Materiały źródłowe

• #1 Polymorphous light eruptions – Indian Journal of Skin Allergy

  https://skinallergyjournal.com/polymorphous-light-eruptions/

  Polymorphous light eruption (PMLE) is the most common, immunologically acquired photo-dermatosis due to delayed hypersensitivity reaction to sunlight. This review article focuses on immunopathogenesis, clinical features, and treatment options involved in PMLE. […] Management of PMLE includes photoprotective measures, systemic photoprotection, photo-hardening, and topical and oral corticosteroids. Photoprotective measures are fundamental in managing PLE. It includes the use of protective clothing, hats, and frequent application of sunscreens. Broad-spectrum sunscreens with a high sun protection factor against both UVA and UVB, along with physical sunscreens (zinc oxide and titanium oxide) are effective in preventing PLE eruptions. […] Photoprotective clothing plays an important role in the prevention of PMLE. UPF (UV protection factor) is used as an indicator for UV protective clothing. Patients are instructed to use full hand sleeves, shoes, sunglasses, scarves, and hats with a wider brim to protect the head, ears, neck, sides of the face, other sun-exposed parts, and to avoid tight-fitting clothes.

• #2

  https://journals.lww.com/idoj/fulltext/2021/12020/polymorphous_light_eruption__an_indian_scenario.1.aspx

  Polymorphous light eruption (PMLE) is the most common, idiopathic, acquired photodermatosis, characterized by abnormal, recurrent, and delayed reaction to sunlight. […] The management of PMLE includes both preventive measures and medical management. […] Sun avoidance is the only definitive way of preventing PMLE. […] Sun protection may be a useful alternative. Sun protection should be advised as a preventive measure during summer months with sun avoidance between 11.00 am and 3.00 pm accompanied by regular application of sunscreens. […] Broad-spectrum sunscreens of the new generation have high SPF and they also provide protection against longer wavelength UVA. Hence, their regular use will provide partial or complete protection against PMLE in almost 90% of patients. […] Patient education regarding proper application technique, quantity to be used, and the necessity to cover all sun-exposed sites including temples, ears, lateral and posterior neck.

• #3 Polymorphous Light Eruption: A Review

  https://scholarlycommons.henryford.com/dermatology_articles/367/

  PMLE is known to be the most common photodermatosis seen in individuals with light skin types; however, recent evidence shows that it is also commonly observed in individuals with skin of color. […] Photohardening, done at the onset of sunny season for patients living in temperate climate, is a commonly used and effective management. […] Management includes photoprotection and photohardening. […] A 710-day course of oral corticosteroids is an appropriate prophylaxis for patients who plan to go to sunny locale for vacation.

• #4 Polymorphic light eruption

  https://www.nhs.uk/conditions/polymorphic-light-eruption/

  Polymorphic light eruption is thought to be caused by UV light altering a substance in the skin, which the immune system reacts to, resulting in the skin becoming inflamed. […] There’s no cure for polymorphic light eruption, but using sunscreens and careful avoidance of the sun will help you manage the rash. […] Avoid the sun, particularly between 11am and 3pm when the sun’s rays are at their strongest, and wear protective clothing when outdoors (unless your doctor has advised you to try hardening your skin). […] Introduce your skin to sunlight gradually in the spring. […] You may be prescribed sunscreens to help prevent the rash developing. […] Use a sunscreen that is SPF 50 or above with a UVA rating of 4 or 5 stars. Apply sunscreen thickly and evenly around 15 to 30 minutes before going out into the sun.

• #5 Interventions for polymorphic light eruption

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6485352/

  To assess the effects of interventions in the prophylaxis and treatment of polymorphic light eruption. […] Preventive management is routinely advocated by sun avoidance between 11 a.m. and 3 p.m., use of protective clothing, and application of sunscreen. […] However, for more severe PLE sufferers, this is rarely adequate. […] The most common are: […] Topical steroids are widely used for mild episodes of PLE. […] An immediate short course of oral prednisolone considerably reduces the severity of itch and rash in people who suffer from occasional, severe attacks of PLE on vacation. […] PsoralenUVA (PUVA), narrowband (NBUVB) or broadband UVB (BBUVB) phototherapy is currently the mainstay of treatment for more severe PLE. […] A course may also be administered in early spring as a preventive treatment to induce skin tolerance for more severe PLE.

• #6

  https://journals.lww.com/idoj/fulltext/2021/12020/polymorphous_light_eruption__an_indian_scenario.1.aspx

  Polymorphous light eruption (PMLE) is the most common, idiopathic, acquired photodermatosis, characterized by abnormal, recurrent, and delayed reaction to sunlight. […] The management of PMLE includes both preventive measures and medical management. […] Sun avoidance is the only definitive way of preventing PMLE. […] Sun protection may be a useful alternative. Sun protection should be advised as a preventive measure during summer months with sun avoidance between 11.00 am and 3.00 pm accompanied by regular application of sunscreens. […] Broad-spectrum sunscreens of the new generation have high SPF and they also provide protection against longer wavelength UVA. Hence, their regular use will provide partial or complete protection against PMLE in almost 90% of patients. […] Patient education regarding proper application technique, quantity to be used, and the necessity to cover all sun-exposed sites including temples, ears, lateral and posterior neck.

• #7 Polymorphous light eruption Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/diseases-conditions/polymorphous-light-eruption

  Polymorphous light eruption (PMLE) is a common skin reaction in people who are sensitive to sunlight (ultraviolet light). […] Protecting your skin from the sun can help prevent PMLE symptoms: Avoid sun exposure during hours of peak sun ray intensity. Use sunscreen. Sun protection with broad spectrum sunblock that works against UVA rays is important. Apply generous amounts of sunscreen with a sun protection factor (SPF) of at least 30. Pay special attention to your face, nose, ears, and shoulders. Apply sunscreen 30 minutes before sun exposure so that it has time to penetrate the skin. Re-apply after swimming and every 2 hours while you are outdoors. Wear a sun hat. Wear sunglasses with UV protection. Use a lip balm with sunscreen.

• #8 Polymorphous light eruption – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/polymorphous-light-eruption/diagnosis-treatment/drc-20355872

  Treatment of polymorphous light eruption often isn’t needed because the rash usually goes away on its own within 10 days. If your symptoms are severe, your healthcare professional may prescribe anti-itch medicine (a corticosteroid cream or pill). […] Your healthcare professional may suggest phototherapy to prevent seasonal episodes of polymorphous light eruption if you have disabling symptoms. This exposes the skin to small doses of UVA or UVB light that helps your skin be less sensitive to light. It mimics the increased exposure you would experience during a summer. […] To lessen the likelihood of recurring episodes of polymorphous light eruption, take the following precautions: […] Avoid the sun between 10 a.m. and 2 p.m. Because the sun’s rays are most intense during this time, try to schedule outdoor activities for other times of the day.

• #9 Polymorphic light eruption (PLE) – British Skin Foundation

  https://knowyourskin.britishskinfoundation.org.uk/condition/polymorphic-light-eruption/

  PLE can come up even when the light has passed through window glass and sometimes even after exposure to fluorescent lighting. […] Most people with PLE get a rash in the spring after they become exposed to strong sunlight for the first time of the year or when visiting countries with a sunny climate, and sometimes it clears up before they return home. […] If the affected area is exposed to more sun the rash will get worse and spread; but as the summer continues, the skin becomes resistant to sunlight and many people can stay longer in the sun. […] The aim of the treatment is both to minimize the severity of the symptoms and prevent the disease from occurring. […] Many people do not have a recurrence if they avoid exposure to the sun and use an effective sunscreen. […] Gradual exposure to sunlight in the springtime may help to reduce the severity of the rash when the summer comes in individuals who have a mild PLE.

• #10 Polymorphous Light Eruption Treatment & Management: Medical Care, Prevention

  https://emedicine.medscape.com/article/1119686-treatment

  Photoavoidance (eg, avoiding sunlight, wearing protective clothing, using sunscreen) remains a key factor in the care of patients with polymorphous (polymorphic) light eruption (PMLE). […] The importance of avoiding sunlight during the hours of most intense UV irradiation (from 10:00 AM to 2:00 PM) and wearing protective clothing (eg, hats, gloves, long pants, long sleeves) should be emphasized to PMLE patients. Wide-spectrum sunscreens with a high SPF and UVA protection should be applied and reapplied during the day. The inclusion of both ecamsule and avobenzone in one sunscreen preparation has been shown to be clinically beneficial for PMLE patients as compared with sunscreen preparations containing either ecamsule or avobenzone alone; each agent filters UVA individually.

• #11 Sun Allergy: Symptoms, Causes, Treatment & Prevention

  https://my.clevelandclinic.org/health/diseases/17681-sun-allergy

  Polymorphous light eruption (PMLE) is more common in females, people with lighter skin, teenagers and young adults. It often appears as small bumps, patches or blisters a few hours after your skin has been exposed to sun. […] Because scientists dont fully understand what causes sun allergies, there arent any strategies to prevent the condition. […] If you have a sun allergy, use the following strategies to prevent episodes: At the start of spring and summer, gradually increase the amount of time you spend in the sun. Thisll help your skin adapt. Avoid the sun when its strongest, from 10 am to 4 pm. Stay indoors or in the shade. Stop using any medications and products that cause photosensitivity. Use protective items, including wide-brimmed hats, long sleeves, pants and window films to block the suns rays. Wear sunscreen with at least 30 SPF. Reapply every two hours or more often if youre sweating or swimming. […] Talk to your healthcare provider about ways to prevent future episodes.

• #12 Polymorphous light eruption – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/polymorphous-light-eruption/diagnosis-treatment/drc-20355872

  Use sunscreen. Fifteen minutes before going outdoors, apply a broad-spectrum sunscreen, one that provides protection from both UVA and UVB light. Use a sunscreen with a sun protection factor (SPF) of at least 30. Apply sunscreen generously, and reapply every two hours or more often if you’re swimming or perspiring. If you’re using a spray sunscreen, be sure to cover the entire area completely. […] Cover up. For protection from the sun, wear tightly woven clothing that covers your arms and legs. Consider wearing a broad-brimmed hat, which provides more protection than does a cap or visor. Consider wearing clothing designed to provide sun protection. Look for clothes labeled with an ultraviolet protection factor (UPF) of 40 to 50. Follow care instructions on the label of UV-blocking clothes to maintain their protective feature.

• #13 Polymorphous light eruption – Wikipedia

  https://en.wikipedia.org/wiki/Polymorphous_light_eruption

  Prevention: Sun protection (SPF 50+) […] Cover up with densely woven clothing. […] Management entails regulating triggers whilst simultaneously inducing „hardening”; that is, steadily increasing exposure to sunlight, as light sensitivity is reduced with repeated sun exposure. […] Covering up with densely woven clothing has also been shown to help, in addition to applying a broad-spectrum, water-resistant semi-opaque sun protection factor (SPF) 50+ sunblock cream before sun exposure and then every two hours thereafter confers some protection. […] The application of topical corticosteroids may lessen the redness and itch, and for preventing predictable holiday flare-ups, short courses of oral corticosteroids are sometimes considered. […] Another treatment option is a supervised course of low dose phototherapy, usually undertaken in winter.

• #14 Polymorphous light eruptions – Indian Journal of Skin Allergy

  https://skinallergyjournal.com/polymorphous-light-eruptions/

  Polymorphous light eruption (PMLE) is the most common, immunologically acquired photo-dermatosis due to delayed hypersensitivity reaction to sunlight. This review article focuses on immunopathogenesis, clinical features, and treatment options involved in PMLE. […] Management of PMLE includes photoprotective measures, systemic photoprotection, photo-hardening, and topical and oral corticosteroids. Photoprotective measures are fundamental in managing PLE. It includes the use of protective clothing, hats, and frequent application of sunscreens. Broad-spectrum sunscreens with a high sun protection factor against both UVA and UVB, along with physical sunscreens (zinc oxide and titanium oxide) are effective in preventing PLE eruptions. […] Photoprotective clothing plays an important role in the prevention of PMLE. UPF (UV protection factor) is used as an indicator for UV protective clothing. Patients are instructed to use full hand sleeves, shoes, sunglasses, scarves, and hats with a wider brim to protect the head, ears, neck, sides of the face, other sun-exposed parts, and to avoid tight-fitting clothes.

• #15 Preventing sun-related skin reactions in kids – CHOC – Children’s health hub

  https://health.choc.org/preventing-sun-related-skin-reactions-in-kids/

  Dress your child in lightweight, protective clothing that covers their skin, such as long sleeves, long pants, and a wide-brimmed hat. […] Educate your child about the importance of sun protection and reapplication of sunscreens. […] Encourage good habits in kids through positive reinforcement of behaviors such as seeking shade, wearing protective clothing and applying sunscreen.

• #16 Polymorphous light eruption Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/diseases-conditions/polymorphous-light-eruption

  Polymorphous light eruption (PMLE) is a common skin reaction in people who are sensitive to sunlight (ultraviolet light). […] Protecting your skin from the sun can help prevent PMLE symptoms: Avoid sun exposure during hours of peak sun ray intensity. Use sunscreen. Sun protection with broad spectrum sunblock that works against UVA rays is important. Apply generous amounts of sunscreen with a sun protection factor (SPF) of at least 30. Pay special attention to your face, nose, ears, and shoulders. Apply sunscreen 30 minutes before sun exposure so that it has time to penetrate the skin. Re-apply after swimming and every 2 hours while you are outdoors. Wear a sun hat. Wear sunglasses with UV protection. Use a lip balm with sunscreen.

• #17 Prevention of Polymorphic Light Eruption Afforded by a Very High Broad-Spectrum Protection Sunscreen Containing Ectoin

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9276854/

  Polymorphic light eruption (PLE) is the most common idiopathic, acquired photodermatosis. […] In the present study, a high broad-spectrum sunscreen medical device (MD), containing a very high protection complex of UVB and UVA filters and ectoin, was investigated for its ability to protect against UVA-induced PLE. […] This MD sunscreen based on a complex of UVAUVB filters and 1% of ectoin may be effective in preventing UVA-induced PLE. […] Therapy relies mainly on topical or systemic corticosteroids, but also on broad-spectrum sunscreens and antioxidants for prevention. […] According to the published literature on the PLE, avoidance of UV exposure and the use of high SPF broad-spectrum sunscreens with efficacy against both UVB and UVA can minimize the risk of photosensitivity effects.

• #18 Polymorphic light eruption (PLE) – British Skin Foundation

  https://knowyourskin.britishskinfoundation.org.uk/condition/polymorphic-light-eruption/

  Using oral or topical antioxidants as well as oral nicotinamide prior or after the first sun exposure has shown to prevent PLE. […] Spend time in the shade between 11am and 3pm when its sunny. […] When choosing a sunscreen look for a high protection SPF (SPF 50 or above) to protect against UVB, and the UVA circle logo and/or 4 or 5 UVA stars to protect against UVA. […] Sunscreens should not be used as an alternative to clothing and shade, rather they offer additional protection. […] Taking Vitamin D supplement tablets (available from health food shops) may be helpful as strictly avoiding sunlight can reduce Vitamin D levels.

• #19 Preventing sun-related skin reactions in kids – CHOC – Children’s health hub

  https://health.choc.org/preventing-sun-related-skin-reactions-in-kids/

  Polymorphous light eruption (PMLE), also known as “sun allergy” or “sun poisoning” is the most common type of photosensitivity. It often occurs one to two days after intense sun exposure. […] Topical steroids and/or antihistamines may be helpful for symptomatic relief. Lesions often disappear in one to two weeks spontaneously, if no further sun exposure occurs. […] To prevent these skin reactions and protect your child from the harmful effects of the sun, Dr. Guide recommends some additional tips: […] Consider using physical sunscreens that contain zinc oxide or titanium dioxide, as they provide a physical barrier against UV rays and are less likely to cause sensitivity in children prone to photosensitivity or allergies. […] Encourage your child to seek shade during peak sunlight hours, usually between 10 a.m. and 2 p.m., when the sun’s rays are the strongest.

• #20 FloridaHealthFinder | Polymorphous light eruption | Health Encyclopedia | FloridaHealthFinder

  https://quality.healthfinder.fl.gov/health-encyclopedia/HIE/1/001477

  Protecting your skin from the sun can help prevent PMLE symptoms: […] Avoid sun exposure during hours of peak sun ray intensity. […] Use sunscreen. Sun protection with broad spectrum sunblock that works against UVA rays is important. […] Apply generous amounts of sunscreen with a sun protection factor (SPF) of at least 30. Pay special attention to your face, nose, ears, and shoulders. […] Apply sunscreen 30 minutes before sun exposure so that it has time to penetrate the skin. Re-apply after swimming and every 2 hours while you are outdoors. […] Wear a sun hat. […] Wear sunglasses with UV protection. […] Use a lip balm with sunscreen.

• #21 Polymorphous Light Eruption Symptoms, Causes, and Treatment

  https://www.healthline.com/health/polymorphous-light-eruption

  To reduce the effects of PMLE, the American Academy of Dermatology (AAD) recommends seeking shade and applying sunscreen. If you can, avoid the sun when its at its strongest during the middle of the day. […] Experts recommend using sunscreen thats SPF 50, broad spectrum (meaning it blocks both UVA and UVB rays), and water-resistant. You should reapply every 2 hours. […] Additionally, the AAD suggests covering your skin from direct sun exposure. There are many clothing choices that can help you do this, such as: […] The best way to address PMLE is to avoid direct sun during the strongest parts of the day, wear appropriate sunscreen, and wear clothing that covers your skin. These are good practices for everyone, with or without PMLE.

• #22 Interventions for polymorphic light eruption

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6485352/

  To assess the effects of interventions in the prophylaxis and treatment of polymorphic light eruption. […] Preventive management is routinely advocated by sun avoidance between 11 a.m. and 3 p.m., use of protective clothing, and application of sunscreen. […] However, for more severe PLE sufferers, this is rarely adequate. […] The most common are: […] Topical steroids are widely used for mild episodes of PLE. […] An immediate short course of oral prednisolone considerably reduces the severity of itch and rash in people who suffer from occasional, severe attacks of PLE on vacation. […] PsoralenUVA (PUVA), narrowband (NBUVB) or broadband UVB (BBUVB) phototherapy is currently the mainstay of treatment for more severe PLE. […] A course may also be administered in early spring as a preventive treatment to induce skin tolerance for more severe PLE.

• #23 Polymorphic Light Eruption (PMLE): Causes and Treatment

  https://patient.info/doctor/polymorphic-light-eruption-pro

  Polymorphic light eruption treatment and management […] Prevention […] Methods include: […] Protection from sunlight – protective clothing and sunscreens (note that these may not filter out all sunlight). […] Allow gradual exposure to sunlight, which may acclimatise the skin and prevent the rash. […] Broad-spectrum sunscreens which are effective at blocking UVA are sometimes effective. […] One small trial in 2004 suggested effective prevention using certain antioxidants combined with sunscreen but this idea does not seem to have progressed since then and does not appear in guidelines. […] […] […] Severe PMLE […] This may be treated with: […] Prophylactic light therapy (before sun exposure – eg, in early spring), which may help. This is known as 'photohardening’ and aims to induce sunlight tolerance, using controlled exposure. This may use: UVB. UVA/UVB. Psoralen combined with UVA (PUVA) treatment. […] […] […] Most patients can control their PMLE with simple treatments. […] The condition is likely to ease as the spring and summer advance; however, it will probably recur the following year unless precautions are taken.

• #24 Successful short desensitization treatment protocol with narrowband UVB phototherapy (TL-01) in polymorphic light eruption | Actas Dermo-Sifiliográficas

  https://www.actasdermo.org/en-successful-short-desensitization-treatment-protocol-articulo-S1578219017302986

  Polymorphic light eruption (PLE) is a common idiopathic photodermatosis that typically presents with pruritic papular or papulovesicular lesions on sun-exposed skin between spring and autumn. In many subjects PLE is mild, and can usually be prevented by the use of broad-spectrum topical sunscreens and a gradual increase in sunlight exposure. However, in some individuals, sunlight exposure results in florid PLE and they often benefit from prophylactic desensitization treatment using phototherapy in early spring, an artificial method that induces a hardening phenomenon. […] The effect of hardening was maintained in the vast majority of subjects, obtaining a good benefit with no PLE episodes during all the summer. We demonstrate that our standard protocol is effective, and produces a successful outcome for the majority of PLE subjects. Our protocol is shorter than those currently applied, being favourable both for the patient and the physician. […] Treatment needs to be repeated yearly in early spring, as the photoprotective effects of phototherapy are temporary. There appears to be no loss of benefit with subsequent courses.

• #25 Polymorphous Light Eruption

  https://mobile.fpnotebook.com/Derm/Environ/PlymrphsLghtErptn.htm

  Sunscreen […] First-line measure, but not uniformly effective […] Apply SPF 50 Sunscreens every 2 hours to exposed skin […] […] Prophylaxis […] Beta Carotene […] Take 60 mg orally three times daily for 2 weeks before Sun Exposure […] […] PUVA and Narrow Band UVB at 311 nm […] Given in early spring (before sunny season) to induce tolerance […] Annual treatment with 2-3 sessions per week for 4 to 6 weeks (for 3-4 years) […] […] Corticosteroids […] Prednisone 20 mg/day starting 2 days before and continuing for 2 days after start of Sun Exposure OR […] Triamcinolone Acetonide 40 mg IM given 2 days prior to travel to sunny region

• #26 Polymorphous Light Eruption: Practice Essentials, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/1119686-overview

  Management of PMLE includes strict sun protection. This can be accomplished by using broad-spectrum sunscreens, seeking shade, and wearing protective clothing, including hats. […] Photohardening is beneficial and can be initiated early in spring to enhance tolerance of sun exposure. […] Prophylactic PUVA and UVB therapy in polymorphic light eruption–a controlled trial. […] A new ecamsule-containing SPF 40 sunscreen cream for the prevention of polymorphous light eruption: a double-blind, randomized, controlled study in maximized outdoor conditions. […] Influence of the quantity of sunscreen applied on the ability to protect against ultraviolet-induced polymorphous light eruption. […] Oral administration of a hydrophilic extract of Polypodium leucotomos for the prevention of polymorphic light eruption. […] Polymorphous light eruption (PLE) and a new potent antioxidant and UVA-protective formulation as prophylaxis.

• #27 Polymorphic light eruption

  https://www.nhs.uk/conditions/polymorphic-light-eruption/

  Reapply every 2 hours and straight after you’ve dried yourself off after swimming. […] It’s sometimes possible to increase the resistance of your skin to the sun. […] This involves visiting a hospital dermatology department 3 times a week for 4 to 6 weeks in the spring. […] Your skin is gradually exposed to a little more UV light every visit to try to build up your skin’s resistance. […] A GP or dermatologist may advise you to try increasing the resistance of your skin at home. […] This is known as „hardening” and involves going outside for short periods in the spring to build up your resistance. […] People with polymorphic light eruption are at greater risk of vitamin D deficiency, as a certain amount of sun exposure is needed to make your own vitamin D.

• #28

  https://sunsaferx.com/blogs/health-wellness/polymorphous-light-eruption-treatment-prevention?srsltid=AfmBOoqPCVXgcv1MivLvg5RGn85UkTitITrCSeyE-WOuKuKo7z7OB2–

  The key to preventing polymorphous light eruption, and to preventing recurring episodes, is to protect your skin from sun exposure. […] To prevent PLE: […] Avoid sun exposure […] At the very least avoid exposure in the middle of the day when UVB rays are highest in intensity. However, the intensity of UVA rays is relatively unchanged all day (and UVA rays can cause PLE reactions) so limit sun exposure even in the evenings. […] Cover up […] Wear a hat and sunglasses, long-sleeve shirt and pants, and cover as much exposed skin as possible. […] Use sunscreen lotion prior to sun exposure […] Use sunscreen to help prevent PMLE. […] Try gradual sun exposure […] Over days, weeks, and months, some people with PLE have success slowly exposing their skin to increasing amounts of sunlight. […] Moisturize your skin […] Dry skin can irritate PLE and make it worse. […] Use An Antioxidant Nutritional Supplement […] Sunsafe Rx is a natural nutritional supplement made with ingredients that have been clinically shown to help protect your skin from the adverse effects of the environment.

• #29 Dermatology – Polymorphic Light Eruption :: Northern Care Alliance

  https://www.northerncarealliance.nhs.uk/patient-information/patient-leaflets/dermatology-polymorphic-light-eruption?q=%2Fpatient-information%2Fpatient-leaflets%2Fdermatology-polymorphic-light-eruption

  Learn how much sunlight your skin can tolerate and keep within that limit […] Make sure you introduce your skin to sunlight gradually in the spring. […] You will be provided with sunscreens on prescription, and these will help prevent the rash developing. Sunscreen should be applied as thickly and evenly as possible and re-applied often. […] Sometimes the resistance of your skin to the effects of the sun can be increased. This is done in a hospital department and will involve visiting the hospital three times a week for about 5 weeks in the spring. […] Some people with PLE may be able to increase the resistance of their skin at home. This involves going outside for short periods in the spring to build up your resistance. […] There is some research suggesting that fish oil rich in omega 3 oils can help some patients with PLE. […] Some research has also suggested that another supplement, Polypodium leucotomos extract (Fernblock in Heliocare tablets), can be helpful in some cases.

• #30 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Polymorphic-Light-Eruption-(PLE)-Rash-Associated-with-Sun-Exposure.aspx

  As polymorphic light eruption is directly related to sunlight exposure, it is sensible for people who suffer from the condition to protect their skin from the sun. Way of doing this include: […] Wearing a hat and long-sleeved clothes when intending to partake in outdoor activities in the sun. […] Using sunscreen (at least SPF 30+) to protect skin when in the sun. […] Limit time in the sun between 11am and 3pm when the sunrays are strongest. […] It is also possible for skin to acquire resistance to sun exposure. Many people find that gradually building up sun exposure each day allows their skin to become accustomed to the sunlight and avoid the effect of the rash. Ideally, this should be done in spring, spending 5 minutes in the sun each day and gradually building up to as long as individuals need in the sun.

• #31 Interventions for polymorphic light eruption

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6485352/

  There are many reported treatments for PLE. Sun protection, corticosteroids and desensitisation phototherapy appear to be the current mainstay of treatment, with immunomodulator agents as secondline treatment. […] In all treatments, the therapeutic benefits need to be weighed against the potential side effects. […] Interventions to be assessed in this review include: […] behavioural (clothing, environmental, and topical sunscreen, i.e. sunlight protection measures); […] corticosteroids (topical and oral). […] Other possible immunomodulators and antiinflammatory agents (nicotinamide, live attenuated E. coli extract, dead E. coli extract, dietary fish oil, betacarotene, antioxidants, and others).

• #32 Recognizing and preventing sun allergies – Harvard Health

  https://www.health.harvard.edu/blog/recognizing-and-preventing-sun-allergies-202207052772

  PMLE is more common in young women who live in temperate climates. […] The best treatment is to prevent sun exposure. Avoid sunlight when it is most intense (from 10 a.m. to 4 p.m.), and use UV-protecting clothing or clothes made of darker and thicker fabrics, as they will prevent the UV rays coming from the sun from reaching your skin. […] Oral Polypodium leucotomos extract, a natural substance derived from tropical fern leaves, may work as a potent antioxidant, and has anti-inflammatory properties that are beneficial in the prevention of PMLE. […] Sun allergies are common in temperate climates, but with a dermatologist’s guidance, vigilant sun prevention, and medications they can be managed throughout the sunny months of the year.

• #33 Dermatology – Polymorphic Light Eruption :: Northern Care Alliance

  https://www.northerncarealliance.nhs.uk/patient-information/patient-leaflets/dermatology-polymorphic-light-eruption?q=%2Fpatient-information%2Fpatient-leaflets%2Fdermatology-polymorphic-light-eruption

  Learn how much sunlight your skin can tolerate and keep within that limit […] Make sure you introduce your skin to sunlight gradually in the spring. […] You will be provided with sunscreens on prescription, and these will help prevent the rash developing. Sunscreen should be applied as thickly and evenly as possible and re-applied often. […] Sometimes the resistance of your skin to the effects of the sun can be increased. This is done in a hospital department and will involve visiting the hospital three times a week for about 5 weeks in the spring. […] Some people with PLE may be able to increase the resistance of their skin at home. This involves going outside for short periods in the spring to build up your resistance. […] There is some research suggesting that fish oil rich in omega 3 oils can help some patients with PLE. […] Some research has also suggested that another supplement, Polypodium leucotomos extract (Fernblock in Heliocare tablets), can be helpful in some cases.

• #34 Polymorphous light eruption – Symptoms, Causes, Images, and Treatment Options

  https://www.epocrates.com/online/diseases/626/polymorphous-light-eruption

  Polymorphous light eruption typically onsets during adolescence and young adulthood. […] Topical corticosteroid creams or lotions are the mainstay of therapy, with the addition of oral corticosteroids and nonsteroidal anti-inflammatory drugs (NSAIDs) in severe disease. […] Hadshiew IM, Treder-Conrad C, v. Blow R, et al. Polymorphous light eruption (PLE) and a new potent antioxidant and UVA-protective formulation as prophylaxis. Photodermatol Photoimmunol Photomed. 2004 Aug;20(4):200-4. […] Marini A, Jaenicke T, Grether-Beck S, et al. Prevention of polymorphic light eruption by oral administration of a nutritional supplement containing lycopene, beta-carotene, and Lactobacillus johnsonii: results from a randomized, placebo-controlled, double-blinded study. Photodermatol Photoimmunol Photomed. 2014 Aug;30(4):189-94.

• #35 Photosensitivity Reactions – Skin Disorders – Merck Manual Consumer Version

  https://www.merckmanuals.com/home/skin-disorders/sunlight-and-skin-damage/photosensitivity-reactions

  Polymorphous light eruption is a reaction to sunlight (primarily UVA light) that is not fully understood. It is one of the most common sun-related skin problems and is most common among women and among people from northern climates who are not regularly exposed to the sun. […] The eruption usually goes away within several days to weeks. Typically, people with this condition who continue to go out in the sun gradually become less sensitive to the effects of sunlight (a process known as hardening). […] For polymorphous light eruption, corticosteroids or hydroxychloroquine and sometimes UV light exposure. […] People with polymorphous light eruption or photosensitivity caused by systemic lupus erythematosus (lupus) may benefit from corticosteroids applied to the skin or hydroxychloroquine or corticosteroids taken by mouth. Occasionally, people with polymorphous light eruption can be desensitized to the effects of sunlight by gradually increasing their exposure to UV light. […] Taking Polypodium leucotomos (a dietary supplement made from certain tropical ferns) or nicotinamide (a form of vitamin B3) by mouth may be helpful in preventing symptoms in people susceptible to photosensitivity caused by sun exposure.

• #36 Interventions for polymorphic light eruption

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6485352/

  To assess the effects of interventions in the prophylaxis and treatment of polymorphic light eruption. […] Preventive management is routinely advocated by sun avoidance between 11 a.m. and 3 p.m., use of protective clothing, and application of sunscreen. […] However, for more severe PLE sufferers, this is rarely adequate. […] The most common are: […] Topical steroids are widely used for mild episodes of PLE. […] An immediate short course of oral prednisolone considerably reduces the severity of itch and rash in people who suffer from occasional, severe attacks of PLE on vacation. […] PsoralenUVA (PUVA), narrowband (NBUVB) or broadband UVB (BBUVB) phototherapy is currently the mainstay of treatment for more severe PLE. […] A course may also be administered in early spring as a preventive treatment to induce skin tolerance for more severe PLE.

• #37 Polymorphic Light Eruption | Treatment & Management | Point of Care

  https://www.statpearls.com/point-of-care/34016

  There is some evidence to support prophylactic short courses of oral steroids (for example, to prevent the eruption during a holiday break), hydroxychloroquine, and antioxidants such as Polypodium leucotomes extract, lycopene, beta-carotene, nicotinamide and astaxanthin. […] The eruption is treated with topical corticosteroids with some benefit in reducing symptoms and duration. […] These healthcare professionals should educate the patients on prevention which includes wearing appropriate garments when going outside and use ample sunscreen frequently.

• #38 Polymorphous Light Eruption

  https://mobile.fpnotebook.com/Derm/Environ/PlymrphsLghtErptn.htm

  Sunscreen […] First-line measure, but not uniformly effective […] Apply SPF 50 Sunscreens every 2 hours to exposed skin […] […] Prophylaxis […] Beta Carotene […] Take 60 mg orally three times daily for 2 weeks before Sun Exposure […] […] PUVA and Narrow Band UVB at 311 nm […] Given in early spring (before sunny season) to induce tolerance […] Annual treatment with 2-3 sessions per week for 4 to 6 weeks (for 3-4 years) […] […] Corticosteroids […] Prednisone 20 mg/day starting 2 days before and continuing for 2 days after start of Sun Exposure OR […] Triamcinolone Acetonide 40 mg IM given 2 days prior to travel to sunny region

• #39 Polymorphous Light Eruption: A Review

  https://scholarlycommons.henryford.com/dermatology_articles/367/

  PMLE is known to be the most common photodermatosis seen in individuals with light skin types; however, recent evidence shows that it is also commonly observed in individuals with skin of color. […] Photohardening, done at the onset of sunny season for patients living in temperate climate, is a commonly used and effective management. […] Management includes photoprotection and photohardening. […] A 710-day course of oral corticosteroids is an appropriate prophylaxis for patients who plan to go to sunny locale for vacation.

• #40 Polymorphic Light Eruption | Treatment & Management | Point of Care

  https://www.statpearls.com/point-of-care/34016

  There is some evidence to support prophylactic short courses of oral steroids (for example, to prevent the eruption during a holiday break), hydroxychloroquine, and antioxidants such as Polypodium leucotomes extract, lycopene, beta-carotene, nicotinamide and astaxanthin. […] The eruption is treated with topical corticosteroids with some benefit in reducing symptoms and duration. […] These healthcare professionals should educate the patients on prevention which includes wearing appropriate garments when going outside and use ample sunscreen frequently.

• #41 Polymorphic light eruption (PMLE) — DermNet

  https://dermnetnz.org/topics/polymorphic-light-eruption

  Polymorphic light eruption (PMLE) is a seasonal, acquired, idiopathic photodermatosis occurring in spring and early summer. […] Patients with PMLE can develop a tolerance during summer months. […] The following factors must be considered when determining pathogenesis and when implementing protective measures: It is primarily caused by either UVA (7590%) or UVB light alone or UVA and UVB light concurrently. […] General measures include broad-spectrum 50+ SPF UVA/UVB sunscreen, sun protective clothing, and avoiding sunlight, choosing shaded areas if outdoors and sitting away from windows. […] Specific measures include topical calcipotriol which may be useful as prophylaxis prior to sun exposure. […] If severe, systemic immunosuppressants such as azathioprine or ciclosporin (cyclosporine) may be considered.

• #42 Polymorphic light eruption (PMLE) — DermNet

  https://dermnetnz.org/topics/polymorphic-light-eruption

  Polymorphic light eruption (PMLE) is a seasonal, acquired, idiopathic photodermatosis occurring in spring and early summer. […] Patients with PMLE can develop a tolerance during summer months. […] The following factors must be considered when determining pathogenesis and when implementing protective measures: It is primarily caused by either UVA (7590%) or UVB light alone or UVA and UVB light concurrently. […] General measures include broad-spectrum 50+ SPF UVA/UVB sunscreen, sun protective clothing, and avoiding sunlight, choosing shaded areas if outdoors and sitting away from windows. […] Specific measures include topical calcipotriol which may be useful as prophylaxis prior to sun exposure. […] If severe, systemic immunosuppressants such as azathioprine or ciclosporin (cyclosporine) may be considered.

• #43 Reddit – The heart of the internet

  https://www.reddit.com/r/pmle/comments/wqw6yo/found_a_solution_hopefully_to_my_horrible_pmle/

  Hydroxychloroquine seems to work. […] I need to find a balance of what to keep from my old routine and this medication. […] It might not work for you or be the best option for you, but definitely talk to your doctor about the possibility if your PMLE has become disabling like mine had.

• #44 Prevention of Polymorphic Light Eruption Afforded by a Very High Broad-Spectrum Protection Sunscreen Containing Ectoin

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9276854/

  Polymorphic light eruption (PLE) is the most common idiopathic, acquired photodermatosis. […] In the present study, a high broad-spectrum sunscreen medical device (MD), containing a very high protection complex of UVB and UVA filters and ectoin, was investigated for its ability to protect against UVA-induced PLE. […] This MD sunscreen based on a complex of UVAUVB filters and 1% of ectoin may be effective in preventing UVA-induced PLE. […] Therapy relies mainly on topical or systemic corticosteroids, but also on broad-spectrum sunscreens and antioxidants for prevention. […] According to the published literature on the PLE, avoidance of UV exposure and the use of high SPF broad-spectrum sunscreens with efficacy against both UVB and UVA can minimize the risk of photosensitivity effects.

• #45 Prevention of Polymorphic Light Eruption Afforded by a Very High Broad-Spectrum Protection Sunscreen Containing Ectoin

  https://pmc.ncbi.nlm.nih.gov/articles/PMC9276854/

  The combination of a very high UVB and UVA protection combined with ectoin provides very effective prevention of UVA-induced PLE. […] In conclusion, this MD sunscreen, based on a complex of UVAUVB filters and 1% of ectoin, may be effective in preventing UVA-induced PLE, but new studies comparing this MD sunscreen versus the same product without ectoin should be conducted.

• #46

  https://link.springer.com/article/10.1007/s13555-022-00755-5

  According to the published literature on the PLE, avoidance of UV exposure and the use of high SPF broad-spectrum sunscreens with efficacy against both UVB and UVA can minimize the risk of photosensitivity effects. […] The objective of the present study was to assess the photo protective efficacy of a medical device (MD) FOTO ULTRA ISDIN SOLAR ALLERGY FUSION FLUID (ISDIN SA, Barcelona Spain) against UVA-induced PLE. […] In conclusion, this MD sunscreen, based on a complex of UVAUVB filters and 1% of ectoin, may be effective in preventing UVA-induced PLE, but new studies comparing this MD sunscreen versus the same product without ectoin should be conducted.

• #47

  https://link.springer.com/article/10.1007/s13555-022-00755-5

  Polymorphic light eruption (PLE) is the most common idiopathic, acquired photodermatosis. […] In the present study, a high broad-spectrum sunscreen medical device (MD), containing a very high protection complex of UVB and UVA filters and ectoin, was investigated for its ability to protect against UVA-induced PLE. […] This MD sunscreen based on a complex of UVAUVB filters and 1% of ectoin may be effective in preventing UVA-induced PLE. […] We assessed the efficacy of a high broad-spectrum sunscreen containing ectoin, a lipid raft stabilizer osmolyte, to prevent UVA-induced PLE. […] The combination of a very high UVB and UVA protection combined with ectoin provides very effective prevention of UVA-induced PLE. […] Therapy relies mainly on topical or systemic corticosteroids, but also on broad-spectrum sunscreens and antioxidants for prevention.

• #48 Prevention of Polymorphous Light Eruption and Solar Urticaria

  https://www.skintherapyletter.com/urticaria/polymorphous-light-eruption/

  Prophylactic treatments with UVA, UVB or PUVA therapy can prevent PLE in certain patients. Although PUVA therapy is effective, its use has to be weighed against the risks of squamous cell carcinoma and melanoma. A topical formulation containing the antioxidants tocopheryl acetate, ferulic acid and α-glycosylrutin was reported to prevent the development and reduce the severity of indoor PLE in certain patients, suggesting that the role of antioxidants in sunscreen formulations deserves further study. […] In conclusion, PLE and solar urticaria can be prevented in most patients by decreasing their amount of sun exposure and by using an adequate sunscreen. As UVA is mainly involved in the induction of both diseases, the sunscreen used should contain broad as well as high UVA protection.

• #49

  https://www.shirudo.com/blogs/pages/prevent-polymorphous-light-eruption-pmle?srsltid=AfmBOoqQqW6PYPx2bJVKJewMsgod-VUVoYx97BuieVBEB7ePQDxqLMxD

  Polymorphous Light Eruption or PMLE is the most common sun allergy, affecting 10% to 15% of North Americans. […] Use Shirudo AGR+E lotion 15 minutes prior to sun exposure with a broad spectrum sunscreen, and repeat every two hours. […] According to studies, a formulation combining alpha-glucosylrutin (AGR) and Vitamin E use with a broad spectrum sunscreen is an effective preventive treatment for Polymorphous Light Eruption. In clinical studies, 80% of people who have used this formulation have experienced a major improvement of their PMLE and most of them had no symptoms at all. […] From all the preventive PMLE treatments I’ve tried so far, it is the only solution that has reduced 90% of my symptoms and allowed me to fully enjoy a sun vacation for the first time since I was 12 years old.

• #50 Sun Allergy | Symptoms, Causes & Prevention | La Roche-Posay

  https://www.laroche-posay.sg/article/sun-allergy-symptoms-causes-and-how-to-deal-with-it

  Sun allergy or polymorphous light eruption is caused by exposure to sunlight, especially UVA rays. […] The primary treatment for sun allergy is prevention. That means limiting sun exposure with smart sun protection habits and the right sunscreen for sun allergy. To avoid sun allergy, follow these simple tips: Avoid being out in the sun between 11:00 and 16:00. Wear protective clothing such as hats, sunglasses, long-sleeved t-shirts, etc. Use sun protection creams with a very high protection factor (SPF 50+) and broad spectrum anti-UVB and anti-UVA protection. Ensure your sunscreen also protects against long UVA (not all do!). Make sure your sunscreen is created for sensitive, reactive and allergy-prone skin to avoid reactions. Re-apply a suitable sunscreen every two hours. […] If you suffer from any form of sun allergy, you need to find the right sunscreen. The dermatologists partner brand La Roche-Posay develops specialist sun care products for people with skin conditions such as sun allergy. ANTHELIOS Med Sun Intolerance cream is the 1st sunscreen with high broad-spectrum UVA + UVB protection, combined with an anti-pruritus (anti-itch) action thanks to skin-calming Neurosensine. It is specifically created for sensitive and sun-intolerant skin prone to sun allergies such as polymorphous light eruption. ANTHELIOS Med Sun Intolerance offers clinically proven efficacy on patients at risk of polymorphous light eruption.

• #51 Preventing Polymorphous Light Eruption: Sun Protection Tips for Outdoor Activities

  https://www.darwynhealth.com/skin-health/skin-disorders/sunlight-and-skin-damage/polymorphous-light-eruption/preventing-polymorphous-light-eruption-sun-protection-tips-for-outdoor-activities/?lang=en

  Polymorphous light eruption (PLE) is a common skin condition triggered by sun exposure. By following these tips, you can minimize the risk of developing PLE and enjoy your time outside without worrying about skin reactions. Here are some practical tips to help you protect your skin from the harmful effects of the sun: Applying sunscreen is crucial in shielding your skin from harmful UV rays. Look for a broad-spectrum sunscreen with an SPF of 30 or higher. By following these sun protection tips, you can significantly reduce the risk of developing PLE and enjoy outdoor activities with peace of mind. Wearing protective clothing plays a crucial role. By covering your skin with appropriate clothing, you can significantly reduce your exposure to harmful ultraviolet (UV) radiation. To effectively protect yourself from the sun, it is important to cover as much of your body as possible. Seeking shade during peak sun hours is crucial for reducing sun exposure and minimizing the risk of Polymorphous Light Eruption (PLE). By incorporating these shade-seeking strategies into your outdoor activities, you can significantly reduce your sun exposure and lower the risk of developing PLE. Proper hydration plays a crucial role in protecting your skin from the harmful effects of the sun. By staying hydrated, you can maintain the natural moisture barrier of your skin, keeping it healthy and resilient. Remember, staying hydrated is not only important for your overall health but also for protecting your skin from the damaging effects of the sun. Learn how to prevent polymorphous light eruption (PLE) and protect your skin from the sun’s harmful rays during outdoor activities. Follow these sun protection tips to minimize the risk of developing PLE and enjoy your time outside without worrying about skin reactions.

• #52

  https://www.dermatologycenterofwellington.com/blog/polymorphous-light-eruption-learn-who-is-affected-and-recognize-the-symptoms-1

  Polymorphous Light Eruption (PMLE) is a sensitivity to the sun, commonly referred to as a sun allergy. […] While you may not be able to completely prevent all symptoms of this photosensitivity skin issue, you may be able to control it or prevent the eruptions from recurring. The best course of prevention is to avoid direct contact with the sun. This may not always be possible, but you should reduce your exposure as much as possible. For starters stay in the shade when outdoors and always use sunscreen to exposed skin. Those with sensitivity to the sun should also cover up by wearing long sleeves and long pants whenever possible. You might also wear a wide brimmed hat when venturing outdoors. […] You may also want to alter your lifestyle a bit as well. This may include being mindful of exposing your hands and arms to sunlight, which may enter through car windows as you ride in the car. Sitting under a beach umbrella and wearing cover-ups at the beach is another good idea.

• #53 Preventing Polymorphous Light Eruption: Sun Protection Tips for Outdoor Activities

  https://www.darwynhealth.com/skin-health/skin-disorders/sunlight-and-skin-damage/polymorphous-light-eruption/preventing-polymorphous-light-eruption-sun-protection-tips-for-outdoor-activities/?lang=en

  Polymorphous light eruption (PLE) is a common skin condition triggered by sun exposure. By following these tips, you can minimize the risk of developing PLE and enjoy your time outside without worrying about skin reactions. Here are some practical tips to help you protect your skin from the harmful effects of the sun: Applying sunscreen is crucial in shielding your skin from harmful UV rays. Look for a broad-spectrum sunscreen with an SPF of 30 or higher. By following these sun protection tips, you can significantly reduce the risk of developing PLE and enjoy outdoor activities with peace of mind. Wearing protective clothing plays a crucial role. By covering your skin with appropriate clothing, you can significantly reduce your exposure to harmful ultraviolet (UV) radiation. To effectively protect yourself from the sun, it is important to cover as much of your body as possible. Seeking shade during peak sun hours is crucial for reducing sun exposure and minimizing the risk of Polymorphous Light Eruption (PLE). By incorporating these shade-seeking strategies into your outdoor activities, you can significantly reduce your sun exposure and lower the risk of developing PLE. Proper hydration plays a crucial role in protecting your skin from the harmful effects of the sun. By staying hydrated, you can maintain the natural moisture barrier of your skin, keeping it healthy and resilient. Remember, staying hydrated is not only important for your overall health but also for protecting your skin from the damaging effects of the sun. Learn how to prevent polymorphous light eruption (PLE) and protect your skin from the sun’s harmful rays during outdoor activities. Follow these sun protection tips to minimize the risk of developing PLE and enjoy your time outside without worrying about skin reactions.

• #54 Polymorphous Light Eruption

  https://www.darwynhealth.com/skin-health/skin-disorders/sunlight-and-skin-damage/polymorphous-light-eruption/?lang=en

  Polymorphous light eruption (PMLE) is a common skin condition that affects individuals who are sensitive to sunlight. […] To manage PMLE, it is important to avoid excessive sun exposure and protect the skin from harmful UV rays. This can be done by wearing protective clothing, such as long sleeves and wide-brimmed hats, and using broad-spectrum sunscreen with a high SPF. […] Preventing PMLE flare-ups is key to managing the condition. Gradual sun exposure, starting with short periods of time and gradually increasing, can help the skin become more tolerant to sunlight. […] If you suspect you have PMLE, it is recommended to consult with a dermatologist for an accurate diagnosis and appropriate treatment plan. […] By taking preventive measures and seeking medical advice, individuals with PMLE can effectively manage the condition and enjoy time outdoors without experiencing flare-ups. […] In this article, we will discuss effective sun protection tips to prevent PLE during outdoor activities. By following these tips, you can minimize the risk of developing PLE and enjoy your time outside without worrying about skin reactions.

• #55 Polymorphic light eruption

  https://www.nhs.uk/conditions/polymorphic-light-eruption/

  Reapply every 2 hours and straight after you’ve dried yourself off after swimming. […] It’s sometimes possible to increase the resistance of your skin to the sun. […] This involves visiting a hospital dermatology department 3 times a week for 4 to 6 weeks in the spring. […] Your skin is gradually exposed to a little more UV light every visit to try to build up your skin’s resistance. […] A GP or dermatologist may advise you to try increasing the resistance of your skin at home. […] This is known as „hardening” and involves going outside for short periods in the spring to build up your resistance. […] People with polymorphic light eruption are at greater risk of vitamin D deficiency, as a certain amount of sun exposure is needed to make your own vitamin D.

• #56 Polymorphic light eruption (PLE) – British Skin Foundation

  https://knowyourskin.britishskinfoundation.org.uk/condition/polymorphic-light-eruption/

  Using oral or topical antioxidants as well as oral nicotinamide prior or after the first sun exposure has shown to prevent PLE. […] Spend time in the shade between 11am and 3pm when its sunny. […] When choosing a sunscreen look for a high protection SPF (SPF 50 or above) to protect against UVB, and the UVA circle logo and/or 4 or 5 UVA stars to protect against UVA. […] Sunscreens should not be used as an alternative to clothing and shade, rather they offer additional protection. […] Taking Vitamin D supplement tablets (available from health food shops) may be helpful as strictly avoiding sunlight can reduce Vitamin D levels.

• #57 Polymorphic light eruption – BAD Patient Hub

  https://www.skinhealthinfo.org.uk/condition/polymorphic-light-eruption/

  Strictly follow the top sun safety tips as well as the vitamin D advice mentioned below. […] When choosing a sunscreen look for a high protection SPF (SPF 50 or above) to protect against UVB, and the UVA circle logo and/or 4 or 5 UVA stars to protect against UVA. […] Sunscreens should not be used as an alternative to clothing and shade, rather they offer additional protection. No sunscreen will provide 100% protection.

• #58 Polymorphous light eruptions – Indian Journal of Skin Allergy

  https://skinallergyjournal.com/polymorphous-light-eruptions/

  Studies have found that broad-spectrum sunscreens with 1% ectoin may be effective in preventing skin eruptions of PMLE. Systemic photoprotection: Oral antioxidants act as a free radical scavenger which can be used in the prevention of PMLE. […] Natural photo-hardening with gradual exposure to sunlight can prevent the eruption of skin lesions in milder variants of PMLE. Others: Vitamin D3 and its analogs (calcipotriol) have preventive and therapeutic effects in PMLE by immunosuppressive properties. […] The principles in preventing PMLE include counseling about photoprotective measures and proper use and application of sunscreens.

• #59

  https://journals.lww.com/idoj/fulltext/2021/12020/polymorphous_light_eruption__an_indian_scenario.1.aspx

  In India, most of the sunscreens available are combination products which include physical and chemical sunscreens. […] The use of an umbrella can be very useful. The patients should wear a dress covering the exposed areas to provide sun protection. […] Treatment should be based on the age, sex, occupation, and site of involvement. […] The management designed individually to suit the patients can be successful in the treatment and prevention of the disease.

• #60 Dermatology – Polymorphic Light Eruption :: Northern Care Alliance

  https://www.northerncarealliance.nhs.uk/patient-information/patient-leaflets/dermatology-polymorphic-light-eruption?q=%2Fpatient-information%2Fpatient-leaflets%2Fdermatology-polymorphic-light-eruption

  This guide has been written to help answer some of your questions about polymorphic light eruption. […] No treatment will get rid of PLE for ever but by careful sun avoidance and use of sunscreens the rash can often be prevented, and there are treatments that can help (see below). […] You should try to: […] Avoid the sun during conditions that provoke your photosensitivity and particularly when sunlight is intense. In the UK this is mainly between 11 and 3pm, although other times of day can be troublesome […] Wear protective clothing, with close/tightly woven fabrics, long sleeves and trousers, hats with broad brims. Glasses and sunglasses with wrap around lenses can also be helpful […] Use a sunscreen that is SPF 30 or above (high UVB protection) and also has high UVA protection. Remember to re-apply the sunscreen evenly and often

• #61 Dermatology – Polymorphic Light Eruption :: Northern Care Alliance

  https://www.northerncarealliance.nhs.uk/patient-information/patient-leaflets/dermatology-polymorphic-light-eruption?q=%2Fpatient-information%2Fpatient-leaflets%2Fdermatology-polymorphic-light-eruption

  Learn how much sunlight your skin can tolerate and keep within that limit […] Make sure you introduce your skin to sunlight gradually in the spring. […] You will be provided with sunscreens on prescription, and these will help prevent the rash developing. Sunscreen should be applied as thickly and evenly as possible and re-applied often. […] Sometimes the resistance of your skin to the effects of the sun can be increased. This is done in a hospital department and will involve visiting the hospital three times a week for about 5 weeks in the spring. […] Some people with PLE may be able to increase the resistance of their skin at home. This involves going outside for short periods in the spring to build up your resistance. […] There is some research suggesting that fish oil rich in omega 3 oils can help some patients with PLE. […] Some research has also suggested that another supplement, Polypodium leucotomos extract (Fernblock in Heliocare tablets), can be helpful in some cases.

• #62

  https://journals.lww.com/idoj/fulltext/2021/12020/polymorphous_light_eruption__an_indian_scenario.1.aspx

  In India, most of the sunscreens available are combination products which include physical and chemical sunscreens. […] The use of an umbrella can be very useful. The patients should wear a dress covering the exposed areas to provide sun protection. […] Treatment should be based on the age, sex, occupation, and site of involvement. […] The management designed individually to suit the patients can be successful in the treatment and prevention of the disease.

• #63 Polymorphic Light Eruption | Treatment & Management | Point of Care

  https://www.statpearls.com/point-of-care/34016

  There is some evidence to support prophylactic short courses of oral steroids (for example, to prevent the eruption during a holiday break), hydroxychloroquine, and antioxidants such as Polypodium leucotomes extract, lycopene, beta-carotene, nicotinamide and astaxanthin. […] The eruption is treated with topical corticosteroids with some benefit in reducing symptoms and duration. […] These healthcare professionals should educate the patients on prevention which includes wearing appropriate garments when going outside and use ample sunscreen frequently.

• #64 Interventions for polymorphic light eruption

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6485352/

  There are many reported treatments for PLE. Sun protection, corticosteroids and desensitisation phototherapy appear to be the current mainstay of treatment, with immunomodulator agents as secondline treatment. […] In all treatments, the therapeutic benefits need to be weighed against the potential side effects. […] Interventions to be assessed in this review include: […] behavioural (clothing, environmental, and topical sunscreen, i.e. sunlight protection measures); […] corticosteroids (topical and oral). […] Other possible immunomodulators and antiinflammatory agents (nicotinamide, live attenuated E. coli extract, dead E. coli extract, dietary fish oil, betacarotene, antioxidants, and others).

• #65 Prevention of Polymorphous Light Eruption and Solar Urticaria

  https://www.skintherapyletter.com/urticaria/polymorphous-light-eruption/

  Polymorphous light eruption is a common photodermatosis with a prevalence as high as 10-20% in Caucasian populations. Because PLE is a self-limited disease that spontaneously resolves when exposure to triggering light is stopped, the focus is centered on prevention. Sun protection and sun avoidance are central for PLE prevention. The level of photoprotection necessary to avoid the development of the eruption varies from patient to patient. For most patients with mild disease, avoidance of intense sun exposure, especially in the winter or early spring is sufficient to prevent the eruption. However, for some patients, seeking the shade and avoidance of intense sun exposure is not enough. Sunscreens have been recommended for these patients even though efficacy of earlier sunscreens has been low, probably because of their limited UVA protection.

• #66 Prevention of Polymorphic Light Eruption with a Sunscreen of Very High Protection Level Against UVB and UVA Radiation Under Standardized Photodiagnostic Conditions | HTML | Acta Dermato-Venereologica

  https://www.medicaljournals.se/acta/content/html/10.2340/00015555-0509

  The most effective prophylaxis of PLE is the application of ultraviolet (UV) protective clothing, but this is not suitable for areas such as the face or hands. […] The disadvantages of these treatment modalities are time-intensiveness or side-effects caused by the different treatment modalities. […] As the majority of sunscreens protect mainly from UVB, but fail to protect from UVA, they cannot sufficiently prevent patients from developing PLE. […] Thus, many sunscreens are not useful in the prevention of PLE and may even aggravate the disease. […] The data from the current study show that regular application of the sunscreen tested, which has very high protection levels in both the UVB and the UVA range, is able to prevent development of PLE lesions in all individuals showing positive PLE photoprovocation in the placebo control arm. […] Further studies are needed to confirm this highly effective prevention of PLE when applied under daily conditions of sun-exposure.

• #67 Polymorphous Light Eruption: Practice Essentials, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/1119686-overview

  Management of PMLE includes strict sun protection. This can be accomplished by using broad-spectrum sunscreens, seeking shade, and wearing protective clothing, including hats. […] Photohardening is beneficial and can be initiated early in spring to enhance tolerance of sun exposure. […] Prophylactic PUVA and UVB therapy in polymorphic light eruption–a controlled trial. […] A new ecamsule-containing SPF 40 sunscreen cream for the prevention of polymorphous light eruption: a double-blind, randomized, controlled study in maximized outdoor conditions. […] Influence of the quantity of sunscreen applied on the ability to protect against ultraviolet-induced polymorphous light eruption. […] Oral administration of a hydrophilic extract of Polypodium leucotomos for the prevention of polymorphic light eruption. […] Polymorphous light eruption (PLE) and a new potent antioxidant and UVA-protective formulation as prophylaxis.

• #68 Polymorphic Light Eruption | Treatment & Management | Point of Care

  https://www.statpearls.com/point-of-care/34016

  Management requires determining what provokes the eruption and then attempting to minimize this, while at the same time gradually increasing exposure to induce hardening. […] Explain that UV-A is a large component of sunlight and can cause the light eruption without sunburn (as sunburn is mainly due to UV-B). UV-A, unlike UV-B, can penetrate window glass and is less well blocked by sunscreens. When in situations that are likely to provoke the rash, cover up as much as possible with densely woven clothing. Select broad-spectrum, water-resistant semi-opaque sun protection factor (SPF) 50+ sunscreens and apply before exposure and every two hours on skin that is not covered. […] Low-dose narrowband UV-B and other forms of phototherapy undertaken in late winter or early skin can reduce the incidence and severity of polymorphous light eruption. The course is 2 to 3 treatments per week for 4 to 6 weeks each year.

• #69 Polymorphous Light Eruption: Symptoms, Causes, Treatment | Qwark

  https://qwarkhealth.com/conditions/polymorphous-light-eruption

  Polymorphous Light Eruption (PMLE), also known as sun allergy, can be prevented by avoiding exposure to sunlight during its peak hours, which are between 10 am and 2 pm. […] Moreover, protective clothing and accessories, such as long-sleeved shirts, hats, and sunglasses, can also be used to prevent PMLE. […] Use of sunscreen with a high SPF value and broad-spectrum coverage can also reduce the risk of PMLE. […] Yes, wearing protective clothing that covers the arms, legs, and face can be effective in preventing PMLE. […] Avoiding exposure to UV rays is the most effective way to prevent PMLE. […] Sunscreen use should be implemented by first selecting a broad-spectrum sunscreen with an SPF value of at least 30.

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