Materiały źródłowe

• #1 Hyperhidrosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459227/

  Hyperhidrosis is classified as primary and secondary, and the management and treatment can significantly differ. […] Several treatment options for hyperhidrosis include topical aluminum chloride and oral anticholinergic medications, which are sufficient in patients with mild to moderate disease. […] First-line therapy for hyperhidrosis includes over-the-counter aluminum chloride hexahydrate 20% for 3 to 4 nights, then nightly as needed. […] Recently, topical glycopyrronium tosylate (premoistened cloth containing 2.4% glycopyrronium solution) was approved for treating sweating. […] If a patient does not respond to topical treatment or has more generalized symptoms, oral anticholinergic medications should be considered, including oxybutynin 5 mg to 10 mg daily or topical glycopyrrolate 0.5% to 2.0%.

• #2 Hyperhidrosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459227/

  Hyperhidrosis is classified as primary and secondary, and the management and treatment can significantly differ. […] Several treatment options for hyperhidrosis include topical aluminum chloride and oral anticholinergic medications, which are sufficient in patients with mild to moderate disease. […] First-line therapy for hyperhidrosis includes over-the-counter aluminum chloride hexahydrate 20% for 3 to 4 nights, then nightly as needed. […] Recently, topical glycopyrronium tosylate (premoistened cloth containing 2.4% glycopyrronium solution) was approved for treating sweating. […] If a patient does not respond to topical treatment or has more generalized symptoms, oral anticholinergic medications should be considered, including oxybutynin 5 mg to 10 mg daily or topical glycopyrrolate 0.5% to 2.0%.

• #3 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Hyperhidrosis is excessive sweating that affects patients’ quality of life, resulting in social and work impairment and emotional distress. Primary hyperhidrosis is bilaterally symmetric, focal, excessive sweating of the axillae, palms, soles, or craniofacial region not caused by other underlying conditions. Secondary hyperhidrosis may be focal or generalized, and is caused by an underlying medical condition or medication use. The Hyperhidrosis Disease Severity Scale is a validated survey used to grade the tolerability of sweating and its impact on quality of life. The score can be used to guide treatment. Topical aluminum chloride solution is the initial treatment in most cases of primary focal hyperhidrosis. Topical glycopyrrolate is first-line treatment for craniofacial sweating. Botulinum toxin injection (onabotulinumtoxinA) is considered first- or second-line treatment for axillary, palmar, plantar, or craniofacial hyperhidrosis. Iontophoresis should be considered for treating hyperhidrosis of the palms and soles. Oral anticholinergics are useful adjuncts in severe cases of hyperhidrosis when other treatments fail. Local microwave therapy is a newer treatment option for axillary hyperhidrosis. Local surgery and endoscopic thoracic sympathectomy should be considered in severe cases of hyperhidrosis that have not responded to topical or medical therapies.

• #4 Hyperhidrosis – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/hyperhidrosis/diagnosis-treatment/drc-20367173

  Diagnosing hyperhidrosis may start with your health care provider asking about your medical history and symptoms. […] Treating hyperhidrosis may start with treating the condition causing it. If a cause isn’t found, treatment focuses on controlling heavy sweating. If new self-care habits don’t improve your symptoms, your health care provider may suggest one or more of the following treatments. Even if your sweating improves after treatment, it may recur. […] Drugs used to treat hyperhidrosis include: […] Prescription antiperspirant. Your health care provider may prescribe an antiperspirant with aluminum chloride (Drysol, Xerac AC). Apply it to dry skin before going to bed. Then wash the product off when you get up, taking care to not get any in your eyes. Once you start seeing results from using it daily for a few days, you can scale back to once or twice a week to maintain the effect.

• #5 Hyperhidrosis – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/hyperhidrosis/diagnosis-treatment/drc-20367173

  Diagnosing hyperhidrosis may start with your health care provider asking about your medical history and symptoms. […] Treating hyperhidrosis may start with treating the condition causing it. If a cause isn’t found, treatment focuses on controlling heavy sweating. If new self-care habits don’t improve your symptoms, your health care provider may suggest one or more of the following treatments. Even if your sweating improves after treatment, it may recur. […] Drugs used to treat hyperhidrosis include: […] Prescription antiperspirant. Your health care provider may prescribe an antiperspirant with aluminum chloride (Drysol, Xerac AC). Apply it to dry skin before going to bed. Then wash the product off when you get up, taking care to not get any in your eyes. Once you start seeing results from using it daily for a few days, you can scale back to once or twice a week to maintain the effect.

• #6 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  First-line treatment of all primary focal hyperhidrosis, regardless of severity, is topical 20% aluminum chloride (Drysol). This solution is applied nightly to the affected areas for six to eight hours until the HDSS score decreases, at which time the application interval can be lengthened to maintain sweat control. The aluminum salts cause an obstruction of the eccrine sweat glands and destruction of the secretory cells. […] For craniofacial hyperhidrosis, topical 2% glycopyrrolate (compounded by a pharmacy) may be considered first-line treatment. It has shown a 96% success rate (as measured by gravimetric chemical analysis and non-HDSS quality-of-life surveys) with minimal adverse effects (mild skin irritation), and can be applied once every two to three days. […] Botulinum toxin injection is the most studied hyperhidrosis treatment and demonstrates consistent improvement in HDSS scores and in sweat production as measured in the axillae and palms. It may be considered first- or second-line therapy for hyperhidrosis affecting the axillae, palms, soles, or face.

• #7 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  First-line treatment of all primary focal hyperhidrosis, regardless of severity, is topical 20% aluminum chloride (Drysol). This solution is applied nightly to the affected areas for six to eight hours until the HDSS score decreases, at which time the application interval can be lengthened to maintain sweat control. The aluminum salts cause an obstruction of the eccrine sweat glands and destruction of the secretory cells. […] For craniofacial hyperhidrosis, topical 2% glycopyrrolate (compounded by a pharmacy) may be considered first-line treatment. It has shown a 96% success rate (as measured by gravimetric chemical analysis and non-HDSS quality-of-life surveys) with minimal adverse effects (mild skin irritation), and can be applied once every two to three days. […] Botulinum toxin injection is the most studied hyperhidrosis treatment and demonstrates consistent improvement in HDSS scores and in sweat production as measured in the axillae and palms. It may be considered first- or second-line therapy for hyperhidrosis affecting the axillae, palms, soles, or face.

• #8 Hyperhidrosis – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/hyperhidrosis/diagnosis-treatment/drc-20367173

  Prescription creams that contain glycopyrrolate may help hyperhidrosis that affects the face and head. Wipes soaked in glycopyrronium tosylate (Qbrexza) may ease symptoms of the hands, feet and underarms. […] Some pills (oral medications) block the nerves that trigger sweat glands. This can reduce sweating in some people. […] Some medications used for depression can also decrease sweating. They may also help decrease anxiety. […] Treatment with botulinum toxin (Botox) blocks the nerves that trigger the sweat glands. […] Your health care provider might suggest other treatments: […] With this home treatment, you soak your hands or feet in a pan of water while a device passes mild electric current through the water. The current blocks the nerves that trigger sweating. […] With this therapy, a handheld device (miraDry) delivers microwave energy to destroy sweat glands in the armpits.

• #9 Hyperhidrosis Treatment & Management: Medical Care, Surgical Care, Consultations

  https://emedicine.medscape.com/article/1073359-treatment

  Therapy for hyperhidrosis can be challenging for both the patient and the physician. Both topical and systemic medications have been used in the treatment of hyperhidrosis. Other treatment options for hyperhidrosis include iontophoresis and botulinum toxin injections. […] Topical agents for hyperhidrosis therapy include topical anticholinergics, boric acid, 2-5% tannic acid solutions, resorcinol, potassium permanganate, formaldehyde, glutaraldehyde, and methenamine. All of these agents are limited by staining, contact sensitization, irritancy, or limited effectiveness. These agents reduce perspiration by denaturing keratin and thereby occluding the pores of the sweat glands. They have a short-lasting effect. […] The two topical anticholinergic agents that are approved by the US Food and Drug Administration (FDA) for the treatment of primary axillary hyperhidrosis in adults and children aged 9 years or older are sofpironium topical gel (Sofdra) and glycopyrronium tosylate topical cloth (Oxvrexza).

• #10 Hyperhidrosis Treatment & Management: Medical Care, Surgical Care, Consultations

  https://emedicine.medscape.com/article/1073359-treatment

  Glycopyrronium tosylate topical cloth received FDA approval in June 2018 based on results from two phase 3 trials, ATMOS-1 and ATMOS-2. […] Sofpironium topical received FDA approval in June 2024 based on results from two phase 3 trials, CARDIGAN-1 and CARDIGAN-2. […] Because of the limitations of other agents, Drysol (20% aluminum chloride hexahydrate in absolute anhydrous ethyl alcohol) is more commonly used as the first-line topical agent. […] Axillary hyperhidrosis may be treated with aluminium chloride gel, although the gel may cause mild cutaneous irritation. […] Systemic agents used to treat hyperhidrosis include anticholinergic medications. Anticholinergics such as propantheline bromide, glycopyrrolate, oxybutynin, and benztropine are effective because the preglandular neurotransmitter for sweat secretion is acetylcholine.

• #11 Oral Medications – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/medications.html

  There are a number of oral (taken by mouth) prescription medications that may be used to help manage certain types of excessive sweating, either alone or (more often) in combination with other treatments like antiperspirants, injectables, miraDry, and/or iontophoresis. […] The most commonly used medications for managing excessive sweating are anticholinergics. […] Many hyperhidrosis patients experience success with anticholinergic therapy, especially when it’s used in combination with other sweat management techniques. […] Their use for hyperhidrosis is, thus, off-label. […] One IHhS Board member indicates that she prescribes oral medications (specifically glycopyrrolate and/or oxybutynin) for pediatric hyperhidrosis in children as young as 4 years and she reminds us that about 80% of all the medications used in children, for all sorts of conditions, are being used „off-label.”

• #12 Oral Medications – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/medications.html

  There are a number of oral (taken by mouth) prescription medications that may be used to help manage certain types of excessive sweating, either alone or (more often) in combination with other treatments like antiperspirants, injectables, miraDry, and/or iontophoresis. […] The most commonly used medications for managing excessive sweating are anticholinergics. […] Many hyperhidrosis patients experience success with anticholinergic therapy, especially when it’s used in combination with other sweat management techniques. […] Their use for hyperhidrosis is, thus, off-label. […] One IHhS Board member indicates that she prescribes oral medications (specifically glycopyrrolate and/or oxybutynin) for pediatric hyperhidrosis in children as young as 4 years and she reminds us that about 80% of all the medications used in children, for all sorts of conditions, are being used „off-label.”

• #13 Hyperhidrosis – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/hyperhidrosis/diagnosis-treatment/drc-20367173

  Prescription creams that contain glycopyrrolate may help hyperhidrosis that affects the face and head. Wipes soaked in glycopyrronium tosylate (Qbrexza) may ease symptoms of the hands, feet and underarms. […] Some pills (oral medications) block the nerves that trigger sweat glands. This can reduce sweating in some people. […] Some medications used for depression can also decrease sweating. They may also help decrease anxiety. […] Treatment with botulinum toxin (Botox) blocks the nerves that trigger the sweat glands. […] Your health care provider might suggest other treatments: […] With this home treatment, you soak your hands or feet in a pan of water while a device passes mild electric current through the water. The current blocks the nerves that trigger sweating. […] With this therapy, a handheld device (miraDry) delivers microwave energy to destroy sweat glands in the armpits.

• #14 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Canadian guidelines recommend oral anticholinergics for treating primary hyperhidrosis with an HDSS score of 3 or 4 that does not resolve with topical aluminum chloride, onabotulinumtoxinA, or iontophoresis. The most commonly used oral anticholinergic medications are oxybutynin and glycopyrrolate. […] A newer, noninvasive local treatment of axillary hyperhidrosis uses microwave technology. The application of microwave energy destroys eccrine sweat glands by creating local heat, resulting in cellular thermolysis. This outpatient procedure is applied with a handheld transducer after mapping the axillae using the Minor starch-iodine test. Local anesthesia is required. This treatment results in a decrease in the HDSS score of at least one point in 94% of patients and at least two points in 55% of patients.

• #15 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Canadian guidelines recommend oral anticholinergics for treating primary hyperhidrosis with an HDSS score of 3 or 4 that does not resolve with topical aluminum chloride, onabotulinumtoxinA, or iontophoresis. The most commonly used oral anticholinergic medications are oxybutynin and glycopyrrolate. […] A newer, noninvasive local treatment of axillary hyperhidrosis uses microwave technology. The application of microwave energy destroys eccrine sweat glands by creating local heat, resulting in cellular thermolysis. This outpatient procedure is applied with a handheld transducer after mapping the axillae using the Minor starch-iodine test. Local anesthesia is required. This treatment results in a decrease in the HDSS score of at least one point in 94% of patients and at least two points in 55% of patients.

• #16 Hyperhidrosis – Dermatologic Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/dermatologic-disorders/sweating-disorders/hyperhidrosis

  Glycopyrronium tosylate 2.4% cloth wipes are used to treat primary axillary hyperhidrosis in people 9 years of age and older. […] Glycopyrrolate or oxybutynin can be used to decrease sweating but can be limited by anticholinergic adverse effects, including dry mouth, dry skin, flushing, blurred vision, urinary retention, mydriasis, and cardiac arrhythmias. […] Oral clonidine is an alpha-2-adrenergic agonist that decreases sweating mediated by sympathetic nervous system activity. […] Botulinum toxin type A is a neurotoxin that decreases the release of acetylcholine from sympathetic nerves serving eccrine glands. […] Tap-water iontophoresis, in which salt ions are introduced into the skin using electric current, is an option for patients unresponsive to topical treatments; however, supporting data are limited.

• #17 Oral Medications – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/medications.html

  It should be noted that studies (in JAMA Neurology 2016 and JAMA Internal Medicine 2015) have reported a potential link between the development of dementia and/or brain atrophy and long-term, high-dose anticholinergic use by older people. […] Patients over (or near) the age of 65 may want to discuss these studies (JAMA Neurology 2016, JAMA Internal Medicine 2015) with their healthcare providers before embarking on or continuing anticholinergic therapy for excessive sweating. […] Besides possibly in the older age group (and more studies are needed on this), anticholinergics do not, in general, affect the central nervous system (the brain and spinal cord). […] These side effects can usually be managed by adjusting the individuals dose. […] There are non-pill formulations of anticholinergic medications for children and adults who are unable or unwilling to swallow the pills.

• #18 Oral Medications – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/medications.html

  It should be noted that studies (in JAMA Neurology 2016 and JAMA Internal Medicine 2015) have reported a potential link between the development of dementia and/or brain atrophy and long-term, high-dose anticholinergic use by older people. […] Patients over (or near) the age of 65 may want to discuss these studies (JAMA Neurology 2016, JAMA Internal Medicine 2015) with their healthcare providers before embarking on or continuing anticholinergic therapy for excessive sweating. […] Besides possibly in the older age group (and more studies are needed on this), anticholinergics do not, in general, affect the central nervous system (the brain and spinal cord). […] These side effects can usually be managed by adjusting the individuals dose. […] There are non-pill formulations of anticholinergic medications for children and adults who are unable or unwilling to swallow the pills.

• #19 Oral Medications – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/medications.html

  It should be noted that studies (in JAMA Neurology 2016 and JAMA Internal Medicine 2015) have reported a potential link between the development of dementia and/or brain atrophy and long-term, high-dose anticholinergic use by older people. […] Patients over (or near) the age of 65 may want to discuss these studies (JAMA Neurology 2016, JAMA Internal Medicine 2015) with their healthcare providers before embarking on or continuing anticholinergic therapy for excessive sweating. […] Besides possibly in the older age group (and more studies are needed on this), anticholinergics do not, in general, affect the central nervous system (the brain and spinal cord). […] These side effects can usually be managed by adjusting the individuals dose. […] There are non-pill formulations of anticholinergic medications for children and adults who are unable or unwilling to swallow the pills.

• #20 Oral Medications – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/medications.html

  It should be noted that studies (in JAMA Neurology 2016 and JAMA Internal Medicine 2015) have reported a potential link between the development of dementia and/or brain atrophy and long-term, high-dose anticholinergic use by older people. […] Patients over (or near) the age of 65 may want to discuss these studies (JAMA Neurology 2016, JAMA Internal Medicine 2015) with their healthcare providers before embarking on or continuing anticholinergic therapy for excessive sweating. […] Besides possibly in the older age group (and more studies are needed on this), anticholinergics do not, in general, affect the central nervous system (the brain and spinal cord). […] These side effects can usually be managed by adjusting the individuals dose. […] There are non-pill formulations of anticholinergic medications for children and adults who are unable or unwilling to swallow the pills.

• #21 Oral Medications – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/medications.html

  There are other oral medications besides anticholinergics that are successful in treating patients with specific types of hyperhidrosis, as well. […] Propranolol „calms down” the body, slows the heart rate and can help with sweating when you know you will be agitated or nervous. […] If you are interested in learning more about using oral medications to treat excessive sweating or as an adjunct/addition to other treatments, find a healthcare provider who is well-versed in hyperhidrosis care and oral medications in the IHhSs Clinician Finder database. […] If you’re considering an oral medication to treat excessive sweating, please know that experts in the field recommend that you try antiperspirants, Botox injections, or iontophoresis, too (or a combination of these).

• #22 Oral Medications – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/medications.html

  There are other oral medications besides anticholinergics that are successful in treating patients with specific types of hyperhidrosis, as well. […] Propranolol „calms down” the body, slows the heart rate and can help with sweating when you know you will be agitated or nervous. […] If you are interested in learning more about using oral medications to treat excessive sweating or as an adjunct/addition to other treatments, find a healthcare provider who is well-versed in hyperhidrosis care and oral medications in the IHhSs Clinician Finder database. […] If you’re considering an oral medication to treat excessive sweating, please know that experts in the field recommend that you try antiperspirants, Botox injections, or iontophoresis, too (or a combination of these).

• #23 Hyperhidrosis – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/hyperhidrosis/diagnosis-treatment/drc-20367173

  Prescription creams that contain glycopyrrolate may help hyperhidrosis that affects the face and head. Wipes soaked in glycopyrronium tosylate (Qbrexza) may ease symptoms of the hands, feet and underarms. […] Some pills (oral medications) block the nerves that trigger sweat glands. This can reduce sweating in some people. […] Some medications used for depression can also decrease sweating. They may also help decrease anxiety. […] Treatment with botulinum toxin (Botox) blocks the nerves that trigger the sweat glands. […] Your health care provider might suggest other treatments: […] With this home treatment, you soak your hands or feet in a pan of water while a device passes mild electric current through the water. The current blocks the nerves that trigger sweating. […] With this therapy, a handheld device (miraDry) delivers microwave energy to destroy sweat glands in the armpits.

• #24 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  First-line treatment of all primary focal hyperhidrosis, regardless of severity, is topical 20% aluminum chloride (Drysol). This solution is applied nightly to the affected areas for six to eight hours until the HDSS score decreases, at which time the application interval can be lengthened to maintain sweat control. The aluminum salts cause an obstruction of the eccrine sweat glands and destruction of the secretory cells. […] For craniofacial hyperhidrosis, topical 2% glycopyrrolate (compounded by a pharmacy) may be considered first-line treatment. It has shown a 96% success rate (as measured by gravimetric chemical analysis and non-HDSS quality-of-life surveys) with minimal adverse effects (mild skin irritation), and can be applied once every two to three days. […] Botulinum toxin injection is the most studied hyperhidrosis treatment and demonstrates consistent improvement in HDSS scores and in sweat production as measured in the axillae and palms. It may be considered first- or second-line therapy for hyperhidrosis affecting the axillae, palms, soles, or face.

• #25 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  First-line treatment of all primary focal hyperhidrosis, regardless of severity, is topical 20% aluminum chloride (Drysol). This solution is applied nightly to the affected areas for six to eight hours until the HDSS score decreases, at which time the application interval can be lengthened to maintain sweat control. The aluminum salts cause an obstruction of the eccrine sweat glands and destruction of the secretory cells. […] For craniofacial hyperhidrosis, topical 2% glycopyrrolate (compounded by a pharmacy) may be considered first-line treatment. It has shown a 96% success rate (as measured by gravimetric chemical analysis and non-HDSS quality-of-life surveys) with minimal adverse effects (mild skin irritation), and can be applied once every two to three days. […] Botulinum toxin injection is the most studied hyperhidrosis treatment and demonstrates consistent improvement in HDSS scores and in sweat production as measured in the axillae and palms. It may be considered first- or second-line therapy for hyperhidrosis affecting the axillae, palms, soles, or face.

• #26 Hyperhidrosis – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/hyperhidrosis/diagnosis-treatment/drc-20367173

  Prescription creams that contain glycopyrrolate may help hyperhidrosis that affects the face and head. Wipes soaked in glycopyrronium tosylate (Qbrexza) may ease symptoms of the hands, feet and underarms. […] Some pills (oral medications) block the nerves that trigger sweat glands. This can reduce sweating in some people. […] Some medications used for depression can also decrease sweating. They may also help decrease anxiety. […] Treatment with botulinum toxin (Botox) blocks the nerves that trigger the sweat glands. […] Your health care provider might suggest other treatments: […] With this home treatment, you soak your hands or feet in a pan of water while a device passes mild electric current through the water. The current blocks the nerves that trigger sweating. […] With this therapy, a handheld device (miraDry) delivers microwave energy to destroy sweat glands in the armpits.

• #27 Hyperhidrosis: Diagnosis and treatment

  https://www.aad.org/public/diseases/a-z/hyperhidrosis-treatment

  Studies show that botulinum toxin can be a safe and effective treatment for excessive sweating. […] Iontophoresis (eye-an-tuh-fuh-ree-sus) machine (hands and feet): This device is also called a portable anti-sweat machine. […] Microwave thermolysis (ther-moe-lie-sis) (underarms): This is a procedure that your dermatologist performs in the office, using a device that destroys sweat glands with heat. […] Sweat-control patch (underarms): The FDA cleared this patch to treat hyperhidrosis in the underarms of people 18 years of age and older. […] Several different oral (take by mouth) medications can be used. […] Propranolol (pro-PRAN-oh-lol) (excessive sweating due to anxiety or stress): Do you only sweat excessively when you become anxious or feel stressed? […] If other treatments fail to bring relief, surgery may be considered. Surgery can permanently stop excessive sweating in the treated area.

• #28 Treatment of Hyperhidrosis

  https://www.southcarolinablues.com/web/public/brands/medicalpolicyhb/external-policies/treatment-of-hyperhidrosis/

  The Hyperhidrosis Disease Severity Scale is used by patients to rate the severity of their symptoms on a scale of 1 to 4. […] Outcomes from different surgical and medical treatment modalities are best assessed using a combination of tools. Quantitative tools include gravimetry, evaporimetry, and the Minor starch-iodine test. Qualitative assessment tools include general health surveys and hyperhidrosis-specific surveys. Of these, the Hyperhidrosis Disease Severity Scale (Appendix Table 1) has had a good correlation to other assessment tools and is practical in the clinical setting. […] In 2004, botulinum toxin type A (Botox; Allergan Pharmaceuticals Ireland) was approved by the Food and Drug Administration (FDA) through the biologic license application process for use to treat primary axillary hyperhidrosis (severe underarm sweating) that cannot be managed by topical agents.

• #29 Hyperhidrosis Treatment & Management: Medical Care, Surgical Care, Consultations

  https://emedicine.medscape.com/article/1073359-treatment

  Iontophoresis was introduced in 1952 and consists of passing a direct current across the skin. […] Botulinum toxin injections are effective because of their anticholinergic effects at the neuromuscular junction and in the postganglionic sympathetic cholinergic nerves in the sweat glands. […] In palmar hyperhidrosis, 50 subepidermal injections of 2 mouse units per palm (total 100 mouse units per palm) results in anhydrosis lasting 4-12 months. […] Treatment of axillary hyperhidrosis with botulinum toxin type A reconstituted in lidocaine or in normal saline was described in a randomized, side-by-side, double-blind study. […] A 2008 study found botulinum toxin type A to be more effective than topical 20% aluminum chloride for the treatment of moderate-to-severe primary focal axillary hyperhidrosis.

• #30 Hyperhidrosis Treatment & Management: Medical Care, Surgical Care, Consultations

  https://emedicine.medscape.com/article/1073359-treatment

  Iontophoresis was introduced in 1952 and consists of passing a direct current across the skin. […] Botulinum toxin injections are effective because of their anticholinergic effects at the neuromuscular junction and in the postganglionic sympathetic cholinergic nerves in the sweat glands. […] In palmar hyperhidrosis, 50 subepidermal injections of 2 mouse units per palm (total 100 mouse units per palm) results in anhydrosis lasting 4-12 months. […] Treatment of axillary hyperhidrosis with botulinum toxin type A reconstituted in lidocaine or in normal saline was described in a randomized, side-by-side, double-blind study. […] A 2008 study found botulinum toxin type A to be more effective than topical 20% aluminum chloride for the treatment of moderate-to-severe primary focal axillary hyperhidrosis.

• #31 Botox injections one way to treat hyperhidrosis sweating | UCLA Health

  https://www.uclahealth.org/news/article/botox-injections-one-way-treat-hyperhidrosis-sweating

  Hyperhidrosis is a disorder in which the sweat glands become overactive. […] When it comes to managing the disorder, the antiperspirant your internist recommended is a common first-line approach. […] Nerve impulses associated with sweating can also be muted with the use of Botox. […] Botox injections have come to be widely used in managing primary hyperhidrosis when topical treatments have failed. […] The treatment works by blocking the nerve signals that instruct the sweat glands to become active. […] According to the International Hyperhidrosis Society, people who receive Botox injections have found excessive sweating decreases by more than 85%. […] Although Botox is widely used for many types of hyperhidrosis, at this time, it has been FDA approved only for excessive underarm sweating. […] With the failure of the antiperspirant to bring you relief, your internist can advise you on whether oral medications, Botox injections or surgery may be an appropriate next step.

• #32 Botox injections one way to treat hyperhidrosis sweating | UCLA Health

  https://www.uclahealth.org/news/article/botox-injections-one-way-treat-hyperhidrosis-sweating

  Hyperhidrosis is a disorder in which the sweat glands become overactive. […] When it comes to managing the disorder, the antiperspirant your internist recommended is a common first-line approach. […] Nerve impulses associated with sweating can also be muted with the use of Botox. […] Botox injections have come to be widely used in managing primary hyperhidrosis when topical treatments have failed. […] The treatment works by blocking the nerve signals that instruct the sweat glands to become active. […] According to the International Hyperhidrosis Society, people who receive Botox injections have found excessive sweating decreases by more than 85%. […] Although Botox is widely used for many types of hyperhidrosis, at this time, it has been FDA approved only for excessive underarm sweating. […] With the failure of the antiperspirant to bring you relief, your internist can advise you on whether oral medications, Botox injections or surgery may be an appropriate next step.

• #33 Hyperhidrosis | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/skin-hair-and-nails/hyperhidrosis/

  Hyperhidrosis can be challenging to treat and it may take a while to find a treatment right for you. […] Doctors usually recommend starting with the least invasive treatment first, such as powerful antiperspirants. […] If this doesn’t help, you may be advised to try treatments such as iontophoresis (the affected area is treated with a weak electric current passed through water or a wet pad), botulinum toxin injections, and even surgery in a few cases. […] Hyperhidrosis is usually a long-term condition, but some people experience an improvement with time and the treatments available can often keep the problem under control. […] If lifestyle changes and treatment don’t work, your GP may refer you to a dermatologist (a specialist in treating skin conditions) for further treatment, such as iontophoresis, botulinum toxin or surgery.

• #34 Hyperhidrosis Treatment San Diego | MedDerm

  https://medderm.net/hyperhidrosis-treatment/

  Hyperhidrosis is the condition characterized by abnormally increased perspiration, in excess of that required for regulation of body temperature. […] Hyperhidrosis can either be generalized or localized to specific parts of the body. Hands, feet, axillae, and the groin area are among the most active regions of perspiration due to the relatively high concentration of sweat glands. […] The most common treatment is aluminum chloride (hexahydrate) solution. The most common brands are Drysol, Maxim, Odaban, and Driclor. A 15% aluminum chloride solution or higher usually takes about a week of nightly use to stop the sweating, with one or two nightly applications per week to maintain the results. […] Iontophoresis is often effective in patients with hand or foot hyperhidrosis who do not respond to aluminum chloride.

• #35 Iontophoresis for Excessive Sweating | Baylor Medicine

  https://www.bcm.edu/healthcare/specialties/dermatology/excessive-sweating-options/iontophoresis-for-excessive-sweating

  Iontophoresis with water has been used since 1952 to treat excessive sweating of the hands and feet. The procedure uses a mild electrical current that is passed through tap water to temporarily shut off sweat glands. Tap water iontophoresis is generally effective within one month. In one study, 85 percent of patients with excessive perspiration of the palms had normalization of sweating. In another study, patients had an average of 81 percent improvement with treatment. Patients receive three treatments per week until the sweating is controlled (average of 10 treatments). Once sweating normalizes, patients may need as little as one treatment every 2-4 weeks for maintenance. […] Tap water iontophoresis is suitable for almost everybody with excessive sweating on the hands and feet.

• #36 Iontophoresis for Excessive Sweating | Baylor Medicine

  https://www.bcm.edu/healthcare/specialties/dermatology/excessive-sweating-options/iontophoresis-for-excessive-sweating

  Iontophoresis with water has been used since 1952 to treat excessive sweating of the hands and feet. The procedure uses a mild electrical current that is passed through tap water to temporarily shut off sweat glands. Tap water iontophoresis is generally effective within one month. In one study, 85 percent of patients with excessive perspiration of the palms had normalization of sweating. In another study, patients had an average of 81 percent improvement with treatment. Patients receive three treatments per week until the sweating is controlled (average of 10 treatments). Once sweating normalizes, patients may need as little as one treatment every 2-4 weeks for maintenance. […] Tap water iontophoresis is suitable for almost everybody with excessive sweating on the hands and feet.

• #37 Iontophoresis for Excessive Sweating | Baylor Medicine

  https://www.bcm.edu/healthcare/specialties/dermatology/excessive-sweating-options/iontophoresis-for-excessive-sweating

  Iontophoresis with water has been used since 1952 to treat excessive sweating of the hands and feet. The procedure uses a mild electrical current that is passed through tap water to temporarily shut off sweat glands. Tap water iontophoresis is generally effective within one month. In one study, 85 percent of patients with excessive perspiration of the palms had normalization of sweating. In another study, patients had an average of 81 percent improvement with treatment. Patients receive three treatments per week until the sweating is controlled (average of 10 treatments). Once sweating normalizes, patients may need as little as one treatment every 2-4 weeks for maintenance. […] Tap water iontophoresis is suitable for almost everybody with excessive sweating on the hands and feet.

• #38 Iontophoresis for Excessive Sweating | Baylor Medicine

  https://www.bcm.edu/healthcare/specialties/dermatology/excessive-sweating-options/iontophoresis-for-excessive-sweating

  Iontophoresis with water has been used since 1952 to treat excessive sweating of the hands and feet. The procedure uses a mild electrical current that is passed through tap water to temporarily shut off sweat glands. Tap water iontophoresis is generally effective within one month. In one study, 85 percent of patients with excessive perspiration of the palms had normalization of sweating. In another study, patients had an average of 81 percent improvement with treatment. Patients receive three treatments per week until the sweating is controlled (average of 10 treatments). Once sweating normalizes, patients may need as little as one treatment every 2-4 weeks for maintenance. […] Tap water iontophoresis is suitable for almost everybody with excessive sweating on the hands and feet.

• #39 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Canadian guidelines recommend oral anticholinergics for treating primary hyperhidrosis with an HDSS score of 3 or 4 that does not resolve with topical aluminum chloride, onabotulinumtoxinA, or iontophoresis. The most commonly used oral anticholinergic medications are oxybutynin and glycopyrrolate. […] A newer, noninvasive local treatment of axillary hyperhidrosis uses microwave technology. The application of microwave energy destroys eccrine sweat glands by creating local heat, resulting in cellular thermolysis. This outpatient procedure is applied with a handheld transducer after mapping the axillae using the Minor starch-iodine test. Local anesthesia is required. This treatment results in a decrease in the HDSS score of at least one point in 94% of patients and at least two points in 55% of patients.

• #40 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Canadian guidelines recommend oral anticholinergics for treating primary hyperhidrosis with an HDSS score of 3 or 4 that does not resolve with topical aluminum chloride, onabotulinumtoxinA, or iontophoresis. The most commonly used oral anticholinergic medications are oxybutynin and glycopyrrolate. […] A newer, noninvasive local treatment of axillary hyperhidrosis uses microwave technology. The application of microwave energy destroys eccrine sweat glands by creating local heat, resulting in cellular thermolysis. This outpatient procedure is applied with a handheld transducer after mapping the axillae using the Minor starch-iodine test. Local anesthesia is required. This treatment results in a decrease in the HDSS score of at least one point in 94% of patients and at least two points in 55% of patients.

• #41 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Canadian guidelines recommend oral anticholinergics for treating primary hyperhidrosis with an HDSS score of 3 or 4 that does not resolve with topical aluminum chloride, onabotulinumtoxinA, or iontophoresis. The most commonly used oral anticholinergic medications are oxybutynin and glycopyrrolate. […] A newer, noninvasive local treatment of axillary hyperhidrosis uses microwave technology. The application of microwave energy destroys eccrine sweat glands by creating local heat, resulting in cellular thermolysis. This outpatient procedure is applied with a handheld transducer after mapping the axillae using the Minor starch-iodine test. Local anesthesia is required. This treatment results in a decrease in the HDSS score of at least one point in 94% of patients and at least two points in 55% of patients.

• #42 Treatment of Hyperhidrosis

  https://www.southcarolinablues.com/web/public/brands/medicalpolicyhb/external-policies/treatment-of-hyperhidrosis/

  In 2011, the miraDry System (Miramar Labs) was cleared for marketing by FDA through the 510(k) process for treating primary axillary hyperhidrosis. This microwave device is designed to heat tissue at the dermal-hypodermal interface, the location of the sweat glands. […] The following information is to provide reference material. Inclusion does not imply endorsement or alignment with the evidence review conclusions. […] Guidelines or position statements will be considered for inclusion in Supplemental Information if they were issued by, or jointly by, a U.S. professional society, an international society with U.S. representation, or National Institute for Health and Care Excellence (NICE). […] In 2011, the Society of Thoracic Surgeons published an expert consensus statement on the surgical treatment of hyperhidrosis. The document stated that endoscopic thoracic sympathectomy is the treatment of choice for patients with primary hyperhidrosis.

• #43 Treatment of Hyperhidrosis

  https://www.southcarolinablues.com/web/public/brands/medicalpolicyhb/external-policies/treatment-of-hyperhidrosis/

  In 2011, the miraDry System (Miramar Labs) was cleared for marketing by FDA through the 510(k) process for treating primary axillary hyperhidrosis. This microwave device is designed to heat tissue at the dermal-hypodermal interface, the location of the sweat glands. […] The following information is to provide reference material. Inclusion does not imply endorsement or alignment with the evidence review conclusions. […] Guidelines or position statements will be considered for inclusion in Supplemental Information if they were issued by, or jointly by, a U.S. professional society, an international society with U.S. representation, or National Institute for Health and Care Excellence (NICE). […] In 2011, the Society of Thoracic Surgeons published an expert consensus statement on the surgical treatment of hyperhidrosis. The document stated that endoscopic thoracic sympathectomy is the treatment of choice for patients with primary hyperhidrosis.

• #44 Home – miraDry

  https://www.miradry.com/

  Invest in yourself with miraDry a treatment that saves you from the daily burden of underarm sweat and odor. […] The miraDry treatment is a procedure performed by a trained medical professional, in as little as one hour. […] The miraDry system uses thermal energy that targets and destroys the sweat glands, odor glands, and hair follicles in your underarm. Once those glands are eliminated, they do not grow back. […] The miraDry treatment is the only FDA-cleared treatment that can dramatically reduce underarm sweat and odor by addressing the root cause not the symptoms. […] miraDry is a treatment administered by a licensed healthcare practitioner that uses thermal energy to permanently eliminate sweat glands and significantly reduce sweat, odor and hair in as little as one treatment.

• #45 Home – miraDry

  https://www.miradry.com/

  Invest in yourself with miraDry a treatment that saves you from the daily burden of underarm sweat and odor. […] The miraDry treatment is a procedure performed by a trained medical professional, in as little as one hour. […] The miraDry system uses thermal energy that targets and destroys the sweat glands, odor glands, and hair follicles in your underarm. Once those glands are eliminated, they do not grow back. […] The miraDry treatment is the only FDA-cleared treatment that can dramatically reduce underarm sweat and odor by addressing the root cause not the symptoms. […] miraDry is a treatment administered by a licensed healthcare practitioner that uses thermal energy to permanently eliminate sweat glands and significantly reduce sweat, odor and hair in as little as one treatment.

• #46 Home – miraDry

  https://www.miradry.com/

  You can expect immediate and lasting results. Once the miraDry treatment eliminates the sweat and odor glands, they’re gone for good. The treatment is clinically proven to reduce sweat by 82% and 89% of patients were no longer bothered by odor. […] The miraDry system is FDA-cleared for the treatment of unwanted underarm sweat and odor, as well as the permanent removal of unwanted underarm hair. […] Outside the U.S., the miraDry system is intended for use by health care professionals for treatment of primary axillary hyperhidrosis (excessive sweating).

• #47 Treatment Overview – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/treatment-overview.html

  Additionally, healthcare providers and their patients are experimenting with combinations of treatments and getting good results. […] Underarm surgeries, such as liposuction, for excessive underarm sweating are being refined, but less invasive treatments should still be considered first. […] ETS surgery, although heavily advertised, is reserved for only certain severe cases of palmar hyperhidrosis (excessive sweating of the palms) that have not responded to any other treatment options or to combinations of treatments. […] Before considering ETS treatment, healthcare providers and their patients must fully consider and discuss the real risks of permanent damage and severe side effects including compensatory sweating. […] Everyones experience with this condition is different. […] So please be patient, explore all your options, explore combinations of options, adjust techniques, and work with your healthcare team to find the best treatments for your individual situation. […] Keep in mind, also, that research is still being conducted and new treatments, and new ways of using the current treatments, are being worked on.

• #48 Hyperhidrosis – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/hyperhidrosis/diagnosis-treatment/drc-20367173

  If you sweat heavily only in your armpits, your health care provider may suggest removing those sweat glands. […] During this procedure, the surgeon removes a small section of the spinal nerves that control sweating in your hands. […] Each of these procedures may be done with general anesthesia or with local anesthesia and sedation.

• #49 Hyperhidrosis Treatment & Management: Medical Care, Surgical Care, Consultations

  https://emedicine.medscape.com/article/1073359-treatment

  In addition to pharmacologic therapy, other treatments include surgical sympathectomy, radiofrequency ablation, surgical excision of the affected areas, and subcutaneous liposuction. […] Sympathectomy has been used as a permanent effective treatment since 1920. […] Two surgical approaches are available: an open approach and a newer endoscopic approach. […] Endoscopic thoracic sympathectomy is an effective treatment for hyperhidrosis; in one study, immediate positive results occurred in 832 (98%) of 850 patients. […] Surgical excision of the affected area (identified with iodine starch testing) removes the appropriate sweat glands, thereby eliminating sweating. This technique is particularly useful in axillary hyperhidrosis. […] The treatment of axillary hyperhidrosis using the 1064-nm Nd-YAG laser was found to be effective and safe in a pilot trial. […] Subcutaneous liposuction is another means of removing the eccrine sweat glands responsible for axillary hyperhidrosis.

• #50 Hyperhidrosis Treatment San Diego | MedDerm

  https://medderm.net/hyperhidrosis-treatment/

  Oral medication: There are several drugs available with varying degrees of success. A class of anticholinergic drugs are available that have shown to reduce hyperhidrosis. […] Surgery (Endoscopic Thoracic Sympathectomy or ETS): Select sympathetic nerves or nerve ganglia in the chest are either cut, burned or clamped to stop their transmission of impulses.

• #51 Hyperhidrosis Treatment & Management: Medical Care, Surgical Care, Consultations

  https://emedicine.medscape.com/article/1073359-treatment

  In addition to pharmacologic therapy, other treatments include surgical sympathectomy, radiofrequency ablation, surgical excision of the affected areas, and subcutaneous liposuction. […] Sympathectomy has been used as a permanent effective treatment since 1920. […] Two surgical approaches are available: an open approach and a newer endoscopic approach. […] Endoscopic thoracic sympathectomy is an effective treatment for hyperhidrosis; in one study, immediate positive results occurred in 832 (98%) of 850 patients. […] Surgical excision of the affected area (identified with iodine starch testing) removes the appropriate sweat glands, thereby eliminating sweating. This technique is particularly useful in axillary hyperhidrosis. […] The treatment of axillary hyperhidrosis using the 1064-nm Nd-YAG laser was found to be effective and safe in a pilot trial. […] Subcutaneous liposuction is another means of removing the eccrine sweat glands responsible for axillary hyperhidrosis.

• #52 Hyperhidrosis Treatment FAQs | Mount Sinai – New York

  https://www.mountsinai.org/care/thoracic-surgery/services/hyperhidrosis/treatment-faqs

  We can treat mild forms of hyperhidrosis without surgery. The most common approaches include use of astringents, talc or starch, sedatives, antihistamine medicines, or beta blockers. We can also try more aggressive therapy such as liposuction, botulinum toxin injections, or iontophoresis. If these do not work, we can offer surgical treatment. […] The most effective treatment for hyperhidrosis is endoscopic thoracic sympathectomy (ETS), a surgical procedure. We use special equipment to cut the sympathetic nerves at a precise location. The surgery takes about 40 minutes and requires two small (about 1.5 centimeters) incisions, one on each side of the chest. We use a camera so we can see the nerves. This procedure affects only the nerves to the armpits and hands. We do not use this procedure to treat the nerves to the face or feet.

• #53 Hyperhidrosis Treatment FAQs | Mount Sinai – New York

  https://www.mountsinai.org/care/thoracic-surgery/services/hyperhidrosis/treatment-faqs

  You should see a dramatic improvement practically from the moment you awaken from the anesthetic. These effects are permanent for almost everyone. […] Although ETS is a minimally invasive surgical procedure, you may feel some pain shortly after the surgery. Most people only feel pain by the incision sites and the nerves near the incisions. You may also feel some chest discomfort for the first one to three days after surgery. Most patients return to normal activity after about a week. Your body continues to heal after any surgical procedure for weeks or months. In some patients, the healing process will take a little longer. People with diabetes and people who smoke tend to take longer to heal. […] We use general anesthetic for this surgery. You should be able to leave on the same day of surgery.

• #54 Hyperhidrosis Treatment FAQs | Mount Sinai – New York

  https://www.mountsinai.org/care/thoracic-surgery/services/hyperhidrosis/treatment-faqs

  You should see a dramatic improvement practically from the moment you awaken from the anesthetic. These effects are permanent for almost everyone. […] Although ETS is a minimally invasive surgical procedure, you may feel some pain shortly after the surgery. Most people only feel pain by the incision sites and the nerves near the incisions. You may also feel some chest discomfort for the first one to three days after surgery. Most patients return to normal activity after about a week. Your body continues to heal after any surgical procedure for weeks or months. In some patients, the healing process will take a little longer. People with diabetes and people who smoke tend to take longer to heal. […] We use general anesthetic for this surgery. You should be able to leave on the same day of surgery.

• #55 Hyperhidrosis Treatment FAQs | Mount Sinai – New York

  https://www.mountsinai.org/care/thoracic-surgery/services/hyperhidrosis/treatment-faqs

  When an incision is made, there is a small risk of infection, bleeding, or healing issues at the surgical sites. We use general anesthesia, so there are the risks associated with that process. Some patients have bad reactions to medications used. Your surgeon will discuss the surgical risks with you in greater detail. […] The most bothersome side effect is excessive sweating on the back, abdomen, thighs, or lower legs. We call this compensatory sweating. All patients have some degree of compensatory sweating and it ranges from mild to severe. A small percentage of patients (3-5 percent) experience more severe compensatory sweating. We consider it to be severe when it soaks through the clothing. It is a difficult situation especially in hot, humid days. Doctors have not determined who is most likely to experience severe compensatory sweating.

• #56 Hyperhidrosis Treatment FAQs | Mount Sinai – New York

  https://www.mountsinai.org/care/thoracic-surgery/services/hyperhidrosis/treatment-faqs

  Most patients who develop mild to moderate compensatory sweating say that they are not troubled by this extra perspiration. They find it better than the sweaty palms they had before the procedure. Patients who do develop severe compensatory sweating may have difficulty during hot humid weather or anxious situations. […] Some patients have a temporary recurrence of sweating on their palms three or four days after the operation. Usually this lasts no more than half a day.

• #57 Hyperhidrosis Treatment & Management: Medical Care, Surgical Care, Consultations

  https://emedicine.medscape.com/article/1073359-treatment

  In addition to pharmacologic therapy, other treatments include surgical sympathectomy, radiofrequency ablation, surgical excision of the affected areas, and subcutaneous liposuction. […] Sympathectomy has been used as a permanent effective treatment since 1920. […] Two surgical approaches are available: an open approach and a newer endoscopic approach. […] Endoscopic thoracic sympathectomy is an effective treatment for hyperhidrosis; in one study, immediate positive results occurred in 832 (98%) of 850 patients. […] Surgical excision of the affected area (identified with iodine starch testing) removes the appropriate sweat glands, thereby eliminating sweating. This technique is particularly useful in axillary hyperhidrosis. […] The treatment of axillary hyperhidrosis using the 1064-nm Nd-YAG laser was found to be effective and safe in a pilot trial. […] Subcutaneous liposuction is another means of removing the eccrine sweat glands responsible for axillary hyperhidrosis.

• #58 Treatment Overview – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/treatment-overview.html

  Additionally, healthcare providers and their patients are experimenting with combinations of treatments and getting good results. […] Underarm surgeries, such as liposuction, for excessive underarm sweating are being refined, but less invasive treatments should still be considered first. […] ETS surgery, although heavily advertised, is reserved for only certain severe cases of palmar hyperhidrosis (excessive sweating of the palms) that have not responded to any other treatment options or to combinations of treatments. […] Before considering ETS treatment, healthcare providers and their patients must fully consider and discuss the real risks of permanent damage and severe side effects including compensatory sweating. […] Everyones experience with this condition is different. […] So please be patient, explore all your options, explore combinations of options, adjust techniques, and work with your healthcare team to find the best treatments for your individual situation. […] Keep in mind, also, that research is still being conducted and new treatments, and new ways of using the current treatments, are being worked on.

• #59 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Another emerging treatment in axillary hyperhidrosis is fractionated microneedle radiofrequency. During this procedure, microneedles are placed 2 to 3 mm under the skin, and radiofrequency energy is applied. This therapy results in a decrease in the HDSS score of at least one point in nearly 80% of patients. […] Because hyperhidrosis is thought to be secondary to excessive sympathetic stimulation, endoscopic thoracic sympathectomy has been used to treat severe cases of hyperhidrosis. This procedure, which has evolved from an open procedure to an endoscopic one, involves cutting or clipping sympathetic nerves. Referral for endoscopic thoracic sympathectomy may be indicated when less invasive therapies are ineffective.

• #60 Hyperhidrosis

  https://www.aslms.org/for-the-public/treatments-using-lasers-and-energy-based-devices/hyperhidrosis

  Laser wavelengths that treat fat such as 1320 nm and 1440 nm have also been shown to treat overactive sweat glands. The treatment area is numbed and then exposed to laser energy in order to destroy many of the glands. […] Microwave devices such as miraDry work by destroying sweat glands with heat. […] Long term data for all three types of treatment is growing. Currently literature shows that all procedures have shown 90% patient satisfaction after 12 months. […] Current treatment for excessive sweating with either laser, microwave or ultrasound can provide excellent long term results.

• #61 Treatment Overview – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/treatment-overview.html

  If you suffer from excessive sweating, you may feel like you’ve tried everything. […] Please take some time to read through our information about all the treatments currently available for treating hyperhidrosis. […] As for medical treatments, here’s a brief overview (click through to specific treatment pages for more details): Treatments such as antiperspirants and iontophoresis have been improved and we now know how to make them more effective. […] More recent treatments, like miraDry, Botox injections, and lasers have started giving relief to those who never thought they’d find it. […] Newer additions are: Sofdra for underarms, a topical anticholinergic gel applied once per day at bedtime using a special applicator; Qbrexza for underarms, a topical anticholinergic medication self-applied at home daily using a medicated wipe (or „cloth”); and Brella SweatControl Patch is applied for 3 minutes in a healthcare provider’s office to treat axillary (underarm) excessive sweating (effects last about 2-4 months).

• #62 Hyperhidrosis: Diagnosis and treatment

  https://www.aad.org/public/diseases/a-z/hyperhidrosis-treatment

  If youre living with excessive sweating, treatment can improve your quality of life. Effective treatment begins with an accurate diagnosis, which tells you the type of hyperhidrosis you have. […] The goal of treatment is to: Reduce sweating so that it no longer interferes with your everyday life. […] There is no single best treatment for hyperhidrosis. Your dermatologist will customize your treatment plan to your needs. […] Patients diagnosed with primary hyperhidrosis (not due to a medication or medical condition) require treatment to control excessive sweating. […] To treat hyperhidrosis, your dermatologist will create an individualized treatment plan based on: The type of hyperhidrosis you have, Your symptoms, Where on your body you sweat heavily, Your preferences for treatment.

• #63 Hyperhidrosis: Diagnosis and treatment

  https://www.aad.org/public/diseases/a-z/hyperhidrosis-treatment

  If youre living with excessive sweating, treatment can improve your quality of life. Effective treatment begins with an accurate diagnosis, which tells you the type of hyperhidrosis you have. […] The goal of treatment is to: Reduce sweating so that it no longer interferes with your everyday life. […] There is no single best treatment for hyperhidrosis. Your dermatologist will customize your treatment plan to your needs. […] Patients diagnosed with primary hyperhidrosis (not due to a medication or medical condition) require treatment to control excessive sweating. […] To treat hyperhidrosis, your dermatologist will create an individualized treatment plan based on: The type of hyperhidrosis you have, Your symptoms, Where on your body you sweat heavily, Your preferences for treatment.

• #64 Hyperhidrosis: Diagnosis and treatment

  https://www.aad.org/public/diseases/a-z/hyperhidrosis-treatment

  If youre living with excessive sweating, treatment can improve your quality of life. Effective treatment begins with an accurate diagnosis, which tells you the type of hyperhidrosis you have. […] The goal of treatment is to: Reduce sweating so that it no longer interferes with your everyday life. […] There is no single best treatment for hyperhidrosis. Your dermatologist will customize your treatment plan to your needs. […] Patients diagnosed with primary hyperhidrosis (not due to a medication or medical condition) require treatment to control excessive sweating. […] To treat hyperhidrosis, your dermatologist will create an individualized treatment plan based on: The type of hyperhidrosis you have, Your symptoms, Where on your body you sweat heavily, Your preferences for treatment.

• #65 Treatment Overview – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/treatment-overview.html

  Additionally, healthcare providers and their patients are experimenting with combinations of treatments and getting good results. […] Underarm surgeries, such as liposuction, for excessive underarm sweating are being refined, but less invasive treatments should still be considered first. […] ETS surgery, although heavily advertised, is reserved for only certain severe cases of palmar hyperhidrosis (excessive sweating of the palms) that have not responded to any other treatment options or to combinations of treatments. […] Before considering ETS treatment, healthcare providers and their patients must fully consider and discuss the real risks of permanent damage and severe side effects including compensatory sweating. […] Everyones experience with this condition is different. […] So please be patient, explore all your options, explore combinations of options, adjust techniques, and work with your healthcare team to find the best treatments for your individual situation. […] Keep in mind, also, that research is still being conducted and new treatments, and new ways of using the current treatments, are being worked on.

• #66 Treatment Overview – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/treatment-overview.html

  Additionally, healthcare providers and their patients are experimenting with combinations of treatments and getting good results. […] Underarm surgeries, such as liposuction, for excessive underarm sweating are being refined, but less invasive treatments should still be considered first. […] ETS surgery, although heavily advertised, is reserved for only certain severe cases of palmar hyperhidrosis (excessive sweating of the palms) that have not responded to any other treatment options or to combinations of treatments. […] Before considering ETS treatment, healthcare providers and their patients must fully consider and discuss the real risks of permanent damage and severe side effects including compensatory sweating. […] Everyones experience with this condition is different. […] So please be patient, explore all your options, explore combinations of options, adjust techniques, and work with your healthcare team to find the best treatments for your individual situation. […] Keep in mind, also, that research is still being conducted and new treatments, and new ways of using the current treatments, are being worked on.

• #67 Hyperhidrosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459227/

  Hyperhidrosis is classified as primary and secondary, and the management and treatment can significantly differ. […] Several treatment options for hyperhidrosis include topical aluminum chloride and oral anticholinergic medications, which are sufficient in patients with mild to moderate disease. […] First-line therapy for hyperhidrosis includes over-the-counter aluminum chloride hexahydrate 20% for 3 to 4 nights, then nightly as needed. […] Recently, topical glycopyrronium tosylate (premoistened cloth containing 2.4% glycopyrronium solution) was approved for treating sweating. […] If a patient does not respond to topical treatment or has more generalized symptoms, oral anticholinergic medications should be considered, including oxybutynin 5 mg to 10 mg daily or topical glycopyrrolate 0.5% to 2.0%.

• #68 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  First-line treatment of all primary focal hyperhidrosis, regardless of severity, is topical 20% aluminum chloride (Drysol). This solution is applied nightly to the affected areas for six to eight hours until the HDSS score decreases, at which time the application interval can be lengthened to maintain sweat control. The aluminum salts cause an obstruction of the eccrine sweat glands and destruction of the secretory cells. […] For craniofacial hyperhidrosis, topical 2% glycopyrrolate (compounded by a pharmacy) may be considered first-line treatment. It has shown a 96% success rate (as measured by gravimetric chemical analysis and non-HDSS quality-of-life surveys) with minimal adverse effects (mild skin irritation), and can be applied once every two to three days. […] Botulinum toxin injection is the most studied hyperhidrosis treatment and demonstrates consistent improvement in HDSS scores and in sweat production as measured in the axillae and palms. It may be considered first- or second-line therapy for hyperhidrosis affecting the axillae, palms, soles, or face.

• #69 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  First-line treatment of all primary focal hyperhidrosis, regardless of severity, is topical 20% aluminum chloride (Drysol). This solution is applied nightly to the affected areas for six to eight hours until the HDSS score decreases, at which time the application interval can be lengthened to maintain sweat control. The aluminum salts cause an obstruction of the eccrine sweat glands and destruction of the secretory cells. […] For craniofacial hyperhidrosis, topical 2% glycopyrrolate (compounded by a pharmacy) may be considered first-line treatment. It has shown a 96% success rate (as measured by gravimetric chemical analysis and non-HDSS quality-of-life surveys) with minimal adverse effects (mild skin irritation), and can be applied once every two to three days. […] Botulinum toxin injection is the most studied hyperhidrosis treatment and demonstrates consistent improvement in HDSS scores and in sweat production as measured in the axillae and palms. It may be considered first- or second-line therapy for hyperhidrosis affecting the axillae, palms, soles, or face.

• #70 Hyperhidrosis Treatment & Management: Medical Care, Surgical Care, Consultations

  https://emedicine.medscape.com/article/1073359-treatment

  Iontophoresis was introduced in 1952 and consists of passing a direct current across the skin. […] Botulinum toxin injections are effective because of their anticholinergic effects at the neuromuscular junction and in the postganglionic sympathetic cholinergic nerves in the sweat glands. […] In palmar hyperhidrosis, 50 subepidermal injections of 2 mouse units per palm (total 100 mouse units per palm) results in anhydrosis lasting 4-12 months. […] Treatment of axillary hyperhidrosis with botulinum toxin type A reconstituted in lidocaine or in normal saline was described in a randomized, side-by-side, double-blind study. […] A 2008 study found botulinum toxin type A to be more effective than topical 20% aluminum chloride for the treatment of moderate-to-severe primary focal axillary hyperhidrosis.

• #71 Hyperhidrosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK459227/

  Hyperhidrosis is classified as primary and secondary, and the management and treatment can significantly differ. […] Several treatment options for hyperhidrosis include topical aluminum chloride and oral anticholinergic medications, which are sufficient in patients with mild to moderate disease. […] First-line therapy for hyperhidrosis includes over-the-counter aluminum chloride hexahydrate 20% for 3 to 4 nights, then nightly as needed. […] Recently, topical glycopyrronium tosylate (premoistened cloth containing 2.4% glycopyrronium solution) was approved for treating sweating. […] If a patient does not respond to topical treatment or has more generalized symptoms, oral anticholinergic medications should be considered, including oxybutynin 5 mg to 10 mg daily or topical glycopyrrolate 0.5% to 2.0%.

• #72 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Canadian guidelines recommend oral anticholinergics for treating primary hyperhidrosis with an HDSS score of 3 or 4 that does not resolve with topical aluminum chloride, onabotulinumtoxinA, or iontophoresis. The most commonly used oral anticholinergic medications are oxybutynin and glycopyrrolate. […] A newer, noninvasive local treatment of axillary hyperhidrosis uses microwave technology. The application of microwave energy destroys eccrine sweat glands by creating local heat, resulting in cellular thermolysis. This outpatient procedure is applied with a handheld transducer after mapping the axillae using the Minor starch-iodine test. Local anesthesia is required. This treatment results in a decrease in the HDSS score of at least one point in 94% of patients and at least two points in 55% of patients.

• #73 Treatment Overview – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/treatment-overview.html

  Additionally, healthcare providers and their patients are experimenting with combinations of treatments and getting good results. […] Underarm surgeries, such as liposuction, for excessive underarm sweating are being refined, but less invasive treatments should still be considered first. […] ETS surgery, although heavily advertised, is reserved for only certain severe cases of palmar hyperhidrosis (excessive sweating of the palms) that have not responded to any other treatment options or to combinations of treatments. […] Before considering ETS treatment, healthcare providers and their patients must fully consider and discuss the real risks of permanent damage and severe side effects including compensatory sweating. […] Everyones experience with this condition is different. […] So please be patient, explore all your options, explore combinations of options, adjust techniques, and work with your healthcare team to find the best treatments for your individual situation. […] Keep in mind, also, that research is still being conducted and new treatments, and new ways of using the current treatments, are being worked on.

• #74 Treatment of Hyperhidrosis | AAFP

  https://www.aafp.org/pubs/afp/issues/2011/0215/p464.html

  OnabotulinumtoxinA injections have been shown to be effective for at least 16 weeks. […] Aluminum chloride may be effective for treating hyperhidrosis. […] Iontophoresis may be effective for treating hyperhidrosis. […] The Canadian Hyperhidrosis Advisory Committee recommends topical aluminum chloride in a concentration of 20 to 50 percent for treating mild focal or multifocal hyperhidrosis. […] For patients with moderate to severe hyperhidrosis, the committee recommends starting treatment with topical aluminum chloride, and, if ineffective, trying iontophoresis or onabotulinumtoxinA injections. Further interventions, such as surgery, should be reserved for patients who do not respond to less invasive interventions.

• #75 Hyperhidrosis: Management Options | AAFP

  https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html

  Hyperhidrosis is excessive sweating that affects patients’ quality of life, resulting in social and work impairment and emotional distress. Primary hyperhidrosis is bilaterally symmetric, focal, excessive sweating of the axillae, palms, soles, or craniofacial region not caused by other underlying conditions. Secondary hyperhidrosis may be focal or generalized, and is caused by an underlying medical condition or medication use. The Hyperhidrosis Disease Severity Scale is a validated survey used to grade the tolerability of sweating and its impact on quality of life. The score can be used to guide treatment. Topical aluminum chloride solution is the initial treatment in most cases of primary focal hyperhidrosis. Topical glycopyrrolate is first-line treatment for craniofacial sweating. Botulinum toxin injection (onabotulinumtoxinA) is considered first- or second-line treatment for axillary, palmar, plantar, or craniofacial hyperhidrosis. Iontophoresis should be considered for treating hyperhidrosis of the palms and soles. Oral anticholinergics are useful adjuncts in severe cases of hyperhidrosis when other treatments fail. Local microwave therapy is a newer treatment option for axillary hyperhidrosis. Local surgery and endoscopic thoracic sympathectomy should be considered in severe cases of hyperhidrosis that have not responded to topical or medical therapies.

• #76 Hyperhidrosis: Diagnosis and treatment

  https://www.aad.org/public/diseases/a-z/hyperhidrosis-treatment

  The surgical treatments most often used to treat hyperhidrosis are: Sweat gland removal (underarms): Sweat glands can be removed from the underarms in several ways. […] Sympathectomy (palms, underarms): This surgery is performed in an operating room while the patient is under general anesthesia. […] With a dermatologists help, you dont need to live with excessive sweating. Your dermatologist knows how to create a treatment plan that can reduce hyperhidrosis.

• #77 Hyperhidrosis: Diagnosis and treatment

  https://www.aad.org/public/diseases/a-z/hyperhidrosis-treatment

  If youre living with excessive sweating, treatment can improve your quality of life. Effective treatment begins with an accurate diagnosis, which tells you the type of hyperhidrosis you have. […] The goal of treatment is to: Reduce sweating so that it no longer interferes with your everyday life. […] There is no single best treatment for hyperhidrosis. Your dermatologist will customize your treatment plan to your needs. […] Patients diagnosed with primary hyperhidrosis (not due to a medication or medical condition) require treatment to control excessive sweating. […] To treat hyperhidrosis, your dermatologist will create an individualized treatment plan based on: The type of hyperhidrosis you have, Your symptoms, Where on your body you sweat heavily, Your preferences for treatment.

• #78 Hyperhidrosis | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/skin-hair-and-nails/hyperhidrosis/

  Hyperhidrosis can be challenging to treat and it may take a while to find a treatment right for you. […] Doctors usually recommend starting with the least invasive treatment first, such as powerful antiperspirants. […] If this doesn’t help, you may be advised to try treatments such as iontophoresis (the affected area is treated with a weak electric current passed through water or a wet pad), botulinum toxin injections, and even surgery in a few cases. […] Hyperhidrosis is usually a long-term condition, but some people experience an improvement with time and the treatments available can often keep the problem under control. […] If lifestyle changes and treatment don’t work, your GP may refer you to a dermatologist (a specialist in treating skin conditions) for further treatment, such as iontophoresis, botulinum toxin or surgery.

• #79 Hyperhidrosis (excessive sweating)

  https://dermnetnz.org/topics/hyperhidrosis

  Hyperhidrosis is the name given to excessive and uncontrollable sweating. […] Hyperhidrosis is usually diagnosed clinically. Tests relate to the potential underlying cause of hyperhidrosis and are rarely necessary for primary hyperhidrosis. […] The treatment requires a long-term commitment. […] Botulinum toxin injections are approved for hyperhidrosis affecting the armpits. […] Overactive sweat glands in the armpits may be removed by several methods, usually under local anaesthetic. […] Division of the sympathetic spinal nerves by chemical or surgical endoscopic thoracic sympathectomy (ETS) may reduce sweating of face (T2 ganglion) or armpit and hand (T3 or T4 ganglion) but is reserved for the most severely affected individuals due to potential risks and complications. […] Localised primary hyperhidrosis tends to improve with age. The outlook for secondary localised or generalised hyperhidrosis depends on the cause. […] Several research projects are underway to find safer and more effective treatments for hyperhidrosis.

• #80 Treatment of Hyperhidrosis: An Update – PubMed

  https://pubmed.ncbi.nlm.nih.gov/35773437/

  Hyperhidrosis is a dermatosis presenting as pathologically excessive focal or generalized sweating. The stigmatizing nature of hyperhidrosis may cause patients to feel embarrassment and apprehension about their symptoms and experience a significant decrease in well-being. Severe cases of hyperhidrosis can also increase the risk of developing psychiatric and somatic comorbidities. Conventional non-surgical treatments of hyperhidrosis include aluminum salts, iontophoresis, botulinum toxin injections, and oral glycopyrronium. In recent years, new topical anticholinergic medications and devices have emerged that may improve the patients’ symptoms and even prevent the development of comorbidities. The treatment of hyperhidrosis can be a complex matter and may require the combination of several therapies. The purpose of this paper was to firstly review the literature on existing non-surgical treatment options for hyperhidrosis, and secondly provide a stepwise approach to investigating and treating patients with hyperhidrosis.

• #81 Treatment Overview – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/treatment-overview.html

  Additionally, healthcare providers and their patients are experimenting with combinations of treatments and getting good results. […] Underarm surgeries, such as liposuction, for excessive underarm sweating are being refined, but less invasive treatments should still be considered first. […] ETS surgery, although heavily advertised, is reserved for only certain severe cases of palmar hyperhidrosis (excessive sweating of the palms) that have not responded to any other treatment options or to combinations of treatments. […] Before considering ETS treatment, healthcare providers and their patients must fully consider and discuss the real risks of permanent damage and severe side effects including compensatory sweating. […] Everyones experience with this condition is different. […] So please be patient, explore all your options, explore combinations of options, adjust techniques, and work with your healthcare team to find the best treatments for your individual situation. […] Keep in mind, also, that research is still being conducted and new treatments, and new ways of using the current treatments, are being worked on.

• #82 Hyperhidrosis (excessive sweating)

  https://dermnetnz.org/topics/hyperhidrosis

  Hyperhidrosis is the name given to excessive and uncontrollable sweating. […] Hyperhidrosis is usually diagnosed clinically. Tests relate to the potential underlying cause of hyperhidrosis and are rarely necessary for primary hyperhidrosis. […] The treatment requires a long-term commitment. […] Botulinum toxin injections are approved for hyperhidrosis affecting the armpits. […] Overactive sweat glands in the armpits may be removed by several methods, usually under local anaesthetic. […] Division of the sympathetic spinal nerves by chemical or surgical endoscopic thoracic sympathectomy (ETS) may reduce sweating of face (T2 ganglion) or armpit and hand (T3 or T4 ganglion) but is reserved for the most severely affected individuals due to potential risks and complications. […] Localised primary hyperhidrosis tends to improve with age. The outlook for secondary localised or generalised hyperhidrosis depends on the cause. […] Several research projects are underway to find safer and more effective treatments for hyperhidrosis.

• #83 Treatment Overview – International Hyperhidrosis Society | Official Site

  https://www.sweathelp.org/hyperhidrosis-treatments/treatment-overview.html

  Additionally, healthcare providers and their patients are experimenting with combinations of treatments and getting good results. […] Underarm surgeries, such as liposuction, for excessive underarm sweating are being refined, but less invasive treatments should still be considered first. […] ETS surgery, although heavily advertised, is reserved for only certain severe cases of palmar hyperhidrosis (excessive sweating of the palms) that have not responded to any other treatment options or to combinations of treatments. […] Before considering ETS treatment, healthcare providers and their patients must fully consider and discuss the real risks of permanent damage and severe side effects including compensatory sweating. […] Everyones experience with this condition is different. […] So please be patient, explore all your options, explore combinations of options, adjust techniques, and work with your healthcare team to find the best treatments for your individual situation. […] Keep in mind, also, that research is still being conducted and new treatments, and new ways of using the current treatments, are being worked on.

• #84 Hyperhidrosis: Diagnosis and treatment

  https://www.aad.org/public/diseases/a-z/hyperhidrosis-treatment

  The surgical treatments most often used to treat hyperhidrosis are: Sweat gland removal (underarms): Sweat glands can be removed from the underarms in several ways. […] Sympathectomy (palms, underarms): This surgery is performed in an operating room while the patient is under general anesthesia. […] With a dermatologists help, you dont need to live with excessive sweating. Your dermatologist knows how to create a treatment plan that can reduce hyperhidrosis.

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