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• #1 Polymorphic light eruption (PMLE) — DermNet

  https://dermnetnz.org/topics/polymorphic-light-eruption

  Polymorphic light eruption (PMLE) is a seasonal, acquired, idiopathic photodermatosis occurring in spring and early summer. […] Patients with PMLE can develop a tolerance during summer months. […] PMLE is a delayed hypersensitivity reaction in the skin to unknown endogenous cutaneous photo-induced antigens. […] The following factors must be considered when determining pathogenesis and when implementing protective measures: It is primarily caused by either UVA (7590%) or UVB light alone or UVA and UVB light concurrently. […] PMLE persists for several days and can worsen if the affected skin is exposed to further sunlight before resolution of the previous eruption. It resolves without scarring. […] There is a phenomenon called the skin hardening effect where chronic exposure to sunlight leads to skin changes including increased melanin and thickening of the stratum corneum.

• #1 Polymorphous light eruption – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/polymorphous-light-eruption/diagnosis-treatment/drc-20355872

  Your healthcare professional can probably make a diagnosis of polymorphous light eruption based on a physical exam and your answers to questions. […] Treatment of polymorphous light eruption often isn’t needed because the rash usually goes away on its own within 10 days. If your symptoms are severe, your healthcare professional may prescribe anti-itch medicine (a corticosteroid cream or pill). […] Your healthcare professional may suggest phototherapy to prevent seasonal episodes of polymorphous light eruption if you have disabling symptoms. This exposes the skin to small doses of UVA or UVB light that helps your skin be less sensitive to light. […] To lessen the likelihood of recurring episodes of polymorphous light eruption, take the following precautions: […] Avoid sun exposure whenever possible. If you can’t avoid the sun, use a broad-spectrum sunscreen with an SPF of at least 30 in areas that cannot be protected by clothing. Apply it generously 15 minutes before sun exposure. Reapply it every two hours or more often if you’re swimming or sweating. This won’t totally protect you from a reaction, as ultraviolet A may penetrate through most sunscreens.

• #1

  https://www.ijord.com/index.php/ijord/article/view/92

  Polymorphic light eruption (PMLE) is an acquired photodermatosis characterized by a polymorphic eruption ranging from papulovesicular lesions to large plaques. […] The present study was conducted to study the clinical pattern and to assess the epidemiological aspects of polymorphic light eruption. […] Majority of the cases in our study were in the age group of 21 – 30 years (36%). […] It was more common in females (82%) when compared with males (18%). […] The commonest form was the papular type (46%) and the second most common type was plaque type (17%). […] The prevalence of PMLE was 1.34% in our study population. […] Pruritus was the presenting complaint in most of the cases and the rash was mainly seen in areas exposed to sunlight.

• #1 Polymorphic Light Eruption | PLE Treatment | OneWelbeck

  https://onewelbeck.com/conditions/polymorphic-light-eruption/

  A dermatologist can usually diagnose PLE with a simple history and skin examination. […] Phototesting may also be done to exclude rarer types of sun sensitivity. […] Symptoms are usually apparent within a few hours but can appear up to 2 to 3 days after exposure to sunlight. […] Symptoms usually last for less than a week and resolve as normal skin. […] The appearance of a PLE rash varies from person to person. […] For some patients, PLE can ruin enjoyment of sunny days in the UK and holidays abroad in warm climates. […] Theres no cure for PLE, but there are various measures that can be taken to help minimize the severity of the rash and also prevent it from occurring: Regular application of SPF 50, Covering the areas most susceptible to rashes (chest, shoulders, upper arms, thighs) with clothing when in the sun, and wearing a hat, Being careful with sun exposure, avoiding the most intense times of the day if possible. […] In some cases, corticosteroid creams or ointments, as well as oral antihistamines, may be recommended by your dermatologist to use when the rash appears. […] If your rash is very severe, you should seek the advice of one of our specialists as you may be suffering from a more serious condition.

• #1 Polymorphous light eruption – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/polymorphous-light-eruption/symptoms-causes/syc-20355868

  Polymorphous light eruption usually goes away on its own without scarring within 10 days. People with severe or persistent rashes may need medicine. […] Polymorphous light eruption rashes look similar to rashes caused by other diseases, some of which are serious. So it’s important to get a prompt diagnosis and treatment. […] Seek immediate medical care if your rash: Is widespread. Is painful. Comes with a fever. […] The exact cause of polymorphous light eruption isn’t understood. The rash appears in people who have developed sensitivity to sunlight, especially ultraviolet (UV) radiation from the sun or other sources, such as tanning beds. This is called photosensitivity. It leads to immune system activity that causes a rash. […] With polymorphous light eruption, sensitivity to sunlight lessens with repeated exposure. Features of polymorphous light eruption are somewhat predictable: An episode is most likely to occur after the first one or two times of sun exposure after a long period of no exposure, such as in spring or early summer. Episodes are less likely to happen as the summer progresses. After the first episode, it’s likely to happen each year. Some people gradually become less sensitive over several years and eventually no longer experience the yearly rash. […] Anyone can develop polymorphous light eruption, but several things can increase your risk of the condition: Being female. Having skin that sunburns easily. Living in northern regions. Having a family history of the condition.

• #1

  https://www.nursingcenter.com/journalarticle?Article_ID=5705365&Journal_ID=849729&Issue_ID=5705176

  ABSTRACT: While there are a number of skin rashes associated with photosensitivity, only one produces a distinctive rash with fixed urticaria, macular erythema, and papulovesicles forming small papules and plaques. This polymorphous light eruption requires aggressive broad spectrum UV protection, topical steroids for pruritus, and paradoxically sometimes UV light treatment to „harden” the skin making skin more resistant to rashing when exposed to the sun. […] Skin care recommendations: The patient was instructed to use a broad-spectrum (UVA/UVB blocking) sunscreen with SPF 30 or greater when exposed to the sun, especially in the first exposures in the springtime. […] PMLE is a common immunologically mediated photodermatosis that occurs in temperate climates. The variable appearance of pruritic skin lesions occurs most commonly in the spring or early summer on sun-exposed areas (Gruber-Wackernagel et al., 2014). Making this clinical diagnosis and recommending broad-spectrum UV avoidance and protection will most often lead to prompt resolution without further treatment or diagnostic testing (Bissonnette et al., 2012).

• #1 Polymorphic Light Eruption – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK430886/

  Polymorphic light eruption is the most common form of immunologically mediated photosensitivity dermatoses. Exposure to sunlight in spring or summer results in an irritable rash that resolves within a few days, providing further exposure is avoided. […] Management requires determining what provokes the eruption and then attempting to minimize this, while at the same time gradually increasing exposure to induce hardening. […] These healthcare professionals should educate the patients on prevention which includes wearing appropriate garments when going outside and use ample sunscreen frequently.

• #1 Polymorphous light eruption – Augusta HealthSearchClose SearchSearch IconSearch IconClose Search IconMobile Menu IconMobile Menu Close IconInstagramFacebookTwitterYoutube

  https://www.augustahealth.com/disease/polymorphous-light-eruption/

  Self-care measures that may help ease your signs and symptoms include: Applying anti-itch cream. Try an over-the-counter (nonprescription) anti-itch cream, which may include products containing at least 1 percent hydrocortisone. Taking antihistamines. If itching is a problem, oral antihistamines may help. Using cold compresses. Apply a towel dampened with cool tap water to the affected skin, or take a cool bath. Leaving blisters alone. To speed healing and avoid infection, leave blisters intact. If needed, you can lightly cover blisters with gauze. Taking a pain reliever. An over-the-counter pain medication may help reduce redness or pain. These include ibuprofen (Advil, Motrin IB, others), acetaminophen (Tylenol, others) and naproxen sodium (Aleve, others). […] To lessen the likelihood of recurring episodes of polymorphous light eruption, take the following precautions: Avoid the sun between 10 a.m. and 2 p.m. Because the sun’s rays are most intense during this time, try to schedule outdoor activities for other times of the day. Use sunscreen. Fifteen to 30 minutes before going outdoors, apply a broad-spectrum sunscreen, one that provides protection from both UVA and UVB light. Use a sunscreen with a sun protection factor (SPF) of at least 30. Apply sunscreen generously, and reapply every two hours — or more often if you’re swimming or perspiring. If you’re using a spray sunscreen, be sure to cover the entire area completely. Cover up. For protection from the sun, wear tightly woven clothing that covers your arms and legs and a broad-brimmed hat, which provides more protection than does a baseball cap or golf visor. Consider wearing clothing designed to provide sun protection. Look for clothes labeled with an ultraviolet protection factor (UPF) of 40 to 50. Follow care instructions on the label of UV-blocking clothes to maintain their protective feature.

• #1 Polymorphous Light Eruption Treatment & Management: Medical Care, Prevention

  https://emedicine.medscape.com/article/1119686-treatment

  Systemic steroids may be needed to suppress acute flares or extensive generalized eruption. […] Antihistamines may help with pruritus. […] Antimalarials at low doses are sometimes helpful, especially in patients with a large papular variety of PMLE. […] Polypodium leucotomos, a tropical fern extract, was found to be helpful in delaying PMLE symptoms. […] Afamelanotide may alleviate symptoms of PMLE by increasing the pigment in the skin, and it could be photoprotective for some patients.

• #1 Polymorphous light eruption | UM Health-Sparrow

  https://www.uofmhealthsparrow.org/departments-conditions/conditions/polymorphous-light-eruption

  Polymorphous light eruption usually goes away on its own without scarring within 10 days. People with severe or persistent rashes may need medicine. […] Treatment of polymorphous light eruption often isn’t needed because the rash usually goes away on its own within 10 days. If your symptoms are severe, your healthcare professional may prescribe anti-itch medicine (a corticosteroid cream or pill). […] Your healthcare professional may suggest phototherapy to prevent seasonal episodes of polymorphous light eruption if you have disabling symptoms. This exposes the skin to small doses of UVA or UVB light that helps your skin be less sensitive to light. It mimics the increased exposure you would experience during a summer. […] Try these self-care measures to help ease your symptoms: Apply anti-itch cream. Try a nonprescription anti-itch cream, which may include products containing at least 1% hydrocortisone. […] Protect the rash from further sun exposure. When you go outside, cover the area where the rash developed.

• #1 Dermatology – Polymorphic Light Eruption :: Northern Care Alliance

  https://www.northerncarealliance.nhs.uk/patient-information/patient-leaflets/dermatology-polymorphic-light-eruption?q=%2Fpatient-information%2Fpatient-leaflets%2Fdermatology-polymorphic-light-eruption

  Use a sunscreen that is SPF 30 or above (high UVB protection) and also has high UVA protection. Remember to re-apply the sunscreen evenly and often […] Learn how much sunlight your skin can tolerate and keep within that limit […] Make sure you introduce your skin to sunlight gradually in the spring. […] You will be provided with sunscreens on prescription, and these will help prevent the rash developing. Sunscreen should be applied as thickly and evenly as possible and re-applied often. […] Your doctor may prescribe corticosteroid creams or ointments to put on your skin in the evening if the rash appears. Steroid creams can be strong and should only be applied sparingly and while the rash is there. You should stop applying steroid cream when the rash has gone. […] Sometimes the resistance of your skin to the effects of the sun can be increased. This is done in a hospital department and will involve visiting the hospital three times a week for about 5 weeks in the spring.

• #1 Polymorphous light eruption | Beacon Health System

  https://www.beaconhealthsystem.org/library/diseases-and-conditions/polymorphous-light-eruption?content_id=CON-20257399

  To lessen the likelihood of recurring episodes of polymorphous light eruption, take the following precautions: Avoid the sun between 10 a.m. and 2 p.m. Because the sun’s rays are most intense during this time, try to schedule outdoor activities for other times of the day. Use sunscreen. Fifteen minutes before going outdoors, apply a broad-spectrum sunscreen, one that provides protection from both UVA and UVB light. Use a sunscreen with a sun protection factor (SPF) of at least 30. Apply sunscreen generously, and reapply every two hours or more often if you’re swimming or perspiring. If you’re using a spray sunscreen, be sure to cover the entire area completely. Cover up. For protection from the sun, wear tightly woven clothing that covers your arms and legs. Consider wearing a broad-brimmed hat, which provides more protection than does a cap or visor. Consider wearing clothing designed to provide sun protection. Look for clothes labeled with an ultraviolet protection factor (UPF) of 40 to 50. Follow care instructions on the label of UV-blocking clothes to maintain their protective feature.

• #1 Polymorphous Light Eruption: Practice Essentials, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/1119686-overview

  Polymorphous (polymorphic) light eruption (PMLE) is an acquired disease and is the most common of the idiopathic photodermatoses. Management of PMLE includes strict sun protection. This can be accomplished by using broad-spectrum sunscreens, seeking shade, and wearing protective clothing, including hats. Photohardening is beneficial and can be initiated early in spring to enhance tolerance of sun exposure. Topical and systemic immunosuppressants are employed for symptom management. The use of these agents should be tailored to the individual patient, with benefits weighed against risks. […] PMLE is a chronic condition; the average time to resolution is long and may extend to 30 years. A registry analysis (N = 97) by Gruber-Wackernagel et al determined that 74% of PMLE patients were still experiencing symptoms after 20 years. […] Richards et al found that emotional distress attributable to PMLE occurred in more than 40% of individuals. Women were more likely than men to associate more severe consequences with their PMLE and to experience more emotional distress.

• #1 Polymorphous light eruption | Beacon Health System

  https://www.beaconhealthsystem.org/library/diseases-and-conditions/polymorphous-light-eruption?content_id=CON-20257399

  Polymorphous light eruption usually goes away on its own without scarring within 10 days. People with severe or persistent rashes may need medication. […] Treatment of polymorphous light eruption usually isn’t needed because the rash usually goes away on its own within 10 days. If your symptoms are severe, your health care provider may prescribe anti-itch medicine (a corticosteroid cream or pill). […] Your health care provider may suggest phototherapy to prevent seasonal episodes of polymorphous light eruption if you have disabling symptoms. This exposes the skin to small doses of UVA or UVB light that helps your skin be less sensitive to light. It mimics the increased exposure you would experience during a summer. […] Self-care measures that may help ease signs and symptoms include: Applying anti-itch cream. Try a nonprescription anti-itch cream, which may include products containing at least 1% hydrocortisone. Taking antihistamines. If itching is a problem, oral antihistamines may help. Using cold compresses. Apply a towel dampened with cool tap water to the affected skin. Or take a cool bath. Leaving blisters alone. To speed healing and avoid infection, leave blisters intact. If needed, you can lightly cover blisters with gauze. Taking a pain reliever. A nonprescription pain medication may help reduce inflammation and pain. Protect the rash from further sun exposure. When you go outside, cover the area where the rash developed.

• #1 Polymorphous Light Eruption – UF Health

  https://ufhealth.org/conditions-and-treatments/polymorphous-light-eruption

  Polymorphous light eruption (PMLE) is a common skin reaction in people who are sensitive to sunlight (ultraviolet light). […] Your provider will examine your skin. Usually, your provider can diagnose PMLE based on your description of the symptoms. […] Steroid creams or ointments containing vitamin D may be prescribed by your provider. They are used 2 or 3 times a day at the start of the eruption. Steroid or other types of pills may be used for more severe cases. […] Protecting your skin from the sun can help prevent PMLE symptoms: […] Call for an appointment with your provider if PMLE symptoms do not respond to treatments.

• #1 Dermatology – Polymorphic Light Eruption :: Northern Care Alliance

  https://www.northerncarealliance.nhs.uk/patient-information/patient-leaflets/dermatology-polymorphic-light-eruption?q=%2Fpatient-information%2Fpatient-leaflets%2Fdermatology-polymorphic-light-eruption

  Some people with PLE may be able to increase the resistance of their skin at home. This involves going outside for short periods in the spring to build up your resistance. […] There is some research suggesting that fish oil rich in omega 3 oils can help some patients with PLE. […] Some research has also suggested that another supplement, Polypodium leucotomos extract (Fernblock in Heliocare tablets), can be helpful in some cases.

• #1 Polymorphic light eruption (PMLE) — DermNet

  https://dermnetnz.org/topics/polymorphic-light-eruption

  General measures include broad-spectrum 50+ SPF UVA/UVB sunscreen, sun protective clothing, and avoiding sunlight. […] Specific measures include potent topical corticosteroids such as betamethasone dipropionate 0.05% or mometasone 0.1% ointment for the body and weaker topical corticosteroids for the face such as hydrocortisone 1% ointment. […] PMLE may be lifelong although 60% of people see improvement or resolution over 15 years and 75% of people in 30 years.

• #2 Polymorphous Light Eruption (PMLE): Symptoms, Causes & Treatments

  https://my.clevelandclinic.org/health/diseases/17888-polymorphous-light-eruption-pmle

  Polymorphous light eruption (PMLE) is a common skin rash generally caused by exposure to the suns ultraviolet (UV) light. […] PMLE typically resolves on its own without treatment. […] People living with PMLE should avoid exposure to sunlight, especially between 11 a.m. and 3 p.m., when UV rays are strongest. Using high SPF, broad-spectrum sunscreen, and wearing protective clothing helps minimize UV light exposure. […] For severe rashes, your provider may prescribe: Antihistamines, Hydroxychloroquine, Immunosuppressants, Topical corticosteroids or tacrolimus. […] Your healthcare provider can suggest ways to protect your skin from UV light and prevent PMLE.

• #2 Polymorphous light eruption – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/polymorphous-light-eruption/symptoms-causes/syc-20355868

  Polymorphous light eruption usually goes away on its own without scarring within 10 days. People with severe or persistent rashes may need medicine. […] Polymorphous light eruption rashes look similar to rashes caused by other diseases, some of which are serious. So it’s important to get a prompt diagnosis and treatment. […] Seek immediate medical care if your rash: Is widespread. Is painful. Comes with a fever. […] The exact cause of polymorphous light eruption isn’t understood. The rash appears in people who have developed sensitivity to sunlight, especially ultraviolet (UV) radiation from the sun or other sources, such as tanning beds. This is called photosensitivity. It leads to immune system activity that causes a rash. […] With polymorphous light eruption, sensitivity to sunlight lessens with repeated exposure. Features of polymorphous light eruption are somewhat predictable: An episode is most likely to occur after the first one or two times of sun exposure after a long period of no exposure, such as in spring or early summer. Episodes are less likely to happen as the summer progresses. After the first episode, it’s likely to happen each year. Some people gradually become less sensitive over several years and eventually no longer experience the yearly rash. […] Anyone can develop polymorphous light eruption, but several things can increase your risk of the condition: Being female. Having skin that sunburns easily. Living in northern regions. Having a family history of the condition.

• #2 Polymorphic Light Eruption – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK430886/

  Polymorphic light eruption is the most common form of immunologically mediated photosensitivity dermatoses. Exposure to sunlight in spring or summer results in an irritable rash that resolves within a few days, providing further exposure is avoided. […] Management requires determining what provokes the eruption and then attempting to minimize this, while at the same time gradually increasing exposure to induce hardening. […] These healthcare professionals should educate the patients on prevention which includes wearing appropriate garments when going outside and use ample sunscreen frequently.

• #2 Polymorphous Light Eruption – UF Health

  https://ufhealth.org/conditions-and-treatments/polymorphous-light-eruption

  Polymorphous light eruption (PMLE) is a common skin reaction in people who are sensitive to sunlight (ultraviolet light). […] Your provider will examine your skin. Usually, your provider can diagnose PMLE based on your description of the symptoms. […] Steroid creams or ointments containing vitamin D may be prescribed by your provider. They are used 2 or 3 times a day at the start of the eruption. Steroid or other types of pills may be used for more severe cases. […] Protecting your skin from the sun can help prevent PMLE symptoms: […] Call for an appointment with your provider if PMLE symptoms do not respond to treatments.

• #2 Polymorphous light eruption – Symptoms, diagnosis and treatment | BMJ Best Practice US

  https://bestpractice.bmj.com/topics/en-us/626

  Polymorphous light eruption typically onsets during adolescence and young adulthood. […] Mainly affects women. […] Typically, manifests after exposure to intense ultraviolet radiation (UVR); clinical symptoms last several days and remission occurs without complication. […] Papules/papulovesicles and plaques on exposed sites are characteristic. […] Topical corticosteroid creams or lotions are the mainstay of therapy, with the addition of oral corticosteroids and nonsteroidal anti-inflammatory drugs (NSAIDs) in severe disease. […] Prophylaxis is an important part of management with avoidance of sun exposure, physical UVR protection, and light hardening.

• #2 5 Quick Facts About Polymorphous Light Eruption

  https://www.sanovadermatology.com/how-to-protect-yourself-from-the-sun/polymorphous-light-eruption-am-i-allergic-to-the-sun/

  Polymorphous light eruption (PMLE) may sound like something out of a science fiction film, but this skin condition is surprisingly common. Here are five quick facts about PMLE. […] The simple answer is: “It’s a rash,” says Dr. Miriam Hanson, a board certified Dermatologist in Austin, Texas, “that appears after sun exposure.” PMLE is commonly confused with hives but it isn’t quite the same thing. […] Prevention is the best course of action. “If PMLE runs in your family or if you’ve had an incident in the past, limit your sun exposure by avoiding direct sunlight and take skin care precautions like long sleeves and sunscreen,” shares Dr. Hanson. Your doctor may prescribe an anti-itch cream or anti-inflammatory medication if you are especially uncomfortable. But most cases of PMLE clear up on their own with no addition intervention. “At Sanova Dermatology, we also prescribe Phototherapy in selected patients,” says Dr. Hanson. If you develop blisters as a result of a PMLE flair, do not irritate them and see your doctor for proper care. […] If you or someone you care about has PMLE be sure and contact us to make an appointment to learn more.

• #2

  https://www.nursingcenter.com/journalarticle?Article_ID=5705365&Journal_ID=849729&Issue_ID=5705176

  ABSTRACT: While there are a number of skin rashes associated with photosensitivity, only one produces a distinctive rash with fixed urticaria, macular erythema, and papulovesicles forming small papules and plaques. This polymorphous light eruption requires aggressive broad spectrum UV protection, topical steroids for pruritus, and paradoxically sometimes UV light treatment to „harden” the skin making skin more resistant to rashing when exposed to the sun. […] Skin care recommendations: The patient was instructed to use a broad-spectrum (UVA/UVB blocking) sunscreen with SPF 30 or greater when exposed to the sun, especially in the first exposures in the springtime. […] PMLE is a common immunologically mediated photodermatosis that occurs in temperate climates. The variable appearance of pruritic skin lesions occurs most commonly in the spring or early summer on sun-exposed areas (Gruber-Wackernagel et al., 2014). Making this clinical diagnosis and recommending broad-spectrum UV avoidance and protection will most often lead to prompt resolution without further treatment or diagnostic testing (Bissonnette et al., 2012).

• #2 Polymorphous light eruption | Lima Memorial Health System

  https://www.limamemorial.org/mobile/health-library/HIE%20Multimedia/1/001477

  Polymorphous light eruption (PMLE) is a common skin reaction in people who are sensitive to sunlight (ultraviolet light). […] Your provider will examine your skin. Usually, your provider can diagnose PMLE based on your description of the symptoms. […] Steroid creams or ointments containing vitamin D may be prescribed by your provider. They are used 2 or 3 times a day at the start of the eruption. Steroid or other types of pills may be used for more severe cases. […] Phototherapy may also be prescribed. Phototherapy is a medical treatment in which your skin is carefully exposed to ultraviolet light. This may help your skin become used to (sensitized to) the sun. […] Call for an appointment with your provider if PMLE symptoms do not respond to treatments. […] Protecting your skin from the sun can help prevent PMLE symptoms: Avoid sun exposure during hours of peak sun ray intensity. Use sunscreen. Sun protection with broad spectrum sunblock that works against UVA rays is important. Apply generous amounts of sunscreen with a sun protection factor (SPF) of at least 30. Pay special attention to your face, nose, ears, and shoulders. Apply sunscreen 30 minutes before sun exposure so that it has time to penetrate the skin. Re-apply after swimming and every 2 hours while you are outdoors. Wear a sun hat. Wear sunglasses with UV protection. Use a lip balm with sunscreen.

• #2 Interventions for polymorphic light eruption

  https://pmc.ncbi.nlm.nih.gov/articles/PMC6485352/

  To assess the effects of interventions in the prophylaxis and treatment of polymorphic light eruption. […] Preventive management is routinely advocated by sun avoidance between 11 a.m. and 3 p.m., use of protective clothing, and application of sunscreen. […] Topical steroids are widely used for mild episodes of PLE. An immediate short course of oral prednisolone considerably reduces the severity of itch and rash in people who suffer from occasional, severe attacks of PLE on vacation. […] PsoralenUVA (PUVA), narrowband (NBUVB) or broadband UVB (BBUVB) phototherapy is currently the mainstay of treatment for more severe PLE. […] There are many reported treatments for PLE. Sun protection, corticosteroids and desensitisation phototherapy appear to be the current mainstay of treatment, with immunomodulator agents as secondline treatment.

• #2 Polymorphic light eruption

  https://www.nhs.uk/conditions/polymorphic-light-eruption/

  It’s sometimes possible to increase the resistance of your skin to the sun. […] A GP or dermatologist may advise you to try increasing the resistance of your skin at home. […] People with polymorphic light eruption are at greater risk of vitamin D deficiency, as a certain amount of sun exposure is needed to make your own vitamin D. […] Many people with polymorphic light eruption find their skin improves over the years.

• #2 Polymorphic light eruption (PMLE) — DermNet

  https://dermnetnz.org/topics/polymorphic-light-eruption

  Polymorphic light eruption (PMLE) is a seasonal, acquired, idiopathic photodermatosis occurring in spring and early summer. […] Patients with PMLE can develop a tolerance during summer months. […] PMLE is a delayed hypersensitivity reaction in the skin to unknown endogenous cutaneous photo-induced antigens. […] The following factors must be considered when determining pathogenesis and when implementing protective measures: It is primarily caused by either UVA (7590%) or UVB light alone or UVA and UVB light concurrently. […] PMLE persists for several days and can worsen if the affected skin is exposed to further sunlight before resolution of the previous eruption. It resolves without scarring. […] There is a phenomenon called the skin hardening effect where chronic exposure to sunlight leads to skin changes including increased melanin and thickening of the stratum corneum.

• #2 Polymorphous Light Eruption Symptoms, Causes, and Treatment

  https://www.healthline.com/health/polymorphous-light-eruption

  PMLE is generally treatable with both home remedies and medical interventions. […] Gradual hardening is one form of treating PMLE. This can be done through careful and measured exposure to sunlight, or it can be achieved through the use of phototherapy. […] After the rash has already appeared, a doctor may prescribe corticosteroids to help alleviate itchiness or burning. […] If you have PMLE and you find that its affecting your well-being, a healthcare professional can advise you on appropriate strategies to manage these feelings. […] To reduce the effects of PMLE, the American Academy of Dermatology (AAD) recommends seeking shade and applying sunscreen. […] The best way to address PMLE is to avoid direct sun during the strongest parts of the day, wear appropriate sunscreen, and wear clothing that covers your skin.

• #2 Polymorphous light eruption – Augusta HealthSearchClose SearchSearch IconSearch IconClose Search IconMobile Menu IconMobile Menu Close IconInstagramFacebookTwitterYoutube

  https://www.augustahealth.com/disease/polymorphous-light-eruption/

  Self-care measures that may help ease your signs and symptoms include: Applying anti-itch cream. Try an over-the-counter (nonprescription) anti-itch cream, which may include products containing at least 1 percent hydrocortisone. Taking antihistamines. If itching is a problem, oral antihistamines may help. Using cold compresses. Apply a towel dampened with cool tap water to the affected skin, or take a cool bath. Leaving blisters alone. To speed healing and avoid infection, leave blisters intact. If needed, you can lightly cover blisters with gauze. Taking a pain reliever. An over-the-counter pain medication may help reduce redness or pain. These include ibuprofen (Advil, Motrin IB, others), acetaminophen (Tylenol, others) and naproxen sodium (Aleve, others). […] To lessen the likelihood of recurring episodes of polymorphous light eruption, take the following precautions: Avoid the sun between 10 a.m. and 2 p.m. Because the sun’s rays are most intense during this time, try to schedule outdoor activities for other times of the day. Use sunscreen. Fifteen to 30 minutes before going outdoors, apply a broad-spectrum sunscreen, one that provides protection from both UVA and UVB light. Use a sunscreen with a sun protection factor (SPF) of at least 30. Apply sunscreen generously, and reapply every two hours — or more often if you’re swimming or perspiring. If you’re using a spray sunscreen, be sure to cover the entire area completely. Cover up. For protection from the sun, wear tightly woven clothing that covers your arms and legs and a broad-brimmed hat, which provides more protection than does a baseball cap or golf visor. Consider wearing clothing designed to provide sun protection. Look for clothes labeled with an ultraviolet protection factor (UPF) of 40 to 50. Follow care instructions on the label of UV-blocking clothes to maintain their protective feature.

• #2 Polymorphic Light Eruption (PMLE): Symptoms and Treatment

  https://patient.info/skin-conditions/sun-and-sunburn/polymorphic-light-eruption

  Polymorphic light eruption is a skin rash that can happen when you go out in the sun. […] Polymorphic light eruption (PMLE) is a rash which comes on after being in strong sunlight. […] The rash generally clears up within a week if you stay out of the sun. […] Prevention is definitely better than cure. If you have had PMLE in the past, you are quite likely to get it again the following year when you start to go out in the sun. […] Sunscreen is helpful to prevent the rash. […] If you do develop PMLE, there are several things you can try to ease the symptoms: A mild topical corticosteroids like hydrocortisone can help the redness to settle down. […] If the above treatments are not sufficient, you may be referred to a dermatologist. […] Although no treatment stops polymorphic light eruption (PMLE) developing for ever, the outlook is good. The rash heals completely, although while it lasts it may be uncomfortable or unsightly.

• #2

  https://www.nursingcenter.com/journalarticle?Article_ID=5705365&Journal_ID=849729&Issue_ID=5705176

  In many patients, PMLE fades over days to several weeks without treatment. Patients with significant pruritus are treated effectively with oral and topical steroids (Ling et al., 2017). Phototherapy with narrow-band UVB, UVA, and PUVA can induce „hardening” and may help patients with recalcitrant disease (Ling et al., 2017). Several natural remedies have been recommended for PMLE including B-carotene and nicotinamide 2-3 g daily. The latter was shown to lead to resolution of all symptoms in 60% of patients in an uncontrolled trial of 42 patients (Lembo Raimondo, 2018).

• #2 Polymorphous Light Eruption: Practice Essentials, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/1119686-overview

  Polymorphous (polymorphic) light eruption (PMLE) is an acquired disease and is the most common of the idiopathic photodermatoses. Management of PMLE includes strict sun protection. This can be accomplished by using broad-spectrum sunscreens, seeking shade, and wearing protective clothing, including hats. Photohardening is beneficial and can be initiated early in spring to enhance tolerance of sun exposure. Topical and systemic immunosuppressants are employed for symptom management. The use of these agents should be tailored to the individual patient, with benefits weighed against risks. […] PMLE is a chronic condition; the average time to resolution is long and may extend to 30 years. A registry analysis (N = 97) by Gruber-Wackernagel et al determined that 74% of PMLE patients were still experiencing symptoms after 20 years. […] Richards et al found that emotional distress attributable to PMLE occurred in more than 40% of individuals. Women were more likely than men to associate more severe consequences with their PMLE and to experience more emotional distress.

• #2 Polymorphous Light Eruption: A Guide to Understanding the Rash

  https://www.doctorshubnepal.com/diseases-conditions/polymorphous-light-eruption-pmle

  If you experience any of the following symptoms, you should seek medical attention: If your symptoms are severe or persistent, you should seek medical attention. If you experience signs of infection such as increased redness, swelling, or pus, you should seek medical attention. If you experience scarring or blistering that persists for an extended period of time, you should seek medical attention.

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