Atrezja trójdzielna
Objawy

Atrezja trójdzielna to wrodzona wada serca charakteryzująca się brakiem lub nieprawidłowym rozwojem zastawki trójdzielnej, co uniemożliwia przepływ krwi z prawego przedsionka do prawej komory. Skutkuje to niedostatecznym utlenowaniem krwi i objawami takimi jak sinica, tachypnea, tachykardia, trudności w karmieniu oraz słaby przyrost masy ciała. Obraz kliniczny zależy od obecności dodatkowych wad, np. ubytku przegrody międzykomorowej (VSD) oraz od stopnia przepływu płucnego. W przypadku zmniejszonego przepływu płucnego sinica nasila się w pierwszych miesiącach życia, natomiast przy zwiększonym przepływie dominują objawy niewydolności serca, takie jak duszność i obrzęki. W sytuacji przełożenia wielkich naczyń obserwuje się krytyczne objawy niedokrwienia obwodowego i niskiego ciśnienia tętniczego, wymagające natychmiastowej interwencji.

Objawy atrezji trójdzielnej

Atrezja trójdzielna jest wrodzoną wadą serca, w której zastawka trójdzielna nie rozwija się prawidłowo lub całkowicie nie występuje. Wada ta blokuje przepływ krwi z prawego przedsionka do prawej komory serca, co prowadzi do niewystarczającego dopływu krwi do płuc i niedotlenienia organizmu. 12 Objawy atrezji trójdzielnej są zwykle widoczne zaraz po urodzeniu lub w ciągu pierwszych dni życia dziecka.34

Pierwsze objawy u noworodków

Większość niemowląt z atrezją trójdzielną wykazuje objawy w ciągu pierwszego tygodnia życia. Nasilenie objawów może zależeć od obecności i wielkości dodatkowych wad serca, takich jak ubytek przegrody międzykomorowej (VSD) oraz związku między głównymi naczyniami.56 Do najczęstszych objawów należą:

Zróżnicowanie objawów w zależności od przepływu płucnego

Objawy atrezji trójdzielnej mogą się różnić w zależności od tego, czy istnieje zmniejszony czy zwiększony przepływ krwi przez płuca:2122

  • Zmniejszony przepływ płucny – niemowlęta mają zazwyczaj łagodną do umiarkowanej sinicę przy urodzeniu, która z czasem nasila się, czasem dramatycznie, w ciągu pierwszych kilku miesięcy życia.23
  • Zwiększony przepływ płucny – niemowlęta zwykle wykazują objawy niewydolności serca (np. przyspieszone oddychanie, duszność podczas karmienia, słaby przyrost masy ciała, pocenie się) do 4-6 tygodnia życia.24

W przypadku przełożenia wielkich naczyń, objawy są związane z niskim przepływem krwi przez aortę do ciała. Powoduje to niskie ciśnienie krwi, przyspieszony oddech, słabe karmienie, zimne, lepkie dłonie i stopy oraz bladą, szarą barwę skóry. Niemowlęta z tymi objawami są w stanie krytycznym i wymagają natychmiastowej pomocy medycznej.25

Objawy niewydolności serca

Niektóre niemowlęta z atrezją trójdzielną mogą również rozwijać objawy niewydolności serca. Jest to szczególnie powszechne u pacjentów ze zwiększonym przepływem krwi przez płuca, na przykład gdy występuje duży ubytek przegrody międzykomorowej (VSD) bez zwężenia zastawki płucnej.2627 Objawy niewydolności serca mogą obejmować:

Progresja objawów w czasie

Bez interwencji medycznej, atrezja trójdzielna niesie ze sobą wysokie ryzyko śmiertelności w pierwszym roku życia.3536 Jednak dzięki współczesnym metodom chirurgicznym, większość dzieci z atrezją trójdzielną ma szansę na przeżycie do wieku dorosłego.37

Objawy po zabiegach chirurgicznych

Leczenie atrezji trójdzielnej zwykle wymaga serii zabiegów chirurgicznych. Po pierwszych dwóch etapach operacji (procedura Norwooda i operacja Glenna), dzieci nadal mogą wykazywać sinicę, ponieważ pełna korekcja krążenia nie jest jeszcze osiągnięta.3839 W tym okresie:

  • Dziecko może wolniej rosnąć i rozwijać się z powodu zmniejszonego poziomu tlenu we krwi40
  • Okres między procedurą Norwooda a operacją Glenna jest szczególnie wrażliwym czasem dla niemowląt41
  • Konieczne może być monitorowanie domowe w celu poprawy wyników leczenia42

Po ostatecznej operacji (procedura Fontana), gdy poziom tlenu we krwi się poprawia, można zaobserwować znaczną poprawę wzrostu i rozwoju dziecka.4344 Skóra przestaje być sina, apetyt zwiększa się, a dziecko odzyskuje energię.

Progresja choroby u starszych dzieci i dorosłych

Nawet po udanym leczeniu chirurgicznym, pacjenci z atrezją trójdzielną wymagają dożywotniego monitorowania przez kardiologa.4546 Mimo że wyniki leczenia znacznie się poprawiły, mogą wystąpić długoterminowe powikłania, które obejmują:

U niektórych pacjentów, mimo dobrego początkowego wyniku po operacjach, może zaistnieć potrzeba przeszczepu serca lub płuc w późniejszym życiu.5859

Objawy związane z długotrwałym niedotlenieniem

Długotrwałe niedotlenienie (hipoksemia) jest poważnym powikłaniem atrezji trójdzielnej i może prowadzić do specyficznych objawów i zmian w organizmie pacjenta.6061

Zmiany fizyczne związane z przewlekłym niedotlenieniem

U dzieci i dorosłych z długotrwałym niedotlenieniem mogą wystąpić następujące objawy:6263

  • Palce pałeczkowate (clubbing) – nieprawidłowy kształt opuszków palców i paznokci, będący oznaką przewlekłego niedoboru tlenu6465
  • Objawu wtórnej czerwienicy (poliglobulii) – zwiększonej liczby czerwonych krwinek jako mechanizmu kompensacyjnego organizmu66

Objawy neurologiczne związane z niedotlenieniem

Długotrwałe niedotlenienie i zespół nadlepkości krwi mogą prowadzić do następujących objawów neurologicznych:67

Znaczenie wczesnej diagnostyki i leczenia

Szybkie rozpoznanie i wczesne leczenie atrezji trójdzielnej ma kluczowe znaczenie dla poprawy rokowania niemowląt z tą wadą serca.6869 Diagnoza może być postawiona już w trakcie rutynowego badania ultrasonograficznego w czasie ciąży lub zaraz po urodzeniu, gdy lekarz obserwuje objawy kliniczne i słyszy szmer serca podczas osłuchiwania.7071

Badanie pulksoksymetryczne (pomiar poziomu tlenu we krwi) jest prostym, bezbolesnym testem, który może pomóc w identyfikacji noworodków z krytycznymi wrodzonymi wadami serca, takimi jak atrezja trójdzielna, zanim pokażą jakiekolwiek objawy.72

Choć operacje nie naprawiają całkowicie serca, znacznie poprawiają stan dziecka i jakość życia. Wyniki trzyetapowego leczenia chirurgicznego atrezji trójdzielnej są generalnie dobre, ze wskaźnikami przeżycia wynoszącymi od 75% do 95%, w zależności od czynników indywidualnych każdego dziecka i otrzymanej opieki.7374

Po leczeniu, dzieci z atrezją trójdzielną potrzebują regularnych kontroli lekarskich, najlepiej u kardiologa pediatrycznego wyspecjalizowanego w wadach wrodzonych serca. Również dorośli leczeni z powodu atrezji trójdzielnej wymagają dożywotnich kontroli, najlepiej u lekarza wyspecjalizowanego w wadach wrodzonych serca u dorosłych.75

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  1. 10.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Tricuspid Atresia – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK554495/
    Tricuspid atresia is a congenital heart defect that results in cyanosis due to the absence of communication between the right atrium and ventricle caused by the complete agenesis of the tricuspid valve. This condition has several subtypes with varied clinical presentations determined by the extent of pulmonary blood flow. […] Without intervention within the first year of life, tricuspid atresia carries a high mortality rate. […] Patients often present with cyanosis in the newborn period, especially after the closure of the ductus. […] Patients with a VSD and without PS often experience substantial pulmonary blood flow. Such cases could be missed at birth, as these individuals do not present with cyanosis. The condition may become apparent when pulmonary vascular resistance drops, leading to pulmonary overcirculation. This condition manifests with signs and symptoms of heart failure, such as tachypnea or respiratory distress, poor feeding, and impaired growth.
  • #2 Tricuspid Valve Atresia | Norton Children’s Louisville, Ky.
    https://nortonchildrens.com/services/cardiology/conditions/congenital-heart-disease/tricuspid-atresia/
    Tricuspid valve atresia is a congenital heart defect in which the heart’s tricuspid valve doesn’t develop. This means that blood can’t flow from the heart’s right atrium (upper receiving chamber) to the right ventricle (lower pumping chamber) as it should. Because of this, the right ventricle does not properly develop prior to birth. Therefore, the child will have a single functioning left ventricle as their only way to pump blood to their body and lungs. […] A baby born with tricuspid atresia often has serious symptoms soon after birth because blood flow to the lungs is much lower than normal. […] A newborn with tricuspid atresia usually will: Have bluish skin (cyanosis), Breathe fast, Have problems feeding, Get tired quickly when feeding, Be less active than most babies. […] Treatment for tricuspid valve atresia can improve the baby’s condition, but it can’t make the heart work like one without a defect. A child born with tricuspid valve atresia will regularly see a pediatric cardiologist throughout childhood and as an adult.
  • #3 Tricuspid atresia – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/tricuspid-atresia/symptoms-causes/syc-20368392
    Tricuspid atresia symptoms are usually seen soon after birth. Symptoms of tricuspid atresia may include: […] People with tricuspid atresia can’t get enough oxygen through the body. So they tire easily and they are often short of breath. Their skin and lips may look blue or gray. […] Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: […] Tricuspid atresia restricts blood flow from the heart to the lungs. The right lower heart chamber is small and underdeveloped. A life-threatening complication of tricuspid atresia is a lack of oxygen to the body’s tissues. This condition is called hypoxemia. […] Prompt treatment greatly improves the outcome for babies with tricuspid atresia. But complications may develop later in life. Complications of tricuspid atresia may include: Easy tiring during activity, Irregular heart rhythms, Kidney or liver disease, Heart failure.
  • #4 Tricuspid Atresia: Symptoms, Treatment & Prognosis
    https://my.clevelandclinic.org/health/diseases/14789-tricuspid-atresia
    In most cases, babies with tricuspid atresia have symptoms within a week of birth. […] Tricuspid atresia symptoms may include: Fatigue, Heart murmur (unusual heart sounds), Shortness of breath (dyspnea) and rapid breathing (tachypnea), Skin and lips that are bluish (cyanosis), Slow growth, Trouble with feeding. […] In addition, some babies with this condition can develop heart failure symptoms like sweating while feeding (in a newborn) or not gaining proper weight. […] Children with this condition can have complications between stages of repair. A healthcare provider may recommend home monitoring to improve outcomes for your child. […] Most babies with this condition won’t reach their first birthday without an operation. […] But most children who have the surgeries survive and live to be adults. One study found that most people with tricuspid atresia are alive 20 years later. […] Although surgery isn’t a cure, the short-term and intermediate-term outlook for children who have surgery is promising. The outlook is usually worse for children who have surgery later in life.
  • #5 Tricuspid Atresia | Symptoms, Diagnosis & Treatment
    https://www.cincinnatichildrens.org/health/t/tricuspid-atresia
    Tricuspid atresia is a type of congenital (a condition you are born with) heart disease. In this disease, the valve between the right atrium and right ventricle doesnt develop. […] The signs and symptoms of tricuspid atresia depend on the presence and size of the ventricular septal defect and the relationship of the great arteries. […] In this case, the newborn baby with tricuspid atresia will have a low oxygen level and a dusky, blue color, called cyanosis. This cyanosis may be noted at birth or it may be noticed after several days when the ductus arteriosus closes. As the ductus closes, the cyanosis worsens. If the cyanosis is severe enough, the baby will develop symptoms of poor oxygenation. This may be fast breathing or poor feeding. […] Occasionally, there is an increased amount of blood flow to the lungs. This baby may have little to no cyanosis. They will likely develop congestive heart failure. Pulmonary edema (swelling in the lungs) can develop and cause the baby to breathe harder. The combination of increased heart and lung work uses large amounts of calories and results in congestive heart failure (CHF).
  • #6 About Tricuspid Atresia | Congenital Heart Defects (CHDs) | CDC
    https://www.cdc.gov/heart-defects/about/tricuspid-atresia.html
    Babies born with tricuspid atresia will show symptoms at birth or very soon afterwards. They may have a bluish skin color, called cyanosis, because their blood doesn’t carry enough oxygen. Infants with tricuspid atresia can have additional symptoms such as: […] Babies born with tricuspid atresia will show symptoms at birth or very soon afterwards. During a physical examination, a doctor can see the symptom or hear a heart murmur when listening with a stethoscope. A heart murmur is an abnormal „whooshing” sound caused by blood not flowing properly. […] Infants who have these surgeries are not cured; they might have lifelong complications. If the tricuspid atresia is very complex, or the heart becomes weak after the surgeries, a heart transplant might be needed. Children who receive a heart transplant will need to take medicines for the rest of their lives. The medicines help prevent rejection of the new heart.
  • #7 Tricuspid Atresia – Stanford Medicine Children’s Health
    https://www.stanfordchildrens.org/en/topic/default?id=tricuspid-atresia-90-P01819
    Symptoms of tricuspid atresia occur shortly after birth. Common symptoms may include: […] Blue color of the skin, lips, and nail beds (cyanosis) […] Fast breathing […] Trouble breathing […] Fast heart rate […] Poor feeding. […] Babies will have bluish skin (cyanosis) after the first 2 surgeries, or until the final Fontan procedure is done. Your child may grow and develop slowly because of decreased oxygen in the blood. After the Fontan procedure, when oxygen levels get better, you will likely see large improvements in your child’s growth and development.
  • #8 Tricuspid Atresia – Seattle Children’s Hospital
    https://www.seattlechildrens.org/conditions/tricuspid-atresia/
    Most babies with tricuspid atresia show symptoms within the first few hours after birth. In some babies, it may take a few days or weeks for symptoms to appear. […] Symptoms of tricuspid atresia may include: Heart murmur (the sound of blood moving in the heart in a way thats not normal) […] Skin may look blue or purple tinged, mottled (different shades or colors), grayish or paler than usual; the lips, mouth, gums, fingernails or toenails may look bluish (cyanosis) […] Fast breathing […] Working hard to breathe […] Poor feeding […] Poor weight gain or growth.
  • #9 Tricuspid Atresia | Boston Children’s Hospital
    https://www.childrenshospital.org/conditions/tricuspid-atresia
    The symptoms of tricuspid atresia may include: Rapid breathing, Rapid heartbeat, Blue color of the skin, lips, and nailbeds (cyanosis), Sweating, Disinterest in feeding or tiring while feeding, Poor weight gain, Heart murmur (detected by doctor). […] Surgical techniques for tricuspid atresia and its associated defects are continually being refined with long-term outcomes continually improving. Nevertheless, children with tricuspid atresia will need lifelong monitoring and medication, since they will always be at some risk for arrhythmias, infections, heart failure, or stroke.
  • #10 Tricuspid atresia | Congenital Heart Defect (CHD) | Children’s Wisconsin
    https://childrenswi.org/medical-care/herma-heart/conditions/tricuspid-atresia
    Symptoms are noted shortly after birth. The following are the most common symptoms of tricuspid atresia, however, each child may experience symptoms differently. Tricuspid atresia symptoms may include: […] Blue color of the skin, lips, and nailbeds. […] Rapid breathing […] Labored breathing […] Rapid heart rate […] Cool, clammy skin. […] Infants will remain cyanotic after the first two operations until the final operation (Fontan procedure) is performed. Your child will likely grow and develop more slowly than the average baby because of the lower amounts of oxygen available for the body’s needs. Following the Fontan procedure, when oxygen levels improve, many children will see major improvements in growth and development, and can eventually catch up to normal children.
  • #11 Tricuspid Atresia
    https://healthlibrary.ecuhealth.org/Conditions/Pregnancy/90,P01819
    Symptoms of TA occur shortly after birth. Common symptoms may include: […] Blue color of the skin, lips, and nail beds (cyanosis) […] Fast breathing […] Trouble breathing […] Fast heart rate […] Poor feeding […] The symptoms of TA may look like other health conditions. Have your child see their healthcare provider for a diagnosis. […] Babies will have a blue color to their skin (cyanosis) after the first two surgeries, or until the final Fontan procedure is done. Your child may grow and develop slowly because of decreased oxygen in the blood. After the Fontan procedure, when oxygen levels get better, you will likely see large improvements in your child’s growth and development.
  • #12 Content – Health Encyclopedia – University of Rochester Medical Center
    https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid=P01819
    Symptoms of TA occur shortly after birth. Common symptoms may include: […] Blue color of the skin, lips, and nail beds (cyanosis) […] Fast breathing […] Trouble breathing […] Fast heart rate […] Poor feeding. […] Babies will have a blue color to their skin (cyanosis) after the first two surgeries, or until the final Fontan procedure is done. Your child may grow and develop slowly because of decreased oxygen in the blood. After the Fontan procedure, when oxygen levels get better, you will likely see large improvements in your child’s growth and development.
  • #13 Tricuspid Atresia | Children’s Hospital of Philadelphia
    https://www.chop.edu/conditions-diseases/tricuspid-atresia
    Tricuspid atresia symptoms in children include: […] Blue or purple tint to lips, skin and nails (cyanosis) […] Heart murmur, or abnormal heart sound when a doctor listens with a stethoscope […] Shortness of breath […] Difficulty feeding […] Poor weight gain […] Fatigue […] Abnormally shaped fingertips, called clubbing. […] Because of enormous strides in medicine and technology, today many children born with tricuspid atresia go on to lead healthy, productive lives as adults. […] Though early outcomes for children with single ventricle heart defects after staged reconstruction have greatly improved over the years, the time between the Norwood procedure and the Glenn operation is a very vulnerable time for infants. […] Children with tricuspid atresia require life-long care by a cardiologist. Many remain on medications for life. Additional surgeries may be required. […] As patients with Fontan circulation get older, doctors are recognizing that, while some do fine, many experience complications. These complications can include lung, liver and gastrointestinal diseases.
  • #14 Tricuspid Atresia (for Parents) | Nemours KidsHealth
    https://kidshealth.org/en/parents/tricuspid-atresia.html
    Tricuspid atresia is a congenital heart defect (this means that a baby who has it is born with it). It happens when the heart’s tricuspid valve does not develop. As a result, blood can’t flow from the heart’s right atrium (upper receiving chamber) to the right ventricle (lower pumping chamber) as it should. […] A baby born with tricuspid atresia (try-KUS-ped ah-TREE-zhah) often has serious symptoms soon after birth because blood flow to the lungs is much less than normal. […] Soon after birth, a newborn with tricuspid atresia usually will: have bluish skin (cyanosis), breathe fast or hard, have problems feeding, get tired quickly when feeding, be less active than most babies.
  • #15 Tricuspid atresia: MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/001110.htm
    Symptoms include: […] Bluish color to the skin (cyanosis) due to low oxygen level in the blood […] Fast breathing […] Fatigue […] Poor growth […] Shortness of breath […] A heart murmur is often present at birth and may increase in loudness over several months. […] During stage I and II, the child may still look blue (cyanotic). […] After this final step, the baby’s skin is no longer blue.
  • #16 Tricuspid Atresia – UF Health
    https://ufhealth.org/conditions-and-treatments/tricuspid-atresia
    Symptoms include: […] Bluish color to the skin (cyanosis) due to low oxygen level in the blood […] Fast breathing […] Fatigue […] Poor growth […] Shortness of breath.
  • #17 Tricuspid Atresia | Arkansas Children’s
    https://www.archildrens.org/programs-and-services/cardiology/conditions/tricuspid-atresia
    Babies with tricuspid atresia usually have symptoms shortly after birth. These symptoms may vary depending on the other heart defects the baby has. Symptoms may include: Fast heart rate, Trouble breathing, Skin or lips that look blue, Poor feeding or weight gain, Tiring easily, Heart murmur. […] Many babies with tricuspid atresia need surgery shortly after birth.
  • #18 Tricuspid Atresia | Heart Defects | NCBDDD | CDC
    http://med.iiab.me/modules/en-cdc/www.cdc.gov/ncbddd/heartdefects/tricuspid-atresia.html
    Babies born with tricuspid atresia will show symptoms at birth or very soon afterwards. They may have a bluish looking skin color, called cyanosis, because their blood doesnt carry enough oxygen. Infants with tricuspid atresia can have additional symptoms such as: […] Problems breathing […] Ashen or bluish skin color […] Poor feeding […] Extreme sleepiness. […] During a physical examination, a doctor can see the symptoms, such as bluish skin or problems breathing. Using a stethoscope, a doctor will check for a heart murmur (an abnormal whooshing sound caused by blood not flowing properly), or other sounds that may indicate a heart problem. However, it is not uncommon for a heart murmur to be absent right at birth. […] If a doctor suspects that there might be a problem, the doctor can request one or more tests to confirm the diagnosis of tricuspid atresia. The most common test is an echocardiogram. This is an ultrasound of the heart that can show problems with the structure of the heart, like holes in the walls between the chambers, and any irregular blood flow.
  • #19 Tricuspid Atresia (for Parents) – Humana – Louisiana
    https://kidshealth.org/HumanaLouisiana/en/parents/tricuspid-atresia.html
    A baby born with tricuspid atresia often has serious symptoms soon after birth because blood flow to the lungs is much less than normal. […] Soon after birth, a newborn with tricuspid atresia usually will: have bluish skin (cyanosis), breathe fast or hard, have problems feeding, get tired quickly when feeding, be less active than most babies.
  • #20 Tricuspid Atresia | Rady Children’s Hospital
    https://www.rchsd.org/health-article/tricuspid-atresia/
    A baby born with tricuspid atresia often has serious symptoms soon after birth because blood flow to the lungs is much less than normal. […] Soon after birth, a newborn with tricuspid atresia usually will: have bluish skin (cyanosis), breathe fast, have problems feeding, get tired quickly when feeding, be less active than most babies. […] Treatments for tricuspid atresia improve the babys condition, but cant make the heart work like one without a defect. A child born with tricuspid atresia will regularly see a cardiologist (a doctor who treats heart problems) throughout childhood and as an adult.
  • #21 Tricuspid Atresia – Pediatrics – Merck Manual Professional Edition
    https://www.merckmanuals.com/professional/pediatrics/congenital-cardiovascular-anomalies/tricuspid-atresia
    Infants with decreased pulmonary blood flow usually have mild-to-moderate cyanosis at birth, which increases, sometimes dramatically, over the first several months of life. […] Infants with increased pulmonary blood flow usually show signs of heart failure (eg, tachypnea, dyspnea with feeding, poor weight gain, diaphoresis) by age 4 to 6 weeks. […] Infants with decreased pulmonary blood flow have progressively worsening cyanosis; infants with increased pulmonary blood flow usually have heart failure (eg, tachypnea, dyspnea with feeding, poor weight gain, diaphoresis).
  • #22 Tricuspid Atresia – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK554495/
    Tricuspid atresia is a congenital heart defect that results in cyanosis due to the absence of communication between the right atrium and ventricle caused by the complete agenesis of the tricuspid valve. This condition has several subtypes with varied clinical presentations determined by the extent of pulmonary blood flow. […] Without intervention within the first year of life, tricuspid atresia carries a high mortality rate. […] Patients often present with cyanosis in the newborn period, especially after the closure of the ductus. […] Patients with a VSD and without PS often experience substantial pulmonary blood flow. Such cases could be missed at birth, as these individuals do not present with cyanosis. The condition may become apparent when pulmonary vascular resistance drops, leading to pulmonary overcirculation. This condition manifests with signs and symptoms of heart failure, such as tachypnea or respiratory distress, poor feeding, and impaired growth.
  • #23 Tricuspid Atresia Treatment & Management: Medical Care, Surgical Care, Diet and Activity
    https://emedicine.medscape.com/article/158359-treatment
    The cohort of infants with decreased pulmonary blood flow encompasses most of the infants with tricuspid atresia. Marked cyanosis and hypoxemia characterize the clinical course. Acidemia may occur if the hypoxemia is profound, and death can ensue. […] Infants with increased pulmonary blood flow have an associated unrestrictive ventricular septal defect and transposed great vessels. They present with severe congestive heart failure and benefit from digitalis and diuretic therapy until an operative intervention can be undertaken to restrict the pulmonary blood flow. […] The intelligent application of palliative procedures to control the amount of pulmonary blood flow in this lesion improves the survival of infants with tricuspid atresia. With standard palliative procedures, 50% of these infants can survive into their teen years. Nonetheless, these children are at risk for developing complications of the disease, including paradoxical emboli, stroke, brain abscess, polycythemia, progressive cardiac dilatation, ventricular dysfunction, mitral valve insufficiency, and arrhythmias.
  • #24 Tricuspid Atresia | Symptoms, Diagnosis & Treatment
    https://www.cincinnatichildrens.org/health/t/tricuspid-atresia
    The symptoms of congestive heart failure are fast breathing, fast heart rate, sweating with feeds and poor weight gain. If there is transposition of the great arteries, the symptoms are related to low blood flow through the aorta and out to the body. This results in low blood pressure, fast breathing, poor feeding, cold, clammy hands and feet, and a pale, gray color. Infants with these symptoms are critically ill. They need emergency medical attention.
  • #25 Tricuspid Atresia | Symptoms, Diagnosis & Treatment
    https://www.cincinnatichildrens.org/health/t/tricuspid-atresia
    The symptoms of congestive heart failure are fast breathing, fast heart rate, sweating with feeds and poor weight gain. If there is transposition of the great arteries, the symptoms are related to low blood flow through the aorta and out to the body. This results in low blood pressure, fast breathing, poor feeding, cold, clammy hands and feet, and a pale, gray color. Infants with these symptoms are critically ill. They need emergency medical attention.
  • #26 Tricuspid atresia | Health Library | Memorial Health System
    https://www.mhsystem.org/health-library/con-20316967/
    Many babies born with tricuspid atresia also have a hole between the lower heart chambers. This hole is called a ventricular septal defect (VSD). If this occurs, some blood can flow through the hole directly to the main lung artery. The amount of blood going to the lungs depends on the size of the VSD and whether the pulmonary valve is narrowed. If the VSD is large, too much blood can move to the lungs. This can cause heart failure.
  • #27 Tricuspid atresia | Altru Health System
    https://www.altru.org/health-library/conditions/tricuspid-atresia
    Tricuspid atresia symptoms are usually seen soon after birth. Symptoms of tricuspid atresia may include: […] Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: […] Tricuspid atresia restricts blood flow from the heart to the lungs. The right lower heart chamber is small and underdeveloped. A life-threatening complication of tricuspid atresia is a lack of oxygen to the body’s tissues. This condition is called hypoxemia. […] Prompt treatment greatly improves the outcome for babies with tricuspid atresia. But complications may develop later in life. Complications of tricuspid atresia may include: […] Many babies born with tricuspid atresia also have a hole between the lower heart chambers. This hole is called a ventricular septal defect (VSD). If this occurs, some blood can flow through the hole directly to the main lung artery. The amount of blood going to the lungs depends on the size of the VSD and whether the pulmonary valve is narrowed. If the VSD is large, too much blood can move to the lungs. This can cause heart failure.
  • #28 Mayo Clinic Health Library – Tricuspid atresia | Swiss Medical Network
    https://www.swissmedical.net/en/healtcare-library/con-20316967
    People with tricuspid atresia can’t get enough oxygen through the body. So they tire easily and they are often short of breath. Their skin and lips may look blue or gray. […] Tricuspid atresia symptoms are usually seen soon after birth. Symptoms of tricuspid atresia may include: Blue or gray skin and lips due to low blood oxygen levels, Difficulty breathing, Tiring easily, especially during feedings, Slow growth and poor weight gain. […] Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: Fatigue and weakness, Shortness of breath, Swelling in the legs, ankles and feet, Swelling of the belly area, a condition called ascites, Sudden weight gain from a buildup of fluid. […] Tricuspid atresia restricts blood flow from the heart to the lungs. The right lower heart chamber is small and underdeveloped. A life-threatening complication of tricuspid atresia is a lack of oxygen to the body’s tissues. This condition is called hypoxemia.
  • #29 Tricuspid atresia // Middlesex Health
    https://middlesexhealth.org/learning-center/diseases-and-conditions/tricuspid-atresia
    Tricuspid atresia symptoms are usually seen soon after birth. Symptoms of tricuspid atresia may include: […] Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: […] Tricuspid atresia restricts blood flow from the heart to the lungs. The right lower heart chamber is small and underdeveloped. A life-threatening complication of tricuspid atresia is a lack of oxygen to the body’s tissues. This condition is called hypoxemia. […] Prompt treatment greatly improves the outcome for babies with tricuspid atresia. But complications may develop later in life. Complications of tricuspid atresia may include: Easy tiring during activity, Irregular heart rhythms, Kidney or liver disease, Heart failure.
  • #30 Tricuspid atresia // Middlesex Health
    https://middlesexhealth.org/learning-center/diseases-and-conditions/tricuspid-atresia
    Tricuspid atresia symptoms are usually seen soon after birth. Symptoms of tricuspid atresia may include: […] Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: […] Tricuspid atresia restricts blood flow from the heart to the lungs. The right lower heart chamber is small and underdeveloped. A life-threatening complication of tricuspid atresia is a lack of oxygen to the body’s tissues. This condition is called hypoxemia. […] Prompt treatment greatly improves the outcome for babies with tricuspid atresia. But complications may develop later in life. Complications of tricuspid atresia may include: Easy tiring during activity, Irregular heart rhythms, Kidney or liver disease, Heart failure.
  • #31 Mayo Clinic Health Library – Tricuspid atresia | Swiss Medical Network
    https://www.swissmedical.net/en/healtcare-library/con-20316967
    People with tricuspid atresia can’t get enough oxygen through the body. So they tire easily and they are often short of breath. Their skin and lips may look blue or gray. […] Tricuspid atresia symptoms are usually seen soon after birth. Symptoms of tricuspid atresia may include: Blue or gray skin and lips due to low blood oxygen levels, Difficulty breathing, Tiring easily, especially during feedings, Slow growth and poor weight gain. […] Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: Fatigue and weakness, Shortness of breath, Swelling in the legs, ankles and feet, Swelling of the belly area, a condition called ascites, Sudden weight gain from a buildup of fluid. […] Tricuspid atresia restricts blood flow from the heart to the lungs. The right lower heart chamber is small and underdeveloped. A life-threatening complication of tricuspid atresia is a lack of oxygen to the body’s tissues. This condition is called hypoxemia.
  • #32 SSA – POMS: DI 23022.595 – Tricuspid Atresia – 09/09/2020
    https://secure.ssa.gov/poms.nsf/lnx/0423022595
    Tricuspid atresia is a rare type of congenital heart disease in which the tricuspid valve is missing, abnormally developed or blocked by a solid sheet of tissue. The defect blocks blood flow from the right atrium of the heart to the right ventricle of the heart. As a result, the right ventricle tends to be very small and underdeveloped (hypoplastic). […] Adults, who had corrective heart surgeries as infants, may develop problems with their heart functioning later in life. Over time, the surgical treatments that were used at infancy to repair the heart defect may leave scar tissue behind, increasing the chances of abnormal heart rhythm (arrhythmia), and of developing a focus for subacute endocarditis. […] Physical findings: Cyanosis (bluish discoloration of the skin); Tires easily especially during feeding; Difficulty breathing, and Slow growth; Symptoms of heart failure including fatigue, swelling in the legs, ankles, feet, and abdomen; Sudden weight gain from fluid retention; and Irregular or rapid heartbeat.
  • #33 Tricuspid Atresia: Symptoms, Treatment & Prognosis
    https://my.clevelandclinic.org/health/diseases/14789-tricuspid-atresia
    In most cases, babies with tricuspid atresia have symptoms within a week of birth. […] Tricuspid atresia symptoms may include: Fatigue, Heart murmur (unusual heart sounds), Shortness of breath (dyspnea) and rapid breathing (tachypnea), Skin and lips that are bluish (cyanosis), Slow growth, Trouble with feeding. […] In addition, some babies with this condition can develop heart failure symptoms like sweating while feeding (in a newborn) or not gaining proper weight. […] Children with this condition can have complications between stages of repair. A healthcare provider may recommend home monitoring to improve outcomes for your child. […] Most babies with this condition won’t reach their first birthday without an operation. […] But most children who have the surgeries survive and live to be adults. One study found that most people with tricuspid atresia are alive 20 years later. […] Although surgery isn’t a cure, the short-term and intermediate-term outlook for children who have surgery is promising. The outlook is usually worse for children who have surgery later in life.
  • #34
    https://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=abp6569
    Symptoms may include: […] A blue tint to the skin, lips, or fingernails. […] Fast breathing. […] Sweating while feeding. […] Not eating well. […] Being fussy a lot of the time.
  • #35 Tricuspid Atresia – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK554495/
    The majority of unoperated patients face a high risk of mortality within the first year of life. […] In the current era of early diagnosis and effective surgical interventions, individuals with tricuspid atresia commonly survive well into adulthood, maintaining good functional capacity. Operative mortality associated with the Fontan procedure is consistently below 2%. […] Surgical outcomes have significantly improved due to advancements in surgical techniques and innovations for addressing patients’ conditions. […] Tricuspid atresia can lead to various long-term complications, including Fontan-associated liver disease (characterized by liver fibrosis and cirrhosis), renal dysfunction, somatic growth problems, psychosocial and neurodevelopmental issues, and decreased exercise tolerance.
  • #36 Tricuspid Atresia: Background, Pathophysiology, Etiology
    https://emedicine.medscape.com/article/158359-overview
    Tricuspid atresia is the third most common form of cyanotic congenital heart disease, with a prevalence of 1.03 per 10,000 live births. The deformity consists of a complete lack of formation of the tricuspid valve with absence of direct connection between the right atrium and right ventricle. […] The anomaly is congenital and is evident at birth. […] Depending on the degree of obstruction and associated anomalies, tricuspid atresia may be lethal at birth. Without repair, the patient rarely survives to adulthood. […] The 1-year survival rate after the Fontan operation is 85%; the 5-year survival rate is 78%. Because the procedure eliminates cyanosis, polycythemia and left ventricular volume overload are relieved; therefore, this population can be expected to live longer.
  • #37 Tricuspid Atresia: Symptoms, Treatment & Prognosis
    https://my.clevelandclinic.org/health/diseases/14789-tricuspid-atresia
    In most cases, babies with tricuspid atresia have symptoms within a week of birth. […] Tricuspid atresia symptoms may include: Fatigue, Heart murmur (unusual heart sounds), Shortness of breath (dyspnea) and rapid breathing (tachypnea), Skin and lips that are bluish (cyanosis), Slow growth, Trouble with feeding. […] In addition, some babies with this condition can develop heart failure symptoms like sweating while feeding (in a newborn) or not gaining proper weight. […] Children with this condition can have complications between stages of repair. A healthcare provider may recommend home monitoring to improve outcomes for your child. […] Most babies with this condition won’t reach their first birthday without an operation. […] But most children who have the surgeries survive and live to be adults. One study found that most people with tricuspid atresia are alive 20 years later. […] Although surgery isn’t a cure, the short-term and intermediate-term outlook for children who have surgery is promising. The outlook is usually worse for children who have surgery later in life.
  • #38 Tricuspid Atresia
    https://healthlibrary.brighamandwomens.org/library/TestsProcedures/Cardiovascular/90,P01819
    Heart rhythm problems (arrhythmias) […] Less ability to exercise […] Heart failure […] Poor growth and development […] Death. […] Babies will have a blue color to their skin (cyanosis) after the first two surgeries, or until the final Fontan procedure is done. Your child may grow and develop slowly because of decreased oxygen in the blood. After the Fontan procedure, when oxygen levels get better, you will likely see large improvements in your child’s growth and development.
  • #39 Tricuspid atresia: MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/001110.htm
    Symptoms include: […] Bluish color to the skin (cyanosis) due to low oxygen level in the blood […] Fast breathing […] Fatigue […] Poor growth […] Shortness of breath […] A heart murmur is often present at birth and may increase in loudness over several months. […] During stage I and II, the child may still look blue (cyanotic). […] After this final step, the baby’s skin is no longer blue.
  • #40 Content – Health Encyclopedia – University of Rochester Medical Center
    https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid=P01819
    Symptoms of TA occur shortly after birth. Common symptoms may include: […] Blue color of the skin, lips, and nail beds (cyanosis) […] Fast breathing […] Trouble breathing […] Fast heart rate […] Poor feeding. […] Babies will have a blue color to their skin (cyanosis) after the first two surgeries, or until the final Fontan procedure is done. Your child may grow and develop slowly because of decreased oxygen in the blood. After the Fontan procedure, when oxygen levels get better, you will likely see large improvements in your child’s growth and development.
  • #41 Tricuspid Atresia | Children’s Hospital of Philadelphia
    https://www.chop.edu/conditions-diseases/tricuspid-atresia
    Tricuspid atresia symptoms in children include: […] Blue or purple tint to lips, skin and nails (cyanosis) […] Heart murmur, or abnormal heart sound when a doctor listens with a stethoscope […] Shortness of breath […] Difficulty feeding […] Poor weight gain […] Fatigue […] Abnormally shaped fingertips, called clubbing. […] Because of enormous strides in medicine and technology, today many children born with tricuspid atresia go on to lead healthy, productive lives as adults. […] Though early outcomes for children with single ventricle heart defects after staged reconstruction have greatly improved over the years, the time between the Norwood procedure and the Glenn operation is a very vulnerable time for infants. […] Children with tricuspid atresia require life-long care by a cardiologist. Many remain on medications for life. Additional surgeries may be required. […] As patients with Fontan circulation get older, doctors are recognizing that, while some do fine, many experience complications. These complications can include lung, liver and gastrointestinal diseases.
  • #42 Tricuspid Atresia: Symptoms, Treatment & Prognosis
    https://my.clevelandclinic.org/health/diseases/14789-tricuspid-atresia
    In most cases, babies with tricuspid atresia have symptoms within a week of birth. […] Tricuspid atresia symptoms may include: Fatigue, Heart murmur (unusual heart sounds), Shortness of breath (dyspnea) and rapid breathing (tachypnea), Skin and lips that are bluish (cyanosis), Slow growth, Trouble with feeding. […] In addition, some babies with this condition can develop heart failure symptoms like sweating while feeding (in a newborn) or not gaining proper weight. […] Children with this condition can have complications between stages of repair. A healthcare provider may recommend home monitoring to improve outcomes for your child. […] Most babies with this condition won’t reach their first birthday without an operation. […] But most children who have the surgeries survive and live to be adults. One study found that most people with tricuspid atresia are alive 20 years later. […] Although surgery isn’t a cure, the short-term and intermediate-term outlook for children who have surgery is promising. The outlook is usually worse for children who have surgery later in life.
  • #43 Content – Health Encyclopedia – University of Rochester Medical Center
    https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid=P01819
    Symptoms of TA occur shortly after birth. Common symptoms may include: […] Blue color of the skin, lips, and nail beds (cyanosis) […] Fast breathing […] Trouble breathing […] Fast heart rate […] Poor feeding. […] Babies will have a blue color to their skin (cyanosis) after the first two surgeries, or until the final Fontan procedure is done. Your child may grow and develop slowly because of decreased oxygen in the blood. After the Fontan procedure, when oxygen levels get better, you will likely see large improvements in your child’s growth and development.
  • #44 Tricuspid Atresia > Fact Sheets > Yale Medicine
    https://www.yalemedicine.org/conditions/tricuspid-atresia
    Babies born with tricuspid atresia may have a bluish discoloration of their skin and mouth, heart failure, as well as difficulty breathing and eating. […] Babies with tricuspid atresia experience one or more of the following symptoms: Bluish skin, Difficulty breathing, Fatigue or extreme sleepiness, Difficulty feeding, Poor weight gain, A heart murmur. […] If tricuspid atresia is left untreated, patients usually die within the first year of life. But patients with tricuspid atresia who undergo all three surgical procedures experience improvement in their symptoms. Their skin stops appearing bluish because oxygen-rich blood is able to circulate throughout the body, their appetite increases, and they regain energy.
  • #45 Tricuspid Atresia | Children’s Hospital of Philadelphia
    https://www.chop.edu/conditions-diseases/tricuspid-atresia
    Tricuspid atresia symptoms in children include: […] Blue or purple tint to lips, skin and nails (cyanosis) […] Heart murmur, or abnormal heart sound when a doctor listens with a stethoscope […] Shortness of breath […] Difficulty feeding […] Poor weight gain […] Fatigue […] Abnormally shaped fingertips, called clubbing. […] Because of enormous strides in medicine and technology, today many children born with tricuspid atresia go on to lead healthy, productive lives as adults. […] Though early outcomes for children with single ventricle heart defects after staged reconstruction have greatly improved over the years, the time between the Norwood procedure and the Glenn operation is a very vulnerable time for infants. […] Children with tricuspid atresia require life-long care by a cardiologist. Many remain on medications for life. Additional surgeries may be required. […] As patients with Fontan circulation get older, doctors are recognizing that, while some do fine, many experience complications. These complications can include lung, liver and gastrointestinal diseases.
  • #46 Tricuspid Atresia | Boston Children’s Hospital
    https://www.childrenshospital.org/conditions/tricuspid-atresia
    The symptoms of tricuspid atresia may include: Rapid breathing, Rapid heartbeat, Blue color of the skin, lips, and nailbeds (cyanosis), Sweating, Disinterest in feeding or tiring while feeding, Poor weight gain, Heart murmur (detected by doctor). […] Surgical techniques for tricuspid atresia and its associated defects are continually being refined with long-term outcomes continually improving. Nevertheless, children with tricuspid atresia will need lifelong monitoring and medication, since they will always be at some risk for arrhythmias, infections, heart failure, or stroke.
  • #47 Tricuspid atresia – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/tricuspid-atresia/symptoms-causes/syc-20368392
    Tricuspid atresia symptoms are usually seen soon after birth. Symptoms of tricuspid atresia may include: […] People with tricuspid atresia can’t get enough oxygen through the body. So they tire easily and they are often short of breath. Their skin and lips may look blue or gray. […] Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: […] Tricuspid atresia restricts blood flow from the heart to the lungs. The right lower heart chamber is small and underdeveloped. A life-threatening complication of tricuspid atresia is a lack of oxygen to the body’s tissues. This condition is called hypoxemia. […] Prompt treatment greatly improves the outcome for babies with tricuspid atresia. But complications may develop later in life. Complications of tricuspid atresia may include: Easy tiring during activity, Irregular heart rhythms, Kidney or liver disease, Heart failure.
  • #48 Tricuspid Atresia – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK554495/
    The majority of unoperated patients face a high risk of mortality within the first year of life. […] In the current era of early diagnosis and effective surgical interventions, individuals with tricuspid atresia commonly survive well into adulthood, maintaining good functional capacity. Operative mortality associated with the Fontan procedure is consistently below 2%. […] Surgical outcomes have significantly improved due to advancements in surgical techniques and innovations for addressing patients’ conditions. […] Tricuspid atresia can lead to various long-term complications, including Fontan-associated liver disease (characterized by liver fibrosis and cirrhosis), renal dysfunction, somatic growth problems, psychosocial and neurodevelopmental issues, and decreased exercise tolerance.
  • #49 Tricuspid atresia – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/tricuspid-atresia/symptoms-causes/syc-20368392
    Tricuspid atresia symptoms are usually seen soon after birth. Symptoms of tricuspid atresia may include: […] People with tricuspid atresia can’t get enough oxygen through the body. So they tire easily and they are often short of breath. Their skin and lips may look blue or gray. […] Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: […] Tricuspid atresia restricts blood flow from the heart to the lungs. The right lower heart chamber is small and underdeveloped. A life-threatening complication of tricuspid atresia is a lack of oxygen to the body’s tissues. This condition is called hypoxemia. […] Prompt treatment greatly improves the outcome for babies with tricuspid atresia. But complications may develop later in life. Complications of tricuspid atresia may include: Easy tiring during activity, Irregular heart rhythms, Kidney or liver disease, Heart failure.
  • #50 Tricuspid Valve Atresia | Norton Children’s Louisville, Ky.
    https://nortonchildrens.com/services/cardiology/conditions/congenital-heart-disease/tricuspid-atresia/
    The results for the three-stage surgical treatment for tricuspid atresia are generally good. Expected survival rates for children who complete all three stages of surgery are 75% to 95%, depending on the factors unique to each child and the care they receive. Long-term quality of life following the Fontan operation usually is good. Currently, the oldest patients who have had this procedure are age 30 and older. However, complications can occur, including heart rhythm issues that require medication or pacemaker placement. Lung issues also can occur, including a decrease in blood oxygen levels. Digestive issues can occur due to protein loss in the stool, which results in swelling and water retention. Some patients, despite doing well after surgeries, may need a heart or lung transplant later in life.
  • #51 Tricuspid Valve Atresia | Norton Children’s Louisville, Ky.
    https://nortonchildrens.com/services/cardiology/conditions/congenital-heart-disease/tricuspid-atresia/
    The results for the three-stage surgical treatment for tricuspid atresia are generally good. Expected survival rates for children who complete all three stages of surgery are 75% to 95%, depending on the factors unique to each child and the care they receive. Long-term quality of life following the Fontan operation usually is good. Currently, the oldest patients who have had this procedure are age 30 and older. However, complications can occur, including heart rhythm issues that require medication or pacemaker placement. Lung issues also can occur, including a decrease in blood oxygen levels. Digestive issues can occur due to protein loss in the stool, which results in swelling and water retention. Some patients, despite doing well after surgeries, may need a heart or lung transplant later in life.
  • #52 Tricuspid Atresia – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK554495/
    The majority of unoperated patients face a high risk of mortality within the first year of life. […] In the current era of early diagnosis and effective surgical interventions, individuals with tricuspid atresia commonly survive well into adulthood, maintaining good functional capacity. Operative mortality associated with the Fontan procedure is consistently below 2%. […] Surgical outcomes have significantly improved due to advancements in surgical techniques and innovations for addressing patients’ conditions. […] Tricuspid atresia can lead to various long-term complications, including Fontan-associated liver disease (characterized by liver fibrosis and cirrhosis), renal dysfunction, somatic growth problems, psychosocial and neurodevelopmental issues, and decreased exercise tolerance.
  • #53 Tricuspid atresia – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/tricuspid-atresia/symptoms-causes/syc-20368392
    Tricuspid atresia symptoms are usually seen soon after birth. Symptoms of tricuspid atresia may include: […] People with tricuspid atresia can’t get enough oxygen through the body. So they tire easily and they are often short of breath. Their skin and lips may look blue or gray. […] Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: […] Tricuspid atresia restricts blood flow from the heart to the lungs. The right lower heart chamber is small and underdeveloped. A life-threatening complication of tricuspid atresia is a lack of oxygen to the body’s tissues. This condition is called hypoxemia. […] Prompt treatment greatly improves the outcome for babies with tricuspid atresia. But complications may develop later in life. Complications of tricuspid atresia may include: Easy tiring during activity, Irregular heart rhythms, Kidney or liver disease, Heart failure.
  • #54 Tricuspid Atresia – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK554495/
    The majority of unoperated patients face a high risk of mortality within the first year of life. […] In the current era of early diagnosis and effective surgical interventions, individuals with tricuspid atresia commonly survive well into adulthood, maintaining good functional capacity. Operative mortality associated with the Fontan procedure is consistently below 2%. […] Surgical outcomes have significantly improved due to advancements in surgical techniques and innovations for addressing patients’ conditions. […] Tricuspid atresia can lead to various long-term complications, including Fontan-associated liver disease (characterized by liver fibrosis and cirrhosis), renal dysfunction, somatic growth problems, psychosocial and neurodevelopmental issues, and decreased exercise tolerance.
  • #55 Tricuspid Valve Atresia | Norton Children’s Louisville, Ky.
    https://nortonchildrens.com/services/cardiology/conditions/congenital-heart-disease/tricuspid-atresia/
    The results for the three-stage surgical treatment for tricuspid atresia are generally good. Expected survival rates for children who complete all three stages of surgery are 75% to 95%, depending on the factors unique to each child and the care they receive. Long-term quality of life following the Fontan operation usually is good. Currently, the oldest patients who have had this procedure are age 30 and older. However, complications can occur, including heart rhythm issues that require medication or pacemaker placement. Lung issues also can occur, including a decrease in blood oxygen levels. Digestive issues can occur due to protein loss in the stool, which results in swelling and water retention. Some patients, despite doing well after surgeries, may need a heart or lung transplant later in life.
  • #56 Tricuspid atresia – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/tricuspid-atresia/symptoms-causes/syc-20368392
    Tricuspid atresia symptoms are usually seen soon after birth. Symptoms of tricuspid atresia may include: […] People with tricuspid atresia can’t get enough oxygen through the body. So they tire easily and they are often short of breath. Their skin and lips may look blue or gray. […] Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: […] Tricuspid atresia restricts blood flow from the heart to the lungs. The right lower heart chamber is small and underdeveloped. A life-threatening complication of tricuspid atresia is a lack of oxygen to the body’s tissues. This condition is called hypoxemia. […] Prompt treatment greatly improves the outcome for babies with tricuspid atresia. But complications may develop later in life. Complications of tricuspid atresia may include: Easy tiring during activity, Irregular heart rhythms, Kidney or liver disease, Heart failure.
  • #57 Tricuspid Atresia
    https://healthlibrary.brighamandwomens.org/library/TestsProcedures/Cardiovascular/90,P01819
    Heart rhythm problems (arrhythmias) […] Less ability to exercise […] Heart failure […] Poor growth and development […] Death. […] Babies will have a blue color to their skin (cyanosis) after the first two surgeries, or until the final Fontan procedure is done. Your child may grow and develop slowly because of decreased oxygen in the blood. After the Fontan procedure, when oxygen levels get better, you will likely see large improvements in your child’s growth and development.
  • #58 Tricuspid Valve Atresia | Norton Children’s Louisville, Ky.
    https://nortonchildrens.com/services/cardiology/conditions/congenital-heart-disease/tricuspid-atresia/
    The results for the three-stage surgical treatment for tricuspid atresia are generally good. Expected survival rates for children who complete all three stages of surgery are 75% to 95%, depending on the factors unique to each child and the care they receive. Long-term quality of life following the Fontan operation usually is good. Currently, the oldest patients who have had this procedure are age 30 and older. However, complications can occur, including heart rhythm issues that require medication or pacemaker placement. Lung issues also can occur, including a decrease in blood oxygen levels. Digestive issues can occur due to protein loss in the stool, which results in swelling and water retention. Some patients, despite doing well after surgeries, may need a heart or lung transplant later in life.
  • #59 About Tricuspid Atresia | Congenital Heart Defects (CHDs) | CDC
    https://www.cdc.gov/heart-defects/about/tricuspid-atresia.html
    Babies born with tricuspid atresia will show symptoms at birth or very soon afterwards. They may have a bluish skin color, called cyanosis, because their blood doesn’t carry enough oxygen. Infants with tricuspid atresia can have additional symptoms such as: […] Babies born with tricuspid atresia will show symptoms at birth or very soon afterwards. During a physical examination, a doctor can see the symptom or hear a heart murmur when listening with a stethoscope. A heart murmur is an abnormal „whooshing” sound caused by blood not flowing properly. […] Infants who have these surgeries are not cured; they might have lifelong complications. If the tricuspid atresia is very complex, or the heart becomes weak after the surgeries, a heart transplant might be needed. Children who receive a heart transplant will need to take medicines for the rest of their lives. The medicines help prevent rejection of the new heart.
  • #60 Tricuspid atresia – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/tricuspid-atresia/symptoms-causes/syc-20368392
    Tricuspid atresia symptoms are usually seen soon after birth. Symptoms of tricuspid atresia may include: […] People with tricuspid atresia can’t get enough oxygen through the body. So they tire easily and they are often short of breath. Their skin and lips may look blue or gray. […] Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: […] Tricuspid atresia restricts blood flow from the heart to the lungs. The right lower heart chamber is small and underdeveloped. A life-threatening complication of tricuspid atresia is a lack of oxygen to the body’s tissues. This condition is called hypoxemia. […] Prompt treatment greatly improves the outcome for babies with tricuspid atresia. But complications may develop later in life. Complications of tricuspid atresia may include: Easy tiring during activity, Irregular heart rhythms, Kidney or liver disease, Heart failure.
  • #61 Mayo Clinic Health Library – Tricuspid atresia | Swiss Medical Network
    https://www.swissmedical.net/en/healtcare-library/con-20316967
    People with tricuspid atresia can’t get enough oxygen through the body. So they tire easily and they are often short of breath. Their skin and lips may look blue or gray. […] Tricuspid atresia symptoms are usually seen soon after birth. Symptoms of tricuspid atresia may include: Blue or gray skin and lips due to low blood oxygen levels, Difficulty breathing, Tiring easily, especially during feedings, Slow growth and poor weight gain. […] Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: Fatigue and weakness, Shortness of breath, Swelling in the legs, ankles and feet, Swelling of the belly area, a condition called ascites, Sudden weight gain from a buildup of fluid. […] Tricuspid atresia restricts blood flow from the heart to the lungs. The right lower heart chamber is small and underdeveloped. A life-threatening complication of tricuspid atresia is a lack of oxygen to the body’s tissues. This condition is called hypoxemia.
  • #62 Tricuspid atresia history and symptoms – wikidoc
    https://www.wikidoc.org/index.php/Tricuspid_atresia_history_and_symptoms
    The patients commonly have a history of cyanosis and symptoms of heart failure from the birth time. […] Symptoms of tricuspid atresia in neonates may include the following: Central cyanosis in mucous membranes and tongue, Poor feeding and growth retardation, Difficulty in breathing, Rapid heartbeats, Rapid breathing. […] Symptoms of longstanding cyanosis and hyperviscosity syndrome as a result of secondary erythrocytosis in older children include the following: Headache, Alter mentation, Faintness, Dizziness, Visual disturbances, Paresthesia, Tinnitus, Myalgia.
  • #63 Tricuspid Atresia: Understanding a Congenital Heart Condition
    https://longmoreclinic.org/tricuspid-atresia-understanding-a-congenital-heart-condition/
    Tricuspid atresia requires specialized medical attention and, in many cases, surgical intervention. […] The symptoms of tricuspid atresia can vary depending on the severity of the condition and the presence of other heart defects. Newborns with tricuspid atresia often exhibit signs of cyanosis—a bluish discoloration of the skin and lips—due to inadequate oxygen supply. Other common symptoms include: Rapid Breathing: Infants may experience rapid breathing as their bodies attempt to compensate for the lack of oxygen. Poor Feeding: Difficulty feeding and tiring easily during feeding. Fatigue: Older children and adults with tricuspid atresia may experience fatigue and exercise intolerance due to inadequate oxygen supply. Clubbing: In some cases, the fingertips and nails may become clubbed, which is a sign of chronic low oxygen levels. […] If a newborn or child shows symptoms such as cyanosis, rapid breathing, or poor feeding, immediate medical attention is necessary. Early diagnosis and intervention are vital to prevent complications and improve outcomes.
  • #64 Tricuspid Atresia | Children’s Hospital of Philadelphia
    https://www.chop.edu/conditions-diseases/tricuspid-atresia
    Tricuspid atresia symptoms in children include: […] Blue or purple tint to lips, skin and nails (cyanosis) […] Heart murmur, or abnormal heart sound when a doctor listens with a stethoscope […] Shortness of breath […] Difficulty feeding […] Poor weight gain […] Fatigue […] Abnormally shaped fingertips, called clubbing. […] Because of enormous strides in medicine and technology, today many children born with tricuspid atresia go on to lead healthy, productive lives as adults. […] Though early outcomes for children with single ventricle heart defects after staged reconstruction have greatly improved over the years, the time between the Norwood procedure and the Glenn operation is a very vulnerable time for infants. […] Children with tricuspid atresia require life-long care by a cardiologist. Many remain on medications for life. Additional surgeries may be required. […] As patients with Fontan circulation get older, doctors are recognizing that, while some do fine, many experience complications. These complications can include lung, liver and gastrointestinal diseases.
  • #65 Tricuspid atresia in children – Children’s Health Cardiology
    https://www.childrens.com/specialties-services/conditions/tricuspid-atresia
    Children with tricuspid atresia can have any of the following problems with their heart: A missing tricuspid valve, A small right ventricle, A hole between the right atrium and left atrium, which lets blue and red blood mix inside the heart. […] These heart issues interrupt the normal flow of blood through your child’s heart, which can cause other health issues. […] A tricuspid atresia can cause your childs blood to flow in the wrong direction inside of their heart. […] What are the signs and symptoms of tricuspid atresia? Blue or purple body or tongue, Heart murmur, Shortness of breath, Difficulty feeding and poor weight gain, Fatigue, Abnormal shape of the fingertips (known as clubbing).
  • #66 Tricuspid Atresia: Background, Pathophysiology, Etiology
    https://emedicine.medscape.com/article/158359-overview
    Tricuspid atresia is the third most common form of cyanotic congenital heart disease, with a prevalence of 1.03 per 10,000 live births. The deformity consists of a complete lack of formation of the tricuspid valve with absence of direct connection between the right atrium and right ventricle. […] The anomaly is congenital and is evident at birth. […] Depending on the degree of obstruction and associated anomalies, tricuspid atresia may be lethal at birth. Without repair, the patient rarely survives to adulthood. […] The 1-year survival rate after the Fontan operation is 85%; the 5-year survival rate is 78%. Because the procedure eliminates cyanosis, polycythemia and left ventricular volume overload are relieved; therefore, this population can be expected to live longer.
  • #67 Tricuspid atresia history and symptoms – wikidoc
    https://www.wikidoc.org/index.php/Tricuspid_atresia_history_and_symptoms
    The patients commonly have a history of cyanosis and symptoms of heart failure from the birth time. […] Symptoms of tricuspid atresia in neonates may include the following: Central cyanosis in mucous membranes and tongue, Poor feeding and growth retardation, Difficulty in breathing, Rapid heartbeats, Rapid breathing. […] Symptoms of longstanding cyanosis and hyperviscosity syndrome as a result of secondary erythrocytosis in older children include the following: Headache, Alter mentation, Faintness, Dizziness, Visual disturbances, Paresthesia, Tinnitus, Myalgia.
  • #68 Tricuspid atresia – Symptoms & causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/tricuspid-atresia/symptoms-causes/syc-20368392
    Tricuspid atresia symptoms are usually seen soon after birth. Symptoms of tricuspid atresia may include: […] People with tricuspid atresia can’t get enough oxygen through the body. So they tire easily and they are often short of breath. Their skin and lips may look blue or gray. […] Some people with tricuspid atresia also develop symptoms of heart failure. Heart failure symptoms include: […] Tricuspid atresia restricts blood flow from the heart to the lungs. The right lower heart chamber is small and underdeveloped. A life-threatening complication of tricuspid atresia is a lack of oxygen to the body’s tissues. This condition is called hypoxemia. […] Prompt treatment greatly improves the outcome for babies with tricuspid atresia. But complications may develop later in life. Complications of tricuspid atresia may include: Easy tiring during activity, Irregular heart rhythms, Kidney or liver disease, Heart failure.
  • #69 Tricuspid Atresia: Understanding a Congenital Heart Condition
    https://longmoreclinic.org/tricuspid-atresia-understanding-a-congenital-heart-condition/
    Tricuspid atresia requires specialized medical attention and, in many cases, surgical intervention. […] The symptoms of tricuspid atresia can vary depending on the severity of the condition and the presence of other heart defects. Newborns with tricuspid atresia often exhibit signs of cyanosis—a bluish discoloration of the skin and lips—due to inadequate oxygen supply. Other common symptoms include: Rapid Breathing: Infants may experience rapid breathing as their bodies attempt to compensate for the lack of oxygen. Poor Feeding: Difficulty feeding and tiring easily during feeding. Fatigue: Older children and adults with tricuspid atresia may experience fatigue and exercise intolerance due to inadequate oxygen supply. Clubbing: In some cases, the fingertips and nails may become clubbed, which is a sign of chronic low oxygen levels. […] If a newborn or child shows symptoms such as cyanosis, rapid breathing, or poor feeding, immediate medical attention is necessary. Early diagnosis and intervention are vital to prevent complications and improve outcomes.
  • #70 Tricuspid atresia – Diagnosis & treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/tricuspid-atresia/diagnosis-treatment/drc-20368416
    Tricuspid atresia may be diagnosed during a routine pregnancy ultrasound before a baby is born. […] After birth, a health care provider immediately examines the baby and listens to the baby’s heart and lungs. The care provider might suspect a heart problem such as tricuspid atresia if a baby has blue or gray skin, trouble breathing, or an irregular heart sound called a heart murmur. Changes in blood flow to and from the heart can cause a heart murmur. […] There’s no way to replace a tricuspid valve in tricuspid atresia. If your child has tricuspid atresia, several surgeries are often done to improve blood flow through the heart and to the lungs. Medications are used to manage symptoms. […] A baby with tricuspid atresia often needs several heart surgeries or procedures. Some of them are temporary fixes to quickly improve blood flow before a more permanent procedure can be done.
  • #71 Tricuspid atresia Information | Mount Sinai – New York
    https://www.mountsinai.org/health-library/diseases-conditions/tricuspid-atresia
    Tricuspid atresia is a type of heart disease that is present at birth (congenital heart disease), in which the tricuspid heart valve is missing or abnormally developed. The defect blocks blood flow from the right atrium to the right ventricle. Other heart or vessel defects are usually present at the same time. […] Symptoms include: Bluish color to the skin (cyanosis) due to low oxygen level in the blood, Fast breathing, Fatigue, Poor growth, Shortness of breath. […] This condition may be discovered during routine prenatal ultrasound imaging or when the baby is examined after birth. Bluish skin is present at birth. A heart murmur is often present at birth and may increase in loudness over several months. […] In most cases, surgery will improve the condition.
  • #72 Tricuspid Atresia | Heart Defects | NCBDDD | CDC
    http://med.iiab.me/modules/en-cdc/www.cdc.gov/ncbddd/heartdefects/tricuspid-atresia.html
    Tricuspid atresia is a critical congenital heart defect (critical CHD) that also can be detected with newborn screening using pulse oximetry (also known as pulse ox). Pulse oximetry is a simple, painless bedside test to estimate the amount of oxygen in a babys blood. The test is done using a machine called a pulse oximeter, with sensors placed on the babys skin. Low levels of oxygen in the blood can be a sign of a critical CHD. Newborn screening using pulse oximetry can identify some infants with a critical CHD, like tricuspid atresia, before they show any symptoms.
  • #73 Tricuspid Valve Atresia | Norton Children’s Louisville, Ky.
    https://nortonchildrens.com/services/cardiology/conditions/congenital-heart-disease/tricuspid-atresia/
    The results for the three-stage surgical treatment for tricuspid atresia are generally good. Expected survival rates for children who complete all three stages of surgery are 75% to 95%, depending on the factors unique to each child and the care they receive. Long-term quality of life following the Fontan operation usually is good. Currently, the oldest patients who have had this procedure are age 30 and older. However, complications can occur, including heart rhythm issues that require medication or pacemaker placement. Lung issues also can occur, including a decrease in blood oxygen levels. Digestive issues can occur due to protein loss in the stool, which results in swelling and water retention. Some patients, despite doing well after surgeries, may need a heart or lung transplant later in life.
  • #74 Tricuspid atresia
    https://www.aboutkidshealth.ca/tricuspid-atresia
    Children with tricuspid atresia are usually cyanotic at birth or shortly after, and have congestive heart failure. […] For children with this condition, outcomes are quite good through the staged repair, with survival at 75% to 95%. In some cases, arrhythmias can develop later in life, as can lung problems.
  • #75 Tricuspid atresia – Diagnosis & treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/tricuspid-atresia/diagnosis-treatment/drc-20368416
    After treatment, babies with tricuspid atresia need regular health checkups, ideally with a children’s doctor trained in congenital heart conditions. […] Adults treated for tricuspid atresia also need lifelong checkups, preferably with a doctor trained in adult congenital heart conditions. […] If your child has tricuspid atresia, lifestyle changes may be recommended to keep the heart healthy and prevent complications. […] If you have tricuspid atresia and are pregnant or hoping to be, consider talking to an adult congenital heart disease specialist and a maternal-fetal medicine specialist. During pregnancy, it’s important to receive care from a provider who specializes in pregnancies in those with congenital heart disease. […] Pregnancy is considered high risk for those who have had a Fontan procedure. If you have a history of heart failure, you may be discouraged from becoming pregnant.