Wrzodziejące zapalenie jelita grubego
Zapobieganie i profilaktyka

Wrzodziejące zapalenie jelita grubego (WZJG) to przewlekła choroba zapalna o nie do końca poznanej etiologii, charakteryzująca się nawracającymi zaostrzeniami i remisjami. Profilaktyka WZJG obejmuje trzy poziomy: pierwotny (modyfikacja diety i stylu życia, np. dieta śródziemnomorska bogata w błonnik i kwasy omega-3, unikanie czerwonego mięsa i żywności przetworzonej, regularna aktywność fizyczna, unikanie palenia, odpowiedni sen, redukcja stresu), wtórny (wczesne wykrywanie choroby, szczególnie u osób z rodzinnym obciążeniem, oraz regularne kolonoskopie nadzorujące po 8-10 latach trwania choroby) oraz trzeciorzędowy (leczenie podtrzymujące remisję, głównie preparatami 5-ASA, które zmniejszają ryzyko zaostrzeń z 50-70% do około 30% rocznie i redukują ryzyko raka jelita grubego o 75%). Suplementacja wapnia, witaminy D, kwasów omega-3 oraz probiotyków może wspierać terapię, a profilaktyka przeciwzakrzepowa jest wskazana u hospitalizowanych pacjentów z WZJG ze względu na 1,5-3,5-krotnie wyższe ryzyko choroby zakrzepowo-zatorowej.

Wstęp do profilaktyki wrzodziejącego zapalenia jelita grubego

Wrzodziejące zapalenie jelita grubego (WZJG) jest przewlekłą chorobą zapalną jelita grubego charakteryzującą się nawracającymi epizodami zaostrzeń i remisji. Obecnie nie istnieje jednoznacznie skuteczna metoda zapobiegania rozwojowi WZJG, ponieważ etiologia choroby pozostaje nie w pełni poznana. Badania wskazują jednak na istnienie szeregu działań, które mogą zmniejszyć ryzyko wystąpienia choroby oraz zredukować częstotliwość zaostrzeń u osób z już rozpoznanym schorzeniem.12

Profilaktyka w WZJG może być rozpatrywana na trzech poziomach: pierwotnym (zapobieganie rozwojowi choroby), wtórnym (wczesne wykrywanie i leczenie) oraz trzeciorzędowym (zapobieganie powikłaniom u osób z już rozpoznaną chorobą). Celem kompleksowego podejścia do profilaktyki jest poprawa jakości życia pacjentów, zmniejszenie ryzyka hospitalizacji oraz zapobieganie powikłaniom długoterminowym.34

Pierwotna profilaktyka WZJG

Chociaż nie jest możliwe całkowite zapobieżenie rozwojowi wrzodziejącego zapalenia jelita grubego, istnieją czynniki modyfikowalne, które mogą zmniejszyć ryzyko jego wystąpienia. Dotyczy to szczególnie osób z czynnikami ryzyka, takimi jak rodzinne występowanie WZJG czy zaburzenia immunologiczne.5

Dieta i odżywianie w profilaktyce pierwotnej

Badania sugerują, że sposób odżywiania może wpływać na ryzyko rozwoju WZJG. Dieta bogata w warzywa, owoce, błonnik oraz niskotłuszczowa, podobna do diety śródziemnomorskiej, może zmniejszyć ryzyko zachorowania. Zaleca się:67

  • Zwiększenie spożycia żywności roślinnej i błonnika
  • Ograniczenie spożycia czerwonego mięsa
  • Unikanie żywności wysoko przetworzonej i dodatków do żywności
  • Włączenie produktów zawierających kwasy omega-3
  • Redukcję spożycia tłuszczów nasyconych

89

Dieta śródziemnomorska, bogata w rośliny, umiarkowana w ryby i nabiał, a uboga w mięso i żywność wysoko przetworzoną, jest zgodna z ogólnymi zaleceniami zdrowego odżywiania i może zmniejszać ryzyko rozwoju WZJG.10

Styl życia w profilaktyce pierwotnej

Oprócz diety, inne elementy stylu życia mogą odgrywać rolę w zapobieganiu WZJG:11

  • Regularna aktywność fizyczna – badania wskazują, że osoby regularnie ćwiczące mogą mieć mniejsze ryzyko rozwoju WZJG
  • Unikanie palenia tytoniu – chociaż w przypadku WZJG związek z paleniem jest złożony, ogólne korzyści zdrowotne z niepalenia przewyższają potencjalne efekty ochronne
  • Odpowiedni sen – zapewnienie wystarczającej ilości snu wydaje się być korzystne dla zdrowia przewodu pokarmowego
  • Zarządzanie stresem – techniki redukcji stresu mogą korzystnie wpływać na zdrowie jelit
  • Ograniczenie stosowania antybiotyków – przede wszystkim ich racjonalne stosowanie zgodnie z zaleceniami lekarskimi

1213

Inne czynniki w profilaktyce pierwotnej

Badania sugerują również, że karmienie piersią w okresie niemowlęcym może zmniejszyć ryzyko rozwoju WZJG u dzieci. Jest to kolejny argument przemawiający za popularyzacją karmienia naturalnego.14

Warto również zwrócić uwagę na potencjalną rolę probiotyków w utrzymaniu zdrowej mikrobioty jelitowej, chociaż dane dotyczące ich skuteczności w pierwotnej profilaktyce WZJG są ograniczone.15

Wtórna profilaktyka – wczesne wykrywanie i leczenie

Profilaktyka wtórna koncentruje się na wczesnym wykrywaniu choroby, co umożliwia szybkie wdrożenie odpowiedniego leczenia i może spowolnić progresję choroby oraz zmniejszyć ryzyko powikłań.16

Znaczenie wczesnej diagnostyki

Wczesne wykrycie wrzodziejącego zapalenia jelita grubego ma kluczowe znaczenie dla skutecznego leczenia i zapobiegania poważnym powikłaniom. Osoby z objawami sugerującymi WZJG, takimi jak przewlekła biegunka, bóle brzucha, krwawienie z odbytu czy niewyjaśniona utrata masy ciała, powinny szybko skonsultować się z lekarzem.17

Szczególną uwagę należy zwrócić na osoby z rodzinnym występowaniem nieswoistych chorób zapalnych jelit, które powinny być świadome podwyższonego ryzyka i czujnie obserwować potencjalne objawy.18

Badania przesiewowe

Badania przesiewowe są szczególnie istotne w przypadku osób z długotrwałym WZJG ze względu na zwiększone ryzyko raka jelita grubego. Zgodnie z zaleceniami, pacjenci z rozpoznanym WZJG trwającym 8-10 lat lub dłużej powinni być poddawani regularnym kolonoskopiom nadzorującym.1920

U pacjentów z pierwotnym stwardniającym zapaleniem dróg żółciowych (PSC) oraz WZJG, badania przesiewowe powinny rozpocząć się od momentu rozpoznania obu chorób ze względu na szczególnie wysokie ryzyko raka jelita grubego w tej grupie.21

Trzeciorzędowa profilaktyka – zapobieganie zaostrzeniom

U pacjentów z rozpoznanym WZJG, kluczowe znaczenie ma zapobieganie zaostrzeniom choroby oraz powikłaniom długoterminowym.22

Leczenie podtrzymujące remisję

Podstawą profilaktyki trzeciorzędowej jest odpowiednie leczenie farmakologiczne podtrzymujące remisję. Regularne przyjmowanie przepisanych leków, nawet w okresie bezobjawowym, jest kluczowe dla utrzymania kontroli nad chorobą.2324

Preparaty 5-ASA (kwasu 5-aminosalicylowego), takie jak mesalazyna, są podstawowymi lekami stosowanymi w podtrzymywaniu remisji WZJG. Badania wskazują, że regularne stosowanie tych leków zmniejsza ryzyko zaostrzeń z 50-70% do około 30% rocznie.25

Warto podkreślić, że długotrwałe stosowanie preparatów 5-ASA może również zmniejszać ryzyko rozwoju raka jelita grubego u pacjentów z WZJG. W jednym z badań regularne stosowanie mesalazyny wiązało się z 75% redukcją ryzyka rozwoju raka jelita grubego.2627

U pacjentów z nietolerancją lub brakiem odpowiedzi na 5-ASA, alternatywnymi opcjami terapeutycznymi mogą być leki immunomodulujące, leki biologiczne lub drobnocząsteczkowe inhibitory kinaz janusowych.28

Dieta i styl życia w zapobieganiu zaostrzeniom

Zmiany w sposobie odżywiania i stylu życia mogą pomóc w kontrolowaniu objawów WZJG i wydłużyć czas między zaostrzeniami.29

Rekomendacje dietetyczne obejmują:3031

  • Identyfikację i unikanie indywidualnych czynników wyzwalających objawy (prowadzenie dziennika żywieniowego)
  • Spożywanie mniejszych, częstszych posiłków zamiast kilku obfitych
  • Ograniczenie produktów mlecznych w przypadku nietolerancji laktozy
  • Unikanie napojów gazowanych
  • Ograniczenie produktów wysokobłonnikowych podczas zaostrzeń (popcorn, skórki warzyw, orzechy)
  • Zwiększenie spożycia płynów, szczególnie wody
  • Unikanie NLPZ (niesteroidowych leków przeciwzapalnych) u osób, u których te leki mogą powodować zaostrzenia

3233

W okresie remisji korzystne może być stopniowe włączanie większej ilości błonnika w postaci dobrze tolerowanych warzyw i owoców, co sprzyja zdrowiu mikrobioty jelitowej.34

W zakresie stylu życia zaleca się:3536

  • Regularne ćwiczenia fizyczne o niskiej intensywności (spacery, pływanie, jazda na rowerze, joga)
  • Techniki redukcji stresu (głębokie oddychanie, medytacja, aktywność fizyczna)
  • Zapewnienie odpowiedniej ilości snu
  • Unikanie palenia tytoniu
  • Udział w grupach wsparcia dla pacjentów z WZJG

3738

Rola suplementacji i probiotyków

Suplementacja może być korzystna w zapobieganiu niedoborom i poprawie ogólnego stanu zdrowia u pacjentów z WZJG:39

  • Wapń i witamina D – szczególnie u pacjentów stosujących przewlekle glikokortykosteroidy, w celu zapobiegania osteoporozie
  • Kwasy omega-3 – mogą wykazywać działanie przeciwzapalne
  • Probiotyki – badania sugerują, że niektóre szczepy mogą być pomocne w podtrzymywaniu remisji WZJG

4041

Niektóre badania wykazały, że probiotyki mogą być równie skuteczne jak preparaty 5-ASA w zapobieganiu nawrotom w nieaktywnym WZJG, jednak dane te wymagają potwierdzenia w dalszych badaniach.42

Preparat VSL#3 (mieszanka probiotyczna) wykazał skuteczność w indukowaniu remisji w aktywnym WZJG, co sugeruje potencjalną rolę w terapii podtrzymującej.43

Profilaktyka powikłań WZJG

Profilaktyka zakrzepowo-zatorowa

Pacjenci z WZJG mają 1,5-3,5-krotnie wyższe ryzyko rozwoju choroby zakrzepowo-zatorowej w porównaniu do populacji ogólnej. Wytyczne kliniczne zalecają farmakologiczną profilaktykę przeciwzakrzepową u hospitalizowanych pacjentów z WZJG.44

Profilaktyka przeciwzakrzepowa powinna być stosowana u pacjentów z WZJG podczas hospitalizacji z jakiejkolwiek przyczyny. Zaleca się stosowanie heparyny drobnocząsteczkowej lub fondaparynuksu zamiast heparyny niefrakcjonowanej w niskich dawkach.45

U ambulatoryjnych pacjentów z aktywnym WZJG i dodatkowymi czynnikami ryzyka żylnej choroby zakrzepowo-zatorowej należy rozważyć profilaktykę przeciwzakrzepową i kontynuować ją do czasu osiągnięcia remisji.46

Co istotne, profilaktyka przeciwzakrzepowa nie zwiększa ryzyka dalszego krwawienia z przewodu pokarmowego związanego z aktywnym WZJG.47

Profilaktyka osteoporozy

Pacjenci z WZJG, szczególnie ci przewlekle stosujący glikokortykosteroidy, są narażeni na zwiększone ryzyko osteoporozy. W celu zapobiegania temu powikłaniu zaleca się:4849

  • Badanie densytometryczne (DXA) u pacjentów stosujących przewlekle steroidy
  • Suplementację wapnia i witaminy D
  • Rozważenie stosowania bisfosfonianów u pacjentów z czynnikami ryzyka
  • Regularne ćwiczenia z obciążeniem
  • Ograniczenie stosowania steroidów do minimum

5051

Profilaktyka nowotworów

Pacjenci z długotrwałym WZJG mają zwiększone ryzyko rozwoju raka jelita grubego. Kluczowe elementy profilaktyki onkologicznej obejmują:5253

  • Regularne badania endoskopowe (kolonoskopie nadzorujące) rozpoczynające się po 8-10 latach trwania choroby
  • Kontrolę stanu zapalnego jelita poprzez odpowiednie leczenie (długotrwały stan zapalny zwiększa ryzyko zmian przednowotworowych)
  • Stosowanie preparatów 5-ASA, które mogą wykazywać działanie chemoprewencyjne

5455

Ponadto, pacjenci z WZJG mają zwiększone ryzyko rozwoju nowotworów skóry, szczególnie podczas stosowania terapii immunosupresyjnych. Zaleca się regularne badania dermatologiczne oraz stosowanie kremów z filtrem UV.5657

U kobiet stosujących leki immunosupresyjne zaleca się coroczne badania cytologiczne w celu wczesnego wykrycia raka szyjki macicy.58

Szczepienia ochronne u pacjentów z WZJG

Pacjenci z WZJG, szczególnie ci leczeni immunosupresyjnie, mają zwiększone ryzyko zakażeń, którym można zapobiec poprzez szczepienia. Zaleca się:59

  • Szczepienia przeciwko grypie (coroczne)
  • Szczepienia przeciwko pneumokokom
  • Szczepienia przeciwko półpaścowi (u pacjentów leczonych immunosupresyjnie)
  • Aktualizację pozostałych szczepień zgodnie z kalendarzem szczepień

6061

Należy pamiętać, że szczepionki żywe są przeciwwskazane u pacjentów stosujących leczenie immunosupresyjne lub powinny być podane z zachowaniem odpowiedniego odstępu czasowego od rozpoczęcia takiej terapii.62

Obiecujące kierunki w profilaktyce WZJG

Nutraceutyki i naturalne związki przeciwzapalne

Badania nad naturalnymi związkami o właściwościach przeciwzapalnych sugerują ich potencjalną rolę w profilaktyce i leczeniu WZJG:6364

  • Kurkumina (aktywny składnik kurkumy) – badania kliniczne wykazały, że jednoczesne podawanie kurkuminy z konwencjonalnymi lekami było skuteczne, dobrze tolerowane i traktowane jako bezpieczny środek do utrzymania remisji, zapobiegania nawrotom i poprawy wskaźnika aktywności klinicznej
  • Olej kokosowy – badania na modelach zwierzęcych sugerują potencjalne działanie ochronne dzięki właściwościom przeciwzapalnym i antyoksydacyjnym
  • Fruktany typu inulinowego (prebiotyki) – badania sugerują, że mogą zmniejszać nasilenie biochemicznego nawrotu choroby

656667

Naturalne składniki często posiadają właściwości przeciwutleniające, przeciwzapalne i immunomodulujące, co czyni je potencjalnymi kandydatami do wspomagania profilaktyki i leczenia WZJG.68

Dieta roślinna w profilaktyce i leczeniu

Badania sugerują, że dieta roślinna może znacząco zmniejszyć ryzyko nawrotu u pacjentów z WZJG, z skutecznością porównywalną do mesalazyny. Może być stosowana jako monoterapia lub jako uzupełnienie standardowego leczenia farmakologicznego.6970

Zalety diety roślinnej obejmują:71

  • Brak przeciwwskazań i działań niepożądanych
  • Przystępność cenowa
  • Możliwość zapobiegania i leczenia chorób współistniejących (cukrzyca typu 2, choroba wieńcowa)
  • Zmniejszenie ryzyka raka jelita grubego

72

Znaczenie współpracy pacjenta i zespołu medycznego

Kompleksowa profilaktyka WZJG wymaga ścisłej współpracy pomiędzy pacjentem a zespołem medycznym, w tym gastroenterologiem i lekarzem podstawowej opieki zdrowotnej.7374

Kluczowe elementy skutecznej współpracy obejmują:75

  • Regularne wizyty kontrolne, co najmniej raz w roku
  • Przestrzeganie zaleceń dotyczących przyjmowania leków
  • Monitorowanie objawów i szybkie reagowanie na zaostrzenia
  • Regularną ocenę aktywności choroby za pomocą biomarkerów i oceny objawów
  • Wdrażanie indywidualnego planu profilaktyki uwzględniającego wszystkie poziomy działań prewencyjnych

7677

Szczególną uwagę należy zwrócić na młodych pacjentów z WZJG, u których odnotowuje się niski poziom przestrzegania zaleceń terapeutycznych. Badania wskazują, że prawie 70% nastolatków i młodych dorosłych z wrzodziejącym zapaleniem jelita grubego przestaje przyjmować leki w ciągu roku od rozpoznania, co zwiększa ryzyko nawrotów i poważnych powikłań.7879

Indywidualizacja działań profilaktycznych

Ze względu na heterogenność WZJG, indywidualizacja działań profilaktycznych jest kluczowa dla osiągnięcia optymalnych wyników terapeutycznych. Każdy pacjent może mieć inne czynniki wyzwalające zaostrzenia, różną odpowiedź na leki oraz odmienne preferencje dotyczące diety i stylu życia.8081

Zaleca się prowadzenie dziennika objawów i czynników wyzwalających, co pomaga w identyfikacji indywidualnych wzorców choroby i dostosowaniu strategii profilaktycznych.82

W przypadku zmian w diecie, stylu życia czy suplementacji, istotne jest konsultowanie ich z lekarzem prowadzącym, aby upewnić się, że są one bezpieczne i wspierają ogólny plan leczenia.83

Wnioski i przyszłe kierunki profilaktyki

Choć nie istnieje obecnie jednoznacznie skuteczna metoda zapobiegania rozwojowi wrzodziejącego zapalenia jelita grubego, wielopoziomowe podejście do profilaktyki może znacząco poprawić jakość życia pacjentów i zmniejszyć ryzyko powikłań.84

Skuteczna profilaktyka WZJG obejmuje:85

  • Modyfikację diety i stylu życia w celu zmniejszenia ryzyka rozwoju choroby
  • Wczesne wykrywanie i leczenie choroby
  • Odpowiednie leczenie podtrzymujące remisję
  • Zapobieganie powikłaniom długoterminowym
  • Regularne badania kontrolne i monitorowanie stanu zdrowia

86

Przyszłe kierunki badań w zakresie profilaktyki WZJG obejmują identyfikację biomarkerów predykcyjnych, rozwój nowych terapii prewencyjnych oraz dalsze badania nad rolą diety, mikrobioty jelitowej i środowiska w patogenezie choroby.87

Kompleksowe podejście do profilaktyki WZJG, uwzględniające wszystkie trzy poziomy działań prewencyjnych, może znacząco poprawić jakość życia pacjentów i zmniejszyć obciążenie związane z chorobą zarówno dla pacjentów, jak i dla systemu opieki zdrowotnej.88

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  1. 10.04.2026
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Materiały źródłowe

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    https://www.cedars-sinai.org/health-library/diseases-and-conditions/u/ulcerative-colitis.html
    Experts dont know what causes ulcerative colitis. They also dont know how to prevent the disease. […] But good nutrition can play an important role in managing the disease. Changes in diet can help reduce symptoms. Some of the dietary changes that may be advised include: Not drinking carbonated drinks, Not eating high-fiber foods such as popcorn, vegetable skins, and nuts while you have symptoms, Drinking more liquids, Eating more frequent, smaller meals, Keeping a food diary that identifies foods that cause symptoms. […] In some cases, your provider may ask you to avoid taking NSAIDs, pain medicines such as ibuprofen, naproxen, or similar. This is because these medicines can cause the ulcerative colitis to flare in some people.
  • #2 Ulcerative Colitis Prevention: How To Reduce Risk
    https://www.health.com/ulcerative-colitis-prevention-8633457
    There is no known way to prevent ulcerative colitis. However, there are things you can do to lower your risk of developing the condition, including taking measures to protect your gut health. This is especially true if you have known risk factors, such as a family history of UC or a diet high in processed foods. […] There is no guaranteed way to prevent ulcerative colitis, but certain lifestyle habits may help lower your risk. Meanwhile, screening tests can help detect ulcerative colitis early so you can begin treatment, which may slow disease progression and reduce your risk of complications. […] While there is no guaranteed way to prevent ulcerative colitis, prioritizing lifestyle habits like eating a nutritious diet, regularly exercising, and practicing stress management techniques can support your gut health and may lower your risk. […] If you are concerned about your risk, particularly if you have a family history of ulcerative colitis, talk to your healthcare provider. They can create a plan that promotes a healthy gut and may help protect against developing ulcerative colitis.
  • #3 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro
    https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/
    Patients with inflammatory bowel disease (IBD) are subject to complications from the disease itself and also from the immunosuppressive therapies used for treatment. […] To optimize the care of patients with IBD, providers need to consider primary, secondary and tertiary prevention. […] Primary prevention is defined as prevention of disease development. […] As compared to the age-matched general population, patients with IBD are at increased risk for vaccine-preventable illnesses, such as influenza, pneumococcal pneumonia, and shingles. […] Therefore, adherence to vaccination guidelines of inactivated vaccines can reduce these infectious complications. […] Another method of primary prevention in IBD patients is sunscreen use to prevent skin cancer. […] Therefore, this is a potentially preventable complication of therapy through broad-spectrum sunscreen use.
  • #4 Preventive health measures in inflammatory bowel disease
    https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/
    We aim to review the literature and provide guidance on preventive health measures in inflammatory bowel disease (IBD). […] Preventive health measures can avert morbidity and improve the quality of life of patients with IBD. Gastroenterologists and primary care physicians (PCPs) should have an up to date working knowledge of preventive health measures for IBD patients. A holistic approach and better communication between gastroenterologists and PCPs with explicit clarification of roles will prevent duplication of services and streamline care. […] Effective preventive measures to reduce morbidity, hospitalization, and surgery are critical to improving disease free remission and quality of life. […] Therefore, gastroenterologists need to take a proactive role in the preventive health care needs of IBD patients by clarifying with each patient the limits of responsibility for preventive health and alerting PCPs to the unique health maintenance needs of IBD patients.
  • #5 Ulcerative Colitis Prevention: How To Reduce Risk
    https://www.health.com/ulcerative-colitis-prevention-8633457
    There is no known way to prevent ulcerative colitis. However, there are things you can do to lower your risk of developing the condition, including taking measures to protect your gut health. This is especially true if you have known risk factors, such as a family history of UC or a diet high in processed foods. […] There is no guaranteed way to prevent ulcerative colitis, but certain lifestyle habits may help lower your risk. Meanwhile, screening tests can help detect ulcerative colitis early so you can begin treatment, which may slow disease progression and reduce your risk of complications. […] While there is no guaranteed way to prevent ulcerative colitis, prioritizing lifestyle habits like eating a nutritious diet, regularly exercising, and practicing stress management techniques can support your gut health and may lower your risk. […] If you are concerned about your risk, particularly if you have a family history of ulcerative colitis, talk to your healthcare provider. They can create a plan that promotes a healthy gut and may help protect against developing ulcerative colitis.
  • #6 Role of diet in prevention versus treatment of Crohn’s disease and ulcerative colitis | Frontline Gastroenterology
    https://fg.bmj.com/content/15/3/247
    Diet is a modifiable risk factor for disease course and data over the past decade have emerged to indicate its role in Crohns disease (CD) and ulcerative colitis (UC). […] We appraise the literature for how our dietary recommendations should be shaped to prevent disease development and if or how that differs for CD and UC induction therapy and maintenance therapy. In UC, principles of healthy eating are likely to play a role in all states of disease. […] Features of healthy eating are associated with prevention of Crohns disease, but less certain for ulcerative colitis. […] The role of diet to maintain remission in Crohns disease and ulcerative colitis is unknown, so default to healthy eating guidelines is recommended. […] Identifying modifiable risk factors in the pathogenesis of IBD is appealing to prevent IBD in the general population and specifically in those at high risk, including first-degree relatives of patients with IBD.
  • #7 Role of diet in prevention versus treatment of Crohn’s disease and ulcerative colitis | Frontline Gastroenterology
    https://fg.bmj.com/content/15/3/247
    Establishing the role of diet in IBD prevention is determined via large prospective cohort studies that assess diet through dietary questionnaires in a healthy population that is followed forward. […] The general message that features of a MED that is heavily plant based, moderate in fish and dairy and low in meat and UPF is pleasingly in line with healthy eating guidelines and assurance that these default dietary recommendations are likely to reduce risk of CD development. […] While dietary associations for UC development are less apparent, with the exception of red meat consumption increasing risk, it is judicious to recommend the same for those at risk of UC. […] Such advice should remain for active and quiescent UC in the absence of high-quality trials that indicate otherwise.
  • #8 Can You Prevent Inflammatory Bowel Disease? | Mass General Brigham
    https://www.massgeneralbrigham.org/en/about/newsroom/articles/prevent-inflammatory-bowel-disease
    Theres no known way to prevent IBD. But there may be things you can do to help reduce your risk. […] To help reduce your risk of developing IBD: Avoid processed food and additives. Eat a Mediterranean-style diet rich in fruits and vegetables. Get enough sleep. Limit exposure to antibiotics. Dont smoke. Reduce stress and anxiety. Breastfeeding during infancy has been shown to reduce risk of IBD in children. Studies also have shown that people who exercise regularly may have a lower risk of developing IBD.
  • #9 Role of diet in prevention versus treatment of Crohn’s disease and ulcerative colitis | Frontline Gastroenterology
    https://fg.bmj.com/content/15/3/247
    Establishing the role of diet in IBD prevention is determined via large prospective cohort studies that assess diet through dietary questionnaires in a healthy population that is followed forward. […] The general message that features of a MED that is heavily plant based, moderate in fish and dairy and low in meat and UPF is pleasingly in line with healthy eating guidelines and assurance that these default dietary recommendations are likely to reduce risk of CD development. […] While dietary associations for UC development are less apparent, with the exception of red meat consumption increasing risk, it is judicious to recommend the same for those at risk of UC. […] Such advice should remain for active and quiescent UC in the absence of high-quality trials that indicate otherwise.
  • #10 Role of diet in prevention versus treatment of Crohn’s disease and ulcerative colitis | Frontline Gastroenterology
    https://fg.bmj.com/content/15/3/247
    Establishing the role of diet in IBD prevention is determined via large prospective cohort studies that assess diet through dietary questionnaires in a healthy population that is followed forward. […] The general message that features of a MED that is heavily plant based, moderate in fish and dairy and low in meat and UPF is pleasingly in line with healthy eating guidelines and assurance that these default dietary recommendations are likely to reduce risk of CD development. […] While dietary associations for UC development are less apparent, with the exception of red meat consumption increasing risk, it is judicious to recommend the same for those at risk of UC. […] Such advice should remain for active and quiescent UC in the absence of high-quality trials that indicate otherwise.
  • #11 Can You Prevent Inflammatory Bowel Disease? | Mass General Brigham
    https://www.massgeneralbrigham.org/en/about/newsroom/articles/prevent-inflammatory-bowel-disease
    Theres no known way to prevent IBD. But there may be things you can do to help reduce your risk. […] To help reduce your risk of developing IBD: Avoid processed food and additives. Eat a Mediterranean-style diet rich in fruits and vegetables. Get enough sleep. Limit exposure to antibiotics. Dont smoke. Reduce stress and anxiety. Breastfeeding during infancy has been shown to reduce risk of IBD in children. Studies also have shown that people who exercise regularly may have a lower risk of developing IBD.
  • #12 Can You Prevent Inflammatory Bowel Disease? | Mass General Brigham
    https://www.massgeneralbrigham.org/en/about/newsroom/articles/prevent-inflammatory-bowel-disease
    Theres no known way to prevent IBD. But there may be things you can do to help reduce your risk. […] To help reduce your risk of developing IBD: Avoid processed food and additives. Eat a Mediterranean-style diet rich in fruits and vegetables. Get enough sleep. Limit exposure to antibiotics. Dont smoke. Reduce stress and anxiety. Breastfeeding during infancy has been shown to reduce risk of IBD in children. Studies also have shown that people who exercise regularly may have a lower risk of developing IBD.
  • #13 11 Tips to Prevent an Ulcerative Colitis Flare – Canadian Digestive Health Foundation
    https://cdhf.ca/en/11-tips-to-prevent-an-ulcerative-colitis-flare/
    Please note: This article outlines 11 tips to help you prevent an ulcerative colitis flare, and is based on one patient’s experience. Nothing in this article is meant to replace any advice you have received from your doctor. […] Even during periods of remission, we still need to take daily measures to ensure that we prevent any potential flare-ups. […] The first tip to help you prevent an ulcerative colitis flare-up is to ensure that you get enough sleep. […] The second tip to help you prevent an ulcerative colitis flare-up is to ensure that you learn how to identify daily stressors so that you may eliminate them. […] Tip number three to help you prevent an ulcerative colitis flare-up: Always make time for things that make you happy. […] The fourth tip to help you prevent an ulcerative colitis flare-up: Be with people that make you happy, promote your mental health, and who inspires you to be healthier or happier.
  • #14 Can You Prevent Inflammatory Bowel Disease? | Mass General Brigham
    https://www.massgeneralbrigham.org/en/about/newsroom/articles/prevent-inflammatory-bowel-disease
    Theres no known way to prevent IBD. But there may be things you can do to help reduce your risk. […] To help reduce your risk of developing IBD: Avoid processed food and additives. Eat a Mediterranean-style diet rich in fruits and vegetables. Get enough sleep. Limit exposure to antibiotics. Dont smoke. Reduce stress and anxiety. Breastfeeding during infancy has been shown to reduce risk of IBD in children. Studies also have shown that people who exercise regularly may have a lower risk of developing IBD.
  • #15 Double blind placebo-controlled trial for the prevention of ulcerative colitis relapses by β-fructan prebiotics: efficacy and metabolomic analysis | medRxiv
    https://www.medrxiv.org/content/10.1101/2022.01.16.22269376.full
    Ulcerative colitis (UC) is associated with altered intestinal microbiome (dysbiosis), most significantly, reduced strict butyrate-producing anaerobes and increased facultative anaerobes. Inulin-type prebiotics appear to reduce and prevent colitis in preclinical studies and small clinical trials. However, these results need to be validated in randomized controlled clinical trial (RCT) studies. […] The aim of this RCT study was to assess the efficacy of -fructans (oligofructose and inulin) in preventing relapses in UC patients in clinical remission as well as identify potential mechanisms of activity. […] Consumption of inulin-type -fructans did not prevent clinical relapse in UC patients who were in clinical remission, however it significantly reduced risk of relapse, defined by increased FCP (subclinical or biochemical colonic inflammation).
  • #16 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro
    https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/
    Finally, weight bearing exercise and calcium/ vitamin D supplementation, when appropriate, can prevent downstream osteoporotic fracture in these patients who may require recurrent courses of corticosteroids during their lifetimes with IBD. […] Secondary prevention is defined as detecting a disease early to prevent disability; such as through screening programs. […] Therefore, there are a number of important opportunities for secondary prevention in IBD patients. […] Therefore, a dermatology skin screening program is recommended in all patients with IBD. […] Annual cervical cancer screening is recommended in patients with IBD on immunosuppression. […] Therefore, patients with longstanding colonic inflammation should undergo routine colonoscopy starting at 8-10 years of colonic disease duration, with subsequent colonoscopy intervals based on the results (often every 1-3 years).
  • #17 Raising Awareness for Treatment and Prevention of Ulcerative Colitis
    https://gatgi.com/blog/raising-awareness-for-treatment-and-prevention-of-ulcerative-colitis/
    Ulcerative colitis is a chronic disease of the large intestine, or colon, in which the lining of the colon becomes inflamed and develops tiny open sores or ulcers. This can cause discomfort and frequent emptying of the colon. By increasing awareness about this condition, we can potentially prevent its onset and effectively manage its impact. […] Early detection of ulcerative colitis can greatly influence the management and progression of the disease. Detecting the disease in its initial stages allows for a more effective treatment strategy, potentially reducing flare-ups and promoting a better quality of life. Awareness of the symptoms and seeking prompt medical attention when they appear is key to early detection. […] Understanding these contributing elements can lead to effective prevention strategies and improved treatment options, highlighting the importance of continued research in this area.
  • #18 Ulcerative Colitis Prevention: How To Reduce Risk
    https://www.health.com/ulcerative-colitis-prevention-8633457
    There is no known way to prevent ulcerative colitis. However, there are things you can do to lower your risk of developing the condition, including taking measures to protect your gut health. This is especially true if you have known risk factors, such as a family history of UC or a diet high in processed foods. […] There is no guaranteed way to prevent ulcerative colitis, but certain lifestyle habits may help lower your risk. Meanwhile, screening tests can help detect ulcerative colitis early so you can begin treatment, which may slow disease progression and reduce your risk of complications. […] While there is no guaranteed way to prevent ulcerative colitis, prioritizing lifestyle habits like eating a nutritious diet, regularly exercising, and practicing stress management techniques can support your gut health and may lower your risk. […] If you are concerned about your risk, particularly if you have a family history of ulcerative colitis, talk to your healthcare provider. They can create a plan that promotes a healthy gut and may help protect against developing ulcerative colitis.
  • #19 Ulcerative Colitis – Harvard Health
    https://www.health.harvard.edu/a_to_z/ulcerative-colitis-a-to-z
    There is no way to prevent ulcerative colitis. […] However, some people are able to decrease the frequency of symptoms. They do this by avoiding foods that seem to provoke flare-ups. For some people with ulcerative colitis, this includes spicy foods and milk products. […] If you have ulcerative colitis, you can decrease the toll it takes on your body. To do this, eat a well-balanced, nutritious diet especially when you are not having symptoms such as poor appetite and nausea that make it hard to eat. By doing so, you can decrease complications from malnutrition, such as weight loss or a low blood count. […] Ulcerative colitis increases your risk of colon cancer. People with extensive inflammation in the whole colon have the highest risk. It is important to have your colon checked frequently for early signs of cancer. Ask your doctor how often you should have a colonoscopy. […] Poor nutrition or the effect of colitis medicines can lead to osteoporosis. This disease weakens bones and can cause bones to break. Osteoporosis can be prevented with medicines, adequate exercise, calcium, and vitamin D. If you have ulcerative colitis, discuss osteoporosis with your doctor.
  • #20 Ulcerative Colitis: Rapid Evidence Review | AAFP
    https://www.aafp.org/pubs/afp/issues/2022/0400/p406.html
    Colonoscopy is recommended starting eight years after diagnosis of ulcerative colitis or immediately if primary sclerosing cholangitis is also present because of an increased risk of colorectal cancer. Interval surveillance in those with disease proximal to the sigmoid colon should occur every one to three years based on risk factors and prior endoscopy findings, with annual colonoscopies in patients with concomitant primary sclerosing cholangitis, due to very high risk of developing colorectal cancer.
  • #21 Ulcerative Colitis: Rapid Evidence Review | AAFP
    https://www.aafp.org/pubs/afp/issues/2022/0400/p406.html
    Colonoscopy is recommended starting eight years after diagnosis of ulcerative colitis or immediately if primary sclerosing cholangitis is also present because of an increased risk of colorectal cancer. Interval surveillance in those with disease proximal to the sigmoid colon should occur every one to three years based on risk factors and prior endoscopy findings, with annual colonoscopies in patients with concomitant primary sclerosing cholangitis, due to very high risk of developing colorectal cancer.
  • #22 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro
    https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/
    Therefore, screening with DEXA scan for these individuals and in women age 65 years is recommended. […] Tertiary prevention refers to utilization of measures to reduce the impact of long-term disease and disability. […] Therefore, by intervening early and treating inflammation, with a goal of mucosal healing, we can potentially prevent these morbid and potentially life-threatening, complications of IBD. […] Therefore, by optimizing therapies to improve mucosal healing, we may be able to impact the long-term disability associated with irreversible bowel damage in IBD. […] Through this partnership, an individualized plan for preventive medicine can be developed for each patient with IBD. […] By focusing on implementing the three forms of prevention: primary, secondary, and tertiary, we can improve the lives of our patients with IBD.
  • #23 Ulcerative Colitis: How to Prevent and Manage Flare-Ups
    https://www.webmd.com/ibd-crohns-disease/ulcerative-colitis/managing-ulcerative-colitis
    Take your UC medications exactly as prescribed. It’s one of the best things you can do to manage ulcerative colitis and prevent flares. […] You may have heard about diets for people with ulcerative colitis. There’s no evidence that certain foods can cause UC, cure it, or set off a flare. But if you’re having a flare, what you eat and drink can make symptoms worse: […] When you’re having a flare: Eat smaller meals eaten more often. It may be easier on your system. […] Talk to your doctor to see if they recommend you take supplements. You could think about seeing a nutritionist, too. They can come up with an eating plan that works for you. […] It won’t stop flare-ups from happening, but being active can improve your overall health, lift your mood, boost your immune system, and prevent some complications of the disease.
  • #24 Ulcerative Colitis: Causes, Symptoms, and Treatment
    https://patient.info/digestive-health/inflammatory-bowel-disease/ulcerative-colitis
    Ulcerative colitis is a disease where inflammation develops in the colon and the rectum (the large intestine). […] The disease can often be prevented from flaring up by taking medication, usually mesalazine, each day. […] Once an initial flare-up of symptoms has cleared, you will usually be advised to take a medicine each day to prevent further flare-ups. […] If you have ulcerative colitis and do not take a regular preventative medicine, you have about a 5-7 in 10 chance of having at least one flare-up each year. This is reduced to about a 3 in 10 chance if you take a preventative medicine each day. […] An aminosalicylate medicine, usually mesalazine (described above), is commonly used to prevent flare-ups. […] Recent studies indicate that the risk of cancer is reduced in people who take regular long-term aminosalicylate medication (described above). In one study, people with ulcerative colitis who regularly took mesalazine had a 75% reduced risk of developing colon cancer.
  • #25 Ulcerative Colitis: Causes, Symptoms, and Treatment
    https://patient.info/digestive-health/inflammatory-bowel-disease/ulcerative-colitis
    Ulcerative colitis is a disease where inflammation develops in the colon and the rectum (the large intestine). […] The disease can often be prevented from flaring up by taking medication, usually mesalazine, each day. […] Once an initial flare-up of symptoms has cleared, you will usually be advised to take a medicine each day to prevent further flare-ups. […] If you have ulcerative colitis and do not take a regular preventative medicine, you have about a 5-7 in 10 chance of having at least one flare-up each year. This is reduced to about a 3 in 10 chance if you take a preventative medicine each day. […] An aminosalicylate medicine, usually mesalazine (described above), is commonly used to prevent flare-ups. […] Recent studies indicate that the risk of cancer is reduced in people who take regular long-term aminosalicylate medication (described above). In one study, people with ulcerative colitis who regularly took mesalazine had a 75% reduced risk of developing colon cancer.
  • #26 Ulcerative Colitis: Causes, Symptoms, and Treatment
    https://patient.info/digestive-health/inflammatory-bowel-disease/ulcerative-colitis
    Ulcerative colitis is a disease where inflammation develops in the colon and the rectum (the large intestine). […] The disease can often be prevented from flaring up by taking medication, usually mesalazine, each day. […] Once an initial flare-up of symptoms has cleared, you will usually be advised to take a medicine each day to prevent further flare-ups. […] If you have ulcerative colitis and do not take a regular preventative medicine, you have about a 5-7 in 10 chance of having at least one flare-up each year. This is reduced to about a 3 in 10 chance if you take a preventative medicine each day. […] An aminosalicylate medicine, usually mesalazine (described above), is commonly used to prevent flare-ups. […] Recent studies indicate that the risk of cancer is reduced in people who take regular long-term aminosalicylate medication (described above). In one study, people with ulcerative colitis who regularly took mesalazine had a 75% reduced risk of developing colon cancer.
  • #27 Chemoprevention of Colitis-Associated Dysplasia or Cancer in Inflammatory Bowel Disease
    https://www.gutnliver.org/journal/view.html?volume=16&number=6&spage=840
    The association between inflammatory bowel disease and colorectal cancer is well known. […] In patients with inflammatory bowel disease, control of chronic inflammation and surveillance colonoscopies are important for the prevention of colorectal cancer. […] Current evidence supports the use of chemoprevention therapy with mesalamine to reduce the risk of colorectal cancer in patients with ulcerative colitis. […] The 2017 ECCO consensus states that mesalamine compounds may decrease the incidence of CRC in UC. […] Controlled chronic inflammation and surveillance colonoscopy are important for the prevention of CRC in IBD patients. […] Current evidence supports chemoprevention with mesalamine to reduce CRC among UC patients.
  • #28 Vedolizumab for the treatment of active and inactive ulcerative colitis | Cochrane
    https://www.cochrane.org/CD007571/IBD_vedolizumab-for-the-treatment-of-active-and-inactive-ulcerative-colitis
    Evidence from one study suggests that vedolizumab is superior to placebo for preventing relapse (recurrence of active disease) in patients with ulcerative colitis in remission. […] Moderate to high quality data from four studies shows that vedolizumab is superior to placebo for induction of clinical remission and response and endoscopic remission in patients with moderate to severely active ulcerative colitis and prevention of relapse in patients with quiescent ulcerative colitis. […] Moderate quality data from one study suggests that vedolizumab is superior to placebo for prevention of relapse in patients with quiescent ulcerative colitis. […] Future trials are needed to define the optimal dose, frequency of administration and long-term efficacy and safety of vedolizumab used for induction and maintenance therapy of ulcerative colitis. […] Vedolizumab should be compared to other currently approved therapies for ulcerative colitis in these trials.
  • #29 Ulcerative colitis flare-ups: 5 tips to manage them
    https://www.mayoclinic.org/diseases-conditions/ulcerative-colitis/in-depth/ulcerative-colitis-flare-up/art-20120410
    Diet and lifestyle changes may help control ulcerative colitis symptoms and lengthen the time between flare-ups. […] Changes in your diet and lifestyle may help control your symptoms and lengthen the time between flare-ups. […] Try limiting or eliminating milk, yogurt, cheese, ice cream and other dairy products. This may help reduce symptoms of diarrhea, abdominal pain and gas. […] If you have ulcerative colitis, these foods may make your symptoms worse. […] You may feel better if you eat five or six small meals a day. […] Drink plenty of liquids every day. Water is the best choice. […] While stress doesn’t cause ulcerative colitis, it may make your symptoms worse and trigger flare-ups. Exercise may help reduce tension and keep your bowels working properly.
  • #30 Ulcerative colitis flare-ups: 5 tips to manage them
    https://www.mayoclinic.org/diseases-conditions/ulcerative-colitis/in-depth/ulcerative-colitis-flare-up/art-20120410
    Diet and lifestyle changes may help control ulcerative colitis symptoms and lengthen the time between flare-ups. […] Changes in your diet and lifestyle may help control your symptoms and lengthen the time between flare-ups. […] Try limiting or eliminating milk, yogurt, cheese, ice cream and other dairy products. This may help reduce symptoms of diarrhea, abdominal pain and gas. […] If you have ulcerative colitis, these foods may make your symptoms worse. […] You may feel better if you eat five or six small meals a day. […] Drink plenty of liquids every day. Water is the best choice. […] While stress doesn’t cause ulcerative colitis, it may make your symptoms worse and trigger flare-ups. Exercise may help reduce tension and keep your bowels working properly.
  • #31 Ulcerative Colitis | Cedars-Sinai
    https://www.cedars-sinai.org/health-library/diseases-and-conditions/u/ulcerative-colitis.html
    Experts dont know what causes ulcerative colitis. They also dont know how to prevent the disease. […] But good nutrition can play an important role in managing the disease. Changes in diet can help reduce symptoms. Some of the dietary changes that may be advised include: Not drinking carbonated drinks, Not eating high-fiber foods such as popcorn, vegetable skins, and nuts while you have symptoms, Drinking more liquids, Eating more frequent, smaller meals, Keeping a food diary that identifies foods that cause symptoms. […] In some cases, your provider may ask you to avoid taking NSAIDs, pain medicines such as ibuprofen, naproxen, or similar. This is because these medicines can cause the ulcerative colitis to flare in some people.
  • #32 Ulcerative Colitis | Cedars-Sinai
    https://www.cedars-sinai.org/health-library/diseases-and-conditions/u/ulcerative-colitis.html
    Experts dont know what causes ulcerative colitis. They also dont know how to prevent the disease. […] But good nutrition can play an important role in managing the disease. Changes in diet can help reduce symptoms. Some of the dietary changes that may be advised include: Not drinking carbonated drinks, Not eating high-fiber foods such as popcorn, vegetable skins, and nuts while you have symptoms, Drinking more liquids, Eating more frequent, smaller meals, Keeping a food diary that identifies foods that cause symptoms. […] In some cases, your provider may ask you to avoid taking NSAIDs, pain medicines such as ibuprofen, naproxen, or similar. This is because these medicines can cause the ulcerative colitis to flare in some people.
  • #33 Ulcerative Colitis
    https://healthlibrary.uwmedicine.org/Library/DiseasesConditions/Adult/Digestive/85,P00383
    Experts dont know what causes ulcerative colitis. They also dont know how to prevent the disease. […] But good nutrition can play an important role in managing the disease. Changes in diet can help reduce symptoms. Some of the dietary changes that may be advised include: Not drinking carbonated drinks […] Not eating high-fiber foods such as popcorn, vegetable skins, and nuts while you have symptoms […] Drinking more liquids […] Eating more frequent, smaller meals […] Keeping a food diary that identifies foods that cause symptoms. […] In some cases, your provider may ask you to avoid taking NSAIDs, pain medicines such as ibuprofen, naproxen, or similar. This is because these medicines can cause the ulcerative colitis to flare in some people.
  • #34 6 Natural Remedies to Help With Ulcerative Colitis
    https://www.healthline.com/health/ulcerative-colitis-take-control-natural-remedies
    A 2021 review notes that some diets for UC may also help you maintain or achieve remission, such as: Mediterranean diet, vegetarian or vegan diets, low FODMAP diet, paleo diet, low fat diet. […] Low fiber diets may be recommended for the short term if you’re experiencing a UC flare-up. It’s important to reintroduce fiber when your symptoms improve, as this may help you stay in remission and improve bowel regularity and gut health. […] Research suggests some herbal remedies may have antioxidant and anti-inflammatory properties that could help promote gut health, relieve UC symptoms, and prolong remission. […] Probiotics introduce healthy gut bacteria to help restore and maintain a natural microbial flora in the gut. This may help reduce harmful inflammatory responses caused by UC and maintain remission.
  • #35 Ulcerative Colitis: How to Prevent and Manage Flare-Ups
    https://www.webmd.com/ibd-crohns-disease/ulcerative-colitis/managing-ulcerative-colitis
    Take your UC medications exactly as prescribed. It’s one of the best things you can do to manage ulcerative colitis and prevent flares. […] You may have heard about diets for people with ulcerative colitis. There’s no evidence that certain foods can cause UC, cure it, or set off a flare. But if you’re having a flare, what you eat and drink can make symptoms worse: […] When you’re having a flare: Eat smaller meals eaten more often. It may be easier on your system. […] Talk to your doctor to see if they recommend you take supplements. You could think about seeing a nutritionist, too. They can come up with an eating plan that works for you. […] It won’t stop flare-ups from happening, but being active can improve your overall health, lift your mood, boost your immune system, and prevent some complications of the disease.
  • #36 6 Natural Remedies to Help With Ulcerative Colitis
    https://www.healthline.com/health/ulcerative-colitis-take-control-natural-remedies
    Diet plays a significant role in managing UC symptoms and maintaining remission. Eliminating common trigger foods like whole grains, nuts, legumes, seeds, lactose, gluten, raw fruits and vegetables, and processed foods may help prevent or reduce symptoms. […] Regular exercise, particularly low impact activities like walking, cycling, swimming, rowing, and yoga, can help reduce disease progression, boost immune health, and improve mood and quality of life. […] Managing stress through activities like deep breathing, meditation, physical activity, and joining support groups may help prevent UC flares, as research shows stress can trigger symptom flare-ups. […] Eliminating or reducing the following common trigger foods may help you prevent or reduce symptoms of UC: whole grains, nuts, legumes, and seeds, lactose, gluten, raw, unpeeled fruits and vegetables, cruciferous vegetables, such as broccoli and cauliflower, added sugars, ultra-processed, fried, and fatty foods, sugar-sweetened beverages, alcohol, if applicable.
  • #37 6 Natural Remedies to Help With Ulcerative Colitis
    https://www.healthline.com/health/ulcerative-colitis-take-control-natural-remedies
    Diet plays a significant role in managing UC symptoms and maintaining remission. Eliminating common trigger foods like whole grains, nuts, legumes, seeds, lactose, gluten, raw fruits and vegetables, and processed foods may help prevent or reduce symptoms. […] Regular exercise, particularly low impact activities like walking, cycling, swimming, rowing, and yoga, can help reduce disease progression, boost immune health, and improve mood and quality of life. […] Managing stress through activities like deep breathing, meditation, physical activity, and joining support groups may help prevent UC flares, as research shows stress can trigger symptom flare-ups. […] Eliminating or reducing the following common trigger foods may help you prevent or reduce symptoms of UC: whole grains, nuts, legumes, and seeds, lactose, gluten, raw, unpeeled fruits and vegetables, cruciferous vegetables, such as broccoli and cauliflower, added sugars, ultra-processed, fried, and fatty foods, sugar-sweetened beverages, alcohol, if applicable.
  • #38 Ulcerative Colitis: How to Prevent and Manage Flare-Ups
    https://www.webmd.com/ibd-crohns-disease/ulcerative-colitis/managing-ulcerative-colitis
    Stress may not bring on a flare, but it does make digestive symptoms worse. Along with exercise, some things you can do to lower your stress include: […] If you let your family and friends know what you’re going through, they can help and support you. Find a support group to talk to others who are managing UC.
  • #39 6 Natural Remedies to Help With Ulcerative Colitis
    https://www.healthline.com/health/ulcerative-colitis-take-control-natural-remedies
    A 2021 review notes that some diets for UC may also help you maintain or achieve remission, such as: Mediterranean diet, vegetarian or vegan diets, low FODMAP diet, paleo diet, low fat diet. […] Low fiber diets may be recommended for the short term if you’re experiencing a UC flare-up. It’s important to reintroduce fiber when your symptoms improve, as this may help you stay in remission and improve bowel regularity and gut health. […] Research suggests some herbal remedies may have antioxidant and anti-inflammatory properties that could help promote gut health, relieve UC symptoms, and prolong remission. […] Probiotics introduce healthy gut bacteria to help restore and maintain a natural microbial flora in the gut. This may help reduce harmful inflammatory responses caused by UC and maintain remission.
  • #40 Ulcerative Colitis Resource Center
    https://www.healio.com/news/gastroenterology/20170628/probiotics-show-some-benefits-in-ulcerative-colitis
    A new systematic review and meta-analysis of available medical literature suggested probiotics may provide some benefits to patients with ulcerative colitis, but not Crohns disease. […] In particular, probiotics may be as effective as 5-aminosalicylates for preventing relapse in quiescent UC, and the probiotic medical food VSL#3 (Ferring Pharmaceuticals) appeared effective for inducing remission in active UC. […] Moreover, the investigators found probiotics and 5-ASAs were equally effective for preventing relapse in quiescent UC (RR = 1.02, 95% CI; 0.85-1.23), based on three randomized controlled trials in which 39.7% of 277 patients who received probiotics and 39.2% of 109 patients who received 5-ASAs relapsed. […] However, the number of studies that have examined this issue is small and further high quality RCTs are required to determine their efficacy in this situation, Ford and colleagues concluded.
  • #41 6 Natural Remedies to Help With Ulcerative Colitis
    https://www.healthline.com/health/ulcerative-colitis-take-control-natural-remedies
    A 2023 review looked at the effects of probiotics for treating Crohn’s disease and UC, the two types of IBD. The authors found that only 4 out of 11 studies showed benefits of taking probiotics for Crohn’s disease. However, 21 of 25 studies showed that probiotics helped promote and maintain remission for UC. […] Consider speaking with a healthcare professional before taking probiotics. They may recommend an alternative based on your health condition. […] Managing a chronic condition like UC can feel stressful, and research from 2019 shows that stress may trigger a UC flare. […] You can experiment with various stress-relief strategies to determine which ones work best for you. […] Acupuncture may help improve UC symptoms and disease biomarkers when used alone or in combination with other treatments, such as medication. […] It’s advisable to speak with a healthcare professional if your symptoms frequently flare up. They can help adjust your treatment plan.
  • #42 Ulcerative Colitis Resource Center
    https://www.healio.com/news/gastroenterology/20170628/probiotics-show-some-benefits-in-ulcerative-colitis
    A new systematic review and meta-analysis of available medical literature suggested probiotics may provide some benefits to patients with ulcerative colitis, but not Crohns disease. […] In particular, probiotics may be as effective as 5-aminosalicylates for preventing relapse in quiescent UC, and the probiotic medical food VSL#3 (Ferring Pharmaceuticals) appeared effective for inducing remission in active UC. […] Moreover, the investigators found probiotics and 5-ASAs were equally effective for preventing relapse in quiescent UC (RR = 1.02, 95% CI; 0.85-1.23), based on three randomized controlled trials in which 39.7% of 277 patients who received probiotics and 39.2% of 109 patients who received 5-ASAs relapsed. […] However, the number of studies that have examined this issue is small and further high quality RCTs are required to determine their efficacy in this situation, Ford and colleagues concluded.
  • #43 Ulcerative Colitis Resource Center
    https://www.healio.com/news/gastroenterology/20170628/probiotics-show-some-benefits-in-ulcerative-colitis
    A new systematic review and meta-analysis of available medical literature suggested probiotics may provide some benefits to patients with ulcerative colitis, but not Crohns disease. […] In particular, probiotics may be as effective as 5-aminosalicylates for preventing relapse in quiescent UC, and the probiotic medical food VSL#3 (Ferring Pharmaceuticals) appeared effective for inducing remission in active UC. […] Moreover, the investigators found probiotics and 5-ASAs were equally effective for preventing relapse in quiescent UC (RR = 1.02, 95% CI; 0.85-1.23), based on three randomized controlled trials in which 39.7% of 277 patients who received probiotics and 39.2% of 109 patients who received 5-ASAs relapsed. […] However, the number of studies that have examined this issue is small and further high quality RCTs are required to determine their efficacy in this situation, Ford and colleagues concluded.
  • #44 The use of pharmacological prophylaxis against venous thromboembolism in hospitalised patients with severe active ulcerative colitis
    https://pmc.ncbi.nlm.nih.gov/articles/PMC5552167/
    Hospitalised patients with inflammatory bowel disease are 1.5- to 3.5-fold more likely to develop venous thromboembolism compared to controls. Clinical guidelines recommend pharmacological prophylaxis. […] Hospitalised patients admitted with severe active ulcerative colitis are not receiving appropriate pharmacological venous thromboembolism prophylaxis. […] Despite the recommendation that patients admitted to the hospital with ulcerative colitis flare should be given pharmacological venous thrombosis prophylaxis, our study found that most patients are not receiving adequate prophylaxis. This was due both to under-prescribing by physicians and inconsistent administration by the nursing staff. Given the high incidence of VTE demonstrated in this patient population, adequate prophylaxis is imperative. Quality improvement efforts focusing on physician and nursing education regarding the risk of VTE and the safety of VTE prophylaxis are needed to improve compliance.
  • #45 International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease | Nature Reviews Gastroenterology & Hepatology
    https://www.nature.com/articles/s41575-021-00492-8
    Patients with IBD harbour an increased risk of venous and arterial thrombotic events. […] Thromboprophylaxis is indicated during hospitalization of any cause in patients with IBD. […] Disease activity is a modifiable risk factor in patients with IBD, and physicians should aim to achieve deep remission to reduce the risk. […] Exposure to steroids should be limited. […] Antitumour necrosis factor agents might be associated with a reduced risk of thrombotic events. […] Thromboprophylaxis should be given to patients with IBD during hospitalization of any cause. Low molecular weight heparin or fondaparinux is recommended over low-dose unfractionated heparin. […] Thromboprophylaxis should be considered in ambulatory patients with active IBD with known risk factors for VTE and maintained until the patient is in remission.
  • #46 International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease | Nature Reviews Gastroenterology & Hepatology
    https://www.nature.com/articles/s41575-021-00492-8
    Patients with IBD harbour an increased risk of venous and arterial thrombotic events. […] Thromboprophylaxis is indicated during hospitalization of any cause in patients with IBD. […] Disease activity is a modifiable risk factor in patients with IBD, and physicians should aim to achieve deep remission to reduce the risk. […] Exposure to steroids should be limited. […] Antitumour necrosis factor agents might be associated with a reduced risk of thrombotic events. […] Thromboprophylaxis should be given to patients with IBD during hospitalization of any cause. Low molecular weight heparin or fondaparinux is recommended over low-dose unfractionated heparin. […] Thromboprophylaxis should be considered in ambulatory patients with active IBD with known risk factors for VTE and maintained until the patient is in remission.
  • #47 International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease | Nature Reviews Gastroenterology & Hepatology
    https://www.nature.com/articles/s41575-021-00492-8
    Thromboprophylaxis does not increase the risk of further IBD-related gastrointestinal bleeding in patients with active disease. […] Control of disease activity is an important factor in reducing the risk of venous and arterial thrombotic events in patients with IBD. […] Established cardiovascular disease risk factors should be actively investigated and controlled in patients with IBD.
  • #48 Ulcerative Colitis – Harvard Health
    https://www.health.harvard.edu/a_to_z/ulcerative-colitis-a-to-z
    There is no way to prevent ulcerative colitis. […] However, some people are able to decrease the frequency of symptoms. They do this by avoiding foods that seem to provoke flare-ups. For some people with ulcerative colitis, this includes spicy foods and milk products. […] If you have ulcerative colitis, you can decrease the toll it takes on your body. To do this, eat a well-balanced, nutritious diet especially when you are not having symptoms such as poor appetite and nausea that make it hard to eat. By doing so, you can decrease complications from malnutrition, such as weight loss or a low blood count. […] Ulcerative colitis increases your risk of colon cancer. People with extensive inflammation in the whole colon have the highest risk. It is important to have your colon checked frequently for early signs of cancer. Ask your doctor how often you should have a colonoscopy. […] Poor nutrition or the effect of colitis medicines can lead to osteoporosis. This disease weakens bones and can cause bones to break. Osteoporosis can be prevented with medicines, adequate exercise, calcium, and vitamin D. If you have ulcerative colitis, discuss osteoporosis with your doctor.
  • #49 Ulcerative Colitis: Diagnosis and Treatment | AAFP
    https://www.aafp.org/pubs/afp/issues/2007/1101/p1323.html
    Patients who take chronic steroids for their ulcerative colitis should be screened for osteoporosis, and they usually receive prophylactic therapy with calcium, vitamin D, and bisphosphonates. […] Patients with ulcerative colitis can receive nonpathogenic Escherichia coli instead of 5-ASA to prevent disease relapse. […] The American College of Rheumatology published guidelines on the prevention and treatment of glucocorticoid-induced osteoporosis. All patients on chronic steroid therapy should be counseled to participate in regular weight-bearing exercise; screened for osteoporosis with dual energy x-ray absorptiometry; and considered for prophylaxis with calcium, vitamin D, and bisphosphonates. […] A meta-analysis of nine observational studies involving more than 1,900 patients found an association between 5-ASA use and a decreased likelihood of colorectal cancer.
  • #50 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro
    https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/
    Finally, weight bearing exercise and calcium/ vitamin D supplementation, when appropriate, can prevent downstream osteoporotic fracture in these patients who may require recurrent courses of corticosteroids during their lifetimes with IBD. […] Secondary prevention is defined as detecting a disease early to prevent disability; such as through screening programs. […] Therefore, there are a number of important opportunities for secondary prevention in IBD patients. […] Therefore, a dermatology skin screening program is recommended in all patients with IBD. […] Annual cervical cancer screening is recommended in patients with IBD on immunosuppression. […] Therefore, patients with longstanding colonic inflammation should undergo routine colonoscopy starting at 8-10 years of colonic disease duration, with subsequent colonoscopy intervals based on the results (often every 1-3 years).
  • #51 Ulcerative Colitis: Rapid Evidence Review | AAFP
    https://www.aafp.org/pubs/afp/issues/2022/0400/p406.html
    Vaccinations should be given according to routine recommendations from the Advisory Committee on Immunization Practices and the Centers for Disease Control and Prevention, paying special attention to additional vaccinations necessary for patients on immunosuppressive therapies. […] Dual energy x-ray absorptiometry is recommended to check for low bone mineral density in patients with ulcerative colitis, especially those with a history of chronic oral corticosteroid use for three months or more. […] Skin cancer occurs at higher rates in patients with inflammatory bowel disease. In addition, common therapies for ulcerative colitis increase the risk of melanoma and nonmelanoma skin cancer. […] The American College of Obstetricians and Gynecologists recommends annual cytology screening for cervical cancer in women on immunosuppressive therapy.
  • #52 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro
    https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/
    Finally, weight bearing exercise and calcium/ vitamin D supplementation, when appropriate, can prevent downstream osteoporotic fracture in these patients who may require recurrent courses of corticosteroids during their lifetimes with IBD. […] Secondary prevention is defined as detecting a disease early to prevent disability; such as through screening programs. […] Therefore, there are a number of important opportunities for secondary prevention in IBD patients. […] Therefore, a dermatology skin screening program is recommended in all patients with IBD. […] Annual cervical cancer screening is recommended in patients with IBD on immunosuppression. […] Therefore, patients with longstanding colonic inflammation should undergo routine colonoscopy starting at 8-10 years of colonic disease duration, with subsequent colonoscopy intervals based on the results (often every 1-3 years).
  • #53 Ulcerative Colitis Treatment | Medication and Surgery – UChicago Medicine
    https://www.uchicagomedicine.org/conditions-services/inflammatory-bowel-disease/ulcerative-colitis
    Ulcerative colitis is a condition that affects the large intestine. […] We don’t know the cause of ulcerative colitis, but we do know a lot about how to treat it. […] When people have ulcerative colitis and it’s long standing, meaning more than 8 or 10 or 20 years, there is a slightly increased risk for them to develop pre-cancerous changes of the bowel. […] Fortunately, we think that this is on the decline, in part due to effective medicines, but also in part due to a prevention strategy we have, where we do colonoscopies after you’ve had disease for eight years or so, and we look for pre-cancerous changes. […] Another important component of understanding this is that the risk of developing pre-cancerous changes is directly related to how much inflammation there’s been in the bowel over time. […] It really behooves us to get your disease under control, and for patients to be taking their therapy, and to stay well. […] Correctly diagnosing, treating and preventing ulcerative colitis is very important to reducing the risk of these complications later on.
  • #54 Chemoprevention of Colitis-Associated Dysplasia or Cancer in Inflammatory Bowel Disease
    https://www.gutnliver.org/journal/view.html?volume=16&number=6&spage=840
    The association between inflammatory bowel disease and colorectal cancer is well known. […] In patients with inflammatory bowel disease, control of chronic inflammation and surveillance colonoscopies are important for the prevention of colorectal cancer. […] Current evidence supports the use of chemoprevention therapy with mesalamine to reduce the risk of colorectal cancer in patients with ulcerative colitis. […] The 2017 ECCO consensus states that mesalamine compounds may decrease the incidence of CRC in UC. […] Controlled chronic inflammation and surveillance colonoscopy are important for the prevention of CRC in IBD patients. […] Current evidence supports chemoprevention with mesalamine to reduce CRC among UC patients.
  • #55 Ulcerative Colitis: Diagnosis and Treatment | AAFP
    https://www.aafp.org/pubs/afp/issues/2007/1101/p1323.html
    Patients who take chronic steroids for their ulcerative colitis should be screened for osteoporosis, and they usually receive prophylactic therapy with calcium, vitamin D, and bisphosphonates. […] Patients with ulcerative colitis can receive nonpathogenic Escherichia coli instead of 5-ASA to prevent disease relapse. […] The American College of Rheumatology published guidelines on the prevention and treatment of glucocorticoid-induced osteoporosis. All patients on chronic steroid therapy should be counseled to participate in regular weight-bearing exercise; screened for osteoporosis with dual energy x-ray absorptiometry; and considered for prophylaxis with calcium, vitamin D, and bisphosphonates. […] A meta-analysis of nine observational studies involving more than 1,900 patients found an association between 5-ASA use and a decreased likelihood of colorectal cancer.
  • #56 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro
    https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/
    Patients with inflammatory bowel disease (IBD) are subject to complications from the disease itself and also from the immunosuppressive therapies used for treatment. […] To optimize the care of patients with IBD, providers need to consider primary, secondary and tertiary prevention. […] Primary prevention is defined as prevention of disease development. […] As compared to the age-matched general population, patients with IBD are at increased risk for vaccine-preventable illnesses, such as influenza, pneumococcal pneumonia, and shingles. […] Therefore, adherence to vaccination guidelines of inactivated vaccines can reduce these infectious complications. […] Another method of primary prevention in IBD patients is sunscreen use to prevent skin cancer. […] Therefore, this is a potentially preventable complication of therapy through broad-spectrum sunscreen use.
  • #57 Ulcerative Colitis: Rapid Evidence Review | AAFP
    https://www.aafp.org/pubs/afp/issues/2022/0400/p406.html
    Vaccinations should be given according to routine recommendations from the Advisory Committee on Immunization Practices and the Centers for Disease Control and Prevention, paying special attention to additional vaccinations necessary for patients on immunosuppressive therapies. […] Dual energy x-ray absorptiometry is recommended to check for low bone mineral density in patients with ulcerative colitis, especially those with a history of chronic oral corticosteroid use for three months or more. […] Skin cancer occurs at higher rates in patients with inflammatory bowel disease. In addition, common therapies for ulcerative colitis increase the risk of melanoma and nonmelanoma skin cancer. […] The American College of Obstetricians and Gynecologists recommends annual cytology screening for cervical cancer in women on immunosuppressive therapy.
  • #58 Ulcerative Colitis: Rapid Evidence Review | AAFP
    https://www.aafp.org/pubs/afp/issues/2022/0400/p406.html
    Vaccinations should be given according to routine recommendations from the Advisory Committee on Immunization Practices and the Centers for Disease Control and Prevention, paying special attention to additional vaccinations necessary for patients on immunosuppressive therapies. […] Dual energy x-ray absorptiometry is recommended to check for low bone mineral density in patients with ulcerative colitis, especially those with a history of chronic oral corticosteroid use for three months or more. […] Skin cancer occurs at higher rates in patients with inflammatory bowel disease. In addition, common therapies for ulcerative colitis increase the risk of melanoma and nonmelanoma skin cancer. […] The American College of Obstetricians and Gynecologists recommends annual cytology screening for cervical cancer in women on immunosuppressive therapy.
  • #59 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro
    https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/
    Patients with inflammatory bowel disease (IBD) are subject to complications from the disease itself and also from the immunosuppressive therapies used for treatment. […] To optimize the care of patients with IBD, providers need to consider primary, secondary and tertiary prevention. […] Primary prevention is defined as prevention of disease development. […] As compared to the age-matched general population, patients with IBD are at increased risk for vaccine-preventable illnesses, such as influenza, pneumococcal pneumonia, and shingles. […] Therefore, adherence to vaccination guidelines of inactivated vaccines can reduce these infectious complications. […] Another method of primary prevention in IBD patients is sunscreen use to prevent skin cancer. […] Therefore, this is a potentially preventable complication of therapy through broad-spectrum sunscreen use.
  • #60 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro
    https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/
    Patients with inflammatory bowel disease (IBD) are subject to complications from the disease itself and also from the immunosuppressive therapies used for treatment. […] To optimize the care of patients with IBD, providers need to consider primary, secondary and tertiary prevention. […] Primary prevention is defined as prevention of disease development. […] As compared to the age-matched general population, patients with IBD are at increased risk for vaccine-preventable illnesses, such as influenza, pneumococcal pneumonia, and shingles. […] Therefore, adherence to vaccination guidelines of inactivated vaccines can reduce these infectious complications. […] Another method of primary prevention in IBD patients is sunscreen use to prevent skin cancer. […] Therefore, this is a potentially preventable complication of therapy through broad-spectrum sunscreen use.
  • #61 Ulcerative Colitis: Rapid Evidence Review | AAFP
    https://www.aafp.org/pubs/afp/issues/2022/0400/p406.html
    Vaccinations should be given according to routine recommendations from the Advisory Committee on Immunization Practices and the Centers for Disease Control and Prevention, paying special attention to additional vaccinations necessary for patients on immunosuppressive therapies. […] Dual energy x-ray absorptiometry is recommended to check for low bone mineral density in patients with ulcerative colitis, especially those with a history of chronic oral corticosteroid use for three months or more. […] Skin cancer occurs at higher rates in patients with inflammatory bowel disease. In addition, common therapies for ulcerative colitis increase the risk of melanoma and nonmelanoma skin cancer. […] The American College of Obstetricians and Gynecologists recommends annual cytology screening for cervical cancer in women on immunosuppressive therapy.
  • #62 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro
    https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/
    Patients with inflammatory bowel disease (IBD) are subject to complications from the disease itself and also from the immunosuppressive therapies used for treatment. […] To optimize the care of patients with IBD, providers need to consider primary, secondary and tertiary prevention. […] Primary prevention is defined as prevention of disease development. […] As compared to the age-matched general population, patients with IBD are at increased risk for vaccine-preventable illnesses, such as influenza, pneumococcal pneumonia, and shingles. […] Therefore, adherence to vaccination guidelines of inactivated vaccines can reduce these infectious complications. […] Another method of primary prevention in IBD patients is sunscreen use to prevent skin cancer. […] Therefore, this is a potentially preventable complication of therapy through broad-spectrum sunscreen use.
  • #63
    https://link.springer.com/article/10.1007/s13659-024-00463-x
    Ulcerative colitis (UC) is a recurring autoimmune disorder characterized by persistent inflammation in the mucosal lining of the lower part of the large intestine. […] Therefore, it is imperative to explore natural strategies as safe and alternative treatments for UC. Currently, around 40% of UC patients find relief through natural constituents, which can help reduce toxic side effects and maintain clinical remission. […] This review aims to provide a summary of both preclinical and clinical evidence supporting the efficacy of various natural substances in the prophylaxis of UC. […] In recent decades, numerous investigations demonstrated the protective, medicinal, preventive, and mitigating effects of natural compounds on colonic inflammation. […] These natural compounds often possess oxido-inflammatory and immunomodulatory activities, rendering them potential candidates for the treatment of UC.
  • #64
    https://link.springer.com/article/10.1007/s13659-024-00463-x
    Therefore, in this article, we have provided an insight into the importance of natural or herbal substances; including plant extracts essential oils, nutraceuticals, and phytochemicals, along with the underlying mechanisms that contribute to their efficacy in preventing or treating UC. […] Novel herbal approaches for UC are gaining huge attention as complementary or alternative therapies to conventional medications. […] While further research is necessary to establish their safety and effectiveness, these herbal approaches offer a promising avenue for individuals seeking alternative or adjunctive treatments for UC. […] The treatment of UC involves the modulation of various immunoinflammatory pathways, including the activation and suppression of key mechanisms such as PPAR, Nrf2, NF-kB, and macrophages, along with the regulation of the Th17/Treg balance.
  • #65 Curcumin, an active component of turmeric in the prevention and treatment of ulcerative colitis: preclinical and clinical observations – Food & Function (RSC Publishing)
    https://pubs.rsc.org/en/content/articlelanding/2012/fo/c2fo30097d
    Curcumin, an active principle of the Indian spice turmeric (Curcuma longa) is effective in preventing or ameliorating UC and inflammation. […] Clinical studies have also shown that co-administration of curcumin with conventional drugs was effective, to be well-tolerated and treated as a safe medication for maintaining remission, to prevent relapse and improve clinical activity index. […] Large randomized controlled clinical investigations are required to fully understand the potential of oral curcumin for treating IBD.
  • #66 Virgin Coconut Oil Supplementation as Ulcerative Colitis Prevention, Does it work? Clinical Correlation
    https://www.jmchemsci.com/article_177819.html
    Ulcerative colitis (UC) is an inflammatory disease of the large intestine characterized by diffuse mucosal damage accompanied by ulceration. […] One of them, virgin coconut oil (VCO), is thought to be used as UC therapy. […] To see the VCO supplementation effect as a prevention of Ulcerative Colitis by measuring inflammatory cytokine levels, Mouse Colitis Histopathology Index (MCHI) scores, and Disease Activity Index (DAI) scores. […] VCO supplementation can be used to prevent ulcerative colitis by increasing IL-10 levels while reducing IL-6, TNF-, DAI, and MCHI scores. […] These effects can be caused by compounds in VCO with potential as anti-inflammatories and antioxidants. […] The study results are expected to provide a scientific basis for administering VCO to colitis in general to achieve a safe and efficient UC prevention composition with effective results, minimal complications, and relatively economical costs.
  • #67 Double blind placebo-controlled trial for the prevention of ulcerative colitis relapses by β-fructan prebiotics: efficacy and metabolomic analysis | medRxiv
    https://www.medrxiv.org/content/10.1101/2022.01.16.22269376.full
    Although oligofructose and inulin did not prevent symptomatic relapses in UC patients, their oral administration significantly reduced the severity of biochemical relapse compared to placebo which was further associated with increased anti-inflammatory metabolites. […] This RCT study suggest that intake of 15 g/day -fructans over a 6-month period could induce significant reduction in FCP and subclinical remission. These findings suggest that high-dose inulin-type fructan fibre supplement improves subclinical colitis demonstrating their promising potential as an adjunct treatment to aid in maintaining remission in UC.
  • #68
    https://link.springer.com/article/10.1007/s13659-024-00463-x
    Therefore, in this article, we have provided an insight into the importance of natural or herbal substances; including plant extracts essential oils, nutraceuticals, and phytochemicals, along with the underlying mechanisms that contribute to their efficacy in preventing or treating UC. […] Novel herbal approaches for UC are gaining huge attention as complementary or alternative therapies to conventional medications. […] While further research is necessary to establish their safety and effectiveness, these herbal approaches offer a promising avenue for individuals seeking alternative or adjunctive treatments for UC. […] The treatment of UC involves the modulation of various immunoinflammatory pathways, including the activation and suppression of key mechanisms such as PPAR, Nrf2, NF-kB, and macrophages, along with the regulation of the Th17/Treg balance.
  • #69 Ulcerative Colitis – prevention and treatment with a plant-based diet – Plant-Based Diets in Medicine
    https://pbdmedicine.org/ulcerative-colitis-prevention-and-treatment-with-a-plant-based-diet/
    Ulcerative colitis Prevention and Treatment with a Plant-Based […] Therefore, practicing prevention with this disease is particularly desirable. […] A plant-based diet can significantly reduce the risk or relapse in ulcerative colitis patients, almost as effectively as the leading drug, Mesalamine. […] Treating the ulcerative colitis patient with a plant-based diet has no contraindications or adverse reactions, is affordable and can prevent and treat common comorbidities such as type 2 diabetes and coronary artery disease. […] If ulcerative colitis is accepted to be a lifestyle disease mainly caused, or exacerbated by a westernized diet, then current practice should move toward encouraging the patient to change their diet. A plant-based diet is naturally much higher in fiber than the average American diet, thus promoting the bacterial species in the gut that produce butyrate, resulting in lower inflammation.
  • #70 Ulcerative Colitis – prevention and treatment with a plant-based diet – Plant-Based Diets in Medicine
    https://pbdmedicine.org/ulcerative-colitis-prevention-and-treatment-with-a-plant-based-diet/
    A plant-based diet can significantly reduce the risk or relapse in ulcerative colitis patients, almost as effectively as the leading drug, Mesalamine. It can be used as a monotherapy or as an adjunct along with medications that are usually prescribed for ulcerative colitis patients. […] Treating the ulcerative colitis patient with a plant-based diet has several advantages. It has no contraindications or adverse reactions, is affordable and can prevent and treat common comorbidities such as type 2 diabetes and coronary artery disease. It also reduces the risk of colon cancer, which is raised for long standing cases of ulcerative colitis patients. […] Given all of the benefits, the plant-based diet deserves a place among the physicians treatment options for ulcerative colitis.
  • #71 Ulcerative Colitis – prevention and treatment with a plant-based diet – Plant-Based Diets in Medicine
    https://pbdmedicine.org/ulcerative-colitis-prevention-and-treatment-with-a-plant-based-diet/
    A plant-based diet can significantly reduce the risk or relapse in ulcerative colitis patients, almost as effectively as the leading drug, Mesalamine. It can be used as a monotherapy or as an adjunct along with medications that are usually prescribed for ulcerative colitis patients. […] Treating the ulcerative colitis patient with a plant-based diet has several advantages. It has no contraindications or adverse reactions, is affordable and can prevent and treat common comorbidities such as type 2 diabetes and coronary artery disease. It also reduces the risk of colon cancer, which is raised for long standing cases of ulcerative colitis patients. […] Given all of the benefits, the plant-based diet deserves a place among the physicians treatment options for ulcerative colitis.
  • #72 Ulcerative Colitis – prevention and treatment with a plant-based diet – Plant-Based Diets in Medicine
    https://pbdmedicine.org/ulcerative-colitis-prevention-and-treatment-with-a-plant-based-diet/
    A plant-based diet can significantly reduce the risk or relapse in ulcerative colitis patients, almost as effectively as the leading drug, Mesalamine. It can be used as a monotherapy or as an adjunct along with medications that are usually prescribed for ulcerative colitis patients. […] Treating the ulcerative colitis patient with a plant-based diet has several advantages. It has no contraindications or adverse reactions, is affordable and can prevent and treat common comorbidities such as type 2 diabetes and coronary artery disease. It also reduces the risk of colon cancer, which is raised for long standing cases of ulcerative colitis patients. […] Given all of the benefits, the plant-based diet deserves a place among the physicians treatment options for ulcerative colitis.
  • #73 Preventive health measures in inflammatory bowel disease
    https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/
    We aim to review the literature and provide guidance on preventive health measures in inflammatory bowel disease (IBD). […] Preventive health measures can avert morbidity and improve the quality of life of patients with IBD. Gastroenterologists and primary care physicians (PCPs) should have an up to date working knowledge of preventive health measures for IBD patients. A holistic approach and better communication between gastroenterologists and PCPs with explicit clarification of roles will prevent duplication of services and streamline care. […] Effective preventive measures to reduce morbidity, hospitalization, and surgery are critical to improving disease free remission and quality of life. […] Therefore, gastroenterologists need to take a proactive role in the preventive health care needs of IBD patients by clarifying with each patient the limits of responsibility for preventive health and alerting PCPs to the unique health maintenance needs of IBD patients.
  • #74 Preventive health measures in inflammatory bowel disease
    https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/
    This article reviews health interventions to prevent morbidity and mortality in IBD patients with emphasis on the location where such interventions are best delivered. […] Preventive health care can avert morbidity, mortality, and reduce overall health care costs. […] A recent study showed that incorporating a standard curriculum on IBD health maintenance provided fellows in training with increased awareness and guidance on managing the unique preventive care needs of patients with IBD. […] The CCFA and AGA have publicized quality measures based on the best available evidence for processes and outcomes related to high quality care of IBD patients.
  • #75 Preventive health measures in inflammatory bowel disease
    https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/
    We aim to review the literature and provide guidance on preventive health measures in inflammatory bowel disease (IBD). […] Preventive health measures can avert morbidity and improve the quality of life of patients with IBD. Gastroenterologists and primary care physicians (PCPs) should have an up to date working knowledge of preventive health measures for IBD patients. A holistic approach and better communication between gastroenterologists and PCPs with explicit clarification of roles will prevent duplication of services and streamline care. […] Effective preventive measures to reduce morbidity, hospitalization, and surgery are critical to improving disease free remission and quality of life. […] Therefore, gastroenterologists need to take a proactive role in the preventive health care needs of IBD patients by clarifying with each patient the limits of responsibility for preventive health and alerting PCPs to the unique health maintenance needs of IBD patients.
  • #76 8 Ways To Prevent or Stop an Ulcerative Colitis Flare (VIDEO) | MyCrohnsAndColitisTeam
    https://www.mycrohnsandcolitisteam.com/resources/managing-ulcerative-colitis-flare-ups
    Dr. Kinnucan emphasized the importance of regularly monitoring UC progression to catch issues early and prevent flare-ups. […] Regular checkups (at least once a year) are crucial for identifying inflammation, predicting flare-ups, and preventing complications associated with ulcerative colitis, Dr. Kinnucan noted. […] Its important to maintain your treatment plan and not make changes without medical advice. But some people feel better when theyre also taking fish oil, probiotics, or herbal supplements. […] Talk to your doctor before trying any alternative treatments, and ask about potential risks or benefits. Some dietary supplements may interact poorly with medications.
  • #77 Ulcerative colitis (UC) clinical guidance toolkitAGA Logo_Horizontal
    https://gastro.org/clinical-guidance/guideline-toolkits/ulcerative-colitis-toolkit/
    AGA suggests against using antibiotics for the primary prevention of pouchitis. […] AGA suggests a monitoring strategy that combines biomarkers and symptoms, rather than relying on symptoms alone. […] AGA provides clinical practice updates that present state-of-the-art guidance and include a combination of evidence-based information, and when not available, best consensus opinion to help clinicians manage care of people with ulcerative colitis. […] AGA University helps physicians learn about how to care for people with ulcerative colitis – including understanding disease progression and how to treat ulcerative colitis.
  • #78 Young people with ulcerative colitis at risk due to low adherence to prescribed medication – NIHR Imperial Biomedical Research Centre
    https://imperialbrc.nihr.ac.uk/2023/09/18/young-people-with-ulcerative-colitis-at-risk-due-to-low-adherence-to-prescribed-medication/
    Nearly 70 per cent of adolescents and young adults with ulcerative colitis stop taking medication to treat the disease within a year of diagnosis. […] Failure to take medication to treat the disease can result in frequent relapses, severe disease and a higher risk of colon cancer. […] The researchers say the results show that the first year of starting lifelong therapies amongst individuals diagnosed with ulcerative colitis is a critical window to improve adherence for adolescents transitioning to young adulthood and those from deprived postcodes. […] They suggest that these patients should be actively followed up by GPs to see if they are taking their medications and if they can afford them, as well as discuss with them what to do if symptoms stop and start. […] There are therapies that can put the condition into remission if taken as prescribed.
  • #79 Young people with ulcerative colitis at risk due to low adherence to prescribed medication – NIHR Imperial Biomedical Research Centre
    https://imperialbrc.nihr.ac.uk/2023/09/18/young-people-with-ulcerative-colitis-at-risk-due-to-low-adherence-to-prescribed-medication/
    However, our study shows that many adolescents and young adults are stopping their medication within a year of being diagnosed. […] This is concerning as they are at risk of their condition returning and further complications. […] As doctors, this study shows we need to be keeping a close eye on patients, particularly within the first year of starting medication. […] We should check if these patients are getting their medications and whether they have difficulty paying for them. […] International guidelines recommend that 5-ASA treatment should start promptly after diagnosis and continue long-term to maintain remission. […] The researchers suggest the higher risk of treatment discontinuation and poor adherence during the transition from adolescence to adulthood may be explained by the loss of support from caregivers who encourage adherence in adolescents and provide financial and practical support. […] The researchers suggest that monthly prescription costs may be a factor in low adherence in more deprived postcodes.
  • #80 Ulcerative Colitis: Symptoms, Causes, Diagnosis & Treatment
    https://my.clevelandclinic.org/health/diseases/10351-ulcerative-colitis
    You can reduce your likelihood of a flare-up by identifying and avoiding your triggers. Tips for avoiding common triggers include: […] Its a good idea to note your triggers in a diary you can share with your provider. Together, you can work on strategies to avoid things that may cause a flare-up.
  • #81
    https://www.parsleyhealth.com/blog/manage-ulcerative-colitis-flare-up/
    At a minimum, you want to be having three servings of vegetables per day, since low vegetable intake is associated with a higher incidence of UC, says Cohen. […] Your veggie-heavy, anti-inflammatory diet will help. But these nutrients (which you can get via food or supplements) may provide an extra boost for gut health: Probiotics, naturally found in fermented foods, are a good maintenance tool for promoting gut microbial balance. […] Keeping up a food and symptom journal can be really helpful. […] Parsley Health doctors and providers can guide you through the appropriate way to eliminate and reintroduce foods and help you identify triggers. […] But managing ulcerative colitis and preventing (or at least delaying) flare-ups can be done! You just might need a little help from the experts. […] Because UC isn’t one-size-fits-all and triggers are highly individual, enlisting the help of a care team, like the clinicians at Parsley Health, is wise.
  • #82
    https://www.parsleyhealth.com/blog/manage-ulcerative-colitis-flare-up/
    At a minimum, you want to be having three servings of vegetables per day, since low vegetable intake is associated with a higher incidence of UC, says Cohen. […] Your veggie-heavy, anti-inflammatory diet will help. But these nutrients (which you can get via food or supplements) may provide an extra boost for gut health: Probiotics, naturally found in fermented foods, are a good maintenance tool for promoting gut microbial balance. […] Keeping up a food and symptom journal can be really helpful. […] Parsley Health doctors and providers can guide you through the appropriate way to eliminate and reintroduce foods and help you identify triggers. […] But managing ulcerative colitis and preventing (or at least delaying) flare-ups can be done! You just might need a little help from the experts. […] Because UC isn’t one-size-fits-all and triggers are highly individual, enlisting the help of a care team, like the clinicians at Parsley Health, is wise.
  • #83
    https://www.prevention.com/health/health-conditions/a35783736/ulcerative-colitis-mistakes/
    It’s so important to remind yourself that even if you’re on the right medication, your disease can be active again despite doing all the right things, she says. […] Rather than spinning about what you could’ve done differently, focus on what you can do, says Dr. Devarajan: Call your doctor so you can have a conversation about why you might be experiencing symptoms again. […] If it happens to you, you’re not alone and berating yourself for something that’s very likely out of your control won’t help, adds Dr. Devarajan. […] While it may be just fine (and possibly even beneficial!), Dr. Hagan says it’s important to run it by your doctor first. […] That said, it’s still a good idea to clue your doctor into any big changes in your go-to diet. […] Think of it as a great opportunity for you and your doctor to touch base and make sure your lifestyle choices are supporting your treatment plan.
  • #84 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro
    https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/
    Therefore, screening with DEXA scan for these individuals and in women age 65 years is recommended. […] Tertiary prevention refers to utilization of measures to reduce the impact of long-term disease and disability. […] Therefore, by intervening early and treating inflammation, with a goal of mucosal healing, we can potentially prevent these morbid and potentially life-threatening, complications of IBD. […] Therefore, by optimizing therapies to improve mucosal healing, we may be able to impact the long-term disability associated with irreversible bowel damage in IBD. […] Through this partnership, an individualized plan for preventive medicine can be developed for each patient with IBD. […] By focusing on implementing the three forms of prevention: primary, secondary, and tertiary, we can improve the lives of our patients with IBD.
  • #85 Preventive health measures in inflammatory bowel disease
    https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/
    This article reviews health interventions to prevent morbidity and mortality in IBD patients with emphasis on the location where such interventions are best delivered. […] Preventive health care can avert morbidity, mortality, and reduce overall health care costs. […] A recent study showed that incorporating a standard curriculum on IBD health maintenance provided fellows in training with increased awareness and guidance on managing the unique preventive care needs of patients with IBD. […] The CCFA and AGA have publicized quality measures based on the best available evidence for processes and outcomes related to high quality care of IBD patients.
  • #86 Prevention in Inflammatory Bowel Disease: An Updated Review – Practical Gastro
    https://practicalgastro.com/2020/03/13/prevention-in-inflammatory-bowel-disease-an-updated-review/
    Therefore, screening with DEXA scan for these individuals and in women age 65 years is recommended. […] Tertiary prevention refers to utilization of measures to reduce the impact of long-term disease and disability. […] Therefore, by intervening early and treating inflammation, with a goal of mucosal healing, we can potentially prevent these morbid and potentially life-threatening, complications of IBD. […] Therefore, by optimizing therapies to improve mucosal healing, we may be able to impact the long-term disability associated with irreversible bowel damage in IBD. […] Through this partnership, an individualized plan for preventive medicine can be developed for each patient with IBD. […] By focusing on implementing the three forms of prevention: primary, secondary, and tertiary, we can improve the lives of our patients with IBD.
  • #87 Ready for This Moment: Exploring Prevention of Ulcerative Colitis | Benaroya Research Institute
    https://www.benaroyaresearch.org/blog/ready-moment-exploring-prevention-ulcerative-colitis
    Ready for This Moment: Exploring Prevention of Ulcerative Colitis […] An existing treatment for people who already have UC may also work to prevent it, Dr. Lord says. […] This could make preventing UC a reality in the near future.
  • #88 Preventive health measures in inflammatory bowel disease
    https://pmc.ncbi.nlm.nih.gov/articles/PMC5016364/
    We aim to review the literature and provide guidance on preventive health measures in inflammatory bowel disease (IBD). […] Preventive health measures can avert morbidity and improve the quality of life of patients with IBD. Gastroenterologists and primary care physicians (PCPs) should have an up to date working knowledge of preventive health measures for IBD patients. A holistic approach and better communication between gastroenterologists and PCPs with explicit clarification of roles will prevent duplication of services and streamline care. […] Effective preventive measures to reduce morbidity, hospitalization, and surgery are critical to improving disease free remission and quality of life. […] Therefore, gastroenterologists need to take a proactive role in the preventive health care needs of IBD patients by clarifying with each patient the limits of responsibility for preventive health and alerting PCPs to the unique health maintenance needs of IBD patients.