagnose this condition, a dermatologist gives the person a physical exam. This includes looking closely at the areas of the body that sweat excessively. A dermatologist also asks very specific questions. This helps the physician understand why the person has excessive sweating. Sometimes medical testing is necessary. Some patients require a test called the sweat test. This involves coating some of their skin with a powder that turns purple when the skin gets wet. […] Excessive sweating affecting only one side of the body is more suggestive of secondary hyperhidrosis and further investigation for a neurologic cause is recommended.
- #57 Hyperhidrosis: Diagnosis and treatmenthttps://www.aad.org/public/diseases/a-z/hyperhidrosis-treatment
If youre living with excessive sweating, treatment can improve your quality of life. Effective treatment begins with an accurate diagnosis, which tells you the type of hyperhidrosis you have. […] To find out if you have hyperhidrosis, your dermatologist will ask you questions. […] To give you an accurate diagnosis, you may need a physical exam, medical testing, or both. These can find some possible causes of your excessive sweating. […] Once your dermatologist has all the necessary information, they will talk with you about your condition. […] Patients diagnosed with primary hyperhidrosis (not due to a medication or medical condition) require treatment to control excessive sweating. […] To treat hyperhidrosis, your dermatologist will create an individualized treatment plan based on: The type of hyperhidrosis you have, Your symptoms, Where on your body you sweat heavily, Your preferences for treatment.
- #58 What Doctor Should You See For Hyperhidrosis? – Thompson Teehttps://thompsontee.com/blog/should-you-see-a-hyperhidrosis-doctor/?srsltid=AfmBOooQQX0JCmngOM3L2qZG9THxIIqm8EV-SIaqO95mcBRZsjbpryp_
Consider seeing a doctor for hyperhidrosis, so you can navigate your sweaty predicament and live more comfortably. […] Here are some indicators you may need to talk to your doctor about hyperhidrosis: You sweat through clothing often and change throughout the day. […] Excessive sweating may also be a sign of something more serious. Seek medical attention if: You experience lightheadedness, chest pain, heart palpitations, shortness of breath or nausea in addition to heavy sweating. […] Even if you only sweat more in high-stress situations, it can be helpful to talk to a doctor who understands hyperhidrosis, so they can help you try more effective treatment options. […] Many doctors can treat hyperhidrosis. […] Professional hyperhidrosis treatment usually starts with your primary care physician.
- #59 Excessive Sweating (Hyperhidrosis): Signs, Treatment & Causeshttps://www.medicinenet.com/hyperhidrosis/article.htm
How do healthcare professionals diagnose hyperhidrosis? The diagnosis is made clinically based on a patient’s history and physical examination. If the sweating is excessive and constant, then the diagnosis is obvious. It is not unusual that one must rely on the patient’s history to determine the diagnosis. Research centers measure sweat production by comparing the weight of filter paper left on the skin for a specified interval before and after sweating. […] Dermatologists are physicians specialized in diagnosing and treating skin conditions. Dermatologists diagnose and treat this condition.
- #60 What Doctor Should You See For Hyperhidrosis? – Thompson Teehttps://thompsontee.com/blog/should-you-see-a-hyperhidrosis-doctor/?srsltid=AfmBOooQQX0JCmngOM3L2qZG9THxIIqm8EV-SIaqO95mcBRZsjbpryp_
If over-the-counter antiperspirants and prescription options dont work, your doctor may refer you to a dermatologist. […] Some clinics in the U.S. are devoted to the treatment and management of hyperhidrosis. […] If you have severe hyperhidrosis, your dermatologist may refer you to a neurologist. […] Surgery for hyperhidrosis should be a last resort. […] The International Hyperhidrosis Society is an independent, non-profit advocacy group supporting meaningful improvements in hyperhidrosis diagnosis, care and understanding. […] To find the right treatment, your doctor will ask for details about your sweating. […] Depending on the severity of your sweating, your doctor may also order tests. […] Your doctor may order blood tests to check for secondary hyperhidrosis, excessive sweating caused by another medical condition.
- #61 Hyperhidrosis: Diagnosis and treatmenthttps://www.aad.org/public/diseases/a-z/hyperhidrosis-treatment
If youre living with excessive sweating, treatment can improve your quality of life. Effective treatment begins with an accurate diagnosis, which tells you the type of hyperhidrosis you have. […] To find out if you have hyperhidrosis, your dermatologist will ask you questions. […] To give you an accurate diagnosis, you may need a physical exam, medical testing, or both. These can find some possible causes of your excessive sweating. […] Once your dermatologist has all the necessary information, they will talk with you about your condition. […] Patients diagnosed with primary hyperhidrosis (not due to a medication or medical condition) require treatment to control excessive sweating. […] To treat hyperhidrosis, your dermatologist will create an individualized treatment plan based on: The type of hyperhidrosis you have, Your symptoms, Where on your body you sweat heavily, Your preferences for treatment.
- #62 Hyperhidrosis – an unknown widespread „silent” disorderhttps://www.jneurology.com/articles/hyperhidrosis–an-unknown-widespread-silent-disorder.html
A major American study shows that 2.8 % of the population suffers from hyperhidrosis. […] The prognosis of hyperhidrosis is not known. For some, the problems pass but for many they remain for life. […] In most cases, it is easy to exclude or diagnose secondary hyperhidrosis without taking samples and performing examinations. […] Hyperhidrosis has an extremely negative impact on quality of life. […] The Dermatology Life Quality Index (DLQI) can be used to objectivise this, to assess treatment results and compare results with other skin diseases which are surveyed using the same questionnaire. […] Secondary hyperhidrosis may involve several specialties. […] A small amount of anamnestic data is usually enough to differentiate between primary and secondary hyperhidrosis, but sometimes anamnesis and status in diagnostics are insufficient and that is when it becomes relevant to take samples and do further examinations.
- #63 Diagnosis Guidelines for Hyperhidrosis – Focus on Hyperhidrosishttps://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/diagnosis-guidelines-hyperhidrosis/2073
The approach to diagnosis of primary hyperhidrosis (Hh) starts with using one or more methods of assessment of severity of sweating. Practical, qualitative, and quantitative methods are available to aid the physician in confirming the diagnosis. A logical approach to making a clinical diagnosis is presented, along with a diagnostic algorithm outlining this approach. […] During the evaluation of a patient with primary hyperhidrosis, it is sometimes necessary to assess the rate of sweat production, the specific areas involved, and the effect of the condition on the patientâs quality of life, psycho-social wellness, and daily activities. […] The first step in the evaluation of a patient’s excessive sweating is to distinguish between primary and secondary hyperhidrosis. Therapy for secondary Hh should be directed toward the underlying causative agent or illness. A history focusing on location of excessive sweating, the duration of the problem, family history, specific triggers, a review of systems, and a review of any medications being taken by the patient should allow the physician to distinguish whether the patient has 1) generalized sweating due to an underlying systemic illness or as a side effect of a medication or 2) focal sweating due to a neurologic disorder or primary hyperhidrosis. Primary hyperhidrosis has specific and characteristic findings such that Adar and colleagues feel the diagnosis can be made on the basis of history and physical alone. These findings include its occurrence in generally young, healthy patients with a family history and onset during childhood or adolescence. Primary Hh patients typically will have bilateral, symmetric involvement of palms, soles, and/or axillae (or other specific body areas or body area combinations).
- #64 Diagnosis Guidelines for Hyperhidrosis – Focus on Hyperhidrosishttps://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/diagnosis-guidelines-hyperhidrosis/2073
In summary, although the Hh diagnosis can usually be made on the basis of history and observed excessive sweating, gravimetric measurement may also provide a quantitative assessment. Given the potential for overlap in sweating rates between patients with hyperhidrosis and healthy controls, it is important to gauge the severity of social embarrassment and the effects on quality of life and impairment of daily activities in order to plan treatment, especially if more than one area is involved.
- #65 Diagnosis and qualitative identification of hyperhidrosis – Nawrocki – Shanghai Chesthttps://shc.amegroups.org/article/view/5191/html
Hyperhidrosis is a dermatologic disease defined as excessive sweating that exceeds thermoregulatory needs, and is estimated to affect at least 4.8% of the population. […] The diagnosis is partially determined and supported by objective quantitative tools, but is mainly identified by subjective accounts of patients regarding the extent of impact the excessive sweating has on their daily and general quality of life. […] Early diagnosis and proper treatment of PFHH are essential for minimizing its emotional, psychosocial, and physical effects. […] PFHH has distinguishable characteristics, allowing its diagnosis to be made solely on the medical history and physical examination. […] After establishing a diagnosis of PFHH, severity is determined. […] Various quantitative and qualitative methods are available to establish a diagnosis of HH, its severity, and the effect the condition has on a patients QoL.
- #66 Hyperhidrosis – 10 common questions about excessive sweatinghttps://www.hidroxa.com/en/hyperhidrosis
Hyperhidrosis – excessive sweating is a condition characterized by an abnormal sweating level that isnât caused necessarily by heat or exercise. […] The first step that dermatologists, clinicians, and doctors have to do when they are diagnosing excessive sweating is to differentiate if the condition is primary or secondary. […] Primary hyperhidrosis is of unknown cause, and secondary is a part of other conditions. […] Other medical conditions can also cause excessive sweating. If youâre experiencing severe sweat problems, you should contact a doctor to examine your case and exclude other diseases. […] The primary type is not visible on blood tests, even though the symptoms are severe. To make sure youâre getting the right diagnosis, we suggest that you seek out a proper sweat clinic.
- #67 Hyperhidrosis: Diagnosis and treatmenthttps://www.aad.org/public/diseases/a-z/hyperhidrosis-treatment
If youre living with excessive sweating, treatment can improve your quality of life. Effective treatment begins with an accurate diagnosis, which tells you the type of hyperhidrosis you have. […] To find out if you have hyperhidrosis, your dermatologist will ask you questions. […] To give you an accurate diagnosis, you may need a physical exam, medical testing, or both. These can find some possible causes of your excessive sweating. […] Once your dermatologist has all the necessary information, they will talk with you about your condition. […] Patients diagnosed with primary hyperhidrosis (not due to a medication or medical condition) require treatment to control excessive sweating. […] To treat hyperhidrosis, your dermatologist will create an individualized treatment plan based on: The type of hyperhidrosis you have, Your symptoms, Where on your body you sweat heavily, Your preferences for treatment.
- #68 Hyperhidrosis: Diagnosis and treatmenthttps://www.aad.org/public/diseases/a-z/hyperhidrosis-treatment
If other treatments fail to bring relief, surgery may be considered. Surgery can permanently stop excessive sweating in the treated area. When surgery is an option, your dermatologist will refer you to a surgeon. […] With a dermatologists help, you dont need to live with excessive sweating. Your dermatologist knows how to create a treatment plan that can reduce hyperhidrosis. Your plan may consist of one treatment or a combination of treatments.
- #69 Diagnosis and Management of Primary Hyperhidrosis: Practical Guidance and Current Therapy Update – JDDonline – Journal of Drugs in Dermatologyhttps://jddonline.com/articles/diagnosis-and-management-of-primary-hyperhidrosis-practical-guidance-and-current-therapy-update-S1545961620P0704X
Hyperhidrosis is a chronic medical condition characterized by excessive sweating beyond that which is necessary for thermoregulatory homeostasis. It is estimated to occur in 4.8% of the U.S. population (~15.3 million people) but is both underreported and underdiagnosed. […] Approximately half of those who self-identify as having excessive sweating do not discuss their symptoms with healthcare professionals despite the severe negative impact on their quality of life; reasons for this include the misconception that hyperhidrosis is not a medical condition and that no treatments exist. In one study, only half of patients who reported their symptoms to a healthcare professional were ultimately diagnosed with primary hyperhidrosis, which may reflect a reality of widespread underdiagnosis of the condition.
- #70 Hyperhidrosis – an unknown widespread „silent” disorderhttps://www.jneurology.com/articles/hyperhidrosis–an-unknown-widespread-silent-disorder.html
Owing to the frequency of severe and irreversible side effects, ETS is no longer performed in Sweden. […] Hyperhidrosis is a widespread disorder which is usually idiopathic but can be secondary to diseases involving several specialities. Examinations show that there is a strong negative impact on the quality of life of patients with hyperhidrosis.