Materiały źródłowe

• #1 Irritable Bowel Syndrome – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK534810/

  Irritable bowel syndrome (IBS) is a prevalent, long-term gastrointestinal disorder that affects the interaction between the gut and brain. This condition is primarily characterized by recurring abdominal pain and irregular bowel movements without an identifiable underlying cause. […] Although the exact cause remains unclear, factors such as gut motility changes, visceral hypersensitivity, and psychological influences might have a role. Potential underlying causes include immune responses following infections, changes in gut permeability due to diet, and shifts in gut microbiota. […] The etiology of IBS is broad and not clearly understood. However, gastrointestinal motility, visceral sensation, brain-gut interaction, and psychosocial distress can all play a role in developing IBS. […] Several theories have been proposed to explain the etiology of IBS. Abnormal transit profiles and a heightened perception of normal motility may be present.

• #2 Irritable bowel syndrome – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/irritable-bowel-syndrome/symptoms-causes/syc-20360016

  Irritable bowel syndrome (IBS) is a common condition that affects the stomach and intestines, also called the gastrointestinal tract. […] The exact cause of IBS isn’t known. Factors that appear to play a role include: […] Muscle contractions in the intestine. The walls of the intestines are lined with layers of muscle that contract as they move food through the digestive tract. Contractions that are stronger and last longer than usual can cause gas, bloating and diarrhea. Weak contractions can slow food passage and lead to hard, dry stools. […] Nervous system. Issues with the nerves in the digestive system may cause discomfort when the belly area, called the abdomen, stretches from gas or stool. Poorly coordinated signals between the brain and the intestines can cause the body to overreact to changes that typically occur in the digestive process. This can result in pain, diarrhea or constipation.

• #3 Irritable Bowel Syndrome (IBS): Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/4342-irritable-bowel-syndrome-ibs

  Irritable bowel syndrome (IBS) is a group of symptoms that affect your digestive system. […] Researchers don’t know exactly what causes IBS, but they classify it as a neurogastrointestinal (GI) disorder. […] Other potential causes of IBS include: Gut bacteria: Research has shown that people with IBS may have altered bacteria in their GI tract, contributing to symptoms. […] Severe infections: Some people get diagnosed with IBS after a severe infection affecting their GI tract, suggesting germs may play a role. […] Food intolerance: Sensitivities or allergies to certain foods may contribute to IBS. […] Childhood stress: IBS is more common in people who experienced severe stressors in childhood, including physical, sexual and emotional abuse.

• #4 Symptoms & Causes of Irritable Bowel Syndrome – NIDDK

  https://www.niddk.nih.gov/health-information/digestive-diseases/irritable-bowel-syndrome/symptoms-causes

  Doctors arent sure what causes IBS. Experts think that a combination of problems may lead to IBS. Different factors may cause IBS in different people. […] Functional gastrointestinal (GI) disorders such as IBS are problems with brain-gut interactionhow your brain and gut work together. Experts think that problems with brain-gut interaction may affect how your body works and cause IBS symptoms. […] Certain problems are more common in people with IBS. Experts think these problems may play a role in causing IBS. These problems include stressful or difficult early life events, such as physical or sexual abuse, certain mental disorders, such as depression, anxiety, and somatic symptom disorder, bacterial infections in your digestive tract, small intestinal bacterial overgrowth, an increase in the number or a change in the type of bacteria in your small intestine, food intolerances or sensitivities, in which certain foods cause digestive symptoms. […] Research suggests that genes may make some people more likely to develop IBS.

• #5 Irritable bowel syndrome (IBS): Symptoms, treatment, and more

  https://www.medicalnewstoday.com/articles/37063

  The gut and brain are connected, meaning a problem with one can affect the other. This is known as the gut-brain axis. Researchers are still learning how it works, but there is evidence that severe stress may affect gut health. […] Gut motility refers to the speed at which the intestines push food through the digestive tract. If motility is too fast or too slow, it may result in IBS symptoms. […] The viscera, or intestines, contain nerves that convey pain signals to the brain. If these nerves become hypersensitive, a person may perceive pain that they otherwise would not. […] Scientists are still trying to understand how IBS develops, but an imbalanced microbiome, antibiotic use, gut infections, and psychological stress may be important risk factors. These things may change how the gut functions, resulting in symptoms.

• #6 Causes and Risk Factors of Irritable Bowel Syndrome (IBS)

  https://www.health.com/what-causes-irritable-bowel-syndrome-8738053

  Irritable bowel syndrome (IBS) is a gastrointestinal (GI) disorder that causes symptoms like abdominal pain and bloating, as well as bowel movement changes like diarrhea, constipation, or both. […] Experts have not identified a definitive cause for IBS, but a combination of factors likely plays a role in its development. […] What causes IBS is not fully understood, but researchers have several theories about the underlying mechanisms that contribute to its development. […] Growing evidence suggests that IBS may develop due to abnormalities in gut microbiota makeup, gut motility, and immune system function. […] The gut-brain axis is a communication network between the digestive tract and the brain. […] Problems with the communication system can lead to heightened sensitivity in the gut, which may explain why people with IBS experience discomfort or pain as food moves through the intestines.

• #7 Irritable bowel syndrome: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000246.htm

  Irritable bowel syndrome (IBS) is a disorder that leads to pain in abdomen and changes in bowel movements. […] The reasons why IBS develops are not clear. It can occur after a bacterial infection or a parasitic infection (giardiasis) of the intestines. This is called postinfectious IBS. There may also be other triggers, including stress. […] The intestine is connected to the brain by hormone and nerve signals that go back and forth between the bowel and the brain. These signals affect bowel function and symptoms. The nerves can become more active during stress. This can cause the intestines to be more sensitive and contract more. […] IBS can occur at any age. Often, it begins in the teen years or early adulthood. It is twice as common in women as in men. […] It is less likely to begin in people above 50 years of age. […] About 10% to 15% of people in the United States have symptoms of IBS. It is the most common intestinal problem that causes people to be referred to a bowel specialist (gastroenterologist).

• #8 Irritable Bowel Syndrome (IBS): Symptoms & Causes | NewYork-Presbyterian

  https://www.nyp.org/digestive/disorders-of-gut-brain-interaction-dgbi/irritable-bowel-syndrome

  What Causes IBS? […] Experts are uncertain about what causes IBS. The cause may differ from person to person. IBS is diagnosed by its symptoms, as there are no apparent abnormalities in the digestive tract. People with IBS may notice that certain foods, medications, or emotional stressors trigger IBS symptoms. Some possible causes of IBS include: […] Problems with how the muscles of the intestines contract and move food through them (dysmotility) […] Nerves lining the intestines are unusually sensitive so that a person with IBS feels pain more intensely (visceral hypersensitivity) […] Problems in communication between the brain and the digestive tract (brain-gut dysfunction) […] Abnormal changes in the microbiome.

• #9 Irritable Bowel Syndrome – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK534810/

  Another theory suggests that local histamine sensitization of afferent neurons leads to earlier depolarization. […] Increased intestinal permeability has been observed, particularly in diarrhea-predominant IBS. […] An association between gut microorganisms and the immune system has been identified, although this relationship is not yet fully understood.

• #10 What Causes IBS? Main Causes and Recognizing Triggers

  https://www.verywellhealth.com/what-causes-ibs-8547849

  Alterations in the gut microbiome can lead to inflammatory and immunologic changes that impair the gastrointestinal (GI) mucosal barrier by increasing gut permeability (the control of compounds passing from inside the GI tract through the gut wall into the rest of the body). […] This, in turn, may interfere with the brain-gut axis, which is the bidirectional communication between the brain and the gut. The brain-gut axis plays an important role in the regulation of gut function. […] Researchers are finding evidence that malfunctions along these nervous system pathways may contribute to symptoms of IBS, such as abdominal pain, diarrhea, and/or constipation. […] Experts suggest that inflammation leads to malfunctions in the nervous system response. This can affect GI motility (the movement of food through the GI tract) and sensitivity and may be involved in functional GI disorders, including IBS.

• #11 Irritable Bowel Syndrome (IBS): Causes, Symptoms, and Treatment

  https://patient.info/digestive-health/irritable-bowel-syndrome-leaflet

  Intolerance to certain foods may play a part in some cases. However, this is thought to be only in a small number of cases. […] Infection and germs (bacteria) in the gut. IBS is not caused by an ongoing gut infection. However, in some cases, the onset of symptoms seems to follow a bout of a gut infection with diarrhoea and being sick (vomiting), called gastroenteritis. So, perhaps a virus or other germ may sensitise or trigger the gut in some way to cause persisting symptoms of IBS. […] Oversensitivity to pain. People with IBS feel more pain when their gut is expanded (dilated) than those without IBS. They may have a lower threshold for experiencing pain from the gut. […] In recent years there has been increasing interest in the links between the gut microbiome, the brain and IBS. The microbiome is the combination of bugs (eg, bacteria and viruses) that are found in the gut. Patients with IBS have a different microbiome pattern to those without IBS. The connections between the gut and the brain are known as the 'gut-brain axis’ and it is this link which has led to the use of psychological therapies sometimes being used to treat IBS.

• #12

  https://fascrs.org/patients/diseases-and-conditions/a-z/irritable-bowel-syndrome-expanded-version

  Irritable bowel syndrome (IBS) is a common disorder affecting over 15 percent of the population. […] While there is no definite cause of this syndrome, the symptoms of IBS seem to occur as a result of abnormal functioning or communication between the nervous system and the muscles of the bowel. […] Environmental factors, genetic factors, bacterial fermentation in the gut, bacterial overgrowth, food intolerance, altered bowel motility, intestinal hypersensitivity, altered nervous system processing, and alterations in hormonal regulation have all been considered as possible causes of IBS. […] Recent studies suggest that IBS symptoms are not all caused by a single mechanism, but are the result of different mechanisms acting on the intestines. […] Irritants may also stimulate nerves in the bowel wall leading to intestinal hypersensitivity and pain.

• #13 Irritable Bowel Syndrome – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK534810/

  Another theory suggests that local histamine sensitization of afferent neurons leads to earlier depolarization. […] Increased intestinal permeability has been observed, particularly in diarrhea-predominant IBS. […] An association between gut microorganisms and the immune system has been identified, although this relationship is not yet fully understood.

• #14 Irritable bowel syndrome – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/irritable-bowel-syndrome/symptoms-causes/syc-20360016

  Irritable bowel syndrome (IBS) is a common condition that affects the stomach and intestines, also called the gastrointestinal tract. […] The exact cause of IBS isn’t known. Factors that appear to play a role include: […] Muscle contractions in the intestine. The walls of the intestines are lined with layers of muscle that contract as they move food through the digestive tract. Contractions that are stronger and last longer than usual can cause gas, bloating and diarrhea. Weak contractions can slow food passage and lead to hard, dry stools. […] Nervous system. Issues with the nerves in the digestive system may cause discomfort when the belly area, called the abdomen, stretches from gas or stool. Poorly coordinated signals between the brain and the intestines can cause the body to overreact to changes that typically occur in the digestive process. This can result in pain, diarrhea or constipation.

• #15 Irritable bowel syndrome – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/irritable-bowel-syndrome/symptoms-causes/syc-20360016

  Irritable bowel syndrome (IBS) is a common condition that affects the stomach and intestines, also called the gastrointestinal tract. […] The exact cause of IBS isn’t known. Factors that appear to play a role include: […] Muscle contractions in the intestine. The walls of the intestines are lined with layers of muscle that contract as they move food through the digestive tract. Contractions that are stronger and last longer than usual can cause gas, bloating and diarrhea. Weak contractions can slow food passage and lead to hard, dry stools. […] Nervous system. Issues with the nerves in the digestive system may cause discomfort when the belly area, called the abdomen, stretches from gas or stool. Poorly coordinated signals between the brain and the intestines can cause the body to overreact to changes that typically occur in the digestive process. This can result in pain, diarrhea or constipation.

• #16

  https://www.parkwayeast.com.sg/conditions-diseases/irritable-bowel-syndrome/symptoms-causes

  Irritable bowel syndrome (IBS) is a chronic disorder that affects the normal functioning of the colon, or large intestine. […] There is still no conclusive evidence on the exact cause for IBS. While there are several well-known theories, the actual science behind IBS remains uncertain. […] Observations of people suffering from the disease provide clues to the probable causes of the condition. […] When stronger, longer-lasting contractions move food through the bowel quickly and forcefully, this leads to gas, bloating, and diarrhoea. […] When weak contractions move food very slowly through the bowel, this leads to constipation. […] Certain bacteria or a virus like gastroenteritis can cause severe diarrhoea and vomiting, which can trigger symptoms of IBS. […] People with IBS may have an increase in the number or change in the type of bacteria in the small intestine leading to symptoms.

• #17 Irritable bowel syndrome – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/irritable-bowel-syndrome/symptoms-causes/syc-20360016

  Irritable bowel syndrome (IBS) is a common condition that affects the stomach and intestines, also called the gastrointestinal tract. […] The exact cause of IBS isn’t known. Factors that appear to play a role include: […] Muscle contractions in the intestine. The walls of the intestines are lined with layers of muscle that contract as they move food through the digestive tract. Contractions that are stronger and last longer than usual can cause gas, bloating and diarrhea. Weak contractions can slow food passage and lead to hard, dry stools. […] Nervous system. Issues with the nerves in the digestive system may cause discomfort when the belly area, called the abdomen, stretches from gas or stool. Poorly coordinated signals between the brain and the intestines can cause the body to overreact to changes that typically occur in the digestive process. This can result in pain, diarrhea or constipation.

• #18

  https://www.parkwayeast.com.sg/conditions-diseases/irritable-bowel-syndrome/symptoms-causes

  Irritable bowel syndrome (IBS) is a chronic disorder that affects the normal functioning of the colon, or large intestine. […] There is still no conclusive evidence on the exact cause for IBS. While there are several well-known theories, the actual science behind IBS remains uncertain. […] Observations of people suffering from the disease provide clues to the probable causes of the condition. […] When stronger, longer-lasting contractions move food through the bowel quickly and forcefully, this leads to gas, bloating, and diarrhoea. […] When weak contractions move food very slowly through the bowel, this leads to constipation. […] Certain bacteria or a virus like gastroenteritis can cause severe diarrhoea and vomiting, which can trigger symptoms of IBS. […] People with IBS may have an increase in the number or change in the type of bacteria in the small intestine leading to symptoms.

• #19 Irritable Bowel Syndrome (IBS) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/irritable-bowel-syndrome-ibs

  Irritable bowel syndrome is a chronic condition that causes abdominal pain and changes in bowel habits, affecting the frequency of bathroom visits and the consistency of stool. […] Doctors arent sure exactly what causes IBS, but there are several factors that make people more likely to develop the condition: […] Optimal digestion depends upon the speed at which food goes through the digestive system. In people with IBS, food may travel more quickly or slowly, resulting in discomfort and altering bowel patterns. […] Some people with IBS have different proportions of gut bacteria than those with healthy digestive systems. […] Foods that make people more prone to gas may aggravate IBS symptoms. […] Some people with IBS have a family history of the condition.

• #20 What Causes IBS? Main Causes and Recognizing Triggers

  https://www.verywellhealth.com/what-causes-ibs-8547849

  IBS has sometimes been called spastic colon due to alterations seen in gut motility in people with IBS. The spasms are spontaneous contractions of the muscles of the intestines. […] Severe bacterial infections in the digestive tract, such as viral or bacterial gastroenteritis, may be a cause for the development of IBS. This is called post-infectious IBS (PI-IBS). […] Experts suggest that PI-IBS may develop in 10% of people with infectious gastroenteritis despite disease resolution. This may be due to persistent low-grade inflammation, changes in intestinal permeability (the ability of a substance to pass through the intestinal lining), increased visceral sensitivity, and alterations in the gut microbiome. […] Antibiotics are known to disrupt the bacteria in the gut. These changes can include reducing species diversity, altering metabolic activity, and increasing the amount of antibiotic-resistant organisms.

• #21 Irritable bowel syndrome – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/irritable-bowel-syndrome/symptoms-causes/syc-20360016

  Severe infection. IBS can develop after a severe bout of diarrhea caused by bacteria or a virus. This is called gastroenteritis. IBS also might be associated with a surplus of bacteria in the intestines, known as bacterial overgrowth. […] Early-life stress. People exposed to stressful events, especially in childhood, tend to have more symptoms of IBS. […] Changes in gut microbes. Examples include changes in bacteria, fungi and viruses, which typically live in the intestines and play a key role in health. Research indicates that the microbes in people with IBS might differ from those in people who don’t have IBS.

• #22 Irritable Bowel Syndrome (IBS): Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/4342-irritable-bowel-syndrome-ibs

  Irritable bowel syndrome (IBS) is a group of symptoms that affect your digestive system. […] Researchers don’t know exactly what causes IBS, but they classify it as a neurogastrointestinal (GI) disorder. […] Other potential causes of IBS include: Gut bacteria: Research has shown that people with IBS may have altered bacteria in their GI tract, contributing to symptoms. […] Severe infections: Some people get diagnosed with IBS after a severe infection affecting their GI tract, suggesting germs may play a role. […] Food intolerance: Sensitivities or allergies to certain foods may contribute to IBS. […] Childhood stress: IBS is more common in people who experienced severe stressors in childhood, including physical, sexual and emotional abuse.

• #23

  https://healthmatch.io/irritable-bowel-syndrome/what-causes-ibs

  A study looking at the microbiome (colonies of bacteria resident naturally in your gut) of people with IBS found a correlation between the severity of IBS symptoms and reduced microbial diversity. […] Unfortunately, no causative link has been found, so its not yet clear if the lack of bacterial diversity causes the IBS symptoms or if the IBS causes the lack of species of good bacteria. […] Approximately one in ten patients can trace their IBS back to an episode of gastroenteritis (infectious diarrhea), and studies show that 3% to 36% of gut infections lead to persistent IBS. […] Infection causes chronic inflammation of the lining of the colon, which then leads to activation of immune cells – also known as leaky gut. […] IBS can cluster in families, and in 2% of cases, there is actually a recognized genetic mutation responsible for IBS.

• #24

  https://healthmatch.io/irritable-bowel-syndrome/what-causes-ibs

  A study looking at the microbiome (colonies of bacteria resident naturally in your gut) of people with IBS found a correlation between the severity of IBS symptoms and reduced microbial diversity. […] Unfortunately, no causative link has been found, so its not yet clear if the lack of bacterial diversity causes the IBS symptoms or if the IBS causes the lack of species of good bacteria. […] Approximately one in ten patients can trace their IBS back to an episode of gastroenteritis (infectious diarrhea), and studies show that 3% to 36% of gut infections lead to persistent IBS. […] Infection causes chronic inflammation of the lining of the colon, which then leads to activation of immune cells – also known as leaky gut. […] IBS can cluster in families, and in 2% of cases, there is actually a recognized genetic mutation responsible for IBS.

• #25 Causes and Risk Factors of Irritable Bowel Syndrome (IBS)

  https://www.health.com/what-causes-irritable-bowel-syndrome-8738053

  Several factors can disrupt the balance of the gut-brain axis, including stress, childhood trauma, anxiety and depression, and visceral hypersensitivity. […] Research shows that many people with IBS have imbalances in their gut microbiota, which may contribute to the development of IBS. […] Dysbiosis may disrupt these interactions, leading to increased gut sensitivity and gut motility problems. […] While IBS is a functional GI disorder, research suggests immune system dysfunction may contribute to its development. […] Many people with IBS have food intolerances or sensitivities that can trigger or worsen their symptoms. […] Genetics may play a role in irritable bowel syndrome, but exactly how remains unclear. […] Research shows that people with a family history of IBS may have a two to three times higher risk of developing the condition themselves.

• #26 What’s causing your IBS – Harvard Health

  https://www.health.harvard.edu/healthbeat/whats-causing-your-ibs

  Irritable bowel syndrome (IBS) can feel like a mystery, but experts have uncovered some clues about what might be causing the discomfort and how to better manage it. […] Though the exact cause isn’t clear, factors like stress, antibiotics, and even bacterial overgrowth are thought to play a role. […] Stress can cause more contractions in the intestines and increase sensitivity. […] However, we do know that people with IBS often have higher levels of stress and anxiety and that this distress also can make IBS symptoms worse. […] When we take antibiotics to combat bacterial infections, the drugs also kill helpful bacteria in the gut. […] Some animal and human research suggests that this disruption may lead to IBS in some cases. […] Some people with IBS also have a surplus of bacteria in the small intestines, a condition called small intestinal bacterial overgrowth (SIBO). […] It’s unclear whether SIBO can be a cause of IBS, but people with IBS are more likely than others to test positive for SIBO. […] In addition, some research has found that IBS symptoms often decrease after antibiotic treatment that focuses on bacteria in the small intestine.

• #27 What Causes IBS? Main Causes and Recognizing Triggers

  https://www.verywellhealth.com/what-causes-ibs-8547849

  Other potential causes include small intestinal bacterial overgrowth (SIBO), increased gut sensitivity, food sensitivities or intolerances, and certain mental health issues. […] Irritable bowel syndrome (IBS) is a multifaceted condition for which the exact cause is unknown. Possible causes include early-life stress or psychological trauma, changes in the gut microbiome, nervous system issues, alterations in gut motility and permeability, severe gastrointestinal infection, and long-term or repeated antibiotic use.

• #28 What Causes IBS? Main Causes and Recognizing Triggers

  https://www.verywellhealth.com/what-causes-ibs-8547849

  Alterations in the gut microbiome can lead to inflammatory and immunologic changes that impair the gastrointestinal (GI) mucosal barrier by increasing gut permeability (the control of compounds passing from inside the GI tract through the gut wall into the rest of the body). […] This, in turn, may interfere with the brain-gut axis, which is the bidirectional communication between the brain and the gut. The brain-gut axis plays an important role in the regulation of gut function. […] Researchers are finding evidence that malfunctions along these nervous system pathways may contribute to symptoms of IBS, such as abdominal pain, diarrhea, and/or constipation. […] Experts suggest that inflammation leads to malfunctions in the nervous system response. This can affect GI motility (the movement of food through the GI tract) and sensitivity and may be involved in functional GI disorders, including IBS.

• #29 Irritable bowel syndrome (IBS): Symptoms, treatment, and more

  https://www.medicalnewstoday.com/articles/37063

  Irritable bowel syndrome (IBS) is a group of digestive symptoms that can cause persistent discomfort. […] Many factors may influence the development IBS, from infections to psychological trauma. […] Scientists are still learning about what leads some people to develop IBS, but there are a few factors that may raise the risk. […] Research suggests a link between IBS and food poisoning and other gut infections. A 2017 study of over 20,000 people found that 10% who experienced an intestinal infection later developed IBS. For those who had protozoa or parasite infections, the rate was 41.9%. […] Dysbiosis is the medical term for an imbalanced gut microbiome. The microbiome is an ecosystem of bacteria and other organisms that live in the intestines, which influence how humans digest and absorb nutrients. Disturbances to this ecosystem, including the use of antibiotics or infections, may play a role in IBS.

• #30 Irritable bowel syndrome – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/irritable-bowel-syndrome/symptoms-causes/syc-20360016

  Severe infection. IBS can develop after a severe bout of diarrhea caused by bacteria or a virus. This is called gastroenteritis. IBS also might be associated with a surplus of bacteria in the intestines, known as bacterial overgrowth. […] Early-life stress. People exposed to stressful events, especially in childhood, tend to have more symptoms of IBS. […] Changes in gut microbes. Examples include changes in bacteria, fungi and viruses, which typically live in the intestines and play a key role in health. Research indicates that the microbes in people with IBS might differ from those in people who don’t have IBS.

• #31 Irritable bowel syndrome – Wikipedia

  https://en.wikipedia.org/wiki/Irritable_bowel_syndrome

  Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by a group of symptoms that commonly include abdominal pain, abdominal bloating, and changes in the consistency of bowel movements. The cause of IBS is not known but multiple factors have been proposed to lead to the condition. Theories include combinations of „gut-brain axis” problems, alterations in gut motility, visceral hypersensitivity, infections including small intestinal bacterial overgrowth, neurotransmitters, genetic factors, and food sensitivity. Onset may be triggered by a stressful life event, or an intestinal infection. […] The risk of developing IBS increases six-fold after having a gastrointestinal infection (gastroenteritis). This is also called post-infectious IBS. The risk of developing IBS following an infection is further increased in those who also had a prolonged fever during the illness. Antibiotic use also appears to increase the risk of developing IBS. Genetic defects in innate immunity and epithelial homeostasis increase the risk of developing both post-infectious as well as other forms of IBS. […] While the causes of IBS are still unknown, it is believed that the entire gut-brain axis is affected.

• #32 The Real Causes of IBS (Irritable Bowel Syndrome) – Nutritionist

  https://www.goodnessme-nutrition.com/ibs/real-causes-ibs/

  Irritable Bowel Syndrome (IBS) is a disorder of the gut-brain connection. Its a condition made up of a collection of digestive symptoms such as bloating, abdominal pain, gas, constipation or diarrhoea. […] Each person with IBS will have a different experience and triggers, partly down to different actual root causes. […] Post infectious IBS is one of the common causes of IBS, thought to cause of 5-32% of IBS. […] These can cause IBS symptoms, and drive ongoing issues after the infection is cleared. […] Slow movement of food through the digestive tract can cause an overgrowth of bacteria, which can increase constipation. […] We can get increased growth of microbes in the small intestine which causes symptoms of IBS. […] The cross over of SIBO in people with IBS is thought to be between 16-70%, so this is worth considering as a cause of your symptoms. […] When these foods arent broken down properly in the small intestine they travel to the large intestine and can cause bloating, gas and cramps. […] The way we think and how we feel can hugely impact on our digestion. […] The causes of IBS are very varied, and may overlap.

• #33 Irritable bowel syndrome – Wikipedia

  https://en.wikipedia.org/wiki/Irritable_bowel_syndrome

  Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by a group of symptoms that commonly include abdominal pain, abdominal bloating, and changes in the consistency of bowel movements. The cause of IBS is not known but multiple factors have been proposed to lead to the condition. Theories include combinations of „gut-brain axis” problems, alterations in gut motility, visceral hypersensitivity, infections including small intestinal bacterial overgrowth, neurotransmitters, genetic factors, and food sensitivity. Onset may be triggered by a stressful life event, or an intestinal infection. […] The risk of developing IBS increases six-fold after having a gastrointestinal infection (gastroenteritis). This is also called post-infectious IBS. The risk of developing IBS following an infection is further increased in those who also had a prolonged fever during the illness. Antibiotic use also appears to increase the risk of developing IBS. Genetic defects in innate immunity and epithelial homeostasis increase the risk of developing both post-infectious as well as other forms of IBS. […] While the causes of IBS are still unknown, it is believed that the entire gut-brain axis is affected.

• #34 What Causes IBS? Main Causes and Recognizing Triggers

  https://www.verywellhealth.com/what-causes-ibs-8547849

  IBS has sometimes been called spastic colon due to alterations seen in gut motility in people with IBS. The spasms are spontaneous contractions of the muscles of the intestines. […] Severe bacterial infections in the digestive tract, such as viral or bacterial gastroenteritis, may be a cause for the development of IBS. This is called post-infectious IBS (PI-IBS). […] Experts suggest that PI-IBS may develop in 10% of people with infectious gastroenteritis despite disease resolution. This may be due to persistent low-grade inflammation, changes in intestinal permeability (the ability of a substance to pass through the intestinal lining), increased visceral sensitivity, and alterations in the gut microbiome. […] Antibiotics are known to disrupt the bacteria in the gut. These changes can include reducing species diversity, altering metabolic activity, and increasing the amount of antibiotic-resistant organisms.

• #35 What Causes IBS? Main Causes and Recognizing Triggers

  https://www.verywellhealth.com/what-causes-ibs-8547849

  IBS has sometimes been called spastic colon due to alterations seen in gut motility in people with IBS. The spasms are spontaneous contractions of the muscles of the intestines. […] Severe bacterial infections in the digestive tract, such as viral or bacterial gastroenteritis, may be a cause for the development of IBS. This is called post-infectious IBS (PI-IBS). […] Experts suggest that PI-IBS may develop in 10% of people with infectious gastroenteritis despite disease resolution. This may be due to persistent low-grade inflammation, changes in intestinal permeability (the ability of a substance to pass through the intestinal lining), increased visceral sensitivity, and alterations in the gut microbiome. […] Antibiotics are known to disrupt the bacteria in the gut. These changes can include reducing species diversity, altering metabolic activity, and increasing the amount of antibiotic-resistant organisms.

• #36 What Causes IBS? Main Causes and Recognizing Triggers

  https://www.verywellhealth.com/what-causes-ibs-8547849

  IBS has sometimes been called spastic colon due to alterations seen in gut motility in people with IBS. The spasms are spontaneous contractions of the muscles of the intestines. […] Severe bacterial infections in the digestive tract, such as viral or bacterial gastroenteritis, may be a cause for the development of IBS. This is called post-infectious IBS (PI-IBS). […] Experts suggest that PI-IBS may develop in 10% of people with infectious gastroenteritis despite disease resolution. This may be due to persistent low-grade inflammation, changes in intestinal permeability (the ability of a substance to pass through the intestinal lining), increased visceral sensitivity, and alterations in the gut microbiome. […] Antibiotics are known to disrupt the bacteria in the gut. These changes can include reducing species diversity, altering metabolic activity, and increasing the amount of antibiotic-resistant organisms.

• #37 What Causes IBS? Main Causes and Recognizing Triggers

  https://www.verywellhealth.com/what-causes-ibs-8547849

  IBS has sometimes been called spastic colon due to alterations seen in gut motility in people with IBS. The spasms are spontaneous contractions of the muscles of the intestines. […] Severe bacterial infections in the digestive tract, such as viral or bacterial gastroenteritis, may be a cause for the development of IBS. This is called post-infectious IBS (PI-IBS). […] Experts suggest that PI-IBS may develop in 10% of people with infectious gastroenteritis despite disease resolution. This may be due to persistent low-grade inflammation, changes in intestinal permeability (the ability of a substance to pass through the intestinal lining), increased visceral sensitivity, and alterations in the gut microbiome. […] Antibiotics are known to disrupt the bacteria in the gut. These changes can include reducing species diversity, altering metabolic activity, and increasing the amount of antibiotic-resistant organisms.

• #38 What Causes I.B.S.? – The New York Times

  https://www.nytimes.com/2021/08/02/well/live/irritable-bowel-syndrome-treatments-causes.html

  And recent research has revealed at least one likely explanation for the symptoms of I.B.S.: an infection in the digestive tract that triggers a localized allergic reaction in the gut. As Dr. Marc E. Rothenberg wrote in The New England Journal of Medicine in June, “Patients with I.B.S. often report that their symptoms started at the time of a gastrointestinal infection.” […] Dr. Rothenberg, who is the director of the division of allergy and immunology at Cincinnati Children’s Hospital Medical Center, explained in an interview that the infection can temporarily disrupt the layer of cells that normally lines the bowel. These cells form a barrier that prevents allergy-inducing proteins in foods from being absorbed. When that barrier is penetrated, people can become intolerant to foods that previously caused them no issue.

• #39 Symptoms & Causes of Irritable Bowel Syndrome – NIDDK

  https://www.niddk.nih.gov/health-information/digestive-diseases/irritable-bowel-syndrome/symptoms-causes

  Doctors arent sure what causes IBS. Experts think that a combination of problems may lead to IBS. Different factors may cause IBS in different people. […] Functional gastrointestinal (GI) disorders such as IBS are problems with brain-gut interactionhow your brain and gut work together. Experts think that problems with brain-gut interaction may affect how your body works and cause IBS symptoms. […] Certain problems are more common in people with IBS. Experts think these problems may play a role in causing IBS. These problems include stressful or difficult early life events, such as physical or sexual abuse, certain mental disorders, such as depression, anxiety, and somatic symptom disorder, bacterial infections in your digestive tract, small intestinal bacterial overgrowth, an increase in the number or a change in the type of bacteria in your small intestine, food intolerances or sensitivities, in which certain foods cause digestive symptoms. […] Research suggests that genes may make some people more likely to develop IBS.

• #40 What causes irritable bowel syndrome IBS?

  https://www.usatoday.com/story/life/health-wellness/2025/02/01/irritable-bowel-syndrome-ibs-causes/77905476007/

  Irritable bowel syndrome, or IBS, is among the most common gastrointestinal conditions today. […] There are several theories about the origins of IBS, Levinthal says, „but no one really knows for sure.” Regardless, one culprit we known can lead to IBS is food sensitivities – especially to foods containing lactose, sorbitol, fructose and other carbohydrates that are poorly absorbed by some people. […] Bacteria in the digestive tract can also cause IBS, as can medications such as antibiotics and painkillers. „Many patients with IBS struggle with disordered mood, have experienced traumatic events early in their lives and/or experience ongoing stress or anxiety,” says Levinthal. „These observations suggest that at least some part of IBS is rooted in the brain.” […] Along with food, gut bacteria, medications and brain-gut signaling, Yale Medicine notes that genetics also likely play a part as some of the people who are diagnosed with the condition have a family history of IBS.

• #41 Causes and Risk Factors of Irritable Bowel Syndrome (IBS)

  https://www.health.com/what-causes-irritable-bowel-syndrome-8738053

  Several factors can disrupt the balance of the gut-brain axis, including stress, childhood trauma, anxiety and depression, and visceral hypersensitivity. […] Research shows that many people with IBS have imbalances in their gut microbiota, which may contribute to the development of IBS. […] Dysbiosis may disrupt these interactions, leading to increased gut sensitivity and gut motility problems. […] While IBS is a functional GI disorder, research suggests immune system dysfunction may contribute to its development. […] Many people with IBS have food intolerances or sensitivities that can trigger or worsen their symptoms. […] Genetics may play a role in irritable bowel syndrome, but exactly how remains unclear. […] Research shows that people with a family history of IBS may have a two to three times higher risk of developing the condition themselves.

• #42 Irritable bowel syndrome – Wikipedia

  https://en.wikipedia.org/wiki/Irritable_bowel_syndrome

  Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by a group of symptoms that commonly include abdominal pain, abdominal bloating, and changes in the consistency of bowel movements. The cause of IBS is not known but multiple factors have been proposed to lead to the condition. Theories include combinations of „gut-brain axis” problems, alterations in gut motility, visceral hypersensitivity, infections including small intestinal bacterial overgrowth, neurotransmitters, genetic factors, and food sensitivity. Onset may be triggered by a stressful life event, or an intestinal infection. […] The risk of developing IBS increases six-fold after having a gastrointestinal infection (gastroenteritis). This is also called post-infectious IBS. The risk of developing IBS following an infection is further increased in those who also had a prolonged fever during the illness. Antibiotic use also appears to increase the risk of developing IBS. Genetic defects in innate immunity and epithelial homeostasis increase the risk of developing both post-infectious as well as other forms of IBS. […] While the causes of IBS are still unknown, it is believed that the entire gut-brain axis is affected.

• #43

  https://healthmatch.io/irritable-bowel-syndrome/what-causes-ibs

  A study looking at the microbiome (colonies of bacteria resident naturally in your gut) of people with IBS found a correlation between the severity of IBS symptoms and reduced microbial diversity. […] Unfortunately, no causative link has been found, so its not yet clear if the lack of bacterial diversity causes the IBS symptoms or if the IBS causes the lack of species of good bacteria. […] Approximately one in ten patients can trace their IBS back to an episode of gastroenteritis (infectious diarrhea), and studies show that 3% to 36% of gut infections lead to persistent IBS. […] Infection causes chronic inflammation of the lining of the colon, which then leads to activation of immune cells – also known as leaky gut. […] IBS can cluster in families, and in 2% of cases, there is actually a recognized genetic mutation responsible for IBS.

• #44 What causes IBS? – The Washington Post

  https://www.washingtonpost.com/wellness/2023/05/15/ibs-causes-irritable-bowel-syndrome/

  Gastroenterologists are also investigating whether covid-19 is linked to IBS. […] Major life stressors go hand-in-hand with IBS-symptom intensity, and people who have experienced traumatic life events have a higher risk of developing IBS. […] Studies have shown that if you have a close relative with IBS, such as a sibling or a parent, then you have an increased chance of having IBS yourself. […] There’s also genetic data supporting the idea that IBS is, in part, sex related: Women tend to be more affected than men. […] Other large studies have revealed that mood disorders share a genetic origin with IBS — and may be why medications that are commonly thought of as anti-depressants or anti-anxiety also help IBS symptoms. […] A recent hypothesis proposed by gastroenterologist Brennan Spiegel at Cedars-Sinai Medical Center in Los Angeles suggests that gravity — or rather, our bodies’ inability to manage it — could be the unifying problem behind IBS. […] But for some people, according to Spiegel, those suspension systems are more susceptible to becoming overstretched. […] There is no single cure for IBS.

• #45 Irritable Bowel Syndrome (IBS) – Gastrointestinal Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/gastrointestinal-disorders/irritable-bowel-syndrome-ibs/irritable-bowel-syndrome-ibs

  Irritable bowel syndrome (IBS previously called functional gastrointestinal [GI] disorders) is a disorder of gut-brain interaction. No anatomic cause can be found on laboratory tests, imaging studies, and biopsies. […] Emotional factors, diet, viral illnesses, or hormones may precipitate or aggravate GI symptoms. […] Although psychosocial factors can be involved, IBS is better understood as a combination of physiologic and psychosocial factors. […] A variety of physiologic factors seem to be involved in IBS symptoms. […] Some patients (perhaps 1 in 7) have reported their IBS symptoms began after an episode of acute gastroenteritis (termed postinfectious IBS). […] However, many patients have no demonstrable physiologic abnormalities, and, even in those who do, the abnormalities may not correlate with symptoms.

• #46 Irritable Bowel Syndrome Cure, Symptoms, Diet, Foods to Avoid

  https://www.medicinenet.com/irritable_bowel_syndrome_ibs/article.htm

  IBS Symptoms The exact cause of irritable bowel syndrome is unknown and may be due to multiple factors. […] The exact cause of irritable bowel syndrome is unknown. It is believed to be due to several factors, including alteration in the gastrointestinal (GI) tract motility, abnormal nervous system signals, increased sensitivity to pain, and food intolerances. […] Gastroenteritis („stomach flu” or „stomach bug”), a viral or bacterial infection of the stomach and intestines, may trigger IBS symptoms. […] Psychological conditions such as anxiety or depression are observed in many people with IBS, though these conditions are not a direct cause of IBS. […] Genetics is thought to be a possible cause of IBS, but so far, this hereditary link has not been proven.

• #47 Irritable bowel syndrome: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000246.htm

  Irritable bowel syndrome (IBS) is a disorder that leads to pain in abdomen and changes in bowel movements. […] The reasons why IBS develops are not clear. It can occur after a bacterial infection or a parasitic infection (giardiasis) of the intestines. This is called postinfectious IBS. There may also be other triggers, including stress. […] The intestine is connected to the brain by hormone and nerve signals that go back and forth between the bowel and the brain. These signals affect bowel function and symptoms. The nerves can become more active during stress. This can cause the intestines to be more sensitive and contract more. […] IBS can occur at any age. Often, it begins in the teen years or early adulthood. It is twice as common in women as in men. […] It is less likely to begin in people above 50 years of age. […] About 10% to 15% of people in the United States have symptoms of IBS. It is the most common intestinal problem that causes people to be referred to a bowel specialist (gastroenterologist).

• #48 5 Common Causes of IBS – Birmingham Gastroenterology Associates

  https://bgapc.com/5-common-causes-of-ibs/

  Severe infections in the body, specifically the digestive tract, can have an effect as well. This is often referred to as post-infectious IBS. […] Stress, along with anxiety and depression, can trigger chemicals in the brain that present pain signals in the gut that can cause your colon to react. However, getting your stress and anxiety under control has been shown to relieve IBS symptoms.

• #49

  https://healthmatch.io/irritable-bowel-syndrome/what-causes-ibs

  Irritable bowel syndrome (IBS) is a common condition, with between 7% and 16% of the US population suffering from symptoms. […] Although IBS was first recognized over 150 years ago, the exact cause for it is still unknown. It seems likely that IBS is multifactorial in origin, with many different factors contributing to the development of the syndrome. […] IBS has been linked to anxiety and depression. People who suffer from IBS have elevated levels of stress hormones in their blood, suggesting that they have an elevated response to stress. […] There is also a well-recognized link between IBS and childhood trauma. However, in 50% of cases, IBS develops primarily in the gut and is followed by psychological symptoms such as anxiety and depression. […] Its most likely that IBS is not a problem with the gut or the brain alone, but rather a dysregulation of the communication between them.

• #50 Irritable bowel syndrome – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/irritable-bowel-syndrome/symptoms-causes/syc-20360016

  Severe infection. IBS can develop after a severe bout of diarrhea caused by bacteria or a virus. This is called gastroenteritis. IBS also might be associated with a surplus of bacteria in the intestines, known as bacterial overgrowth. […] Early-life stress. People exposed to stressful events, especially in childhood, tend to have more symptoms of IBS. […] Changes in gut microbes. Examples include changes in bacteria, fungi and viruses, which typically live in the intestines and play a key role in health. Research indicates that the microbes in people with IBS might differ from those in people who don’t have IBS.

• #51 Irritable Bowel Syndrome (IBS): Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/4342-irritable-bowel-syndrome-ibs

  Irritable bowel syndrome (IBS) is a group of symptoms that affect your digestive system. […] Researchers don’t know exactly what causes IBS, but they classify it as a neurogastrointestinal (GI) disorder. […] Other potential causes of IBS include: Gut bacteria: Research has shown that people with IBS may have altered bacteria in their GI tract, contributing to symptoms. […] Severe infections: Some people get diagnosed with IBS after a severe infection affecting their GI tract, suggesting germs may play a role. […] Food intolerance: Sensitivities or allergies to certain foods may contribute to IBS. […] Childhood stress: IBS is more common in people who experienced severe stressors in childhood, including physical, sexual and emotional abuse.

• #52 What Causes IBS? Main Causes and Recognizing Triggers

  https://www.verywellhealth.com/what-causes-ibs-8547849

  The exact cause of irritable bowel syndrome (IBS) is unknown. Sometimes, it develops after a severe bout of infectious diarrhea or trauma, but most cases have no specific cause. […] Researchers think the causes may lie in how the gut and brain communicate. But there are other possibilities. […] Experts aren’t sure of the exact cause of IBS, but these factors seem to play a role. […] Difficult or stressful early life events, such as physical or sexual abuse, may play a role in causing IBS. Some studies of animals have shown that early life trauma and stress can induce IBS into adulthood. […] Research shows that adverse early life events significantly influence the communication pathways within the brain and the gut. However, the reasons for this are still poorly understood. […] An altered gut microbiome (the mix of microorganisms such as bacteria, viruses, and fungi that live in the gastrointestinal tract) is often seen in people with IBS. This abnormal balance of microbes is often referred to as gut bacterial dysbiosis and is now being investigated as a possible cause of IBS.

• #53

  https://healthmatch.io/irritable-bowel-syndrome/what-causes-ibs

  Irritable bowel syndrome (IBS) is a common condition, with between 7% and 16% of the US population suffering from symptoms. […] Although IBS was first recognized over 150 years ago, the exact cause for it is still unknown. It seems likely that IBS is multifactorial in origin, with many different factors contributing to the development of the syndrome. […] IBS has been linked to anxiety and depression. People who suffer from IBS have elevated levels of stress hormones in their blood, suggesting that they have an elevated response to stress. […] There is also a well-recognized link between IBS and childhood trauma. However, in 50% of cases, IBS develops primarily in the gut and is followed by psychological symptoms such as anxiety and depression. […] Its most likely that IBS is not a problem with the gut or the brain alone, but rather a dysregulation of the communication between them.

• #54 Irritable Bowel Syndrome (IBS): Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/4342-irritable-bowel-syndrome-ibs

  Irritable bowel syndrome (IBS) is a group of symptoms that affect your digestive system. […] Researchers don’t know exactly what causes IBS, but they classify it as a neurogastrointestinal (GI) disorder. […] Other potential causes of IBS include: Gut bacteria: Research has shown that people with IBS may have altered bacteria in their GI tract, contributing to symptoms. […] Severe infections: Some people get diagnosed with IBS after a severe infection affecting their GI tract, suggesting germs may play a role. […] Food intolerance: Sensitivities or allergies to certain foods may contribute to IBS. […] Childhood stress: IBS is more common in people who experienced severe stressors in childhood, including physical, sexual and emotional abuse.

• #55 Causes and Risk Factors of Irritable Bowel Syndrome (IBS)

  https://www.health.com/what-causes-irritable-bowel-syndrome-8738053

  Several factors can disrupt the balance of the gut-brain axis, including stress, childhood trauma, anxiety and depression, and visceral hypersensitivity. […] Research shows that many people with IBS have imbalances in their gut microbiota, which may contribute to the development of IBS. […] Dysbiosis may disrupt these interactions, leading to increased gut sensitivity and gut motility problems. […] While IBS is a functional GI disorder, research suggests immune system dysfunction may contribute to its development. […] Many people with IBS have food intolerances or sensitivities that can trigger or worsen their symptoms. […] Genetics may play a role in irritable bowel syndrome, but exactly how remains unclear. […] Research shows that people with a family history of IBS may have a two to three times higher risk of developing the condition themselves.

• #56 Irritable Bowel Syndrome Causes | Stanford Health Care

  https://stanfordhealthcare.org/medical-conditions/digestion-and-metabolic-health/irritable-bowel-syndrome/causes.html

  What causes irritable bowel syndrome (IBS)? It isn’t clear what causes IBS. The cause may be different for different people. IBS may be caused by problems with the way signals are sent between the brain and the digestive tract. In some people, this miscommunication causes abnormal muscle contractions or spasms, which often cause cramping pain. The spasms may speed the passage of stool, causing diarrhea. Or they may slow it down, causing constipation or bloating. […] People with IBS may have unusually sensitive intestines or problems with the way the muscles of the intestines move. It isn’t known why their intestines are more likely to react strongly to the things that contribute to IBS. […] People who have IBS may start having symptoms because of one or more causes, such as: Eating. (But no particular foods have been linked with IBS.) Stress and psychological issues, such as anxiety and depression. Hormonal changes, such as during the menstrual cycle. Some medicines, such as antibiotics. An infection in the digestive tract, such as salmonella. Genetics. IBS may be more likely to occur in people who have a family history of it.

• #57 Irritable bowel syndrome (IBS) | Better Health Channel

  https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/irritable-bowel-syndrome-ibs

  Food intolerance Foods which are poorly absorbed (such as the the carbohydrates which are referred to as FODMAPS fermentable oligosaccharides, disaccharides, monosaccharides and polyols) are the most common dietary trigger for IBS. […] Emotional stress strong emotions, such as anxiety or stress, can affect the nerves of the bowel in susceptible people. […] Inappropriate regulation of signalling between the brain and the gut. Sometimes this is referred to as visceral hypersensitivity (sensitive gut). […] Medication certain types (such as antibiotics, antacids and painkillers) can lead to constipation or diarrhoea.

• #58 The Real Causes of IBS (Irritable Bowel Syndrome) – Nutritionist

  https://www.goodnessme-nutrition.com/ibs/real-causes-ibs/

  Irritable Bowel Syndrome (IBS) is a disorder of the gut-brain connection. Its a condition made up of a collection of digestive symptoms such as bloating, abdominal pain, gas, constipation or diarrhoea. […] Each person with IBS will have a different experience and triggers, partly down to different actual root causes. […] Post infectious IBS is one of the common causes of IBS, thought to cause of 5-32% of IBS. […] These can cause IBS symptoms, and drive ongoing issues after the infection is cleared. […] Slow movement of food through the digestive tract can cause an overgrowth of bacteria, which can increase constipation. […] We can get increased growth of microbes in the small intestine which causes symptoms of IBS. […] The cross over of SIBO in people with IBS is thought to be between 16-70%, so this is worth considering as a cause of your symptoms. […] When these foods arent broken down properly in the small intestine they travel to the large intestine and can cause bloating, gas and cramps. […] The way we think and how we feel can hugely impact on our digestion. […] The causes of IBS are very varied, and may overlap.

• #59 What Causes I.B.S.? – The New York Times

  https://www.nytimes.com/2021/08/02/well/live/irritable-bowel-syndrome-treatments-causes.html

  The researchers then showed that a similar immune response occurred in 12 patients with I.B.S. when common food allergens like gluten, wheat, soy or milk were injected into the rectum. Every patient with I.B.S. had a localized reaction to one or more of the allergens, but only two of eight people without I.B.S. reacted to any allergen. […] But he added that this and other related research suggests that “common gastrointestinal ailments, such as I.B.S. and functional abdominal pain, may instead be food-induced allergic disorders.” Such findings, the researchers wrote in the January study, hint at “new possibilities for the treatment of irritable bowel syndrome and related abdominal pain disorders,” offering hope that people with I.B.S. may one day find lasting relief.

• #60 Irritable Bowel Syndrome (IBS) – Gastrointestinal Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/gastrointestinal-disorders/irritable-bowel-syndrome-ibs/irritable-bowel-syndrome-ibs

  Constipation may be explained by slower colonic transit, and diarrhea may be explained by faster colonic transit. […] Hormonal fluctuations affect bowel functions in women. […] Psychological distress is common among patients with IBS, especially in those who seek medical care. […] Some patients have anxiety disorders, depression, or a somatization disorder. […] However, stress and emotional conflict do not always coincide with symptom onset and recurrence. […] Psychosocial factors can also affect the outcome in IBS. […] Etiology is unclear but appears to involve both physiologic and psychosocial factors.

• #61 Irritable Bowel Syndrome – Wake Gastroenterology

  https://wakegastro.com/patient-info/patient-education/irritable-bowel-syndrome/

  The colon responds strongly to stimuli (for example, foods or stress) that would not bother most people. […] In people with IBS, stress and emotions can strongly affect the colon. It has many nerves that connect it to the brain. […] Research has shown that very mild or hidden (occult) celiac disease is present in a smaller group of people with symptoms that mimic IBS. […] The following have been associated with a worsening of IBS symptoms: large meals, bloating from gas in the colon, medicines, wheat, rye, barley, chocolate, milk products, or alcohol, drinks with caffeine, such as coffee, tea, or colas, stress, conflict, or emotional upsets. […] Researchers have also found that women with IBS may have more symptoms during their menstrual periods, suggesting that reproductive hormones can exacerbate IBS problems.

• #62 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Causes-of-Irritable-Bowel-Syndrome.aspx

  The actual causes of Irritable bowel Syndrome or IBS is as yet unclear. Some researchers speculate that the disease has roots in the central nervous system while another theory speculates that its associations are with the bodys immune system. […] There is another hypothesis that sufferers of IBS are usually more sensitive to certain food types. They have a damaged immune system that normally aids in fighting infections. […] Some researchers suggest that IBS has a basis in a bacterial infection of the gut. This is often seen as a post-infection or Post-gastroenteritis IBS. […] Stress, anxiety, loss of sleep may aggravate IBS symptoms. Sometimes stress and anxiety may be cause for the condition as well. […] Hormonal changes In women symptoms are usually worse during menstrual periods. This raises speculation that changes in blood levels of female sex hormones may be linked to IBS.

• #63 Irritable bowel syndrome: MedlinePlus Medical EncyclopediaLock

  https://medlineplus.gov/ency/article/000246.htm

  Irritable bowel syndrome (IBS) is a disorder that leads to pain in abdomen and changes in bowel movements. […] The reasons why IBS develops are not clear. It can occur after a bacterial infection or a parasitic infection (giardiasis) of the intestines. This is called postinfectious IBS. There may also be other triggers, including stress. […] The intestine is connected to the brain by hormone and nerve signals that go back and forth between the bowel and the brain. These signals affect bowel function and symptoms. The nerves can become more active during stress. This can cause the intestines to be more sensitive and contract more. […] IBS can occur at any age. Often, it begins in the teen years or early adulthood. It is twice as common in women as in men. […] It is less likely to begin in people above 50 years of age. […] About 10% to 15% of people in the United States have symptoms of IBS. It is the most common intestinal problem that causes people to be referred to a bowel specialist (gastroenterologist).

• #64 What causes IBS? – The Washington Post

  https://www.washingtonpost.com/wellness/2023/05/15/ibs-causes-irritable-bowel-syndrome/

  Gastroenterologists are also investigating whether covid-19 is linked to IBS. […] Major life stressors go hand-in-hand with IBS-symptom intensity, and people who have experienced traumatic life events have a higher risk of developing IBS. […] Studies have shown that if you have a close relative with IBS, such as a sibling or a parent, then you have an increased chance of having IBS yourself. […] There’s also genetic data supporting the idea that IBS is, in part, sex related: Women tend to be more affected than men. […] Other large studies have revealed that mood disorders share a genetic origin with IBS — and may be why medications that are commonly thought of as anti-depressants or anti-anxiety also help IBS symptoms. […] A recent hypothesis proposed by gastroenterologist Brennan Spiegel at Cedars-Sinai Medical Center in Los Angeles suggests that gravity — or rather, our bodies’ inability to manage it — could be the unifying problem behind IBS. […] But for some people, according to Spiegel, those suspension systems are more susceptible to becoming overstretched. […] There is no single cure for IBS.

• #65 What causes IBS? – The Washington Post

  https://www.washingtonpost.com/wellness/2023/05/15/ibs-causes-irritable-bowel-syndrome/

  Gastroenterologists are also investigating whether covid-19 is linked to IBS. […] Major life stressors go hand-in-hand with IBS-symptom intensity, and people who have experienced traumatic life events have a higher risk of developing IBS. […] Studies have shown that if you have a close relative with IBS, such as a sibling or a parent, then you have an increased chance of having IBS yourself. […] There’s also genetic data supporting the idea that IBS is, in part, sex related: Women tend to be more affected than men. […] Other large studies have revealed that mood disorders share a genetic origin with IBS — and may be why medications that are commonly thought of as anti-depressants or anti-anxiety also help IBS symptoms. […] A recent hypothesis proposed by gastroenterologist Brennan Spiegel at Cedars-Sinai Medical Center in Los Angeles suggests that gravity — or rather, our bodies’ inability to manage it — could be the unifying problem behind IBS. […] But for some people, according to Spiegel, those suspension systems are more susceptible to becoming overstretched. […] There is no single cure for IBS.

• #66 Irritable Bowel Syndrome (IBS) Symptoms, Causes, and Treatments

  https://www.webmd.com/ibs/digestive-diseases-irritable-bowel-syndrome

  What Causes IBS? […] While several things are known to trigger IBS symptoms, experts don’t know what causes the condition. […] Studies suggest that the colon gets hypersensitive, overreacting to mild stimulation. Instead of slow, rhythmic muscle movements, the bowel muscles spasm. That can cause diarrhea or constipation. […] Another theory suggests it may involve chemicals made by the body, such as serotonin and gastrin, that control nerve signals between the brain and digestive tract. […] Other researchers are studying to see if certain bacteria in the bowels can lead to the condition.

• #67 Irritable Bowel Syndrome (IBS) | Bladder & Bowel Community

  https://www.bladderandbowel.org/bowel/bowel-problems/irritable-bowel-syndrome/

  There is a strong correlation between emotional stress and Irritable Bowel Syndrome. IBS can occur to anyone at any stage in their life but commonly the condition starts in early adulthood and can come and go depending on what is happening. Emotional stress can sensitise the gut making it more likely to react to its contents. […] Released from specific cells in the gut wall, such as mast cells and enterochromaffin cells, Serotonin is a response to any aspect that can irritate or aggravate the gut. It can also play a large part in making the gut very sensitive and reactive.

• #68 Irritable Bowel Syndrome: Symptoms, Causes, and More

  https://www.healthline.com/health/irritable-bowel-syndrome

  IBS is a group of intestinal symptoms that can include abdominal cramping, diarrhea, constipation, bloating, and gas. The cause of IBS is not clear but may be related to an overly sensitive colon or immune system. […] Although there are many ways to treat IBS, the exact cause of IBS is unknown. Possible causes include an overly sensitive colon or immune system. Postinfectious IBS is caused by a previous bacterial infection in the gastrointestinal tract. The varied possible causes make IBS difficult to prevent. […] The physical processes involved in IBS can also vary but may consist of the following: slowed or spastic movements of the colon, causing painful cramping; abnormal serotonin levels in the colon, affecting motility and bowel movements; a bacterial imbalance in the digestive tract. […] The exact cause of IBS is unknown, but the condition has been linked to certain foods and mood disorders.

• #69 Irritable Bowel Syndrome (IBS): Causes, Treatment, and More

  https://resources.healthgrades.com/right-care/irritable-bowel-syndrome/irritable-bowel-syndrome

  Brain and gut communication: Issues with how the brain and gut work together to coordinate digestion may cause IBS, including: Serotonin is a hormone that helps the brain and gut communicate and function. As suggested by a 2020 review, some people with IBS have excess serotonin levels, which may lead to diarrhea and discomfort. […] However, more research is needed to confirm how and why IBS develops. […] The cause of the condition is unknown, but theories include colon sensitivity and an imbalance of bacteria in the digestive tract.

• #70

  https://www.parkwayeast.com.sg/conditions-diseases/irritable-bowel-syndrome/symptoms-causes

  Some people with IBS appear to have mild inflammation in the intestines. Such inflammation may be caused by multiple factors. More research is needed to understand its role in causing IBS. […] Sensitive nerves in the intestines can cause excessive contraction of the bowel muscles when eating, leading to cramps in the abdomen.

• #71 Causes and Risk Factors of Irritable Bowel Syndrome (IBS)

  https://www.health.com/what-causes-irritable-bowel-syndrome-8738053

  Several factors can disrupt the balance of the gut-brain axis, including stress, childhood trauma, anxiety and depression, and visceral hypersensitivity. […] Research shows that many people with IBS have imbalances in their gut microbiota, which may contribute to the development of IBS. […] Dysbiosis may disrupt these interactions, leading to increased gut sensitivity and gut motility problems. […] While IBS is a functional GI disorder, research suggests immune system dysfunction may contribute to its development. […] Many people with IBS have food intolerances or sensitivities that can trigger or worsen their symptoms. […] Genetics may play a role in irritable bowel syndrome, but exactly how remains unclear. […] Research shows that people with a family history of IBS may have a two to three times higher risk of developing the condition themselves.

• #72 What causes IBS? – The Washington Post

  https://www.washingtonpost.com/wellness/2023/05/15/ibs-causes-irritable-bowel-syndrome/

  Gastroenterologists are also investigating whether covid-19 is linked to IBS. […] Major life stressors go hand-in-hand with IBS-symptom intensity, and people who have experienced traumatic life events have a higher risk of developing IBS. […] Studies have shown that if you have a close relative with IBS, such as a sibling or a parent, then you have an increased chance of having IBS yourself. […] There’s also genetic data supporting the idea that IBS is, in part, sex related: Women tend to be more affected than men. […] Other large studies have revealed that mood disorders share a genetic origin with IBS — and may be why medications that are commonly thought of as anti-depressants or anti-anxiety also help IBS symptoms. […] A recent hypothesis proposed by gastroenterologist Brennan Spiegel at Cedars-Sinai Medical Center in Los Angeles suggests that gravity — or rather, our bodies’ inability to manage it — could be the unifying problem behind IBS. […] But for some people, according to Spiegel, those suspension systems are more susceptible to becoming overstretched. […] There is no single cure for IBS.

• #73 What causes IBS? – The Washington Post

  https://www.washingtonpost.com/wellness/2023/05/15/ibs-causes-irritable-bowel-syndrome/

  Gastroenterologists are also investigating whether covid-19 is linked to IBS. […] Major life stressors go hand-in-hand with IBS-symptom intensity, and people who have experienced traumatic life events have a higher risk of developing IBS. […] Studies have shown that if you have a close relative with IBS, such as a sibling or a parent, then you have an increased chance of having IBS yourself. […] There’s also genetic data supporting the idea that IBS is, in part, sex related: Women tend to be more affected than men. […] Other large studies have revealed that mood disorders share a genetic origin with IBS — and may be why medications that are commonly thought of as anti-depressants or anti-anxiety also help IBS symptoms. […] A recent hypothesis proposed by gastroenterologist Brennan Spiegel at Cedars-Sinai Medical Center in Los Angeles suggests that gravity — or rather, our bodies’ inability to manage it — could be the unifying problem behind IBS. […] But for some people, according to Spiegel, those suspension systems are more susceptible to becoming overstretched. […] There is no single cure for IBS.

• #74 What causes IBS? – The Washington Post

  https://www.washingtonpost.com/wellness/2023/05/15/ibs-causes-irritable-bowel-syndrome/

  Gastroenterologists are also investigating whether covid-19 is linked to IBS. […] Major life stressors go hand-in-hand with IBS-symptom intensity, and people who have experienced traumatic life events have a higher risk of developing IBS. […] Studies have shown that if you have a close relative with IBS, such as a sibling or a parent, then you have an increased chance of having IBS yourself. […] There’s also genetic data supporting the idea that IBS is, in part, sex related: Women tend to be more affected than men. […] Other large studies have revealed that mood disorders share a genetic origin with IBS — and may be why medications that are commonly thought of as anti-depressants or anti-anxiety also help IBS symptoms. […] A recent hypothesis proposed by gastroenterologist Brennan Spiegel at Cedars-Sinai Medical Center in Los Angeles suggests that gravity — or rather, our bodies’ inability to manage it — could be the unifying problem behind IBS. […] But for some people, according to Spiegel, those suspension systems are more susceptible to becoming overstretched. […] There is no single cure for IBS.

• #75 Understanding the Different Causes of Irritable Bowel Syndrome: Samuel I. Fink, MD: Internal Medicine

  https://www.samuelfinkmd.com/blog/understanding-the-different-causes-of-irritable-bowel-syndrome

  The exact cause of irritable bowel syndrome is unknown, but certain things can trigger symptoms. […] Researchers found that a previous infection with a stomach bug can cause changes in the way the immune system responds to certain foods. […] The team of gastroenterologists noted that IBS symptoms commonly start after a digestive infection, such as food poisoning. […] This suggests that a digestive infection may cause sensitization to certain foods present at the time of the infection and trigger changes in the immune system that cause IBS symptoms.

• #76 Understanding the Different Causes of Irritable Bowel Syndrome: Samuel I. Fink, MD: Internal Medicine

  https://www.samuelfinkmd.com/blog/understanding-the-different-causes-of-irritable-bowel-syndrome

  The exact cause of irritable bowel syndrome is unknown, but certain things can trigger symptoms. […] Researchers found that a previous infection with a stomach bug can cause changes in the way the immune system responds to certain foods. […] The team of gastroenterologists noted that IBS symptoms commonly start after a digestive infection, such as food poisoning. […] This suggests that a digestive infection may cause sensitization to certain foods present at the time of the infection and trigger changes in the immune system that cause IBS symptoms.

• #77 Irritable Bowel Syndrome – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK534810/

  Irritable bowel syndrome (IBS) is a prevalent, long-term gastrointestinal disorder that affects the interaction between the gut and brain. This condition is primarily characterized by recurring abdominal pain and irregular bowel movements without an identifiable underlying cause. […] Although the exact cause remains unclear, factors such as gut motility changes, visceral hypersensitivity, and psychological influences might have a role. Potential underlying causes include immune responses following infections, changes in gut permeability due to diet, and shifts in gut microbiota. […] The etiology of IBS is broad and not clearly understood. However, gastrointestinal motility, visceral sensation, brain-gut interaction, and psychosocial distress can all play a role in developing IBS. […] Several theories have been proposed to explain the etiology of IBS. Abnormal transit profiles and a heightened perception of normal motility may be present.

• #78 Irritable bowel syndrome (IBS) | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/stomach-liver-and-gastrointestinal-tract/irritable-bowel-syndrome-ibs/

  Irritable bowel syndrome (IBS) is a common, long-term condition of the digestive system. […] The exact cause of IBS is unknown. Many causes have been suggested but none have been proven to lead to IBS.

• #79 Symptoms & Causes of Irritable Bowel Syndrome – NIDDK

  https://www.niddk.nih.gov/health-information/digestive-diseases/irritable-bowel-syndrome/symptoms-causes

  Doctors arent sure what causes IBS. Experts think that a combination of problems may lead to IBS. Different factors may cause IBS in different people. […] Functional gastrointestinal (GI) disorders such as IBS are problems with brain-gut interactionhow your brain and gut work together. Experts think that problems with brain-gut interaction may affect how your body works and cause IBS symptoms. […] Certain problems are more common in people with IBS. Experts think these problems may play a role in causing IBS. These problems include stressful or difficult early life events, such as physical or sexual abuse, certain mental disorders, such as depression, anxiety, and somatic symptom disorder, bacterial infections in your digestive tract, small intestinal bacterial overgrowth, an increase in the number or a change in the type of bacteria in your small intestine, food intolerances or sensitivities, in which certain foods cause digestive symptoms. […] Research suggests that genes may make some people more likely to develop IBS.

• #80 Causes and Risk Factors of Irritable Bowel Syndrome (IBS)

  https://www.health.com/what-causes-irritable-bowel-syndrome-8738053

  Certain lifestyle and environmental factors can increase your risk of developing IBS, including family history, trauma history, mental health conditions, food intolerances, infections, and lifestyle factors. […] IBS is believed to be a disorder of the gut-brain interaction, or how your gut and brain work together. […] While the exact causes of IBS are not fully understood, factors like gut microbiota imbalances, immune dysfunction, and genetics likely play a role.

• #81 Irritable Bowel Syndrome – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK534810/

  Another theory suggests that local histamine sensitization of afferent neurons leads to earlier depolarization. […] Increased intestinal permeability has been observed, particularly in diarrhea-predominant IBS. […] An association between gut microorganisms and the immune system has been identified, although this relationship is not yet fully understood.

• #82 Irritable Bowel Syndrome (IBS): Symptoms & Causes | NewYork-Presbyterian

  https://www.nyp.org/digestive/disorders-of-gut-brain-interaction-dgbi/irritable-bowel-syndrome

  What Causes IBS? […] Experts are uncertain about what causes IBS. The cause may differ from person to person. IBS is diagnosed by its symptoms, as there are no apparent abnormalities in the digestive tract. People with IBS may notice that certain foods, medications, or emotional stressors trigger IBS symptoms. Some possible causes of IBS include: […] Problems with how the muscles of the intestines contract and move food through them (dysmotility) […] Nerves lining the intestines are unusually sensitive so that a person with IBS feels pain more intensely (visceral hypersensitivity) […] Problems in communication between the brain and the digestive tract (brain-gut dysfunction) […] Abnormal changes in the microbiome.

• #83 Irritable bowel syndrome – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/irritable-bowel-syndrome/symptoms-causes/syc-20360016

  Irritable bowel syndrome (IBS) is a common condition that affects the stomach and intestines, also called the gastrointestinal tract. […] The exact cause of IBS isn’t known. Factors that appear to play a role include: […] Muscle contractions in the intestine. The walls of the intestines are lined with layers of muscle that contract as they move food through the digestive tract. Contractions that are stronger and last longer than usual can cause gas, bloating and diarrhea. Weak contractions can slow food passage and lead to hard, dry stools. […] Nervous system. Issues with the nerves in the digestive system may cause discomfort when the belly area, called the abdomen, stretches from gas or stool. Poorly coordinated signals between the brain and the intestines can cause the body to overreact to changes that typically occur in the digestive process. This can result in pain, diarrhea or constipation.

• #84 IBS Irritable Bowel Syndrome | GI | University of Utah Health

  https://healthcare.utah.edu/gi/conditions/irritable-bowel-syndrome-ibs

  You may get IBS if you have too many bacteria (an overgrowth) or an imbalance of the type of bacteria in your gut. […] You may have IBS if you have altered amounts of body chemicals that communicate nerve signals (neurotransmitters) and GI hormones. […] The way that your gut moves stool through your colon (bowel motility) can cause IBS symptoms. […] If you have IBS, your gut may have problems tolerating certain food. Food sensitivities vary between patients. […] While the link between mental health and IBS is still unknown, experts believe that mental health issues often spark physical symptoms.

• #85 Irritable bowel syndrome – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/irritable-bowel-syndrome/symptoms-causes/syc-20360016

  Severe infection. IBS can develop after a severe bout of diarrhea caused by bacteria or a virus. This is called gastroenteritis. IBS also might be associated with a surplus of bacteria in the intestines, known as bacterial overgrowth. […] Early-life stress. People exposed to stressful events, especially in childhood, tend to have more symptoms of IBS. […] Changes in gut microbes. Examples include changes in bacteria, fungi and viruses, which typically live in the intestines and play a key role in health. Research indicates that the microbes in people with IBS might differ from those in people who don’t have IBS.

• #86 Causes and Risk Factors of Irritable Bowel Syndrome (IBS)

  https://www.health.com/what-causes-irritable-bowel-syndrome-8738053

  Several factors can disrupt the balance of the gut-brain axis, including stress, childhood trauma, anxiety and depression, and visceral hypersensitivity. […] Research shows that many people with IBS have imbalances in their gut microbiota, which may contribute to the development of IBS. […] Dysbiosis may disrupt these interactions, leading to increased gut sensitivity and gut motility problems. […] While IBS is a functional GI disorder, research suggests immune system dysfunction may contribute to its development. […] Many people with IBS have food intolerances or sensitivities that can trigger or worsen their symptoms. […] Genetics may play a role in irritable bowel syndrome, but exactly how remains unclear. […] Research shows that people with a family history of IBS may have a two to three times higher risk of developing the condition themselves.

• #87 Irritable bowel syndrome – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/irritable-bowel-syndrome/symptoms-causes/syc-20360016

  Severe infection. IBS can develop after a severe bout of diarrhea caused by bacteria or a virus. This is called gastroenteritis. IBS also might be associated with a surplus of bacteria in the intestines, known as bacterial overgrowth. […] Early-life stress. People exposed to stressful events, especially in childhood, tend to have more symptoms of IBS. […] Changes in gut microbes. Examples include changes in bacteria, fungi and viruses, which typically live in the intestines and play a key role in health. Research indicates that the microbes in people with IBS might differ from those in people who don’t have IBS.

• #88 What Causes IBS? Main Causes and Recognizing Triggers

  https://www.verywellhealth.com/what-causes-ibs-8547849

  IBS has sometimes been called spastic colon due to alterations seen in gut motility in people with IBS. The spasms are spontaneous contractions of the muscles of the intestines. […] Severe bacterial infections in the digestive tract, such as viral or bacterial gastroenteritis, may be a cause for the development of IBS. This is called post-infectious IBS (PI-IBS). […] Experts suggest that PI-IBS may develop in 10% of people with infectious gastroenteritis despite disease resolution. This may be due to persistent low-grade inflammation, changes in intestinal permeability (the ability of a substance to pass through the intestinal lining), increased visceral sensitivity, and alterations in the gut microbiome. […] Antibiotics are known to disrupt the bacteria in the gut. These changes can include reducing species diversity, altering metabolic activity, and increasing the amount of antibiotic-resistant organisms.

• #89 Symptoms & Causes of Irritable Bowel Syndrome – NIDDK

  https://www.niddk.nih.gov/health-information/digestive-diseases/irritable-bowel-syndrome/symptoms-causes

  Doctors arent sure what causes IBS. Experts think that a combination of problems may lead to IBS. Different factors may cause IBS in different people. […] Functional gastrointestinal (GI) disorders such as IBS are problems with brain-gut interactionhow your brain and gut work together. Experts think that problems with brain-gut interaction may affect how your body works and cause IBS symptoms. […] Certain problems are more common in people with IBS. Experts think these problems may play a role in causing IBS. These problems include stressful or difficult early life events, such as physical or sexual abuse, certain mental disorders, such as depression, anxiety, and somatic symptom disorder, bacterial infections in your digestive tract, small intestinal bacterial overgrowth, an increase in the number or a change in the type of bacteria in your small intestine, food intolerances or sensitivities, in which certain foods cause digestive symptoms. […] Research suggests that genes may make some people more likely to develop IBS.

• #90 IBS Irritable Bowel Syndrome | GI | University of Utah Health

  https://healthcare.utah.edu/gi/conditions/irritable-bowel-syndrome-ibs

  Irritable bowel syndrome (IBS) happens when your GI tract (small and large intestine) experiences a group of symptoms. […] Experts think that a combination of problems may cause IBS symptoms. However, experts still dont understand the links between these causes and symptoms. […] IBS symptoms may occur because your nerves struggle to communicate messages between your brain and gut. […] Genes or biological family history may link to IBS. You may be at higher risk of IBS if one or more of your family members have the illness. […] Patients with IBS may be more sensitive to normal movements in the gut. Experts call this type of pain visceral hypersensitivity. […] Bacterial, viral, and parasitic GI tract infections sometimes cause IBS. These infections do not cause IBS in everyone. Researchers dont yet know why infections cause IBS for some people and not others.

• #91 Irritable Bowel Syndrome (IBS) – Gastrointestinal Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/gastrointestinal-disorders/irritable-bowel-syndrome-ibs/irritable-bowel-syndrome-ibs

  Irritable bowel syndrome (IBS previously called functional gastrointestinal [GI] disorders) is a disorder of gut-brain interaction. No anatomic cause can be found on laboratory tests, imaging studies, and biopsies. […] Emotional factors, diet, viral illnesses, or hormones may precipitate or aggravate GI symptoms. […] Although psychosocial factors can be involved, IBS is better understood as a combination of physiologic and psychosocial factors. […] A variety of physiologic factors seem to be involved in IBS symptoms. […] Some patients (perhaps 1 in 7) have reported their IBS symptoms began after an episode of acute gastroenteritis (termed postinfectious IBS). […] However, many patients have no demonstrable physiologic abnormalities, and, even in those who do, the abnormalities may not correlate with symptoms.

• #92

  https://healthmatch.io/irritable-bowel-syndrome/what-causes-ibs

  Irritable bowel syndrome (IBS) is a common condition, with between 7% and 16% of the US population suffering from symptoms. […] Although IBS was first recognized over 150 years ago, the exact cause for it is still unknown. It seems likely that IBS is multifactorial in origin, with many different factors contributing to the development of the syndrome. […] IBS has been linked to anxiety and depression. People who suffer from IBS have elevated levels of stress hormones in their blood, suggesting that they have an elevated response to stress. […] There is also a well-recognized link between IBS and childhood trauma. However, in 50% of cases, IBS develops primarily in the gut and is followed by psychological symptoms such as anxiety and depression. […] Its most likely that IBS is not a problem with the gut or the brain alone, but rather a dysregulation of the communication between them.

• #93 Irritable Bowel Syndrome (IBS): Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/4342-irritable-bowel-syndrome-ibs

  Irritable bowel syndrome (IBS) is a group of symptoms that affect your digestive system. […] Researchers don’t know exactly what causes IBS, but they classify it as a neurogastrointestinal (GI) disorder. […] Other potential causes of IBS include: Gut bacteria: Research has shown that people with IBS may have altered bacteria in their GI tract, contributing to symptoms. […] Severe infections: Some people get diagnosed with IBS after a severe infection affecting their GI tract, suggesting germs may play a role. […] Food intolerance: Sensitivities or allergies to certain foods may contribute to IBS. […] Childhood stress: IBS is more common in people who experienced severe stressors in childhood, including physical, sexual and emotional abuse.

• #94 The Real Causes of IBS (Irritable Bowel Syndrome) – Nutritionist

  https://www.goodnessme-nutrition.com/ibs/real-causes-ibs/

  Irritable Bowel Syndrome (IBS) is a disorder of the gut-brain connection. Its a condition made up of a collection of digestive symptoms such as bloating, abdominal pain, gas, constipation or diarrhoea. […] Each person with IBS will have a different experience and triggers, partly down to different actual root causes. […] Post infectious IBS is one of the common causes of IBS, thought to cause of 5-32% of IBS. […] These can cause IBS symptoms, and drive ongoing issues after the infection is cleared. […] Slow movement of food through the digestive tract can cause an overgrowth of bacteria, which can increase constipation. […] We can get increased growth of microbes in the small intestine which causes symptoms of IBS. […] The cross over of SIBO in people with IBS is thought to be between 16-70%, so this is worth considering as a cause of your symptoms. […] When these foods arent broken down properly in the small intestine they travel to the large intestine and can cause bloating, gas and cramps. […] The way we think and how we feel can hugely impact on our digestion. […] The causes of IBS are very varied, and may overlap.

• #95 Irritable Bowel Syndrome (IBS) – Gastrointestinal Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/gastrointestinal-disorders/irritable-bowel-syndrome-ibs/irritable-bowel-syndrome-ibs

  Constipation may be explained by slower colonic transit, and diarrhea may be explained by faster colonic transit. […] Hormonal fluctuations affect bowel functions in women. […] Psychological distress is common among patients with IBS, especially in those who seek medical care. […] Some patients have anxiety disorders, depression, or a somatization disorder. […] However, stress and emotional conflict do not always coincide with symptom onset and recurrence. […] Psychosocial factors can also affect the outcome in IBS. […] Etiology is unclear but appears to involve both physiologic and psychosocial factors.

• #96 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Causes-of-Irritable-Bowel-Syndrome.aspx

  The actual causes of Irritable bowel Syndrome or IBS is as yet unclear. Some researchers speculate that the disease has roots in the central nervous system while another theory speculates that its associations are with the bodys immune system. […] There is another hypothesis that sufferers of IBS are usually more sensitive to certain food types. They have a damaged immune system that normally aids in fighting infections. […] Some researchers suggest that IBS has a basis in a bacterial infection of the gut. This is often seen as a post-infection or Post-gastroenteritis IBS. […] Stress, anxiety, loss of sleep may aggravate IBS symptoms. Sometimes stress and anxiety may be cause for the condition as well. […] Hormonal changes In women symptoms are usually worse during menstrual periods. This raises speculation that changes in blood levels of female sex hormones may be linked to IBS.

• #97 Irritable Bowel Syndrome (IBS) Symptoms, Causes, and Treatments

  https://www.webmd.com/ibs/digestive-diseases-irritable-bowel-syndrome

  What Causes IBS? […] While several things are known to trigger IBS symptoms, experts don’t know what causes the condition. […] Studies suggest that the colon gets hypersensitive, overreacting to mild stimulation. Instead of slow, rhythmic muscle movements, the bowel muscles spasm. That can cause diarrhea or constipation. […] Another theory suggests it may involve chemicals made by the body, such as serotonin and gastrin, that control nerve signals between the brain and digestive tract. […] Other researchers are studying to see if certain bacteria in the bowels can lead to the condition.

• #98 Irritable Bowel Syndrome: Symptoms, Causes, and More

  https://www.healthline.com/health/irritable-bowel-syndrome

  IBS is a group of intestinal symptoms that can include abdominal cramping, diarrhea, constipation, bloating, and gas. The cause of IBS is not clear but may be related to an overly sensitive colon or immune system. […] Although there are many ways to treat IBS, the exact cause of IBS is unknown. Possible causes include an overly sensitive colon or immune system. Postinfectious IBS is caused by a previous bacterial infection in the gastrointestinal tract. The varied possible causes make IBS difficult to prevent. […] The physical processes involved in IBS can also vary but may consist of the following: slowed or spastic movements of the colon, causing painful cramping; abnormal serotonin levels in the colon, affecting motility and bowel movements; a bacterial imbalance in the digestive tract. […] The exact cause of IBS is unknown, but the condition has been linked to certain foods and mood disorders.

• #99 Irritable Bowel Syndrome (IBS) | Cedars-Sinai

  https://www.cedars-sinai.org/health-library/diseases-and-conditions/i/irritable-bowel-syndrome-ibs.html

  Irritable bowel syndrome (IBS) is a disorder that affects your lower GI (gastrointestinal) tract. […] Health experts have not been able to find an exact physical cause for IBS. It is often thought that stress is one cause. Stress may make IBS symptoms worse. […] The exact cause of IBS isn’t known. There are many possible causes of IBS, and they differ from person to person. This means that some people can have the same symptoms but different causes of their IBS. […] Some things can make IBS symptoms worse. The two things most likely to make your IBS symptoms worse are the foods you eat and having emotional stress. […] The things most likely to make symptoms of IBS worse are diet and emotional stress. […] The exact cause of IBS is not known. There are probably many different causes in different people.

• #100 Causes of IBS – About IBS

  https://aboutibs.org/what-is-ibs/what-causes-ibs/

  The cause of IBS is not completely understood. In IBS, the digestive system appears normal on routine tests. For this reason, it has been referred to as a functional gastrointestinal (GI) disorder. However, there is increasing evidence that the GI symptoms experienced in IBS may be caused by one of more of the following: […] Some of these factors may be more relevant in one individual with IBS, while other factors may be more important in another. […] More needs to be learned about the possible role of bacteria in IBS.

• #101

  https://fascrs.org/patients/diseases-and-conditions/a-z/irritable-bowel-syndrome-expanded-version

  Irritable bowel syndrome (IBS) is a common disorder affecting over 15 percent of the population. […] While there is no definite cause of this syndrome, the symptoms of IBS seem to occur as a result of abnormal functioning or communication between the nervous system and the muscles of the bowel. […] Environmental factors, genetic factors, bacterial fermentation in the gut, bacterial overgrowth, food intolerance, altered bowel motility, intestinal hypersensitivity, altered nervous system processing, and alterations in hormonal regulation have all been considered as possible causes of IBS. […] Recent studies suggest that IBS symptoms are not all caused by a single mechanism, but are the result of different mechanisms acting on the intestines. […] Irritants may also stimulate nerves in the bowel wall leading to intestinal hypersensitivity and pain.

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