Materiały źródłowe

• #1 Polymorphous light eruption – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/polymorphous-light-eruption/diagnosis-treatment/drc-20355872

  Treatment of polymorphous light eruption often isn’t needed because the rash usually goes away on its own within 10 days. If your symptoms are severe, your healthcare professional may prescribe anti-itch medicine (a corticosteroid cream or pill). […] Your healthcare professional may suggest phototherapy to prevent seasonal episodes of polymorphous light eruption if you have disabling symptoms. This exposes the skin to small doses of UVA or UVB light that helps your skin be less sensitive to light. It mimics the increased exposure you would experience during a summer.

• #1 Polymorphous Light Eruption Treatment & Management: Medical Care, Prevention

  https://emedicine.medscape.com/article/1119686-treatment

  Photoavoidance (eg, avoiding sunlight, wearing protective clothing, using sunscreen) remains a key factor in the care of patients with polymorphous (polymorphic) light eruption (PMLE). Broad-spectrum sunscreens are recommended because sunscreens with high sun protection factor (SPF) values are not necessarily protective against ultraviolet (UV) A (UVA)-induced PMLE. […] Phototherapy with UVA1, narrowband UVB, psoralen plus UVA (PUVA), or broadband UVB can harden the skin against the development of PMLE. […] Several studies found PUVA to be superior to UVB, controlling the outbreaks in 90% of patients. […] Antioxidants have also been suggested for helping to prevent PMLE lesions. […] The use of topical antioxidants such as 0.25% alpha-glucosyl-rutin and 1% vitamin E along with a broad-spectrum highly UVA-protective sunscreen was found to be helpful in PMLE patients.

• #1 Polymorphic light eruption

  https://www.nhs.uk/conditions/polymorphic-light-eruption/

  There’s no cure for polymorphic light eruption, but using sunscreens and careful avoidance of the sun will help you manage the rash. […] Avoid the sun, particularly between 11am and 3pm when the sun’s rays are at their strongest, and wear protective clothing when outdoors (unless your doctor has advised you to try hardening your skin). […] You may be prescribed sunscreens to help prevent the rash developing. […] Use a sunscreen that is SPF 50 or above with a UVA rating of 4 or 5 stars. Apply sunscreen thickly and evenly around 15 to 30 minutes before going out into the sun. […] Reapply every 2 hours and straight after you’ve dried yourself off after swimming. […] A GP can prescribe corticosteroid (steroid) cream or ointment that’s only applied when the rash appears. […] It’s sometimes possible to increase the resistance of your skin to the sun.

• #1 Polymorphic light eruption (PMLE) — DermNet

  https://dermnetnz.org/topics/polymorphic-light-eruption

  What is the treatment for polymorphic light eruption? […] General measures […] – Broad-spectrum 50+ SPF UVA/UVB sunscreen […] – Sun protective clothing […] – Avoid sunlight, choose shaded areas if outdoors and sit away from windows […] Specific measures […] – Potent topical corticosteroids such as betamethasone dipropionate 0.05% or mometasone 0.1% ointment for the body and weaker topical corticosteroids for the face such as hydrocortisone 1% ointment. […] – Short courses of oral corticosteroids oral prednisolone 0.51mg/kg over 12 weeks during a flare, or during vacations when there is increased sun exposure. […] – Phototherapy UVB or UVA in early spring to induce hardening, may need topical or oral steroids first to prevent a flare. […] – Hydroxychloroquine 200mg daily or twice daily through spring and summer.

• #1 Polymorphous Light Eruption Treatment & Management: Medical Care, Prevention

  https://emedicine.medscape.com/article/1119686-treatment

  Some authorities believe that vitamin therapy is helpful in the treatment of PMLE. […] Topical corticosteroids are useful, as would be expected in many dermatoses associated with lymphocytic skin infiltrate. […] Systemic steroids may be needed to suppress acute flares or extensive generalized eruption. […] Antihistamines may help with pruritus. […] Antimalarials at low doses are sometimes helpful, especially in patients with a large papular variety of PMLE. […] Azathioprine was reported to be effective in two cases of recalcitrant severe disease at 0.8-2.5 mg/kg/day for 3 months. […] Other therapies (eg, cyclosporine) can be helpful, but further studies are needed to determine their benefits. […] Interest in the use of thalidomide for a number of dermatoses (eg, Behet syndrome, cutaneous lupus, porphyria cutanea tarda, and PMLE) has been reemerging. […] Polypodium leucotomos, a tropical fern extract, was found to be helpful in delaying PMLE symptoms. […] Afamelanotide may alleviate symptoms of PMLE by increasing the pigment in the skin, and it could be photoprotective for some patients.

• #1 Interventions for polymorphic light eruption

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6485352/

  PsoralenUVA (PUVA), narrowband (NBUVB) or broadband UVB (BBUVB) phototherapy is currently the mainstay of treatment for more severe PLE. […] Other antiinflammatory agents and immunomodulators that have been used include: azathioprine and cyclosporin; hydroxychloroquine; betacarotene; nicotinamide; omega3 polyunsaturated fatty acids; topical antioxidants; E. coli filtrate; thalidomide. […] Sun protection, corticosteroids and desensitisation phototherapy appear to be the current mainstay of treatment, with immunomodulator agents as secondline treatment.

• #1 Successful short desensitization treatment protocol with narrowband UVB phototherapy (TL-01) in polymorphic light eruption | Actas Dermo-Sifiliográficas

  https://www.actasdermo.org/en-successful-short-desensitization-treatment-protocol-articulo-S1578219017302986

  Successful short desensitization treatment protocol with narrowband UVB phototherapy (TL-01) in polymorphic light eruption […] To describe and evaluate the efficacy of a short desensitization protocol, based on a one-month-treatment, administered twice a week with narrow band UVB in subjects with severe polymorphic light eruption (PLE). […] The effect of hardening was maintained in the vast majority of subjects, obtaining a good benefit with no PLE episodes during all the summer. We demonstrate that our standard protocol is effective, and produces a successful outcome for the majority of PLE subjects. […] In this study we describe a short desensitization protocol based on a four-week treatment with narrow band UVB (NB-UVB, TL-01, 3112nm bandwidth) that may guide other physicians intending to use these forms of therapy.

• #1 Polymorphous Light Eruption Symptoms, Causes, and Treatment

  https://www.healthline.com/health/polymorphous-light-eruption

  PMLE is generally treatable with both home remedies and medical interventions. […] Gradual hardening is one form of treating PMLE. This can be done through careful and measured exposure to sunlight, or it can be achieved through the use of phototherapy. […] Dermatologists can expose you to UV light a few times per week before the sun becomes strong in the spring to help avoid severe PMLE. This should only be done by a professional. This typically has to be repeated after every winter. […] After the rash has already appeared, a doctor may prescribe corticosteroids to help alleviate itchiness or burning. […] Other medications that might be used to treat PMLE include: oral steroids, hydroxychloroquine, Polypodium leucotomos extract, lycopene, nicotinamide, beta carotene, astaxanthin, canthaxanthin.

• #1 Polymorphic light eruption

  https://www.nhs.uk/conditions/polymorphic-light-eruption/

  This involves visiting a hospital dermatology department 3 times a week for 4 to 6 weeks in the spring. […] A GP or dermatologist may advise you to try increasing the resistance of your skin at home. […] This is known as „hardening” and involves going outside for short periods in the spring to build up your resistance. […] People with polymorphic light eruption are at greater risk of vitamin D deficiency, as a certain amount of sun exposure is needed to make your own vitamin D. […] A GP can advise whether you need treatment with vitamin D supplements.

• #1 Polymorphous Light Eruptions Treated With Roflumilast 0.3% Cream: A Case Report – JDDonline – Journal of Drugs in Dermatology

  https://jddonline.com/articles/polymorphous-light-eruptions-treated-with-roflumilast-03-cream-case-report-S1545961624P8398X/

  Polymorphous light eruption (PMLE) is a photosensitivity disorder that presents as, erythematous papulovesicles in sun-exposed regions of the skin that can progress to large plaques and bullae. Typical treatments include sun protection, corticosteroids, systemic anti-malarial and desensitizing phototherapy. However, these treatments can be ineffective and laborious, especially desensitization phototherapy. […] We present a case of a patient with PMLE who experienced resolution after treatment with roflumilast 0.3% cream. […] She experienced significant improvement in symptoms and rash clearance after using roflumilast 0.3% cream once daily for 2 weeks.

• #1 Polymorphous light eruption | Health Library | Memorial Health System

  https://www.mhsystem.org/health-library/con-20257399/

  Polymorphous light eruption usually goes away on its own without scarring within 10 days. People with severe or persistent rashes may need medication. […] Treatment of polymorphous light eruption usually isn’t needed because the rash usually goes away on its own within 10 days. If your symptoms are severe, your health care provider may prescribe anti-itch medicine (a corticosteroid cream or pill). […] Your health care provider may suggest phototherapy to prevent seasonal episodes of polymorphous light eruption if you have disabling symptoms. This exposes the skin to small doses of UVA or UVB light that helps your skin be less sensitive to light. It mimics the increased exposure you would experience during a summer. […] Self-care measures that may help ease signs and symptoms include: Applying anti-itch cream. Try a nonprescription anti-itch cream, which may include products containing at least 1% hydrocortisone. Taking antihistamines. If itching is a problem, oral antihistamines may help. Using cold compresses. Apply a towel dampened with cool tap water to the affected skin. Or take a cool bath. Leaving blisters alone. To speed healing and avoid infection, leave blisters intact. If needed, you can lightly cover blisters with gauze. Taking a pain reliever. A nonprescription pain medication may help reduce inflammation and pain. Protect the rash from further sun exposure. When you go outside, cover the area where the rash developed.

• #1 Top 10 Home Remedies for PMLE Rash – Natural Treatment

  https://www.iafaforallergy.com/blog/home-remedies-for-pmle-rash/

  Polymorphous light eruption (PMLE) rashes are commonly known as sun allergy or sun poisoning. These are irritating and itchy red bumps on the skin caused due to exposure to harsh UV or sun rays. […] Protect your skin from sunlight exposure by wearing protective clothing, such as long sleeves, wide-brimmed hats, and sunglasses. Seek shade during peak sunlight hours. Applying sunscreen is a must when you step out because getting exposed to UV rays or sun rays may damage the skin and lead to skin irritation. […] Apply pure aloe vera gel to the affected areas to soothe and moisturize the skin. Aloe vera has anti-inflammatory and soothing properties that may help reduce redness and irritation and regular application of Aloe Vera improves overall skin health. […] Apply organic, cold-pressed coconut oil to the rash. Coconut oil has moisturizing and anti-inflammatory properties that can help soothe the skin.

• #1 Polymorphous light eruption – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/polymorphous-light-eruption/symptoms-causes/syc-20355868

  Polymorphous light eruption usually goes away on its own without scarring within 10 days. People with severe or persistent rashes may need medicine. […] Polymorphous light eruption rashes look similar to rashes caused by other diseases, some of which are serious. So it’s important to get a prompt diagnosis and treatment. […] Seek immediate medical care if your rash: Is widespread. Is painful. Comes with a fever. […] The exact cause of polymorphous light eruption isn’t understood. The rash appears in people who have developed sensitivity to sunlight, especially ultraviolet (UV) radiation from the sun or other sources, such as tanning beds. This is called photosensitivity. It leads to immune system activity that causes a rash. […] With polymorphous light eruption, sensitivity to sunlight lessens with repeated exposure. Features of polymorphous light eruption are somewhat predictable: An episode is most likely to occur after the first one or two times of sun exposure after a long period of no exposure, such as in spring or early summer. […] Episodes are less likely to happen as the summer progresses. After the first episode, it’s likely to happen each year. Some people gradually become less sensitive over several years and eventually no longer experience the yearly rash.

• #1

  https://zana.com/a/polymorphic-light-eruption-treated.7175

  There’s no cure for polymorphic light eruption, but careful avoidance of the sun and using sunscreens will help you manage the rash. […] You may be prescribed sunscreens, which may prevent the rash developing. […] Your GP can prescribe corticosteroid (steroid) cream or ointment, to be applied only when the rash appears. […] Sometimes you can increase the resistance of your skin to the sun. This involves visiting a hospital department three times a week for four to six weeks in the spring. […] You may be able to increase the resistance of your skin at home, which is known as „hardening”. […] People with polymorphic light eruption are at greater risk of vitamin D deficiency, as a certain amount of sun exposure is needed to make your own vitamin D.

• #1 Polymorphic light eruption (PLE) – British Skin Foundation

  https://knowyourskin.britishskinfoundation.org.uk/condition/polymorphic-light-eruption/

  A few people with extensive PLE may still have problems despite the measures listed above. Some tablets (such as hydroxychloroquine), which are usually prescribed for malaria, may be helpful in some cases. A short course of oral steroids can be considered at times, e.g. to cover a summer holiday. If very resistant to the treatments mentioned above, other oral non-steroidal agents like azathioprine can also be used. Using oral or topical antioxidants as well as oral nicotinamide prior or after the first sun exposure has shown to prevent PLE. Topical antioxidants (such as Vitamin E, as a combination with UVA sunscreen) and topical corticosteroid also help decrease itch. […] No, treatment will not be able to get rid of PLE; however, many people do not have a recurrence if they avoid exposure to the sun and use an effective sunscreen. The tendency to get PLE may go away by itself after a few years as the skin becomes more adapted to sunlight. The aim of the treatment is both to minimize the severity of the symptoms and prevent the disease from occurring.

• #1 Polymorphic light eruption (PMLE) — DermNet

  https://dermnetnz.org/topics/polymorphic-light-eruption

  – Topical calcipotriol may be useful as prophylaxis prior to sun exposure. […] – Afamelanotide […] – Nicotinamide typically given 24 weeks prior to usual time of year PMLE is provoked; 13 grams per day (in divided doses) have been used. […] – If severe, systemic immunosuppressants such as azathioprine or ciclosporin (cyclosporine) […] […] […] PMLE may be lifelong although 60% of people see improvement or resolution over 15 years and 75% of people in 30 years.

• #1

  https://journals.lww.com/idoj/fulltext/2021/12020/polymorphous_light_eruption__an_indian_scenario.1.aspx

  Polymorphous light eruption (PMLE) is the most common, idiopathic, acquired photodermatosis, characterized by abnormal, recurrent, and delayed reaction to sunlight. […] The management of PMLE includes both preventive measures and medical management. Topical sunscreens, topical steroids, hydroxychloroquine and antioxidants play a very important role. […] Treatment should be based on the age, sex, occupation, and site of involvement. In Indian context, economic conditions also should be considered. The management designed individually to suit the patients can be successful in the treatment and prevention of the disease. […] Sun avoidance is the only definitive way of preventing PMLE. But this is not possible in a largely agricultural country like India. Sun protection may be a useful alternative. Sun protection should be advised as a preventive measure during summer months with sun avoidance between 11.00 am and 3.00 pm accompanied by regular application of sunscreens.

• #2 Polymorphous Light Eruption (PMLE): Symptoms, Causes & Treatments

  https://my.clevelandclinic.org/health/diseases/17888-polymorphous-light-eruption-pmle

  PMLE typically resolves on its own without treatment. […] People living with PMLE should avoid exposure to sunlight, especially between 11 a.m. and 3 p.m., when UV rays are strongest. Using high SPF, broad-spectrum sunscreen, and wearing protective clothing helps minimize UV light exposure. […] Some people benefit from phototherapy as a way to harden their skin. Repeated, controlled exposure to natural or artificial UV light helps desensitize skin and prevents future rashes. […] If you’re going someplace sunny on vacation, your healthcare provider may prescribe an oral corticosteroid like prednisone to reduce your chances of getting a rash. […] For severe rashes, your provider may prescribe: Antihistamines, Hydroxychloroquine, Immunosuppressants, Topical corticosteroids or tacrolimus.

• #2 Polymorphic light eruption

  https://www.nhs.uk/conditions/polymorphic-light-eruption/

  There’s no cure for polymorphic light eruption, but using sunscreens and careful avoidance of the sun will help you manage the rash. […] Avoid the sun, particularly between 11am and 3pm when the sun’s rays are at their strongest, and wear protective clothing when outdoors (unless your doctor has advised you to try hardening your skin). […] You may be prescribed sunscreens to help prevent the rash developing. […] Use a sunscreen that is SPF 50 or above with a UVA rating of 4 or 5 stars. Apply sunscreen thickly and evenly around 15 to 30 minutes before going out into the sun. […] Reapply every 2 hours and straight after you’ve dried yourself off after swimming. […] A GP can prescribe corticosteroid (steroid) cream or ointment that’s only applied when the rash appears. […] It’s sometimes possible to increase the resistance of your skin to the sun.

• #2 Polymorphous Light Eruption Treatment & Management: Medical Care, Prevention

  https://emedicine.medscape.com/article/1119686-treatment

  Photoavoidance (eg, avoiding sunlight, wearing protective clothing, using sunscreen) remains a key factor in the care of patients with polymorphous (polymorphic) light eruption (PMLE). Broad-spectrum sunscreens are recommended because sunscreens with high sun protection factor (SPF) values are not necessarily protective against ultraviolet (UV) A (UVA)-induced PMLE. […] Phototherapy with UVA1, narrowband UVB, psoralen plus UVA (PUVA), or broadband UVB can harden the skin against the development of PMLE. […] Several studies found PUVA to be superior to UVB, controlling the outbreaks in 90% of patients. […] Antioxidants have also been suggested for helping to prevent PMLE lesions. […] The use of topical antioxidants such as 0.25% alpha-glucosyl-rutin and 1% vitamin E along with a broad-spectrum highly UVA-protective sunscreen was found to be helpful in PMLE patients.

• #2 Polymorphous light eruption Information | Mount Sinai – New York

  https://www.mountsinai.org/health-library/diseases-conditions/polymorphous-light-eruption

  Polymorphous light eruption (PMLE) is a common skin reaction in people who are sensitive to sunlight (ultraviolet light). […] Steroid creams or ointments containing vitamin D may be prescribed by your provider. They are used 2 or 3 times a day at the start of the eruption. Steroid or other types of pills may be used for more severe cases. […] Phototherapy may also be prescribed. Phototherapy is a medical treatment in which your skin is carefully exposed to ultraviolet light. This may help your skin become used to (sensitized to) the sun.

• #2 Successful short desensitization treatment protocol with narrowband UVB phototherapy (TL-01) in polymorphic light eruption | Actas Dermo-Sifiliográficas

  https://www.actasdermo.org/en-successful-short-desensitization-treatment-protocol-articulo-S1578219017302986

  The standard treatment protocol for narrowband UVB (TL-01) is shown in Table 1. The starting dose was 0.15J/cm2. This was followed by a 20% incremental dosage, twice a week, during four weeks. […] The evaluation of response was performed both after finishing the desensitization treatment and at the beginning of autumn. The effect of hardening was sustained during the follow up after 21 desensitization treatment courses, as subjects reported a complete remission of symptoms during all the sunny Spanish summer. […] The protocol that we propose is shorter than those currently applied, being favourable both for the patient and the physician. Thereby, treatment adherence will probably increase and the cost of the treatment might be reduced.

• #2 Polymorphic light eruption (PLE) – British Skin Foundation

  https://knowyourskin.britishskinfoundation.org.uk/condition/polymorphic-light-eruption/

  When the rash comes up, topical or oral corticosteroids, as well as oral antihistamine may help to reduce itching. […] Mild PLE may be controlled by following the top sun safety tips listed below in the Self care (What can I do?) section below. […] If very troublesome, desensitisation treatment may be considered. Desensitisation is a way of raising the skins resistance by treating it with increasing doses of ultraviolet light in a special phototherapy cubicle. The treatment is given in the early spring so that the skin is ready to cope with the summer sun. The effect of desensitisation treatment wears off in the winter, so it should be repeated every spring. […] Gradual exposure to sunlight in the springtime may help to reduce the severity of the rash when the summer comes in individuals who have a mild PLE.

• #2 Polymorphic light eruption – BAD Patient Hub

  https://www.skinhealthinfo.org.uk/condition/polymorphic-light-eruption/

  This leaflet has been written to help you understand more about polymorphic light eruption (PLE). […] Please note that some of the treatment options in this leaflet may not be available on the NHS. […] No, treatment will not be able to get rid of PLE; however, many people do not have a recurrence if they avoid exposure to the sun and use an effective sunscreen. The aim of the treatment is both to minimize the severity of the symptoms and prevent the disease from occurring. […] When the rash comes up, topical or oral corticosteroids, as well as oral antihistamine may help to reduce itching. […] If very troublesome, desensitisation treatment may be considered. Desensitisation is a way of raising the skins resistance by treating it with increasing doses of ultraviolet light in a special phototherapy cubicle.

• #2 Polymorphous Light Eruption Treatment & Management: Medical Care, Prevention

  https://emedicine.medscape.com/article/1119686-treatment

  Some authorities believe that vitamin therapy is helpful in the treatment of PMLE. […] Topical corticosteroids are useful, as would be expected in many dermatoses associated with lymphocytic skin infiltrate. […] Systemic steroids may be needed to suppress acute flares or extensive generalized eruption. […] Antihistamines may help with pruritus. […] Antimalarials at low doses are sometimes helpful, especially in patients with a large papular variety of PMLE. […] Azathioprine was reported to be effective in two cases of recalcitrant severe disease at 0.8-2.5 mg/kg/day for 3 months. […] Other therapies (eg, cyclosporine) can be helpful, but further studies are needed to determine their benefits. […] Interest in the use of thalidomide for a number of dermatoses (eg, Behet syndrome, cutaneous lupus, porphyria cutanea tarda, and PMLE) has been reemerging. […] Polypodium leucotomos, a tropical fern extract, was found to be helpful in delaying PMLE symptoms. […] Afamelanotide may alleviate symptoms of PMLE by increasing the pigment in the skin, and it could be photoprotective for some patients.

• #2 Polymorphous light eruption: Pictures and treatments

  https://www.medicalnewstoday.com/articles/polymorphous-light-eruption

  There is no cure for PLE, but the condition often gets better on its own in a few days. If the symptoms do not improve or are severe, a doctor may prescribe: […] A mild to moderate topical corticosteroid cream may help reduce inflammation. Another option is topical calcipotriol, which is a vitamin D derivative people can use before sun exposure. […] This involves controlled exposure to sunlight or artificial UV light under the direction of a dermatologist. Repeated and gradual exposure to the sun may reduce sensitivity. Doctors may use UVA or UVB light. […] This stronger form of steroid medication reduces itching and speeds healing in severe cases of PLE. […] This medication stimulates the production of a type of melanin in the skin, resulting in a tan. This can help protect the skin from UV light and reduce sensitivity to it.

• #2 Polymorphic Light Eruption (PMLE): Causes and Treatment

  https://patient.info/doctor/polymorphic-light-eruption-pro

  Severe PMLE may be treated with: […] Prophylactic light therapy (before sun exposure – eg, in early spring), which may help. This is known as 'photohardening’ and aims to induce sunlight tolerance, using controlled exposure. This may use: UVB. UVA/UVB. Psoralen combined with UVA (PUVA) treatment. […] Recently, light-emitting diode (LED) treatment has also been suggested. […] Beta carotene and hydroxychloroquine can both improve tolerance to the sun. […] Topical vitamin D analogues have been used with promising results. […] Immunomodulators (eg, azathioprine or thalidomide) have been used in the past to treat photodermatoses; however, the risk of adverse effects has meant that their use has declined as other treatments have become available.

• #2

  https://sunsaferx.com/blogs/health-wellness/polymorphous-light-eruption-treatment-prevention?srsltid=AfmBOoqS6Btun_UGjYTSu9i2mmcnTYbyhHhRE1LrjEG_V-mefF-1Bdh4

  Polymorphous light eruption usually resolves on its own within a week or two. Since rashes will normally heal if sun exposure is avoided, further sun rash treatment may not be necessary. […] However, medications or other treatments may be needed to treat persistent cases. […] Self-care measures that may decrease the symptoms of PLE, such as itching, include: Using cold compresses: apply a towel dampened with cool water to the affected skin, or take a bath in cool water. […] Taking pain relievers and anti-inflammatories: Over-the-counter medication such as ibuprofen (Motrin, Advil), acetaminophen (Tylenol), and naproxen (Aleve) may help reduce inflammation, redness, itchiness, and pain. […] For more severe or troublesome PLE, your doctor may consider prescribing: Stronger topical corticosteroids than are available over-the-counter, Oral corticosteroids, Hydroxychloroquine: This is a medication usually used to treat malaria, but is also used to reduce inflammation in the treatment of conditions such as rheumatoid arthritis and lupus.

• #2 Top 10 Home Remedies for PMLE Rash – Natural Treatment

  https://www.iafaforallergy.com/blog/home-remedies-for-pmle-rash/

  Brew green tea, let it cool, and apply it as a compress to the affected areas using a clean cloth or a cotton swab. Green tea contains antioxidants and anti-inflammatory compounds and aids in the Natural Treatment of PMLE Rash and it may provide relief from itching and inflammation. […] Apply witch hazel extract to the affected areas using a cotton ball. Witch hazel has astringent and anti-inflammatory properties that may help reduce inflammation and soothe the skin and helps in quick healing of PMLE rashes. […] Chamomile tea has good anti-inflammatory properties and is said to be of great help in treating allergies, so consuming chamomile tea can reduce inflammation, boosts immunity and treats rashes. […] Apply vitamin E oil directly to the rash to moisturize the skin and promote healing. Vitamin E has antioxidant properties that can help reduce inflammation.

• #2 How to Recognize and Treat a Sun Rash

  https://www.verywellhealth.com/sun-rash-8742965

  In some instances, phototherapy or „skin hardening,” which involves controlled exposure to UV light in the springtime, can help acclimate the skin and prevent sun rashes during summertime. […] While most sun rash symptoms resolve on their own and can be successfully treated with home remedies, contact a healthcare provider if a sun rash shows signs of infection or includes symptoms associated with a sun poisoning rash like fever, chills, nausea, vomiting, or dizziness.

• #3 Polymorphous light eruption

  https://ask-ahd.ahdubai.com/con-20257399

  Self-care measures that may help ease your signs and symptoms include: Applying anti-itch cream. Try an over-the-counter (nonprescription) anti-itch cream, which may include products containing at least 1 percent hydrocortisone. […] To lessen the likelihood of recurring episodes of polymorphous light eruption, take the following precautions: Avoid the sun between 10 a.m. and 2 p.m. […] Use sunscreen. Fifteen to 30 minutes before going outdoors, apply a broad-spectrum sunscreen, one that provides protection from both UVA and UVB light. Use a sunscreen with a sun protection factor (SPF) of at least 30. […] Consider wearing clothing designed to provide sun protection. Look for clothes labeled with an ultraviolet protection factor (UPF) of 40 to 50.

• #3 FloridaHealthFinder | Polymorphous light eruption | Health Encyclopedia | FloridaHealthFinder

  https://quality.healthfinder.fl.gov/health-encyclopedia/HIE/1/001477

  Steroid creams or ointments containing vitamin D may be prescribed by your provider. They are used 2 or 3 times a day at the start of the eruption. Steroid or other types of pills may be used for more severe cases. […] Phototherapy may also be prescribed. Phototherapy is a medical treatment in which your skin is carefully exposed to ultraviolet light. This may help your skin become used to (sensitized to) the sun.

• #3

  https://journals.lww.com/idoj/fulltext/2021/12020/polymorphous_light_eruption__an_indian_scenario.1.aspx

  Hydroxychloroquine 400 mg daily for the first month followed by 200 mg daily for 12 weeks has shown to have a mild benefit in PMLE with a reduction in the severity of the rash. […] Systemic immunosuppressants like azathioprine may be recommended in PMLE in the following situations: extreme sun sensitivity, intolerance to phototherapy, patients in whom sunscreens are ineffective.

• #3

  https://link.springer.com/article/10.1007/BF00417337

  This study was designed in order to prove on a large-scale basis the efficacy of oral photochemotherapy (PUVA) in the prevention of polymorphous light eruption (PLE), to work out indication criteria for PUVA treatment of this disease, and to establish a simple method based on anamnestic data to differentiate UVA from UVB induced PLE. […] PUVA thus seems the treatment of choice only in UVA-mediated PLE, the action spectrum of the disease at least in most cases being easily discovered from certain anamnestic data.

• #3 Polymorphic light eruption (PMLE) — DermNet

  https://dermnetnz.org/topics/polymorphic-light-eruption

  – Topical calcipotriol may be useful as prophylaxis prior to sun exposure. […] – Afamelanotide […] – Nicotinamide typically given 24 weeks prior to usual time of year PMLE is provoked; 13 grams per day (in divided doses) have been used. […] – If severe, systemic immunosuppressants such as azathioprine or ciclosporin (cyclosporine) […] […] […] PMLE may be lifelong although 60% of people see improvement or resolution over 15 years and 75% of people in 30 years.

• #3 Top 10 Home Remedies for PMLE Rash – Natural Treatment

  https://www.iafaforallergy.com/blog/home-remedies-for-pmle-rash/

  Cold compresses help in the Natural Treatment of PMLE Rash. Apply cold compresses to the affected areas to help alleviate itching and reduce inflammation. […] Drink plenty of water to keep your body hydrated. Staying hydrated can help improve overall skin health and reduce dryness or flakiness associated with PMLE. […] Following the natural home remedies mentioned above can give you relief from the itching and ending sensations of rashes.

• #4 Polymorphic light eruption (PMLE) — DermNet

  https://dermnetnz.org/topics/polymorphic-light-eruption

  – Topical calcipotriol may be useful as prophylaxis prior to sun exposure. […] – Afamelanotide […] – Nicotinamide typically given 24 weeks prior to usual time of year PMLE is provoked; 13 grams per day (in divided doses) have been used. […] – If severe, systemic immunosuppressants such as azathioprine or ciclosporin (cyclosporine) […] […] […] PMLE may be lifelong although 60% of people see improvement or resolution over 15 years and 75% of people in 30 years.

• #4 Common Vitamins and Supplements to Treat polymorphous-light-eruption-pmle

  https://www.webmd.com/vitamins/condition-2329/polymorphous-light-eruption-pmle

  Considering taking supplements to treat polymorphous light eruption pmle? Below is a list of common natural remedies used to treat or reduce the symptoms of polymorphous light eruption pmle. […] 5 results found to treat polymorphous light eruption pmle […] Treatment […] Effectiveness […] Reviews […] lycopene Insufficient Evidence Reviews […] canthaxanthin Insufficient Evidence Reviews […] beta-carotene Insufficient Evidence Reviews […] polypodium leucotomos Insufficient Evidence Reviews […] lactobacillus acidophilus Insufficient Evidence Reviews.

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