Rak skóry
Epidemiologia
Rak skóry jest najczęstszym nowotworem w populacjach o jasnej karnacji, z roczną zachorowalnością w USA sięgającą około 3,6 mln przypadków raka podstawnokomórkowego (BCC) oraz 1,8 mln raka kolczystokomórkowego (SCC), a także 212 200 nowych przypadków czerniaka, z czego 104 960 to przypadki inwazyjne. Czerniak, mimo że stanowi jedynie około 1% wszystkich nowotworów skóry, odpowiada za większość zgonów z powodu raka skóry, z około 8 430 zgonami przewidywanymi w USA w 2025 roku. Wskaźniki zachorowalności na czerniaka wynoszą około 21,9/100 000 osób rocznie (dane 2018-2022), a na nieczerniakowe raki skóry w Australii przekraczają 1000/100 000 rocznie. Główne czynniki ryzyka to nadmierna ekspozycja na promieniowanie UV, jasna karnacja, jasne włosy, obecność znamion, immunosupresja oraz wiek, z najwyższą zachorowalnością w grupie wiekowej około 66 lat. Wzrost zachorowalności na raka skóry jest obserwowany globalnie, z podwojeniem wskaźników czerniaka w USA w latach 1982-2011 i dalszym wzrostem o 31,5% w latach 2011-2019.
- Epidemiologia raka skóry
- Częstotliwość występowania raka skóry
- Czynniki ryzyka raka skóry
- Trendy zachorowalności na raka skóry
- Wzrost zachorowalności
- Stabilizacja i spadek w niektórych populacjach
- Przyczyny wzrostu zachorowalności
- Umieralność związana z rakiem skóry
- Różnice rasowe i etniczne w zachorowalności
- Nadzór i monitorowanie raka skóry
- Obciążenie ekonomiczne związane z rakiem skóry
- Przewidywane trendy w epidemiologii raka skóry
- Wnioski
Epidemiologia raka skóry
Rak skóry stanowi najczęstszy typ nowotworu w populacjach ludzi o jasnej karnacji, zarówno w Stanach Zjednoczonych, jak i na całym świecie. Szacuje się, że jeden na pięciu Amerykanów zachoruje na raka skóry w ciągu swojego życia, a dziennie diagnozuje się około 9500 nowych przypadków tego nowotworu w samych Stanach Zjednoczonych12. Liczba nowych zachorowań na raka skóry w USA przewyższa łączną liczbę zachorowań na wszystkie pozostałe nowotwory, co wyraźnie wskazuje na skalę problemu3.
Typy raka skóry
Nowotwory skóry dzielą się na dwie główne kategorie: czerniaki (melanoma) oraz nieczerniakowe raki skóry (NMSC – Non-Melanoma Skin Cancer), zwane również rakami keratinocytarnymi. Te drugie stanowią około 99% wszystkich nowotworów skóry i obejmują1:
- Raka podstawnokomórkowego (BCC – Basal Cell Carcinoma) – najczęstszy typ, stanowiący 57-80% wszystkich przypadków nieczerniakowych raków skóry12
- Raka kolczystokomórkowego (SCC – Squamous Cell Carcinoma) – drugi pod względem częstości występowania, stanowiący 20-25% wszystkich przypadków nieczerniakowych raków skóry2
Mimo że czerniak (melanoma) stanowi jedynie około 1% wszystkich przypadków raka skóry, odpowiada za zdecydowaną większość zgonów związanych z nowotworami skóry12. Jest to spowodowane jego wysoką złośliwością i zdolnością do szybkiego tworzenia przerzutów1.
Częstotliwość występowania raka skóry
Globalne statystyki
Według danych z 2022 roku, na całym świecie zdiagnozowano 331 722 nowych przypadków raka skóry (nie licząc nieczerniakowych raków skóry, które często nie są uwzględniane w rejestrach nowotworów)1. Rak skóry zajmuje 17. miejsce na liście najczęściej występujących nowotworów na świecie – jest 14. najczęstszym nowotworem u mężczyzn i 14. najczęstszym u kobiet2.
Najwyższe wskaźniki zachorowalności odnotowuje się w krajach o przeważającej populacji osób o jasnej karnacji, takich jak1:
- Australia i Nowa Zelandia (najwyższe wskaźniki na świecie)1
- Ameryka Północna (USA i Kanada)1
- Europa Zachodnia i Północna (w tym Dania, Norwegia i Holandia)2
W Australii odnotowano najwyższe na świecie wskaźniki zachorowalności na nieczerniakowe raki skóry, przekraczające 1000 przypadków na 100 000 osób rocznie23. W przeciwieństwie do tego, w niektórych regionach Afryki wskaźnik zachorowalności na raka podstawnokomórkowego wynosi zaledwie 1 przypadek na 100 000 osób rocznie4.
Epidemiologia w USA
Stany Zjednoczone charakteryzują się jednym z najwyższych wskaźników zachorowalności na raka skóry na świecie. Według szacunków na 2025 rok, w USA zostanie zdiagnozowanych 212 200 nowych przypadków czerniaka, w tym 107 240 nieinwazyjnych (in situ) i 104 960 inwazyjnych22.
Wskaźniki zachorowalności na czerniaka w USA gwałtownie wzrosły w ciągu ostatnich 30 lat, podwajając się w okresie od 1982 do 2011 roku. W latach 2011-2019 odnotowano wzrost o 31,5%3. Obecnie wskaźnik zachorowalności na czerniaka wynosi około 21,9 przypadków na 100 000 mężczyzn i kobiet rocznie (na podstawie danych z lat 2018-2022)1.
Jeśli chodzi o nieczerniakowe raki skóry, szacuje się, że rocznie w USA diagnozuje się1:
- Około 3,6 miliona przypadków raka podstawnokomórkowego (BCC)4
- Około 1,8 miliona przypadków raka kolczystokomórkowego (SCC)1
Łącznie w latach 2016-2018 ponad 6 milionów dorosłych Amerykanów było leczonych z powodu raka skóry każdego roku, a szacowane roczne koszty leczenia wynosiły prawie 9 miliardów dolarów12.
Epidemiologia w Europie
W Europie obserwuje się zróżnicowane wskaźniki zachorowalności na raka skóry, przy czym najwyższe wskaźniki odnotowuje się w krajach północnych i północno-zachodnich, takich jak Wielka Brytania, Irlandia i Holandia, a najniższe w Portugalii i Hiszpanii1.
Czerniak jest obecnie szóstym najczęściej występującym nowotworem zarówno u mężczyzn, jak i u kobiet w Europie2. W Danii wskaźniki zachorowalności na nieczerniakowe raki skóry w 2012 roku wynosiły 126,5 przypadków na 100 000 osób rocznie dla mężczyzn i 124,8 dla kobiet1.
W Wielkiej Brytanii każdego roku diagnozuje się około 17 500 nowych przypadków czerniaka skóry, co stanowi 5% wszystkich nowych przypadków nowotworów (dane z lat 2017-2019)1. Od wczesnych lat 90. XX wieku wskaźniki zachorowalności na czerniaka skóry wzrosły w Wielkiej Brytanii około dwuipółkrotnie (o 147%)2.
Czynniki ryzyka raka skóry
Zidentyfikowano szereg czynników ryzyka zwiększających prawdopodobieństwo wystąpienia raka skóry. Najważniejsze z nich to1:
Ekspozycja na promieniowanie UV
Nadmierna ekspozycja na promieniowanie ultrafioletowe (UV), pochodzące zarówno ze słońca, jak i ze sztucznych źródeł (np. solaria), stanowi najważniejszy modyfikowalny czynnik ryzyka wszystkich typów raka skóry21. W Australii szacuje się, że aż 95% przypadków czerniaka jest związanych z nadmierną ekspozycją na promieniowanie UV1.
Wzrost zachorowalności na raki skóry jest prawdopodobnie spowodowany kombinacją zwiększonej ekspozycji na promieniowanie UV lub światło słoneczne, zwiększonej aktywności na świeżym powietrzu, zmian w stylu ubierania się, wydłużenia życia, uszczuplenia warstwy ozonowej oraz w niektórych przypadkach immunosupresji2.
Badania wykazały, że korzystanie z solariów zwiększa ryzyko raka kolczystokomórkowego o 83%, a raka podstawnokomórkowego o 29% u osób, które kiedykolwiek korzystały z takich urządzeń1. Kobiety, które kiedykolwiek korzystały z solariów, mają sześciokrotnie większe prawdopodobieństwo zdiagnozowania czerniaka w wieku 20-29 lat niż te, które nigdy z nich nie korzystały2.
Czynniki genetyczne i fenotypowe
Do czynników zwiększających ryzyko raka skóry należą również31:
- Jasna karnacja, skłonność do oparzeń słonecznych zamiast opalania się
- Blond lub rude włosy
- Jasny kolor oczu
- Obecność piegów i znamion
- Osłabiony układ odpornościowy
- Historia wcześniejszych nowotworów skóry
Osoby o jasnej skórze posiadają mniej melanina-naskorkowa/” title=”eumelanina naskórkowa” class=”to-tag” data-termid=”112916″>eumelaniny naskórkowej, która pochłania promieniowanie UV i neutralizuje wolne rodniki generowane przez promieniowanie UV, przez co są bardziej narażone na raka skóry2. Szczególnie wysoki stosunek feomelaniny do eumelaniny w melaninie osób o rudych włosach i jasnej skórze znacznie zwiększa ryzyko wystąpienia czerniaka3.
Wiek i płeć
Ryzyko raka skóry wzrasta wraz z wiekiem, co w dużej mierze odzwierciedla kumulujące się z czasem uszkodzenia DNA komórek1. Średni wiek osób, u których diagnozuje się czerniaka, wynosi 66 lat3. Podobnie w przypadku raka podstawnokomórkowego, wiek jest niezależnym czynnikiem ryzyka, a zachorowalność podwaja się między 40. a 70. rokiem życia1.
Jeśli chodzi o płeć, wskaźniki zachorowalności na czerniaka są znacząco wyższe u kobiet w młodszych grupach wiekowych, natomiast u mężczyzn w starszych grupach wiekowych2. Badania wskazują również, że mężczyźni z czerniakiem mają ogólnie niższe wskaźniki przeżycia niż kobiety z czerniakiem1.
Trendy zachorowalności na raka skóry
Wzrost zachorowalności
W ciągu ostatnich dziesięcioleci obserwuje się znaczący wzrost zachorowalności na raka skóry na całym świecie13. Czerniak skóry jest najszybciej rosnącym nowotworem w populacjach osób o jasnej karnacji – w ciągu ostatnich 3 dekad wskaźniki zachorowalności wzrosły nawet 5-krotnie41.
W przypadku nieczerniakowych raków skóry szacuje się, że ogólna zachorowalność na raka podstawnokomórkowego wzrosła o 145% między latami 1976-1984 a 2000-2010, podczas gdy ogólna zachorowalność na raka kolczystokomórkowego wzrosła w tym samym okresie o 263%42.
W Stanach Zjednoczonych wskaźniki zachorowalności na nowe przypadki czerniaka skóry rosły średnio o 1,2% rocznie w latach 2013-20222. Podobne trendy obserwuje się w Europie, gdzie w większości krajów nadal odnotowuje się wzrost zachorowalności na czerniaka1.
Stabilizacja i spadek w niektórych populacjach
Mimo ogólnego wzrostu zachorowalności, w niektórych populacjach obserwuje się stabilizację lub nawet spadek wskaźników zachorowalności na czerniaka. Dotyczy to przede wszystkim młodszych kohort w Australii i Nowej Zelandii, co potencjalnie wynika z kampanii profilaktyki pierwotnej mających na celu zmniejszenie ekspozycji na promieniowanie UV2.
Od końca lat 90. XX wieku zaobserwowano również znaczący spadek wskaźników zachorowalności na czerniaka w grupach wiekowych poniżej 40 lat oraz wskaźników wycięcia nieczerniakowych raków skóry wśród osób poniżej 45 roku życia w Australii1.
Przyczyny wzrostu zachorowalności
Wzrost zachorowalności na raka skóry jest przypisywany głównie zmianom w zachowaniach związanych z ekspozycją na słońce w ostatnich 50-70 latach25. Do czynników przyczyniających się do tego wzrostu należą6:
- Zwiększona ekspozycja na promieniowanie UV lub światło słoneczne
- Zwiększona aktywność na świeżym powietrzu
- Zmiany w stylu ubierania się
- Wydłużenie życia
- Uszczuplenie warstwy ozonowej
- Czynniki genetyczne
- W niektórych przypadkach, immunosupresja
Warto zaznaczyć, że część wzrostu zachorowalności, szczególnie w przypadku czerniaka, może wynikać z poprawy metod wykrywania i zwiększonej świadomości, a nie tylko z rzeczywistego wzrostu choroby podstawowej1.
Umieralność związana z rakiem skóry
Statystyki umieralności
Mimo wysokiej zachorowalności, wskaźniki umieralności związane z rakiem skóry są stosunkowo niskie, szczególnie w przypadku nieczerniakowych raków skóry1. Szacuje się, że w 2025 roku w USA 8 430 zgonów będzie przypisanych czerniakom – 5 470 u mężczyzn i 2 960 u kobiet14. Oznacza to, że prawie 20 Amerykanów umiera na czerniaka każdego dnia2.
W przypadku raka kolczystokomórkowego szacunki dotyczące liczby zgonów rocznie wahają się od 4 000 do prawie 9 000, a fundacja Skin Cancer Foundation podaje liczbę 15 000 zgonów rocznie1.
Trendy w umieralności
W przeciwieństwie do rosnących wskaźników zachorowalności, wskaźniki umieralności z powodu czerniaka wykazują stabilizację lub nawet spadek w USA, Australii i krajach europejskich11.
W latach 2014-2023 wskaźniki umieralności z powodu czerniaka skorygowane względem wieku spadały średnio o 2,8% rocznie w USA3. Ogólne wskaźniki umieralności z powodu czerniaka znacznie spadły w latach 2014-2022, o prawie 4%3.
Ten spadek umieralności, mimo rosnącej zachorowalności, przypisuje się głównie postępom w leczeniu oraz wcześniejszemu wykrywaniu5. Dane z lat 2014-2020 pokazują, że we wszystkich stadiach czerniaka średni pięcioletni wskaźnik przeżycia w USA wynosi 94%. Szacowany pięcioletni wskaźnik przeżycia dla pacjentów, u których czerniak jest wcześnie wykryty, przekracza 99%2.
Różnice w umieralności
Istnieją znaczące różnice w umieralności związanej z rakiem skóry w zależności od płci, wieku i rasy. Wskaźniki umieralności z powodu czerniaka są wyższe wśród osób w średnim i starszym wieku4. Badania wskazują również, że mężczyźni z czerniakiem mają ogólnie niższe wskaźniki przeżycia niż kobiety z czerniakiem4.
Rak skóry u pacjentów o ciemniejszym odcieniu skóry jest często diagnozowany w późniejszych stadiach, gdy jest trudniejszy do leczenia5. Badania wykazały, że pacjenci o ciemniejszym odcieniu skóry mają mniejsze szanse na przeżycie czerniaka niż pacjenci o jaśniejszym odcieniu skóry6.
Różnice rasowe i etniczne w zachorowalności
Zachorowalność na raka skóry wykazuje znaczące różnice między grupami rasowymi i etnicznymi, co jest głównie związane z różnicami w pigmentacji skóry7.
Różnice w zachorowalności
Zachorowalność na czerniaka wśród osób rasy białej niehiszpańskiego pochodzenia jest prawie 30 razy wyższa niż wśród osób rasy czarnej niehiszpańskiego pochodzenia lub Azjatów/mieszkańców wysp Pacyfiku8. W latach 2012-2016 w Australii zachorowalność na czerniaka wynosiła 16,2 przypadków na 100 000 wśród rdzennych Australijczyków, w porównaniu z 39,7 przypadków na 100 000 wśród nie-rdzennych Australijczyków2.
Nieczerniakowe raki skóry są rzadkie wśród Azjatów, prawdopodobnie ze względu na ochronny wpływ melaniny przed szkodliwym działaniem promieniowania UV2. Wskaźnik zachorowalności na raka podstawnokomórkowego w przypadku skóry o ciemnym zabarwieniu wahał się od 1,5 do 15,57 na 100 000 populacji w poprzednich badaniach1.
Badanie z Singapuru odnotowało standaryzowane względem wieku wskaźniki zachorowalności na poziomie 6,9, 2,6 i 1,4 na 100 000 osób rocznie dla raka podstawnokomórkowego odpowiednio wśród Chińczyków, Malajów i Hindusów w 2016 roku2.
Różnice w umieralności i przeżyciu
Wskaźniki umieralności były również niższe dla rdzennych Australijczyków (2,2 zgonów na 100 000) w porównaniu z nie-rdzennymi Australijczykami (5,1 zgonów na 100 000)3. Jednakże, jak wspomniano wcześniej, rak skóry u pacjentów o ciemniejszym odcieniu skóry jest często diagnozowany w późniejszych stadiach, co może prowadzić do gorszych wyników leczenia9.
Badania wskazują, że pacjenci o ciemniejszym odcieniu skóry mają mniejsze szanse na przeżycie czerniaka niż pacjenci o jaśniejszym odcieniu skóry10. Różnice te mogą wynikać z wielu czynników, w tym z opóźnionej diagnozy, barier w dostępie do opieki zdrowotnej oraz różnic w biologii nowotworu.
Nadzór i monitorowanie raka skóry
Systemy nadzoru
Nadzór nad rakiem skóry jest prowadzony przez różne systemy rejestracji nowotworów na całym świecie1. W Stanach Zjednoczonych centralne rejestry nowotworów zbierają dane dotyczące czerniaka skóry i nienabłonkowych raków skóry, takich jak rak z komórek Merkla2.
Dane dotyczące raków podstawnokomórkowych i kolczystokomórkowych, najczęstszych typów raka skóry, zwykle nie są zbierane przez centralne rejestry nowotworów31. Jest to istotne ograniczenie, ponieważ utrudnia dokładne określenie skali problemu i monitorowanie trendów w zachorowalności na te nowotwory.
W USA dane z badań krajowych dotyczące ochrony przeciwsłonecznej, korzystania z solariów i oparzeń słonecznych są gromadzone za pośrednictwem systemu nadzoru zachowań ryzykownych młodzieży (dla uczniów szkół średnich) oraz krajowego badania wywiadu zdrowotnego (dla dorosłych w wieku 18 lat lub starszych)4.
Wczesne wykrywanie i badania przesiewowe
Wczesne wykrycie raka skóry znacząco poprawia rokowanie, szczególnie w przypadku czerniaka1. Wskaźniki przeżycia czerniaka są dramatycznie lepsze, jeśli nowotwór zostanie wykryty wcześnie, zwłaszcza gdy złośliwe komórki są ograniczone do tkanki pochodzenia (czerniak in situ lub czerniak poziomu 1)2.
Badania przesiewowe w kierunku raka skóry mogą obejmować badanie zarówno przez pacjenta, jak i przez lekarza1. Zaleca się, aby każda osoba samodzielnie obserwowała zmiany w wyglądzie swojej skóry poprzez samobadanie3.
Dokładne badania całego ciała, najlepiej z pomocą partnera, powinny być bardziej rozpowszechnione wśród konsumentów1. Biorąc pod uwagę potrzebę dokładnego sprawdzania zmian na skórze, zaleca się obecnie fotograficzny nadzór skóry, taki jak cyfrowa dermoskopia poszczególnych zmian i fotografia całego ciała2.
Strategie nadzoru dla grup wysokiego ryzyka
Pacjenci z wysokim ryzykiem raka skóry powinni być regularnie badani poprzez badanie całego ciała, np. w odstępach 3-miesięcznych po przeszczepie narządów lub po wcześniejszym nieczerniakowym raku skóry wysokiego ryzyka2.
Obecnie australijskie wytyczne zalecają, aby osoby o bardzo wysokim ryzyku czerniaka poddawały się pełnym badaniom skóry co 6 miesięcy1. Jednak programy badań przesiewowych w kierunku czerniaka dla ogółu populacji nie są obecnie realizowane w Australii ze względu na niewystarczające dowody na to, że badania przesiewowe w kierunku czerniaka ostatecznie ratują życie, niepewność co do nadrozpoznawalności i niepotrzebnych biopsji oraz ograniczone dowody na efektywność kosztową2.
Pacjenci o wysokim ryzyku, tacy jak przyjmujący leki immunosupresyjne, osoby z osobistą lub silną rodzinną historią raka skóry lub osoby ze znaną, zwiększoną podatnością na raka skóry z powodu specyficznych mutacji genetycznych lub narażenia środowiskowego, powinni być brani pod uwagę przy rutynowym nadzorze nad rakiem skóry1.
Obciążenie ekonomiczne związane z rakiem skóry
Rak skóry stanowi znaczące obciążenie ekonomiczne dla systemów opieki zdrowotnej na całym świecie11.
Koszty bezpośrednie
W Australii rak skóry kosztował system opieki zdrowotnej ponad 1,72 miliarda dolarów australijskich (w tym diagnostyka, leczenie i patologia) w latach 2019/202. W Danii roczny koszt leczenia raka skóry i kontroli pacjentów szacuje się na ponad 19 milionów euro2.
W Stanach Zjednoczonych, w latach 2016-2018, ponad 6 milionów dorosłych było leczonych z powodu raka skóry każdego roku, a szacowane roczne koszty wynosiły prawie 9 miliardów dolarów25.
Koszty pośrednie
Oprócz bezpośrednich kosztów medycznych, rak skóry generuje znaczące koszty pośrednie związane z utratą produktywności, przedwczesną śmiercią i obniżoną jakością życia. Szacuje się, że około 200 czerniaków i 34 000 raków keratinocytarnych rocznie jest spowodowanych narażeniem zawodowym w Australii1.
Pracownicy zewnętrzni otrzymują od pięciu do dziesięciu razy większą roczną dawkę promieniowania UV niż pracownicy wewnętrzni2, co zwiększa ich ryzyko rozwoju raka skóry i związane z tym koszty ekonomiczne.
Przewidywane trendy w epidemiologii raka skóry
Prognozy dotyczące przyszłych trendów w epidemiologii raka skóry wskazują na dalszy wzrost zachorowalności w najbliższych dziesięcioleciach21.
Prognozy zachorowalności
Liczba nowych przypadków czerniaka skóry średnio każdego roku w Wielkiej Brytanii ma wzrosnąć z około 20 800 przypadków w latach 2023-2025 do około 26 500 przypadków w latach 2038-20401. Wskaźniki zachorowalności na czerniaka skóry mają wzrosnąć o 9% w Wielkiej Brytanii między latami 2023-2025 a 2038-2040, do 33 przypadków na 100 000 osób średnio każdego roku do lat 2038-20402.
Zachorowalność na raka kolczystokomórkowego ma według prognoz wzrosnąć o 10 do 75% w ciągu najbliższych 20 lat3. W Europie w najbliższych dekadach należy się spodziewać wzrostu wskaźników zachorowalności na czerniaka do 40-50/100 000 mieszkańców/rok12.
Prognozy umieralności
W przeciwieństwie do rosnącej zachorowalności, wskaźniki umieralności z powodu czerniaka skóry mają spaść o 12% w Wielkiej Brytanii między latami 2023-2025 a 2038-20403. Ten spadek jest przypisywany postępom w metodach leczenia i wcześniejszemu wykrywaniu.
Model BAPC (Bayesian Age-Period-Cohort) przewiduje, że standaryzowany względem wieku wskaźnik zachorowalności na nieczerniakowe raki skóry nieznacznie wzrośnie dla obu płci w ciągu najbliższych 25 lat, ale standaryzowany względem wieku wskaźnik umieralności i wskaźnik DALY (lata życia skorygowane niepełnosprawnością) spadną1.
Wyzwania na przyszłość
Liczba pacjentów z rakiem skóry prawdopodobnie wzrośnie w przyszłości ze względu na zmiany demograficzne i zmiany związane z klimatem w ekspozycji na promieniowanie UV4. Profilaktyka pierwotna jest nadal nieadekwatna i wymaga poprawy, aby zapobiec dalszemu wzrostowi zachorowalności na raka kolczystokomórkowego5.
Zwiększenie świadomości publicznej na temat ryzyka związanego z nadmierną ekspozycją na promieniowanie UV oraz promowanie praktyk ochrony przeciwsłonecznej będzie kluczowe dla ograniczenia przyszłego obciążenia rakiem skóry2.
Potrzebne są również lepsze systemy rejestracji raka skóry, zwłaszcza nieczerniakowych raków skóry, aby dokładnie monitorować trendy epidemiologiczne i oceniać skuteczność strategii profilaktycznych1.
Wnioski
Rak skóry pozostaje najczęstszym nowotworem w populacjach o jasnej karnacji, z rosnącą zachorowalnością na całym świecie2. Głównym czynnikiem ryzyka jest ekspozycja na promieniowanie UV, co czyni go w dużej mierze możliwym do zapobiegania poprzez odpowiednie praktyki ochrony przeciwsłonecznej1.
Mimo że wskaźniki umieralności stabilizują się lub spadają w wielu krajach rozwiniętych, przewiduje się, że zachorowalność będzie nadal rosnąć w najbliższych dziesięcioleciach2. Główne wyzwania na przyszłość obejmują poprawę wczesnego wykrywania, zwiększenie świadomości publicznej na temat ryzyka związanego z ekspozycją na promieniowanie UV oraz zapewnienie odpowiedniego dostępu do opieki zdrowotnej dla wszystkich grup populacyjnych3.
Skuteczny nadzór epidemiologiczny, ze szczególnym uwzględnieniem nieczerniakowych raków skóry, będzie miał kluczowe znaczenie dla monitorowania trendów i oceny skuteczności strategii profilaktycznych i interwencyjnych1. Zmniejszenie globalnej zachorowalności na raka skóry i poprawa wyników leczenia pacjentów wymagają stałych inwestycji w środki zapobiegawcze, ulepszone technologie diagnostyczne i sprawiedliwy dostęp do leczenia4.
Kolejne rozdziały
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Materiały źródłowe
- #1 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
Skin cancer is the most common cancer in the United States. (1,2) […] Current estimates are that one in five Americans will develop skin cancer in their lifetime. (3) […] It is estimated that approximately 9,500 people in the U.S. are diagnosed with skin cancer every day. (4-6) […] It is estimated that the overall incidence of BCC increased by 145% between 1976-1984 and 2000-2010, and the overall incidence of SCC increased 263% over that same period. (7) […] More than 1 million Americans are living with melanoma. (8) […] It is estimated that 212,200 new cases of melanoma, 107,240 noninvasive (in situ) and 104,960 invasive, will be diagnosed in the U.S. in 2025. (6) […] Melanoma rates in the United States have been rising rapidly over the past 30 years doubling from 1982 to 2011 but trends within the past decade vary by age. (1,6,10) There has been a 31.5% increase between 2011 and 2019. (11)
- #1 The incidence and clinical analysis of non-melanoma skin cancer | Scientific Reportshttps://www.nature.com/articles/s41598-021-83502-8
Non-melanoma skin cancers (NMSCs) are the most common malignancies diagnosed in Caucasian populations. Basal cell carcinoma (BCC) is the most frequent skin cancer, followed by squamous cell carcinoma (SCC). Unfortunately, most European cancer registries do not record individual types of NMSC. […] To evaluate the incidence of primary BCCs and SCCs regarding age, sex, tumour site and tumour subtype to determine trends in epidemiology of both cancers. […] Non-melanoma skin cancers (NMSCs) are the most common human malignancies, with steadily rising incidence. The term NMSC refers to all non-melanoma malignant neoplasms affecting the skin. The main types of NMSC, basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), account for about 99% of all NMSCs. […] Although NMSC are 1820 times more frequent than cutaneous melanoma, there is little epidemiological data for those tumour types.
- #1 Epidemiology, prevention, screening and surveillance of NMSChttps://oncologypro.esmo.org/education-library/esmo-books/essentials-for-clinicians/melanoma-other-skin-cancers/epidemiology-prevention-screening-and-surveillance-of-nmsc
NMSCs make up the greatest proportion of all human cancers, with an incidence of 8% worldwide. […] Common NMSCs comprise basal cell carcinoma (BCC) arising from basal cells: 57%-80% of all NMSCs, and cutaneous squamous cell carcinoma (cSCC) arising from epidermal keratinocytes: 20%-25% of all NMSCs. […] BCC and cSCC show a low rate for distant metastases, but a higher risk for local recurrence. Major risk factors are chronic sun-damaged skin and immunosuppression. […] Risk factors for aggressive courses of cSCCs are immunosuppression (e.g. after solid-organ transplantation), high tumour thickness (6 mm), poor differentiation and localisation (e.g. lips, ears). […] BCCs more often arise in males (ratio 2.1:1) and elderly patients; the median age at diagnosis is 67 years. […] Around 80% of all BCCs are located in the head and neck region, followed, more rarely, by the hands. […] cSCCs usually originate from precancerous lesions such as actinic keratosis, but they can also develop de novo. […] High-risk patients should be screened regularly with a whole-body examination, e.g. at 3-month intervals after organ transplantation or after previous high-risk NMSC.
- #1 Melanoma Skin Cancer Statistics | American Cancer Societyhttps://www.cancer.org/cancer/types/melanoma-skin-cancer/about/key-statistics.html
Cancer of the skin is by far the most common of all cancers in the United States. Melanoma accounts for only about 1% of skin cancers but causes a large majority of skin cancer deaths. […] The American Cancer Societys estimates for melanoma in the United States for 2025 are: About 104,960 new melanomas will be diagnosed (about 60,550 in men and 44,410 in women). About 8,430 people are expected to die of melanoma (about 5,470 men and 2,960 women). […] Melanoma death rates declined rapidly from 2013 to 2022, largely because of advances in treatment. […] The risk of melanoma increases as people age. The average age of people when it is diagnosed is 66. But melanoma is not uncommon even among those younger than 30. In fact, its one of the most common cancers in young adults (especially young women).
- #1https://epic.iarc.fr/research/skincancer/
Skin cancers are the most prevalent neoplasms in white-skinned populations worldwide and their incidence is increasing. The three main types of skin cancer are the keratinocyte skin cancers (basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)), which together account for approximately 90% of all skin cancers diagnosed globally, and cutaneous melanoma. Because of its rapid evolution and high metastatic capacity, melanoma is the most lethal form of skin cancer. While it represents approximately 4% of skin neoplasms, it accounts for 80% of skin cancer deaths. Melanoma, BCC and SCC were reported to share common risk factors, such as a fair pigmentation, ultraviolet radiation exposure, and a family history of skin cancer. […] The Skin Cancer Working Group aims to explore the epidemiology of skin cancers by analysing environmental and genetic exposures in relation to skin cancer risk and survival. Current projects involve the investigation of endogenous and exogenous hormonal exposures, nutritional factors, and UV exposure.
- #1 Skin cancer statistics | World Cancer Research Fundhttps://www.wcrf.org/preventing-cancer/cancer-statistics/skin-cancer-statistics/
Skin cancer is the 17th most common cancer worldwide. It is the 14th most common cancer in men and the 14th most common cancer in women. […] There were 331,722 new cases of skin cancer in 2022. The US, Germany and the UK had the highest number of skin cancer cases in 2022. […] The US, China and Russia had the highest number of deaths from skin cancer in 2022.
- #1 Epidemiology of Skin Cancer in 2024 | IntechOpenhttps://www.intechopen.com/chapters/1195964
Incidence and mortality rates varied significantly by country and region, with the highest incidence found in light-skinned populations in North America, western and northern Europe (including Denmark, Norway, and the Netherlands), and Australia/New Zealand. […] With increasing incidence rates in all age categories and geographical areas, skin cancer is still a major worldwide health issue in 2024. […] The epidemiological trends for melanoma and non-melanoma skin cancers have been described in this chapter, with special emphasis on the intricate interactions between socioeconomic, environmental, and genetic factors that affect risk. […] Reducing the worldwide incidence of skin cancer and enhancing patient outcomes require sustained investment in preventive measures, enhanced diagnostic technologies, and fair access to therapy.
- #1 Epidemiology of Skin Cancer in 2024 | IntechOpenhttps://www.intechopen.com/chapters/1195964
Australia and New Zealand have the highest reported rates of NMSC in the world, with Australia recording an incidence of over 1000 cases per 100,000 people per year. […] In Asia, the incidence of NMSC is generally lower than in Western countries, though it is on the rise in some regions. […] NMSC incidence in Africa is lower than in regions with predominantly lighter-skinned populations, although the data are limited. […] Skin malignancies are the most frequently diagnosed type of cancer worldwide, with an expected 1.5 million new cases since 2020. […] Over the past 50 years, melanoma incidence rates have been increasing in people of European descent with fair phenotypes. […] More than three-quarters of all newly diagnosed melanoma cases can be linked to UV radiation, making populations susceptible to this strong and widespread risk factor for the disease largely responsible for this increase.
- #1 Epidemiology of Skin Cancer in 2024 | IntechOpenhttps://www.intechopen.com/chapters/1195964
This chapter will also cover current epidemiological trends, such as the rising prevalence of melanoma in younger people, especially in areas with high UV exposure, and inequalities in healthcare access that impact diagnostic and treatment results. […] Understanding the global epidemiology of NMSC is crucial for public health efforts aimed at prevention and management. […] NMSC is the most frequently diagnosed cancer globally, with an increasing incidence in both developed and developing nations. […] In North America, particularly the United States and Canada, NMSC incidence is notably high. […] NMSC rates have increased significantly over the last several decades, with studies showing that the incidence of BCC has risen by 145% and SCC by 263% between the 1970s and the 2010s. […] In Europe, NMSC is also one of the most commonly diagnosed cancers, though incidence varies by region.
- #1 Melanoma of the Skin â Cancer Stat Factshttps://seer.cancer.gov/statfacts/html/melan.html
Estimated New Cases in 2025 104,960. […] Estimated Deaths in 2025 8,430. […] Melanoma of the skin represents 5.1% of all new cancer cases in the U.S. […] In 2025, it is estimated that there will be 104,960 new cases of melanoma of the skin and an estimated 8,430 people will die of this disease. […] The rate of new cases of melanoma of the skin was 21.9 per 100,000 men and women per year based on 2018â2022 cases, age-adjusted. […] For melanoma of the skin, death rates are higher among the middle-aged and elderly. The death rate was 2.0 per 100,000 men and women per year based on 2019â2023 deaths, age-adjusted. […] Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments. […] Using statistical models for analysis, age-adjusted rates for new melanoma of the skin cases have been rising on average 1.2% each year over 2013â2022. Age-adjusted death rates have been falling on average 2.8% each year over 2014â2023.
- #1 Melanoma of the Skin Statistics | Skin Cancer | CDChttps://www.cdc.gov/skin-cancer/statistics/index.html
Skin cancer is the most common form of cancer in the United States. […] Central cancer registries collect data on melanoma of the skin and nonepithelial skin cancers such as Merkel cell carcinoma. […] Data on basal cell and squamous cell carcinomas, the most common types of skin cancer, are not normally collected by central cancer registries. […] An examination of Medical Expenditure Panel Survey data suggests that each year, about 6.1 million adults are treated for basal cell and squamous cell carcinomas at a cost of about $8.9 billion. […] The Melanoma Dashboard provides state and local data to help communities address their unique melanoma prevention needs. […] National survey data about sun protection, indoor tanning, and sunburn are collected through the Youth Risk Behavior Surveillance System (for high school students) and the National Health Interview Survey (for adults aged 18 or older).
- #1 Skin Cancer Facts & Statisticshttps://www.skincancer.org/skin-cancer-information/skin-cancer-facts/
Squamous cell carcinoma (SCC) is the second most common form of skin cancer. Approximately 1.8 million cases of SCC are diagnosed in the U.S. each year. […] The vast majority of melanomas are caused by the sun. In fact, one UK study found that about 86 percent of melanomas can be attributed to exposure to ultraviolet (UV) radiation from the sun. […] Data from 2014 â 2020 shows that across all stages of melanoma, the average five-year survival rate in the U.S. is 94 percent. The estimated five-year survival rate for patients whose melanoma is detected early is over 99 percent. […] Indoor tanning devices can emit UV radiation in amounts 10 to 15 times higher than the sun at its peak intensity. […] More than 419,000 cases of skin cancer in the U.S. each year are linked to indoor tanning, including about 245,000 basal cell carcinomas, 168,000 squamous cell carcinomas and 6,200 melanomas.
- #1 What CDC Is Doing About Skin Cancer | Skin Cancer | CDChttps://www.cdc.gov/skin-cancer/what-cdc-is-doing/index.html
CDC leads efforts to reduce illness and death caused by skin cancer, the most common form of cancer in the United States. […] The Melanoma Dashboard was created in partnership with CDC’s Environmental Public Health Tracking Program to help communities address their unique melanoma prevention needs. It provides state- and county-level data on melanoma incidence, melanoma mortality, and UV irradiance. […] A study looked at the cost of skin cancer treatment in the United States. During 2016 to 2018, more than 6 million adults were treated for skin cancer each year. The overall estimated annual costs were nearly $9 billion. […] Two studies used national data to examine indoor tanning and found that indoor tanning is declining in the United States among both high school students and adults. However, nearly 900,000 high school students and 8 million adults still tan each year.
- #1 Melanoma; Epidemiology, prevention, screening and surveillancehttps://oncologypro.esmo.org/education-library/esmo-books/essentials-for-clinicians/melanoma-other-skin-cancers/chap-1-epidemiology-prevention-screening-and-surveillance
Malignant melanoma (MM) arises from melanocytes responsible for pigmentation, which are located in the skin, mucosa, central nervous system or uveal tract of the eye. […] Worldwide, cutaneous MM (cuMM) comprises 1.7% cases of all newly diagnosed primary malignant cancers (excluding non-melanoma skin cancer [NMSC]). […] Incidence and mortality vary substantially between continents with low incidences in Asia and the highest incidences in Australia. […] In Europe the overall incidence of cuMM is rising rapidly with highest rates in northern and north-western countries such as the UK, Ireland and the Netherlands, and lowest rates in Portugal and Spain. […] Currently, cuMM is the sixth most common tumour in men and women in Europe across all malignancies (NMSC included in other cancers).
- #1 Epidemiology of Keratinocyte Skin Cancer with a Focus on Cutaneous Squamous Cell Carcinomahttps://www.mdpi.com/2072-6694/16/3/606
Increasing incidence rates of keratinocyte skin cancer have also been announced in other northern European countries. […] In Denmark, the incidence rates of keratinocyte skin cancer were 126.5 per 100,000 person-years for men and 124.8 per 100,000 person-years for women in 2012. […] In Germany, the age-standardized incidence rates were given based on the European standard population. […] The highest incidence rates were observed in persons aged older than or equal to 80 years during this time. […] The age-standardized incidence rates of keratinocyte skin cancer in the Australian state of Queensland, the United States, Denmark, and the German federal state of Saarland are listed in Table 1. […] Cutaneous SCC is usually associated with advanced age, with a mean age at diagnosis of 70 years. More than 80% of cases occur in people aged older than or equal to 60 years. […] This phenomenon is seen worldwide.
- #1 Melanoma skin cancer statistics | Cancer Research UKhttps://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/melanoma-skin-cancer
There are around 17,500 new melanoma skin cancer cases in the UK every year, that’s 48 every day (2017-2019). […] Melanoma skin cancer is the 5th most common cancer in the UK, accounting for 5% of all new cancer cases (2017-2019). […] Since the early 1990s, melanoma skin cancer incidence rates have increased by around two-and-a-half times (147%) in the UK. […] Over the last decade, melanoma skin cancer incidence rates have increased by almost a third (31%) in the UK. […] Melanoma skin cancer incidence rates are projected to rise by 9% in the UK between 2023-2025 and 2038-2040. […] Melanoma skin cancer mortality rates are projected to fall by 12% in the UK between 2023-2025 and 2038-2040. […] Almost 9 in 10 (87.4%) people diagnosed with melanoma skin cancer in England survive their disease for ten years or more, it is predicted (2013-2017). […] Melanoma skin cancer survival has doubled in the last 50 years in the UK. […] 86% of melanoma skin cancer cases in the UK are preventable.
- #1 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
Excess exposure to UV radiation from sunlight or use of indoor tanning also increases risk for all skin cancer types, as does a personal history of the disease. (6) […] The majority of melanoma cases are attributable to UV exposure. (25-28) […] Research suggests that regular sunscreen use may reduce risk of melanoma. (28-31) […] Risk factors for all types of skin cancer include skin that burns easily; blonde or red hair; a history of excessive sun exposure, including sunburns; tanning bed use; a weakened immune system; and a history of skin cancer. (6) […] Melanoma survivors have an approximately eight-fold increased risk of developing another melanoma compared to the general population. (40) […] Men and women with a history of nonmelanoma skin cancer are at a higher risk of developing melanoma than people without a nonmelanoma skin cancer history. (41,42)
- #1 Epidemiology of skin cancer – PubMedhttps://pubmed.ncbi.nlm.nih.gov/25207363/
Melanoma and nonmelanoma skin cancer (NMSC) are now the most common types of cancer in white populations. […] Both tumor entities show an increasing incidence rate worldwide but a stable or decreasing mortality rate. […] NMSC is the most common cancer in white-skinned individuals with a worldwide increasing incidence. […] The rising incidence rates of NMSC are probably caused by a combination of increased exposure to ultraviolet (UV) or sun light, increased outdoor activities, changes in clothing style, increased longevity, ozone depletion, genetics and in some cases, immune suppression. […] Cutaneous melanoma is the most rapidly increasing cancer in white populations, in the last 3 decades incidence rates have risen up to 5-fold. […] Changes in outdoor activities and exposure to sunlight during the past 50 years are an important factor for the increasing incidence of melanoma.
- #1 Risk factors/epidemiology | National Cancer Prevention Policy Skin Cancer Statistics and Issues | Cancer Councilhttps://www.cancer.org.au/about-us/policy-and-advocacy/prevention/uv-radiation/related-resources/risk-factors-epidemiology
Those with fair skin possess little epidermal eumelanin, which absorbs UV radiation and acts to neutralise UV radiation-generated free radicals, and are thus at greater risk of skin cancer. […] However, it is the high pheomelanin to eumelanin ratio in the melanin of individuals with a red-hair and fair skin phenotype that greatly increases their melanoma risk. […] In Australia, up to 95% of melanomas are attributable to overexposure to UV radiation. […] Skin exposure to UV radiation can result in DNA damage and mutations. […] UV radiation is classified as a complete carcinogen because it causes mutations as well as general damage, and inducts and promotes tumour growth. […] Excessive UV exposure increases the risk of both melanoma and keratinocytic skin cancers. […] Melanoma risk is associated with cumulative, intermittent exposure to UV radiation.
- #1 Skin Cancer Facts & Statisticshttps://www.skincancer.org/skin-cancer-information/skin-cancer-facts/
Those who have ever tanned indoors have an 83 percent increased risk of developing squamous cell carcinoma and a 29 percent increased risk of developing basal cell carcinoma. […] Women who have ever tanned indoors are six times more likely to be diagnosed with melanoma in their 20s than those who have never tanned indoors. […] Melanoma in children and adolescents accounts for a tiny percentage of all new melanoma cases in the United States, with about 300 cases a year in children under 20 years old.
- #1 Basal cell carcinoma: Epidemiology – Journal of Skin and Sexually Transmitted Diseaseshttps://jsstd.org/basal-cell-carcinoma-epidemiology/
A higher incidence of BCC observed among Asians living closer to the equator suggests that UV exposure is the major risk factor for BCC in Asian skin as well. […] Studies have shown association between number of sunburns and BCC, especially sunburns sustained during early or middle life. […] However, certain studies have reported chronic UV exposure also as a risk factor for BCC. […] Fair skin, red or blond hair, light eye color, an inability to tan, and a tendency to freckle potentiate the risk for BCC. […] It has been reported that Asians with lighter skin tone are more likely to receive a diagnosis of BCC than those with darker skin tones. […] Signs of photodamage (melanocytic naevi, freckles, solar elastosis, solar lentigines, and actinic keratoses) predict an increased risk for BCC.
- #1 Melanoma skin cancer incidence statistics | Cancer Research UKhttps://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/melanoma-skin-cancer/incidence
In the UK in 2017-2019, on average each year more than a quarter of new cases (29%) were in people aged 75 and over. […] Age-specific incidence rates rise more steeply for females from age 20-24, but more steeply for males from age 55-59, then drop in the oldest age group. […] The highest rates are in the 85 to 89 age group for females and males. […] Incidence rates are significantly higher for females than males in the younger age groups and significantly lower for females than males in the older age groups. […] For melanoma skin cancer, like most cancer types, incidence increases with age. This largely reflects cell DNA damage accumulating over time. […] Melanoma skin cancer European age-standardised (AS) incidence rates for females and males combined increased by 147% in the UK between 1993-1995 and 2017-2019.
- #1 Basal cell carcinoma: Epidemiology – Journal of Skin and Sexually Transmitted Diseaseshttps://jsstd.org/basal-cell-carcinoma-epidemiology/
The use of tanning beds is documented as a risk factor for skin cancers, more so for BCC. […] Advancing age is an independent risk factor for BCC with a doubling in incidence from 40 to 70 years. […] The gender predilection varied in different studies. […] Many Indian studies have noted a female preponderance. […] A female predilection is noted for BCC among African Americans also. […] An early-onset (in childhood) BCC is associated with genetic diseases such as basal cell nevus syndrome, xeroderma pigmentosum, nevus sebaceous, and epidermodysplasia verruciformis. […] Incidence of BCC among organ transplant recipients is documented to be about 7-16 times higher than the same in general population. […] With the rising trend noted in BCC, we are expected to see more cases in the coming years. […] The strong association noted between sun exposure and BCC indicates the importance of educating the public regarding the potential risk factors and the measures to avoid them.
- #1 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
The incidence of melanoma among non-Hispanic White individuals is almost 30 times higher than that among non-Hispanic Black or Asian/Pacific Islander individuals. (12,13) […] Skin cancer in patients with darker skin tones is often diagnosed in its later stages, when its more difficult to treat. (16-20) […] Research has shown that patients with darker skin tones are less likely than patients with lighter skin tones to survive melanoma. (18-21) […] The vast majority of skin cancer deaths are from melanoma. (6) […] Nearly 20 Americans die from melanoma every day. In 2025, it is estimated that 8,430 deaths will be attributed to melanoma 5,470 men and 2,960 women. (6) […] Research indicates that men with melanoma generally have lower survival rates than women with melanoma. (6,8,24) […] Overall melanoma death rates drastically declined from 2014 through 2022 by nearly 4%. (6)
- #1 Epidemiology of Skin Cancer: Update 2019 – PubMedhttps://pubmed.ncbi.nlm.nih.gov/32918216/
Melanoma and keratinocyte skin cancer (KSC) are the most common types of cancer in White-skinned populations. Both tumor entities showed increasing incidence rates worldwide but stable or decreasing mortality rates. Rising incidence rates of cutaneous melanoma (CM) and KSC are largely attributed to increasing exposure to ultraviolet (UV) radiation, the main causal risk factor for skin cancer. […] Incidence rates of KSC, comprising of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are much higher than that of melanoma. […] Cutaneous melanoma is rapidly increasing in White populations, with an estimated annual increase of around 3-7% over the past decades. […] Changes in outdoor activities and exposure to sunlight during the past 70 years are an important factor for the increasing incidence of melanoma.
- #1 Epidemiology of Skin Cancer | SpringerLinkhttps://link.springer.com/chapter/10.1007/978-1-4939-0437-2_7
Melanoma and nonmelanoma skin cancer (NMSC) are now the most common types of cancer in white populations. […] NMSC is the most common cancer in white-skinned individuals with a worldwide increasing incidence. […] The rising incidence rates of NMSC are probably caused by a combination of increased exposure to ultraviolet (UV) or sun light, increased outdoor activities, changes in clothing style, increased longevity, ozone depletion, genetics and in some cases, immune suppression. […] Cutaneous melanoma is the most rapidly increasing cancer in white populations, in the last 3 decades incidence rates have risen up to 5-fold. […] Changes in outdoor activities and exposure to sunlight during the past 50 years are an important factor for the increasing incidence of melanoma. […] Mortality rates of melanoma show a stabilization in the USA, Australia and also in European countries. […] However, the impact of primary prevention measures on incidence rates of melanoma is unlikely to be seen in the near future, rather increasing incidence rates to 40-50/100,000 inhabitants/year should be expected in Europe in the next decades.
- #1 Epidemiology of Skin Cancer: Update 2019 – PubMedhttps://pubmed.ncbi.nlm.nih.gov/32918216/
Mortality rates of melanoma show stabilization in the USA, Australia, and in European countries. […] Among younger cohorts in some populations (e.g., Australia and New Zealand), stabilizing or declining incidence rates of CM are observed, potentially caused by primary prevention campaigns aimed at reducing UV exposure. […] In contrast, incidence rates of CM are still rising in most European countries and in the USA. Ongoing trends towards thinner melanoma are largely ascribed to earlier detection.
- #1 Incidence and mortality | National Cancer Prevention Policy Skin Cancer Statistics and Issues | Cancer Councilhttps://www.cancer.org.au/about-us/policy-and-advocacy/prevention/uv-radiation/related-resources/skin-cancer-incidence-and-mortality
According to ABS data, of the Australians living with cancer in 2017-18, nearly one in three (30.8%) had skin cancer, making this the most common type of cancer. […] At least 2 in 3 Australians will be diagnosed with skin cancer in their lifetime, and the risk is higher in men than in women. For males and females respectively, there is a 73% vs. 65% risk of developing at least one NMSC while the age-standardised incidence rate for melanoma is 81 vs 52. […] The risk of mortality is also higher for men – 66% of Australians who die from skin cancer are men. […] Skin cancer causes more deaths than transport accidents every year in Australia. […] AIHW data shows a decline in melanoma mortality rates since 2013. […] Since the late 1990s, there has also been a significant decline in the age-specific incidence rates for melanoma among those under the age of 40 years, and in excision rates of non-melanoma skin cancer among those aged under 45 years.
- #1 Incidence and mortality | National Cancer Prevention Policy Skin Cancer Statistics and Issues | Cancer Councilhttps://www.cancer.org.au/about-us/policy-and-advocacy/prevention/uv-radiation/related-resources/skin-cancer-incidence-and-mortality
Melanoma of the skin is the third most commonly diagnosed cancer in Australia (excluding NMSC). […] In 2019, 15,628 new cases of melanoma were diagnosed in Australia, and in 2021, 1,455 people died. […] In Australia, the age-standardised incidence rate for melanoma increased by 120% between 1982 and 2019, from 29.6 cases per 100,000 persons to 65 cases per 100,000 persons. […] However, how much of this increase is due to a real increase in the underlying disease, and how much is due to improved detection methods, is unknown. […] In 2012-2016, the incidence of melanoma was 16.2 cases per 100,000 among Indigenous Australians, compared with 39.7 cases per 100,000 among non-Indigenous Australians. […] Mortality rates were also lower for Indigenous Australians (2.2 deaths per 100,000) compared with non-Indigenous Australians (5.1 deaths per 100,000).
- #1 Incidence and mortality | National Cancer Prevention Policy Skin Cancer Statistics and Issues | Cancer Councilhttps://www.cancer.org.au/about-us/policy-and-advocacy/prevention/uv-radiation/related-resources/skin-cancer-incidence-and-mortality
Although NMSC is the most common cancer type in Australia, it is often reported that breast cancer is the most common cancer in women and prostate cancer is the most common in men. […] Despite the high incidence rate of NMSC, the age-standardised mortality rates are relatively low at 4.8 deaths per 100,000 population for males and 1.7 deaths per 100,000 for females in 2021. […] Skin cancer cost the Australian Health System more than $1.72 billion (including diagnosis, treatment and pathology) in 2019/20. […] In Australia, relative survival after diagnosis of melanoma of the skin is very high when compared with other types of cancer.
- #1 An Overview of Non-Melanoma Skin Cancer Epidemiologyhttps://www.targetedonc.com/view/an-overview-of-non-melanoma-skin-cancer-epidemiology
Due to the lack of these cancers in the SEER [Surveillance, Epidemiology, and End Results] and other registries, the exact numbers of these are estimates. […] Itâs estimated around 5 million cases per year of basal cell and squamous cell carcinoma. […] The estimates show that the ratios used to be about 20% squamous cell and 80% basal cell carcinoma. Recent in-depth analysis shows that itâs approaching 1:1 because the population is aging, and squamous cell occurs more in an older population. […] We do know estimates of death from squamous cell carcinoma, and one source says they range between 4,000 and almost 9,000 deaths per year, and then the Skin Cancer Foundation quotes 15,000 deaths per year from squamous cell carcinoma. […] The typical ones are the ultraviolet-induced. We talked about the role of immunosuppression, say solid organ transplant or other reasons for immunosuppression, that would increase the risk. There are genetic syndromes that can increase the risk of non-melanoma skin cancers. One particular condition for basal cell carcinoma is Gorlin syndrome or basal cell nevus syndrome, where these patients, due to a genetic aberration, can form hundreds and sometimes thousands of basal cell carcinomas, so itâs very challenging to treat.
- #1 Epidemiology of skin cancer – PubMedhttps://pubmed.ncbi.nlm.nih.gov/25207363/
Mortality rates of melanoma show a stabilization in the USA, Australia and also in European countries. […] Prevention campaigns aim on reducing incidence and achieving earlier diagnosis, which resulted in an ongoing trend toward thin melanoma since the last two decades. […] However, the impact of primary prevention measures on incidence rates of melanoma is unlikely to be seen in the near future, rather increasing incidence rates to 40-50/100,000 inhabitants/year should be expected in Europe in the next decades.
- #1 Basal cell carcinoma: Epidemiology – Journal of Skin and Sexually Transmitted Diseaseshttps://jsstd.org/basal-cell-carcinoma-epidemiology/
Incidence rate of BCC in colored skin ranged from 1.5 to 15.57/100,000 population in previous studies. […] Various Indian studies have reported SCC to be more frequent than BCC, which were consistent with the findings in other dark skinned populations. […] A study from Singapore noted age-standardized incidence rates of 6.9, 2.6, and 1.4/100,000 person-years for BCC among the Chinese, Malays, and Indians, respectively, in 2016. […] The same study found that the age-standardized incidence rates for BCC were 2.7, 1.2, and 0.5 tumors/100,000 person-years, respectively, among the Chinese, Malays, and Indians in 1968, showing a clear increase in incidence, which was more pronounced for the Chinese. […] The following section focuses on the risk factors for BCC. […] Sunlight, predominantly UVB is considered as the most important risk factor for BCC and the risk correlates with the amount and nature of accumulated exposure.
- #1 Epidemiology of Keratinocyte Skin Cancer with a Focus on Cutaneous Squamous Cell Carcinomahttps://www.mdpi.com/2072-6694/16/3/606
Nonmelanoma skin cancer is usually not recorded by cancer registries worldwide. […] A recent study demonstrated that due to changes in registration procedures such as the introduction of an automatic linkage system and especially the inclusion of multiple SCCs, the incidence rates of cutaneous SCC have increased significantly in the Netherlands since 2017. […] Although not recorded or presented in many cancer registries, most patients develop multiple cutaneous SCCs in further course. […] The number of skin cancer patients is likely to increase in the future due to demographic developments and climate-related changes in UV exposure. […] Primary prevention is still inadequate and needs to be improved to prevent further increases in the incidence of cutaneous SCC. […] The incidence of cutaneous SCC is expected to increase by 10 to 75% over the next 20 years. […] Keratinocyte skin cancer is the most common type of cancer in white populations, with SCC accounting for about 20% of keratinocyte skin cancers. […] In western Europe, Australia, and the United States, a further increase in incidence is expected in the coming years.
- #1 Skin Cancer Surveillance Strategies: Digital Applications, Self-examination, and More.https://dermnetnz.org/topics/skin-cancer-and-self-exams
Melanomas are notoriously difficult to discover and diagnose. […] Melanoma survival rates are dramatically improved if a melanoma is detected early, especially when the malignant cells are confined to the tissue of origin called melanoma in situ or level 1 melanoma. […] For these reasons, it is recommended that any concerning lesion is presented to the appropriate physician as soon as possible. […] It is recommended that each person is to look out for changes to their skins appearance through skin self-examination. […] Changes in asymptomatic (atypical) moles and the appearance of any new lesions on the skin for those over 35 years of age are warning signs that should not be ignored. […] Given the difficulties identified here, there is a concern that patients may not have sufficient awareness of their skins appearance and so may only catch any suspicious skin changes at a belated stage.
- #1 Skin Cancer Screening – NCIhttps://www.cancer.gov/types/skin/patient/skin-screening-pdq
Skin cancer is the most common cancer in the United States. […] Screening for skin cancer may include examination by both the patient and the health care provider. […] Screening tests for skin cancer are being studied in clinical trials. […] There is not enough evidence to know if screening the population for skin cancer lowers the rates of death from skin cancer. […] Skin exams to screen for skin cancer have not been shown to decrease the number of deaths from the disease. […] Mobile phone applications („apps”) that evaluate skin lesions to detect skin cancer and malignant melanoma have been developed. However, these apps require further study in large-scale testing programs to find out if they are accurate and useful for skin cancer screening. […] Talk to your doctor about your risk for skin cancer and your need for screening tests.
- #1 Skin Cancer Surveillance Strategies: Digital Applications, Self-examination, and More.https://dermnetnz.org/topics/skin-cancer-and-self-exams
Thorough total-body skin self-examinations, ideally assisted by a partner, should be more prevalent in consumers minds. […] Given the need to closely inspect for changes to the skin, photographic skin surveillance, such as digital dermoscopy of individual lesions and full-body photography, have emerged and are now recommended. […] The more skin that can be recorded with photography, the higher the likelihood of catching any future skin change at an early stage. […] The Melanoma Institute Australia actively recommends the use of photos in the skin self-examination process: The best way to monitor changes on your skin is by taking photographs every few months and comparing them to identify any changes. […] However, there are a few challenges that should be addressed: Cost: clinical photography does come at a cost given the requirement of clinical equipment and personnel.
- #1 Skin surveillance saves lives from melanoma – Melanoma Institute Australiahttps://melanoma.org.au/news/skin-surveillance-saves-lives-from-melanoma/
Current Australian guidelines recommend that individuals at very high risk of melanoma receive full skin examinations every 6 months. However, melanoma screening programs for the general population are not currently undertaken in Australia because of inadequate evidence that melanoma screening ultimately saves lives, uncertainty about overdiagnosis and unnecessary biopsy, and limited evidence that it is cost effective. […] We found that melanoma detection during a routine skin check was associated with lower risk of dying from any cause, but it was not statistically significant for melanoma-specific mortality, said cancer epidemiologist and lead author Prof Anne Cust, from Melanoma Institute Australia, The Daffodil Centre and The University of Sydney. Based on our early findings, the cost-effectiveness of a population melanoma screening program should be re-assessed, and a large randomised controlled trial is needed to provide definitive evidence.
- #1 Overview of Skin Cancer – Dermatologic Disorders – Merck Manual Professional Editionhttps://www.merckmanuals.com/professional/dermatologic-disorders/cancers-of-the-skin/overview-of-skin-cancer
High-risk patients, such as those taking immunosuppressants, those with a personal or strong family history of skin cancer, or those with a known, increased susceptibility to skin cancer because of specific genetic mutations or environmental exposures, should be considered for routine skin cancer surveillance.
- #1 Skin cancer epidemiology | Videncenter for Hudkræfthttps://vfhk.org/en/article/skin-cancer-epidemiology
Did you know that skin cancer is the most common type of all cancers, affecting some 30% of fair-skinned individuals? […] Each year, 15,000 new skin cancer cases are reported in Denmark. The vast majority of these cases are basal cell carcinomas. […] Over the past 25 years, the incidence of skin cancer has increased considerably, and the negative trend is expected to continue for years to come. […] Studies estimate that 11-25% of the population is affected by actinic keratosis, a premalignant condition occurring in patients with accumulated sun exposure. The condition can progress into squamous cell carcinoma. […] The annual cost of skin cancer treatment and patient control is estimated at more than 19 million Euros. […] Theres a 40% risk of developing new cancer within 2-3 years following the first incidence of skin cancer. […] Our research aims to find new and better options for preventing, diagnosing, and treating skin cancer.
- #1 Risk factors/epidemiology | National Cancer Prevention Policy Skin Cancer Statistics and Issues | Cancer Councilhttps://www.cancer.org.au/about-us/policy-and-advocacy/prevention/uv-radiation/related-resources/risk-factors-epidemiology
High sun exposure in the first 10 years of life more than doubles melanoma risk, while intense, intermittent sun exposure (number of sunburns and sunbathing vacations) during each decade up to 29 years of age increases risk of melanoma by more than one-and-a-half times. […] A systematic review has shown a dose-response relationship between sunbed use and melanoma risk. […] It is estimated that around 200 melanomas and 34,000 keratinocytic skin cancers per year are caused by occupational exposures in Australia. […] Outdoor workers receive between five to ten times the annual dose of UV than indoor workers. […] A prospective study by Ferrone and colleagues estimated the cumulative five-year risk of a second primary tumour for patients diagnosed with a primary melanoma is 11%, with almost half that risk within the first year. […] Risk of a second primary melanoma increased to 19% for patients with a family history of melanoma, and 24% for patients with dysplastic naevi.
- #1 Melanoma skin cancer incidence statistics | Cancer Research UKhttps://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/melanoma-skin-cancer/incidence
The number of new melanoma skin cancer cases on average each year in the UK is projected to rise from around 20,800 cases in 2023-2025 to around 26,500 cases in 2038-2040. […] Melanoma skin cancer incidence rates are projected to rise by 9% in the UK between 2023-2025 and 2038-2040, to 33 cases per 100,000 people on average each year by 2038-2040. […] An estimated 110,300 people who had been diagnosed with melanoma skin cancer between 1991 and 2010 were alive in the UK at the end of 2010.
- #1 Changing trends in the disease burden of non-melanoma skin cancer globally from 1990 to 2019 and its predicted level in 25âyears | BMC Cancer | Full Texthttps://bmccancer.biomedcentral.com/articles/10.1186/s12885-022-09940-3
The disease burden will continue to increase or remain relatively stable at high levels in the future. […] The number of new cases attributable to NMSC was 6,353,687 in 2019, the number of deaths was 56,054, and the number of DALYs was 1,183,233. […] The number of new cases attributable to NMSC increased from 1,951,299 in 1990 to 6,353,687 in 2019, and the number of deaths of NMSC increased from 23,222 to 56,054 between 1990 and 2019. […] The BAPC model predicts that the ASIR attributable to NMSC will increase slightly for both sexes over the next 25 years, but the ASMR and the age-standardized DALYs rate will decrease. […] This study comprehensively assesses and predicts the global NMSC-related disease burden and makes notable discoveries. […] NMSC appears to be directly related to skin types in Caucasians. […] We find that the NMSC-related disease burden varies in different GBD regions. […] This study shows that NMSC poses a substantial global disease burden and predicts that the future disease burden of NMSC will remain severe.
- #1 The epidemiology of skin cancer at Dr. Cipto Mangunkusumo National Central General Hospital from 2014 to 2017https://scholarhub.ui.ac.id/jdvi/vol4/iss1/3/
The incidence of skin cancer has been increasing over the past decades globally. […] The purpose of this study is to evaluate the increment of skin cancer cases at Dr. Cipto Mangunkusumo National General Hospital, Jakarta. […] From 263 skin cancer cases, the most frequent skin cancer was basal cell carcinoma (BCC; 66.9%), followed by squamous cell carcinoma (SCC; 27.4%), and malignant melanoma (MM; 5.7%). […] In comparison with other types, the incidence of BCC in Dr. Cipto Mangunkusumo National General Hospital is increasing. […] A well-documented skin cancer registry is required to establish national data of skin cancer in Indonesia.
- #1 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
Because exposure to UV light is the most preventable risk factor for all skin cancers, the American Academy of Dermatology encourages everyone to stay out of indoor tanning beds and protect their skin outdoors by seeking shade, wearing protective clothing including a long-sleeved shirt, pants, a wide-brimmed hat and sunglasses with UV protection and applying a broad-spectrum, water-resistant sunscreen with an SPF of 30 or higher to all skin not covered by clothing. (26-28,44) […] Skin cancer warning signs include changes in size, shape, or color of a mole or other skin lesion, the appearance of a new growth on the skin, or a sore that doesn’t heal. If you notice any spots on your skin that are different from the others, or anything changing, itching or bleeding, the American Academy of Dermatology recommends that you make an appointment with a board-certified dermatologist.
- #1 Epidemiology of Keratinocyte Skin Cancer with a Focus on Cutaneous Squamous Cell Carcinomahttps://www.mdpi.com/2072-6694/16/3/606
Epidemiology of Keratinocyte Skin Cancer with a Focus on Cutaneous Squamous Cell Carcinoma […] The incidence of keratinocyte skin cancer has rapidly been increasing over the last five decades in fair skinned populations throughout the world. About 20% account for squamous cell carcinoma (SCC), and mainly the elderly are affected. Although the mortality rate is low, keratinocyte skin cancer is associated with a high morbidity, especially if multiple tumors occur, and pose a problem for the healthcare system. Here, we present the epidemiology of keratinocyte skin cancer, with a focus on SCC in Queensland, Australia; the United States and the north of Europe, and give an outlook to further challenges. […] Keratinocyte skin cancer, consisting of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), is by far the most common cancer in white-skinned populations, with rapid increases over the last 50 years. While the age-standardized incidence rates increase worldwide, the age-standardized mortality rates are variable. The incidence rates of keratinocyte skin cancer are much higher compared to those of melanoma, and are largely attributed to the raising exposure to ultraviolet (UV) radiation, the most important causal risk factor for skin cancer. […] Although mortality rates are relatively low, SCC is an increasing problem for healthcare services, significantly causing morbidity, especially in older age groups. This review reports on the epidemiology of keratinocyte skin cancer, with a focus on SCC, in Australia, the United States, and the north of Europe, with an outlook on further challenges health systems will be confronted with in the next 20 years.
- #2 Skin Cancer Facts & Statisticshttps://www.skincancer.org/skin-cancer-information/skin-cancer-facts/
Get the facts about skin cancer, the most common cancer in the United States and worldwide. […] In the U.S., more than 9,500 people are diagnosed with skin cancer every day. More than two people die of the disease every hour. […] More people are diagnosed with skin cancer each year in the U.S. than all other cancers combined. […] At least one in five Americans will develop skin cancer by the age of 70. […] The diagnosis and treatment of nonmelanoma skin cancers in the U.S. increased by 77 percent between 1994 and 2014. […] About 90 percent of nonmelanoma skin cancers are associated with exposure to ultraviolet (UV) radiation from the sun. […] Basal cell carcinoma (BCC) is the most common form of skin cancer. An estimated 3.6 million cases of BCC are diagnosed in the U.S. each year.
- #2 Epidemiology of Keratinocyte Skin Cancer with a Focus on Cutaneous Squamous Cell Carcinomahttps://www.mdpi.com/2072-6694/16/3/606
Nonmelanoma skin cancer is currently the most common malignant neoplasm in white populations and thus in Germany as well. On the other hand, it is rare in African and Asian populations because these populations have strong protection by pigments. Nonmelanoma skin cancer mainly consists of keratinocyte skin cancer, with about 80% basal cell carcinoma (BCC) and about 20% squamous cell carcinoma (SCC), which originate from keratinocytes. […] In white populations, all skin cancers are predominantly caused due to ultraviolet (UV) radiation. This means that they could be largely prevented through behavioral modification and avoidance of UV exposure. […] The incidence of nonmelanoma skin cancer is far higher than that of any other skin cancer. In Germany, the incidence of nonmelanoma skin cancer is about tenfold-increased compared to melanoma. […] However, the mortality rate is very low. For this reason, nonmelanoma skin cancer is usually not recorded by cancer registries worldwide, and others report only the first tumor.
- #2 Epidemiology, prevention, screening and surveillance of NMSChttps://oncologypro.esmo.org/education-library/esmo-books/essentials-for-clinicians/melanoma-other-skin-cancers/epidemiology-prevention-screening-and-surveillance-of-nmsc
NMSCs make up the greatest proportion of all human cancers, with an incidence of 8% worldwide. […] Common NMSCs comprise basal cell carcinoma (BCC) arising from basal cells: 57%-80% of all NMSCs, and cutaneous squamous cell carcinoma (cSCC) arising from epidermal keratinocytes: 20%-25% of all NMSCs. […] BCC and cSCC show a low rate for distant metastases, but a higher risk for local recurrence. Major risk factors are chronic sun-damaged skin and immunosuppression. […] Risk factors for aggressive courses of cSCCs are immunosuppression (e.g. after solid-organ transplantation), high tumour thickness (6 mm), poor differentiation and localisation (e.g. lips, ears). […] BCCs more often arise in males (ratio 2.1:1) and elderly patients; the median age at diagnosis is 67 years. […] Around 80% of all BCCs are located in the head and neck region, followed, more rarely, by the hands. […] cSCCs usually originate from precancerous lesions such as actinic keratosis, but they can also develop de novo. […] High-risk patients should be screened regularly with a whole-body examination, e.g. at 3-month intervals after organ transplantation or after previous high-risk NMSC.
- #2 Melanoma; Epidemiology, prevention, screening and surveillancehttps://oncologypro.esmo.org/education-library/esmo-books/essentials-for-clinicians/melanoma-other-skin-cancers/chap-1-epidemiology-prevention-screening-and-surveillance
Although cuMM represents only 4% of all skin cancers (including NMSC), it is responsible for 80% of all skin cancer deaths. […] Survival for melanoma patients with metastases is significantly prolonged by new therapeutic options compared with chemotherapy. […] Melanoma-specific survival of MM depends on the stage at initial diagnosis, comprising primary tumour characteristics, and local and distant metastasis status.
- #2 Skin cancer statistics | World Cancer Research Fundhttps://www.wcrf.org/preventing-cancer/cancer-statistics/skin-cancer-statistics/
Skin cancer is the 17th most common cancer worldwide. It is the 14th most common cancer in men and the 14th most common cancer in women. […] There were 331,722 new cases of skin cancer in 2022. The US, Germany and the UK had the highest number of skin cancer cases in 2022. […] The US, China and Russia had the highest number of deaths from skin cancer in 2022.
- #2 Epidemiology of Skin Cancer in 2024 | IntechOpenhttps://www.intechopen.com/chapters/1195964
Incidence and mortality rates varied significantly by country and region, with the highest incidence found in light-skinned populations in North America, western and northern Europe (including Denmark, Norway, and the Netherlands), and Australia/New Zealand. […] With increasing incidence rates in all age categories and geographical areas, skin cancer is still a major worldwide health issue in 2024. […] The epidemiological trends for melanoma and non-melanoma skin cancers have been described in this chapter, with special emphasis on the intricate interactions between socioeconomic, environmental, and genetic factors that affect risk. […] Reducing the worldwide incidence of skin cancer and enhancing patient outcomes require sustained investment in preventive measures, enhanced diagnostic technologies, and fair access to therapy.
- #2 Epidemiology of Skin Cancer in 2024 | IntechOpenhttps://www.intechopen.com/chapters/1195964
Australia and New Zealand have the highest reported rates of NMSC in the world, with Australia recording an incidence of over 1000 cases per 100,000 people per year. […] In Asia, the incidence of NMSC is generally lower than in Western countries, though it is on the rise in some regions. […] NMSC incidence in Africa is lower than in regions with predominantly lighter-skinned populations, although the data are limited. […] Skin malignancies are the most frequently diagnosed type of cancer worldwide, with an expected 1.5 million new cases since 2020. […] Over the past 50 years, melanoma incidence rates have been increasing in people of European descent with fair phenotypes. […] More than three-quarters of all newly diagnosed melanoma cases can be linked to UV radiation, making populations susceptible to this strong and widespread risk factor for the disease largely responsible for this increase.
- #2 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
Skin cancer is the most common cancer in the United States. (1,2) […] Current estimates are that one in five Americans will develop skin cancer in their lifetime. (3) […] It is estimated that approximately 9,500 people in the U.S. are diagnosed with skin cancer every day. (4-6) […] It is estimated that the overall incidence of BCC increased by 145% between 1976-1984 and 2000-2010, and the overall incidence of SCC increased 263% over that same period. (7) […] More than 1 million Americans are living with melanoma. (8) […] It is estimated that 212,200 new cases of melanoma, 107,240 noninvasive (in situ) and 104,960 invasive, will be diagnosed in the U.S. in 2025. (6) […] Melanoma rates in the United States have been rising rapidly over the past 30 years doubling from 1982 to 2011 but trends within the past decade vary by age. (1,6,10) There has been a 31.5% increase between 2011 and 2019. (11)
- #2 Melanoma Skin Cancer Statistics | American Cancer Societyhttps://www.cancer.org/cancer/types/melanoma-skin-cancer/about/key-statistics.html
Cancer of the skin is by far the most common of all cancers in the United States. Melanoma accounts for only about 1% of skin cancers but causes a large majority of skin cancer deaths. […] The American Cancer Societys estimates for melanoma in the United States for 2025 are: About 104,960 new melanomas will be diagnosed (about 60,550 in men and 44,410 in women). About 8,430 people are expected to die of melanoma (about 5,470 men and 2,960 women). […] Melanoma death rates declined rapidly from 2013 to 2022, largely because of advances in treatment. […] The risk of melanoma increases as people age. The average age of people when it is diagnosed is 66. But melanoma is not uncommon even among those younger than 30. In fact, its one of the most common cancers in young adults (especially young women).
- #2 Melanoma of the Skin Statistics | Skin Cancer | CDChttps://www.cdc.gov/skin-cancer/statistics/index.html
Skin cancer is the most common form of cancer in the United States. […] Central cancer registries collect data on melanoma of the skin and nonepithelial skin cancers such as Merkel cell carcinoma. […] Data on basal cell and squamous cell carcinomas, the most common types of skin cancer, are not normally collected by central cancer registries. […] An examination of Medical Expenditure Panel Survey data suggests that each year, about 6.1 million adults are treated for basal cell and squamous cell carcinomas at a cost of about $8.9 billion. […] The Melanoma Dashboard provides state and local data to help communities address their unique melanoma prevention needs. […] National survey data about sun protection, indoor tanning, and sunburn are collected through the Youth Risk Behavior Surveillance System (for high school students) and the National Health Interview Survey (for adults aged 18 or older).
- #2 Melanoma; Epidemiology, prevention, screening and surveillancehttps://oncologypro.esmo.org/education-library/esmo-books/essentials-for-clinicians/melanoma-other-skin-cancers/chap-1-epidemiology-prevention-screening-and-surveillance
Malignant melanoma (MM) arises from melanocytes responsible for pigmentation, which are located in the skin, mucosa, central nervous system or uveal tract of the eye. […] Worldwide, cutaneous MM (cuMM) comprises 1.7% cases of all newly diagnosed primary malignant cancers (excluding non-melanoma skin cancer [NMSC]). […] Incidence and mortality vary substantially between continents with low incidences in Asia and the highest incidences in Australia. […] In Europe the overall incidence of cuMM is rising rapidly with highest rates in northern and north-western countries such as the UK, Ireland and the Netherlands, and lowest rates in Portugal and Spain. […] Currently, cuMM is the sixth most common tumour in men and women in Europe across all malignancies (NMSC included in other cancers).
- #2 Melanoma skin cancer statistics | Cancer Research UKhttps://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/melanoma-skin-cancer
There are around 17,500 new melanoma skin cancer cases in the UK every year, that’s 48 every day (2017-2019). […] Melanoma skin cancer is the 5th most common cancer in the UK, accounting for 5% of all new cancer cases (2017-2019). […] Since the early 1990s, melanoma skin cancer incidence rates have increased by around two-and-a-half times (147%) in the UK. […] Over the last decade, melanoma skin cancer incidence rates have increased by almost a third (31%) in the UK. […] Melanoma skin cancer incidence rates are projected to rise by 9% in the UK between 2023-2025 and 2038-2040. […] Melanoma skin cancer mortality rates are projected to fall by 12% in the UK between 2023-2025 and 2038-2040. […] Almost 9 in 10 (87.4%) people diagnosed with melanoma skin cancer in England survive their disease for ten years or more, it is predicted (2013-2017). […] Melanoma skin cancer survival has doubled in the last 50 years in the UK. […] 86% of melanoma skin cancer cases in the UK are preventable.
- #2 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
Excess exposure to UV radiation from sunlight or use of indoor tanning also increases risk for all skin cancer types, as does a personal history of the disease. (6) […] The majority of melanoma cases are attributable to UV exposure. (25-28) […] Research suggests that regular sunscreen use may reduce risk of melanoma. (28-31) […] Risk factors for all types of skin cancer include skin that burns easily; blonde or red hair; a history of excessive sun exposure, including sunburns; tanning bed use; a weakened immune system; and a history of skin cancer. (6) […] Melanoma survivors have an approximately eight-fold increased risk of developing another melanoma compared to the general population. (40) […] Men and women with a history of nonmelanoma skin cancer are at a higher risk of developing melanoma than people without a nonmelanoma skin cancer history. (41,42)
- #2 Epidemiology of skin cancer – PubMedhttps://pubmed.ncbi.nlm.nih.gov/25207363/
Melanoma and nonmelanoma skin cancer (NMSC) are now the most common types of cancer in white populations. […] Both tumor entities show an increasing incidence rate worldwide but a stable or decreasing mortality rate. […] NMSC is the most common cancer in white-skinned individuals with a worldwide increasing incidence. […] The rising incidence rates of NMSC are probably caused by a combination of increased exposure to ultraviolet (UV) or sun light, increased outdoor activities, changes in clothing style, increased longevity, ozone depletion, genetics and in some cases, immune suppression. […] Cutaneous melanoma is the most rapidly increasing cancer in white populations, in the last 3 decades incidence rates have risen up to 5-fold. […] Changes in outdoor activities and exposure to sunlight during the past 50 years are an important factor for the increasing incidence of melanoma.
- #2 Skin Cancer Facts & Statisticshttps://www.skincancer.org/skin-cancer-information/skin-cancer-facts/
Those who have ever tanned indoors have an 83 percent increased risk of developing squamous cell carcinoma and a 29 percent increased risk of developing basal cell carcinoma. […] Women who have ever tanned indoors are six times more likely to be diagnosed with melanoma in their 20s than those who have never tanned indoors. […] Melanoma in children and adolescents accounts for a tiny percentage of all new melanoma cases in the United States, with about 300 cases a year in children under 20 years old.
- #2 Risk factors/epidemiology | National Cancer Prevention Policy Skin Cancer Statistics and Issues | Cancer Councilhttps://www.cancer.org.au/about-us/policy-and-advocacy/prevention/uv-radiation/related-resources/risk-factors-epidemiology
Those with fair skin possess little epidermal eumelanin, which absorbs UV radiation and acts to neutralise UV radiation-generated free radicals, and are thus at greater risk of skin cancer. […] However, it is the high pheomelanin to eumelanin ratio in the melanin of individuals with a red-hair and fair skin phenotype that greatly increases their melanoma risk. […] In Australia, up to 95% of melanomas are attributable to overexposure to UV radiation. […] Skin exposure to UV radiation can result in DNA damage and mutations. […] UV radiation is classified as a complete carcinogen because it causes mutations as well as general damage, and inducts and promotes tumour growth. […] Excessive UV exposure increases the risk of both melanoma and keratinocytic skin cancers. […] Melanoma risk is associated with cumulative, intermittent exposure to UV radiation.
- #2 Melanoma skin cancer incidence statistics | Cancer Research UKhttps://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/melanoma-skin-cancer/incidence
In the UK in 2017-2019, on average each year more than a quarter of new cases (29%) were in people aged 75 and over. […] Age-specific incidence rates rise more steeply for females from age 20-24, but more steeply for males from age 55-59, then drop in the oldest age group. […] The highest rates are in the 85 to 89 age group for females and males. […] Incidence rates are significantly higher for females than males in the younger age groups and significantly lower for females than males in the older age groups. […] For melanoma skin cancer, like most cancer types, incidence increases with age. This largely reflects cell DNA damage accumulating over time. […] Melanoma skin cancer European age-standardised (AS) incidence rates for females and males combined increased by 147% in the UK between 1993-1995 and 2017-2019.
- #2 Epidemiology of Skin Cancer in 2024 | IntechOpenhttps://www.intechopen.com/chapters/1195964
This chapter will also cover current epidemiological trends, such as the rising prevalence of melanoma in younger people, especially in areas with high UV exposure, and inequalities in healthcare access that impact diagnostic and treatment results. […] Understanding the global epidemiology of NMSC is crucial for public health efforts aimed at prevention and management. […] NMSC is the most frequently diagnosed cancer globally, with an increasing incidence in both developed and developing nations. […] In North America, particularly the United States and Canada, NMSC incidence is notably high. […] NMSC rates have increased significantly over the last several decades, with studies showing that the incidence of BCC has risen by 145% and SCC by 263% between the 1970s and the 2010s. […] In Europe, NMSC is also one of the most commonly diagnosed cancers, though incidence varies by region.
- #2 Melanoma of the Skin â Cancer Stat Factshttps://seer.cancer.gov/statfacts/html/melan.html
Estimated New Cases in 2025 104,960. […] Estimated Deaths in 2025 8,430. […] Melanoma of the skin represents 5.1% of all new cancer cases in the U.S. […] In 2025, it is estimated that there will be 104,960 new cases of melanoma of the skin and an estimated 8,430 people will die of this disease. […] The rate of new cases of melanoma of the skin was 21.9 per 100,000 men and women per year based on 2018â2022 cases, age-adjusted. […] For melanoma of the skin, death rates are higher among the middle-aged and elderly. The death rate was 2.0 per 100,000 men and women per year based on 2019â2023 deaths, age-adjusted. […] Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments. […] Using statistical models for analysis, age-adjusted rates for new melanoma of the skin cases have been rising on average 1.2% each year over 2013â2022. Age-adjusted death rates have been falling on average 2.8% each year over 2014â2023.
- #2 Epidemiology of Skin Cancer: Update 2019 – PubMedhttps://pubmed.ncbi.nlm.nih.gov/32918216/
Mortality rates of melanoma show stabilization in the USA, Australia, and in European countries. […] Among younger cohorts in some populations (e.g., Australia and New Zealand), stabilizing or declining incidence rates of CM are observed, potentially caused by primary prevention campaigns aimed at reducing UV exposure. […] In contrast, incidence rates of CM are still rising in most European countries and in the USA. Ongoing trends towards thinner melanoma are largely ascribed to earlier detection.
- #2 Epidemiology of Skin Cancer: Update 2019 – PubMedhttps://pubmed.ncbi.nlm.nih.gov/32918216/
Melanoma and keratinocyte skin cancer (KSC) are the most common types of cancer in White-skinned populations. Both tumor entities showed increasing incidence rates worldwide but stable or decreasing mortality rates. Rising incidence rates of cutaneous melanoma (CM) and KSC are largely attributed to increasing exposure to ultraviolet (UV) radiation, the main causal risk factor for skin cancer. […] Incidence rates of KSC, comprising of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are much higher than that of melanoma. […] Cutaneous melanoma is rapidly increasing in White populations, with an estimated annual increase of around 3-7% over the past decades. […] Changes in outdoor activities and exposure to sunlight during the past 70 years are an important factor for the increasing incidence of melanoma.
- #2 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
The incidence of melanoma among non-Hispanic White individuals is almost 30 times higher than that among non-Hispanic Black or Asian/Pacific Islander individuals. (12,13) […] Skin cancer in patients with darker skin tones is often diagnosed in its later stages, when its more difficult to treat. (16-20) […] Research has shown that patients with darker skin tones are less likely than patients with lighter skin tones to survive melanoma. (18-21) […] The vast majority of skin cancer deaths are from melanoma. (6) […] Nearly 20 Americans die from melanoma every day. In 2025, it is estimated that 8,430 deaths will be attributed to melanoma 5,470 men and 2,960 women. (6) […] Research indicates that men with melanoma generally have lower survival rates than women with melanoma. (6,8,24) […] Overall melanoma death rates drastically declined from 2014 through 2022 by nearly 4%. (6)
- #2 Skin Cancer Facts & Statisticshttps://www.skincancer.org/skin-cancer-information/skin-cancer-facts/
Squamous cell carcinoma (SCC) is the second most common form of skin cancer. Approximately 1.8 million cases of SCC are diagnosed in the U.S. each year. […] The vast majority of melanomas are caused by the sun. In fact, one UK study found that about 86 percent of melanomas can be attributed to exposure to ultraviolet (UV) radiation from the sun. […] Data from 2014 â 2020 shows that across all stages of melanoma, the average five-year survival rate in the U.S. is 94 percent. The estimated five-year survival rate for patients whose melanoma is detected early is over 99 percent. […] Indoor tanning devices can emit UV radiation in amounts 10 to 15 times higher than the sun at its peak intensity. […] More than 419,000 cases of skin cancer in the U.S. each year are linked to indoor tanning, including about 245,000 basal cell carcinomas, 168,000 squamous cell carcinomas and 6,200 melanomas.
- #2 Incidence and mortality | National Cancer Prevention Policy Skin Cancer Statistics and Issues | Cancer Councilhttps://www.cancer.org.au/about-us/policy-and-advocacy/prevention/uv-radiation/related-resources/skin-cancer-incidence-and-mortality
Melanoma of the skin is the third most commonly diagnosed cancer in Australia (excluding NMSC). […] In 2019, 15,628 new cases of melanoma were diagnosed in Australia, and in 2021, 1,455 people died. […] In Australia, the age-standardised incidence rate for melanoma increased by 120% between 1982 and 2019, from 29.6 cases per 100,000 persons to 65 cases per 100,000 persons. […] However, how much of this increase is due to a real increase in the underlying disease, and how much is due to improved detection methods, is unknown. […] In 2012-2016, the incidence of melanoma was 16.2 cases per 100,000 among Indigenous Australians, compared with 39.7 cases per 100,000 among non-Indigenous Australians. […] Mortality rates were also lower for Indigenous Australians (2.2 deaths per 100,000) compared with non-Indigenous Australians (5.1 deaths per 100,000).
- #2 Basal cell carcinoma: Epidemiology – Journal of Skin and Sexually Transmitted Diseaseshttps://jsstd.org/basal-cell-carcinoma-epidemiology/
Basal cell carcinoma is the most common skin cancer in white skinned individuals with a rising incidence observed worldwide. […] Recent years have seen a rise in the incidence of both SCC and BCC. This increase is more pronounced for SCC. […] A systematic review that analyzed the data from 38 different countries worldwide over the period 1955-2007 found the highest annual incidence rate for BCC in Australia (1000/100,000 person-years) and the lowest rates in parts of Africa (1/100,000 person-years). […] A population-based study in Olmsted County, Minnesota (2000-2010) recorded the incidence of BCC as 360/100,000 persons for men and 292.9 for women. […] European age-standardized incidence rate for BCC as documented in United Kingdom in 2013-2015 was 285/100,000 person-years. […] Non-melanoma skin cancers are rare in Asians, probably due to the protective effect of melanin against the deleterious effects of UV light.
- #2 Basal cell carcinoma: Epidemiology – Journal of Skin and Sexually Transmitted Diseaseshttps://jsstd.org/basal-cell-carcinoma-epidemiology/
Incidence rate of BCC in colored skin ranged from 1.5 to 15.57/100,000 population in previous studies. […] Various Indian studies have reported SCC to be more frequent than BCC, which were consistent with the findings in other dark skinned populations. […] A study from Singapore noted age-standardized incidence rates of 6.9, 2.6, and 1.4/100,000 person-years for BCC among the Chinese, Malays, and Indians, respectively, in 2016. […] The same study found that the age-standardized incidence rates for BCC were 2.7, 1.2, and 0.5 tumors/100,000 person-years, respectively, among the Chinese, Malays, and Indians in 1968, showing a clear increase in incidence, which was more pronounced for the Chinese. […] The following section focuses on the risk factors for BCC. […] Sunlight, predominantly UVB is considered as the most important risk factor for BCC and the risk correlates with the amount and nature of accumulated exposure.
- #2 Skin Cancer Surveillance Strategies: Digital Applications, Self-examination, and More.https://dermnetnz.org/topics/skin-cancer-and-self-exams
Melanomas are notoriously difficult to discover and diagnose. […] Melanoma survival rates are dramatically improved if a melanoma is detected early, especially when the malignant cells are confined to the tissue of origin called melanoma in situ or level 1 melanoma. […] For these reasons, it is recommended that any concerning lesion is presented to the appropriate physician as soon as possible. […] It is recommended that each person is to look out for changes to their skins appearance through skin self-examination. […] Changes in asymptomatic (atypical) moles and the appearance of any new lesions on the skin for those over 35 years of age are warning signs that should not be ignored. […] Given the difficulties identified here, there is a concern that patients may not have sufficient awareness of their skins appearance and so may only catch any suspicious skin changes at a belated stage.
- #2 Skin Cancer Surveillance Strategies: Digital Applications, Self-examination, and More.https://dermnetnz.org/topics/skin-cancer-and-self-exams
Thorough total-body skin self-examinations, ideally assisted by a partner, should be more prevalent in consumers minds. […] Given the need to closely inspect for changes to the skin, photographic skin surveillance, such as digital dermoscopy of individual lesions and full-body photography, have emerged and are now recommended. […] The more skin that can be recorded with photography, the higher the likelihood of catching any future skin change at an early stage. […] The Melanoma Institute Australia actively recommends the use of photos in the skin self-examination process: The best way to monitor changes on your skin is by taking photographs every few months and comparing them to identify any changes. […] However, there are a few challenges that should be addressed: Cost: clinical photography does come at a cost given the requirement of clinical equipment and personnel.
- #2 Skin surveillance saves lives from melanoma – Melanoma Institute Australiahttps://melanoma.org.au/news/skin-surveillance-saves-lives-from-melanoma/
Current Australian guidelines recommend that individuals at very high risk of melanoma receive full skin examinations every 6 months. However, melanoma screening programs for the general population are not currently undertaken in Australia because of inadequate evidence that melanoma screening ultimately saves lives, uncertainty about overdiagnosis and unnecessary biopsy, and limited evidence that it is cost effective. […] We found that melanoma detection during a routine skin check was associated with lower risk of dying from any cause, but it was not statistically significant for melanoma-specific mortality, said cancer epidemiologist and lead author Prof Anne Cust, from Melanoma Institute Australia, The Daffodil Centre and The University of Sydney. Based on our early findings, the cost-effectiveness of a population melanoma screening program should be re-assessed, and a large randomised controlled trial is needed to provide definitive evidence.
- #2 Incidence and mortality | National Cancer Prevention Policy Skin Cancer Statistics and Issues | Cancer Councilhttps://www.cancer.org.au/about-us/policy-and-advocacy/prevention/uv-radiation/related-resources/skin-cancer-incidence-and-mortality
Although NMSC is the most common cancer type in Australia, it is often reported that breast cancer is the most common cancer in women and prostate cancer is the most common in men. […] Despite the high incidence rate of NMSC, the age-standardised mortality rates are relatively low at 4.8 deaths per 100,000 population for males and 1.7 deaths per 100,000 for females in 2021. […] Skin cancer cost the Australian Health System more than $1.72 billion (including diagnosis, treatment and pathology) in 2019/20. […] In Australia, relative survival after diagnosis of melanoma of the skin is very high when compared with other types of cancer.
- #2 Skin cancer epidemiology | Videncenter for Hudkræfthttps://vfhk.org/en/article/skin-cancer-epidemiology
Did you know that skin cancer is the most common type of all cancers, affecting some 30% of fair-skinned individuals? […] Each year, 15,000 new skin cancer cases are reported in Denmark. The vast majority of these cases are basal cell carcinomas. […] Over the past 25 years, the incidence of skin cancer has increased considerably, and the negative trend is expected to continue for years to come. […] Studies estimate that 11-25% of the population is affected by actinic keratosis, a premalignant condition occurring in patients with accumulated sun exposure. The condition can progress into squamous cell carcinoma. […] The annual cost of skin cancer treatment and patient control is estimated at more than 19 million Euros. […] Theres a 40% risk of developing new cancer within 2-3 years following the first incidence of skin cancer. […] Our research aims to find new and better options for preventing, diagnosing, and treating skin cancer.
- #2 What CDC Is Doing About Skin Cancer | Skin Cancer | CDChttps://www.cdc.gov/skin-cancer/what-cdc-is-doing/index.html
CDC leads efforts to reduce illness and death caused by skin cancer, the most common form of cancer in the United States. […] The Melanoma Dashboard was created in partnership with CDC’s Environmental Public Health Tracking Program to help communities address their unique melanoma prevention needs. It provides state- and county-level data on melanoma incidence, melanoma mortality, and UV irradiance. […] A study looked at the cost of skin cancer treatment in the United States. During 2016 to 2018, more than 6 million adults were treated for skin cancer each year. The overall estimated annual costs were nearly $9 billion. […] Two studies used national data to examine indoor tanning and found that indoor tanning is declining in the United States among both high school students and adults. However, nearly 900,000 high school students and 8 million adults still tan each year.
- #2 Risk factors/epidemiology | National Cancer Prevention Policy Skin Cancer Statistics and Issues | Cancer Councilhttps://www.cancer.org.au/about-us/policy-and-advocacy/prevention/uv-radiation/related-resources/risk-factors-epidemiology
High sun exposure in the first 10 years of life more than doubles melanoma risk, while intense, intermittent sun exposure (number of sunburns and sunbathing vacations) during each decade up to 29 years of age increases risk of melanoma by more than one-and-a-half times. […] A systematic review has shown a dose-response relationship between sunbed use and melanoma risk. […] It is estimated that around 200 melanomas and 34,000 keratinocytic skin cancers per year are caused by occupational exposures in Australia. […] Outdoor workers receive between five to ten times the annual dose of UV than indoor workers. […] A prospective study by Ferrone and colleagues estimated the cumulative five-year risk of a second primary tumour for patients diagnosed with a primary melanoma is 11%, with almost half that risk within the first year. […] Risk of a second primary melanoma increased to 19% for patients with a family history of melanoma, and 24% for patients with dysplastic naevi.
- #2 Epidemiology of Keratinocyte Skin Cancer with a Focus on Cutaneous Squamous Cell Carcinomahttps://www.mdpi.com/2072-6694/16/3/606
Nonmelanoma skin cancer is usually not recorded by cancer registries worldwide. […] A recent study demonstrated that due to changes in registration procedures such as the introduction of an automatic linkage system and especially the inclusion of multiple SCCs, the incidence rates of cutaneous SCC have increased significantly in the Netherlands since 2017. […] Although not recorded or presented in many cancer registries, most patients develop multiple cutaneous SCCs in further course. […] The number of skin cancer patients is likely to increase in the future due to demographic developments and climate-related changes in UV exposure. […] Primary prevention is still inadequate and needs to be improved to prevent further increases in the incidence of cutaneous SCC. […] The incidence of cutaneous SCC is expected to increase by 10 to 75% over the next 20 years. […] Keratinocyte skin cancer is the most common type of cancer in white populations, with SCC accounting for about 20% of keratinocyte skin cancers. […] In western Europe, Australia, and the United States, a further increase in incidence is expected in the coming years.
- #2 Melanoma skin cancer incidence statistics | Cancer Research UKhttps://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/melanoma-skin-cancer/incidence
The number of new melanoma skin cancer cases on average each year in the UK is projected to rise from around 20,800 cases in 2023-2025 to around 26,500 cases in 2038-2040. […] Melanoma skin cancer incidence rates are projected to rise by 9% in the UK between 2023-2025 and 2038-2040, to 33 cases per 100,000 people on average each year by 2038-2040. […] An estimated 110,300 people who had been diagnosed with melanoma skin cancer between 1991 and 2010 were alive in the UK at the end of 2010.
- #2 Epidemiology of Skin Cancer | SpringerLinkhttps://link.springer.com/chapter/10.1007/978-1-4939-0437-2_7
Melanoma and nonmelanoma skin cancer (NMSC) are now the most common types of cancer in white populations. […] NMSC is the most common cancer in white-skinned individuals with a worldwide increasing incidence. […] The rising incidence rates of NMSC are probably caused by a combination of increased exposure to ultraviolet (UV) or sun light, increased outdoor activities, changes in clothing style, increased longevity, ozone depletion, genetics and in some cases, immune suppression. […] Cutaneous melanoma is the most rapidly increasing cancer in white populations, in the last 3 decades incidence rates have risen up to 5-fold. […] Changes in outdoor activities and exposure to sunlight during the past 50 years are an important factor for the increasing incidence of melanoma. […] Mortality rates of melanoma show a stabilization in the USA, Australia and also in European countries. […] However, the impact of primary prevention measures on incidence rates of melanoma is unlikely to be seen in the near future, rather increasing incidence rates to 40-50/100,000 inhabitants/year should be expected in Europe in the next decades.
- #2 Basal cell carcinoma: Epidemiology – Journal of Skin and Sexually Transmitted Diseaseshttps://jsstd.org/basal-cell-carcinoma-epidemiology/
The use of tanning beds is documented as a risk factor for skin cancers, more so for BCC. […] Advancing age is an independent risk factor for BCC with a doubling in incidence from 40 to 70 years. […] The gender predilection varied in different studies. […] Many Indian studies have noted a female preponderance. […] A female predilection is noted for BCC among African Americans also. […] An early-onset (in childhood) BCC is associated with genetic diseases such as basal cell nevus syndrome, xeroderma pigmentosum, nevus sebaceous, and epidermodysplasia verruciformis. […] Incidence of BCC among organ transplant recipients is documented to be about 7-16 times higher than the same in general population. […] With the rising trend noted in BCC, we are expected to see more cases in the coming years. […] The strong association noted between sun exposure and BCC indicates the importance of educating the public regarding the potential risk factors and the measures to avoid them.
- #2 Changing trends in the disease burden of non-melanoma skin cancer globally from 1990 to 2019 and its predicted level in 25âyears | BMC Cancer | Full Texthttps://bmccancer.biomedcentral.com/articles/10.1186/s12885-022-09940-3
The disease burden will continue to increase or remain relatively stable at high levels in the future. […] The number of new cases attributable to NMSC was 6,353,687 in 2019, the number of deaths was 56,054, and the number of DALYs was 1,183,233. […] The number of new cases attributable to NMSC increased from 1,951,299 in 1990 to 6,353,687 in 2019, and the number of deaths of NMSC increased from 23,222 to 56,054 between 1990 and 2019. […] The BAPC model predicts that the ASIR attributable to NMSC will increase slightly for both sexes over the next 25 years, but the ASMR and the age-standardized DALYs rate will decrease. […] This study comprehensively assesses and predicts the global NMSC-related disease burden and makes notable discoveries. […] NMSC appears to be directly related to skin types in Caucasians. […] We find that the NMSC-related disease burden varies in different GBD regions. […] This study shows that NMSC poses a substantial global disease burden and predicts that the future disease burden of NMSC will remain severe.
- #3 Skin Cancer Facts & Statisticshttps://www.skincancer.org/skin-cancer-information/skin-cancer-facts/
Get the facts about skin cancer, the most common cancer in the United States and worldwide. […] In the U.S., more than 9,500 people are diagnosed with skin cancer every day. More than two people die of the disease every hour. […] More people are diagnosed with skin cancer each year in the U.S. than all other cancers combined. […] At least one in five Americans will develop skin cancer by the age of 70. […] The diagnosis and treatment of nonmelanoma skin cancers in the U.S. increased by 77 percent between 1994 and 2014. […] About 90 percent of nonmelanoma skin cancers are associated with exposure to ultraviolet (UV) radiation from the sun. […] Basal cell carcinoma (BCC) is the most common form of skin cancer. An estimated 3.6 million cases of BCC are diagnosed in the U.S. each year.
- #3 Basal cell carcinoma: Epidemiology – Journal of Skin and Sexually Transmitted Diseaseshttps://jsstd.org/basal-cell-carcinoma-epidemiology/
Basal cell carcinoma is the most common skin cancer in white skinned individuals with a rising incidence observed worldwide. […] Recent years have seen a rise in the incidence of both SCC and BCC. This increase is more pronounced for SCC. […] A systematic review that analyzed the data from 38 different countries worldwide over the period 1955-2007 found the highest annual incidence rate for BCC in Australia (1000/100,000 person-years) and the lowest rates in parts of Africa (1/100,000 person-years). […] A population-based study in Olmsted County, Minnesota (2000-2010) recorded the incidence of BCC as 360/100,000 persons for men and 292.9 for women. […] European age-standardized incidence rate for BCC as documented in United Kingdom in 2013-2015 was 285/100,000 person-years. […] Non-melanoma skin cancers are rare in Asians, probably due to the protective effect of melanin against the deleterious effects of UV light.
- #3 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
Skin cancer is the most common cancer in the United States. (1,2) […] Current estimates are that one in five Americans will develop skin cancer in their lifetime. (3) […] It is estimated that approximately 9,500 people in the U.S. are diagnosed with skin cancer every day. (4-6) […] It is estimated that the overall incidence of BCC increased by 145% between 1976-1984 and 2000-2010, and the overall incidence of SCC increased 263% over that same period. (7) […] More than 1 million Americans are living with melanoma. (8) […] It is estimated that 212,200 new cases of melanoma, 107,240 noninvasive (in situ) and 104,960 invasive, will be diagnosed in the U.S. in 2025. (6) […] Melanoma rates in the United States have been rising rapidly over the past 30 years doubling from 1982 to 2011 but trends within the past decade vary by age. (1,6,10) There has been a 31.5% increase between 2011 and 2019. (11)
- #3 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
Excess exposure to UV radiation from sunlight or use of indoor tanning also increases risk for all skin cancer types, as does a personal history of the disease. (6) […] The majority of melanoma cases are attributable to UV exposure. (25-28) […] Research suggests that regular sunscreen use may reduce risk of melanoma. (28-31) […] Risk factors for all types of skin cancer include skin that burns easily; blonde or red hair; a history of excessive sun exposure, including sunburns; tanning bed use; a weakened immune system; and a history of skin cancer. (6) […] Melanoma survivors have an approximately eight-fold increased risk of developing another melanoma compared to the general population. (40) […] Men and women with a history of nonmelanoma skin cancer are at a higher risk of developing melanoma than people without a nonmelanoma skin cancer history. (41,42)
- #3 Risk factors/epidemiology | National Cancer Prevention Policy Skin Cancer Statistics and Issues | Cancer Councilhttps://www.cancer.org.au/about-us/policy-and-advocacy/prevention/uv-radiation/related-resources/risk-factors-epidemiology
Those with fair skin possess little epidermal eumelanin, which absorbs UV radiation and acts to neutralise UV radiation-generated free radicals, and are thus at greater risk of skin cancer. […] However, it is the high pheomelanin to eumelanin ratio in the melanin of individuals with a red-hair and fair skin phenotype that greatly increases their melanoma risk. […] In Australia, up to 95% of melanomas are attributable to overexposure to UV radiation. […] Skin exposure to UV radiation can result in DNA damage and mutations. […] UV radiation is classified as a complete carcinogen because it causes mutations as well as general damage, and inducts and promotes tumour growth. […] Excessive UV exposure increases the risk of both melanoma and keratinocytic skin cancers. […] Melanoma risk is associated with cumulative, intermittent exposure to UV radiation.
- #3 Melanoma Skin Cancer Statistics | American Cancer Societyhttps://www.cancer.org/cancer/types/melanoma-skin-cancer/about/key-statistics.html
Cancer of the skin is by far the most common of all cancers in the United States. Melanoma accounts for only about 1% of skin cancers but causes a large majority of skin cancer deaths. […] The American Cancer Societys estimates for melanoma in the United States for 2025 are: About 104,960 new melanomas will be diagnosed (about 60,550 in men and 44,410 in women). About 8,430 people are expected to die of melanoma (about 5,470 men and 2,960 women). […] Melanoma death rates declined rapidly from 2013 to 2022, largely because of advances in treatment. […] The risk of melanoma increases as people age. The average age of people when it is diagnosed is 66. But melanoma is not uncommon even among those younger than 30. In fact, its one of the most common cancers in young adults (especially young women).
- #3 Epidemiology of skin cancer – PubMedhttps://pubmed.ncbi.nlm.nih.gov/25207363/
Melanoma and nonmelanoma skin cancer (NMSC) are now the most common types of cancer in white populations. […] Both tumor entities show an increasing incidence rate worldwide but a stable or decreasing mortality rate. […] NMSC is the most common cancer in white-skinned individuals with a worldwide increasing incidence. […] The rising incidence rates of NMSC are probably caused by a combination of increased exposure to ultraviolet (UV) or sun light, increased outdoor activities, changes in clothing style, increased longevity, ozone depletion, genetics and in some cases, immune suppression. […] Cutaneous melanoma is the most rapidly increasing cancer in white populations, in the last 3 decades incidence rates have risen up to 5-fold. […] Changes in outdoor activities and exposure to sunlight during the past 50 years are an important factor for the increasing incidence of melanoma.
- #3 Melanoma of the Skin â Cancer Stat Factshttps://seer.cancer.gov/statfacts/html/melan.html
Estimated New Cases in 2025 104,960. […] Estimated Deaths in 2025 8,430. […] Melanoma of the skin represents 5.1% of all new cancer cases in the U.S. […] In 2025, it is estimated that there will be 104,960 new cases of melanoma of the skin and an estimated 8,430 people will die of this disease. […] The rate of new cases of melanoma of the skin was 21.9 per 100,000 men and women per year based on 2018â2022 cases, age-adjusted. […] For melanoma of the skin, death rates are higher among the middle-aged and elderly. The death rate was 2.0 per 100,000 men and women per year based on 2019â2023 deaths, age-adjusted. […] Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments. […] Using statistical models for analysis, age-adjusted rates for new melanoma of the skin cases have been rising on average 1.2% each year over 2013â2022. Age-adjusted death rates have been falling on average 2.8% each year over 2014â2023.
- #3 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
The incidence of melanoma among non-Hispanic White individuals is almost 30 times higher than that among non-Hispanic Black or Asian/Pacific Islander individuals. (12,13) […] Skin cancer in patients with darker skin tones is often diagnosed in its later stages, when its more difficult to treat. (16-20) […] Research has shown that patients with darker skin tones are less likely than patients with lighter skin tones to survive melanoma. (18-21) […] The vast majority of skin cancer deaths are from melanoma. (6) […] Nearly 20 Americans die from melanoma every day. In 2025, it is estimated that 8,430 deaths will be attributed to melanoma 5,470 men and 2,960 women. (6) […] Research indicates that men with melanoma generally have lower survival rates than women with melanoma. (6,8,24) […] Overall melanoma death rates drastically declined from 2014 through 2022 by nearly 4%. (6)
- #3 Incidence and mortality | National Cancer Prevention Policy Skin Cancer Statistics and Issues | Cancer Councilhttps://www.cancer.org.au/about-us/policy-and-advocacy/prevention/uv-radiation/related-resources/skin-cancer-incidence-and-mortality
Melanoma of the skin is the third most commonly diagnosed cancer in Australia (excluding NMSC). […] In 2019, 15,628 new cases of melanoma were diagnosed in Australia, and in 2021, 1,455 people died. […] In Australia, the age-standardised incidence rate for melanoma increased by 120% between 1982 and 2019, from 29.6 cases per 100,000 persons to 65 cases per 100,000 persons. […] However, how much of this increase is due to a real increase in the underlying disease, and how much is due to improved detection methods, is unknown. […] In 2012-2016, the incidence of melanoma was 16.2 cases per 100,000 among Indigenous Australians, compared with 39.7 cases per 100,000 among non-Indigenous Australians. […] Mortality rates were also lower for Indigenous Australians (2.2 deaths per 100,000) compared with non-Indigenous Australians (5.1 deaths per 100,000).
- #3 Melanoma of the Skin Statistics | Skin Cancer | CDChttps://www.cdc.gov/skin-cancer/statistics/index.html
Skin cancer is the most common form of cancer in the United States. […] Central cancer registries collect data on melanoma of the skin and nonepithelial skin cancers such as Merkel cell carcinoma. […] Data on basal cell and squamous cell carcinomas, the most common types of skin cancer, are not normally collected by central cancer registries. […] An examination of Medical Expenditure Panel Survey data suggests that each year, about 6.1 million adults are treated for basal cell and squamous cell carcinomas at a cost of about $8.9 billion. […] The Melanoma Dashboard provides state and local data to help communities address their unique melanoma prevention needs. […] National survey data about sun protection, indoor tanning, and sunburn are collected through the Youth Risk Behavior Surveillance System (for high school students) and the National Health Interview Survey (for adults aged 18 or older).
- #3 Skin Cancer Surveillance Strategies: Digital Applications, Self-examination, and More.https://dermnetnz.org/topics/skin-cancer-and-self-exams
Melanomas are notoriously difficult to discover and diagnose. […] Melanoma survival rates are dramatically improved if a melanoma is detected early, especially when the malignant cells are confined to the tissue of origin called melanoma in situ or level 1 melanoma. […] For these reasons, it is recommended that any concerning lesion is presented to the appropriate physician as soon as possible. […] It is recommended that each person is to look out for changes to their skins appearance through skin self-examination. […] Changes in asymptomatic (atypical) moles and the appearance of any new lesions on the skin for those over 35 years of age are warning signs that should not be ignored. […] Given the difficulties identified here, there is a concern that patients may not have sufficient awareness of their skins appearance and so may only catch any suspicious skin changes at a belated stage.
- #3 Epidemiology of Keratinocyte Skin Cancer with a Focus on Cutaneous Squamous Cell Carcinomahttps://www.mdpi.com/2072-6694/16/3/606
Nonmelanoma skin cancer is usually not recorded by cancer registries worldwide. […] A recent study demonstrated that due to changes in registration procedures such as the introduction of an automatic linkage system and especially the inclusion of multiple SCCs, the incidence rates of cutaneous SCC have increased significantly in the Netherlands since 2017. […] Although not recorded or presented in many cancer registries, most patients develop multiple cutaneous SCCs in further course. […] The number of skin cancer patients is likely to increase in the future due to demographic developments and climate-related changes in UV exposure. […] Primary prevention is still inadequate and needs to be improved to prevent further increases in the incidence of cutaneous SCC. […] The incidence of cutaneous SCC is expected to increase by 10 to 75% over the next 20 years. […] Keratinocyte skin cancer is the most common type of cancer in white populations, with SCC accounting for about 20% of keratinocyte skin cancers. […] In western Europe, Australia, and the United States, a further increase in incidence is expected in the coming years.
- #3 Melanoma skin cancer statistics | Cancer Research UKhttps://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/melanoma-skin-cancer
There are around 17,500 new melanoma skin cancer cases in the UK every year, that’s 48 every day (2017-2019). […] Melanoma skin cancer is the 5th most common cancer in the UK, accounting for 5% of all new cancer cases (2017-2019). […] Since the early 1990s, melanoma skin cancer incidence rates have increased by around two-and-a-half times (147%) in the UK. […] Over the last decade, melanoma skin cancer incidence rates have increased by almost a third (31%) in the UK. […] Melanoma skin cancer incidence rates are projected to rise by 9% in the UK between 2023-2025 and 2038-2040. […] Melanoma skin cancer mortality rates are projected to fall by 12% in the UK between 2023-2025 and 2038-2040. […] Almost 9 in 10 (87.4%) people diagnosed with melanoma skin cancer in England survive their disease for ten years or more, it is predicted (2013-2017). […] Melanoma skin cancer survival has doubled in the last 50 years in the UK. […] 86% of melanoma skin cancer cases in the UK are preventable.
- #3 Epidemiology of Skin Cancer in 2024 | IntechOpenhttps://www.intechopen.com/chapters/1195964
Incidence and mortality rates varied significantly by country and region, with the highest incidence found in light-skinned populations in North America, western and northern Europe (including Denmark, Norway, and the Netherlands), and Australia/New Zealand. […] With increasing incidence rates in all age categories and geographical areas, skin cancer is still a major worldwide health issue in 2024. […] The epidemiological trends for melanoma and non-melanoma skin cancers have been described in this chapter, with special emphasis on the intricate interactions between socioeconomic, environmental, and genetic factors that affect risk. […] Reducing the worldwide incidence of skin cancer and enhancing patient outcomes require sustained investment in preventive measures, enhanced diagnostic technologies, and fair access to therapy.
- #4 Basal cell carcinoma: Epidemiology – Journal of Skin and Sexually Transmitted Diseaseshttps://jsstd.org/basal-cell-carcinoma-epidemiology/
Basal cell carcinoma is the most common skin cancer in white skinned individuals with a rising incidence observed worldwide. […] Recent years have seen a rise in the incidence of both SCC and BCC. This increase is more pronounced for SCC. […] A systematic review that analyzed the data from 38 different countries worldwide over the period 1955-2007 found the highest annual incidence rate for BCC in Australia (1000/100,000 person-years) and the lowest rates in parts of Africa (1/100,000 person-years). […] A population-based study in Olmsted County, Minnesota (2000-2010) recorded the incidence of BCC as 360/100,000 persons for men and 292.9 for women. […] European age-standardized incidence rate for BCC as documented in United Kingdom in 2013-2015 was 285/100,000 person-years. […] Non-melanoma skin cancers are rare in Asians, probably due to the protective effect of melanin against the deleterious effects of UV light.
- #4 Skin Cancer Facts & Statisticshttps://www.skincancer.org/skin-cancer-information/skin-cancer-facts/
Get the facts about skin cancer, the most common cancer in the United States and worldwide. […] In the U.S., more than 9,500 people are diagnosed with skin cancer every day. More than two people die of the disease every hour. […] More people are diagnosed with skin cancer each year in the U.S. than all other cancers combined. […] At least one in five Americans will develop skin cancer by the age of 70. […] The diagnosis and treatment of nonmelanoma skin cancers in the U.S. increased by 77 percent between 1994 and 2014. […] About 90 percent of nonmelanoma skin cancers are associated with exposure to ultraviolet (UV) radiation from the sun. […] Basal cell carcinoma (BCC) is the most common form of skin cancer. An estimated 3.6 million cases of BCC are diagnosed in the U.S. each year.
- #4 Epidemiology of skin cancer – PubMedhttps://pubmed.ncbi.nlm.nih.gov/25207363/
Melanoma and nonmelanoma skin cancer (NMSC) are now the most common types of cancer in white populations. […] Both tumor entities show an increasing incidence rate worldwide but a stable or decreasing mortality rate. […] NMSC is the most common cancer in white-skinned individuals with a worldwide increasing incidence. […] The rising incidence rates of NMSC are probably caused by a combination of increased exposure to ultraviolet (UV) or sun light, increased outdoor activities, changes in clothing style, increased longevity, ozone depletion, genetics and in some cases, immune suppression. […] Cutaneous melanoma is the most rapidly increasing cancer in white populations, in the last 3 decades incidence rates have risen up to 5-fold. […] Changes in outdoor activities and exposure to sunlight during the past 50 years are an important factor for the increasing incidence of melanoma.
- #4 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
Skin cancer is the most common cancer in the United States. (1,2) […] Current estimates are that one in five Americans will develop skin cancer in their lifetime. (3) […] It is estimated that approximately 9,500 people in the U.S. are diagnosed with skin cancer every day. (4-6) […] It is estimated that the overall incidence of BCC increased by 145% between 1976-1984 and 2000-2010, and the overall incidence of SCC increased 263% over that same period. (7) […] More than 1 million Americans are living with melanoma. (8) […] It is estimated that 212,200 new cases of melanoma, 107,240 noninvasive (in situ) and 104,960 invasive, will be diagnosed in the U.S. in 2025. (6) […] Melanoma rates in the United States have been rising rapidly over the past 30 years doubling from 1982 to 2011 but trends within the past decade vary by age. (1,6,10) There has been a 31.5% increase between 2011 and 2019. (11)
- #4 Melanoma Skin Cancer Statistics | American Cancer Societyhttps://www.cancer.org/cancer/types/melanoma-skin-cancer/about/key-statistics.html
Cancer of the skin is by far the most common of all cancers in the United States. Melanoma accounts for only about 1% of skin cancers but causes a large majority of skin cancer deaths. […] The American Cancer Societys estimates for melanoma in the United States for 2025 are: About 104,960 new melanomas will be diagnosed (about 60,550 in men and 44,410 in women). About 8,430 people are expected to die of melanoma (about 5,470 men and 2,960 women). […] Melanoma death rates declined rapidly from 2013 to 2022, largely because of advances in treatment. […] The risk of melanoma increases as people age. The average age of people when it is diagnosed is 66. But melanoma is not uncommon even among those younger than 30. In fact, its one of the most common cancers in young adults (especially young women).
- #4 Melanoma of the Skin â Cancer Stat Factshttps://seer.cancer.gov/statfacts/html/melan.html
Estimated New Cases in 2025 104,960. […] Estimated Deaths in 2025 8,430. […] Melanoma of the skin represents 5.1% of all new cancer cases in the U.S. […] In 2025, it is estimated that there will be 104,960 new cases of melanoma of the skin and an estimated 8,430 people will die of this disease. […] The rate of new cases of melanoma of the skin was 21.9 per 100,000 men and women per year based on 2018â2022 cases, age-adjusted. […] For melanoma of the skin, death rates are higher among the middle-aged and elderly. The death rate was 2.0 per 100,000 men and women per year based on 2019â2023 deaths, age-adjusted. […] Keeping track of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where additional research is needed to address challenges, such as improving screening or finding better treatments. […] Using statistical models for analysis, age-adjusted rates for new melanoma of the skin cases have been rising on average 1.2% each year over 2013â2022. Age-adjusted death rates have been falling on average 2.8% each year over 2014â2023.
- #4 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
The incidence of melanoma among non-Hispanic White individuals is almost 30 times higher than that among non-Hispanic Black or Asian/Pacific Islander individuals. (12,13) […] Skin cancer in patients with darker skin tones is often diagnosed in its later stages, when its more difficult to treat. (16-20) […] Research has shown that patients with darker skin tones are less likely than patients with lighter skin tones to survive melanoma. (18-21) […] The vast majority of skin cancer deaths are from melanoma. (6) […] Nearly 20 Americans die from melanoma every day. In 2025, it is estimated that 8,430 deaths will be attributed to melanoma 5,470 men and 2,960 women. (6) […] Research indicates that men with melanoma generally have lower survival rates than women with melanoma. (6,8,24) […] Overall melanoma death rates drastically declined from 2014 through 2022 by nearly 4%. (6)
- #4 Melanoma of the Skin Statistics | Skin Cancer | CDChttps://www.cdc.gov/skin-cancer/statistics/index.html
Skin cancer is the most common form of cancer in the United States. […] Central cancer registries collect data on melanoma of the skin and nonepithelial skin cancers such as Merkel cell carcinoma. […] Data on basal cell and squamous cell carcinomas, the most common types of skin cancer, are not normally collected by central cancer registries. […] An examination of Medical Expenditure Panel Survey data suggests that each year, about 6.1 million adults are treated for basal cell and squamous cell carcinomas at a cost of about $8.9 billion. […] The Melanoma Dashboard provides state and local data to help communities address their unique melanoma prevention needs. […] National survey data about sun protection, indoor tanning, and sunburn are collected through the Youth Risk Behavior Surveillance System (for high school students) and the National Health Interview Survey (for adults aged 18 or older).
- #4 Epidemiology of Keratinocyte Skin Cancer with a Focus on Cutaneous Squamous Cell Carcinomahttps://www.mdpi.com/2072-6694/16/3/606
Nonmelanoma skin cancer is usually not recorded by cancer registries worldwide. […] A recent study demonstrated that due to changes in registration procedures such as the introduction of an automatic linkage system and especially the inclusion of multiple SCCs, the incidence rates of cutaneous SCC have increased significantly in the Netherlands since 2017. […] Although not recorded or presented in many cancer registries, most patients develop multiple cutaneous SCCs in further course. […] The number of skin cancer patients is likely to increase in the future due to demographic developments and climate-related changes in UV exposure. […] Primary prevention is still inadequate and needs to be improved to prevent further increases in the incidence of cutaneous SCC. […] The incidence of cutaneous SCC is expected to increase by 10 to 75% over the next 20 years. […] Keratinocyte skin cancer is the most common type of cancer in white populations, with SCC accounting for about 20% of keratinocyte skin cancers. […] In western Europe, Australia, and the United States, a further increase in incidence is expected in the coming years.
- #4 Epidemiology of Skin Cancer in 2024 | IntechOpenhttps://www.intechopen.com/chapters/1195964
Incidence and mortality rates varied significantly by country and region, with the highest incidence found in light-skinned populations in North America, western and northern Europe (including Denmark, Norway, and the Netherlands), and Australia/New Zealand. […] With increasing incidence rates in all age categories and geographical areas, skin cancer is still a major worldwide health issue in 2024. […] The epidemiological trends for melanoma and non-melanoma skin cancers have been described in this chapter, with special emphasis on the intricate interactions between socioeconomic, environmental, and genetic factors that affect risk. […] Reducing the worldwide incidence of skin cancer and enhancing patient outcomes require sustained investment in preventive measures, enhanced diagnostic technologies, and fair access to therapy.
- #5 Epidemiology of skin cancer – PubMedhttps://pubmed.ncbi.nlm.nih.gov/25207363/
Melanoma and nonmelanoma skin cancer (NMSC) are now the most common types of cancer in white populations. […] Both tumor entities show an increasing incidence rate worldwide but a stable or decreasing mortality rate. […] NMSC is the most common cancer in white-skinned individuals with a worldwide increasing incidence. […] The rising incidence rates of NMSC are probably caused by a combination of increased exposure to ultraviolet (UV) or sun light, increased outdoor activities, changes in clothing style, increased longevity, ozone depletion, genetics and in some cases, immune suppression. […] Cutaneous melanoma is the most rapidly increasing cancer in white populations, in the last 3 decades incidence rates have risen up to 5-fold. […] Changes in outdoor activities and exposure to sunlight during the past 50 years are an important factor for the increasing incidence of melanoma.
- #5 Melanoma Skin Cancer Statistics | American Cancer Societyhttps://www.cancer.org/cancer/types/melanoma-skin-cancer/about/key-statistics.html
Cancer of the skin is by far the most common of all cancers in the United States. Melanoma accounts for only about 1% of skin cancers but causes a large majority of skin cancer deaths. […] The American Cancer Societys estimates for melanoma in the United States for 2025 are: About 104,960 new melanomas will be diagnosed (about 60,550 in men and 44,410 in women). About 8,430 people are expected to die of melanoma (about 5,470 men and 2,960 women). […] Melanoma death rates declined rapidly from 2013 to 2022, largely because of advances in treatment. […] The risk of melanoma increases as people age. The average age of people when it is diagnosed is 66. But melanoma is not uncommon even among those younger than 30. In fact, its one of the most common cancers in young adults (especially young women).
- #5 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
The incidence of melanoma among non-Hispanic White individuals is almost 30 times higher than that among non-Hispanic Black or Asian/Pacific Islander individuals. (12,13) […] Skin cancer in patients with darker skin tones is often diagnosed in its later stages, when its more difficult to treat. (16-20) […] Research has shown that patients with darker skin tones are less likely than patients with lighter skin tones to survive melanoma. (18-21) […] The vast majority of skin cancer deaths are from melanoma. (6) […] Nearly 20 Americans die from melanoma every day. In 2025, it is estimated that 8,430 deaths will be attributed to melanoma 5,470 men and 2,960 women. (6) […] Research indicates that men with melanoma generally have lower survival rates than women with melanoma. (6,8,24) […] Overall melanoma death rates drastically declined from 2014 through 2022 by nearly 4%. (6)
- #5 Melanoma of the Skin Statistics | Skin Cancer | CDChttps://www.cdc.gov/skin-cancer/statistics/index.html
Skin cancer is the most common form of cancer in the United States. […] Central cancer registries collect data on melanoma of the skin and nonepithelial skin cancers such as Merkel cell carcinoma. […] Data on basal cell and squamous cell carcinomas, the most common types of skin cancer, are not normally collected by central cancer registries. […] An examination of Medical Expenditure Panel Survey data suggests that each year, about 6.1 million adults are treated for basal cell and squamous cell carcinomas at a cost of about $8.9 billion. […] The Melanoma Dashboard provides state and local data to help communities address their unique melanoma prevention needs. […] National survey data about sun protection, indoor tanning, and sunburn are collected through the Youth Risk Behavior Surveillance System (for high school students) and the National Health Interview Survey (for adults aged 18 or older).
- #5 Epidemiology of Keratinocyte Skin Cancer with a Focus on Cutaneous Squamous Cell Carcinomahttps://www.mdpi.com/2072-6694/16/3/606
Nonmelanoma skin cancer is usually not recorded by cancer registries worldwide. […] A recent study demonstrated that due to changes in registration procedures such as the introduction of an automatic linkage system and especially the inclusion of multiple SCCs, the incidence rates of cutaneous SCC have increased significantly in the Netherlands since 2017. […] Although not recorded or presented in many cancer registries, most patients develop multiple cutaneous SCCs in further course. […] The number of skin cancer patients is likely to increase in the future due to demographic developments and climate-related changes in UV exposure. […] Primary prevention is still inadequate and needs to be improved to prevent further increases in the incidence of cutaneous SCC. […] The incidence of cutaneous SCC is expected to increase by 10 to 75% over the next 20 years. […] Keratinocyte skin cancer is the most common type of cancer in white populations, with SCC accounting for about 20% of keratinocyte skin cancers. […] In western Europe, Australia, and the United States, a further increase in incidence is expected in the coming years.
- #6 Epidemiology of skin cancer – PubMedhttps://pubmed.ncbi.nlm.nih.gov/25207363/
Melanoma and nonmelanoma skin cancer (NMSC) are now the most common types of cancer in white populations. […] Both tumor entities show an increasing incidence rate worldwide but a stable or decreasing mortality rate. […] NMSC is the most common cancer in white-skinned individuals with a worldwide increasing incidence. […] The rising incidence rates of NMSC are probably caused by a combination of increased exposure to ultraviolet (UV) or sun light, increased outdoor activities, changes in clothing style, increased longevity, ozone depletion, genetics and in some cases, immune suppression. […] Cutaneous melanoma is the most rapidly increasing cancer in white populations, in the last 3 decades incidence rates have risen up to 5-fold. […] Changes in outdoor activities and exposure to sunlight during the past 50 years are an important factor for the increasing incidence of melanoma.
- #6 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
The incidence of melanoma among non-Hispanic White individuals is almost 30 times higher than that among non-Hispanic Black or Asian/Pacific Islander individuals. (12,13) […] Skin cancer in patients with darker skin tones is often diagnosed in its later stages, when its more difficult to treat. (16-20) […] Research has shown that patients with darker skin tones are less likely than patients with lighter skin tones to survive melanoma. (18-21) […] The vast majority of skin cancer deaths are from melanoma. (6) […] Nearly 20 Americans die from melanoma every day. In 2025, it is estimated that 8,430 deaths will be attributed to melanoma 5,470 men and 2,960 women. (6) […] Research indicates that men with melanoma generally have lower survival rates than women with melanoma. (6,8,24) […] Overall melanoma death rates drastically declined from 2014 through 2022 by nearly 4%. (6)
- #7 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
The incidence of melanoma among non-Hispanic White individuals is almost 30 times higher than that among non-Hispanic Black or Asian/Pacific Islander individuals. (12,13) […] Skin cancer in patients with darker skin tones is often diagnosed in its later stages, when its more difficult to treat. (16-20) […] Research has shown that patients with darker skin tones are less likely than patients with lighter skin tones to survive melanoma. (18-21) […] The vast majority of skin cancer deaths are from melanoma. (6) […] Nearly 20 Americans die from melanoma every day. In 2025, it is estimated that 8,430 deaths will be attributed to melanoma 5,470 men and 2,960 women. (6) […] Research indicates that men with melanoma generally have lower survival rates than women with melanoma. (6,8,24) […] Overall melanoma death rates drastically declined from 2014 through 2022 by nearly 4%. (6)
- #8 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
The incidence of melanoma among non-Hispanic White individuals is almost 30 times higher than that among non-Hispanic Black or Asian/Pacific Islander individuals. (12,13) […] Skin cancer in patients with darker skin tones is often diagnosed in its later stages, when its more difficult to treat. (16-20) […] Research has shown that patients with darker skin tones are less likely than patients with lighter skin tones to survive melanoma. (18-21) […] The vast majority of skin cancer deaths are from melanoma. (6) […] Nearly 20 Americans die from melanoma every day. In 2025, it is estimated that 8,430 deaths will be attributed to melanoma 5,470 men and 2,960 women. (6) […] Research indicates that men with melanoma generally have lower survival rates than women with melanoma. (6,8,24) […] Overall melanoma death rates drastically declined from 2014 through 2022 by nearly 4%. (6)
- #9 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
The incidence of melanoma among non-Hispanic White individuals is almost 30 times higher than that among non-Hispanic Black or Asian/Pacific Islander individuals. (12,13) […] Skin cancer in patients with darker skin tones is often diagnosed in its later stages, when its more difficult to treat. (16-20) […] Research has shown that patients with darker skin tones are less likely than patients with lighter skin tones to survive melanoma. (18-21) […] The vast majority of skin cancer deaths are from melanoma. (6) […] Nearly 20 Americans die from melanoma every day. In 2025, it is estimated that 8,430 deaths will be attributed to melanoma 5,470 men and 2,960 women. (6) […] Research indicates that men with melanoma generally have lower survival rates than women with melanoma. (6,8,24) […] Overall melanoma death rates drastically declined from 2014 through 2022 by nearly 4%. (6)
- #10 Skin cancerhttps://www.aad.org/media/stats-skin-cancer
The incidence of melanoma among non-Hispanic White individuals is almost 30 times higher than that among non-Hispanic Black or Asian/Pacific Islander individuals. (12,13) […] Skin cancer in patients with darker skin tones is often diagnosed in its later stages, when its more difficult to treat. (16-20) […] Research has shown that patients with darker skin tones are less likely than patients with lighter skin tones to survive melanoma. (18-21) […] The vast majority of skin cancer deaths are from melanoma. (6) […] Nearly 20 Americans die from melanoma every day. In 2025, it is estimated that 8,430 deaths will be attributed to melanoma 5,470 men and 2,960 women. (6) […] Research indicates that men with melanoma generally have lower survival rates than women with melanoma. (6,8,24) […] Overall melanoma death rates drastically declined from 2014 through 2022 by nearly 4%. (6)