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• #1 Gastroparesis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/gastroparesis/symptoms-causes/syc-20355787

  Gastroparesis is a condition in which the muscles in the stomach don’t move food as they should for it to be digested. […] Often, the cause of gastroparesis is not known. Sometimes it’s linked to diabetes. And some people get gastroparesis after surgery or after a viral illness. […] It’s not always clear what leads to gastroparesis. But sometimes damage to a nerve that controls the stomach muscles can cause it. This nerve is called the vagus nerve. […] Conditions such as diabetes or surgery to the stomach or small intestine can damage the vagus nerve and its branches.

• #2 Gastroparesis: Symptoms, Causes, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/15522-gastroparesis

  Gastroparesis means paralysis of the stomach. Its a functional disorder affecting your stomach nerves and muscles. It makes your stomach muscle contractions weaker and slower than they need to be to digest your food and pass it on to your intestines. This leads to food sitting too long in your stomach. […] Gastroparesis, which means stomach paralysis, is a condition affecting the nerves and muscles in your stomach. It interferes with the muscle activity (peristalsis) that moves food through your stomach and into your small intestine. When your stomach muscles and nerves cant activate correctly, your stomach cant process food or empty itself like it should. This holds up your whole digestive process. […] Healthcare providers often classify gastroparesis into sub-types based on whats causing it. For example, gastroparesis that occurs as a side effect of diabetes may be called diabetes-related gastroparesis. Gastroparesis that occurs as a complication of surgery may be called post-surgical gastroparesis. Gastroparesis that occurs for no identifiable reason is labeled as idiopathic gastroparesis.

• #3 Symptoms & Causes of Gastroparesis – NIDDK

  https://www.niddk.nih.gov/health-information/digestive-diseases/gastroparesis/symptoms-causes

  In most cases, doctors arent able to find the underlying cause of gastroparesis, even with medical tests. Gastroparesis without a known cause is called idiopathic gastroparesis. […] Diabetes is the most common known underlying cause of gastroparesis. Diabetes can damage nerves, such as the vagus nerve and nerves and special cells, called pacemaker cells, in the wall of the stomach. The vagus nerve controls the muscles of the stomach and small intestine. If the vagus nerve is damaged or stops working, the muscles of the stomach and small intestine do not work normally. The movement of food through the digestive tract is then slowed or stopped. Similarly, if nerves or pacemaker cells in the wall of the stomach are damaged or do not work normally, the stomach does not empty. […] In addition to diabetes, other known causes of gastroparesis include injury to the vagus nerve due to surgery on your esophagus, stomach, or small intestine, hypothyroidism, certain autoimmune diseases, such as scleroderma, certain nervous system disorders, such as Parkinsons disease and multiple sclerosis, viral infections of your stomach.

• #4 Gastroparesis: Symptoms, Causes, & Advanced Treatment

  https://www.yashodahospitals.com/blog/gastroparesis-symptoms-causes-and-treatment/

  Gastroparesis is a disorder that causes mild or inefficient contractions of the stomach muscles, slowing food movement through the small intestine. […] While its exact cause remains unclear, it is sometimes linked to diabetes. In some cases, it can develop after surgery or a viral illness. […] The exact cause of the gastroparesis is not known. However, gastroparesis can be caused by damage to the vagus nerve, which controls stomach muscles and manages the digestive tract. A damaged vagus nerve may cause food to stay in the stomach longer. Some of the specific causes include: […] Diabetes: High blood sugar in diabetes usually causes nerve damage over time, disrupting the stomach contractions. […] Surgery on the stomach or its adjacent organs like the esophagus or intestines can, at times, destroy the nerves controlling stomach emptying.

• #5 Gastroparesis: Etiology, clinical manifestations, and diagnosis – UpToDate

  https://www.uptodate.com/contents/gastroparesis-etiology-clinical-manifestations-and-diagnosis

  Gastroparesis: Etiology, clinical manifestations, and diagnosis […] ETIOLOGY […] Although multiple conditions have been associated with gastroparesis, the majority of cases are idiopathic, diabetic, iatrogenic (eg, medication-induced), or postsurgical.

• #6 Gastroparesis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK551528/

  Gastroparesis is most frequently idiopathic. Other common etiologies include diabetic, postsurgical, and postinfectious causes. […] The most common etiology of gastroparesis is idiopathic, followed by diabetic, postsurgical, and postinfectious causes. […] Various neurologic disorders can also affect gastrointestinal motility by altering the parasympathetic or sympathetic nerve supply to the gastrointestinal (GI) tract. Etiologic categories of gastroparesis include but are not limited to: […] Patients with diabetes at increased risk of developing gastroparesis usually have a combination of the following: long duration of the disease, poorly controlled blood sugars, and other autonomic neuropathic complications. […] Gastroparesis is common following surgery involving the esophagus, stomach, duodenum, or pancreas and procedures that risk injury to the vagal nerve.

• #7 Causes of Gastroparesis – About Gastroparesis

  https://aboutgastroparesis.org/what-is-gastroparesis/causes-of-gastroparesis/

  There are a number of things that may contribute to or cause gastroparesis. In the majority of people with gastroparesis, the cause is unknown and is termed idiopathic. This is the most common subset of gastroparesis. The term idiopathic simply means that there is no known cause of the disease. An average of 30% to 50% of patients with gastroparesis have a diagnosis of idiopathic gastroparesis. […] Some people with idiopathic gastroparesis report symptoms following a virus infection (post-infectious or post-viral gastroparesis). […] Long-standing diabetes is the most common known cause of gastroparesis, although only a small percentage of people with diabetes develop gastroparesis. […] About 25% of gastroparesis patients are diagnosed with diabetic gastroparesis. […] In many people, viral infections are a cause. […] GP can occur when surgery changes the stomach. […] Less frequently, gastroparesis is seen to occur after the use of certain medications. […] Other causes of GP are neurologic. […] Much remains to be learned about what causes gastroparesis.

• #8 Gastroparesis for the nongastroenterologist | Cleveland Clinic Journal of Medicine

  https://www.ccjm.org/content/91/6/373

  Gastroparesis is a heterogeneous motility disorder characterized by nausea, vomiting, and postprandial fullness. […] Its epidemiology is unclear, and the main causes are diabetes mellitus and idiopathic disease. […] Although diabetes mellitus accounts for more than one-third of all cases of gastroparesis, other risk factors include gastrointestinal surgery, medications, and neurologic and autoimmune disorders. […] Diabetes and idiopathic disease are the most common causes of gastroparesis. However, the etiology differs among studies and populations. […] A large national claims database study from the United States reported diabetes mellitus as the most common cause, involving 57.4% of all cases, with type 2 diabetes being more prevalent than type 1. […] Interestingly, the etiology varies in other countries and regions.

• #9 Gastroparesis Diagnosis & Treatment | Nationwide Children’s

  https://www.nationwidechildrens.org/conditions/gastroparesis

  Gastroparesis can be caused by viral infections, scar tissue, previous stomach surgery, some medications, neurologic problems, and endocrine problems including diabetes, adrenal problems, and thyroid disease. […] However, in as many as 60% of children with gastroparesis, the cause is not known. […] If an underlying disease or problem is found that is causing the gastroparesis, this should be treated if at all possible.

• #10 Causes of Gastroparesis | Gastroparesis Symptoms | Gastroparesis Clinic

  https://www.gastroparesis.mindovergut.com/causes-of-gastroparesis/

  The term idiopathic means that the cause for a condition cannot be identified. This is very common in gastroparesis, with over 30% of cases being idiopathic. […] Post-infectious gastroparesis is also considered to be idiopathic. Post-infectious gastroparesis refers to the onset of gastroparesis symptoms after an infection (e.g. gastroenteritis, Epstein-Barr, Hawaii and Norwalk viruses, rotavirus). […] Diabetes is common among people with gastroparesis, with nearly 1 in 3 gastroparesis sufferers also having diabetes. […] In diabetes, high blood glucose levels can cause nerve damage that affects stomach function. This nerve damage can slow down gastric emptying and lead to gastroparesis symptoms. […] Around 13% of gastroparesis cases are post-surgical. Post-surgical gastroparesis occurs when the vagus nerve is damaged or intentionally cut during surgery.

• #11 Gastroparesis Causes, Symptoms, Diagnosis, and Treatment

  https://www.webmd.com/digestive-disorders/digestive-disorders-gastroparesis

  Gastroparesis is a condition in which food stays in your stomach for a longer period than it should. […] For most people, doctors can’t figure out what brings on gastroparesis. They do know that it often affects women more than men. […] Diabetes is the most common known cause of gastroparesis. It can damage nerves including the vagus nerve, which regulates your digestive system and certain cells in your stomach. […] Some things can make you more prone to getting gastroparesis, including: Injury to your vagus nerve from surgery, A lack of thyroid hormone (hypothyroidism), Viral stomach infections (gastroenteritis), Medications such as narcotics and some antidepressants, Parkinson’s disease, Multiple sclerosis, Rare conditions such as amyloidosis and scleroderma. […] Doctors don’t always know what causes gastroparesis, but diabetes is one common cause.

• #12 Gastroparesis Overview | Northwestern Medicine

  https://www.nm.org/conditions-and-care-areas/gastroenterology/gastroparesis

  Gastroparesis can have a number of causes, but it is most commonly associated with diabetes, particularly type 1 diabetes. […] Diabetics with gastroparesis can have a hard time managing their blood sugar, as there is a prolonged delay before sugars from food enter the bloodstream.

• #13 Gastroparesis – IFFGD

  https://iffgd.org/gi-disorders/upper-gi-disorders/gastroparesis/

  Gastroparesis (GP) is a condition of slowed stomach emptying with no intestinal blockage. […] There are three specific groups of GP causes but many rare causes also exist: […] Idiopathic GP This is the most common. Idiopathic simply means that there is no known cause of the disease. An average of 30% to 50% of patients with gastroparesis have a diagnosis of idiopathic gastroparesis. […] Diabetic GP- Diabetes mellitus is a disorder in which the body does not produce enough or respond normally to insulin. […] Diabetic GP occurs when slow emptying of the stomach occurs in people with diabetes. About 25% of GP patients are diagnosed with diabetic GP. […] Post-surgical GP can occur when surgery changes the stomach. This can be through damage to nerves or the formation of scar tissue damage to the stomach.

• #14 Gastroparesis > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/gastroparesis

  Gastroparesis is often caused by damage to nerves that stimulate the stomach muscles to contract. These large and small nerves play an important role in controlling the muscles in the stomach that are involved in moving food out of the stomach to the small intestine. […] While a number of medical conditions have been linked to gastroparesis, in nearly 4 out of 10 cases, doctors are unable to determine what caused the disorder. This is known as idiopathic gastroparesis. […] Causes of gastroparesis include: […] Diabetes. About 30% of gastroparesis cases are associated with diabetes. […] Viral infection. Certain viruses, including norovirus and rotavirus, have been linked to gastroparesis. […] Medications. Various medications, including calcium channel blockers, opiates, and progesterone, can slow the movement of food through the stomach.

• #15

  https://reverehealth.com/live-better/understanding-gastroparesis-causes-symptoms-and-treatments/

  Gastroparesis is an uncommon illness, occurring only in about 10 men and 40 women out of 100,000. […] Finding the underlying causes for gastroparesis is challenging even with extensive medical testing. Nearly 36 percent of cases are not linked to any known cause. Circumstances like this are known as idiopathic gastroparesis. […] The most common cause of gastroparesis is diabetes. Diabetes can damage the vagus nerve and the pacemaker cells in your stomach wall. Your vagus nerve controls the muscles of your stomach and small intestine. If damaged, your vagus nerve can prevent your stomach muscles and small intestines from working properly, potentially causing a damaged digestive tract. Additionally, if the pacemaker cells are damaged, your stomach will not empty properly. […] In addition to diabetes, there are other known causes of gastroparesis, including: Injury to the vagus nerve due to surgery of the esophagus, stomach, or small intestine, Hypothyroidism, Certain autoimmune diseases such as scleroderma, Some nervous system disorders such as multiple sclerosis and Parkinsons disease, Viral stomach infections, High blood sugar.

• #16 What Is Diabetic Gastroparesis? Symptoms, Diagnosis, and Treatment

  https://www.webmd.com/diabetes/diabetes-and-gastroparesis

  Diabetic gastroparesis results from a variety of factors, including high blood sugar levels and problems with the vagus nerve. The vagus nerve controls how quickly your stomach empties. When it’s damaged, digestion slows down, and food stays in your body longer than it should. […] Over time, diabetes can affect other parts of your body. It can cause problems with your stomachs smooth muscle and pacemaker cells, which help move food in and out of the stomach. […] Diabetes gastroparesis is a complication of having uncontrolled or poorly controlled type 1 or type 2 diabetes. It happens when high blood sugar levels start affecting your stomach muscles and cells, causing problems with how food leaves your stomach. […] Oxidative stress is when your body has too many free radicals (unstable molecules) and not enough antioxidants to remove them. It can also contribute to you having diabetic gastroparesis by causing your body to lose functions that help your stomach muscles contract and relax. […] Reducing your intake of fatty and high-fiber foods, eating easy-to-digest foods, and having smaller meals more often can help prevent gastroparesis symptoms.

• #17 Knowing The Causes And Symptoms Of Gastroparesis

  https://pegasushomecare.com/services/pegasus-personal-care/ways-personal-care-can-help/knowing-the-causes-and-symptoms-of-gastroparesis/

  diabetes approximately 33% of all people who have diabetes will also develop gastroparesis. This is because diabetes causes damage to those nerves in the stomach and it also might damage blood vessels which typically carry oxygen to the tissues, nerves, and muscles in the stomach area. […] autoimmune disease when your immune system sends antibodies to attack your own body cells, its because it mistakes them for an infection. Antibodies can cause damage to stomach nerves, and that can bring on a case of autoimmune gastroparesis. […] surgery anytime you have surgery performed on your stomach, theres a possibility that the vagus nerve will be damaged as a byproduct of surgery. This is a critical nerve that coordinates all stomach movements and runs the entire length of the stomach. If this gets damaged, you may have immediate gastroparesis or it can develop anytime after surgery, even years later.

• #18 Gastroparesis | Causes, Symptoms, Treatment & Diet | Guts UK Charity

  https://gutscharity.org.uk/advice-and-information/conditions/gastroparesis/

  Gastroparesis is a condition that affects the stomach. The name means stomach (gastro) paralysis (paresis). Gastroparesis is a chronic (long-term) disorder. In gastroparesis, the stomach does not empty its contents in the usual way. There is no obstruction or structural abnormality that causes the symptoms. Nerves that tell the stomach to empty are not effective, so the stomach is too slow in moving food through. […] In adults the most common cause of gastroparesis is diabetes. When diabetes is difficult to manage, it can cause high blood sugar levels. High blood sugar levels can damage the stomach nerves over time. Diabetic gastroparesis is the name for this type of gastroparesis. It affects 13 out of every 1,000 people with diabetes. Gastroparesis is more common in people with type 1 diabetes. But it can occur in people with type 2 diabetes as well.

• #19 Gastroparesis > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/gastroparesis

  Surgery. Surgical procedures may damage the vagus nerve, impairing the function of the muscles in the stomach. […] Autoimmune gastrointestinal dysmotility (AGID). AGID is an autoimmune condition in which the nerves that control muscles in the stomach are damaged, reducing their ability to propel food through the stomach. […] Neurological disorders. Parkinsons disease, multiple sclerosis, and other neurological disorders have been linked to gastroparesis. […] Other conditions, including amyloidosis and scleroderma, have also been linked to gastroparesis.

• #20 Gastroparesis | Causes, Symptoms, Treatment & Diet | Guts UK Charity

  https://gutscharity.org.uk/advice-and-information/conditions/gastroparesis/

  In many people, the cause of gastroparesis is unknown, which is called idiopathic gastroparesis. This is the next commonest type of gastroparesis after diabetic gastroparesis. […] Gastroparesis can also occur for a variety of other reasons. These include neurological conditions: Multiple sclerosis, Parkinson’s disease, connective tissue conditions, such as diffuse systemic sclerosis. It can also happen after surgery, for example: Oesophagus (gullet) surgery, acid reflux surgery (known as fundoplication), gastric bypass surgery, partial gastric resection (removal of part of the stomach), surgery to cut the vagus nerve – a treatment for stomach ulcers (vagotomy), lung surgery or pancreatic surgery. […] It is possible but not proven that gastroparesis may follow gastrointestinal infections.

• #21 Gastroparesis | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/gastroparesis

  Gastroparesis may appear after an infection. […] Unfortunately, experts don’t yet know exactly what causes gastroparesis. Sometimes, damage to the vagus nerve which helps manage the digestive tract can result in gastroparesis. If the vagus nerve is damaged, it cant send the signals to the stomach muscles to contract and push food into the small intestine, resulting in food staying in the stomach longer and pain to occur. […] Other risk factors include: Surgery particularly fundoplication, a procedure that controls reflux in patients with gastroesophageal reflux disease (GERD) […] Medications, such as anticholinergics and certain chemotherapy drugs […] Congenital defects that affect the stomach or abdomen, such as gastroschisis, which cause a baby’s intestines to stick out of the body […] Other underlying conditions, including type 1 and type 2 diabetes, hypothyroidism, neurologic disorders, or metabolic disorders such as Riley Day syndrome.

• #22 Gastroparesis: Symptoms, Causes, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/15522-gastroparesis

  Around one-third of people with diabetes (Type 1 or Type 2) develop gastroparesis. Diabetes-related gastroparesis is a type of diabetes-related neuropathy. It happens when high blood sugar levels damage your nerves. High blood sugar levels also damage the blood vessels that carry oxygen to your tissues, so your stomach nerves and muscles are both affected. […] Surgery on or near your stomach can injure the vagus nerve that runs through your stomach and coordinates its movements. Post-surgical gastroparesis can develop any time after surgery. Sometimes it happens right away, but it can also develop months (or even years) later. […] Gastrointestinal infections can trigger gastroparesis. Viral infections such as norovirus and rotavirus are more common causes, but bacterial infections can cause it too. Scientists arent sure whether its the infections themselves that damage your stomach nerves or if the immune cells meant to kill the infection damage your nerves by mistake.

• #23 Gastroparesis: Understanding Its Causes, Symptoms, and Diagnosis

  https://gatgi.com/blog/gastroparesis-understanding-its-causes-symptoms-and-diagnosis/

  Gastroparesis is a disorder that affects the normal movement of the stomach muscles. This means your stomach takes longer than usual to empty its contents into the small intestine. […] One primary cause of gastroparesis is damage to the vagus nerve, which controls stomach muscles. When this nerve is damaged, the muscles of the stomach and intestines do not work properly, slowing the movement of food through the digestive system. […] Several risk factors can increase the likelihood of developing gastroparesis. They include: People with diabetes, particularly type 1 diabetes, are at higher risk. Viral infections can lead to inflammation and damage to the nerves that control gastric motility. Individuals who have had abdominal or esophageal surgery may experience changes in their digestive system’s normal functioning, increasing their risk. Surgery complications can damage the nerves that control stomach function. Scar tissue from surgery can block or disrupt normal digestion. Certain autoimmune diseases contribute to the development of this condition. Medications such as narcotics and antidepressants can impact stomach movement. Eating disorders also play a role in increasing the risk.

• #24 Gastroparesis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK551528/

  Postinfectious is common and typically self-limited; full recovery is usual. Norwalk virus and rotavirus are the most commonly identified etiologic viral pathogens. However, Epstein-Barr virus, cytomegalovirus, and Varicella Zoster virus have also been implicated in gastroparesis due to their potential to cause long-term autonomic dysfunction.

• #25 Gastroparesis Symptoms, Treatment, Causes | UCLA Medical School

  https://medschool.ucla.edu/news-article/gastroparesis-symptoms-treatment-and-causes

  Gastroparesis is a medical condition that affects the stomach’s ability to properly empty its contents into the small intestine. This condition occurs when the muscles in the stomach which are responsible for pushing food through the digestive tract become impaired or weakened. As a result, food stays in the stomach for a longer time than normal, leading to various digestive symptoms. […] The exact cause of gastroparesis is not always clear, and it can result from a variety of factors. Some common causes and risk factors include: […] Diabetes: Gastroparesis is often linked to diabetes, especially when blood sugar levels are poorly controlled. Why? High blood glucose levels can damage the vagus nerve, which controls the muscles responsible for stomach emptying. […] Infections: Viral infections, such as herpes simplex or Epstein-Barr virus, can sometimes trigger the condition. Some instances have even been linked to the recent pandemic: Weve started seeing some cases of post-Covid gastroparesis, Dr. Gluckman reveals.

• #26 Understanding Gastroparesis: Causes, Symptoms, and Diagnosis- Dr. Vikrant Kale

  https://www.drkalegastroclinic.com/understanding-gastroparesis-causes-symptoms-and-diagnosis/

  Gastroparesis is a gastrointestinal disorder that affects the normal movement of the muscles in the stomach, leading to delayed emptying. […] Several factors can cause gastroparesis, including: […] Diabetes is the most common reason for gastroparesis. Over time, high blood sugar levels can harm the nerves that control the movement of the stomach. […] Gastroparesis can also be caused by damage to the vagus nerve, which is a nerve that controls the digestive system. This damage can be caused by disorders such as Parkinsons disease, multiple sclerosis, and stroke. […] Certain medications can slow the activity of the stomach, including opioids, anticholinergics, and tricyclic antidepressants. […] Infections, such as cytomegalovirus (CMV) infection, can also cause gastroparesis. […] Connective tissue disorders, such as scleroderma and lupus, can also cause gastroparesis. […] Certain abdominal surgeries can lead to damage or disorder of the vagus nerve.

• #27 Gastroparesis – familydoctor.org

  https://familydoctor.org/condition/gastroparesis/

  Gastroparesis is a disorder involving your stomach muscles. It is sometimes called delayed gastric emptying. Normally, after you swallow food, your stomach muscles begin squeezing and tightening. These movements are called contractions. This crushes the food and moves it into the small intestine to continue the digestive process. If you have gastroparesis, your stomach muscles don’t contract properly. This can delay or prevent the process of crushing the food and sending it to the small intestine. […] People who have diabetes are most at risk for gastroparesis. That’s because high blood sugar levels damage your nerves. In this case, it’s your vagus nerve. The vagus nerve tells your stomach muscles when to contract. Damage to this nerve is one of the most common causes of gastroparesis. Diabetes also can damage the blood vessels that carry oxygen and nutrients to the vagus nerve. Other things that cause gastroparesis include: Certain medicines. This includes certain pain medicines, antidepressants, and others. Surgery on the esophagus (the tube that runs from the mouth to the stomach), the stomach or the upper small intestine. Radiation of the chest or stomach for cancer treatment. Eating disorders, such as anorexia nervosa and bulimia. Gastroesophageal reflux disease (GERD). Other disorders, including hypothyroidism, scleroderma, Parkinson’s disease and some autoimmune disorders. Viral infections such as the flu (this is rare).

• #28 Gastroparesis: Symptoms, Causes, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/15522-gastroparesis

  In autoimmune disease, your immune system sends antibodies to attack your own body cells, mistaking them for an infection. New research indicates that these autoantibodies may damage the nerves in your stomach. […] Certain medications and recreational drugs can block the nerve signals that activate your stomach muscles. This can lead to temporary gastroparesis. […] Less common causes of gastroparesis include: […] Conditions affecting your nervous system may cause your stomach nerves to malfunction, such as Parkinsons disease, multiple sclerosis or autonomic dysfunction. […] Chronic inflammatory connective tissues diseases can degenerate your stomach muscles, including amyloidosis, scleroderma, lupus and Ehlers-Danos syndrome. […] Conditions affecting your endocrine system can cause chemical nerve damage, including thyroid disease, adrenal disorders, electrolyte imbalances and kidney failure. […] Cystic fibrosis causes mucus to build up in your gastrointestinal tract, slowing down motility throughout. An estimated one-third of people with CF have gastroparesis.

• #29 Gastroparesis (Causes, Symptoms, and Treatment) | Patient Leaflet

  https://patient.info/digestive-health/gastroparesis

  After some types of surgery – particularly weight loss surgery or surgery to the oesophagus, stomach or bowel – gastroparesis can occur. […] Drug-induced gastroparesis accounts for about 12 in 100 cases of gastroparesis. This can occur as a result of various medications including strong painkillers (opioids), calcium channel blockers, GLP-1 inhibitors or tricyclic antidepressants. […] Gastroparesis can occur temporarily following a viral or bacterial infection. […] Gastroparesis is a rare complication of some auto-immune conditions such as hypothyroidism or systemic sclerosis. […] Some neurological conditions such as multiple sclerosis, Parkinson’s disease, or following a stroke, increase the risk of gastroparesis although this is not common.

• #30 Gastroparesis | Causes, Symptoms, Treatment & Diet | Guts UK Charity

  https://gutscharity.org.uk/advice-and-information/conditions/gastroparesis/

  Medicines can cause gastroparesis, particularly opioid based medicines. […] Idiopathic gastroparesis is the most common cause of gastroparesis in children. In 7 out of 10 children, the diagnosis is idiopathic gastroparesis. Medication is the second most common cause. Medication-related gastroparesis affects 9 out of every 50 children with gastroparesis. A diagnosis of diabetic gastroparesis is given to 1 in every 25 children with diabetes. […] There is evidence that people who have eating disorders can experience delayed gastric emptying. If you suspect an eating disorder, please discuss this with your doctor.

• #31 Gastroparesis Causes | Stanford Health Care

  https://stanfordhealthcare.org/medical-conditions/digestion-and-metabolic-health/gastroparesis/causes.html

  Gastroparesis occurs when the nerves to the stomach are damaged or don’t work. Diabetes is the most common cause. Other causes include some disorders of the nervous system, such as Parkinson’s disease and stroke, and some medicines, such as tricyclic antidepressants, calcium channel blockers, and opioid pain relievers. This condition can also be a complication of gastric surgery.

• #32 Gastroparesis Symptoms, Treatment, Causes | UCLA Medical School

  https://medschool.ucla.edu/news-article/gastroparesis-symptoms-treatment-and-causes

  Surgery: Certain abdominal surgeries, such as those involving the stomach or esophagus, can increase the risk of developing gastroparesis by damaging the vagus nerve. […] Medications: Some medications, such as opioid pain medicines and anticholinergic drugs, can slow down stomach emptying. With these newer weight loss medicines like semaglutide many patients are developing gastroparesis as a side effect, Dr. Gluckman also notes. […] Neurological Disorders: Conditions like Parkinson’s disease and multiple sclerosis can affect the nerves that control stomach motility. […] Autoimmune Diseases: Certain autoimmune conditions can affect the nerves and muscles in the gastrointestinal tract. […] Idiopathic: In some cases, the exact cause of gastroparesis remains unknown, and it is referred to as idiopathic gastroparesis. And this is the largest group, according to Dr. Gluckman.

• #33 Gastroparesis – Wikipedia

  https://en.wikipedia.org/wiki/Gastroparesis

  Transient gastroparesis may arise in acute illness of any kind, as a consequence of certain cancer treatments or other drugs which affect digestive action, or due to abnormal eating patterns. […] Patients with cancer may develop gastroparesis because of chemotherapy-induced peripheral neuropathy, immunosuppression followed by viral infections involving the GI tract, procedures such as celiac blocks, paraneoplastic neuropathy or myopathy, or after an allogeneic bone marrow transplant via graft-versus-host disease. […] An analysis by University Hospitals Cleveland Medical Center of records from the TriNetX database found that the number of patients diagnosed with gastroparesis after being prescribed a GLP-1 receptor agonist (0.1% of the patients) was 250% greater than the number of patients diagnosed with gastroparesis who did not take a GLP-1 medication (0.04%).

• #34 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Gastroparesis-Causes.aspx

  Gastroparesis is a long term condition. It leads to inability of the stomach to empty its contents in the intestines. There is usually no blockage but damage to the vagus nerve. The most common cause of gastroparesis however is underlying diabetes mellitus. Diabetes leads to increased blood sugar. Raise blood sugar often damages blood vessels that supply essential nutrients to the nerves. Over time diabetes damages nerves in a process called neuropathy. When the vagus nerve is damaged it predisposes a person to develop gastroparesis. […] Other causes of gastroparesis include:- Gastroparesis may occur after surgical damage to the stomach muscles and nerves. This may occur as a complication of some types of surgery, such as removal of part of the stomach or gastrectomy. Some medicines also cause gastroparesis. Medications and drugs associated with impaired gastric emptying include narcotics, tricyclic antidepressants, calcium channel blockers (like verapamil), clonidine, dopamine agonists (such as those used in Parkinsons disease), Lithium (used for bipolar disorders), Nicotine and Progesterone. Nerve diseases like Parkinsons disease also lead to gastroparesis. Multiple sclerosis is another important cause of gastroparesis. Diseases like amyloidosis and sclerosderma may also cause gastroparesis. Scleroderma results in hard, thickened areas of skin and other areas. Amyloidosis leads to deposits of abnormal protein in tissues and organs throughout the body. Some viral infections. Anorexia and bulimia nervosa may also cause gastroparesis over time as a complication. Gastroesophageal reflux disease. Abdominal migraine. Metabolic disorders including hypothyroidism or underactive thyroid functioning may also cause gastroparesis. Cancer radiation treatment applied over the chest or abdomen may also damage the nerves and lead to gastroparesis.

• #35 Gastroparesis – Symptoms, Causes, Treatments

  https://resources.healthgrades.com/right-care/digestive-health/gastroparesis

  Gastroparesis most likely results from damage to the nerves controlling the stomach muscles. The vagus nerve, in particular, is involved in signaling the stomach muscles to work. Sustaining damage to the vagus nerve can cause abnormal signaling and digestion delays. […] Some conditions linked to a higher chance of developing gastroparesis include: Diabetes: Chronically high blood sugar levels can damage nerves. Surgical complications: Trauma to the vagus nerve is a potential complication of surgery on the esophagus, stomach, or small intestine. Radiation exposure: Nerve damage from radiation to the chest or abdomen carries a risk of gastroparesis. Medication side effects: Narcotics, lithium, certain antidepressants, and other drugs are linked to gastroparesis, according to the American College of Gastroenterology. […] Also, females are more likely than males to develop gastroparesis.

• #36 Gastroparesis Causes, Symptoms, Diagnosis and Treatment – Cura4U

  https://cura4u.com/conditions/gastroparesis

  One of the major reasons for gastroparesis is an injury to your vagus nerve. The vagus nerve transmits signals from your brain to the digestive tract. These signals are responsible for the normal contraction of your gastrointestinal muscles for proper digestion. Damage to the vagus nerve can result in impaired or delayed signals which causes gastroparesis. Diabetes is considered an important causative factor of gastroparesis as it can damage the vagus nerve. […] Gastroparesis can also occur as a post-surgical complication if your vagus nerve gets damaged during the procedure. Many cases of this disease are also idiopathic, which means that no apparent cause can be identified. Other factors that may lead to gastroparesis include medications such as pain killers and antidepressants, viral infections, pregnancy, hypothyroidism, amyloidosis, and connective tissue diseases. Brainstem stroke and hypokalemia (low potassium level) are considered life-threatening causes of gastroparesis.

• #37 Gastroparesis for the nongastroenterologist | Cleveland Clinic Journal of Medicine

  https://www.ccjm.org/content/91/6/373

  Differences in the etiology of gastroparesis across countries can be partly explained by differences in the prevalence of diabetes mellitus, which is probably the most common cause where its prevalence is higher. […] Evidence regarding certain risk factors or causes of gastroparesis lacks consensus. […] Recent findings highlight that gastrointestinal motility disorders presenting with gastroparesis symptoms can occur in patients with generalized autoimmune dysautonomia.

• #38 Pediatric Gastroparesis – Conditions and Treatments | Children’s National Hospital

  https://www.childrensnational.org/get-care/health-library/gastroparesis

  Gastroparesis is caused when the vagus nerve is damaged or stops working. The vagus nerve controls how food moves through your digestive tract. When this nerve doesn’t work well, food moves too slowly or stops moving. […] The vagus nerve gets damaged if you have diabetes and your blood sugar or blood glucose levels stay high over a long period of time. […] Other causes of gastroparesis include: Eating disorders, such as anorexia or bulimia; Surgery on your stomach or vagus nerve; Extreme tiredness that does not seem to be caused by a health problem (chronic fatigue syndrome); Some medicines that slow movement in your intestine, such as narcotics for chronic pain; Disorders involving smooth muscle that may affect the stomach, such as amyloidosis and scleroderma; Nervous system disorders such as abdominal migraine and Parkinson’s disease; Metabolic disorders, which make the body have either too much or too little of essential things it needs to stay healthy, such as having too little of the thyroid hormone (hypothyroidism); A viral illness, such as a viral gastroenteritis.

• #39 Gastroparesis: Symptoms, Causes, & Advanced Treatment

  https://www.yashodahospitals.com/blog/gastroparesis-symptoms-causes-and-treatment/

  Certain viral infections affect the nerves governing stomach functions. […] Autoimmune disorders such as systemic lupus erythematosus and scleroderma can cause muscle and nerve damage in the GI tract. […] Pain relievers, antidepressants, and anticholinergic drugs, for example, are known to slow stomach emptying. […] Nervous system disorders such as Parkinson’s disease and multiple sclerosis might also damage nerves that regulate digestive system functions. […] Conditions such as anorexia and bulimia affect the digestive system’s normal functions. […] This is an underactive thyroid gland, slowing down bodily functions, including digestion.

• #40 Gastroparesis – Wikipedia

  https://en.wikipedia.org/wiki/Gastroparesis

  Gastroparesis may also be acquired after an infection or trauma, or it may be iatrogenic. […] The most commonly known cause is autonomic neuropathy of the vagus nerve, which innervates the stomach. Uncontrolled diabetes mellitus is a frequent cause of this nerve damage, but trauma to the vagus nerve is also possible. Some cases may be considered post-infectious. […] It is frequently caused by autonomic neuropathy, occurring in about 30-50% of people with long-standing type 1 or type 2 diabetes. In fact, diabetes mellitus has been named as the most common known cause of gastroparesis, as high levels of blood glucose may effect chemical changes in the nerves. […] Gastroparesis has been associated with connective tissue disorders such as Marfan syndrome, Loeys-Dietz syndrome and Ehlers-Danlos syndrome.

• #41 Causes of Gastroparesis | Gastroparesis Symptoms | Gastroparesis Clinic

  https://www.gastroparesis.mindovergut.com/causes-of-gastroparesis/

  In connective tissue disorders (e.g. scleroderma) the stomach muscles can degenerate and slow down gastric emptying. […] Women generally have a slower rate of gastric emptying than men. Gastric emptying is also affected by the menstrual cycle and is slower during the luteal phase of the cycle, which suggests that hormones might play a role in gastroparesis. […] A number of medications can slow down gastric emptying and lead to gastroparesis symptoms. […] Neurological conditions that may lead to gastroparesis include Parkinsons disease, multiple sclerosis, amyloidosis, and paraneoplastic disease. […] Psychological stress can have an impact on all systems in the body, including the gastrointestinal system.

• #42 How is Gastroparesis Detected and Treated – ADH – Windsor Center for Digestive Health

  https://windsordigestivehealth.com/how-is-gastroparesis-detected-and-treated/

  Gastroparesis is a common stomach disorder, especially in people who have had diabetes for a long time. It occurs when the stomach cannot empty properly, making the food pass through the stomach slower than usual. This condition is thought to result from a problem with the muscles and nerves that control stomach emptying. […] The most popular cause of gastroparesis is diabetes mellitus, a disease that damages the nerves that control the stomach muscles. This condition can also result from vagus nerve damage during stomach surgery. Occasionally, gastroparesis can result from nervous system reflexes like pancreas inflammation or pancreatitis. Scleroderma is also an example of diseases known to damage stomach muscles and causes gastroparesis. […] Other possible causes include mineral imbalances in the blood such as calcium, magnesium, and potassium, thyroid disease, and medications like oploids and some antidepressants. In some patients, the cause of gastroparesis may not be found. This condition is known as idiopathic gastroparesis.

• #43 Gastroparesis: Causes, symptoms, and natural remedies

  https://www.medicalnewstoday.com/articles/313873

  In gastroparesis, the muscles that move food from the stomach to the small intestine do not work effectively, and food takes too long to pass through the digestive system. […] The cause of gastroparesis is sometimes unknown, but some common risk factors include diabetes, multiple sclerosis (MS), and chemotherapy. […] The cause may be unknown in some cases, but certain factors that can increase the risk. […] These include: vagus nerve damage or surgery, uncontrolled diabetes, certain drugs or medications, such as tricyclic antidepressants, calcium channel blockers, clonidine, dopamine agonists, lithium, nicotine, and progesterone, conditions such as Parkinsons disease, multiple sclerosis, amyloidosis, and scleroderma, stomach surgery, viral infection, medical treatments such as radiation therapy, hypothyroidism, certain psychological disorders, eating disorders, cancer, chemotherapy, use of pain relief medications, such as codeine, anticholinergic drugs, which block nerve signals. […] At times, the cause of gastroparesis is unknown. These cases are referred to as idiopathic gastroparesis. Those at the highest risk for developing idiopathic gastroparesis include young and middle-aged women.

• #44 Gastroparesis – Gastric Diseases – Gastrointestinal Diseases – Gastroenterology – Diseases – McMaster Textbook of Internal Medicine

  https://empendium.com/mcmtextbook/chapter/B31.II.4.70.3.

  Gastroparesis is chronic delayed gastric emptying with no evidence of mechanical obstruction, resulting in food stasis in the stomach and gastric wall distention. […] Causes: 1) Frequent: Idiopathic gastroparesis (in ~20% of cases gastroparesis may be caused by infections with cytomegalovirus [CMV]; Epstein-Barr virus [EBV]; or human herpesvirus 3 [HHV3], also referred to as varicella-zoster virus (VZV)]) and diabetes (gastroparesis as a clinical manifestation of diabetic autonomic neuropathy). […] 2) Less frequent: Surgical complications after gastric or vagal surgery, drugs (eg, opioids, anticholinergic agents, glucagon-like peptide-1 [GLP-1] analogues), Parkinson disease, systemic sclerosis, systemic lupus erythematosus, paraneoplastic syndromes, amyloidosis, systemic mastocytosis, intestinal ischemia.

• #45 Gastroparesis (Causes, Symptoms, and Treatment) | Patient Leaflet

  https://patient.info/digestive-health/gastroparesis

  Gastroparesis is now more commonly known as delayed gastric emptying. It is a chronic condition in which food passes through the stomach and into the gut (intestine) more slowly than usual. The nerves that usually trigger the stomach muscles to move food out of the stomach and into the intestine don’t work as effectively as normal. This is not caused by an obstruction or structural abnormality but by a failure of the normal mechanisms. […] For many people with gastroparesis, there’s no obvious cause. This is called idiopathic gastroparesis – this appears to be the most common cause in the UK. However, smoking and chronic alcohol use are commonly associated with idiopathic gastroparesis. Cannabis has also been shown to delay gastric emptying. […] The most common cause is diabetes, especially poorly controlled diabetes. Over time, diabetes can cause damage to the stomach nerves. This is called diabetic gastroparesis. About 57 in 100 cases in the United States are due to diabetes although this number is lower in the UK. Gastroparesis can occur in type 1 diabetes or type 2 diabetes.

• #46 About gastroparesis and delayed gastric emptying | Children’s Wisconsin

  https://childrenswi.org/medical-care/gastroenterology-liver-and-nutrition-program/conditions/gastroparesis-and-delayed-gastric-emptying

  Gastroparesis, also known as delayed gastric emptying, is a motility disorder in which the stomach doesnt empty food as quickly as it should. […] Delayed gastric emptying can sometimes be the result of infections/inflammation, obstruction or, in very rare cases, neuropathy (nerve problems) due to diabetes or past surgeries. In most cases the cause of gastroparesis in pediatrics is idiopathic, which means unknown. […] Doctors dont know why some patients develop delayed gastric emptying after an infection. Some patients might be predisposed to developing this condition for reasons that are not yet known. […] The cause in children often remains unknown. Nerve damage due to long-standing diabetes or past surgeries is very rarely a cause of delayed gastric emptying in children.

• #47 Gastroparesis: A slow-emptying stomach can cause nausea and vomiting – Harvard Health

  https://www.health.harvard.edu/blog/gastroparesis-a-slow-emptying-stomach-can-cause-nausea-and-vomiting-202110272626

  Gastroparesis is a condition that causes delay in the emptying of the stomach. […] Most commonly, no clear cause for gastroparesis can be found among people who have the condition. […] Additionally, people are more likely to experience gastroparesis if they take certain medicines, such as opiate pain medications and some medications for diabetes, have had surgeries, radiation, or connective tissue disorders that affect the function of the nerves of the gut, or are female, because women are several times more likely than men to have gastroparesis. […] Thus far, there is limited information on health disparities among people with gastroparesis, although one study shows that diabetes is more likely to be the cause of gastroparesis among Black and Hispanic patients than white patients.

• #48 Gastroparesis | ACG

  https://gi.org/topics/gastroparesis/

  Gastroparesis is a chronic disorder which means delayed stomach emptying without a blockage. […] Diabetes is one of the more common causes. Gastroparesis may also occur after stomach surgery. Other causes include bacterial and viral infections. Narcotics, antidepressants and other medications which delay stomach emptying may also cause gastroparesis. There are a group of patients with gastroparesis where there is no obvious cause.

• #49 Gastroparesis | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/gastroparesis

  Most published literature describes gastroparesis as delayed gastric emptying without a mechanical obstruction. […] The exact cause of gastroparesis is unknown. The stomach is not paralyzed. Instead, gastroparesis seems to be both a muscle and sensory problem (neuromuscular disorder). […] Diabetes is the disease most frequently identified as a link to gastroparesis.

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