Hiperpotliwość
Epidemiologia

Hiperpotliwość (hyperhidrosis) to schorzenie charakteryzujące się nadmiernym wydzielaniem potu przekraczającym potrzeby termoregulacji, dotykające globalnie około 385 milionów osób, z częstością występowania szacowaną na 2-4% populacji. Epidemiologia jest zróżnicowana regionalnie: w USA częstość wynosi 2,8-4,8%, w Niemczech od 0,7% do 16,3% w zależności od metodologii, a w Azji, np. w Japonii, hiperpotliwość dłoniowo-podeszwowa występuje 20 razy częściej niż w innych grupach etnicznych. Hiperpotliwość pierwotna, stanowiąca ponad 90% przypadków, zwykle rozpoczyna się w dzieciństwie lub okresie dojrzewania, najczęściej dotyczy okolic pach (68%), dłoni (65%) i stóp (64%), a u 81% pacjentów występuje wieloogniskowo. Występuje bez wyraźnej predyspozycji płciowej, choć kobiety częściej zgłaszają problem lekarzowi. Genetyczne podłoże potwierdza obecność historii rodzinnej u 30-50% pacjentów oraz powiązanie z locus genu 14q11.2-q13.

  1. Epidemiologia hiperpotliwości – wprowadzenie
  2. Rozpowszechnienie hiperpotliwości na świecie
    1. Różnice między częstością samoraportowaną a zdiagnozowaną
  3. Charakterystyka demograficzna pacjentów z hiperpotliwością
    1. Rozkład wiekowy
    2. Tożsamość płciowa
    3. Różnice etniczne
  4. Wzorce rodzinne i predyspozycje genetyczne
  5. Typy i lokalizacje hiperpotliwości
    1. Zmiany w zależności od wieku
  6. Wpływ hiperpotliwości na jakość życia
    1. Czynniki ryzyka i implikacje społeczno-ekonomiczne
  7. Wyzwania w badaniach epidemiologicznych hiperpotliwości
  8. Regionalny przekrój epidemiologiczny
    1. Trendy w zapadalności
  9. Podsumowanie i przyszłe kierunki badań
    1. Kolejne rozdziały

Epidemiologia hiperpotliwości – wprowadzenie

Hiperpotliwość (łac. hyperhidrosis) to schorzenie charakteryzujące się nadmiernym wydzielaniem potu, przekraczającym fizjologiczne potrzeby termoregulacji organizmu. Epidemiologia tego zaburzenia jest różnie szacowana w zależności od metodologii badań, populacji oraz definicji samego schorzenia. Dostępne dane dotyczące rozpowszechnienia hiperpotliwości w populacji światowej były praktycznie nieistniejące aż do początku XXI wieku, a obecnie wciąż obserwuje się duże rozbieżności w raportowanych wskaźnikach12.

W ciągu ostatnich dwóch dekad opublikowano szereg badań epidemiologicznych, które pozwoliły lepiej zrozumieć rozpowszechnienie hiperpotliwości. Różnice w metodologii badań, kryteriach diagnostycznych oraz sposobie zbierania danych skutkują jednak znaczną rozbieżnością w uzyskanych wynikach – od 0,072% do nawet 16,3% w różnych populacjach34. Wymaga to ostrożnej interpretacji dostępnych danych.

Rozpowszechnienie hiperpotliwości na świecie

Globalne szacunki wskazują, że hiperpotliwość dotyka około 385 milionów ludzi na całym świecie12. Według Międzynarodowego Towarzystwa Hiperpotliwości (International Hyperhidrosis Society), ogólnoświatowa częstość występowania tego schorzenia mieści się w przedziale 2-4%, bez wyraźnej predyspozycji płciowej5.

W Stanach Zjednoczonych częstość występowania hiperpotliwości szacuje się na 2,8-4,8% populacji, co przekłada się na około 15,3 miliona Amerykanów12. Wcześniejsze badania wskazywały na niższy odsetek – około 2,8% (7,8 miliona), jednak nowsze dane sugerują, że problem może dotyczyć prawie dwukrotnie większej liczby osób3. Badanie Strutton i wsp. z 2004 roku, które było jednym z pierwszych opublikowanych badań z metodologicznym opisem, wykazało częstość występowania hiperpotliwości na poziomie 2,9%4.

W Europie występowanie hiperpotliwości również znacząco się różni w zależności od kraju i metodologii badań:

  • W Szwecji częstość występowania pierwotnej hiperpotliwości wynosiła 5,5%, z czego 1,4% stanowiły przypadki ciężkiej hiperpotliwości pierwotnej5
  • W Niemczech badanie z 2013 roku przeprowadzone wśród 14 336 pracowników z 52 firm wykazało najwyższą raportowaną częstość występowania – 16,3%, gdzie wszyscy pacjenci byli badani przez dermatologa6
  • Nowsze dane z Niemiec z 2020 roku wskazują, że 0,70% ubezpieczonych dorosłych miało zdiagnozowaną hiperpotliwość, co ekstrapolując na populację niemiecką odpowiada około 500 000 osób7

W Azji zaobserwowano jeszcze większe zróżnicowanie:

  • W niektórych rejonach Chin częstość występowania sięga 5,0%8
  • Badania z Szanghaju wykazały, że częstość występowania hiperpotliwości wśród pacjentów dermatologicznych wynosiła 14,5%9
  • W Japonii hiperpotliwość dłoniowo-podeszwowa występuje 20 razy częściej niż w innych grupach etnicznych10

W Brazylii badanie Lima i wsp. z 2015 roku wykazało częstość występowania hiperpotliwości na poziomie 14,76% wśród studentów medycyny11, a inne brazyjskie badanie z 2018 roku wykazało, że choć 2,07% badanych zgłaszało nadmierne pocenie się, to po ocenie medycznej rzeczywista częstość występowania pierwotnej hiperpotliwości wynosiła 0,93%1213.

Różnice między częstością samoraportowaną a zdiagnozowaną

Istotne różnice w częstości występowania hiperpotliwości zaobserwowano między przypadkami samoraportowanymi przez pacjentów a tymi potwierdzonymi przez lekarzy. Badanie z Danii wykazało, że 9,07% dawców krwi zgłaszało hiperpotliwość, podczas gdy tylko 0,23% miało diagnozę szpitalną12. Podobnie badanie brazylijskie pokazało, że po ocenie medycznej, tylko około połowa pacjentów zgłaszających nadmierne pocenie się rzeczywiście cierpiała na pierwotną hiperpotliwość3.

Te rozbieżności wskazują na trudności w diagnozowaniu hiperpotliwości oraz brak jednolitych kryteriów określających, co stanowi normalne pocenie się. Ponadto, wielu pacjentów nigdy nie zgłasza problemu lekarzowi – według badania amerykańskiego, jedynie 38% osób z hiperpotliwością konsultowało swój stan z lekarzem45.

Charakterystyka demograficzna pacjentów z hiperpotliwością

Rozkład wiekowy

Hiperpotliwość pierwotna najczęściej pojawia się w dzieciństwie lub w okresie dojrzewania i często towarzyszy pacjentom przez całe życie12. Dane dotyczące wieku początku choroby wskazują, że:

  • Większość przypadków hiperpotliwości dłoniowej i podeszwowej (odpowiednio 66% i 61%) zaczyna się w dzieciństwie (poniżej 12 roku życia)3
  • 36% pacjentów z pierwotną hiperpotliwością pachową zgłaszało początek objawów przed 12 rokiem życia4
  • W badaniu 850 pacjentów z hiperpotliwością dłoniową, pachową lub twarzy, 62% pacjentów zgłaszało, że objawy towarzyszyły im „odkąd pamiętają”, 33% wskazywało na początek w okresie dojrzewania, a tylko 5% zgłaszało pierwsze objawy w wieku dorosłym56

Najwyższa częstość występowania hiperpotliwości obserwowana jest w grupie wiekowej 18-39 lat (8,8%), a najniższa wśród dzieci/nastolatków (2,1%) oraz osób powyżej 65 roku życia (również 2,1%)78. Według niektórych autorów niższa częstość występowania w populacji osób starszych może wynikać z regresji choroby wraz z wiekiem9, jednak badanie z 2016 roku wykazało, że u 88% pacjentów objawy nie łagodnieją z wiekiem, ale raczej się nasilają lub pozostają na tym samym poziomie10.

Tożsamość płciowa

Większość badań nie wykazuje istotnej różnicy w częstości występowania hiperpotliwości między mężczyznami a kobietami123. Jednakże kobiety częściej zgłaszają ten problem lekarzowi45.

W bazach danych medycznych z USA i Wielkiej Brytanii około 60% zarejestrowanych przypadków dotyczyło kobiet67. Podobnie w niemieckim badaniu z 2020 roku, 61,6% osób z hiperpotliwością stanowiły kobiety8. Również w badaniu brazylijskim, po ocenie medycznej, proporcja kobiet z diagnozą pierwotnej hiperpotliwości znacząco wzrosła9.

Obserwuje się pewne różnice w lokalizacji nadmiernego pocenia się między płciami – u mężczyzn częściej dotyczy ono obszaru twarzy i głowy, podczas gdy u kobiet częściej występuje w okolicach pach10.

Różnice etniczne

Hiperpotliwość może dotykać wszystkich ras, jednak niektóre badania wskazują na różnice etniczne w jej występowaniu. Japończycy są dotknięci hiperpotliwością dłoniowo-podeszwową nawet 20 razy częściej niż inne grupy etniczne1. Niektóre doniesienia sugerują również częstsze występowanie hiperpotliwości dłoni i stóp u pacjentów pochodzenia japońsko-amerykańskiego2.

Dane epidemiologiczne dotyczące hiperpotliwości znacznie różnią się między krajami ze względu na różnice genetyczne, warunki środowiskowe (urbanizacja i narażenie na zanieczyszczenia środowiska), klimat oraz dostęp do opieki zdrowotnej3.

Wzorce rodzinne i predyspozycje genetyczne

Istnieją silne dowody na genetyczne podłoże hiperpotliwości pierwotnej. Około 30-50% pacjentów zgłasza występowanie tego schorzenia u innych członków rodziny, co sugeruje genetyczną predyspozycję123.

Nowsze dane z 2018 roku wskazują, że 18% pacjentów z hiperpotliwością zgłasza, że przynajmniej jeden członek najbliższej rodziny również cierpi na nadmierne pocenie się4. W badaniach pacjentów leczonych za pomocą endoskopowej sympatektomii piersiowej (ETS) historia rodzinna była obserwowana u 35-56% uczestników5.

Analiza agregacji rodzinnej hiperpotliwości wykazała, że 65% pacjentów z pierwotną hiperpotliwością zgłaszało historię rodzinną w porównaniu do braku historii rodzinnej w grupie kontrolnej. Na podstawie tych ustaleń stwierdzono, że allel choroby jest obecny u 5% populacji, z obserwowaną penetracją wynoszącą 25%6.

W 2006 roku badacze z Uniwersytetu Saga w Japonii zgłosili, że pierwotna hiperpotliwość dłoniowa wiąże się z locus genu 14q11.2-q137, co stanowi kolejny dowód na genetyczne podłoże tego schorzenia.

Typy i lokalizacje hiperpotliwości

Hiperpotliwość dzieli się na dwa główne typy:

  • Pierwotna hiperpotliwość – bez znanej przyczyny, często rozpoczynająca się w dzieciństwie lub okresie dojrzewania, zwykle ogniskowa
  • Wtórna hiperpotliwość – wynikająca z innego schorzenia lub przyjmowanych leków, często uogólniona

Ponad 90% przypadków hiperpotliwości stanowi typ pierwotny, z czego ponad połowa dotyczy okolic pach1. Pierwotna hiperpotliwość ogniskowa jest najczęściej wieloogniskowa, z 81% pacjentów zgłaszających trzy lub więcej miejsc nadmiernego pocenia się2.

Dane z niemieckiego badania z 2020 roku pokazują, że spośród pacjentów z hiperpotliwością:

  • 9,24% miało formę zlokalizowaną
  • 8,65% miało formę uogólnioną
  • 84,80% miało formę nieokreśloną3

Częstość występowania różnych typów pierwotnej hiperpotliwości w zależności od lokalizacji była raportowana w licznych badaniach. W badaniu z 2016 roku, obejmującym 1985 uczestników, hiperpotliwość pachowa była najbardziej rozpowszechniona (68%), następnie dłoniowa (65%) i podeszwowa (64%). Ponad 30% respondentów zgłaszało hiperpotliwość twarzoczaszkową, pachwinową lub podsutkową4.

Badanie opublikowane w Journal of Marine Medical Society (2024) wykazało, że w populacji indyjskiej najczęściej dotkniętym przez nadmierne pocenie się obszarem była okolica dłoniowo-podeszwowa (43,8% pacjentów), a drugim najczęściej dotkniętym obszarem były dłonie (36,3%)5.

W badaniach brazylijskich dotyczących epidemiologii hiperpotliwości zaobserwowano, że hiperpotliwość manifestuje się częściej w więcej niż jednym miejscu, a główną dolegliwością najbardziej wpływającą na pacjentów jest hiperpotliwość dłoniowa, która pojawia się już w okresie dojrzewania. Gdy występują dwa miejsca pocenia się, najczęstszą kombinacją jest dłoniowo-podeszwowa, a gdy występują trzy miejsca, najczęstszymi kombinacjami są: dłoniowo-podeszwowo-pachowa oraz pachowo-dłoniowo-podeszwowa6.

Zmiany w zależności od wieku

Lokalizacja hiperpotliwości może się różnić w zależności od wieku pacjenta. Hiperpotliwość zlokalizowana jest częstsza w młodszych grupach wiekowych (18-30 lat), podczas gdy starsze grupy wiekowe (70-80 lat) znacznie częściej cierpią na hiperpotliwość uogólnioną1.

Wpływ hiperpotliwości na jakość życia

Hiperpotliwość znacząco wpływa na jakość życia pacjentów, powodując emocjonalne, psychologiczne, społeczne i zawodowe upośledzenie1. Ponad jedna trzecia osób z hiperpotliwością pachową zgłasza, że stan ten jest trudny do zniesienia lub całkowicie nie do zniesienia i prawie zawsze zakłóca codzienne czynności2.

Badania wykazują, że hiperpotliwość negatywnie wpływa na codzienne życie, szczególnie na dobrostan emocjonalny, samoocenę, relacje międzyludzkie i wydajność zawodową3. Wpływ na jakość życia jest znaczący – badanie brazylijskie wykazało, że prawie 50% respondentów z pierwotną hiperpotliwością zgłaszało pogorszoną jakość życia45.

Mimo znaczącego wpływu na jakość życia, wielu pacjentów nie szuka pomocy medycznej. Nowsze badania (z 2016 i 2018 roku) pokazują, że:

  • 85% pacjentów czeka ponad 3 lata, aby omówić problem nadmiernego pocenia się z pracownikiem służby zdrowia
  • 50% czeka ponad 10 lat, aby to zrobić
  • 27% nigdy nie otrzymuje diagnozy6

Wśród pacjentów z hiperpotliwością, którzy nie otrzymali żadnego leczenia, 38,5% stwierdziło, że „nie są pewni dlaczego”7. Szacuje się, że występuje średnio 15-letnie opóźnienie w zgłaszaniu się pacjentów z hiperpotliwością do podstawowej opieki zdrowotnej8.

Czynniki ryzyka i implikacje społeczno-ekonomiczne

Badanie duńskich dawców krwi wykazało, że samoraportowana hiperpotliwość była związana z potencjalnymi czynnikami ryzyka, takimi jak palenie tytoniu (iloraz szans [OR] 1,17) i nadwaga (OR 1,72), oraz potencjalnymi implikacjami choroby, takimi jak bezrobocie (OR 1,60), krótsze wykształcenie (OR 0,76) i niższy dochód12.

Międzynarodowe Towarzystwo Hiperpotliwości (IHHS) donosi, że osoby z hiperpotliwością mają 300% większe ryzyko infekcji skórnych niż osoby nie doświadczające tej choroby3.

Koszty hospitalizacji okazały się najwyższe pod względem ekonomicznego obciążenia kosztami bezpośrednimi. Koszty pośrednie nadal nie są dobrze zbadane, ale niektóre publikacje donoszą o utracie produktywności i liczbie dni przed powrotem do pracy, co sugeruje, że hiperpotliwość może mieć negatywny wpływ społeczny4.

Wyzwania w badaniach epidemiologicznych hiperpotliwości

Istnieje kilka istotnych wyzwań w prowadzeniu badań epidemiologicznych dotyczących hiperpotliwości:

  • Brak jednolitych wytycznych określających, co dokładnie stanowi normalne pocenie się1
  • Różnice w metodologii badań, kryteriach diagnostycznych i metodach zbierania danych2
  • Niedostateczne zgłaszanie problemu przez pacjentów – mniej niż połowa osób dotkniętych hiperpotliwością omawia to ze swoim lekarzem3
  • Ograniczenia w analizie danych związane z tym, że istotna część osób nie szukających pomocy medycznej nie jest kodowana zgodnie z ICD-10 przez lekarza lub płaci za leczenie samodzielnie4

Badacze (Ro i współpracownicy) doszli do wniosku, że ponieważ wiele osób z hiperpotliwością niechętnie szuka leczenia, wcześniej raportowana częstość występowania może być „znacznie niedoszacowana”5.

Regionalny przekrój epidemiologiczny

Częstość występowania hiperpotliwości wykazuje znaczne zróżnicowanie regionalne, również w obrębie poszczególnych krajów:

Region/Kraj Częstość występowania Uwagi
USA 2,8-4,8% Około 15,3 miliona osób
Szwecja 5,5% 1,4% ciężka hiperpotliwość pierwotna
Niemcy 0,7-16,3% Znaczne różnice w zależności od metodologii badań
Wielka Brytania 1,0-1,6% Dane z baz opieki zdrowotnej
Chiny 2,08-18,4% 18,4% wśród pacjentów hospitalizowanych
Japonia wyższa Hiperpotliwość dłoniowo-podeszwowa 20x częstsza
Brazylia 0,93-14,76% Wyższe wskaźniki wśród studentów medycyny
Dania 0,23-9,07% 0,23% diagnoza szpitalna, 9,07% samoraportowana
Indie 2,5-3% 43,8% przypadków dotyczy obszaru dłoniowo-podeszwowego

W Niemczech, na poziomie krajów związkowych, najwyższą częstość występowania hiperpotliwości (standaryzowaną według wieku, płci i kraju związkowego) zaobserwowano w Saksonii-Anhalt (0,94%), Meklemburgii-Pomorzu Przednim (0,87%) i Brandenburgii (0,82%)1.

Trendy w zapadalności

Zapadalność (liczba nowych przypadków) na hiperpotliwość również różni się w zależności od regionu. Wahała się od 0,13% w Wielkiej Brytanii do 0,28% w Stanach Zjednoczonych, z wyższym wskaźnikiem wśród pacjentek płci żeńskiej12. W Niemczech w 2020 roku zapadalność wynosiła 0,35%3.

Populacyjne badanie przekrojowe epidemiologii chirurgicznej korekcji hiperpotliwości w 1216 pacjentów na przestrzeni 11 lat w Brazylii wykazało, że 65,29% pacjentów stanowiły kobiety, 66,2% było w wieku 20-39 lat, a 37,59% miało adresy zarejestrowane poza São Paulo. Zaobserwowano również tendencję spadkową w liczbie zabiegów na przestrzeni lat45.

Podsumowanie i przyszłe kierunki badań

Epidemiologia hiperpotliwości jest złożona i wciąż niedostatecznie poznana. Rozbieżności w raportowanych wskaźnikach częstości występowania wynikają z różnic metodologicznych, kryteriów diagnostycznych oraz niedostatecznego zgłaszania problemu przez pacjentów. Mimo to, dostępne dane wskazują, że hiperpotliwość jest schorzeniem relatywnie powszechnym, wieloogniskowym i przewlekłym, z początkiem w młodym wieku i wyraźnym powiązaniem genetycznym, jednak diagnoza i leczenie są często opóźnione o wiele lat1.

Przyszłe działania powinny obejmować wdrożenie programów edukacyjnych dla lekarzy, specjalistów medycznych i pacjentów w celu zwiększenia świadomości na temat tego schorzenia, prowadzenie dalszych badań o szerszym zakresie i większych populacjach pacjentów, oraz generowanie większej ilości danych dla regionów, dla których brakuje dokładnych informacji epidemiologicznych2.

Analiza danych z wielu źródeł łącząca dane pierwotne i wtórne będzie potrzebna dla uzyskania pełnego obrazu opieki zdrowotnej i epidemiologii hiperpotliwości3. Poprawa praktyk identyfikowania hiperpotliwości w warunkach klinicznych może zwiększyć czułość i swoistość przyszłych badań oraz poprawić charakterystykę i kwantyfikację populacyjnego obciążenia tą istotną chorobą4.

Mimo ograniczonych danych, dostępne dowody sugerują, że hiperpotliwość powoduje fizyczne, psychologiczne i ekonomiczne obciążenie w codziennym życiu pacjentów. Wprowadzenie nowych metod leczenia może poprawić środowisko medyczne hiperpotliwości i zmniejszyć obciążenie pacjentów56.

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  1. 18.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Hyperhidrosis prevalence and its impact on population – Hasimoto – Shanghai Chest
    https://shc.amegroups.org/article/view/5114/html
    Hyperhidrosis is a disorder characterized by excessive sweating which beyond the physiological need for body thermoregulation. The prevalence data available in the literature are practically nonexistent up to the beginning of the 21st century. The objective of this present study is to review the literature as a quest for studies that evaluated the prevalence of hyperhidrosis and its impact on the quality of life of individuals. The prevalence found in the articles varied from 0.072% to 16.3%. As to the impact on the quality of life, all articles have shown that such disorder affects in some way the life of the individuals. The data available in the literature regarding the prevalence of hyperhidrosis in the world population are practically nonexistent until the beginning of the 21st century, therefore up to some time ago little was known about the number of individuals bearing this disorder. The bibliographic review was done by using the PubMed database (until January 10th 2019). Sixteen articles (17-32) that evaluated the prevalence of hyperhidrosis were found in the research, 15 (18-32) of them were published from the 21st century. The prevalence of hyperhidrosis found in the articles ranged from 0.072% to 16.3%. The first citation found in the literature about the prevalence of hyperhidrosis is from 1977 (17). Adar et al. refers to a pilot epidemiological study, not published, carried out with young Israelis, where the reported incidence was from 0.6% to 1%. The first published work with methodological description was the one by Strutton et al. in 2004 (18). In this great American study, a formulated questionnaire was sent to 150,000 households aimed at identifying possible individuals who suffer from hyperhidrosis. The prevalence found was 2.9% (6,800 individuals) and the prevalence projected for the United States was 2.8% (7.8 million individuals). In 2007 China published two studies (19,20) about the prevalence of hyperhidrosis. The prevalence of palmar hyperhidrosis was 4.59%. The prevalence of palmar hyperhidrosis found in these three cities in the southeast of China was 4.36%. The two first Brazilian works were published in 2009 and in 2011, by Felini et al. (21) and Westphal et al. (22), respectively. The evaluation of such questionnaires revealed a 9% hyperhidrosis prevalence, the highest one published so far. The lowest prevalence of published hyperhidrosis was 0.072%, by Chu et al. (23). The information was collected in the National Health Insurance database of Taiwan. In 2013, Stefaniak et al. (24) conducted a work in Poland which included 253 students of medicine and dentistry. The prevalence found was 12.76% and the individuals did not have the diagnostic confirmed by a doctor. The highest prevalence published among all published papers was the one by Augustin et al. in 2013 (26). This study included 14,336 employees from 52 German companies. The prevalence found was 16.3% and all of the individuals were evaluated by a dermatologist. The third Brazilian work was published in 2015 by Lima et al. (27) and 447 students of the medicine course from two universities of the State of Sergipe were included. The prevalence found was 14.76%. A new study was published by the Chinese group in 2015 (28), this time involving 70,000 students. The prevalence found was 2.08% and the individuals had their diagnostic confirmed by a doctor. In 2016, with the objective of evaluating the prevalence of hyperhidrosis in different ethnic groups, a work was done by Liu et al. (29). The prevalence found was 14.6% in Shanghai and 12.3% in Vancouver. The last European published work was in 2016, by Shayesteh et al. (30). The prevalence of hyperhidrosis in this population was 5.5%. In 2016, Doolittle et al. (31) sent by e-mail an invitation to 275,904 people to participate in an online survey. The prevalence found was 4.8%. The most recent work about the prevalence of hyperhidrosis belongs to our group, published in 2018 (32). The work included 1,351 households, rounding up to 4,113 dwellers. At first 2.07% of the interviewees reported having hyperhidrosis, however, after the medical evaluation the prevalence dropped to 0.93%. The existing data of hyperhidrosis prevalence in the world population are well varied and questionable due to the heterogeneity of methodologies used in several studies. The scaling of the problem is important for the establishment of measures that take into consideration the identification, orientation and treatment, aimed at improving the quality of life of its patients.
  • #1 Hyperhidrosis Epidemiology Forecast 2034
    https://www.expertmarketresearch.com/epidemiology-reports/hyperhidrosis-epidemiology-forecast
    The International Hyperhidrosis Society reports that around 385 million people worldwide have hyperhidrosis, a condition characterized by excessive sweating. It is more common in younger people, affecting 8.8% of individuals aged 18 to 39. Hyperhidrosis epidemiology forecast indicates that hyperhidrosis often begins in early adulthood or adolescence. […] Expert Market Research’s Hyperhidrosis Epidemiology Forecast Report 2025-2034 offers comprehensive information on the prevalence and demographics of hyperhidrosis. It projects the future incidence and prevalence rates of hyperhidrosis across various populations. The study covers age, gender, and type as major determinants of the hyperhidrosis-affected population. The report highlights patterns in the prevalence of hyperhidrosis over time and projects future trends based on multiple variables.
  • #1 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    In the past, there was little data on the prevalence of primary hyperhidrosis (Hh). Recently, however, more studies have been published in the medical literature – with illuminating statistics: […] Researchers reported the prevalence of hyperhidrosis in the United States as 4.8%, representing approximately 15.3 million people. That’s almost twice as many people as previously believed and this makes Hh more common than autism, melanoma, psoriasis, and peanut allergies. In the study, the prevalence rate was shown to be highest among 18–39 year olds (8.8%) and lowest among children/adolescents (2.1%). […] A study showed that, in Sweden, prevalence of primary hyperhidrosis was 5.5% with severe, primary hyperhidrosis affecting 1.4% of the population. Secondary hyperhidrosis was observed in 14.8% of the study participants.
  • #1 Epidemiology of Hyperhidrosis in Danish Blood Donors | HTML | Acta Dermato-Venereologica
    https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3790
    Epidemiology of Hyperhidrosis in Danish Blood Donors […] The objectives of this retrospective cohort study were to estimate the prevalence of hyperhidrosis and to compare demographic, lifestyle, and socioeconomic parameters in blood donors with and without self-reported or hospital-diagnosed hyperhidrosis. Overall, 2,794 of 30,808 blood donors (9.07%; 95% confidence interval (95% CI) 8.759.40) had self-reported hyperhidrosis and 284 of 122,225 (0.23%; 95% CI 0.210.26) had hospital-diagnosed hyperhidrosis. Self-reported hyperhidrosis was associated with smoking (odds ratio (OR) 1.17; 95% CI 1.051.31), overweight (OR 1.72; 95% CI 1.581.87), unemployed (OR 1.60; 95% CI 1.242.08), short education (OR 0.76; 95% CI 0.640.90), and lower income (beta-coefficient 26,121; 95% CI 37,931, 14,311). Hospital-diagnosed hyperhidrosis did not differ from controls. Thus, self-reported hyperhidrosis was associated with potential hyperhidrosis risk factors (smoking, overweight) and disease implications (unemployment, low education level and income).
  • #1 Hyperhidrosis: Background, Pathophysiology, Etiology
    https://emedicine.medscape.com/article/1073359-overview
    In the United States and the United Kingdom, 1-1.6% of people have records reflecting hyperhidrosis. About 60% in both databases were women. […] In adolescents and young adults, an incidence rate of 0.6-1% is reported for hyperhidrosis. […] Palmoplantar hyperhidrosis occurs 20 times more frequently in the Japanese than in any other ethnic group. […] All races can be affected by hyperhidrosis; however, Japanese are reportedly affected more than 20 times more frequently than other ethnic groups. […] Both sexes can be affected by hyperhidrosis. […] Persons of all ages can be affected by hyperhidrosis. Localized hyperhidrosis, unlike generalized hyperhidrosis, usually begins in childhood or adolescence. In a study of 850 patients with palmar, axillary, or facial hyperhidrosis, 62% of patients reported that sweating began since before they could remember; 33%, since puberty; and 5%, during adulthood.
  • #1 Hyperhidrosis – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK459227/
    Hyperhidrosis affects approximately 3% of the United States population and is most common in patients between 20 to 60 years of age. No evidence shows that either men or women are at increased risk. The palmar region is the most commonly affected area. Hyperhidrosis affects all races, but data show that the Japanese are more affected than any other ethnic group. […] Studies have shown that the prevalence of this disorder is approximately 3% in the United States. Hyperhidrosis can result in emotional, psychological, social, and occupational impairment.
  • #1 Hyperhidrosis: Management Options | AAFP
    https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html
    Hyperhidrosis affects 1% to 3% of the U.S. population, yet less than one-half of those affected discuss this with their physician. More than 90% of hyperhidrosis cases are primary, and more than one-half of these cases affect the axillae. More than one-third of persons with axillary hyperhidrosis report that the condition is barely tolerable or completely intolerable, and it nearly always interferes with daily activities. Up to two-thirds of patients report a family history, suggesting a genetic predisposition. Although prevalence between sexes is roughly equal, women are more likely to report hyperhidrosis to their physician. […] Hyperhidrosis negatively impacts daily life, especially emotional well-being, self-esteem, interpersonal relationships, and occupational productivity. Although several tools have been developed to measure the impact of hyperhidrosis on quality of life, most are too complex to incorporate into office practice. The Hyperhidrosis Disease Severity Scale (HDSS) is a validated single-question survey with four grades of tolerability of sweating and impact on quality of life. This survey can estimate the effect on daily activities and response to treatment.
  • #1 Epidemiology and health care of hyperhidrosis in Germany: claims data analysis | BMJ Open
    https://bmjopen.bmj.com/content/14/8/e085862
    Data on the population-based epidemiology of hyperhidrosis (HH) are scarce. This study investigated the epidemiology and healthcare of HH in Germany. In 2020, 0.70% of insured adults were confirmed to have HH (mean age 59.5 years, SD 18.9, 61.6% female), with 9.24% having a localised form, 8.65% a generalised form and 84.80% an unspecified form. The incidence was 0.35%. Localised HH was more common in younger age groups (18 to 30 years), while older age groups (70 to 80 years) were significantly more likely to suffer from generalised HH. In 2020, 0.70% (CI 0.70 to 0.70; table 1) of insured adults were diagnosed with HH. Extrapolated to the German population, these rates correspond to 500 000 persons with HH in medical care. In 2020, 0.35% (CI 0.35 to 0.35) of insured adults developed new cases of HH. On a federal state level, the highest prevalence of HH (standardised by age, gender and federal state) was observed in Saxony-Anhalt (0.94%), Mecklenburg-Western Pomerania (0.87%) and Brandenburg (0.82%). In 2020 4.88% were identified as having a severe form of the condition. The current prevalence of 0.7% is lower than the international published literature with 1%9.7%. The present analyses show that the majority of patients are treated by general practitioners and internists. Additional primary studies are needed to specify the epidemiology of the disease related to the care situation of patients with HH in Germany. […] The analysis of HH in claims data is limited since a relevant proportion of persons who do not seek medical care is not coded according to ICD-10 by the physician or pay for the treatment themselves.
  • #1 Azthena logo with the word Azthena
    https://www.news-medical.net/health/Hyperhidrosis-Prognosis-and-Epidemiology.aspx
    It is difficult to say how many people develop hyperhidrosis as there are no guidelines to determine exactly what constitutes normal sweating, but estimates suggest that the worldwide prevalence is between 2% and 4%, without any particular gender predisposition. […] There are differences in prevalence globally, with one study, for example, having shown a prevalence of 2.9% in the US and up to 5.0% prevalence in certain areas of China.
  • #1 Hyperhidrosis Limits Patients’ Daily Functioning, Quality of Life Across Several Different Regions
    https://www.hcplive.com/view/hyperhidrosis-limits-patients-daily-functioning-quality-of-life-across-several-different-regions
    The incidence of hyperhidrosis was found to have exhibited variations from 0.13% in the UK to 0.28% in the USA, with a higher occurrence being seen among females. […] Likewise, the investigators reported that hyperhidrosis’s prevalence ranged from 2.8% 4.8% for the US population to 18.40% for Chinese inpatients, whereas the axillary hyperhidrosis’s prevalence fluctuated from 1.4% for the US population to 5.75% for Japanese employees and/or students. […] While limited evidence exists on the hyperhidrosis burden, particularly among those in Japan, it still was shown to be a substantial hindrance to patients’ overall daily functioning. […] Despite limited data, available evidence suggests that hyperhidrosis places physical, psychological, and economic burdens on the daily lives of individual patients, they wrote. The introduction of new treatments is expected to improve the medical environment of hyperhidrosis and reduce the burden on patients. […] Understanding both the nature and impact of hyperhidrosis is of highest importance in addressing its challenges.
  • #1 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    In the 2003 U.S. consumer survey (noted above), the average age at onset was 25 years, but varied with location of hyperhidrosis. […] Prevalence of the types of primary hyperhidrosis based on body location has been reported in numerous studies: […] In 2016, results from 1,985 survey participants showed that axillary hyperhidrosis was the most prevalent type of hyperhidrosis in the study sample (68%) followed by palmar (65%) and plantar (64%). […] More than 30% of survey respondents reported craniofacial, groin, or inframammary hyperhidrosis. […] It should be noted here, again, the primary focal Hh is most typically a multifocal disease. […] Key take-aways: primary Hh is relatively common, multifocal, and chronic with an onset in youth and an apparent genetic link — yet, diagnosis and treatment is often delayed for years.
  • #2 Hyperhidrosis prevalence and its impact on population – Hasimoto – Shanghai Chest
    https://shc.amegroups.org/article/view/5114
    Hyperhidrosis is a disorder characterized by excessive sweating which beyond the physiological need for body thermoregulation. The prevalence data available in the literature are practically nonexistent up to the beginning of the 21st century. The objective of this present study is to review the literature as a quest for studies that evaluated the prevalence of hyperhidrosis and its impact on the quality of life of individuals. During the search 16 articles were found which evaluated the prevalence of hyperhidrosis and out of these, 5 evaluated the impact in the disorder as to the quality of life. The prevalence found in the articles varied from 0.072% to 16.3%. As to the impact on the quality of life, all articles have shown that such disorder affects in some way the life of the individuals. […] Although the methodology is quite different among the studies and though some prevalence data are questionable, the undertaking of this kind of study is important for the scaling of the problem and the establishment of measures that seek the improvement of the quality of life of its patients.
  • #2 Hyperhidrosis Epidemiology Forecast 2034
    https://www.expertmarketresearch.com/epidemiology-reports/hyperhidrosis-epidemiology-forecast
    As per the International Hyperhidrosis Society, nearly 385 million people are affected by hyperhidrosis across the globe. […] Studies show that hyperhidrosis is significantly more common in younger individuals compared to the general population. It is estimated that about 8.8% of people between the ages of 18 and 39 experience this condition. This higher prevalence in younger adults suggests that hyperhidrosis often begins during adolescence or early adulthood. […] The hyperhidrosis epidemiology data and findings from the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section. […] According to a 2023 review published in the Journal of Dermatology, the incidence of hyperhidrosis varied from 0.13% in the United Kingdom to 0.28% in the USA, with females showing higher rates.
  • #2 Hyperhidrosis and Its Impact on Those Living With It
    https://www.ajmc.com/view/hyperhidrosis-and-its-impact–on-those-living-with-it
    Hyperhidrosis affects approximately 4.8% of Americans. […] Primary hyperhidrosis reportedly affects 4.8% of Americans, or approximately 15.3 million individuals. […] Because it is often underreported and underdiagnosed, the true prevalence rates may be higher. […] It primarily affects younger adults aged 18 to 39 years. […] Rates are lowest among those 65 years and older, young children, and adolescents. […] It is speculated that lower prevalence among the elderly population is due to disease regression over time. […] Incidence rates do not appear to differ between genders. […] However, men may be more likely to be affected in craniofacial areas, although women are more likely to be affected in axillae areas. […] Some literature suggests a possible racial difference in the prevalence of primary hyperhidrosis, with more Japanese American patients affected by hyperhidrosis in the palms and soles.
  • #2 Epidemiology of Hyperhidrosis in Danish Blood Donors | HTML | Acta Dermato-Venereologica
    https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3790
    Overall, 2,794 of 30,808 blood donors had moderate-to-severe self-reported HH, which implied a prevalence of 9.07% (95% confidence interval (95% CI) 8.759.40). In contrast, 284 of 122,225 blood donors had hospital-diagnosed HH, which equated to a prevalence of 0.23% (95% CI 0.210.26). Self-reported HH was associated with overweight, smoking, reduced income, unemployed vs working and lower probability of short education vs high school. Hospital-diagnosed HH was not associated with any of the analysed parameters. […] The prevalence of hospital-diagnosed HH is clearly lower than the prevalence of self-reported HH. Self-reported HH is associated with potential HH risk factors (i.e. smoking and overweight) and potential disease implications (i.e. unemployment, low education level and income). In contrast, hospital-diagnosed HH does not differ from controls on these parameters.
  • #2 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    A series of studies on patients treated by endoscopic thoracic sympathectomy (ETS) reported a family history in 35% and 56% of participants. […] A study of the familial aggregation of hyperhidrosis also suggested that the disorder may be more common than previously thought. […] When family history was analyzed in a group of patients with primary hyperhidrosis, 65% of patients reported a family history compared to no family history in controls. […] On the basis of these findings, the disease allele is present in 5% of the population, with an observed penetrance of 25%. […] The researchers (Ro and colleagues) concluded that because many of those with hyperhidrosis are reluctant to seek treatment, the previously reported incidence may be “a gross underestimation.” […] Focal primary hyperhidrosis usually has an onset during childhood or adolescence.
  • #2 Hyperhidrosis: Background, Pathophysiology, Etiology
    https://emedicine.medscape.com/article/1073359-overview
    In the United States and the United Kingdom, 1-1.6% of people have records reflecting hyperhidrosis. About 60% in both databases were women. […] In adolescents and young adults, an incidence rate of 0.6-1% is reported for hyperhidrosis. […] Palmoplantar hyperhidrosis occurs 20 times more frequently in the Japanese than in any other ethnic group. […] All races can be affected by hyperhidrosis; however, Japanese are reportedly affected more than 20 times more frequently than other ethnic groups. […] Both sexes can be affected by hyperhidrosis. […] Persons of all ages can be affected by hyperhidrosis. Localized hyperhidrosis, unlike generalized hyperhidrosis, usually begins in childhood or adolescence. In a study of 850 patients with palmar, axillary, or facial hyperhidrosis, 62% of patients reported that sweating began since before they could remember; 33%, since puberty; and 5%, during adulthood.
  • #2 Hyperhidrosis – Wikipedia
    https://en.wikipedia.org/wiki/Hyperhidrosis
    It is estimated that the incidence of focal hyperhidrosis may be as high as 2.8% of the population of the United States. […] It affects men and women equally, and most commonly occurs among people aged 25-64 years, though some may have been affected since early childhood. […] About 30-50% of people have another family member affected, implying a genetic predisposition. […] In 2006, researchers at Saga University in Japan reported that primary palmar hyperhidrosis maps to gene locus 14q11.2-q13.
  • #2 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    Research results found that the prevalence of primary hyperhidrosis among dermatology outpatients in Shanghai was 14.5% and in Vancouver was 12.3%. […] Data showed that multifocal hyperhidrosis is common with 81% of patients reporting three or more hyperhidrotic sites. […] Data presented as an abstract on „pediatric breaking news” showed that 17.1% of teens surveyed experience excessive, uncontrollable sweating based on published diagnostic criteria. […] Hyperhidrosis (extreme, uncontrollable sweating affecting 4.8% of people) is often misunderstood, misrepresented and mismanaged, but for the past 15 years the International Hyperhidrosis Society has been bringing the full range of stakeholders to the table to transform missed opportunities into an impactful mission. […] The above statistics are key updates on older research, which has been frequently cited:
  • #2 Hyperhidrosis: Management Options | AAFP
    https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html
    Hyperhidrosis affects 1% to 3% of the U.S. population, yet less than one-half of those affected discuss this with their physician. More than 90% of hyperhidrosis cases are primary, and more than one-half of these cases affect the axillae. More than one-third of persons with axillary hyperhidrosis report that the condition is barely tolerable or completely intolerable, and it nearly always interferes with daily activities. Up to two-thirds of patients report a family history, suggesting a genetic predisposition. Although prevalence between sexes is roughly equal, women are more likely to report hyperhidrosis to their physician. […] Hyperhidrosis negatively impacts daily life, especially emotional well-being, self-esteem, interpersonal relationships, and occupational productivity. Although several tools have been developed to measure the impact of hyperhidrosis on quality of life, most are too complex to incorporate into office practice. The Hyperhidrosis Disease Severity Scale (HDSS) is a validated single-question survey with four grades of tolerability of sweating and impact on quality of life. This survey can estimate the effect on daily activities and response to treatment.
  • #2 Epidemiology of Hyperhidrosis in Danish Blood Donors | Abstract | Acta Dermato-Venereologica
    https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-3790
    The risk factors and disease implications of hyperhidrosis are unknown. The objectives of this retrospective cohort study were to estimate the prevalence of hyperhidrosis and to compare demographic, lifestyle, and socioeconomic parameters in blood donors with and without self-reported or hospital-diagnosed hyperhidrosis. Overall, 2,794 of 30,808 blood donors (9.07%; 95% confidence interval (95% CI) 8.759.40) had self-reported hyperhidrosis and 284 of 122,225 (0.23%; 95% CI 0.210.26) had hospital-diagnosed hyperhidrosis. Self-reported hyperhidrosis was associated with smoking (odds ratio (OR) 1.17; 95% CI 1.051.31), overweight (OR 1.72; 95% CI 1.581.87), unemployed (OR 1.60; 95% CI 1.242.08), short education (OR 0.76; 95% CI 0.640.90), and lower income (beta-coefficient 26,121; 95% CI 37,931, 14,311). Hospital-diagnosed hyperhidrosis did not differ from controls. Thus, self-reported hyperhidrosis was associated with potential hyperhidrosis risk factors (smoking, overweight) and disease implications (unemployment, low education level and income).
  • #2 Hyperhidrosis prevalence and its impact on population – Hasimoto – Shanghai Chest
    https://shc.amegroups.org/article/view/5114/html
    Hyperhidrosis is a disorder characterized by excessive sweating which beyond the physiological need for body thermoregulation. The prevalence data available in the literature are practically nonexistent up to the beginning of the 21st century. The objective of this present study is to review the literature as a quest for studies that evaluated the prevalence of hyperhidrosis and its impact on the quality of life of individuals. The prevalence found in the articles varied from 0.072% to 16.3%. As to the impact on the quality of life, all articles have shown that such disorder affects in some way the life of the individuals. The data available in the literature regarding the prevalence of hyperhidrosis in the world population are practically nonexistent until the beginning of the 21st century, therefore up to some time ago little was known about the number of individuals bearing this disorder. The bibliographic review was done by using the PubMed database (until January 10th 2019). Sixteen articles (17-32) that evaluated the prevalence of hyperhidrosis were found in the research, 15 (18-32) of them were published from the 21st century. The prevalence of hyperhidrosis found in the articles ranged from 0.072% to 16.3%. The first citation found in the literature about the prevalence of hyperhidrosis is from 1977 (17). Adar et al. refers to a pilot epidemiological study, not published, carried out with young Israelis, where the reported incidence was from 0.6% to 1%. The first published work with methodological description was the one by Strutton et al. in 2004 (18). In this great American study, a formulated questionnaire was sent to 150,000 households aimed at identifying possible individuals who suffer from hyperhidrosis. The prevalence found was 2.9% (6,800 individuals) and the prevalence projected for the United States was 2.8% (7.8 million individuals). In 2007 China published two studies (19,20) about the prevalence of hyperhidrosis. The prevalence of palmar hyperhidrosis was 4.59%. The prevalence of palmar hyperhidrosis found in these three cities in the southeast of China was 4.36%. The two first Brazilian works were published in 2009 and in 2011, by Felini et al. (21) and Westphal et al. (22), respectively. The evaluation of such questionnaires revealed a 9% hyperhidrosis prevalence, the highest one published so far. The lowest prevalence of published hyperhidrosis was 0.072%, by Chu et al. (23). The information was collected in the National Health Insurance database of Taiwan. In 2013, Stefaniak et al. (24) conducted a work in Poland which included 253 students of medicine and dentistry. The prevalence found was 12.76% and the individuals did not have the diagnostic confirmed by a doctor. The highest prevalence published among all published papers was the one by Augustin et al. in 2013 (26). This study included 14,336 employees from 52 German companies. The prevalence found was 16.3% and all of the individuals were evaluated by a dermatologist. The third Brazilian work was published in 2015 by Lima et al. (27) and 447 students of the medicine course from two universities of the State of Sergipe were included. The prevalence found was 14.76%. A new study was published by the Chinese group in 2015 (28), this time involving 70,000 students. The prevalence found was 2.08% and the individuals had their diagnostic confirmed by a doctor. In 2016, with the objective of evaluating the prevalence of hyperhidrosis in different ethnic groups, a work was done by Liu et al. (29). The prevalence found was 14.6% in Shanghai and 12.3% in Vancouver. The last European published work was in 2016, by Shayesteh et al. (30). The prevalence of hyperhidrosis in this population was 5.5%. In 2016, Doolittle et al. (31) sent by e-mail an invitation to 275,904 people to participate in an online survey. The prevalence found was 4.8%. The most recent work about the prevalence of hyperhidrosis belongs to our group, published in 2018 (32). The work included 1,351 households, rounding up to 4,113 dwellers. At first 2.07% of the interviewees reported having hyperhidrosis, however, after the medical evaluation the prevalence dropped to 0.93%. The existing data of hyperhidrosis prevalence in the world population are well varied and questionable due to the heterogeneity of methodologies used in several studies. The scaling of the problem is important for the establishment of measures that take into consideration the identification, orientation and treatment, aimed at improving the quality of life of its patients.
  • #2 Hyperhidrosis Limits Patients’ Daily Functioning, Quality of Life Across Several Different Regions
    https://www.consultantlive.com/view/hyperhidrosis-limits-patients-daily-functioning-quality-of-life-across-several-different-regions
    The incidence of hyperhidrosis was found to have exhibited variations from 0.13% in the UK to 0.28% in the USA, with a higher occurrence being seen among females. […] Likewise, the investigators reported that hyperhidrosis prevalence ranged from 2.8% 4.8% for the US population to 18.40% for Chinese inpatients, whereas the axillary hyperhidrosis prevalence fluctuated from 1.4% for the US population to 5.75% for Japanese employees and/or students. […] While limited evidence exists on the hyperhidrosis burden, particularly among those in Japan, it still was shown to be a substantial hindrance to patients’ overall daily functioning. […] Despite limited data, available evidence suggests that hyperhidrosis places physical, psychological, and economic burdens on the daily lives of individual patients, they wrote. The introduction of new treatments is expected to improve the medical environment of hyperhidrosis and reduce the burden on patients. […] Understanding both the nature and impact of hyperhidrosis is of highest importance in addressing its challenges.
  • #2 Hyperhidrosis Disease Burden Requires Further Understanding
    https://www.dermatologytimes.com/view/hyperhidrosis-disease-burden-requires-further-understanding
    The cost of hospitalizations was found to be the highest in terms of economic burden of direct costs. […] Indirect costs are still not well understood, but despite this, 3 publications reported on productivity loss and the number of days prior to returning to work, which suggested that hyperhidrosis might have a negative social impact. […] This is the first comprehensive TLR study on hyperhidrosis including the epidemiology and disease burden of hyperhidrosis throughout regions to date, the authors noted. […] Future actions should include implementation of educational programs for physicians, medical specialists, and patients to raise awareness of the condition; the conduct of further studies with larger scope and bigger patient populations; and the generation of more evidence for Japan, concluded the authors.
  • #3 Hyperhidrosis prevalence and its impact on population – Hasimoto – Shanghai Chest
    https://shc.amegroups.org/article/view/5114/html
    Hyperhidrosis is a disorder characterized by excessive sweating which beyond the physiological need for body thermoregulation. The prevalence data available in the literature are practically nonexistent up to the beginning of the 21st century. The objective of this present study is to review the literature as a quest for studies that evaluated the prevalence of hyperhidrosis and its impact on the quality of life of individuals. The prevalence found in the articles varied from 0.072% to 16.3%. As to the impact on the quality of life, all articles have shown that such disorder affects in some way the life of the individuals. The data available in the literature regarding the prevalence of hyperhidrosis in the world population are practically nonexistent until the beginning of the 21st century, therefore up to some time ago little was known about the number of individuals bearing this disorder. The bibliographic review was done by using the PubMed database (until January 10th 2019). Sixteen articles (17-32) that evaluated the prevalence of hyperhidrosis were found in the research, 15 (18-32) of them were published from the 21st century. The prevalence of hyperhidrosis found in the articles ranged from 0.072% to 16.3%. The first citation found in the literature about the prevalence of hyperhidrosis is from 1977 (17). Adar et al. refers to a pilot epidemiological study, not published, carried out with young Israelis, where the reported incidence was from 0.6% to 1%. The first published work with methodological description was the one by Strutton et al. in 2004 (18). In this great American study, a formulated questionnaire was sent to 150,000 households aimed at identifying possible individuals who suffer from hyperhidrosis. The prevalence found was 2.9% (6,800 individuals) and the prevalence projected for the United States was 2.8% (7.8 million individuals). In 2007 China published two studies (19,20) about the prevalence of hyperhidrosis. The prevalence of palmar hyperhidrosis was 4.59%. The prevalence of palmar hyperhidrosis found in these three cities in the southeast of China was 4.36%. The two first Brazilian works were published in 2009 and in 2011, by Felini et al. (21) and Westphal et al. (22), respectively. The evaluation of such questionnaires revealed a 9% hyperhidrosis prevalence, the highest one published so far. The lowest prevalence of published hyperhidrosis was 0.072%, by Chu et al. (23). The information was collected in the National Health Insurance database of Taiwan. In 2013, Stefaniak et al. (24) conducted a work in Poland which included 253 students of medicine and dentistry. The prevalence found was 12.76% and the individuals did not have the diagnostic confirmed by a doctor. The highest prevalence published among all published papers was the one by Augustin et al. in 2013 (26). This study included 14,336 employees from 52 German companies. The prevalence found was 16.3% and all of the individuals were evaluated by a dermatologist. The third Brazilian work was published in 2015 by Lima et al. (27) and 447 students of the medicine course from two universities of the State of Sergipe were included. The prevalence found was 14.76%. A new study was published by the Chinese group in 2015 (28), this time involving 70,000 students. The prevalence found was 2.08% and the individuals had their diagnostic confirmed by a doctor. In 2016, with the objective of evaluating the prevalence of hyperhidrosis in different ethnic groups, a work was done by Liu et al. (29). The prevalence found was 14.6% in Shanghai and 12.3% in Vancouver. The last European published work was in 2016, by Shayesteh et al. (30). The prevalence of hyperhidrosis in this population was 5.5%. In 2016, Doolittle et al. (31) sent by e-mail an invitation to 275,904 people to participate in an online survey. The prevalence found was 4.8%. The most recent work about the prevalence of hyperhidrosis belongs to our group, published in 2018 (32). The work included 1,351 households, rounding up to 4,113 dwellers. At first 2.07% of the interviewees reported having hyperhidrosis, however, after the medical evaluation the prevalence dropped to 0.93%. The existing data of hyperhidrosis prevalence in the world population are well varied and questionable due to the heterogeneity of methodologies used in several studies. The scaling of the problem is important for the establishment of measures that take into consideration the identification, orientation and treatment, aimed at improving the quality of life of its patients.
  • #3 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    A consumer survey of a nationally representative sample of 150,000 households in the U.S. screened for the presence of hyperhidrosis. Results showed that the prevalence of hyperhidrosis in the U.S. was 2.8% (7.8 million Americans). Of those with hyperhidrosis, only 38% consulted their physician about their excessive sweating. […] Recent research (from 2016 and 2018) expands upon the above older data regarding long delays among sufferers in discussing Hh with a healthcare professional (HCP) and in receiving care: 85% waiting 3+ years to discuss excessive sweating with an HCP and 50% waiting 10+ years to do so. […] 27% never receiving diagnosis. […] Among Hh sufferers who had not received any hyperhidrosis treatment, 38.5% said they were „not sure why not.” […] Recent data (2018) found that 18% of Hh sufferers report an immediate family member also suffering from excessive sweating.
  • #3 SciELO Brasil – Hyperhidrosis: prevalence and impact on quality of life Hyperhidrosis: prevalence and impact on quality of life
    https://www.scielo.br/j/jbpneu/a/gxS3VxQSW3j7hX5MkLXDxqz/
    Objective: To determine the prevalence of primary hyperhidrosis in the city of Botucatu, Brazil, and to evaluate how this disorder affects the quality of life in those suffering from it. […] A total of 4,133 residents, in 1,351 households, were surveyed. Excessive sweating was reported by 85 residents (prevalence = 2.07%), of whom 51 (60%) were female. […] Although the prevalence of self-reported excessive sweating was greater than 2%, the actual prevalence of primary hyperhidrosis in our sample was 0.93% and nearly 50% of the respondents with primary hyperhidrosis reported impaired quality of life. […] There are few data on the worldwide prevalence of hyperhidrosis, reported values ranging from 0.072% to 9%. […] In our study, the prevalence of hyperhidrosis after the application of a questionnaire by trained interviewers was above 2%, as observed by Strutton et al. However, after medical evaluation, 25% of the patients that reported excessive sweating actually showed normal sweating and 30% had SH. Consequently, more than half of the subjects that reported excessive sweating did not actually have PH. Therefore, after medical evaluation, the estimated prevalence of PH decreased to less than 1%.
  • #3 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    Data published in 2016 found that: 1) the majority of palmar and plantar (66% and 61%, respectively) primary hyperhidrosis patients reported childhood onset (less than 12 years). 2) 36% of respondents reported that their primary axillary hyperhidrosis started before the age of 12 years. […] This 2016 study also showed that hyperhidrosis is often a lifelong struggle with symptom severity FAILING to lessen with age — 88% reported that symptoms have become worse or stayed the same over time. […] In a series of Taiwanese patients with palmar hyperhidrosis (1997), 75% had childhood onset, with the remainder presenting during puberty. […] In a study of 850 patients (2002) with palmar, axillary, or facial hyperhidrosis, 62% said they had the symptoms “as long as they could remember,” 33% said the onset occurred during puberty, and 5% reported their first symptoms as adults.
  • #3 Hyperhidrosis – Wikipedia
    https://en.wikipedia.org/wiki/Hyperhidrosis
    It is estimated that the incidence of focal hyperhidrosis may be as high as 2.8% of the population of the United States. […] It affects men and women equally, and most commonly occurs among people aged 25-64 years, though some may have been affected since early childhood. […] About 30-50% of people have another family member affected, implying a genetic predisposition. […] In 2006, researchers at Saga University in Japan reported that primary palmar hyperhidrosis maps to gene locus 14q11.2-q13.
  • #3 Palmar Hyperhidrosis Epidemiology Forecast 2034
    https://www.expertmarketresearch.com/epidemiology-reports/palmar-hyperhidrosis-epidemiology-forecast
    The palmar hyperhidrosis epidemiology section offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. Expert Market Research provides both current and predicted trends for palmar hyperhidrosis by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for palmar hyperhidrosis and their trends. The data is broken down into specific categories, such as the total diagnosed cases across different age groups and patient pools. […] Around 385 million individuals worldwide are living with hyperhidrosis including palmar hyperhidrosis, according to the International Hyperhidrosis Society. […] The epidemiology of palmar hyperhidrosis varies significantly between countries due to differences in genetic factors, environmental conditions (urbanization and exposure to environmental pollutants), climate, and healthcare access. A study published in the Journal of Marine Medical Society (2024) found that palmar hyperhidrosis affected 36.3% of the total cases in Indian patients, making it the second most common type after palmoplantar hyperhidrosis (43.8%).
  • #3 Epidemiology – Primary Care Notebook
    https://primarycarenotebook.com/pages/paediatrics/hyperhydrosis/epidemiology
    The prevalence of hyperhidrosis is reported to be around 1%. This figure is thought to be much higher since the majority of cases are not reported to primary care. […] According to a large American national survey, only 38% of patients with a primary pattern of symptoms had consulted a health professional. […] It is estimated that there is a 15 year delay in presentation of patients with hyperhidrosis to primary care. […] In 30% to 50% of cases of primary hyperhidrosis, a family history is reported.
  • #3 Epidemiology and health care of hyperhidrosis in Germany: claims data analysis | BMJ Open
    https://bmjopen.bmj.com/content/14/8/e085862
    Data on the population-based epidemiology of hyperhidrosis (HH) are scarce. This study investigated the epidemiology and healthcare of HH in Germany. In 2020, 0.70% of insured adults were confirmed to have HH (mean age 59.5 years, SD 18.9, 61.6% female), with 9.24% having a localised form, 8.65% a generalised form and 84.80% an unspecified form. The incidence was 0.35%. Localised HH was more common in younger age groups (18 to 30 years), while older age groups (70 to 80 years) were significantly more likely to suffer from generalised HH. In 2020, 0.70% (CI 0.70 to 0.70; table 1) of insured adults were diagnosed with HH. Extrapolated to the German population, these rates correspond to 500 000 persons with HH in medical care. In 2020, 0.35% (CI 0.35 to 0.35) of insured adults developed new cases of HH. On a federal state level, the highest prevalence of HH (standardised by age, gender and federal state) was observed in Saxony-Anhalt (0.94%), Mecklenburg-Western Pomerania (0.87%) and Brandenburg (0.82%). In 2020 4.88% were identified as having a severe form of the condition. The current prevalence of 0.7% is lower than the international published literature with 1%9.7%. The present analyses show that the majority of patients are treated by general practitioners and internists. Additional primary studies are needed to specify the epidemiology of the disease related to the care situation of patients with HH in Germany. […] The analysis of HH in claims data is limited since a relevant proportion of persons who do not seek medical care is not coded according to ICD-10 by the physician or pay for the treatment themselves.
  • #3 Hyperhidrosis: Management Options | AAFP
    https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html
    Hyperhidrosis affects 1% to 3% of the U.S. population, yet less than one-half of those affected discuss this with their physician. More than 90% of hyperhidrosis cases are primary, and more than one-half of these cases affect the axillae. More than one-third of persons with axillary hyperhidrosis report that the condition is barely tolerable or completely intolerable, and it nearly always interferes with daily activities. Up to two-thirds of patients report a family history, suggesting a genetic predisposition. Although prevalence between sexes is roughly equal, women are more likely to report hyperhidrosis to their physician. […] Hyperhidrosis negatively impacts daily life, especially emotional well-being, self-esteem, interpersonal relationships, and occupational productivity. Although several tools have been developed to measure the impact of hyperhidrosis on quality of life, most are too complex to incorporate into office practice. The Hyperhidrosis Disease Severity Scale (HDSS) is a validated single-question survey with four grades of tolerability of sweating and impact on quality of life. This survey can estimate the effect on daily activities and response to treatment.
  • #3 Hyperhidrosis and Its Impact on Those Living With It
    https://www.ajmc.com/view/hyperhidrosis-and-its-impact–on-those-living-with-it
    Hyperhidrosis negatively affects QOL and, as such, numerous QOL assessment tools are used to evaluate the condition. […] To date, many QOL impact studies have been completed outside of the United States, but it is likely the results represent QOL in US patients. […] The International Hyperhidrosis Society (IHHS) reports that those with hyperhidrosis have a 300% greater risk of skin infections than those not experiencing the disease. […] It is imperative that healthcare practitioners understand the epidemiology and impact this disease has on individuals.
  • #3 Epidemiology of hyperhidrosis in 2 population-based health care databases
    https://ouci.dntb.gov.ua/en/works/lDBGYqZ7/
    Epidemiology of hyperhidrosis in 2 population-based health care databases […] Data on the population-based epidemiology of hyperhidrosis (HH) are scarce. This study investigated the epidemiology and healthcare of HH in Germany. In 2020, 0.70% of insured adults were confirmed to have HH (mean age 59.5 years, SD 18.9, 61.6% female), with 9.24% having a ‘localised’ form, 8.65% a ‘generalised’ form and 84.80% an ‘unspecified’ form. 0.04% of the total population had a severe form. The incidence was 0.35%. Localised HH was more common in younger age groups (18 to <30 years), while older age groups (70 to <80 years) were significantly more likely to suffer from generalised HH. General practitioners were most frequently involved in care. Inpatient stays due to HH were very rare, with 0.14% in 2019 and 0.04% in 2020. [...] Multisource data analysis connecting primary and secondary data will be needed for a complete picture of the healthcare and epidemiology of HH.
  • #4 Azthena logo with the word Azthena
    https://www.news-medical.net/health/Hyperhidrosis-Prognosis-and-Epidemiology.aspx
    It is difficult to say how many people develop hyperhidrosis as there are no guidelines to determine exactly what constitutes normal sweating, but estimates suggest that the worldwide prevalence is between 2% and 4%, without any particular gender predisposition. […] There are differences in prevalence globally, with one study, for example, having shown a prevalence of 2.9% in the US and up to 5.0% prevalence in certain areas of China.
  • #4 Hyperhidrosis prevalence and its impact on population – Hasimoto – Shanghai Chest
    https://shc.amegroups.org/article/view/5114/html
    Hyperhidrosis is a disorder characterized by excessive sweating which beyond the physiological need for body thermoregulation. The prevalence data available in the literature are practically nonexistent up to the beginning of the 21st century. The objective of this present study is to review the literature as a quest for studies that evaluated the prevalence of hyperhidrosis and its impact on the quality of life of individuals. The prevalence found in the articles varied from 0.072% to 16.3%. As to the impact on the quality of life, all articles have shown that such disorder affects in some way the life of the individuals. The data available in the literature regarding the prevalence of hyperhidrosis in the world population are practically nonexistent until the beginning of the 21st century, therefore up to some time ago little was known about the number of individuals bearing this disorder. The bibliographic review was done by using the PubMed database (until January 10th 2019). Sixteen articles (17-32) that evaluated the prevalence of hyperhidrosis were found in the research, 15 (18-32) of them were published from the 21st century. The prevalence of hyperhidrosis found in the articles ranged from 0.072% to 16.3%. The first citation found in the literature about the prevalence of hyperhidrosis is from 1977 (17). Adar et al. refers to a pilot epidemiological study, not published, carried out with young Israelis, where the reported incidence was from 0.6% to 1%. The first published work with methodological description was the one by Strutton et al. in 2004 (18). In this great American study, a formulated questionnaire was sent to 150,000 households aimed at identifying possible individuals who suffer from hyperhidrosis. The prevalence found was 2.9% (6,800 individuals) and the prevalence projected for the United States was 2.8% (7.8 million individuals). In 2007 China published two studies (19,20) about the prevalence of hyperhidrosis. The prevalence of palmar hyperhidrosis was 4.59%. The prevalence of palmar hyperhidrosis found in these three cities in the southeast of China was 4.36%. The two first Brazilian works were published in 2009 and in 2011, by Felini et al. (21) and Westphal et al. (22), respectively. The evaluation of such questionnaires revealed a 9% hyperhidrosis prevalence, the highest one published so far. The lowest prevalence of published hyperhidrosis was 0.072%, by Chu et al. (23). The information was collected in the National Health Insurance database of Taiwan. In 2013, Stefaniak et al. (24) conducted a work in Poland which included 253 students of medicine and dentistry. The prevalence found was 12.76% and the individuals did not have the diagnostic confirmed by a doctor. The highest prevalence published among all published papers was the one by Augustin et al. in 2013 (26). This study included 14,336 employees from 52 German companies. The prevalence found was 16.3% and all of the individuals were evaluated by a dermatologist. The third Brazilian work was published in 2015 by Lima et al. (27) and 447 students of the medicine course from two universities of the State of Sergipe were included. The prevalence found was 14.76%. A new study was published by the Chinese group in 2015 (28), this time involving 70,000 students. The prevalence found was 2.08% and the individuals had their diagnostic confirmed by a doctor. In 2016, with the objective of evaluating the prevalence of hyperhidrosis in different ethnic groups, a work was done by Liu et al. (29). The prevalence found was 14.6% in Shanghai and 12.3% in Vancouver. The last European published work was in 2016, by Shayesteh et al. (30). The prevalence of hyperhidrosis in this population was 5.5%. In 2016, Doolittle et al. (31) sent by e-mail an invitation to 275,904 people to participate in an online survey. The prevalence found was 4.8%. The most recent work about the prevalence of hyperhidrosis belongs to our group, published in 2018 (32). The work included 1,351 households, rounding up to 4,113 dwellers. At first 2.07% of the interviewees reported having hyperhidrosis, however, after the medical evaluation the prevalence dropped to 0.93%. The existing data of hyperhidrosis prevalence in the world population are well varied and questionable due to the heterogeneity of methodologies used in several studies. The scaling of the problem is important for the establishment of measures that take into consideration the identification, orientation and treatment, aimed at improving the quality of life of its patients.
  • #4 Hyperhidrosis: Management Options | AAFP
    https://www.aafp.org/pubs/afp/issues/2018/0601/p729.html
    Hyperhidrosis affects 1% to 3% of the U.S. population, yet less than one-half of those affected discuss this with their physician. More than 90% of hyperhidrosis cases are primary, and more than one-half of these cases affect the axillae. More than one-third of persons with axillary hyperhidrosis report that the condition is barely tolerable or completely intolerable, and it nearly always interferes with daily activities. Up to two-thirds of patients report a family history, suggesting a genetic predisposition. Although prevalence between sexes is roughly equal, women are more likely to report hyperhidrosis to their physician. […] Hyperhidrosis negatively impacts daily life, especially emotional well-being, self-esteem, interpersonal relationships, and occupational productivity. Although several tools have been developed to measure the impact of hyperhidrosis on quality of life, most are too complex to incorporate into office practice. The Hyperhidrosis Disease Severity Scale (HDSS) is a validated single-question survey with four grades of tolerability of sweating and impact on quality of life. This survey can estimate the effect on daily activities and response to treatment.
  • #4 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    Data published in 2016 found that: 1) the majority of palmar and plantar (66% and 61%, respectively) primary hyperhidrosis patients reported childhood onset (less than 12 years). 2) 36% of respondents reported that their primary axillary hyperhidrosis started before the age of 12 years. […] This 2016 study also showed that hyperhidrosis is often a lifelong struggle with symptom severity FAILING to lessen with age — 88% reported that symptoms have become worse or stayed the same over time. […] In a series of Taiwanese patients with palmar hyperhidrosis (1997), 75% had childhood onset, with the remainder presenting during puberty. […] In a study of 850 patients (2002) with palmar, axillary, or facial hyperhidrosis, 62% said they had the symptoms “as long as they could remember,” 33% said the onset occurred during puberty, and 5% reported their first symptoms as adults.
  • #4 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    A consumer survey of a nationally representative sample of 150,000 households in the U.S. screened for the presence of hyperhidrosis. Results showed that the prevalence of hyperhidrosis in the U.S. was 2.8% (7.8 million Americans). Of those with hyperhidrosis, only 38% consulted their physician about their excessive sweating. […] Recent research (from 2016 and 2018) expands upon the above older data regarding long delays among sufferers in discussing Hh with a healthcare professional (HCP) and in receiving care: 85% waiting 3+ years to discuss excessive sweating with an HCP and 50% waiting 10+ years to do so. […] 27% never receiving diagnosis. […] Among Hh sufferers who had not received any hyperhidrosis treatment, 38.5% said they were „not sure why not.” […] Recent data (2018) found that 18% of Hh sufferers report an immediate family member also suffering from excessive sweating.
  • #4 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    In the 2003 U.S. consumer survey (noted above), the average age at onset was 25 years, but varied with location of hyperhidrosis. […] Prevalence of the types of primary hyperhidrosis based on body location has been reported in numerous studies: […] In 2016, results from 1,985 survey participants showed that axillary hyperhidrosis was the most prevalent type of hyperhidrosis in the study sample (68%) followed by palmar (65%) and plantar (64%). […] More than 30% of survey respondents reported craniofacial, groin, or inframammary hyperhidrosis. […] It should be noted here, again, the primary focal Hh is most typically a multifocal disease. […] Key take-aways: primary Hh is relatively common, multifocal, and chronic with an onset in youth and an apparent genetic link — yet, diagnosis and treatment is often delayed for years.
  • #4
    https://pmc.ncbi.nlm.nih.gov/articles/PMC6326708/
    To determine the prevalence of primary hyperhidrosis in the city of Botucatu, Brazil, and to evaluate how this disorder affects the quality of life in those suffering from it. […] Excessive sweating was reported by 85 residents (prevalence = 2.07%), of whom 51 (60%) were female. […] the actual prevalence of primary hyperhidrosis in our sample was 0.93% and nearly 50% of the respondents with primary hyperhidrosis reported impaired quality of life. […] Data on the prevalence of hyperhidrosis are quite scarce in the medical literature. […] In our study, the prevalence of hyperhidrosis after the application of a questionnaire by trained interviewers was above 2%, as observed by Strutton et al. […] Therefore, after medical evaluation, the estimated prevalence of PH decreased to less than 1%. […] We conclude that the estimated prevalence of PH is near 1%, small in comparison with the number of subjects who report excessive sweating. The disorder affects the QoL in nearly 50% of subjects.
  • #4 Hyperhidrosis Disease Burden Requires Further Understanding
    https://www.dermatologytimes.com/view/hyperhidrosis-disease-burden-requires-further-understanding
    The cost of hospitalizations was found to be the highest in terms of economic burden of direct costs. […] Indirect costs are still not well understood, but despite this, 3 publications reported on productivity loss and the number of days prior to returning to work, which suggested that hyperhidrosis might have a negative social impact. […] This is the first comprehensive TLR study on hyperhidrosis including the epidemiology and disease burden of hyperhidrosis throughout regions to date, the authors noted. […] Future actions should include implementation of educational programs for physicians, medical specialists, and patients to raise awareness of the condition; the conduct of further studies with larger scope and bigger patient populations; and the generation of more evidence for Japan, concluded the authors.
  • #4 Epidemiology and health care of hyperhidrosis in Germany: claims data analysis | BMJ Open
    https://bmjopen.bmj.com/content/14/8/e085862
    Data on the population-based epidemiology of hyperhidrosis (HH) are scarce. This study investigated the epidemiology and healthcare of HH in Germany. In 2020, 0.70% of insured adults were confirmed to have HH (mean age 59.5 years, SD 18.9, 61.6% female), with 9.24% having a localised form, 8.65% a generalised form and 84.80% an unspecified form. The incidence was 0.35%. Localised HH was more common in younger age groups (18 to 30 years), while older age groups (70 to 80 years) were significantly more likely to suffer from generalised HH. In 2020, 0.70% (CI 0.70 to 0.70; table 1) of insured adults were diagnosed with HH. Extrapolated to the German population, these rates correspond to 500 000 persons with HH in medical care. In 2020, 0.35% (CI 0.35 to 0.35) of insured adults developed new cases of HH. On a federal state level, the highest prevalence of HH (standardised by age, gender and federal state) was observed in Saxony-Anhalt (0.94%), Mecklenburg-Western Pomerania (0.87%) and Brandenburg (0.82%). In 2020 4.88% were identified as having a severe form of the condition. The current prevalence of 0.7% is lower than the international published literature with 1%9.7%. The present analyses show that the majority of patients are treated by general practitioners and internists. Additional primary studies are needed to specify the epidemiology of the disease related to the care situation of patients with HH in Germany. […] The analysis of HH in claims data is limited since a relevant proportion of persons who do not seek medical care is not coded according to ICD-10 by the physician or pay for the treatment themselves.
  • #4 Population-based Cross-sectional Analysis of the Epidemiology of the Surgical Correction of Hyperhidrosis in 1216 Patients over 11 years | medRxiv
    https://www.medrxiv.org/content/10.1101/2021.09.14.21263594v1
    Background Endoscopic thoracic sympathectomy is the definitive surgical treatment for hyperhidrosis, and a nationwide study suggested that it has been performed in a higher rate than which could have been expected due to climate characteristics, comparing to the national statistics. […] Objectives To study the epidemiology of sympathectomy to treat hyperhidrosis in So Paulo, the largest city in the Southeast. […] Results 65.29% of the patients were female, 66.2% aged between 20 and 39 years and 37.59% had addresses registered outside So Paulo. 1216 procedures were performed in the city of So Paulo from 2008 to 2018, 78.45% of which in only two public hospitals. […] Conclusions sympathectomies for the treatment of HH were widely performed in the city of So Paulo (1216 procedures), mainly in young (20 -39 years) and female patients, with more than one third of the patients having addresses registered outside the city.
  • #4 Epidemiology of hyperhidrosis in 2 population-based health care databases – EM consulte
    https://www.em-consulte.com/es/article/1193840/epidemiology-of-hyperhidrosis-in-2-population-base
    Because the case ascertainment methods rely on available data for those seeking health care, we may have underestimated the number of HH cases in both countries. […] The findings represent a plausible estimate for incidence and prevalence of HH among persons seeking medical care for excessive sweating. Improved practices for identifying HH in clinical settings may increase the sensitivity and specificity of future studies and improve characterization and quantification of the population burden of this significant disease.
  • #5 Azthena logo with the word Azthena
    https://www.news-medical.net/health/Hyperhidrosis-Prognosis-and-Epidemiology.aspx
    It is difficult to say how many people develop hyperhidrosis as there are no guidelines to determine exactly what constitutes normal sweating, but estimates suggest that the worldwide prevalence is between 2% and 4%, without any particular gender predisposition. […] There are differences in prevalence globally, with one study, for example, having shown a prevalence of 2.9% in the US and up to 5.0% prevalence in certain areas of China.
  • #5 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    In the past, there was little data on the prevalence of primary hyperhidrosis (Hh). Recently, however, more studies have been published in the medical literature – with illuminating statistics: […] Researchers reported the prevalence of hyperhidrosis in the United States as 4.8%, representing approximately 15.3 million people. That’s almost twice as many people as previously believed and this makes Hh more common than autism, melanoma, psoriasis, and peanut allergies. In the study, the prevalence rate was shown to be highest among 18–39 year olds (8.8%) and lowest among children/adolescents (2.1%). […] A study showed that, in Sweden, prevalence of primary hyperhidrosis was 5.5% with severe, primary hyperhidrosis affecting 1.4% of the population. Secondary hyperhidrosis was observed in 14.8% of the study participants.
  • #5 Epidemiology – Primary Care Notebook
    https://primarycarenotebook.com/pages/paediatrics/hyperhydrosis/epidemiology
    The prevalence of hyperhidrosis is reported to be around 1%. This figure is thought to be much higher since the majority of cases are not reported to primary care. […] According to a large American national survey, only 38% of patients with a primary pattern of symptoms had consulted a health professional. […] It is estimated that there is a 15 year delay in presentation of patients with hyperhidrosis to primary care. […] In 30% to 50% of cases of primary hyperhidrosis, a family history is reported.
  • #5 Hyperhidrosis: Background, Pathophysiology, Etiology
    https://emedicine.medscape.com/article/1073359-overview
    In the United States and the United Kingdom, 1-1.6% of people have records reflecting hyperhidrosis. About 60% in both databases were women. […] In adolescents and young adults, an incidence rate of 0.6-1% is reported for hyperhidrosis. […] Palmoplantar hyperhidrosis occurs 20 times more frequently in the Japanese than in any other ethnic group. […] All races can be affected by hyperhidrosis; however, Japanese are reportedly affected more than 20 times more frequently than other ethnic groups. […] Both sexes can be affected by hyperhidrosis. […] Persons of all ages can be affected by hyperhidrosis. Localized hyperhidrosis, unlike generalized hyperhidrosis, usually begins in childhood or adolescence. In a study of 850 patients with palmar, axillary, or facial hyperhidrosis, 62% of patients reported that sweating began since before they could remember; 33%, since puberty; and 5%, during adulthood.
  • #5 Hyperhidrosis
    https://mobile.fpnotebook.com/Derm/Sweat/Hyprhdrs.htm
    Prevalence: 1-3% of U.S. […] Both genders affected equally (women report more often)
  • #5 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    A series of studies on patients treated by endoscopic thoracic sympathectomy (ETS) reported a family history in 35% and 56% of participants. […] A study of the familial aggregation of hyperhidrosis also suggested that the disorder may be more common than previously thought. […] When family history was analyzed in a group of patients with primary hyperhidrosis, 65% of patients reported a family history compared to no family history in controls. […] On the basis of these findings, the disease allele is present in 5% of the population, with an observed penetrance of 25%. […] The researchers (Ro and colleagues) concluded that because many of those with hyperhidrosis are reluctant to seek treatment, the previously reported incidence may be “a gross underestimation.” […] Focal primary hyperhidrosis usually has an onset during childhood or adolescence.
  • #5 Palmar Hyperhidrosis Epidemiology Forecast 2034
    https://www.expertmarketresearch.com/epidemiology-reports/palmar-hyperhidrosis-epidemiology-forecast
    A study published in the Journal of Marine Medical Society (2024) found that the most common site affected by excessive sweating in the Indian population was the palmoplantar region, which includes both the palms of the hands and the soles of the feet, with 43.8% of patients experiencing sweating in these areas. Palmar hyperhidrosis epidemiology forecast indicates that the second most commonly affected area was the palms, with 36.3% of patients reporting excessive sweating in this region. […] Expert Market Research’s Palmar Hyperhidrosis Epidemiology Forecast Report 2025-2034 offers comprehensive information on the prevalence and demographics of palmar hyperhidrosis. It projects the future incidence and prevalence rates of palmar hyperhidrosis across various populations. The study covers age and type as major determinants of the palmar hyperhidrosis-affected population. The report highlights patterns in the prevalence of palmar hyperhidrosis over time and projects future trends based on multiple variables.
  • #5 SciELO Brasil – Hyperhidrosis: prevalence and impact on quality of life Hyperhidrosis: prevalence and impact on quality of life
    https://www.scielo.br/j/jbpneu/a/gxS3VxQSW3j7hX5MkLXDxqz/
    Objective: To determine the prevalence of primary hyperhidrosis in the city of Botucatu, Brazil, and to evaluate how this disorder affects the quality of life in those suffering from it. […] A total of 4,133 residents, in 1,351 households, were surveyed. Excessive sweating was reported by 85 residents (prevalence = 2.07%), of whom 51 (60%) were female. […] Although the prevalence of self-reported excessive sweating was greater than 2%, the actual prevalence of primary hyperhidrosis in our sample was 0.93% and nearly 50% of the respondents with primary hyperhidrosis reported impaired quality of life. […] There are few data on the worldwide prevalence of hyperhidrosis, reported values ranging from 0.072% to 9%. […] In our study, the prevalence of hyperhidrosis after the application of a questionnaire by trained interviewers was above 2%, as observed by Strutton et al. However, after medical evaluation, 25% of the patients that reported excessive sweating actually showed normal sweating and 30% had SH. Consequently, more than half of the subjects that reported excessive sweating did not actually have PH. Therefore, after medical evaluation, the estimated prevalence of PH decreased to less than 1%.
  • #5 Population-based Cross-sectional Analysis of the Epidemiology of the Surgical Correction of Hyperhidrosis in 1216 Patients over 11 years | medRxiv
    https://www.medrxiv.org/content/10.1101/2021.09.14.21263594v1.full-text
    Background Endoscopic thoracic sympathectomy is the definitive surgical treatment for hyperhidrosis, and a nationwide study suggested that it has been performed in a higher rate than which could have been expected due to climate characteristics, comparing to the national statistics. […] Objectives To study the epidemiology of sympathectomy to treat hyperhidrosis in So Paulo, the largest city in the Southeast. […] Results 1216 procedures were performed in the city of So Paulo from 2008 to 2018, 78.45% of which in only two public hospitals. […] Conclusions sympathectomies for the treatment of HH were widely performed in the city of So Paulo (1216 procedures), mainly in young (20 -39 years) and female patients, with more than one third of the patients having addresses registered outside the city.
  • #5 Hyperhidrosis Limits Patients’ Daily Functioning, Quality of Life Across Several Different Regions
    https://www.hcplive.com/view/hyperhidrosis-limits-patients-daily-functioning-quality-of-life-across-several-different-regions
    The incidence of hyperhidrosis was found to have exhibited variations from 0.13% in the UK to 0.28% in the USA, with a higher occurrence being seen among females. […] Likewise, the investigators reported that hyperhidrosis’s prevalence ranged from 2.8% 4.8% for the US population to 18.40% for Chinese inpatients, whereas the axillary hyperhidrosis’s prevalence fluctuated from 1.4% for the US population to 5.75% for Japanese employees and/or students. […] While limited evidence exists on the hyperhidrosis burden, particularly among those in Japan, it still was shown to be a substantial hindrance to patients’ overall daily functioning. […] Despite limited data, available evidence suggests that hyperhidrosis places physical, psychological, and economic burdens on the daily lives of individual patients, they wrote. The introduction of new treatments is expected to improve the medical environment of hyperhidrosis and reduce the burden on patients. […] Understanding both the nature and impact of hyperhidrosis is of highest importance in addressing its challenges.
  • #6 Hyperhidrosis prevalence and its impact on population – Hasimoto – Shanghai Chest
    https://shc.amegroups.org/article/view/5114/html
    Hyperhidrosis is a disorder characterized by excessive sweating which beyond the physiological need for body thermoregulation. The prevalence data available in the literature are practically nonexistent up to the beginning of the 21st century. The objective of this present study is to review the literature as a quest for studies that evaluated the prevalence of hyperhidrosis and its impact on the quality of life of individuals. The prevalence found in the articles varied from 0.072% to 16.3%. As to the impact on the quality of life, all articles have shown that such disorder affects in some way the life of the individuals. The data available in the literature regarding the prevalence of hyperhidrosis in the world population are practically nonexistent until the beginning of the 21st century, therefore up to some time ago little was known about the number of individuals bearing this disorder. The bibliographic review was done by using the PubMed database (until January 10th 2019). Sixteen articles (17-32) that evaluated the prevalence of hyperhidrosis were found in the research, 15 (18-32) of them were published from the 21st century. The prevalence of hyperhidrosis found in the articles ranged from 0.072% to 16.3%. The first citation found in the literature about the prevalence of hyperhidrosis is from 1977 (17). Adar et al. refers to a pilot epidemiological study, not published, carried out with young Israelis, where the reported incidence was from 0.6% to 1%. The first published work with methodological description was the one by Strutton et al. in 2004 (18). In this great American study, a formulated questionnaire was sent to 150,000 households aimed at identifying possible individuals who suffer from hyperhidrosis. The prevalence found was 2.9% (6,800 individuals) and the prevalence projected for the United States was 2.8% (7.8 million individuals). In 2007 China published two studies (19,20) about the prevalence of hyperhidrosis. The prevalence of palmar hyperhidrosis was 4.59%. The prevalence of palmar hyperhidrosis found in these three cities in the southeast of China was 4.36%. The two first Brazilian works were published in 2009 and in 2011, by Felini et al. (21) and Westphal et al. (22), respectively. The evaluation of such questionnaires revealed a 9% hyperhidrosis prevalence, the highest one published so far. The lowest prevalence of published hyperhidrosis was 0.072%, by Chu et al. (23). The information was collected in the National Health Insurance database of Taiwan. In 2013, Stefaniak et al. (24) conducted a work in Poland which included 253 students of medicine and dentistry. The prevalence found was 12.76% and the individuals did not have the diagnostic confirmed by a doctor. The highest prevalence published among all published papers was the one by Augustin et al. in 2013 (26). This study included 14,336 employees from 52 German companies. The prevalence found was 16.3% and all of the individuals were evaluated by a dermatologist. The third Brazilian work was published in 2015 by Lima et al. (27) and 447 students of the medicine course from two universities of the State of Sergipe were included. The prevalence found was 14.76%. A new study was published by the Chinese group in 2015 (28), this time involving 70,000 students. The prevalence found was 2.08% and the individuals had their diagnostic confirmed by a doctor. In 2016, with the objective of evaluating the prevalence of hyperhidrosis in different ethnic groups, a work was done by Liu et al. (29). The prevalence found was 14.6% in Shanghai and 12.3% in Vancouver. The last European published work was in 2016, by Shayesteh et al. (30). The prevalence of hyperhidrosis in this population was 5.5%. In 2016, Doolittle et al. (31) sent by e-mail an invitation to 275,904 people to participate in an online survey. The prevalence found was 4.8%. The most recent work about the prevalence of hyperhidrosis belongs to our group, published in 2018 (32). The work included 1,351 households, rounding up to 4,113 dwellers. At first 2.07% of the interviewees reported having hyperhidrosis, however, after the medical evaluation the prevalence dropped to 0.93%. The existing data of hyperhidrosis prevalence in the world population are well varied and questionable due to the heterogeneity of methodologies used in several studies. The scaling of the problem is important for the establishment of measures that take into consideration the identification, orientation and treatment, aimed at improving the quality of life of its patients.
  • #6 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    Data published in 2016 found that: 1) the majority of palmar and plantar (66% and 61%, respectively) primary hyperhidrosis patients reported childhood onset (less than 12 years). 2) 36% of respondents reported that their primary axillary hyperhidrosis started before the age of 12 years. […] This 2016 study also showed that hyperhidrosis is often a lifelong struggle with symptom severity FAILING to lessen with age — 88% reported that symptoms have become worse or stayed the same over time. […] In a series of Taiwanese patients with palmar hyperhidrosis (1997), 75% had childhood onset, with the remainder presenting during puberty. […] In a study of 850 patients (2002) with palmar, axillary, or facial hyperhidrosis, 62% said they had the symptoms “as long as they could remember,” 33% said the onset occurred during puberty, and 5% reported their first symptoms as adults.
  • #6 Hyperhidrosis: Background, Pathophysiology, Etiology
    https://emedicine.medscape.com/article/1073359-overview
    In the United States and the United Kingdom, 1-1.6% of people have records reflecting hyperhidrosis. About 60% in both databases were women. […] In adolescents and young adults, an incidence rate of 0.6-1% is reported for hyperhidrosis. […] Palmoplantar hyperhidrosis occurs 20 times more frequently in the Japanese than in any other ethnic group. […] All races can be affected by hyperhidrosis; however, Japanese are reportedly affected more than 20 times more frequently than other ethnic groups. […] Both sexes can be affected by hyperhidrosis. […] Persons of all ages can be affected by hyperhidrosis. Localized hyperhidrosis, unlike generalized hyperhidrosis, usually begins in childhood or adolescence. In a study of 850 patients with palmar, axillary, or facial hyperhidrosis, 62% of patients reported that sweating began since before they could remember; 33%, since puberty; and 5%, during adulthood.
  • #6 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    A series of studies on patients treated by endoscopic thoracic sympathectomy (ETS) reported a family history in 35% and 56% of participants. […] A study of the familial aggregation of hyperhidrosis also suggested that the disorder may be more common than previously thought. […] When family history was analyzed in a group of patients with primary hyperhidrosis, 65% of patients reported a family history compared to no family history in controls. […] On the basis of these findings, the disease allele is present in 5% of the population, with an observed penetrance of 25%. […] The researchers (Ro and colleagues) concluded that because many of those with hyperhidrosis are reluctant to seek treatment, the previously reported incidence may be “a gross underestimation.” […] Focal primary hyperhidrosis usually has an onset during childhood or adolescence.
  • #6 SciELO Brazil – Epidemiologic analysis of prevalence of the hyperhidrosis* Epidemiologic analysis of prevalence of the hyperhidrosis*
    https://www.scielo.br/j/abd/a/cp4L8XGgLxpm6hPG6tZq99j/?lang=en
    HH manifests itself more frequently in more than one site, and the main complaint that most affects the patients is the palmar, which appears already in the adolescence. […] When there are two sweating sites, the most frequent combination is palmar + plantar, and when there are three sites of sweating, the most frequent combinations are: palmar + plantar + axillary and axillary + palmar + plantar.
  • #6 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    A consumer survey of a nationally representative sample of 150,000 households in the U.S. screened for the presence of hyperhidrosis. Results showed that the prevalence of hyperhidrosis in the U.S. was 2.8% (7.8 million Americans). Of those with hyperhidrosis, only 38% consulted their physician about their excessive sweating. […] Recent research (from 2016 and 2018) expands upon the above older data regarding long delays among sufferers in discussing Hh with a healthcare professional (HCP) and in receiving care: 85% waiting 3+ years to discuss excessive sweating with an HCP and 50% waiting 10+ years to do so. […] 27% never receiving diagnosis. […] Among Hh sufferers who had not received any hyperhidrosis treatment, 38.5% said they were „not sure why not.” […] Recent data (2018) found that 18% of Hh sufferers report an immediate family member also suffering from excessive sweating.
  • #6 Hyperhidrosis Limits Patients’ Daily Functioning, Quality of Life Across Several Different Regions
    https://www.consultantlive.com/view/hyperhidrosis-limits-patients-daily-functioning-quality-of-life-across-several-different-regions
    The incidence of hyperhidrosis was found to have exhibited variations from 0.13% in the UK to 0.28% in the USA, with a higher occurrence being seen among females. […] Likewise, the investigators reported that hyperhidrosis prevalence ranged from 2.8% 4.8% for the US population to 18.40% for Chinese inpatients, whereas the axillary hyperhidrosis prevalence fluctuated from 1.4% for the US population to 5.75% for Japanese employees and/or students. […] While limited evidence exists on the hyperhidrosis burden, particularly among those in Japan, it still was shown to be a substantial hindrance to patients’ overall daily functioning. […] Despite limited data, available evidence suggests that hyperhidrosis places physical, psychological, and economic burdens on the daily lives of individual patients, they wrote. The introduction of new treatments is expected to improve the medical environment of hyperhidrosis and reduce the burden on patients. […] Understanding both the nature and impact of hyperhidrosis is of highest importance in addressing its challenges.
  • #7 Epidemiology and health care of hyperhidrosis in Germany: claims data analysis | BMJ Open
    https://bmjopen.bmj.com/content/14/8/e085862
    Data on the population-based epidemiology of hyperhidrosis (HH) are scarce. This study investigated the epidemiology and healthcare of HH in Germany. In 2020, 0.70% of insured adults were confirmed to have HH (mean age 59.5 years, SD 18.9, 61.6% female), with 9.24% having a localised form, 8.65% a generalised form and 84.80% an unspecified form. The incidence was 0.35%. Localised HH was more common in younger age groups (18 to 30 years), while older age groups (70 to 80 years) were significantly more likely to suffer from generalised HH. In 2020, 0.70% (CI 0.70 to 0.70; table 1) of insured adults were diagnosed with HH. Extrapolated to the German population, these rates correspond to 500 000 persons with HH in medical care. In 2020, 0.35% (CI 0.35 to 0.35) of insured adults developed new cases of HH. On a federal state level, the highest prevalence of HH (standardised by age, gender and federal state) was observed in Saxony-Anhalt (0.94%), Mecklenburg-Western Pomerania (0.87%) and Brandenburg (0.82%). In 2020 4.88% were identified as having a severe form of the condition. The current prevalence of 0.7% is lower than the international published literature with 1%9.7%. The present analyses show that the majority of patients are treated by general practitioners and internists. Additional primary studies are needed to specify the epidemiology of the disease related to the care situation of patients with HH in Germany. […] The analysis of HH in claims data is limited since a relevant proportion of persons who do not seek medical care is not coded according to ICD-10 by the physician or pay for the treatment themselves.
  • #7 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    In the past, there was little data on the prevalence of primary hyperhidrosis (Hh). Recently, however, more studies have been published in the medical literature – with illuminating statistics: […] Researchers reported the prevalence of hyperhidrosis in the United States as 4.8%, representing approximately 15.3 million people. That’s almost twice as many people as previously believed and this makes Hh more common than autism, melanoma, psoriasis, and peanut allergies. In the study, the prevalence rate was shown to be highest among 18–39 year olds (8.8%) and lowest among children/adolescents (2.1%). […] A study showed that, in Sweden, prevalence of primary hyperhidrosis was 5.5% with severe, primary hyperhidrosis affecting 1.4% of the population. Secondary hyperhidrosis was observed in 14.8% of the study participants.
  • #7 Epidemiology of hyperhidrosis in 2 population-based health care databases. | Read by QxMD
    https://read.qxmd.com/read/28993234/epidemiology-of-hyperhidrosis-in-2-population-based-health-care-databases
    Epidemiology of hyperhidrosis in 2 population-based health care databases. […] Population-based and clinical case reports of hyperhidrosis (HH) provide prevalence estimates that vary widely across reported studies because of differences in case ascertainment. […] In this study, we specify diagnostic, symptom, and prescription codes for HH to estimate incidence and prevalence for the United Kingdom and the United States. […] Data from UK and US health care databases were analyzed to ascertain HH cases and estimate incidence and prevalence from health care records during calendar years 2011 through 2013. […] On the basis of 2013 data for the United States and United Kingdom, between 1.0% and 1.6% of these populations have health care records indicating diagnosis or treatment of HH. […] Women accounted for approximately 60% of incident and prevalent cases in both databases.
  • #7 Hyperhidrosis – Wikipedia
    https://en.wikipedia.org/wiki/Hyperhidrosis
    It is estimated that the incidence of focal hyperhidrosis may be as high as 2.8% of the population of the United States. […] It affects men and women equally, and most commonly occurs among people aged 25-64 years, though some may have been affected since early childhood. […] About 30-50% of people have another family member affected, implying a genetic predisposition. […] In 2006, researchers at Saga University in Japan reported that primary palmar hyperhidrosis maps to gene locus 14q11.2-q13.
  • #7 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    A consumer survey of a nationally representative sample of 150,000 households in the U.S. screened for the presence of hyperhidrosis. Results showed that the prevalence of hyperhidrosis in the U.S. was 2.8% (7.8 million Americans). Of those with hyperhidrosis, only 38% consulted their physician about their excessive sweating. […] Recent research (from 2016 and 2018) expands upon the above older data regarding long delays among sufferers in discussing Hh with a healthcare professional (HCP) and in receiving care: 85% waiting 3+ years to discuss excessive sweating with an HCP and 50% waiting 10+ years to do so. […] 27% never receiving diagnosis. […] Among Hh sufferers who had not received any hyperhidrosis treatment, 38.5% said they were „not sure why not.” […] Recent data (2018) found that 18% of Hh sufferers report an immediate family member also suffering from excessive sweating.
  • #8 Azthena logo with the word Azthena
    https://www.news-medical.net/health/Hyperhidrosis-Prognosis-and-Epidemiology.aspx
    It is difficult to say how many people develop hyperhidrosis as there are no guidelines to determine exactly what constitutes normal sweating, but estimates suggest that the worldwide prevalence is between 2% and 4%, without any particular gender predisposition. […] There are differences in prevalence globally, with one study, for example, having shown a prevalence of 2.9% in the US and up to 5.0% prevalence in certain areas of China.
  • #8 Hyperhidrosis Market Size, Share | Industry Forecast, 2034
    https://www.imarcgroup.com/hyperhidrosis-market
    The hyperhidrosis market has been comprehensively analyzed in IMARC’s new report titled „Hyperhidrosis Market: Epidemiology, Industry Trends, Share, Size, Growth, Opportunity, and Forecast 2024-2034”. […] Hyperhidrosis affects at least 176 million people globally. […] The prevalence of hyperhidrosis is approximately 15.3 million people in the US population. […] The prevalence rate is 2.1% among children and adolescents and people 65 years of age and beyond, with the largest rates occurring in the 18-39 age group (8.8%). […] In India, hyperhidrosis affects about 2.5-3 percent of the population. […] IMARC Group’s new report provides an exhaustive analysis of the hyperhidrosis market in the United States, EU4 (Germany, Spain, Italy, and France), United Kingdom, and Japan. This includes treatment practices, in-market, and pipeline drugs, share of individual therapies, market performance across the seven major markets, market performance of key companies and their drugs, etc. […] According to the report, the United States has the largest patient pool for hyperhidrosis and also represents the largest market for its treatment. […] The report also provides the current and future patient pool across the seven major markets.
  • #8 Epidemiology and health care of hyperhidrosis in Germany: claims data analysis | BMJ Open
    https://bmjopen.bmj.com/content/14/8/e085862
    Data on the population-based epidemiology of hyperhidrosis (HH) are scarce. This study investigated the epidemiology and healthcare of HH in Germany. In 2020, 0.70% of insured adults were confirmed to have HH (mean age 59.5 years, SD 18.9, 61.6% female), with 9.24% having a localised form, 8.65% a generalised form and 84.80% an unspecified form. The incidence was 0.35%. Localised HH was more common in younger age groups (18 to 30 years), while older age groups (70 to 80 years) were significantly more likely to suffer from generalised HH. In 2020, 0.70% (CI 0.70 to 0.70; table 1) of insured adults were diagnosed with HH. Extrapolated to the German population, these rates correspond to 500 000 persons with HH in medical care. In 2020, 0.35% (CI 0.35 to 0.35) of insured adults developed new cases of HH. On a federal state level, the highest prevalence of HH (standardised by age, gender and federal state) was observed in Saxony-Anhalt (0.94%), Mecklenburg-Western Pomerania (0.87%) and Brandenburg (0.82%). In 2020 4.88% were identified as having a severe form of the condition. The current prevalence of 0.7% is lower than the international published literature with 1%9.7%. The present analyses show that the majority of patients are treated by general practitioners and internists. Additional primary studies are needed to specify the epidemiology of the disease related to the care situation of patients with HH in Germany. […] The analysis of HH in claims data is limited since a relevant proportion of persons who do not seek medical care is not coded according to ICD-10 by the physician or pay for the treatment themselves.
  • #8 Epidemiology – Primary Care Notebook
    https://primarycarenotebook.com/pages/paediatrics/hyperhydrosis/epidemiology
    The prevalence of hyperhidrosis is reported to be around 1%. This figure is thought to be much higher since the majority of cases are not reported to primary care. […] According to a large American national survey, only 38% of patients with a primary pattern of symptoms had consulted a health professional. […] It is estimated that there is a 15 year delay in presentation of patients with hyperhidrosis to primary care. […] In 30% to 50% of cases of primary hyperhidrosis, a family history is reported.
  • #9 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    Research results found that the prevalence of primary hyperhidrosis among dermatology outpatients in Shanghai was 14.5% and in Vancouver was 12.3%. […] Data showed that multifocal hyperhidrosis is common with 81% of patients reporting three or more hyperhidrotic sites. […] Data presented as an abstract on „pediatric breaking news” showed that 17.1% of teens surveyed experience excessive, uncontrollable sweating based on published diagnostic criteria. […] Hyperhidrosis (extreme, uncontrollable sweating affecting 4.8% of people) is often misunderstood, misrepresented and mismanaged, but for the past 15 years the International Hyperhidrosis Society has been bringing the full range of stakeholders to the table to transform missed opportunities into an impactful mission. […] The above statistics are key updates on older research, which has been frequently cited:
  • #9 Hyperhidrosis and Its Impact on Those Living With It
    https://www.ajmc.com/view/hyperhidrosis-and-its-impact–on-those-living-with-it
    Hyperhidrosis affects approximately 4.8% of Americans. […] Primary hyperhidrosis reportedly affects 4.8% of Americans, or approximately 15.3 million individuals. […] Because it is often underreported and underdiagnosed, the true prevalence rates may be higher. […] It primarily affects younger adults aged 18 to 39 years. […] Rates are lowest among those 65 years and older, young children, and adolescents. […] It is speculated that lower prevalence among the elderly population is due to disease regression over time. […] Incidence rates do not appear to differ between genders. […] However, men may be more likely to be affected in craniofacial areas, although women are more likely to be affected in axillae areas. […] Some literature suggests a possible racial difference in the prevalence of primary hyperhidrosis, with more Japanese American patients affected by hyperhidrosis in the palms and soles.
  • #9 SciELO Brasil – Hyperhidrosis: prevalence and impact on quality of life Hyperhidrosis: prevalence and impact on quality of life
    https://www.scielo.br/j/jbpneu/a/gxS3VxQSW3j7hX5MkLXDxqz/
    In our study, the prevalence of PH was slightly higher among women, and the proportion of women diagnosed with PH increased significantly after the medical evaluation, because most of the men were shown to sweat a normal amount. […] We conclude that the estimated prevalence of PH is near 1%, small in comparison with the number of subjects who report excessive sweating. The disorder affects the QoL in nearly 50% of subjects.
  • #10 Hyperhidrosis: Background, Pathophysiology, Etiology
    https://emedicine.medscape.com/article/1073359-overview
    In the United States and the United Kingdom, 1-1.6% of people have records reflecting hyperhidrosis. About 60% in both databases were women. […] In adolescents and young adults, an incidence rate of 0.6-1% is reported for hyperhidrosis. […] Palmoplantar hyperhidrosis occurs 20 times more frequently in the Japanese than in any other ethnic group. […] All races can be affected by hyperhidrosis; however, Japanese are reportedly affected more than 20 times more frequently than other ethnic groups. […] Both sexes can be affected by hyperhidrosis. […] Persons of all ages can be affected by hyperhidrosis. Localized hyperhidrosis, unlike generalized hyperhidrosis, usually begins in childhood or adolescence. In a study of 850 patients with palmar, axillary, or facial hyperhidrosis, 62% of patients reported that sweating began since before they could remember; 33%, since puberty; and 5%, during adulthood.
  • #10 Epidemiology of Primary Hyperhidrosis – Focus on Hyperhidrosis
    https://www.medpagetoday.com/resource-centers/focus-hyperhidrosis/epidemiology-primary-hyperhidrosis/2281
    Data published in 2016 found that: 1) the majority of palmar and plantar (66% and 61%, respectively) primary hyperhidrosis patients reported childhood onset (less than 12 years). 2) 36% of respondents reported that their primary axillary hyperhidrosis started before the age of 12 years. […] This 2016 study also showed that hyperhidrosis is often a lifelong struggle with symptom severity FAILING to lessen with age — 88% reported that symptoms have become worse or stayed the same over time. […] In a series of Taiwanese patients with palmar hyperhidrosis (1997), 75% had childhood onset, with the remainder presenting during puberty. […] In a study of 850 patients (2002) with palmar, axillary, or facial hyperhidrosis, 62% said they had the symptoms “as long as they could remember,” 33% said the onset occurred during puberty, and 5% reported their first symptoms as adults.
  • #10 Hyperhidrosis and Its Impact on Those Living With It
    https://www.ajmc.com/view/hyperhidrosis-and-its-impact–on-those-living-with-it
    Hyperhidrosis affects approximately 4.8% of Americans. […] Primary hyperhidrosis reportedly affects 4.8% of Americans, or approximately 15.3 million individuals. […] Because it is often underreported and underdiagnosed, the true prevalence rates may be higher. […] It primarily affects younger adults aged 18 to 39 years. […] Rates are lowest among those 65 years and older, young children, and adolescents. […] It is speculated that lower prevalence among the elderly population is due to disease regression over time. […] Incidence rates do not appear to differ between genders. […] However, men may be more likely to be affected in craniofacial areas, although women are more likely to be affected in axillae areas. […] Some literature suggests a possible racial difference in the prevalence of primary hyperhidrosis, with more Japanese American patients affected by hyperhidrosis in the palms and soles.
  • #11 Hyperhidrosis prevalence and its impact on population – Hasimoto – Shanghai Chest
    https://shc.amegroups.org/article/view/5114/html
    Hyperhidrosis is a disorder characterized by excessive sweating which beyond the physiological need for body thermoregulation. The prevalence data available in the literature are practically nonexistent up to the beginning of the 21st century. The objective of this present study is to review the literature as a quest for studies that evaluated the prevalence of hyperhidrosis and its impact on the quality of life of individuals. The prevalence found in the articles varied from 0.072% to 16.3%. As to the impact on the quality of life, all articles have shown that such disorder affects in some way the life of the individuals. The data available in the literature regarding the prevalence of hyperhidrosis in the world population are practically nonexistent until the beginning of the 21st century, therefore up to some time ago little was known about the number of individuals bearing this disorder. The bibliographic review was done by using the PubMed database (until January 10th 2019). Sixteen articles (17-32) that evaluated the prevalence of hyperhidrosis were found in the research, 15 (18-32) of them were published from the 21st century. The prevalence of hyperhidrosis found in the articles ranged from 0.072% to 16.3%. The first citation found in the literature about the prevalence of hyperhidrosis is from 1977 (17). Adar et al. refers to a pilot epidemiological study, not published, carried out with young Israelis, where the reported incidence was from 0.6% to 1%. The first published work with methodological description was the one by Strutton et al. in 2004 (18). In this great American study, a formulated questionnaire was sent to 150,000 households aimed at identifying possible individuals who suffer from hyperhidrosis. The prevalence found was 2.9% (6,800 individuals) and the prevalence projected for the United States was 2.8% (7.8 million individuals). In 2007 China published two studies (19,20) about the prevalence of hyperhidrosis. The prevalence of palmar hyperhidrosis was 4.59%. The prevalence of palmar hyperhidrosis found in these three cities in the southeast of China was 4.36%. The two first Brazilian works were published in 2009 and in 2011, by Felini et al. (21) and Westphal et al. (22), respectively. The evaluation of such questionnaires revealed a 9% hyperhidrosis prevalence, the highest one published so far. The lowest prevalence of published hyperhidrosis was 0.072%, by Chu et al. (23). The information was collected in the National Health Insurance database of Taiwan. In 2013, Stefaniak et al. (24) conducted a work in Poland which included 253 students of medicine and dentistry. The prevalence found was 12.76% and the individuals did not have the diagnostic confirmed by a doctor. The highest prevalence published among all published papers was the one by Augustin et al. in 2013 (26). This study included 14,336 employees from 52 German companies. The prevalence found was 16.3% and all of the individuals were evaluated by a dermatologist. The third Brazilian work was published in 2015 by Lima et al. (27) and 447 students of the medicine course from two universities of the State of Sergipe were included. The prevalence found was 14.76%. A new study was published by the Chinese group in 2015 (28), this time involving 70,000 students. The prevalence found was 2.08% and the individuals had their diagnostic confirmed by a doctor. In 2016, with the objective of evaluating the prevalence of hyperhidrosis in different ethnic groups, a work was done by Liu et al. (29). The prevalence found was 14.6% in Shanghai and 12.3% in Vancouver. The last European published work was in 2016, by Shayesteh et al. (30). The prevalence of hyperhidrosis in this population was 5.5%. In 2016, Doolittle et al. (31) sent by e-mail an invitation to 275,904 people to participate in an online survey. The prevalence found was 4.8%. The most recent work about the prevalence of hyperhidrosis belongs to our group, published in 2018 (32). The work included 1,351 households, rounding up to 4,113 dwellers. At first 2.07% of the interviewees reported having hyperhidrosis, however, after the medical evaluation the prevalence dropped to 0.93%. The existing data of hyperhidrosis prevalence in the world population are well varied and questionable due to the heterogeneity of methodologies used in several studies. The scaling of the problem is important for the establishment of measures that take into consideration the identification, orientation and treatment, aimed at improving the quality of life of its patients.
  • #12 SciELO Brasil – Hyperhidrosis: prevalence and impact on quality of life Hyperhidrosis: prevalence and impact on quality of life
    https://www.scielo.br/j/jbpneu/a/gxS3VxQSW3j7hX5MkLXDxqz/
    Objective: To determine the prevalence of primary hyperhidrosis in the city of Botucatu, Brazil, and to evaluate how this disorder affects the quality of life in those suffering from it. […] A total of 4,133 residents, in 1,351 households, were surveyed. Excessive sweating was reported by 85 residents (prevalence = 2.07%), of whom 51 (60%) were female. […] Although the prevalence of self-reported excessive sweating was greater than 2%, the actual prevalence of primary hyperhidrosis in our sample was 0.93% and nearly 50% of the respondents with primary hyperhidrosis reported impaired quality of life. […] There are few data on the worldwide prevalence of hyperhidrosis, reported values ranging from 0.072% to 9%. […] In our study, the prevalence of hyperhidrosis after the application of a questionnaire by trained interviewers was above 2%, as observed by Strutton et al. However, after medical evaluation, 25% of the patients that reported excessive sweating actually showed normal sweating and 30% had SH. Consequently, more than half of the subjects that reported excessive sweating did not actually have PH. Therefore, after medical evaluation, the estimated prevalence of PH decreased to less than 1%.
  • #13 SciELO Brasil – Hyperhidrosis: prevalence and impact on quality of life Hyperhidrosis: prevalence and impact on quality of life
    https://www.scielo.br/j/jbpneu/a/gxS3VxQSW3j7hX5MkLXDxqz/
    In our study, the prevalence of PH was slightly higher among women, and the proportion of women diagnosed with PH increased significantly after the medical evaluation, because most of the men were shown to sweat a normal amount. […] We conclude that the estimated prevalence of PH is near 1%, small in comparison with the number of subjects who report excessive sweating. The disorder affects the QoL in nearly 50% of subjects.

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