Materiały źródłowe

• #1 Asthma – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/asthma/diagnosis-treatment/drc-20369660

  Prevention and long-term control are key to stopping asthma attacks before they start. Treatment usually involves learning to recognize your triggers, taking steps to avoid triggers and tracking your breathing to make sure your medications are keeping symptoms under control. In case of an asthma flare-up, you may need to use a quick-relief inhaler. […] The right medications for you depend on a number of things your age, symptoms, asthma triggers and what works best to keep your asthma under control. […] Preventive, long-term control medications reduce the swelling (inflammation) in your airways that leads to symptoms. Quick-relief inhalers (bronchodilators) quickly open swollen airways that are limiting breathing. In some cases, allergy medications are necessary. […] Long-term asthma control medications, generally taken daily, are the cornerstone of asthma treatment. These medications keep asthma under control on a day-to-day basis and make it less likely you’ll have an asthma attack.

• #2 Patient education: Asthma treatment in adolescents and adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/asthma-treatment-in-adolescents-and-adults-beyond-the-basics

  Patient education: Asthma treatment in adolescents and adults (Beyond the Basics) […] ASTHMA TREATMENT OVERVIEW […] Living with asthma can be challenging, but it is usually possible to manage it successfully with medications and other measures. The goals of asthma treatment are to control symptoms as well as possible and prevent asthma attacks (also called „exacerbations”). […] The approach to asthma treatment depends on the frequency and severity of your symptoms, including asthma attacks, as well as your personal preferences and risk factors. Good asthma control is the goal of asthma management and is achievable in the great majority of patients. […] There are several things you can do to keep your asthma well controlled. These include learning about your condition, understanding how and when to use each of your medications (and when to seek emergency help), avoiding things that trigger or make your symptoms worse, keeping track of your symptoms, and seeing your doctor regularly for monitoring.

• #3 How is asthma treated? – National Asthma Council Australia

  https://www.nationalasthma.org.au/understanding-asthma/how-is-asthma-managed

  Medicines are essential for managing asthma. Everyone with asthma should have their own up-to-date written asthma action plan with instructions on what to do when symptoms worsen. […] The main aims of asthma treatment are: to keep lungs as healthy as possible, to keep symptoms under control, to stop asthma from interfering with school, work or play, to prevent flare-ups or attacks. […] The two main types of asthma medicines are relievers and preventers. Every child, adolescent or adult with asthma needs to have a reliever inhaler (e.g. puffer) available at all times, so they can use straight away if they have asthma symptoms. […] Most adults and adolescents, and some children, also need to take daily preventer treatment to reduce their risk of flare-ups (attacks). Most preventers contain inhaled corticosteroids a type of medicine that soothes inflammation inside the lungs.

• #4 An overview of asthma management in children and adults – UpToDate

  https://www.uptodate.com/contents/an-overview-of-asthma-management

  INTRODUCTION […] The main goals of asthma management are to optimize control of asthma symptoms, reduce the risk of asthma exacerbations, and preserve lung function while minimizing medication adverse effects. It is expected that a person with well-controlled asthma should be able to participate in normal daily activities including sleep, work, school, play, and sports without limitation due to breathing. The four essential components of asthma management are patient education, minimizing exposure to asthma triggers, monitoring for changes in symptoms or lung function, and pharmacologic therapy. This overview topic presents the goals and components of asthma management. It is applicable to both children and adults. The recommendations are based upon major published asthma guidelines. […] […] […] Treatment of severe asthma in adolescents and adults […] […] […] Indications, dosing, and adverse effects of biologic agents used for severe asthma.

• #5 Patient education: Asthma treatment in adolescents and adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/asthma-treatment-in-adolescents-and-adults-beyond-the-basics

  Patient education: Asthma treatment in adolescents and adults (Beyond the Basics) […] ASTHMA TREATMENT OVERVIEW […] Living with asthma can be challenging, but it is usually possible to manage it successfully with medications and other measures. The goals of asthma treatment are to control symptoms as well as possible and prevent asthma attacks (also called „exacerbations”). […] The approach to asthma treatment depends on the frequency and severity of your symptoms, including asthma attacks, as well as your personal preferences and risk factors. Good asthma control is the goal of asthma management and is achievable in the great majority of patients. […] There are several things you can do to keep your asthma well controlled. These include learning about your condition, understanding how and when to use each of your medications (and when to seek emergency help), avoiding things that trigger or make your symptoms worse, keeping track of your symptoms, and seeing your doctor regularly for monitoring.

• #6 Treatment strategies for asthma: reshaping the concept of asthma management

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7491342/

  Asthma treatment is based on a stepwise and control-based approach that involves an iterative cycle of assessment, adjustment of the treatment and review of the response aimed to minimize symptom burden and risk of exacerbations. […] Anti-inflammatory treatment is the mainstay of asthma management. […] Asthma treatment is based on a stepwise approach. The management of the patient is control-based; that is, it involves an iterative cycle of assessment (e.g. symptoms, risk factors, etc.), adjustment of treatment (i.e. pharmacological, non-pharmacological and treatment of modifiable risk factors) and review of the response (e.g. symptoms, side effects, exacerbations, etc.). […] Asthma control medications reduce airway inflammation and help to prevent asthma symptoms; among these, inhaled corticosteroids (ICS) are the mainstay in the treatment of asthma, whereas quick-relief (reliever) or rescue medicines quickly ease symptoms that may arise acutely.

• #7 Asthma – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/asthma/diagnosis-treatment/drc-20369660

  Prevention and long-term control are key to stopping asthma attacks before they start. Treatment usually involves learning to recognize your triggers, taking steps to avoid triggers and tracking your breathing to make sure your medications are keeping symptoms under control. In case of an asthma flare-up, you may need to use a quick-relief inhaler. […] The right medications for you depend on a number of things your age, symptoms, asthma triggers and what works best to keep your asthma under control. […] Preventive, long-term control medications reduce the swelling (inflammation) in your airways that leads to symptoms. Quick-relief inhalers (bronchodilators) quickly open swollen airways that are limiting breathing. In some cases, allergy medications are necessary. […] Long-term asthma control medications, generally taken daily, are the cornerstone of asthma treatment. These medications keep asthma under control on a day-to-day basis and make it less likely you’ll have an asthma attack.

• #8 Asthma medications: Know your options

  https://www.mayoclinic.org/diseases-conditions/asthma/in-depth/asthma-medications/art-20045557

  Confused about your asthma medications? Here’s what you need to know to sort out the main classes and numerous subtypes of asthma drugs. The types and doses of asthma medications you need depend on your age, your symptoms, the severity of your asthma and medication side effects. Because your asthma can change over time, work closely with your health care provider to track your symptoms and adjust your asthma medications, if needed. Many people with asthma need to take long-term control medications daily, even when they don’t have symptoms. There are several types of long-term control medications, including the following. These anti-inflammatory drugs are the most effective and commonly used long-term control medications for asthma. They reduce swelling and tightening in your airways. You may need to use these medications for several months before you get their maximum benefit. Regular use of inhaled corticosteroids helps keep asthma attacks and other problems linked to poorly controlled asthma in check. In children, long-term use of inhaled corticosteroids can delay growth slightly, but the benefits of using these medications to maintain good asthma control generally outweigh the risks. Inhaled corticosteroids don’t generally cause serious side effects. When side effects occur, they can include mouth and throat irritation and oral yeast infections. If you’re using a metered dose inhaler, use a spacer and rinse your mouth with water after each use to reduce the amount of drug remaining in your mouth. These medications block the effects of leukotrienes, immune system chemicals that cause asthma symptoms. Leukotriene modifiers can help prevent symptoms for up to 24 hours. These bronchodilator medications open airways and reduce swelling for at least 12 hours. They’re used on a regular schedule to control moderate to severe asthma and to prevent nighttime symptoms. Although they’re effective, they’ve been linked to severe asthma attacks. For this reason, LABAs are taken only in combination with an inhaled corticosteroid. If an LABA cannot be used, a LAMA along with an inhaled corticosteroid can be an option. A LAMA can also be added to a LABA and inhaled corticosteroid if better control of your asthma is needed. These asthma medications sometimes called short-acting beta agonists (SABA) open the lungs by relaxing airway muscles. Often called rescue medications, they can ease worsening symptoms or stop an asthma attack in progress. They begin working within minutes and are effective for 4 to 6 hours. They’re not for daily use. If you need to use your inhaler more often than your health care provider recommends, your asthma is not under control and you may be increasing your risk of a serious asthma attack. Talk with your provider about adjusting your therapy. These medications may be taken usually for a limited time to treat severe asthma attacks. Oral corticosteroids can cause bothersome short-term side effects and more-serious side effects if they’re taken for a long period. Tracking symptoms and side effects and adjusting your treatment based on changes is key to keeping your asthma symptoms under control. With your health care provider, create a written detailed plan for taking long-term control medications and for managing an asthma attack. Then follow your plan.

• #9 Asthma medications: Know your options

  https://www.mayoclinic.org/diseases-conditions/asthma/in-depth/asthma-medications/art-20045557

  Confused about your asthma medications? Here’s what you need to know to sort out the main classes and numerous subtypes of asthma drugs. The types and doses of asthma medications you need depend on your age, your symptoms, the severity of your asthma and medication side effects. Because your asthma can change over time, work closely with your health care provider to track your symptoms and adjust your asthma medications, if needed. Many people with asthma need to take long-term control medications daily, even when they don’t have symptoms. There are several types of long-term control medications, including the following. These anti-inflammatory drugs are the most effective and commonly used long-term control medications for asthma. They reduce swelling and tightening in your airways. You may need to use these medications for several months before you get their maximum benefit. Regular use of inhaled corticosteroids helps keep asthma attacks and other problems linked to poorly controlled asthma in check. In children, long-term use of inhaled corticosteroids can delay growth slightly, but the benefits of using these medications to maintain good asthma control generally outweigh the risks. Inhaled corticosteroids don’t generally cause serious side effects. When side effects occur, they can include mouth and throat irritation and oral yeast infections. If you’re using a metered dose inhaler, use a spacer and rinse your mouth with water after each use to reduce the amount of drug remaining in your mouth. These medications block the effects of leukotrienes, immune system chemicals that cause asthma symptoms. Leukotriene modifiers can help prevent symptoms for up to 24 hours. These bronchodilator medications open airways and reduce swelling for at least 12 hours. They’re used on a regular schedule to control moderate to severe asthma and to prevent nighttime symptoms. Although they’re effective, they’ve been linked to severe asthma attacks. For this reason, LABAs are taken only in combination with an inhaled corticosteroid. If an LABA cannot be used, a LAMA along with an inhaled corticosteroid can be an option. A LAMA can also be added to a LABA and inhaled corticosteroid if better control of your asthma is needed. These asthma medications sometimes called short-acting beta agonists (SABA) open the lungs by relaxing airway muscles. Often called rescue medications, they can ease worsening symptoms or stop an asthma attack in progress. They begin working within minutes and are effective for 4 to 6 hours. They’re not for daily use. If you need to use your inhaler more often than your health care provider recommends, your asthma is not under control and you may be increasing your risk of a serious asthma attack. Talk with your provider about adjusting your therapy. These medications may be taken usually for a limited time to treat severe asthma attacks. Oral corticosteroids can cause bothersome short-term side effects and more-serious side effects if they’re taken for a long period. Tracking symptoms and side effects and adjusting your treatment based on changes is key to keeping your asthma symptoms under control. With your health care provider, create a written detailed plan for taking long-term control medications and for managing an asthma attack. Then follow your plan.

• #10 Asthma Treatments NYC | Mount Sinai – New York

  https://www.mountsinai.org/care/pulmonology/services/asthma/treatments

  Long-term medications, inhaled corticosteroids like Alvesco, Asmanex, Flovent, Pulmicort, and Qvar, are used by patients who have asthma symptoms at least twice a week or attacks at least once a year. These medications can temporarily reverse inflammation and symptoms. When taken regularly these medicines help prevent and control your asthma symptoms. […] Often times, your doctors will prescribe a combination of both short- and long-term medications to help you control your asthma. […] Other medications are taken orally, such as anti-leukotriene agents (Singulair, Accolate, Zyflo), and xanthines (Theophylline, Theodur, Slobid). Patients with severe allergic asthma may be treated with injectable medications (anti-IgE, Xolair). […] Mount Sinai Health System doctors and researchers continuously search for new asthma treatments. Currently, our researchers are investigating how to target pathways in the immune system through inhaled, oral, and injectable medications.

• #11 Asthma medications: Know your options

  https://www.mayoclinic.org/diseases-conditions/asthma/in-depth/asthma-medications/art-20045557

  Confused about your asthma medications? Here’s what you need to know to sort out the main classes and numerous subtypes of asthma drugs. The types and doses of asthma medications you need depend on your age, your symptoms, the severity of your asthma and medication side effects. Because your asthma can change over time, work closely with your health care provider to track your symptoms and adjust your asthma medications, if needed. Many people with asthma need to take long-term control medications daily, even when they don’t have symptoms. There are several types of long-term control medications, including the following. These anti-inflammatory drugs are the most effective and commonly used long-term control medications for asthma. They reduce swelling and tightening in your airways. You may need to use these medications for several months before you get their maximum benefit. Regular use of inhaled corticosteroids helps keep asthma attacks and other problems linked to poorly controlled asthma in check. In children, long-term use of inhaled corticosteroids can delay growth slightly, but the benefits of using these medications to maintain good asthma control generally outweigh the risks. Inhaled corticosteroids don’t generally cause serious side effects. When side effects occur, they can include mouth and throat irritation and oral yeast infections. If you’re using a metered dose inhaler, use a spacer and rinse your mouth with water after each use to reduce the amount of drug remaining in your mouth. These medications block the effects of leukotrienes, immune system chemicals that cause asthma symptoms. Leukotriene modifiers can help prevent symptoms for up to 24 hours. These bronchodilator medications open airways and reduce swelling for at least 12 hours. They’re used on a regular schedule to control moderate to severe asthma and to prevent nighttime symptoms. Although they’re effective, they’ve been linked to severe asthma attacks. For this reason, LABAs are taken only in combination with an inhaled corticosteroid. If an LABA cannot be used, a LAMA along with an inhaled corticosteroid can be an option. A LAMA can also be added to a LABA and inhaled corticosteroid if better control of your asthma is needed. These asthma medications sometimes called short-acting beta agonists (SABA) open the lungs by relaxing airway muscles. Often called rescue medications, they can ease worsening symptoms or stop an asthma attack in progress. They begin working within minutes and are effective for 4 to 6 hours. They’re not for daily use. If you need to use your inhaler more often than your health care provider recommends, your asthma is not under control and you may be increasing your risk of a serious asthma attack. Talk with your provider about adjusting your therapy. These medications may be taken usually for a limited time to treat severe asthma attacks. Oral corticosteroids can cause bothersome short-term side effects and more-serious side effects if they’re taken for a long period. Tracking symptoms and side effects and adjusting your treatment based on changes is key to keeping your asthma symptoms under control. With your health care provider, create a written detailed plan for taking long-term control medications and for managing an asthma attack. Then follow your plan.

• #12 The 2019 GINA Guidelines for Asthma Treatment in Adults

  https://www.uspharmacist.com/article/the-2019-gina-guidelines-for-asthma-treatment-in-adults

  Nonpharmacologic interventions for all asthma patients include breathing exercises, increased physical activity, incorporation of a healthy diet, and avoidance of exposure to smoke and other substances. […] Once a diagnosis of asthma has been made, an ICS-containing controller treatment should be initiated because of the greater improvement in lung function than when ICS controller treatment is not used. This is an important change in the 2019 GINA guidelines, as it was previously recommended to give newly diagnosed patients a SABA alone. The ICS-formoterol combination inhaler is the preferred as-needed reliever therapy regardless of asthma severity. […] GINA recommends the following asthma-treatment steps: Step 1: This step is advised for patients with mild asthma who have symptoms less than twice per month and no risk of exacerbations.

• #13 Asthma medications: Know your options

  https://www.mayoclinic.org/diseases-conditions/asthma/in-depth/asthma-medications/art-20045557

  Confused about your asthma medications? Here’s what you need to know to sort out the main classes and numerous subtypes of asthma drugs. The types and doses of asthma medications you need depend on your age, your symptoms, the severity of your asthma and medication side effects. Because your asthma can change over time, work closely with your health care provider to track your symptoms and adjust your asthma medications, if needed. Many people with asthma need to take long-term control medications daily, even when they don’t have symptoms. There are several types of long-term control medications, including the following. These anti-inflammatory drugs are the most effective and commonly used long-term control medications for asthma. They reduce swelling and tightening in your airways. You may need to use these medications for several months before you get their maximum benefit. Regular use of inhaled corticosteroids helps keep asthma attacks and other problems linked to poorly controlled asthma in check. In children, long-term use of inhaled corticosteroids can delay growth slightly, but the benefits of using these medications to maintain good asthma control generally outweigh the risks. Inhaled corticosteroids don’t generally cause serious side effects. When side effects occur, they can include mouth and throat irritation and oral yeast infections. If you’re using a metered dose inhaler, use a spacer and rinse your mouth with water after each use to reduce the amount of drug remaining in your mouth. These medications block the effects of leukotrienes, immune system chemicals that cause asthma symptoms. Leukotriene modifiers can help prevent symptoms for up to 24 hours. These bronchodilator medications open airways and reduce swelling for at least 12 hours. They’re used on a regular schedule to control moderate to severe asthma and to prevent nighttime symptoms. Although they’re effective, they’ve been linked to severe asthma attacks. For this reason, LABAs are taken only in combination with an inhaled corticosteroid. If an LABA cannot be used, a LAMA along with an inhaled corticosteroid can be an option. A LAMA can also be added to a LABA and inhaled corticosteroid if better control of your asthma is needed. These asthma medications sometimes called short-acting beta agonists (SABA) open the lungs by relaxing airway muscles. Often called rescue medications, they can ease worsening symptoms or stop an asthma attack in progress. They begin working within minutes and are effective for 4 to 6 hours. They’re not for daily use. If you need to use your inhaler more often than your health care provider recommends, your asthma is not under control and you may be increasing your risk of a serious asthma attack. Talk with your provider about adjusting your therapy. These medications may be taken usually for a limited time to treat severe asthma attacks. Oral corticosteroids can cause bothersome short-term side effects and more-serious side effects if they’re taken for a long period. Tracking symptoms and side effects and adjusting your treatment based on changes is key to keeping your asthma symptoms under control. With your health care provider, create a written detailed plan for taking long-term control medications and for managing an asthma attack. Then follow your plan.

• #14 Asthma: Updated Diagnosis and Management Recommendations from GINA | AAFP

  https://www.aafp.org/pubs/afp/issues/2020/0615/p762.html

  An inhaled low-dose ICS/formoterol combination used as needed is the preferred treatment in adults and adolescents. […] The guideline also strongly discourages the use of long-acting bronchodilators without an ICS because of increased risk of exacerbation. […] Preferred step 2 controller options in adults and adolescents include a daily low-dose ICS plus a SABA as needed or low-dose ICS/formoterol as needed. […] Options in adults and adolescents include low-dose ICS/long-acting beta2-agonist (LABA) as daily treatment with a SABA as needed, or low-dose ICS/formoterol as both daily treatment and as needed. […] Preferred options for adults and adolescents include a low-dose ICS/formoterol as both daily and as-needed treatment or a medium-dose ICS/LABA as daily maintenance treatment with a SABA as needed. […] Patients with persistent and severe symptoms despite optimal use of step 4 treatments should be referred for allergist evaluation and consideration of add-on treatments.

• #15 Asthma – Treatment and Action Plan | NHLBI, NIH

  https://www.nhlbi.nih.gov/health/asthma/treatment-action-plan

  Treatment for asthma usually depends on your age, how serious your symptoms are, and how your body responds to medicines. […] Your healthcare provider may adjust your treatment until your asthma symptoms are controlled. […] Quick-relief medicines, or relievers, help prevent or ease symptoms during an asthma attack. […] Your healthcare provider will probably prescribe a quick-relief inhaler for you to carry at all times. […] Your healthcare provider may prescribe controller medicines to take daily to help prevent asthma attacks and control symptoms. […] Corticosteroids (steroid hormone medicines) reduce inflammation in the body. […] Biologic medicines, such as benralizumab, may help with asthma that is difficult to control. […] Allergy shots, called subcutaneous immunotherapy (SCIT), turn down the body’s response to allergens.

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• #18 Asthma – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/asthma/diagnosis-treatment/drc-20369660

  Quick-relief (rescue) medications are used as needed for rapid, short-term symptom relief during an asthma attack. They may also be used before exercise if your doctor recommends it. […] Allergy medications may help if your asthma is triggered or worsened by allergies. […] This treatment is used for severe asthma that doesn’t improve with inhaled corticosteroids or other long-term asthma medications. […] Your treatment should be flexible and based on changes in your symptoms. […] Work with your doctor to create an asthma action plan that outlines in writing when to take certain medications or when to increase or decrease the dose of your medications based on your symptoms. […] Your doctor may also recommend tracking your asthma symptoms or using a peak flow meter on a regular basis to monitor how well your treatment is controlling your asthma.

• #19 Asthma medications: Know your options

  https://www.mayoclinic.org/diseases-conditions/asthma/in-depth/asthma-medications/art-20045557

  Confused about your asthma medications? Here’s what you need to know to sort out the main classes and numerous subtypes of asthma drugs. The types and doses of asthma medications you need depend on your age, your symptoms, the severity of your asthma and medication side effects. Because your asthma can change over time, work closely with your health care provider to track your symptoms and adjust your asthma medications, if needed. Many people with asthma need to take long-term control medications daily, even when they don’t have symptoms. There are several types of long-term control medications, including the following. These anti-inflammatory drugs are the most effective and commonly used long-term control medications for asthma. They reduce swelling and tightening in your airways. You may need to use these medications for several months before you get their maximum benefit. Regular use of inhaled corticosteroids helps keep asthma attacks and other problems linked to poorly controlled asthma in check. In children, long-term use of inhaled corticosteroids can delay growth slightly, but the benefits of using these medications to maintain good asthma control generally outweigh the risks. Inhaled corticosteroids don’t generally cause serious side effects. When side effects occur, they can include mouth and throat irritation and oral yeast infections. If you’re using a metered dose inhaler, use a spacer and rinse your mouth with water after each use to reduce the amount of drug remaining in your mouth. These medications block the effects of leukotrienes, immune system chemicals that cause asthma symptoms. Leukotriene modifiers can help prevent symptoms for up to 24 hours. These bronchodilator medications open airways and reduce swelling for at least 12 hours. They’re used on a regular schedule to control moderate to severe asthma and to prevent nighttime symptoms. Although they’re effective, they’ve been linked to severe asthma attacks. For this reason, LABAs are taken only in combination with an inhaled corticosteroid. If an LABA cannot be used, a LAMA along with an inhaled corticosteroid can be an option. A LAMA can also be added to a LABA and inhaled corticosteroid if better control of your asthma is needed. These asthma medications sometimes called short-acting beta agonists (SABA) open the lungs by relaxing airway muscles. Often called rescue medications, they can ease worsening symptoms or stop an asthma attack in progress. They begin working within minutes and are effective for 4 to 6 hours. They’re not for daily use. If you need to use your inhaler more often than your health care provider recommends, your asthma is not under control and you may be increasing your risk of a serious asthma attack. Talk with your provider about adjusting your therapy. These medications may be taken usually for a limited time to treat severe asthma attacks. Oral corticosteroids can cause bothersome short-term side effects and more-serious side effects if they’re taken for a long period. Tracking symptoms and side effects and adjusting your treatment based on changes is key to keeping your asthma symptoms under control. With your health care provider, create a written detailed plan for taking long-term control medications and for managing an asthma attack. Then follow your plan.

• #20 Asthma – quick-relief drugs : MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/patientinstructions/000008.htm

  Asthma quick-relief medicines work fast to control asthma symptoms. You take them when you are coughing, wheezing, having trouble breathing, or having an asthma attack. They are also called rescue medicines. […] Many of these medicines are called „bronchodilators” because they open (dilate) and help relax the muscles of your airways (bronchi). […] You and your health care provider can make a plan for the quick-relief medicines that work for you. This plan will include when you should take them and how much you should take. […] Short-acting beta-agonists are the most common quick-relief medicines for treating asthma attacks and are considered to be bronchodilators. […] They can be used just before exercising to help prevent asthma symptoms caused by exercise. […] Tell your provider if you are using quick-relief medicines twice a week or more to control your asthma symptoms. Your asthma may not be under control, and your provider may need to change your dose of daily control medicines. […] Your provider might prescribe oral steroids when you have an asthma attack that is not going away. These are medicines that you take by mouth as pills, capsules, or liquids. […] Oral steroids are not quick-relief medicines but are often given for 7 to 14 days when your symptoms flare-up.

• #21 Asthma Exacerbation in Adults – Treatment : Emergency Care BC

  https://emergencycarebc.ca/clinical_resource/clinical-summary/asthma-exacerbation-in-adults-treatment/

  Asthma Exacerbation in Adults – Treatment […] Recommended Treatment […] Standard Treatment […] Oxygen […] Maintain O2 Saturations >92%. […] Usually not necessary for mild or moderate exacerbations. […] Short Acting Beta Agonist (SABA) […] Metered Dose Inhaler (MDI) Salbutamol (100 mcg/puff) with spacer. […] 4 to 8 puffs q20 minutes x 3 doses, then every 1 to 4 hours prn. […] Nebulized Salbutamol 5-5mg in 3 mLs saline q20 minutes x 3 doses, then 2.5-10mg every 1 to 4 hours prn. […] If severe exacerbation – give more frequently or continuous. […] Anticholinergics […] Use alongside SABA for moderate or severe exacerbations. […] MDI Ipratropium bromide (20mcg/puff) with spacer. […] 4 to 8 puffs q 20 minutes x 3 doses, then prn. […] Nebulized Ipratropium bromide 500mcg (with salbutamol) q20 minutes x 3 doses, then q2-6 prn.

• #22 Asthma medications: Know your options

  https://www.mayoclinic.org/diseases-conditions/asthma/in-depth/asthma-medications/art-20045557

  Confused about your asthma medications? Here’s what you need to know to sort out the main classes and numerous subtypes of asthma drugs. The types and doses of asthma medications you need depend on your age, your symptoms, the severity of your asthma and medication side effects. Because your asthma can change over time, work closely with your health care provider to track your symptoms and adjust your asthma medications, if needed. Many people with asthma need to take long-term control medications daily, even when they don’t have symptoms. There are several types of long-term control medications, including the following. These anti-inflammatory drugs are the most effective and commonly used long-term control medications for asthma. They reduce swelling and tightening in your airways. You may need to use these medications for several months before you get their maximum benefit. Regular use of inhaled corticosteroids helps keep asthma attacks and other problems linked to poorly controlled asthma in check. In children, long-term use of inhaled corticosteroids can delay growth slightly, but the benefits of using these medications to maintain good asthma control generally outweigh the risks. Inhaled corticosteroids don’t generally cause serious side effects. When side effects occur, they can include mouth and throat irritation and oral yeast infections. If you’re using a metered dose inhaler, use a spacer and rinse your mouth with water after each use to reduce the amount of drug remaining in your mouth. These medications block the effects of leukotrienes, immune system chemicals that cause asthma symptoms. Leukotriene modifiers can help prevent symptoms for up to 24 hours. These bronchodilator medications open airways and reduce swelling for at least 12 hours. They’re used on a regular schedule to control moderate to severe asthma and to prevent nighttime symptoms. Although they’re effective, they’ve been linked to severe asthma attacks. For this reason, LABAs are taken only in combination with an inhaled corticosteroid. If an LABA cannot be used, a LAMA along with an inhaled corticosteroid can be an option. A LAMA can also be added to a LABA and inhaled corticosteroid if better control of your asthma is needed. These asthma medications sometimes called short-acting beta agonists (SABA) open the lungs by relaxing airway muscles. Often called rescue medications, they can ease worsening symptoms or stop an asthma attack in progress. They begin working within minutes and are effective for 4 to 6 hours. They’re not for daily use. If you need to use your inhaler more often than your health care provider recommends, your asthma is not under control and you may be increasing your risk of a serious asthma attack. Talk with your provider about adjusting your therapy. These medications may be taken usually for a limited time to treat severe asthma attacks. Oral corticosteroids can cause bothersome short-term side effects and more-serious side effects if they’re taken for a long period. Tracking symptoms and side effects and adjusting your treatment based on changes is key to keeping your asthma symptoms under control. With your health care provider, create a written detailed plan for taking long-term control medications and for managing an asthma attack. Then follow your plan.

• #23 Breathing a sigh of relief: A new therapy for asthma management | The University of Arizona Health Sciences

  https://healthsciences.arizona.edu/news/blog/breathing-a-sigh-of-relief-a-new-therapy-for-asthma-management

  People with asthma now have a way to manage their symptoms that is easier and more effective than traditional therapeutics. […] It involves using only one inhaler to simultaneously deliver two types of medications in what is called SMART therapy, or single maintenance and reliever therapy, and it is endorsed by national boards and global organizations for moderate to severe asthma. […] Traditionally, people with asthma are prescribed one maintenance inhaler for daily doses of an anti-inflammatory medicine and then one rescue, or reliever, inhaler to open the airways when needed. […] With SMART, people with moderate to severe asthma typically use one inhaler with both medications twice a day, and then additionally if needed. An anti-inflammatory corticosteroid serves as an ongoing preventive treatment, and a long-acting beta-agonist functions as a quick relief therapy when people are having symptoms.

• #24 How Is Asthma Treated?

  https://aafa.org/asthma/asthma-treatment/

  Asthma treatments work in these ways: They relax the muscles that tighten around the airways. They relieve the squeeze. They can be short- or long-acting. By opening the airways, they help remove and reduce mucus. These medicines are bronchodilators or beta agonists. They reduce the swelling and mucus inside the airways. These medicines are anti-inflammatories (steroidal and non-steroidal). […] Biologics are shots or infusions given every few weeks. They work by targeting a cell or protein in your body to prevent airway swelling. They are for moderate-to-severe asthma that is hard to treat with ICS and/or other medicines, or people with asthma dependent on OCS. […] The 2020 Focused Updates to the Asthma Management Guidelines recommends single maintenance and reliever therapy, also known as SMART. SMART uses one inhaler that has two medicines (combination medicine) as a quick-relief and controller medicine.

• #25 SMART Therapy for Asthma

  https://www.aaaai.org/tools-for-the-public/conditions-library/asthma/smart

  SMART for asthma […] SMART or MART therapy stands for „Single Maintenance and Reliever Therapy.” It uses one inhaler that combines two medicines: an inhaled corticosteroid (ICS) to treat inflammation, and formoterol, a long-acting beta-2 agonist (LABA) to help open up the lungs. You use this inhaler every day to control asthma and also for quick relief when you need it. […] The Global Initiative for Asthma (GINA) and the National Asthma Education and Prevention Program (NAEPP) recommend this approach for patients with moderate to severe asthma. […] SMART therapy combines two medications with different mechanisms of action in one inhaler: Inhaled corticosteroid: helps reduce the ongoing inflammation in the airway, which addresses the root cause of asthma. Long-acting beta-2 agonist: a bronchodilator that quickly opens the airway and lasts approximately 12 hours which provides symptom relief.

• #26 SMART Therapy for Asthma

  https://www.aaaai.org/tools-for-the-public/conditions-library/asthma/smart

  SMART therapy combines ICS and a rapid-onset LABA. The studies for SMART therapy were conducted using formoterol, and it is the only LABA approved for this type of therapy. […] Fewer Severe Asthma Attacks: SMART therapy helps prevent serious asthma attacks better than using separate inhalers for daily control and quick relief. Less Corticosteroid Use: It can reduce the amount of corticosteroids you need, which can help lower the risk of side effects. […] Although several studies support the implementation of SMART therapy in patients with moderate to severe asthma, the Food and Drug Administration (FDA) has not approved the use of ICS-formoterol inhalers as rescue inhalers or as part of SMART therapy in the United States. […] The hope is that GINA and NAEPP’s evidence-based recommendations will push policymakers and health insurance companies to review their current indications, formularies and inhaler quantity limits. […] An allergy and immunology specialist physician is a trained expert in asthma and can develop an individualized therapy plan for your asthma.

• #27 SMART Therapy for Asthma – Allergy & Asthma Network

  https://allergyasthmanetwork.org/news/asthma-smart-therapy/

  SMART therapy stands for Single Maintenance and Reliever Therapy. It is sometimes also called MART therapy, for Maintenance and Reliever Therapy, but SMART and MART are the same. […] SMART therapy is for patients with moderate to severe asthma who need a combination treatment. This combined treatment consists of an inhaled corticosteroid and an inhaled long-acting beta-2 agonist (LABA). […] In asthma guidelines for SMART therapy, the budesonide/formoterol combination is the recommended first treatment for moderate to severe asthma. […] SMART therapy allows people with asthma to use just one medication to control asthma symptoms. They use this single medication for both maintenance and reliever therapy. […] Under asthma guidelines, SMART therapy is recommended for people with moderate to severe asthma, including children ages 5 and older.

• #28 Treatment strategies for asthma: reshaping the concept of asthma management

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7491342/

  The concomitant administration of an as-needed bronchodilator and ICS would provide rapid relief while administering anti-inflammatory therapy. […] The combination of an ICS and a LABA (budesonide/formoterol) in one inhaler for both maintenance and reliever therapy is even more effective than higher doses of maintenance ICS and LABA. […] A growing body of evidence shows that an anti-inflammatory reliever strategy, when compared with all other strategies with SABA reliever, consistently reduces the rate of exacerbations across all levels of asthma severity. […] The 2019 GINA has introduced key changes in the treatment of mild asthma: for safety reasons, asthmatic adults and adolescents should receive ICS-containing controller treatment instead of the SABA-only treatment, which is no longer recommended.

• #29 Asthma Medication and Treatment

  https://allergyasthmanetwork.org/what-is-asthma/how-is-asthma-treated/

  Combination medications combine two or even three medications into one inhaler. The devices may contain an anti-inflammatory inhaled corticosteroids, a SABA, LABA or LAMA. Combination medications are typically used daily. […] Biologic medications target cells, pathways and proteins that cause inflammation in the body. These medications focus on treating the source of symptoms rather than the symptoms themselves. […] Bronchial thermoplasty is an outpatient surgical procedure. It is for adults ages 18 and older with poor asthma control. […] If you have severe and difficult-to-control asthma, talk with your doctor to determine if bronchial thermoplasty is right for you. […] Follow the asthma treatment plan prescribed by your healthcare provider and be aware of your triggers. […] Asthma is a condition that requires constant attention. Thats why you need an Asthma Action Plan a personalized treatment plan. It is important for disease control and it can help prevent asthma attacks.

• #30 Biologic Therapy for Severe Asthma: Risks & Results

  https://my.clevelandclinic.org/health/treatments/17711-biologic-therapy-for-severe-asthma

  Biologic therapy for asthma targets different parts of your immune system to help people who have moderate to severe asthma that inhalers and other medicines cant manage. Side effects may include headache, joint and back pain and a reaction around the injection site. Results may take a few weeks or months. […] Biologic therapy for asthma is a newer treatment for moderate to severe asthma. Many people can manage asthma with inhalers. However, some people with moderate to severe asthma have frequent symptoms or flare-ups despite proper use of inhaled therapy. Biologic therapy works by targeting different antibodies, cells or molecules that cause asthma. Biologics may decrease flare-ups, improve quality of life and some can even improve lung function. […] Healthcare providers administer biologics either as a shot (subcutaneous injection) or intravenous (IV) infusion. During an IV infusion, a healthcare provider will use a needle to deliver the medication directly into a vein, usually in your arm.

• #31 Biologic Therapy for Severe Asthma: Risks & Results

  https://my.clevelandclinic.org/health/treatments/17711-biologic-therapy-for-severe-asthma

  Biologics arent a standalone medication. You should take them along with other types of asthma treatments, including allergy medications, allergy shots (immunotherapy), and asthma inhalers. […] A healthcare provider may recommend biologic therapy to treat asthma if you cant manage your symptoms despite using your asthma medications properly. […] The following biologic therapy drugs for asthma that have U.S. Food and Drug Administration (FDA) approval include Omalizumab, Mepolizumab, Reslizumab, Benralizumab, Dupilumab, and Tezepelumab. […] The primary benefits of biologic therapy for asthma are that they reduce inflammation in your airways and improve your asthma symptoms. […] In general, biologics for asthma are safe. But like all medications, biologics do have potential risks. […] Potential biologics risks or side effects include severe allergic reactions and greater risk of parasitic infections.

• #32 Difficult-to-Treat and Severe Asthma: Management Strategies | AAFP

  https://www.aafp.org/pubs/afp/issues/2021/0301/p286.html

  Type 2 inflammation occurs in 50% of people with severe asthma and responds to newer biologic agents. It is identified by elevated eosinophils in the blood or sputum or elevated ferrous nitrous oxide inhalation. Biologic therapy may be considered in patients with type 2 inflammation if it is available and affordable. […] Therapies that target type 2 inflammation pathways are omalizumab (Xolair), mepolizumab (Nucala), reslizumab (Cinqair), dupilumab (Dupixent), and benralizumab (Fasenra). […] A Cochrane review found that bronchial thermoplasty modestly improves quality of life and lowers rates of acute asthma exacerbations in patients with moderate to severe asthma but has no significant effect on asthma control scores. […] A study of vitamin D supplementation in adults with asthma, most of whom were deficient in vitamin D, did not show that it prevents exacerbations or improves clinical outcomes.

• #33 Biologic Therapy for Severe Asthma: Risks & Results

  https://my.clevelandclinic.org/health/treatments/17711-biologic-therapy-for-severe-asthma

  It depends. Your body is unique, and how it responds to biologics may be different from others. Some people may notice their symptoms start to improve within a week or two. For others, it may take as long as four to six months. […] Biological therapy for asthma is a relatively new, effective treatment for moderate to severe asthma. It doesnt just treat your asthma symptoms, but helps to decrease inflammation in your airways. It may take up to several months to notice an improvement in your symptoms.

• #34 First new asthma attack treatment in 50 years

  https://www.bbc.com/news/articles/cev93777g79o

  Researchers say they have found the first new treatment for asthma attacks in 50 years. […] The injection dampens part of the immune system that can go into overdrive in flare-ups of both asthma and a lung condition called chronic obstructive pulmonary disease (COPD). […] Benralizumab is already used in the most severe cases, but the latest research suggests it could be used routinely for around two million attacks in the UK each year. […] The research team at King’s College London said the drug was a „game-changer” that could „revolutionise” care. […] „Now we can see there are different patterns of inflammation, we can be smarter and get the right treatment, to the right patient, at the right time,” said Prof Mona Bafadhel, from King’s. […] Benralizumab targets a type of white blood cell – called an eosinophil – that can cause inflammation and damage in the lungs.

• #35 Asthma Medication and Treatment

  https://allergyasthmanetwork.org/what-is-asthma/how-is-asthma-treated/

  Combination medications combine two or even three medications into one inhaler. The devices may contain an anti-inflammatory inhaled corticosteroids, a SABA, LABA or LAMA. Combination medications are typically used daily. […] Biologic medications target cells, pathways and proteins that cause inflammation in the body. These medications focus on treating the source of symptoms rather than the symptoms themselves. […] Bronchial thermoplasty is an outpatient surgical procedure. It is for adults ages 18 and older with poor asthma control. […] If you have severe and difficult-to-control asthma, talk with your doctor to determine if bronchial thermoplasty is right for you. […] Follow the asthma treatment plan prescribed by your healthcare provider and be aware of your triggers. […] Asthma is a condition that requires constant attention. Thats why you need an Asthma Action Plan a personalized treatment plan. It is important for disease control and it can help prevent asthma attacks.

• #36 Asthma: Symptoms, Treatment, and More

  https://www.healthline.com/health/asthma

  Long-term asthma control medications: You can take these medications daily to help reduce the number and severity of asthma symptoms. But they dont manage the immediate symptoms of an attack. […] Doctors use biologics to treat severe asthma that doesnt respond to other medications or to treatment by trigger management. […] Bronchial thermoplasty: This treatment uses an electrode to heat the airways inside your lungs, helping to reduce the size of the surrounding muscle and prevent it from tightening. […] You can help prevent exacerbations by taking medications that help manage your asthma symptoms. […] If you need to use quick-relief medications frequently, ask your doctor about another type of medication for long-term asthma control. […] Your doctor can help you create an asthma action plan so you know which treatments to use and when.

• #37 Difficult-to-Treat and Severe Asthma: Management Strategies | AAFP

  https://www.aafp.org/pubs/afp/issues/2021/0301/p286.html

  Bronchial thermoplasty modestly improves quality of life and lowers rates of asthma exacerbation in patients with moderate to severe asthma. […] Difficult-to-treat asthma requires a coordinated holistic approach that addresses the disease and its impact on patients’ lives. Recent advances have expanded the therapeutic options. […] The third step is to optimize management. Patients should be educated on self-assessment of asthma control, understanding asthma medications, proper inhaler technique, and creating a home action plan. Asthma therapy should include a high-dose inhaled corticosteroid plus a long-acting beta agonist (LABA) and rescue therapy. Nonbiologic add-on therapies, such as a long-acting muscarinic agent (LAMA) or leukotriene receptor antagonist, should be considered. […] The clinical response to treatment should be assessed after three to six months. If the asthma is still uncontrolled or therapy cannot be stepped down, the asthma can be reclassified as severe and the patient referred to an allergist or pulmonologist.

• #38 Difficult-to-Treat and Severe Asthma: Management Strategies | AAFP

  https://www.aafp.org/pubs/afp/issues/2021/0301/p286.html

  Type 2 inflammation occurs in 50% of people with severe asthma and responds to newer biologic agents. It is identified by elevated eosinophils in the blood or sputum or elevated ferrous nitrous oxide inhalation. Biologic therapy may be considered in patients with type 2 inflammation if it is available and affordable. […] Therapies that target type 2 inflammation pathways are omalizumab (Xolair), mepolizumab (Nucala), reslizumab (Cinqair), dupilumab (Dupixent), and benralizumab (Fasenra). […] A Cochrane review found that bronchial thermoplasty modestly improves quality of life and lowers rates of acute asthma exacerbations in patients with moderate to severe asthma but has no significant effect on asthma control scores. […] A study of vitamin D supplementation in adults with asthma, most of whom were deficient in vitamin D, did not show that it prevents exacerbations or improves clinical outcomes.

• #39 Treatment strategies for asthma: reshaping the concept of asthma management

  https://pmc.ncbi.nlm.nih.gov/articles/PMC7491342/

  Asthma treatment is based on a stepwise and control-based approach that involves an iterative cycle of assessment, adjustment of the treatment and review of the response aimed to minimize symptom burden and risk of exacerbations. […] Anti-inflammatory treatment is the mainstay of asthma management. […] Asthma treatment is based on a stepwise approach. The management of the patient is control-based; that is, it involves an iterative cycle of assessment (e.g. symptoms, risk factors, etc.), adjustment of treatment (i.e. pharmacological, non-pharmacological and treatment of modifiable risk factors) and review of the response (e.g. symptoms, side effects, exacerbations, etc.). […] Asthma control medications reduce airway inflammation and help to prevent asthma symptoms; among these, inhaled corticosteroids (ICS) are the mainstay in the treatment of asthma, whereas quick-relief (reliever) or rescue medicines quickly ease symptoms that may arise acutely.

• #40 The 2019 GINA Guidelines for Asthma Treatment in Adults

  https://www.uspharmacist.com/article/the-2019-gina-guidelines-for-asthma-treatment-in-adults

  Nonpharmacologic interventions for all asthma patients include breathing exercises, increased physical activity, incorporation of a healthy diet, and avoidance of exposure to smoke and other substances. […] Once a diagnosis of asthma has been made, an ICS-containing controller treatment should be initiated because of the greater improvement in lung function than when ICS controller treatment is not used. This is an important change in the 2019 GINA guidelines, as it was previously recommended to give newly diagnosed patients a SABA alone. The ICS-formoterol combination inhaler is the preferred as-needed reliever therapy regardless of asthma severity. […] GINA recommends the following asthma-treatment steps: Step 1: This step is advised for patients with mild asthma who have symptoms less than twice per month and no risk of exacerbations.

• #41 The 2019 GINA Guidelines for Asthma Treatment in Adults

  https://www.uspharmacist.com/article/the-2019-gina-guidelines-for-asthma-treatment-in-adults

  The preferred controller regimen is as-needed low-dose ICS-formoterol or daily low-dose ICS plus as-needed SABA. […] The preferred controller treatment is low-dose ICS-formoterol as maintenance and reliever therapy or medium-dose ICS-LABA as maintenance plus as-needed SABA. […] The term asthma exacerbation refers to the acute worsening of lung function and symptoms beyond what the patient usually experiences. The preferred reliever treatment during an exacerbation is low-dose ICS-formoterol that can be increased as needed when symptoms worsen. […] A short OCS course is a treatment option during an exacerbation when the patient fails to respond to an increased dose of reliever and controller after 2 to 3 days, has a history of sudden severe exacerbations, or has rapidly deteriorating lung function.

• #42 Asthma: Updated Diagnosis and Management Recommendations from GINA | AAFP

  https://www.aafp.org/pubs/afp/issues/2020/0615/p762.html

  As-needed SABA therapy alone is not recommended because of severe exacerbations and mortality risks. […] As-needed use of a low-dose ICS/formoterol combination is preferred in adolescents and adults with mild asthma. […] As-needed use of a low-dose ICS and a SABA is preferred in children six to 11 years of age with mild asthma. […] Controller therapy should be shifted to once-daily administration if symptoms are not controlled with as-needed therapy, minimizing the ICS dose when possible. […] GINA recommends that a SABA not be prescribed as sole therapy because short-acting medications increase the risk of severe exacerbations and death. Adding an ICS daily or as needed reduces this risk. GINA also recommends using the lowest dose of ICS tolerated, including reducing the corticosteroid dose after symptoms are controlled.

• #43 How is asthma treated? | Asthma + Lung UK

  https://www.asthmaandlung.org.uk/conditions/asthma/treatments/how

  This can quickly get symptoms under control. […] Remember: taking your preventer medicine every day is the best way to prevent symptoms from building up into an asthma attack. […] Your GP will probably try you on an add-on treatment before increasing the dose in your usual preventer medicine. […] Always talk to your GP or asthma nurse before stopping or reducing any asthma medicines. […] You’re more likely to be able to cut down on the medicine you’re taking if you’ve had no symptoms for at least three months. […] As well as taking your asthma medicines as prescribed there’s a lot of other things you can do to help your asthma, such as breathing exercises, losing weight, and giving up smoking.

• #44 Medicines and treatment – National Asthma Council Australia

  https://www.nationalasthma.org.au/understanding-asthma/treatment-and-medicines

  Some children with asthma need to take regular preventer treatment every day, as well as taking their reliever when they have symptoms. […] Most preschool children do not need preventer treatment. Your child may need preventer treatment if wheezing occurs often and it is hard work to breathe when wheezing (e.g. your childs chest sucks in while breathing in), if wheezing is severe enough to interrupt eating, play, exercise or sleep, or if your child has been hospitalised because of breathing problems. […] Each persons asthma medicines may be adjusted up and down if necessary to achieve the best possible control of symptoms and avoid flare-ups. The aim is to use the lowest doses that control symptoms. […] If your asthma has been very well controlled for at least 3 months, your doctor may suggest that you try decreasing your treatment.

• #45 Asthma Treatment & Management: Approach Considerations, Environmental Control, Allergen Immunotherapy

  https://emedicine.medscape.com/article/296301-treatment

  Omalizumab is indicated for adults and children aged 6 years or older with moderate-to-severe persistent asthma who have a positive skin test result or in vitro reactivity to a perennial aeroallergen and whose symptoms are inadequately controlled with inhaled corticosteroids. […] Bronchial thermoplasty (BT) is a novel intervention for asthma in which controlled thermal energy is delivered to the airway wall during a series of bronchoscopy procedures. […] The mainstay of ED therapy for acute asthma is inhaled beta2 agonists. […] Although use of systemic corticosteroids is recommended early in the course of acute exacerbations in patients with an incomplete response to beta agonists, oral administration is equivalent in efficacy to intravenous administration. […] Optimal management of asthma during pregnancy includes objective monitoring of lung function, avoiding or controlling asthma triggers, patient education, and individualized pharmacologic therapy. Inhaled corticosteroids are the preferred medication for all levels of persistent asthma during pregnancy. […] Aggressive antireflux therapy may improve asthma symptoms and pulmonary function in selected patients. […] Treatment of nasal and sinus inflammation reduces airway reactivity.

• #46 Patient education: Asthma treatment in adolescents and adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/asthma-treatment-in-adolescents-and-adults-beyond-the-basics

  Quick-relief medications, or „relievers,” contain a kind of medicine that rapidly opens the airways to provide relief for asthma symptoms when they happen. […] People with more frequent asthma symptoms or those who are at an increased risk of exacerbations generally need to take medication daily to keep their asthma under control, even if they do not have symptoms every day. The medications prescribed for use every day are called „long-term controller” medications. […] Inhaled steroids (also known as glucocorticoids or corticosteroids) decrease inflammation (eg, swelling) of the airways over time. […] Medications for more severe asthma […] Medications for asthma attacks […] About 8 percent of pregnant women have asthma. With good asthma treatment during pregnancy, nearly all women can have a normal pregnancy and give birth to a healthy baby. It is essential to keep asthma well-controlled during pregnancy to ensure that enough oxygen reaches the growing baby.

• #47 Medicines and treatment – National Asthma Council Australia

  https://www.nationalasthma.org.au/understanding-asthma/treatment-and-medicines

  Some children with asthma need to take regular preventer treatment every day, as well as taking their reliever when they have symptoms. […] Most preschool children do not need preventer treatment. Your child may need preventer treatment if wheezing occurs often and it is hard work to breathe when wheezing (e.g. your childs chest sucks in while breathing in), if wheezing is severe enough to interrupt eating, play, exercise or sleep, or if your child has been hospitalised because of breathing problems. […] Each persons asthma medicines may be adjusted up and down if necessary to achieve the best possible control of symptoms and avoid flare-ups. The aim is to use the lowest doses that control symptoms. […] If your asthma has been very well controlled for at least 3 months, your doctor may suggest that you try decreasing your treatment.

• #48 How Is Asthma Treated?

  https://aafa.org/asthma/asthma-treatment/

  You will probably take more medicine when you begin treatment to get control of your asthma. Work with your doctor to learn which medicine(s) control your asthma best and how much you need. […] Asthma is a chronic condition (which means you will have it all of your life) that is controllable. Unfortunately, there is no cure for asthma. […] Yes, if you have nighttime asthma symptoms. Many people wake up with asthma symptoms such as coughing or wheezing. You can control nighttime symptoms by taking asthma medicines as directed by your doctor. […] Yes. Exercising, particularly in cold air, may cause airway swelling or exercise-induced bronchoconstriction (EIB). Quick-relief asthma medicines, taken before exercise, usually control this. […] Yes. All medicines have side effects. Tell your doctor how you are responding to the treatment and if you have any side effects.

• #49 How Is Asthma Treated?

  https://aafa.org/asthma/asthma-treatment/

  You will probably take more medicine when you begin treatment to get control of your asthma. Work with your doctor to learn which medicine(s) control your asthma best and how much you need. […] Asthma is a chronic condition (which means you will have it all of your life) that is controllable. Unfortunately, there is no cure for asthma. […] Yes, if you have nighttime asthma symptoms. Many people wake up with asthma symptoms such as coughing or wheezing. You can control nighttime symptoms by taking asthma medicines as directed by your doctor. […] Yes. Exercising, particularly in cold air, may cause airway swelling or exercise-induced bronchoconstriction (EIB). Quick-relief asthma medicines, taken before exercise, usually control this. […] Yes. All medicines have side effects. Tell your doctor how you are responding to the treatment and if you have any side effects.

• #50 Asthma Treatment – Treatment Plan | ACAAI Patient

  https://acaai.org/asthma/treatment/

  Often the best way to control asthma symptoms is to avoid whatever causes them. […] Effective treatment of allergic asthma includes identifying and avoiding allergens that trigger symptoms, using drug therapies and developing an emergency action plan for severe attacks. Your allergist may also recommend that you monitor your asthma by using a peak flow meter. […] If you have asthma, it’s important to have a plan in place for a range of situations and symptoms. In fact, one of the single most important steps that you can take to successfully take control and manage your condition is to create an asthma action plan with your allergist. […] There are many effective medicines to treat asthma. Most people with asthma need two kinds: quick-relief medicines and long-term control medicines. […] Although asthma symptoms are controllable, a cure for asthma has remained elusive. Preventive treatment should minimize the difficulties caused by asthma and allow a normal, active lifestyle.

• #51 Asthma – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/asthma/diagnosis-treatment/drc-20369660

  Quick-relief (rescue) medications are used as needed for rapid, short-term symptom relief during an asthma attack. They may also be used before exercise if your doctor recommends it. […] Allergy medications may help if your asthma is triggered or worsened by allergies. […] This treatment is used for severe asthma that doesn’t improve with inhaled corticosteroids or other long-term asthma medications. […] Your treatment should be flexible and based on changes in your symptoms. […] Work with your doctor to create an asthma action plan that outlines in writing when to take certain medications or when to increase or decrease the dose of your medications based on your symptoms. […] Your doctor may also recommend tracking your asthma symptoms or using a peak flow meter on a regular basis to monitor how well your treatment is controlling your asthma.

• #52 How is asthma treated? – National Asthma Council Australia

  https://www.nationalasthma.org.au/understanding-asthma/how-is-asthma-managed

  Some other medicines (e.g. prednisolone tablets) are used for severe asthma flare-ups. Asthma cannot be safely treated without medicines a severe flare-up (attack) could be fatal. […] Using your inhaler properly is important for you to get the full benefit of the medication. […] Everyone with asthma (all children and adults) should have their own, personalised asthma action plan. Asthma action plans should be checked and updated at least once a year. […] Taking reliever medicine often means asthma is not well controlled, and the person may be at risk of serious flare-ups. People who need to take their reliever more than twice a week for asthma symptoms need a check-up. […] If you take regular preventer medicine, never change the dose without talking to your doctor first (unless your written asthma action plan tells you when and how to alter your treatment).

• #53 How is asthma treated? – National Asthma Council Australia

  https://www.nationalasthma.org.au/understanding-asthma/how-is-asthma-managed

  Some other medicines (e.g. prednisolone tablets) are used for severe asthma flare-ups. Asthma cannot be safely treated without medicines a severe flare-up (attack) could be fatal. […] Using your inhaler properly is important for you to get the full benefit of the medication. […] Everyone with asthma (all children and adults) should have their own, personalised asthma action plan. Asthma action plans should be checked and updated at least once a year. […] Taking reliever medicine often means asthma is not well controlled, and the person may be at risk of serious flare-ups. People who need to take their reliever more than twice a week for asthma symptoms need a check-up. […] If you take regular preventer medicine, never change the dose without talking to your doctor first (unless your written asthma action plan tells you when and how to alter your treatment).

• #54 Asthma: Types, Causes, Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/6424-asthma

  The goal of asthma treatment is to control symptoms. Asthma control means you: Can do the things you want to do at work and home. Have no (or minimal) asthma symptoms. Rarely need to use your reliever medicine (rescue inhaler). Sleep without asthma interrupting your rest. […] If your healthcare provider says you have asthma, you’ll need to figure out what triggers an attack. Avoiding the triggers can help you avoid an attack. You can’t prevent yourself from getting asthma, though. […] Asthma can’t be cured, but it can be managed. Children may outgrow asthma as they get older. […] Your healthcare provider can help you manage symptoms, learn your triggers and prevent or manage attacks. […] Talk to your healthcare provider about how to control your symptoms.

• #55 Asthma Medication and Treatment

  https://allergyasthmanetwork.org/what-is-asthma/how-is-asthma-treated/

  If you start to regularly experience symptoms during everyday activities, visit an asthma specialist to discuss whether you need to adjust your treatment plan. […] The Rules of Two, Asthma Control Test (ACT) and The Asthma Impairment and Risk Questionnaire (AirQ) are ways to find out if your asthma is under control. […] Healthcare providers prescribe treatments effective in disease control. They want treatments that are convenient for patients needs and lifestyles. […] Patients want to have a say in their care and treatment choices. We call it Shared Decision-Making. […] If you are unable to afford your asthma medicines, consider these alternatives: […] Most asthma medications are safe for use during pregnancy. […] Yes, babies can develop asthma. […] Over-the-counter asthma medications include inhaled epinephrine, inhaled racepinephrine and ephedrine tablets.

• #56 Asthma Treatments NYC | Mount Sinai – New York

  https://www.mountsinai.org/care/pulmonology/services/asthma/treatments

  Bronchial thermoplasty is another FDA-approved therapy for treating severe asthma. It delivers radiofrequency energy to the airway, smoothing airway muscle that may be causing an asthmatic reaction. […] As part of your individualized asthma treatment plan, you will likely receive a peak flow meter, which provides a portable way for you to assess your lung function on your own. By keeping track of the asthma, you will learn to manage it yourself with guidance from your doctor. With a self-management action plan, you will be prepared to deal with your asthma under all types of conditions.

• #57 How is asthma treated? | Asthma + Lung UK

  https://www.asthmaandlung.org.uk/conditions/asthma/treatments/how

  A long-acting bronchodilator opens up your airways. […] It can lower your risk of asthma attacks. […] Montelukast is a preventer tablet. […] This kind of medicine helps with the inflammation in your airways. […] Your GP may prescribe you oral steroids (usually prednisolone) in addition to your usual asthma medicines. […] Steroids help you get symptoms under control in the short term, or if youve had an asthma attack, by reducing the inflammation in your airways. […] If your symptoms have not improved even though youre taking your preventer medicines, and any add-on medicines as prescribed, you may be referred to a specialist. […] The specialist can do tests to work out if you have severe asthma. […] If you do have an asthma attack, the first line of treatment is your blue reliever inhaler.

• #58 Asthma

  https://www.nhs.uk/conditions/asthma/

  Asthma is a common condition that affects your breathing. It cannot currently be cured, but if it’s well treated you should not have problems with symptoms. […] If you have asthma you’ll be supported by a care team including a GP or nurse, and sometimes a specialist hospital doctor. Your care team will explain how and when to use your medicines, how to monitor your asthma, ways to avoid triggers and reduce your symptoms, and what to do if your symptoms get worse. […] The main treatment for asthma is medicines you breathe in using an inhaler. For most people they work well to reduce or prevent asthma symptoms. […] If inhalers are not enough to stop your symptoms, your care team may also recommend a stronger inhaler or tablets that make breathing easier, such as montelukast. […] If you have a severe asthma attack that does not get better, you may need to be treated in hospital. Hospital treatments may include: oxygen through a mask, using a nebuliser to breathe in high doses of medicine, steroid tablets or injections. […] An asthma attack can be life-threatening. But getting the right asthma treatment reduces the risk.

• #59 Asthma Exacerbation in Adults – Treatment : Emergency Care BC

  https://emergencycarebc.ca/clinical_resource/clinical-summary/asthma-exacerbation-in-adults-treatment/

  Criteria For Safe Discharge Home […] Criteria for discharge must be individualized but in general include: […] Asymptomatic or substantially improved symptoms. […] Peak Expiratory Flow (PEF) >80% or PEF 60-80% and improving. […] Normal oxygen saturation. […] No history of near-death exacerbations. […] Understanding of asthma management, and ability to return if worsening. […] Arrange at discharge: […] Reliever and Controller Medications. […] Inhaler technique, importance of adherence and action plan. […] 50mg Prednisone PO (OR equivalent) daily for at least 5 days. […] Instructions for follow up with primary care at end of 5 days (based on steroid duration). […] Instructions on returning if worsening dyspnea (PEF < 200 L/min or use of inhaler <2h interval), chest pain, confusion or weakness.

• #60 The 2019 GINA Guidelines for Asthma Treatment in Adults

  https://www.uspharmacist.com/article/the-2019-gina-guidelines-for-asthma-treatment-in-adults

  Nonpharmacologic interventions for all asthma patients include breathing exercises, increased physical activity, incorporation of a healthy diet, and avoidance of exposure to smoke and other substances. […] Once a diagnosis of asthma has been made, an ICS-containing controller treatment should be initiated because of the greater improvement in lung function than when ICS controller treatment is not used. This is an important change in the 2019 GINA guidelines, as it was previously recommended to give newly diagnosed patients a SABA alone. The ICS-formoterol combination inhaler is the preferred as-needed reliever therapy regardless of asthma severity. […] GINA recommends the following asthma-treatment steps: Step 1: This step is advised for patients with mild asthma who have symptoms less than twice per month and no risk of exacerbations.

• #61 Asthma Treatment – Treatment Plan | ACAAI Patient

  https://acaai.org/asthma/treatment/

  Often the best way to control asthma symptoms is to avoid whatever causes them. […] Effective treatment of allergic asthma includes identifying and avoiding allergens that trigger symptoms, using drug therapies and developing an emergency action plan for severe attacks. Your allergist may also recommend that you monitor your asthma by using a peak flow meter. […] If you have asthma, it’s important to have a plan in place for a range of situations and symptoms. In fact, one of the single most important steps that you can take to successfully take control and manage your condition is to create an asthma action plan with your allergist. […] There are many effective medicines to treat asthma. Most people with asthma need two kinds: quick-relief medicines and long-term control medicines. […] Although asthma symptoms are controllable, a cure for asthma has remained elusive. Preventive treatment should minimize the difficulties caused by asthma and allow a normal, active lifestyle.

• #62 Difficult-to-Treat and Severe Asthma: Management Strategies | AAFP

  https://www.aafp.org/pubs/afp/issues/2021/0301/p286.html

  Breathing exercises aim to decrease the hyperventilation symptoms of asthma by controlling the patient’s breathing pattern. […] Regular physical exercise should be encouraged for patients with asthma, if tolerated. […] Using a primary care registry to identify patients with asthma who are high risk to ensure they receive prompt, evidence-based care can prevent hospitalizations, improve adherence to guidelines, and decrease overall costs.

• #63 Asthma and complementary therapies | Better Health Channel

  https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/asthma-and-complementary-therapies

  Some people find complementary therapies helpful. But there is not much research to tell us how well they work compared to traditional (mainstream) medicine. […] Do not stop taking your daily asthma preventer medication without talking to your doctor first. […] Many therapies are designed to complement your existing medical treatment not replace it. Keep using your asthma medicines to avoid asthma flare-ups while you try complementary therapies. […] There has been research to investigate the role of acupuncture in the treatment of many conditions. The evidence at this time suggests that acupuncture is not helpful in the treatment of asthma. […] There has not been enough research into herbal medicine to prove it helps asthma. […] Buteyko breathing exercises may reduce asthma symptoms and the use of reliever medicine. There has not been enough research to confirm this.

• #64 Difficult-to-Treat and Severe Asthma: Management Strategies | AAFP

  https://www.aafp.org/pubs/afp/issues/2021/0301/p286.html

  Breathing exercises aim to decrease the hyperventilation symptoms of asthma by controlling the patient’s breathing pattern. […] Regular physical exercise should be encouraged for patients with asthma, if tolerated. […] Using a primary care registry to identify patients with asthma who are high risk to ensure they receive prompt, evidence-based care can prevent hospitalizations, improve adherence to guidelines, and decrease overall costs.

• #65

  https://www.browardcenta.com/throat-conditions/asthma/

  While treatment is an essential part of any Asthma patient’s overall wellness, it is also important to minimize exposure to Asthma triggers as much as possible. […] Lastly, a healthy lifestyle and regular exercise can help you manage your symptoms by preventing excess weight and acid reflux, which may contribute to Asthma symptoms. […] While Asthma can have a significant impact on your quality of life, Asthma Treatment can help alleviate and manage symptoms so that you can live comfortably and fully: […] Effective Asthma Treatment can help prevent and control Asthma attacks by reducing inflammation in the airways for easier breathing and improved airflow. […] By keeping inflammation under control, Asthma Treatment medications and other treatments help prevent airway constriction and mucus buildup that leads to Asthma flare-ups or attacks.

• #66 Asthma and complementary therapies | Better Health Channel

  https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/asthma-and-complementary-therapies

  Yoga may improve asthma symptoms and may reduce medication use but there has not been enough research to confirm this. […] Research has shown it does not improve asthma. […] Hypnosis and meditation do not help with the symptoms of asthma. […] There is no research that shows homeopathy can help people with asthma.

• #67 Asthma and complementary therapies | Better Health Channel

  https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/asthma-and-complementary-therapies

  Some people find complementary therapies helpful. But there is not much research to tell us how well they work compared to traditional (mainstream) medicine. […] Do not stop taking your daily asthma preventer medication without talking to your doctor first. […] Many therapies are designed to complement your existing medical treatment not replace it. Keep using your asthma medicines to avoid asthma flare-ups while you try complementary therapies. […] There has been research to investigate the role of acupuncture in the treatment of many conditions. The evidence at this time suggests that acupuncture is not helpful in the treatment of asthma. […] There has not been enough research into herbal medicine to prove it helps asthma. […] Buteyko breathing exercises may reduce asthma symptoms and the use of reliever medicine. There has not been enough research to confirm this.

• #68 The future of asthma treatment: is a cure possible?

  https://www.labiotech.eu/in-depth/future-asthma-treatment/

  For around 300 million people in the world, whipping out their inhaler a medical device that delivers medicine to the lungs to open up narrowed airways before puffing medicine into their mouth, is a typical response to wheezing, worsened by an asthma attack. […] While inhalers offer momentary relief, it is, however, no cure. But some recent studies have shown therapeutic promise. […] As we observe World Asthma Day on May 2, let us take a look at the recent progress in asthma treatment. […] And although current asthma treatments like inhaled corticosteroids and allergy shots, as well as the latest U.S. Food and Drug Administration (FDA)-approved inhalation aerosol Airsupra provide quick relief from these symptoms, Cliff Han, former biologist and founder of U.S.-based allergy lollipop manufacturing company AllerPops, believes that the microbiota may be the key to a cure.

• #69 The future of asthma treatment: is a cure possible?

  https://www.labiotech.eu/in-depth/future-asthma-treatment/

  This research also looked at how fungi and archaea could influence inflammation in the lungs, illustrating how different microbial compositions are associated with asthma. […] While lifestyle changes could benefit with managing the risk, environmental factors also play a significant role. […] Meanwhile, precision medicine is being heralded as an emerging approach for asthma care, let alone for different disease treatments. […] A study proved that an eNose analysis is accurate, with it being able to differentiate between people diagnosed with the disease and those who arent asthmatic, making it a non-invasive tool for the detection of asthma. […] A high blood eosinophil count of more than 300 cells/L can evaluate the efficacy of drugs like mepolizumab and omalizumab to treat asthma.

• #70 First new asthma attack treatment in 50 years

  https://www.bbc.com/news/articles/cev93777g79o

  Researchers say they have found the first new treatment for asthma attacks in 50 years. […] The injection dampens part of the immune system that can go into overdrive in flare-ups of both asthma and a lung condition called chronic obstructive pulmonary disease (COPD). […] Benralizumab is already used in the most severe cases, but the latest research suggests it could be used routinely for around two million attacks in the UK each year. […] The research team at King’s College London said the drug was a „game-changer” that could „revolutionise” care. […] „Now we can see there are different patterns of inflammation, we can be smarter and get the right treatment, to the right patient, at the right time,” said Prof Mona Bafadhel, from King’s. […] Benralizumab targets a type of white blood cell – called an eosinophil – that can cause inflammation and damage in the lungs.

• #71 The future of asthma treatment: is a cure possible?

  https://www.labiotech.eu/in-depth/future-asthma-treatment/

  Our study on oral microbiota in relation to allergic rhinitis shows close interaction between some bacteria and our immune system. […] That interaction also reduces inflammation against allergens, said Han, who has developed prebiotic lollipops, which is a concoction of supplements that not only ease allergy symptoms but also helps to control asthma in nearly 80% of cases. […] Therefore, modulating the microbiota with the immune system could treat, and more so, cure allergies as well as autoimmune disorders, according to the study. […] The key is to identify which microbiota should be the primary target and how to manage it more efficiently and sustainably. […] Another recent study led by researchers at University of British Columbia in Canada validates Hans research on the relationship between the lung and gut microbiota.

• #72 The future of asthma treatment: is a cure possible?

  https://www.labiotech.eu/in-depth/future-asthma-treatment/

  Another study progressing in asthma therapy research is being conducted by the U.S.-based Arrowhead Pharmaceuticals. […] Reducing expression of the RAGE protein in pulmonary epithelial cells to the degree that ARO-RAGE has demonstrated to date in this study has the potential to treat patients with asthma and other inflammatory lung diseases in a fundamentally new way. […] As pericyte movement is controlled by the protein CXCL12, researchers at Aston University in England, have tested a molecule LIT-927, targeting the expression of the protein. […] Despite this potentially being a long-lasting solution for asthma, more studies are required before the efficacy of the treatment is measured in human beings. […] Although many still rely on corticosteroids which can have adverse effects after long-term use in some people with more research targeting various endotypes of asthma, we might just be close to a cure.

• #73 New discovery could help pave the way for better allergic asthma treatments

  https://keck.usc.edu/news/new-discovery-could-help-pave-the-way-for-better-allergic-asthma-treatments/

  USC researchers working with mouse models and human cells have identified a potential new way to inhibit immune cells that drive the most common form of asthma. […] The findings, which appear in the Journal of Experimental Medicine (JEM), point to a possible new therapeutic approach to reducing lung inflammation and treating allergic asthma most often caused by dust mites, pollen, animal dander and mold spores. […] Given the importance of ILC2s in allergic asthma, there is an urgent need to develop novel mechanism-based approaches to target these critical drivers of inflammation in the lungs. […] In contrast, treatment with a drug called Yoda1 that switches on Piezo1 channels reduced the activity of ILC2s, decreased airway inflammation, and alleviated the symptoms of allergen-exposed mice.

• #74

  https://www.kcl.ac.uk/news/first-new-treatment-asthma-attacks-in-50-years

  First new treatment for asthma attacks in 50 years. An injection given during some asthma and COPD attacks is more effective than the current treatment of steroid tablets, reducing the need for further treatment by 30%. […] Treatment at the point of an exacerbation for this type of asthma has barely changed for over fifty years, with steroid drugs being the mainstay of medication. […] Benralizamab is a monoclonal antibody which targets specific white blood cells, called eosinophils, to reduce lung inflammation. It is currently used for the treatment of severe asthma. […] After ninety days, there were four times fewer people in the benralizumab group that failed treatment compared to standard of care with prednisolone. […] Treatment with the benralizumab injection took longer to fail, meaning fewer episodes to see a doctor or go to hospital. There was also an improvement in the quality of life for people with asthma and COPD.

• #75 First new asthma attack treatment in 50 years

  https://www.bbc.com/news/articles/cev93777g79o

  Eosinophils are implicated in about half of asthma attacks and a third of COPD flare-ups. […] If such an attack – involving difficulty breathing, wheezing, coughing and chest tightness – cannot be controlled with regular inhalers then doctors currently prescribe a course of steroids. […] The results in The Lancet Respiratory Medicine found a treatment failure rate of 74% when taking steroids and 45% with the new therapy. […] People treated with the new therapy were less likely to be admitted to hospital, need another round of treatment or die. […] „This is a game-changer, weve not had a change in treatment for 50 years – it will revolutionise how we treat people when theyre really unwell,” Prof Bafadhel said. […] Volunteers also reported improved symptoms and a better quality of life on the new drug.

• #76 Difficult-to-Treat and Severe Asthma: Management Strategies | AAFP

  https://www.aafp.org/pubs/afp/issues/2021/0301/p286.html

  Bronchial thermoplasty modestly improves quality of life and lowers rates of asthma exacerbation in patients with moderate to severe asthma. […] Difficult-to-treat asthma requires a coordinated holistic approach that addresses the disease and its impact on patients’ lives. Recent advances have expanded the therapeutic options. […] The third step is to optimize management. Patients should be educated on self-assessment of asthma control, understanding asthma medications, proper inhaler technique, and creating a home action plan. Asthma therapy should include a high-dose inhaled corticosteroid plus a long-acting beta agonist (LABA) and rescue therapy. Nonbiologic add-on therapies, such as a long-acting muscarinic agent (LAMA) or leukotriene receptor antagonist, should be considered. […] The clinical response to treatment should be assessed after three to six months. If the asthma is still uncontrolled or therapy cannot be stepped down, the asthma can be reclassified as severe and the patient referred to an allergist or pulmonologist.

• #77 The 2019 GINA Guidelines for Asthma Treatment in Adults

  https://www.uspharmacist.com/article/the-2019-gina-guidelines-for-asthma-treatment-in-adults

  Severe or difficult-to-treat asthma refers to uncontrolled asthma at treatment steps 4 and 5 despite adequate adherence to treatment and treatment of contributory factors. […] If nonbiologics such as LABA, tiotropium, and leukotriene modifiers fail to manage a patient’s asthma symptoms, then biologics may be considered depending on the price and the patient’s resources. […] Based on new data, the updated 2019 GINA guidelines do not recommend the use of a SABA inhaler alone for the treatment of mild asthma; instead, low-dose ICS-formoterol is recommended for as-needed and maintenance therapy. For patients who present with severe or difficult-to-treat asthma, other options may be considered as add-on treatment to inhaler therapy, including LTRA, tiotropium, biologics, azithromycin, and OCS.

• #78

  https://www.browardcenta.com/throat-conditions/asthma/

  With effective Asthma management through treatment, you can engage in normal daily activities and exercise without breathing difficulties. […] Consistent treatment prevents lung remodeling to keep you breathing better longer. […] Effective treatment decreases the need for emergency Asthma care, hospitalizations, and oral steroid use by preventing severe attacks. […] With good long-term inflammation control, some patients are able to decrease their dosages of daily medications.

• #79 The future of asthma treatment: is a cure possible?

  https://www.labiotech.eu/in-depth/future-asthma-treatment/

  Another study progressing in asthma therapy research is being conducted by the U.S.-based Arrowhead Pharmaceuticals. […] Reducing expression of the RAGE protein in pulmonary epithelial cells to the degree that ARO-RAGE has demonstrated to date in this study has the potential to treat patients with asthma and other inflammatory lung diseases in a fundamentally new way. […] As pericyte movement is controlled by the protein CXCL12, researchers at Aston University in England, have tested a molecule LIT-927, targeting the expression of the protein. […] Despite this potentially being a long-lasting solution for asthma, more studies are required before the efficacy of the treatment is measured in human beings. […] Although many still rely on corticosteroids which can have adverse effects after long-term use in some people with more research targeting various endotypes of asthma, we might just be close to a cure.

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