Materiały źródłowe

• #1

  https://content.irisoncology.com/library/recurrent-breast-cancer

  Recurrent breast cancer is breast cancer that comes back after initial treatment. Although the initial treatment is aimed at eliminating all cancer cells, a few may have evaded treatment and survived. These undetected cancer cells multiply, becoming recurrent breast cancer. […] Recurrent breast cancer may occur months or years after your initial treatment. The cancer may come back in the same place as the original cancer (local recurrence), or it may spread to other areas of your body (distant recurrence). […] Signs and symptoms of recurrent breast cancer vary depending on where the cancer comes back. […] In a local recurrence, cancer reappears in the same area as your original cancer. […] Signs and symptoms of local recurrence within the same breast may include: A new lump in your breast or irregular area of firmness. Changes to the skin of your breast. Skin inflammation or area of redness. Nipple discharge.

• #2 Recurrent breast cancer | UM Health-Sparrow

  https://www.uofmhealthsparrow.org/departments-conditions/conditions/recurrent-breast-cancer

  Recurrent breast cancer may occur months or years after your initial treatment. The cancer may come back in the same place as the original cancer (local recurrence), or it may spread to other areas of your body (distant recurrence). […] Signs and symptoms of recurrent breast cancer vary depending on where the cancer comes back. […] In a local recurrence, cancer reappears in the same area as your original cancer. […] Signs and symptoms of local recurrence within the same breast may include: A new lump in your breast or irregular area of firmness. Changes to the skin of your breast. Skin inflammation or area of redness. Nipple discharge. […] A regional breast cancer recurrence means the cancer has come back in the nearby lymph nodes. […] Signs and symptoms of regional recurrence may include a lump or swelling in the lymph nodes located: Under your arm. Near your collarbone. In the groove above your collarbone. In your neck.

• #3 Recognizing and Managing Recurrent Breast Cancer: Signs and Treatment Options

  https://aocancer.com/blog/recognizing-and-managing-recurrent-breast-cancer-signs-and-treatment-options

  Breast cancer is often successfully treated, especially when it is detected early. That fact remains, however, breast cancer returns for some patients after the initial treatment plan is complete. This is what is known as recurrent breast cancer. […] Recurrent breast cancer is caused by cancer cells that were not completely destroyed during the initial treatment process. Those cells can lay dormant (inactive) for several months, or years before they start to grow again. […] While breast cancer recurrence is most common in the first five years after treatment is complete, it can recur months, or many years, following treatment. […] The signs and symptoms of recurrent breast cancer can vary from patient to patient and may look different based on where the cancer comes back. Its important that you follow your doctors recommended follow-up imaging schedule to look for cancer that cant be detected by feeling the breast.

• #4 Recurrent breast cancer | Altru Health System

  https://www.altru.org/health-library/conditions/recurrent-breast-cancer

  Recurrent breast cancer is breast cancer that comes back after initial treatment. Although the initial treatment is aimed at eliminating all cancer cells, a few may have evaded treatment and survived. These undetected cancer cells multiply, becoming recurrent breast cancer. […] Recurrent breast cancer may occur months or years after your initial treatment. The cancer may come back in the same place as the original cancer (local recurrence), or it may spread to other areas of your body (distant recurrence). […] Signs and symptoms of recurrent breast cancer vary depending on where the cancer comes back. […] In a local recurrence, cancer reappears in the same area as your original cancer. […] Signs and symptoms of local recurrence within the same breast may include: A new lump in your breast or irregular area of firmness. Changes to the skin of your breast. Skin inflammation or area of redness. Nipple discharge.

• #5 Recurrent Breast Cancer: Causes, Symptoms, and Treatments | SELF

  https://www.self.com/story/recurrent-breast-cancer

  Recurrent breast cancer is breast cancer that comes back after initial treatment. Although the initial treatment is aimed at eliminating all cancer cells, a few may have evaded treatment and survived. These undetected cancer cells multiply, becoming recurrent breast cancer. […] Recurrent breast cancer may occur months or years after your initial treatment. The cancer may come back in the same place as the original cancer (local recurrence), or it may spread to other areas of your body (distant recurrence). […] Signs and symptoms of recurrent breast cancer vary depending on where the cancer comes back. […] In a local recurrence, cancer reappears in the same area as your original cancer. […] If you’ve undergone lumpectomy, the cancer could recur in the remaining breast tissue. If you’ve undergone mastectomy, the cancer could recur in the tissue that lines the chest wall or in the skin.

• #6 Breast cancer recurrence symptoms | Breast Cancer Now

  https://breastcancernow.org/about-breast-cancer/diagnosis/breast-cancer-recurrence/breast-cancer-recurrence-symptoms

  The risk of breast cancer recurring is higher in the first few years and usually reduces as time goes on. […] However, recurrence can happen even many years after treatment. […] Its important to continue to be breast and body aware and report any changes to your treatment team or GP. […] Whether youve had breast-conserving surgery or a mastectomy with or without reconstruction, its important to be aware of any changes to the breast, chest or surrounding area, even if youre having follow-up appointments or regular mammograms. […] If you have pain that gets worse or is severe, contact your treatment team or GP. […] Its also important to be aware of any new changes in the other breast and to report these as soon as possible.

• #7 Risks, Symptoms, and Treatments for Breast Cancer Recurrence – Ezra

  https://ezra.com/blog/breast-cancer-recurrence

  Breast cancer that comes back within five years of diagnosis and initial treatment is called early recurrence. Breast cancer that returns more than five years after diagnosis and initial treatment is called late recurrence. […] A bilateral mastectomy, or surgical removal of both breasts, significantly reduces your chances of breast cancer relapse. However, there is still a minimal chance that residual breast tissue or cancer cells could recur on the chest wall. […] Local breast cancer recurrence is when cancer comes back in the same area that the first tumor was found. […] Regional recurrence is when cancer reappears in the lymph nodes in the armpit or collarbone area near where the tumor was initially diagnosed. […] Distant breast cancer recurrence is when breast cancer has spread (metastasis) to another organ or part of your body, such as your lungs, bones, or brain. Though rare, distance recurrence can also occur in the opposite breast. […] You can assess your risk of cancer or cancer recurrence by taking ezras know-your-risk quiz, which evaluates questions about your lifestyle and medical history.

• #8 Breast Cancer Recurrence | Breast Cancer Surgery Melbourne, VIC

  https://www.melbournebreastcancersurgery.com.au/breast-cancer-recurrence.html

  Cells from the original breast cancer diagnosis break away and hide nearby in the breast (called local recurrence) or spread elsewhere in the body (called distant recurrence); […] Treatment, including surgery, chemotherapy, radiotherapy and/or hormone therapy have not gotten rid of all these cancer cells from the body. […] Many recurrences are detected in the five years after diagnosis, especially after triple negative breast cancer. However, on occasions recurrence can occur more than 20 years after the first diagnosis. […] Your individual chance of breast cancer returning is also determinate on a number of factors including the type of breast cancer, tumour size, genetic factors and treatment types. […] If your breast cancer has spread to other parts to the body, known as distant recurrence, there are a number of possible symptoms, including: Fatigue, Breathlessness, Pain in your bones, Unexpected weight loss or change in appetite, Severe or ongoing headaches, Nausea.

• #9 Return of Breast Cancer after Treatment (Recurrence) | Susan G. Komen®

  https://www.komen.org/breast-cancer/treatment/recurrence/

  The goal of treating early breast cancer is to remove the cancer and keep it from coming back. A return of breast cancer is called a breast cancer recurrence. […] Most people diagnosed with breast cancer will never have a recurrence. However, everyone whos had breast cancer is at risk of recurrence. […] The risk of breast cancer recurrence varies greatly from person to person. Your health care provider cannot tell you whether or not you will have a recurrence, but they can give you some information about your risk. […] Breast cancer that recurs at the original site is called a local recurrence. A local recurrence is usually found on a mammogram, during a clinical breast exam by a health care provider or when you notice a change in or around your breast or underarm. […] Breast cancer that returns and spreads to other parts of the body is called a distant recurrence (metastasis). This is metastatic breast cancer and may also be called stage IV or advanced breast cancer.

• #10 Breast Cancer Recurrence – Tower Love Fund – Breast Cancer Explained

  https://www.towercancer.org/resource/breast-cancer-recurrence/

  Recurrent breast cancer occurs when breast cancer cells reappear in the area around the breast or in other areas of the body. […] A cancer recurrence occurs when breast cancer cells reappear in the area around the breast (local or regional recurrence) or in other areas of the body (distant metastasis). […] The first sign of a local recurrence can be a change in how your breast looks or feels, which is why women often identify a recurrence themselves. […] Changes in the physical exam that occur more than one to two years after the completion of radiation therapy should always be looked into immediately with mammograms and MRI. […] Local recurrence after mastectomy usually shows up as one or more pea-sized nodules on or under the skin near the scar. […] A regional recurrence is one in the lymph nodes in the armpit (axilla) or above the collarbone.

• #11 Breast Cancer Recurrence: Rates, Signs & Treatment

  https://my.clevelandclinic.org/health/diseases/8328-breast-cancer-recurrence

  Breast cancer recurrence is when cancer comes back after treatment. Recurrent breast cancer may develop where it started, or spread to nearby lymph nodes or to more distant areas of your body. […] Symptoms vary depending on where cancer started. For example, cancer that comes back in the same area as the original cancer (local cancer) causes different symptoms than regional cancer, which is breast cancer that’s spread to nearby lymph nodes. […] Local breast cancer recurrence may cause: Breast lumps or bumps on or under your chest. Nipple changes, such as flattening or nipple discharge. Swollen skin or skin that pulls near the lumpectomy site. Thickening on or near the surgical scar. Unusually firm breast tissue. […] Regional breast cancer recurrence may cause: Chronic chest pain. Difficulty swallowing. Pain, swelling or numbness in one arm or shoulder. Swollen lymph nodes in your armpit or in or around your collarbone area.

• #12 Treatment if your breast cancer comes back | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/breast-cancer/treatment/if-your-cancer-comes-back

  Many women have no more problems after their original treatment for breast cancer. But sometimes breast cancer comes back after treatment to try to cure it. This is called recurrent or relapsed breast cancer. […] Symptoms of recurrent breast cancer include: a lump called a nodule in the breast or scar, change in shape or size of the breast, swelling in the lymph nodes above and below the collarbone, the neck, and around the breastbone, changes in the shape or position of the nipple, redness or a skin rash around the breast. […] A locally advanced recurrence means that the breast cancer has spread beyond the breast to areas near or around the breast. But has not spread to other distant parts of the body.

• #13 Breast cancer recurrence symptoms | Breast Cancer Now

  https://breastcancernow.org/about-breast-cancer/diagnosis/breast-cancer-recurrence/breast-cancer-recurrence-symptoms/

  Most breast cancers dont come back after treatment, but its very common to worry about breast cancer returning. […] If breast cancer does come back, its known as recurrence. […] Its important to know what signs and symptoms to look out for. […] Be aware of any changes to your breast or chest area. […] If youve had breast-conserving surgery, the cancer could come back in the remaining breast tissue. […] If youve had a mastectomy, the cancer could come back in the chest wall or in the skin. […] Look for changes to the other breast too. Changes include: Swelling on your chest, in your armpit or around your collarbone, A change in shape or size, A change in skin texture, such as puckering or dimpling, The nipple has become pulled in (inverted) or looks different, for example changed position or shape, Liquid (discharge) that comes from the nipple without squeezing it, Swelling in the arm or hand, Redness or a rash on the skin, in or around the nipple or in the area of the mastectomy scar line of your treated breast, A lump or thickening that feels different (with your treated breast this could be on or away from the scar line).

• #14 Breast Cancer Recurrence: Causes, Symptoms, and Treatment | Breast Care Center Miami

  https://www.toplinemd.com/breast-care-center-of-miami/blog/breast-cancer-recurrence-causes-symptoms-and-treatment/

  When we talk about breast cancer recurrence, we refer to the breast cancer that has returned even after effective past treatment, at which point no existing cancer cells were detected. A person can be affected by recurrent breast cancer in just a few months or several years after the initial treatment process. […] Breast cancer recurrence symptoms change based on the location of the disease. In that sense, recurrent breast cancer can be local, regional, or distant. […] Local breast cancer recurrence symptoms are as follows: New lump formation in the chest wall or breast, Unusual firmness in the concentrated breast area, Complete or partial breast skin swelling, Red and irritated breast area, Nipple flattening and other potential changes, Changes around the original surgery scar/site include swelling, thickening, skin pulling, etc.

• #15

  https://content.irisoncology.com/library/recurrent-breast-cancer

  Signs and symptoms of local recurrence on the chest wall after a mastectomy may include: One or more painless nodules on or under the skin of your chest wall. A new area of thickening along or near the mastectomy scar. […] A regional breast cancer recurrence means the cancer has come back in the nearby lymph nodes. […] Signs and symptoms of regional recurrence may include a lump or swelling in the lymph nodes located: Under your arm. Near your collarbone. In the groove above your collarbone. In your neck. […] A distant (metastatic) recurrence means the cancer has traveled to distant parts of the body, most commonly the bones, liver and lungs. […] Signs and symptoms include: Persistent and worsening pain, such as chest, back or hip pain. Persistent cough. Difficulty breathing. Loss of appetite. Weight loss without trying. Severe headaches. Seizures.

• #16 Types and Symptoms of Recurrence, Living with Breast Cancer, CBCN

  https://cbcn.ca/en/symptoms-recurrence

  Signs and symptoms of a regional breast cancer recurrence may look like: Chronic chest pain, Difficulty swallowing, Pain, swelling, or numbness in one arm or shoulder, Lump or swelling in the lymph nodes located: Under your arm, Near or above your collarbone, Near the breastbone, In your neck. […] Signs and symptoms of a distant breast cancer recurrence may look like: Bone pain or pain in the affected area that is persistent, worsens over time, and may be worse at night, Severe headaches, Numbness or weakness, Vision problems, Chronic dry cough, Difficulty breathing, Dizziness or balance problems, Seizures, Extreme fatigue, Loss of appetite, nausea, and weight loss.

• #17 Recurrent breast cancer | Altru Health System

  https://www.altru.org/health-library/conditions/recurrent-breast-cancer

  A regional breast cancer recurrence means the cancer has come back in the nearby lymph nodes. […] Signs and symptoms of regional recurrence may include a lump or swelling in the lymph nodes located: Under your arm. Near your collarbone. In the groove above your collarbone. In your neck. […] A distant (metastatic) recurrence means the cancer has traveled to distant parts of the body, most commonly the bones, liver and lungs. […] Signs and symptoms include: Persistent and worsening pain, such as chest, back or hip pain. Persistent cough. Difficulty breathing. Loss of appetite. Weight loss without trying. Severe headaches. Seizures.

• #18 Breast cancer recurrence | Macmillan Cancer Support

  https://www.macmillan.org.uk/cancer-information-and-support/breast-cancer/breast-cancer-recurrence

  Sometimes breast cancer comes back in the lymph nodes in the armpit, close to the breastbone or in the lower neck. This is called a regional recurrence. […] A local or regional breast cancer recurrence can occur on its own or at the same time as secondary breast cancer. […] If tests show the cancer has spread to other parts of the body, such as the bones or lungs, this is called secondary breast cancer.

• #19

  https://content.irisoncology.com/library/recurrent-breast-cancer

  Signs and symptoms of local recurrence on the chest wall after a mastectomy may include: One or more painless nodules on or under the skin of your chest wall. A new area of thickening along or near the mastectomy scar. […] A regional breast cancer recurrence means the cancer has come back in the nearby lymph nodes. […] Signs and symptoms of regional recurrence may include a lump or swelling in the lymph nodes located: Under your arm. Near your collarbone. In the groove above your collarbone. In your neck. […] A distant (metastatic) recurrence means the cancer has traveled to distant parts of the body, most commonly the bones, liver and lungs. […] Signs and symptoms include: Persistent and worsening pain, such as chest, back or hip pain. Persistent cough. Difficulty breathing. Loss of appetite. Weight loss without trying. Severe headaches. Seizures.

• #20 Stage 4 (IV) Breast Cancer: Survival Rates, Treatment & Prognosis

  https://www.nationalbreastcancer.org/breast-cancer-stage-4/

  Stage 4 breast cancer is advanced breast cancer that has metastasized, or spread, from the original location in the breast to other organs of the body, such as the bones, lungs, liver, or brain. Stage 4 breast cancer is also called metastatic breast cancer or breast cancer recurrence. […] The symptoms of Stage 4 breast cancer may be different depending on what part of the body the breast cancer has spread to. The most common areas for breast cancer to spread to are the bones, lungs, liver, or brain. If the cancer cells are invasive lobular carcinoma (ILC), those cells may travel to additional organs, such as the uterus, ovaries, stomach, or colon. […] The bones, particularly the spine, pelvis, and thigh bones, is the most common place for breast cancer to spread to, affecting approximately 70% of Stage 4 patients.

• #21 Stage 4 (IV) Breast Cancer: Survival Rates, Treatment & Prognosis

  https://www.nationalbreastcancer.org/breast-cancer-stage-4/

  After bones, the lungs are the second most common area of the body for breast cancer to spread to, affecting approximately 60% of Stage 4 breast cancer patients. […] Approximately 50% of individuals with Stage 4 breast cancer will develop liver metastases at some point. […] Brain metastasis occurs in approximately 10-15% of women with Stage 4 breast cancer. […] Not all Stage 4 breast cancer has observable signs or symptoms. But if breast cancer has spread to the bones, the following signs and symptoms may be felt: Severe, progressive bone pain, particularly in the spine, ribs, pelvis, or long bones in the arms and legs; Swelling of joints within the skeletal system; Weak or fragile bones, not as a result of osteoporosis; Weakness in the arms or legs; High levels of calcium in the blood (hypercalcemia).

• #22 Breast Cancer Recurrence | Breast Cancer Surgery Melbourne, VIC

  https://www.melbournebreastcancersurgery.com.au/breast-cancer-recurrence.html

  Factors such as initial tumour size, number of nodes involved, and receptor status play into the risk of late recurrence, but tumour biology appears to have the greatest effect, and research is actively looking for ways to look at gene expression and copy number to predict risk. […] The most common site of distant breast cancer metastases, occurring in around 70% of people with metastatic breast cancer, is the bones. […] Symptoms and Detection While bone metastasis may cause pain, that is not always the case. […] Breast cancer metastases to the liver are also common. […] Symptoms of brain metastases often include: Headaches, Visual changes, Dizziness, Seizures (sometimes a seizure is the first symptom). […] Breast cancer can spread to nearly any region of the body.

• #23 Stage 4 (IV) Breast Cancer: Survival Rates, Treatment & Prognosis

  https://www.nationalbreastcancer.org/breast-cancer-stage-4/

  Stage 4 breast cancer is advanced breast cancer that has metastasized, or spread, from the original location in the breast to other organs of the body, such as the bones, lungs, liver, or brain. Stage 4 breast cancer is also called metastatic breast cancer or breast cancer recurrence. […] The symptoms of Stage 4 breast cancer may be different depending on what part of the body the breast cancer has spread to. The most common areas for breast cancer to spread to are the bones, lungs, liver, or brain. If the cancer cells are invasive lobular carcinoma (ILC), those cells may travel to additional organs, such as the uterus, ovaries, stomach, or colon. […] The bones, particularly the spine, pelvis, and thigh bones, is the most common place for breast cancer to spread to, affecting approximately 70% of Stage 4 patients.

• #24 Breast Cancer Recurrence: Types, Symptoms and Risk

  https://www.cancercenter.com/cancer-types/breast-cancer/types/rare-breast-cancer-types/recurrent-breast-cancer

  Even after initial treatment is complete and tests show no sign of disease, there is a chance breast cancer may return. When that happens, its called recurrent breast cancer. In most cases, recurrent cancers appear within the first three years after treatment. But in some cases, breast cancer recurrence may develop many years later, either locally or in distant organs in the body. […] The signs of cancer recurrence depend on where the cancer resurfaces. The patient might not see or feel any signs of a local recurrence, and, if she does, it’ll probably be a slight change in or around the breast or underarm area. More often than not, the patient’s provider finds evidence of a local recurrence during a physical exam or mammogram. […] A distant recurrence will typically produce some symptoms, but because many of those breast cancer symptoms are common to other health problems, it can be hard to tell if theyre due to a distant recurrence or something else. Have an open conversation with the cancer care team about any symptoms, especially if they last more than two weeks.

• #25 Assessing Mode of Recurrence in Breast Cancer to Identify an Optimised Follow-Up Pathway: 10-Year Institutional Review

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10495471/

  Breast cancer surveillance programmes ensure early identification of recurrence which maximises overall survival. […] The aim was to assess diagnostic modalities for recurrent breast cancer with a focus on evaluating the role of annual clinical examination. […] A total of 65/140 (46%) patients were diagnosed clinically, either by self-detection or clinical examination, while 75/140 (54%) were diagnosed radiologically. […] Clinical examination provides little value in diagnosing recurrence (5%) and surveillance programmes may benefit from reduced focus on such a modality. […] The median time to recurrence in all patients was 48 months (range 22-63 months). […] The current study demonstrates that less than 5% of patients with breast cancer recurrence are diagnosed at routine clinical examination as part of a scheduled breast cancer clinical surveillance programme. […] It is likely that annual clinical examination provides little value in the diagnosis of recurrence, and surveillance programmes may benefit from reduced focus on such a modality in diagnosing recurrent breast cancer with potential benefits on surgeon workload.

• #26

  https://content.irisoncology.com/library/recurrent-breast-cancer

  Recurrent breast cancer is breast cancer that comes back after initial treatment. Although the initial treatment is aimed at eliminating all cancer cells, a few may have evaded treatment and survived. These undetected cancer cells multiply, becoming recurrent breast cancer. […] Recurrent breast cancer may occur months or years after your initial treatment. The cancer may come back in the same place as the original cancer (local recurrence), or it may spread to other areas of your body (distant recurrence). […] Signs and symptoms of recurrent breast cancer vary depending on where the cancer comes back. […] In a local recurrence, cancer reappears in the same area as your original cancer. […] Signs and symptoms of local recurrence within the same breast may include: A new lump in your breast or irregular area of firmness. Changes to the skin of your breast. Skin inflammation or area of redness. Nipple discharge.

• #27 Types and Symptoms of Recurrence, Living with Breast Cancer, CBCN

  https://cbcn.ca/en/symptoms-recurrence

  A breast cancer recurrence happens when breast cancer returns months or years after you’ve finished treatment and are in remission. […] When breast cancer recurs, it can be local, regional, or distant and the signs and symptoms of a breast cancer recurrence varies, depending on where it comes back. […] Signs and symptoms of a local breast cancer recurrence may look like: Breast lump or bumps on or under the chest, Unusually firm breast tissue, Swelling on your chest, in your armpit, or around your collarbone, A change in the shape or size of the breast or chest area, Nipple changes, such as flattening or nipple discharge, An inverted nipple (pulled in) or a nipple that looks different, Redness or a rash on or around the nipple or on the skin, Swollen, thickening skin or skin that pulls near or on the lumpectomy scar, A change in skin texture, such as puckering or dimpling, Swelling in the arm or hand, One or more painless nodules on or under the skin of your chest wall.

• #28 Recognizing and Managing Recurrent Breast Cancer: Signs and Treatment Options

  https://aocancer.com/blog/recognizing-and-managing-recurrent-breast-cancer-signs-and-treatment-options

  If the cancer returns in the breast tissue, you may experience the following symptoms: Discharge from the nipple, New lump in the breast, Irregular firmness in the breast, Skin inflammation, Redness, Other skin changes. […] Cancer in the chest wall following a mastectomy (the surgical removal of one or both breasts) may have the following signs and symptoms: Nodules form on or under the skin of the chest wall, New thickening near the scar line of the mastectomy. […] Regional breast cancer typically includes a lump or swelling in lymph nodes located in the following areas: In your neck, Under your arm, Near or above your collarbone. […] Signs and symptoms associated with distant breast cancer recurrence typically include: Ongoing and worsening pain, such as the chest or hip, Sudden and unintentional weight loss, Persistent cough, Bone pain, Jaundice (yellowing of the skin or eyes), Difficulty breathing, Seizures.

• #29 Breast cancer recurrence symptoms | Breast Cancer Now

  https://breastcancernow.org/about-breast-cancer/diagnosis/breast-cancer-recurrence/breast-cancer-recurrence-symptoms/

  Most breast cancers dont come back after treatment, but its very common to worry about breast cancer returning. […] If breast cancer does come back, its known as recurrence. […] Its important to know what signs and symptoms to look out for. […] Be aware of any changes to your breast or chest area. […] If youve had breast-conserving surgery, the cancer could come back in the remaining breast tissue. […] If youve had a mastectomy, the cancer could come back in the chest wall or in the skin. […] Look for changes to the other breast too. Changes include: Swelling on your chest, in your armpit or around your collarbone, A change in shape or size, A change in skin texture, such as puckering or dimpling, The nipple has become pulled in (inverted) or looks different, for example changed position or shape, Liquid (discharge) that comes from the nipple without squeezing it, Swelling in the arm or hand, Redness or a rash on the skin, in or around the nipple or in the area of the mastectomy scar line of your treated breast, A lump or thickening that feels different (with your treated breast this could be on or away from the scar line).

• #30 Breast Cancer Recurrence: Causes, Symptoms, and Treatment | Breast Care Center Miami

  https://www.toplinemd.com/breast-care-center-of-miami/blog/breast-cancer-recurrence-causes-symptoms-and-treatment/

  When we talk about breast cancer recurrence, we refer to the breast cancer that has returned even after effective past treatment, at which point no existing cancer cells were detected. A person can be affected by recurrent breast cancer in just a few months or several years after the initial treatment process. […] Breast cancer recurrence symptoms change based on the location of the disease. In that sense, recurrent breast cancer can be local, regional, or distant. […] Local breast cancer recurrence symptoms are as follows: New lump formation in the chest wall or breast, Unusual firmness in the concentrated breast area, Complete or partial breast skin swelling, Red and irritated breast area, Nipple flattening and other potential changes, Changes around the original surgery scar/site include swelling, thickening, skin pulling, etc.

• #31

  https://content.irisoncology.com/library/recurrent-breast-cancer

  Signs and symptoms of local recurrence on the chest wall after a mastectomy may include: One or more painless nodules on or under the skin of your chest wall. A new area of thickening along or near the mastectomy scar. […] A regional breast cancer recurrence means the cancer has come back in the nearby lymph nodes. […] Signs and symptoms of regional recurrence may include a lump or swelling in the lymph nodes located: Under your arm. Near your collarbone. In the groove above your collarbone. In your neck. […] A distant (metastatic) recurrence means the cancer has traveled to distant parts of the body, most commonly the bones, liver and lungs. […] Signs and symptoms include: Persistent and worsening pain, such as chest, back or hip pain. Persistent cough. Difficulty breathing. Loss of appetite. Weight loss without trying. Severe headaches. Seizures.

• #32 Recognizing and Managing Recurrent Breast Cancer: Signs and Treatment Options

  https://aocancer.com/blog/recognizing-and-managing-recurrent-breast-cancer-signs-and-treatment-options

  If the cancer returns in the breast tissue, you may experience the following symptoms: Discharge from the nipple, New lump in the breast, Irregular firmness in the breast, Skin inflammation, Redness, Other skin changes. […] Cancer in the chest wall following a mastectomy (the surgical removal of one or both breasts) may have the following signs and symptoms: Nodules form on or under the skin of the chest wall, New thickening near the scar line of the mastectomy. […] Regional breast cancer typically includes a lump or swelling in lymph nodes located in the following areas: In your neck, Under your arm, Near or above your collarbone. […] Signs and symptoms associated with distant breast cancer recurrence typically include: Ongoing and worsening pain, such as the chest or hip, Sudden and unintentional weight loss, Persistent cough, Bone pain, Jaundice (yellowing of the skin or eyes), Difficulty breathing, Seizures.

• #33 Chest Wall Recurrence After Mastectomy: Symptoms and More

  https://www.verywellhealth.com/chest-wall-recurrence-430053

  A chest wall recurrence is when breast cancer returns after receiving treatment. A chest wall recurrence may involve skin, muscle, and fascia (a thin layer of connective tissue) beneath the site of the original breast tumor, as well as the lymph nodes. […] Symptoms may present differently and can vary greatly depending on where the cancer recurs and what type of treatments you have previously received. Always discuss any new or worrisome symptoms with your healthcare provider. […] A few examples of breast cancer chest wall recurrence symptoms are: A sore or lump felt in the breast/chest, A discomfort or a pulling sensation in the breast/chest, Thickened or swollen skin near surgical site, Changes to nipple appearance or discharge, Chronic chest pain and/or dry cough, Severe headache or vision problems.

• #34 Breast Cancer Recurrence: Symptoms & Risks | Baptist Health

  https://cd.baptisthealth.com/care-services/conditions-treatments/breast-cancer-recurrence

  Breast cancer recurrence is when the cancer comes back sometime after treatment. […] Symptoms of breast cancer recurrence are dependent on the location of the breast cancer. Depending on if it is local, regional, or distant recurrence the symptoms may vary. […] Local recurrence is cancer that returns to the same breast or chest area that the breast cancer originated in. […] Regional recurrence of breast cancer means that the cancer has returned near the original tumor in the lymph nodes, which are in the armpit or collarbone area. […] Distant recurrence is breast cancer that has spread from the primary cancer to other organs or tissue in the body. […] If the local recurrence happens after a mastectomy, signs and symptoms appearing on the chest wall may include: One or more painless nodules on or under the skin of your chest wall.

• #35 Breast Cancer Recurrence: Rates, Signs & Treatment

  https://my.clevelandclinic.org/health/diseases/8328-breast-cancer-recurrence

  Breast cancer recurrence is when cancer comes back after treatment. Recurrent breast cancer may develop where it started, or spread to nearby lymph nodes or to more distant areas of your body. […] Symptoms vary depending on where cancer started. For example, cancer that comes back in the same area as the original cancer (local cancer) causes different symptoms than regional cancer, which is breast cancer that’s spread to nearby lymph nodes. […] Local breast cancer recurrence may cause: Breast lumps or bumps on or under your chest. Nipple changes, such as flattening or nipple discharge. Swollen skin or skin that pulls near the lumpectomy site. Thickening on or near the surgical scar. Unusually firm breast tissue. […] Regional breast cancer recurrence may cause: Chronic chest pain. Difficulty swallowing. Pain, swelling or numbness in one arm or shoulder. Swollen lymph nodes in your armpit or in or around your collarbone area.

• #36 Types and Symptoms of Recurrence, Living with Breast Cancer, CBCN

  https://cbcn.ca/en/symptoms-recurrence

  Signs and symptoms of a regional breast cancer recurrence may look like: Chronic chest pain, Difficulty swallowing, Pain, swelling, or numbness in one arm or shoulder, Lump or swelling in the lymph nodes located: Under your arm, Near or above your collarbone, Near the breastbone, In your neck. […] Signs and symptoms of a distant breast cancer recurrence may look like: Bone pain or pain in the affected area that is persistent, worsens over time, and may be worse at night, Severe headaches, Numbness or weakness, Vision problems, Chronic dry cough, Difficulty breathing, Dizziness or balance problems, Seizures, Extreme fatigue, Loss of appetite, nausea, and weight loss.

• #37 Breast Cancer Recurrence: Causes, Symptoms, and Treatment | Breast Care Center Miami

  https://www.toplinemd.com/breast-care-center-of-miami/blog/breast-cancer-recurrence-causes-symptoms-and-treatment/

  Symptoms in the case of regional recurrence include the following: Stubborn chest pain, Numbness, swelling, and pain in one shoulder/arm, Swelling/lump in the underarm lymph nodes or around the breastbone or collarbone. […] The common symptoms of distant recurrence include: Stubborn and unyielding pain in the back, chest, or hip area, Troubled breathing and constant coughing, Weight loss and lack of appetite, Excruciating headaches, Seizures.

• #38 Breast Cancer Recurrence: Symptoms & Risks | Baptist Health

  https://cd.baptisthealth.com/care-services/conditions-treatments/breast-cancer-recurrence

  Signs or symptoms of regional recurrence may include: Chronic chest pain, Difficulty swallowing, Pain, swelling, or numbness in one arm or shoulder, Swollen lymph nodes under the arm or near the collarbone or breastbone. […] Distant (metastatic) recurrence means that the cancer has spread to distant organs or tissues in the body. Metastatic breast cancer usually spreads to the bones, lungs, brain, or liver. Symptoms include: Persistent and worsening pain in the chest, back, ribs, or hips (bone pain), Difficulty with breathing, Persistent cough, Dizziness or balance problems, Extreme fatigue, Unexplained weight loss, Loss of appetite or nausea, Persistent and worsening headaches, Vision problems, Seizure. […] Recurrent breast cancer is caused by cancer cells from the original tumor. The recurrence happens when the original cancer cells hide in nearby tissue or another part of the body and survive against the original cancer treatments. […] There are several treatment options for breast cancer recurrence. The treatment will depend on the cancer type, size, and location. There are some variations in treatment depending on whether the recurrence is local, regional, or distant.

• #39

  https://content.irisoncology.com/library/recurrent-breast-cancer

  Signs and symptoms of local recurrence on the chest wall after a mastectomy may include: One or more painless nodules on or under the skin of your chest wall. A new area of thickening along or near the mastectomy scar. […] A regional breast cancer recurrence means the cancer has come back in the nearby lymph nodes. […] Signs and symptoms of regional recurrence may include a lump or swelling in the lymph nodes located: Under your arm. Near your collarbone. In the groove above your collarbone. In your neck. […] A distant (metastatic) recurrence means the cancer has traveled to distant parts of the body, most commonly the bones, liver and lungs. […] Signs and symptoms include: Persistent and worsening pain, such as chest, back or hip pain. Persistent cough. Difficulty breathing. Loss of appetite. Weight loss without trying. Severe headaches. Seizures.

• #40 Breast Cancer Recurrence: Types, Symptoms and Risk

  https://www.cancercenter.com/cancer-types/breast-cancer/types/rare-breast-cancer-types/recurrent-breast-cancer

  Pay special attention to these symptoms, which could signal a breast cancer recurrence: Weight loss without trying, Headaches, bone pain or any new or different pain that the patient cant explain, Shortness of breath or wheezing, Seizures, Fatigue, Fever, chills or a cough that wont get better, Yellow tinge to skin and eyes (jaundice), Easy bruising or bleeding, Digestive issues, like nausea, vomiting, diarrhea, loss of appetite or trouble swallowing, Blood in the urine or stools, Any new lumps or areas of swelling. […] In general, the more time that goes by, the lower the risk of recurrence. Cancer is most likely to recur in the first two years after treatment, and once people get to five years of living cancer-free after treatment, its considered to be a significant milestone to be celebrated. Recurrence after that five year markrare, but possibleis called late recurrence. […] If the care team suspects a cancer recurrence, theyll recommend diagnostic tests, like lab tests, imaging or biopsies, both to be sure the cancer has come back and to get more information to guide treatment.

• #41 Types and Symptoms of Recurrence, Living with Breast Cancer, CBCN

  https://cbcn.ca/en/symptoms-recurrence

  Signs and symptoms of a regional breast cancer recurrence may look like: Chronic chest pain, Difficulty swallowing, Pain, swelling, or numbness in one arm or shoulder, Lump or swelling in the lymph nodes located: Under your arm, Near or above your collarbone, Near the breastbone, In your neck. […] Signs and symptoms of a distant breast cancer recurrence may look like: Bone pain or pain in the affected area that is persistent, worsens over time, and may be worse at night, Severe headaches, Numbness or weakness, Vision problems, Chronic dry cough, Difficulty breathing, Dizziness or balance problems, Seizures, Extreme fatigue, Loss of appetite, nausea, and weight loss.

• #42 How are Treatments Different for Recurrent Breast Cancer?

  https://www.cancercarebrevard.com/blog/how-are-treatments-different-for-recurrent-breast-cancer

  Regional recurrence may include a lump or swelling in lymph nodes in the neck, around the collarbone, or under the arm. […] A distant recurrence that develops in the bones, liver, or lungs can cause these symptoms: Pain that doesn’t go away or worsens, Severe headaches, Persistent cough, Breathing problems, Appetite loss, Weight loss, Seizures. […] Contact your breast cancer specialist right away for testing to confirm, or rule out, potential recurrent breast cancer.

• #43 Recurrent Breast Cancer: Signs, Symptoms, and Treatment Options

  https://www.compassoncology.com/blog/recurrent-breast-cancer-signs-symptoms-and-treatment-options

  Identifying the return of breast cancer involves recognizing the symptoms, which could look different based on where the cancer returns. Common signs include: […] Local Recurrence Symptoms: a new lump or thickening in the breast or chest wall, changes in breast shape or size, discharge from the nipple, and skin changes such as redness or dimpling. […] Regional Recurrence Symptoms: Swelling or lumps in the lymph nodes under the arm, near the collarbone, or in the neck. Pain or changes in the skin around these areas might also be observed. […] Distant Recurrence Symptoms: Persistent pain (especially in the bones), loss of appetite, unexplained weight loss, chronic cough, difficulty breathing, headaches, and seizures. […] If you experience any of these breast cancer symptoms, it’s important to consult your doctor right away for further investigation of what might be causing your symptoms.

• #44 Metastatic Breast Cancer Explained: Symptoms, Diagnosis & More

  https://www.nationalbreastcancer.org/metastatic-breast-cancer/

  Metastatic breast cancer (MBC) is Stage 4 breast cancer that has spread from the original location in the breast to other areas of the body. […] When breast cancer recurs, or returns, to another part of the body months or years after the initial breast cancer diagnosis and treatment (also referred to as distant recurrence), it is called metastatic breast cancer. […] The most common distant areas for invasive ductal breast cancer to spread to are the bones, lungs, liver, and brain. […] While early stage breast cancer may not have any signs or symptoms, advanced cancer such as metastatic breast cancer may have signs and symptoms that the patient is aware of. […] According to Johns Hopkins, people, especially those who have been treated for breast cancer, should watch for symptoms such as: Unusual or persistent back or neck pain (that is not explained by an injury or exercise), Pain in the bones, Unexplained shortness of breath, Profound fatigue or malaise (feeling generally unwell), Headache, Seizures, Mood changes, Difficulty with speech, Vision changes.

• #45 Stage 4 (IV) Breast Cancer: Survival Rates, Treatment & Prognosis

  https://www.nationalbreastcancer.org/breast-cancer-stage-4/

  After bones, the lungs are the second most common area of the body for breast cancer to spread to, affecting approximately 60% of Stage 4 breast cancer patients. […] Approximately 50% of individuals with Stage 4 breast cancer will develop liver metastases at some point. […] Brain metastasis occurs in approximately 10-15% of women with Stage 4 breast cancer. […] Not all Stage 4 breast cancer has observable signs or symptoms. But if breast cancer has spread to the bones, the following signs and symptoms may be felt: Severe, progressive bone pain, particularly in the spine, ribs, pelvis, or long bones in the arms and legs; Swelling of joints within the skeletal system; Weak or fragile bones, not as a result of osteoporosis; Weakness in the arms or legs; High levels of calcium in the blood (hypercalcemia).

• #46 Metastatic Breast Cancer Explained: Symptoms, Diagnosis & More

  https://www.nationalbreastcancer.org/metastatic-breast-cancer/

  Metastatic breast cancer may have additional, specific symptoms, depending on the location of the metastases. […] Metastatic breast cancer with bone metastasis is when breast cancer has spread from the original location in the breast to the bones. […] Symptoms of metastatic breast cancer in the bones can include: Severe, progressive bone pain, particularly in the spine, ribs, pelvis, or long bones in the arms and legs. […] Breast cancer metastasis to the lungs is when breast cancer has spread from the original location in the breast to one or both lungs. […] Symptoms of metastatic breast cancer in the lungs can include: Chronic cough, Inability to take a full breath (shortness of breath), Pain or discomfort in the chest area, Difficulty in catching one’s breath after physical exertion.

• #47 The Likelihood of Recurrence | Breast Cancer Trials

  https://www.breastcancertrials.org.au/breast-cancer-recurrence/?srsltid=AfmBOopg68yaCOPLHnnNv4HhwqmuEw70-A_aKFsjlgW40ulIQ6vSuf5T

  Breast cancer recurrence means that the cancer was diagnosed when limited to the breast and/or armpit lymph nodes, then treated, and at some time later has come back. […] Breast cancer recurrence occurs in three main ways: Local recurrence: the breast cancer that was previously treated returns within the breast or armpit lymph nodes. […] Many breast cancer recurrences are detected in the five years after diagnosis, especially after triple negative breast cancer. However, recurrence can occur more than 20 years after the first diagnosis. […] If you have a local recurrence or new primary breast cancer, you may find symptoms similar to an initial breast cancer. These include: A new lump in the breast, armpit area or around the collarbone. […] If your breast cancer has spread to other parts to the body, known as distant recurrence, there are a number of possible symptoms, including: Fatigue, Breathlessness, Pain in your bones, Unexpected weight loss or change in appetite, Severe or ongoing headaches, Nausea. […] However, symptoms will vary depending on where the secondary cancer presents, and some primary and secondary cancers may not present any obvious symptoms. Sometimes breast cancer recurrence is identified on a scan or blood test that was done for a reason other than the cancer itself.

• #48 Stage 4 (IV) Breast Cancer: Survival Rates, Treatment & Prognosis

  https://www.nationalbreastcancer.org/breast-cancer-stage-4/

  After bones, the lungs are the second most common area of the body for breast cancer to spread to, affecting approximately 60% of Stage 4 breast cancer patients. […] Approximately 50% of individuals with Stage 4 breast cancer will develop liver metastases at some point. […] Brain metastasis occurs in approximately 10-15% of women with Stage 4 breast cancer. […] Not all Stage 4 breast cancer has observable signs or symptoms. But if breast cancer has spread to the bones, the following signs and symptoms may be felt: Severe, progressive bone pain, particularly in the spine, ribs, pelvis, or long bones in the arms and legs; Swelling of joints within the skeletal system; Weak or fragile bones, not as a result of osteoporosis; Weakness in the arms or legs; High levels of calcium in the blood (hypercalcemia).

• #49 Metastatic Breast Cancer Explained: Symptoms, Diagnosis & More

  https://www.nationalbreastcancer.org/metastatic-breast-cancer/

  Metastatic breast cancer may have additional, specific symptoms, depending on the location of the metastases. […] Metastatic breast cancer with bone metastasis is when breast cancer has spread from the original location in the breast to the bones. […] Symptoms of metastatic breast cancer in the bones can include: Severe, progressive bone pain, particularly in the spine, ribs, pelvis, or long bones in the arms and legs. […] Breast cancer metastasis to the lungs is when breast cancer has spread from the original location in the breast to one or both lungs. […] Symptoms of metastatic breast cancer in the lungs can include: Chronic cough, Inability to take a full breath (shortness of breath), Pain or discomfort in the chest area, Difficulty in catching one’s breath after physical exertion.

• #50 Symptoms of secondary breast cancer | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/breast-cancer/secondary/symptoms

  You may have any of these symptoms if your cancer has spread into the lungs: a cough that doesn’t go away, shortness of breath, ongoing chest infections, chest pain, coughing up blood, a build up of fluid between the chest wall and the lung (a pleural effusion). […] Cancer that has spread to the brain can cause different symptoms depending on where in the brain it spreads to. You might have any of these symptoms: headaches, weakness or numbness in your limbs, memory problems, behaving in a way that is unusual for you, feeling or being sick, seizures (fits), changes to your eyesight such as loss of sight (vision), confusion and difficulty understanding, difficulty speaking. […] When breast cancer is advanced it can’t be cured. But treatment can control it for some time and help to relieve symptoms.

• #51 Stage 4 (IV) Breast Cancer: Survival Rates, Treatment & Prognosis

  https://www.nationalbreastcancer.org/breast-cancer-stage-4/

  Lung metastasis may not produce signs or symptoms. But if signs and symptoms are present, the following may indicate metastasis to the lungs: Chronic cough; Shortness of breath, particularly after physical exertion; Pain or discomfort in the chest area. […] Stage 4 breast cancer in the liver rarely produces symptoms. But if symptoms do occur, they can include: Jaundice (yellowing of the skin and whites of the eyes); Itchy skin or rash; High liver enzyme levels determined through a blood test; Abdominal pain, particularly on the right side; Weakness; Loss of appetite; Nausea and vomiting; Light gray stool color; Weight loss. […] Metastasis of Stage 4 breast cancer in the brain may cause a variety of symptoms: Persistent and progressively worsening headaches or pressure in the head; Memory loss; Vision disturbances (blurred vision, double vision, loss of vision, etc.); Slurred speech; Dizziness or balance problems; Weakness or paralysis on one side of the body; Numbness or tingling in the extremities; Nausea or vomiting; Seizures or stroke; Mood, personality, or behavioral changes; Impaired judgment.

• #52 Metastatic Breast Cancer Explained: Symptoms, Diagnosis & More

  https://www.nationalbreastcancer.org/metastatic-breast-cancer/

  Breast cancer metastasis in the liver is when breast cancer has spread from the original location in the breast to the liver. […] Symptoms of metastatic breast cancer in the liver can include: Jaundice, Itchy skin or rash, Abnormally high enzymes in the liver, Abdominal pain, particularly in the right side, Weakness, Loss of appetite, Nausea and vomiting, Stool color turning light gray. […] Breast cancer metastasis in the brain means that breast cancer has spread from the original location in the breast to the brain. […] Symptoms of metastatic breast cancer to the brain can include: Persistent, progressively worsening headaches or pressure in the head, Memory loss, Vision disturbances, Slurred speech, Dizziness, Balance problems, Weakness or paralysis on one side of the body, Numbness or tingling in the extremities, Nausea or vomiting, Seizures, Mood, personality, or behavioral changes.

• #53 Symptoms of secondary breast cancer | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/breast-cancer/secondary/symptoms

  Secondary breast cancer means that a cancer that began in the breast has spread to another part of the body. It is also called advanced or metastatic breast cancer. […] The general symptoms of secondary breast cancer include: tiredness (fatigue), difficulty sleeping, loss of appetite, unexplained weight loss, feeling or being sick, pain. […] Bone pain is the most common symptom of breast cancer that has spread to the bones. Your bones might also become weaker and more likely to break (fracture). […] Back pain is usually the first symptom of spinal cord compression. […] You may have any of the following symptoms if cancer has spread to your liver: tiredness, pain on the right side of your tummy (abdomen) where the liver is, feeling sick (nausea), loss of appetite, a swollen abdomen, yellowing of the skin and whites of the eyes (jaundice), itchy skin.

• #54 Stage 4 (IV) Breast Cancer: Survival Rates, Treatment & Prognosis

  https://www.nationalbreastcancer.org/breast-cancer-stage-4/

  Lung metastasis may not produce signs or symptoms. But if signs and symptoms are present, the following may indicate metastasis to the lungs: Chronic cough; Shortness of breath, particularly after physical exertion; Pain or discomfort in the chest area. […] Stage 4 breast cancer in the liver rarely produces symptoms. But if symptoms do occur, they can include: Jaundice (yellowing of the skin and whites of the eyes); Itchy skin or rash; High liver enzyme levels determined through a blood test; Abdominal pain, particularly on the right side; Weakness; Loss of appetite; Nausea and vomiting; Light gray stool color; Weight loss. […] Metastasis of Stage 4 breast cancer in the brain may cause a variety of symptoms: Persistent and progressively worsening headaches or pressure in the head; Memory loss; Vision disturbances (blurred vision, double vision, loss of vision, etc.); Slurred speech; Dizziness or balance problems; Weakness or paralysis on one side of the body; Numbness or tingling in the extremities; Nausea or vomiting; Seizures or stroke; Mood, personality, or behavioral changes; Impaired judgment.

• #55 Metastatic Breast Cancer Explained: Symptoms, Diagnosis & More

  https://www.nationalbreastcancer.org/metastatic-breast-cancer/

  Breast cancer metastasis in the liver is when breast cancer has spread from the original location in the breast to the liver. […] Symptoms of metastatic breast cancer in the liver can include: Jaundice, Itchy skin or rash, Abnormally high enzymes in the liver, Abdominal pain, particularly in the right side, Weakness, Loss of appetite, Nausea and vomiting, Stool color turning light gray. […] Breast cancer metastasis in the brain means that breast cancer has spread from the original location in the breast to the brain. […] Symptoms of metastatic breast cancer to the brain can include: Persistent, progressively worsening headaches or pressure in the head, Memory loss, Vision disturbances, Slurred speech, Dizziness, Balance problems, Weakness or paralysis on one side of the body, Numbness or tingling in the extremities, Nausea or vomiting, Seizures, Mood, personality, or behavioral changes.

• #56 Breast cancer recurrence symptoms and signs | LBBC

  https://www.lbbc.org/about-breast-cancer/symptoms/signs-recurrence

  You may also have symptoms that are not specific to a body part, such as extreme tiredness or loss of appetite. […] The most common place that breast cancer spreads is to the bones. […] Breast cancer in the liver can cause these general symptoms: Extreme tiredness, Weight loss, Discomfort. […] Breast cancer that spreads to the lungs can cause breathing problems such as: Dry cough, Shortness of breath, Chest pain. […] When breast cancer spreads to the brain it can cause: Intense headaches, Headaches that don’t go away, Nausea, Dizziness, Seizures.

• #57 The lingering mysteries of metastatic recurrence in breast cancer | British Journal of Cancer

  https://www.nature.com/articles/s41416-020-01161-4

  Despite being the hallmark of cancer that is responsible for the highest number of deaths, very little is known about the biology of metastasis. […] In the case of breast cancer, metastatic relapse can occur months to decades after initial diagnosis and treatment. […] Metastatic recurrence is a significant problem in patients with breast cancer, the most frequently diagnosed malignancy and the second leading cause of cancer-related death among women worldwide. […] 2030% of patients with early breast cancer still die of metastatic disease. […] Protracted intervals between diagnosis and recurrence have been proposed to be the result of tumour dormancy, whereby clinically undetectable minimal residual disease (MRD) can lie asymptomatic for many years to decades. […] Thus, given its systemic nature and inevitable resistance to therapy, metastatic recurrence is largely incurable and remains the foremost concern for cancer patients and their caregivers.

• #58 Signs of Breast Cancer Recurrence

  https://www.healthline.com/health/breast-cancer/signs-of-recurrence

  In general, triple-negative breast cancers and HER2-amplified breast cancers are most likely to recur compared to luminal A breast cancers (estrogen receptor-positive, progesterone receptor-positive, and HER2-negative breast cancers), which are least likely to return. […] More advanced breast cancers that have nodal involvement are more likely to recur than early stage breast cancers. […] The chances of a recurrence are also dependent upon age. An older woman with an early stage hormone-receptor breast cancer who undergoes breast conservation plus radiation and anti-estrogen therapy will have a recurrence rate of about 2% in 10 years. This is very different than a young woman with advanced triple-negative breast cancer their chance of recurrence is significantly higher. […] Typically, triple-negative and HER2-positive breast cancers are much more likely to return within 5 years of diagnosis, if they are going to return at all.

• #59 Breast cancer recurrence rates: Types and outlook

  https://www.medicalnewstoday.com/articles/breast-cancer-types-recurrence-rates

  The risk of breast cancer recurrence varies depending on the type of breast cancer, the stage of the cancer at diagnosis, and the persons age and health. Inflammatory breast cancer and triple-negative breast cancer have the highest recurrence rates. […] After treatment, some people may experience breast cancer recurrence, which is the return of cancer cells in the breast or nearby areas. […] Breast cancer recurrence is when breast cancer returns or recurs after treatment. It can occur in the same breast, lymph nodes under the arm, or other parts of the body. […] Most people with breast cancer will not experience a recurrence. However, the risk of recurrence still exists for some individuals even years after their initial diagnosis and treatment. […] All types of breast cancer can recur, but aggressive subtypes, such as inflammatory breast cancer (IBC) and triple-negative breast cancer (TNBC), are more likely to return.

• #60 Signs of Breast Cancer Recurrence

  https://www.healthline.com/health/breast-cancer/signs-of-recurrence

  In general, triple-negative breast cancers and HER2-amplified breast cancers are most likely to recur compared to luminal A breast cancers (estrogen receptor-positive, progesterone receptor-positive, and HER2-negative breast cancers), which are least likely to return. […] More advanced breast cancers that have nodal involvement are more likely to recur than early stage breast cancers. […] The chances of a recurrence are also dependent upon age. An older woman with an early stage hormone-receptor breast cancer who undergoes breast conservation plus radiation and anti-estrogen therapy will have a recurrence rate of about 2% in 10 years. This is very different than a young woman with advanced triple-negative breast cancer their chance of recurrence is significantly higher. […] Typically, triple-negative and HER2-positive breast cancers are much more likely to return within 5 years of diagnosis, if they are going to return at all.

• #61 Recurrent breast cancer – Hancock Health

  https://www.hancockhealth.org/mayo-health-library/recurrent-breast-cancer/

  For breast cancer survivors, factors that increase the risk of a recurrence include: Lymph node involvement. Finding cancer in nearby lymph nodes at the time of your original diagnosis increases your risk of the cancer coming back. Larger tumor size. People with larger tumors have a greater risk of recurrent breast cancer. Positive or close tumor margins. […] Lack of radiation treatment following a lumpectomy. Most people who choose a lumpectomy (wide local excision) for breast cancer undergo breast radiation therapy to reduce the risk of recurrence. […] Younger age. Younger people, particularly those under age 35 at the time of their original breast cancer diagnosis, face a higher risk of recurrent breast cancer. […] Inflammatory breast cancer. People with inflammatory breast cancer have a higher risk of local recurrence.

• #62 Recurrent breast cancer – Hancock Health

  https://www.hancockhealth.org/mayo-health-library/recurrent-breast-cancer/

  For breast cancer survivors, factors that increase the risk of a recurrence include: Lymph node involvement. Finding cancer in nearby lymph nodes at the time of your original diagnosis increases your risk of the cancer coming back. Larger tumor size. People with larger tumors have a greater risk of recurrent breast cancer. Positive or close tumor margins. […] Lack of radiation treatment following a lumpectomy. Most people who choose a lumpectomy (wide local excision) for breast cancer undergo breast radiation therapy to reduce the risk of recurrence. […] Younger age. Younger people, particularly those under age 35 at the time of their original breast cancer diagnosis, face a higher risk of recurrent breast cancer. […] Inflammatory breast cancer. People with inflammatory breast cancer have a higher risk of local recurrence.

• #63 Recurrent breast cancer – Hancock Health

  https://www.hancockhealth.org/mayo-health-library/recurrent-breast-cancer/

  Lack of endocrine therapy for hormone receptor-positive breast cancer. In people who have a certain type of breast cancer, not receiving endocrine therapy can raise their risk of recurrence. […] Cancer cells with certain characteristics. If you had triple negative breast cancer, you may have an increased risk of breast cancer recurrence. […] Obesity. Having a higher body mass index increases your risk of recurrence. […] Strategies that have been linked to a reduced risk of breast cancer recurrence include: Hormone therapy. Taking hormone therapy after your initial treatment may reduce the risk of recurrence if you have hormone receptor positive breast cancer. […] Chemotherapy. For people with breast cancer who have an increased risk of cancer recurrence, chemotherapy has been shown to decrease the chance that cancer will recur, and those who receive chemotherapy live longer.

• #64 Breast Cancer Recurrence – Symptoms & Preventions

  https://cancerconsultindia.com/blog/breast-cancer-recurrence-symptoms-preventions

  Inflammatory breast cancer and triple-negative breast cancer are the most typical cancer type that recurs. […] Types of recurrent breast cancer: Local recurrence: When cancer returns to the same part of the breast as the initial diagnosis, that is called a local recurrence. Regional recurrence: This type gets diagnosed when breast cancer occurs in nearby lymph nodes and the chest wall. Distant recurrence: Also called metastatic breast cancer, this type occurs when cancer cells travel away from the original tumor in the breast to other parts of the body through the lymphatic system or bloodstream. […] The risk of recurrence is unique to each person diagnosed with early-stage breast cancer by breast Cancer Treatment in Noida. For survivors, factors of high risk of a recurrence include: Lymph node involvement. Larger tumor size. Positive tumor margins. Younger age. Inflammatory breast cancer. Lack of endocrine therapy for receptor-positive hormone breast cancer. Cancer cells with specific characteristics. Obesity. Cancer stage.

• #65 Signs of Breast Cancer Recurrence

  https://www.healthline.com/health/breast-cancer/signs-of-recurrence

  In general, triple-negative breast cancers and HER2-amplified breast cancers are most likely to recur compared to luminal A breast cancers (estrogen receptor-positive, progesterone receptor-positive, and HER2-negative breast cancers), which are least likely to return. […] More advanced breast cancers that have nodal involvement are more likely to recur than early stage breast cancers. […] The chances of a recurrence are also dependent upon age. An older woman with an early stage hormone-receptor breast cancer who undergoes breast conservation plus radiation and anti-estrogen therapy will have a recurrence rate of about 2% in 10 years. This is very different than a young woman with advanced triple-negative breast cancer their chance of recurrence is significantly higher. […] Typically, triple-negative and HER2-positive breast cancers are much more likely to return within 5 years of diagnosis, if they are going to return at all.

• #66 Signs of Breast Cancer Recurrence

  https://www.healthline.com/health/breast-cancer/signs-of-recurrence

  If a woman has a luminal A tumor, then it can recur many years later. For example, we sometimes see a recurrence of estrogen-sensitive breast cancers 10-plus years after initial diagnosis. […] A locally advanced tumor is more likely to recur sooner than a less aggressive, smaller tumor. […] Young women with more aggressive tumors and more advanced stages (triple-negative breast cancer or HER2-positive breast cancers) have a much higher chance of recurrence. […] However, in elderly women with very early stages of breast cancer, a very small percentage have a breast cancer recurrence often less than 2% in 10 years. […] A woman who treated her initial breast cancer with a lumpectomy may feel a palpable mass or lump, have nipple changes or bloody nipple discharge, or experience skin changes. This can be a sign that the breast cancer has returned.

• #67 Breast Cancer Recurrence: Types, Symptoms and Risk

  https://www.cancercenter.com/cancer-types/breast-cancer/types/rare-breast-cancer-types/recurrent-breast-cancer

  Pay special attention to these symptoms, which could signal a breast cancer recurrence: Weight loss without trying, Headaches, bone pain or any new or different pain that the patient cant explain, Shortness of breath or wheezing, Seizures, Fatigue, Fever, chills or a cough that wont get better, Yellow tinge to skin and eyes (jaundice), Easy bruising or bleeding, Digestive issues, like nausea, vomiting, diarrhea, loss of appetite or trouble swallowing, Blood in the urine or stools, Any new lumps or areas of swelling. […] In general, the more time that goes by, the lower the risk of recurrence. Cancer is most likely to recur in the first two years after treatment, and once people get to five years of living cancer-free after treatment, its considered to be a significant milestone to be celebrated. Recurrence after that five year markrare, but possibleis called late recurrence. […] If the care team suspects a cancer recurrence, theyll recommend diagnostic tests, like lab tests, imaging or biopsies, both to be sure the cancer has come back and to get more information to guide treatment.

• #68 Recurrent Breast Cancer – Causes, Symptoms and Treatment | Apollo Hospitals

  https://www.apollohospitals.com/diseases-and-conditions/recurrent-breast-cancer-causes-symptoms-and-treatment

  A distant recurrence means the cancer has spread to distant parts of the body, causing: Persistent chest, back or hip pain, Cough and breathlessness, Loss of appetite, Weight loss, Severe headaches, Seizures. […] After your breast cancer treatment is over, your doctor will probably arrange a follow-up examination schedule for you. They will examine for symptoms or signs of recurrent breast cancer during these examinations. […] It may be harder to learn about recurrent breast cancer than to handle the initial diagnosis. But recurring breast cancer is not hopeless. Treatment may remove recurrent local, regional, or distant breast cancer. Even if the cure is not possible, treatment can control the disease for a long time. […] Among patients who remained recurrence-free after five years of endocrine treatment, those with initial large tumors and cancer progressed to four or more lymph nodes had the most significant risk of recurrence. […] Yes, women exposed to stress have a greater chance of recurrent breast cancer than those who are not.

• #69 Breast cancer recurrence rates: Types and outlook

  https://www.medicalnewstoday.com/articles/breast-cancer-types-recurrence-rates

  The average time for breast cancer recurrence varies depending on the breast cancer subtype. For example, most local breast cancer recurrence occurs within the first 5 years after diagnosis. […] However, people with TNBC have a higher risk of recurrence, and their cancer may return as early as 2.6 years after diagnosis. […] The outlook for recurrent breast cancer is generally better than it used to be. With advances in treatment, many people with recurrent breast cancer can live long and healthy lives. […] The relative 5-year survival rate for people with recurrent breast cancer is about 25%. This means that 25 out of 100 people with recurrent breast cancer will survive for at least 5 years after their diagnosis. However, this number can vary depending on the factors mentioned above. […] Anyone diagnosed with breast cancer is at risk of recurrence, but most people will not experience a recurrence. The risk of recurrence is higher for those with IBC, TNBC, or other risk factors.

• #70 Risks, Symptoms, and Treatments for Breast Cancer Recurrence – Ezra

  https://ezra.com/blog/breast-cancer-recurrence

  Breast cancer that comes back within five years of diagnosis and initial treatment is called early recurrence. Breast cancer that returns more than five years after diagnosis and initial treatment is called late recurrence. […] A bilateral mastectomy, or surgical removal of both breasts, significantly reduces your chances of breast cancer relapse. However, there is still a minimal chance that residual breast tissue or cancer cells could recur on the chest wall. […] Local breast cancer recurrence is when cancer comes back in the same area that the first tumor was found. […] Regional recurrence is when cancer reappears in the lymph nodes in the armpit or collarbone area near where the tumor was initially diagnosed. […] Distant breast cancer recurrence is when breast cancer has spread (metastasis) to another organ or part of your body, such as your lungs, bones, or brain. Though rare, distance recurrence can also occur in the opposite breast. […] You can assess your risk of cancer or cancer recurrence by taking ezras know-your-risk quiz, which evaluates questions about your lifestyle and medical history.

• #71 Recognizing and Managing Recurrent Breast Cancer: Signs and Treatment Options

  https://aocancer.com/blog/recognizing-and-managing-recurrent-breast-cancer-signs-and-treatment-options

  Breast cancer is often successfully treated, especially when it is detected early. That fact remains, however, breast cancer returns for some patients after the initial treatment plan is complete. This is what is known as recurrent breast cancer. […] Recurrent breast cancer is caused by cancer cells that were not completely destroyed during the initial treatment process. Those cells can lay dormant (inactive) for several months, or years before they start to grow again. […] While breast cancer recurrence is most common in the first five years after treatment is complete, it can recur months, or many years, following treatment. […] The signs and symptoms of recurrent breast cancer can vary from patient to patient and may look different based on where the cancer comes back. Its important that you follow your doctors recommended follow-up imaging schedule to look for cancer that cant be detected by feeling the breast.

• #72 The lingering mysteries of metastatic recurrence in breast cancer | British Journal of Cancer

  https://www.nature.com/articles/s41416-020-01161-4

  This range in recurrence intervals is likely to reflect, at least in part, tumour cell dissemination, the balance between cell-extrinsic and cell-intrinsic factors in the metastatic environment and the putative dormancy of metastatic cells at distant sites. […] Metastatic relapse is attributed to the outgrowth of cancer cells that have escaped from the primary tumour and take up residence in secondary sites. […] The process whereby DTCs transform a localised cancer into a systemic disease is called the metastatic cascade. […] The first step of the metastatic cascade refers to the ability of cancer cells to escape from the primary tumour. […] The second step of the metastatic cascade refers to DTC ability to invade adjacent local tissues. […] The third step of the cascade is known as intravasation.

• #73 The lingering mysteries of metastatic recurrence in breast cancer | British Journal of Cancer

  https://www.nature.com/articles/s41416-020-01161-4

  This range in recurrence intervals is likely to reflect, at least in part, tumour cell dissemination, the balance between cell-extrinsic and cell-intrinsic factors in the metastatic environment and the putative dormancy of metastatic cells at distant sites. […] Metastatic relapse is attributed to the outgrowth of cancer cells that have escaped from the primary tumour and take up residence in secondary sites. […] The process whereby DTCs transform a localised cancer into a systemic disease is called the metastatic cascade. […] The first step of the metastatic cascade refers to the ability of cancer cells to escape from the primary tumour. […] The second step of the metastatic cascade refers to DTC ability to invade adjacent local tissues. […] The third step of the cascade is known as intravasation.

• #74 The lingering mysteries of metastatic recurrence in breast cancer | British Journal of Cancer

  https://www.nature.com/articles/s41416-020-01161-4

  The fifth step of the metastatic cascade is metastatic seeding, a process that results in the docking of extravasated DTCs in distant foreign sites. […] The sixth step of the cascade is metastatic outgrowth, cell death and dormancy are three distinct fates that DTCs can undergo through various mechanisms. […] Tumour dormancy is generally defined as a prolonged state of asymptomatic micrometastatic disease. […] During this latent period, patients are considered to be disease-free due to the lack of any symptoms of illness and because they have no detectable neoplasms by clinical imaging. […] However, its nature appears to be reversible, as myriad mechanisms have been shown to induce a switch to reawaken indolent DTCs. […] The presence of non-proliferative CTCs in the blood of clinically disease-free breast cancer patients is consistent with a tumour-mass dormancy model, as replenishment of CTCs could be indicative of the presence of replicating reservoirs of disease somewhere in the body.

• #75 News & Articles

  https://www.parkwaycancercentre.com/sg/news-events/news-articles/news-articles-details/need-to-know-about-breast-cancer-recurrence

  Just like garden weeds that grow back stubbornly if they were not completely removed, breast cancer cells may flourish and cause breast cancer to recur under the right environment within the body. […] Breast cancer may return despite the best care and treatment. When this happens, it is called a recurrence or relapse. A relapse may occur when some of the original cancer cells survive the initial treatment, or when cancer cells spread to other parts of the body while being undetected. […] Micrometastatic cancer cells that linger in the body may cause cancer recurrence further down the road. […] When a patient experiences a breast cancer relapse, it usually means that the disease has progressed into an advanced, incurable stage. That is why treating breast cancer early and thoroughly is important to prevent it from recurring.

• #76 Recurrent Breast Cancer: Causes, Symptoms, and Treatments | SELF

  https://www.self.com/story/recurrent-breast-cancer

  Signs and symptoms include: Persistent and worsening pain, such as chest or bone pain, Persistent cough, Difficulty breathing, Loss of appetite, Weight loss, Severe headaches, Seizures. […] Recurrent breast cancer occurs when cells that were part of your original breast cancer break away from the original tumor and hide nearby in the breast or in another part of your body. Later, these cells begin growing again. […] The chemotherapy, radiation, or hormone therapy you may have received after your first breast cancer diagnosis was intended to kill any cancer cells that may have remained after surgery. But sometimes these treatments aren’t able to kill all of the cancer cells. […] Sometimes cancer cells may be dormant for years without causing harm. Then something happens that activates the cells, so they grow and spread to other parts of the body. It’s not clear why this occurs.

• #77 How are Treatments Different for Recurrent Breast Cancer?

  https://www.cancercarebrevard.com/blog/how-are-treatments-different-for-recurrent-breast-cancer

  Regional recurrence may include a lump or swelling in lymph nodes in the neck, around the collarbone, or under the arm. […] A distant recurrence that develops in the bones, liver, or lungs can cause these symptoms: Pain that doesn’t go away or worsens, Severe headaches, Persistent cough, Breathing problems, Appetite loss, Weight loss, Seizures. […] Contact your breast cancer specialist right away for testing to confirm, or rule out, potential recurrent breast cancer.

• #78 Breast Cancer Recurrence | Breast Cancer Surgery Melbourne, VIC

  https://www.melbournebreastcancersurgery.com.au/breast-cancer-recurrence.html

  When breast cancer spreads to lymph nodes it has essentially declared its intent to metastasize. Breast cancer reaching the lymph nodes is in effect a declaration that its working to spread further. […] When breast cancer spreads it is still breast cancer. If you were to take a sample of the cancer in these locations and look at it under the microscope, the appearance would be of cancerous breast cells, not bone, liver, or lung cells. Thus, for example, breast cancer that has spread to the bones is not called bone cancer, but rather breast cancer metastatic to the bones. […] Breast cancer recurrence means that the cancer was diagnosed when limited to the breast and/or armpit lymph nodes, then treated, and at some time later has come back. […] Distant or systemic recurrence or metastasis is much more serious than local recurrence and is synonymous with stage 4 disease. For breast cancer patients, the most common areas of spread are the bone, liver, lungs and brain.

• #79 Breast Cancer Treatment – NCI

  https://www.cancer.gov/types/breast/patient/breast-treatment-pdq

  In inflammatory breast cancer, cancer has spread to the skin of the breast and the breast looks red and swollen and feels warm. […] The metastatic tumor is the same type of cancer as the primary tumor. For example, if breast cancer spreads to the bone, the cancer cells in the bone are actually breast cancer cells. The disease is metastatic breast cancer, not bone cancer.

• #80 Breast cancer recurrence symptoms | Breast Cancer Now

  https://breastcancernow.org/about-breast-cancer/diagnosis/breast-cancer-recurrence/breast-cancer-recurrence-symptoms

  Most breast cancers dont come back after treatment, but its very common to worry about breast cancer returning. […] If breast cancer does come back, its known as recurrence. […] Its important to know what signs and symptoms to look out for. […] Be aware of any changes to your breast or chest area. […] If youve had breast-conserving surgery, the cancer could come back in the remaining breast tissue. […] If youve had a mastectomy, the cancer could come back in the chest wall or in the skin. […] Sometimes breast cancer cells can spread from the breast to other parts of the body. This is known as secondary (metastatic) breast cancer. […] Each persons risk of breast cancer recurrence is different and depends on many factors, such as the size, type, grade and features of the cancer and whether the lymph nodes were affected.

• #81 Survival and Risk of Recurrence – Susan G. Komen®

  https://www.komen.org/breast-cancer/treatment/recurrence/survival-and-risk-of-recurrence/

  Everyone whos had breast cancer is at risk of recurrence (return of breast cancer). However, most people diagnosed with breast cancer will never have a recurrence. […] If you have a breast cancer recurrence, its not your fault. You did nothing to cause it. […] Local recurrence is the return of cancer to the breast, chest wall or nearby lymph nodes after treatment. Most local recurrences occurs within the first 5 years after diagnosis. If you have a local recurrence, youll need more treatment. […] Distant recurrence occurs when cancer spreads beyond the breast and nearby lymph nodes to other organs such as the bones, liver, lungs or brain. This is also called metastatic, stage IV or advanced breast cancer. […] For women with early breast cancer who have a lumpectomy plus radiation therapy, the risk of local recurrence depends on tumor characteristics, including biomarkers (such as hormone receptor status and HER2 status).

• #82 Breast Cancer Recurrence: Types, Rates, and More

  https://www.healthline.com/health/breast-cancer/what-type-breast-cancer-has-the-highest-recurrence-rate

  Aggressive, hard-to-treat breast cancers, such as inflammatory breast cancer (IBC) and triple-negative breast cancer (TNBC), are the types most likely to recur. […] Fast-growing cancers and cancers that were diagnosed at an advanced stage, are more likely to return. […] The two types of breast cancer most likely to recur are inflammatory breast cancer (IBC) and triple-negative breast cancer (TNBC). […] The symptoms of breast cancer recurrence depend on where the breast cancer recurs, as noted in this table: […] Although all types of breast cancer can recur after treatment, the two types of breast cancer that are most likely to come back are inflammatory breast cancer (IBC) and triple-negative breast cancer (TNBC). […] Yes. The risk of breast recurrence is highest in the first 2 years after you receive the initial diagnosis. The risk of recurrence decreases steadily as time passes.

• #83 What is inflammatory breast cancer (IBC)? | MD Anderson Cancer Center

  https://www.mdanderson.org/cancerwise/9-questions-about-inflammatory-breast-cancer–answered.h00-159306990.html

  Inflammatory breast cancer has specific features that drive progression, resistance and the migration of cancer cells, so it has a high rate of spreading and recurrence. Its very aggressive. […] The best way to reduce your chances of recurrence is to have the key therapies in the right order from the very beginning. That means systemic therapies first, followed by a modified radical mastectomy, and then comprehensive post-mastectomy radiation tailored to the original site of the disease. That also means taking advantage of any adjuvant therapies that may be offered. […] Inflammatory breast cancer is not a disease for diluting therapies or using less rigorous methods to try to reduce side effects. So, you want to avoid things like skin-sparing mastectomies, sentinel lymph node biopsies, and immediate reconstructions. With inflammatory breast cancer, the only role for non-guideline-based care is through a clinical trial.

• #84 Breast Cancer: Symptoms, Risk Factors & Treatments | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/breast-cancer.html

  A HER2-positive diagnosis was at one time associated with a higher risk of recurrence. Recent treatment advances, particularly with targeted therapies, have made the disease more curable in its early stages. They have also extended the survival period for patients whose cancer metastasized, or has spread beyond the breast and nearby lymph nodes. […] Most cases of advanced breast cancer are not considered curable. Instead, they are treated like a chronic illness. The goal of care is to prolong life and maintain the patients quality of life. With emerging therapies and treatments, many metastatic breast cancer patients can live well for years.

• #85 Survival and Risk of Recurrence – Susan G. Komen®

  https://www.komen.org/breast-cancer/treatment/recurrence/survival-and-risk-of-recurrence/

  With a mastectomy, the best predictor of local breast cancer recurrence is whether the axillary lymph nodes (the lymph nodes in the underarm area) contain cancer. The risk of local recurrence is usually higher when there are more axillary lymph nodes with cancer than when there are few or no nodes with cancer.

• #86 What’s the Risk of Breast Cancer Recurrence After Mastectomy? 11 Symptoms To Watch For | MyBCTeam

  https://www.mybcteam.com/resources/whats-the-risk-of-breast-cancer-recurrence-after-mastectomy-symptoms-to-watch-for

  After completing breast cancer treatment, you and your loved ones might worry about the possibility of the cancer returning, known as recurrence. Breast cancer can recur (return) if treatment doesn’t eliminate all cancer cells. Even after a double mastectomy a surgery that removes all breast tissue from both breasts there is still a possibility of recurrence. […] About 5 in every 100 women who undergo a mastectomy for breast cancer will experience a local recurrence within 10 years of their initial diagnosis. […] About 5 in every 100 women who undergo a mastectomy for breast cancer experience a local recurrence meaning the cancer returns in the chest area within 10 years of their initial diagnosis. […] The chance of recurrence is further influenced by whether the cancer was found in nearby lymph nodes and the type of follow-up treatments received. If no cancer is detected in the lymph nodes, the risk of recurrence is about 6 percent within five years after a mastectomy. If cancer is found in nearby lymph nodes, the risk or recurrence increases to around 25 percent.

• #87 When Breast Cancer Comes Back

  https://www.webmd.com/breast-cancer/breast-cancer-comes-back

  Distant: This is what doctors call metastatic cancer or stage IV breast cancer. Here, the cancer shows up far away from the original tumor in places like the bones, lungs, brain, or other areas. […] Breast cancer can recur in anyone who has had breast cancer. Its highly unlikely to be a result of anything you did or failed to do. […] There are, however, some things that seem to raise your risk of recurrence. These include: […] The higher the stage of your original tumor, the more likely it is to recur. […] If youre a woman and you get breast cancer before age 35, youre more likely than older women to get it again. […] Some types of breast cancer are more aggressive and therefore more likely to return and spread to other parts of your body. […] Recurrence is a risk for up to 32 years after a first diagnosis of breast cancer, according to a recent study. Your risk of recurrence after 10 years of remission depends on a number of things like: […] In general, once you have a breast cancer diagnosis, even if you are years in remission, its a good idea to be watchful and consult your doctor for regular breast exams and other screenings they think are appropriate. Early detection is the best way to get the best outcome from treatment.

• #88 Recurrent breast cancer – Hancock Health

  https://www.hancockhealth.org/mayo-health-library/recurrent-breast-cancer/

  Lack of endocrine therapy for hormone receptor-positive breast cancer. In people who have a certain type of breast cancer, not receiving endocrine therapy can raise their risk of recurrence. […] Cancer cells with certain characteristics. If you had triple negative breast cancer, you may have an increased risk of breast cancer recurrence. […] Obesity. Having a higher body mass index increases your risk of recurrence. […] Strategies that have been linked to a reduced risk of breast cancer recurrence include: Hormone therapy. Taking hormone therapy after your initial treatment may reduce the risk of recurrence if you have hormone receptor positive breast cancer. […] Chemotherapy. For people with breast cancer who have an increased risk of cancer recurrence, chemotherapy has been shown to decrease the chance that cancer will recur, and those who receive chemotherapy live longer.

• #89 Risks, Symptoms, and Treatments for Breast Cancer Recurrence – Ezra

  https://ezra.com/blog/breast-cancer-recurrence

  Breast cancer that comes back within five years of diagnosis and initial treatment is called early recurrence. Breast cancer that returns more than five years after diagnosis and initial treatment is called late recurrence. […] A bilateral mastectomy, or surgical removal of both breasts, significantly reduces your chances of breast cancer relapse. However, there is still a minimal chance that residual breast tissue or cancer cells could recur on the chest wall. […] Local breast cancer recurrence is when cancer comes back in the same area that the first tumor was found. […] Regional recurrence is when cancer reappears in the lymph nodes in the armpit or collarbone area near where the tumor was initially diagnosed. […] Distant breast cancer recurrence is when breast cancer has spread (metastasis) to another organ or part of your body, such as your lungs, bones, or brain. Though rare, distance recurrence can also occur in the opposite breast. […] You can assess your risk of cancer or cancer recurrence by taking ezras know-your-risk quiz, which evaluates questions about your lifestyle and medical history.

• #90 How Likely is Breast Cancer to Return after a Lumpectomy or Mastectomy?

  https://www.rockymountaincancercenters.com/blog/how-likely-is-breast-cancer-to-return-after-a-lumpectomy-or-mastectomy

  When breast cancer returns after initial treatment has ended, its called recurrent breast cancer. This is caused by a small number of undetectable cancer cells that were left behind. Over time these cells can develop into a new tumor in the breast. […] Although most recurring breast cancers happen within five years after diagnosis, recurrence can happen at any time. The risk of recurrence lessens over time but never decreases to zero. […] Recurrence is still possible for patients who had either type of surgery. There are studies that show lumpectomy patients have a slightly higher risk of breast cancer recurrence with a 15% chance for lumpectomy patients compared to 6% for mastectomy patients over the course of their lifetimes. […] Breast cancer does not always return. But its normal to be concerned about it. Here are some factors that make breast cancer more likely to return: Age at the time of first diagnosis having breast cancer before age 35 increases recurrence risk. The stage of your cancer when first diagnosed is determined by tumor size, grade, and if the cancer has spread. Recurrence is higher for patients with large tumors. Type of breast cancer aggressive cancers (inflammatory or triple-negative breast cancers) are more likely to recur and spread. Hormone receptor-positive breast cancer has a lower risk of recurrence if treatment includes hormone therapy. Lymph node-positive if breast cancer cells were found in the lymph nodes during your initial diagnosis the risk of recurrence increases. The type of treatment you had initially and when you had it. Studies show that giving a systemic treatment like chemotherapy after surgery and radiation can lower the risk of recurrence. Obesity increases your risk of recurrence. Trying to lower your weight and eat a healthy diet can help lower the likelihood of breast cancer returning.

• #91 Recurrent breast cancer – Hancock Health

  https://www.hancockhealth.org/mayo-health-library/recurrent-breast-cancer/

  For breast cancer survivors, factors that increase the risk of a recurrence include: Lymph node involvement. Finding cancer in nearby lymph nodes at the time of your original diagnosis increases your risk of the cancer coming back. Larger tumor size. People with larger tumors have a greater risk of recurrent breast cancer. Positive or close tumor margins. […] Lack of radiation treatment following a lumpectomy. Most people who choose a lumpectomy (wide local excision) for breast cancer undergo breast radiation therapy to reduce the risk of recurrence. […] Younger age. Younger people, particularly those under age 35 at the time of their original breast cancer diagnosis, face a higher risk of recurrent breast cancer. […] Inflammatory breast cancer. People with inflammatory breast cancer have a higher risk of local recurrence.

• #92 Recurrent breast cancer – Hancock Health

  https://www.hancockhealth.org/mayo-health-library/recurrent-breast-cancer/

  Radiation therapy. People whove had a breast-sparing operation to treat their breast cancer and those who had a large tumor or inflammatory breast cancer have a lower chance of the cancer recurring if theyre treated with radiation therapy. […] If your doctor suspects you may have recurrent breast cancer based on results of a mammogram or physical exam, or because of signs and symptoms, he or she may recommend additional tests to confirm the diagnosis. […] Your treatment options will depend on several factors, including the extent of the disease, its hormone receptor status, the type of treatment you received for your first breast cancer and your overall health. […] Treatment for a local recurrence typically starts with an operation and may include radiation if you havent had it before. Chemotherapy and hormone therapy also may be recommended.

• #93 Recurrent breast cancer – Hancock Health

  https://www.hancockhealth.org/mayo-health-library/recurrent-breast-cancer/

  Lack of endocrine therapy for hormone receptor-positive breast cancer. In people who have a certain type of breast cancer, not receiving endocrine therapy can raise their risk of recurrence. […] Cancer cells with certain characteristics. If you had triple negative breast cancer, you may have an increased risk of breast cancer recurrence. […] Obesity. Having a higher body mass index increases your risk of recurrence. […] Strategies that have been linked to a reduced risk of breast cancer recurrence include: Hormone therapy. Taking hormone therapy after your initial treatment may reduce the risk of recurrence if you have hormone receptor positive breast cancer. […] Chemotherapy. For people with breast cancer who have an increased risk of cancer recurrence, chemotherapy has been shown to decrease the chance that cancer will recur, and those who receive chemotherapy live longer.

• #94 How Likely is Breast Cancer to Return after a Lumpectomy or Mastectomy?

  https://www.rockymountaincancercenters.com/blog/how-likely-is-breast-cancer-to-return-after-a-lumpectomy-or-mastectomy

  When breast cancer returns after initial treatment has ended, its called recurrent breast cancer. This is caused by a small number of undetectable cancer cells that were left behind. Over time these cells can develop into a new tumor in the breast. […] Although most recurring breast cancers happen within five years after diagnosis, recurrence can happen at any time. The risk of recurrence lessens over time but never decreases to zero. […] Recurrence is still possible for patients who had either type of surgery. There are studies that show lumpectomy patients have a slightly higher risk of breast cancer recurrence with a 15% chance for lumpectomy patients compared to 6% for mastectomy patients over the course of their lifetimes. […] Breast cancer does not always return. But its normal to be concerned about it. Here are some factors that make breast cancer more likely to return: Age at the time of first diagnosis having breast cancer before age 35 increases recurrence risk. The stage of your cancer when first diagnosed is determined by tumor size, grade, and if the cancer has spread. Recurrence is higher for patients with large tumors. Type of breast cancer aggressive cancers (inflammatory or triple-negative breast cancers) are more likely to recur and spread. Hormone receptor-positive breast cancer has a lower risk of recurrence if treatment includes hormone therapy. Lymph node-positive if breast cancer cells were found in the lymph nodes during your initial diagnosis the risk of recurrence increases. The type of treatment you had initially and when you had it. Studies show that giving a systemic treatment like chemotherapy after surgery and radiation can lower the risk of recurrence. Obesity increases your risk of recurrence. Trying to lower your weight and eat a healthy diet can help lower the likelihood of breast cancer returning.

• #95 What’s the Risk of Breast Cancer Recurrence After Mastectomy? 11 Symptoms To Watch For | MyBCTeam

  https://www.mybcteam.com/resources/whats-the-risk-of-breast-cancer-recurrence-after-mastectomy-symptoms-to-watch-for

  After completing breast cancer treatment, you and your loved ones might worry about the possibility of the cancer returning, known as recurrence. Breast cancer can recur (return) if treatment doesn’t eliminate all cancer cells. Even after a double mastectomy a surgery that removes all breast tissue from both breasts there is still a possibility of recurrence. […] About 5 in every 100 women who undergo a mastectomy for breast cancer will experience a local recurrence within 10 years of their initial diagnosis. […] About 5 in every 100 women who undergo a mastectomy for breast cancer experience a local recurrence meaning the cancer returns in the chest area within 10 years of their initial diagnosis. […] The chance of recurrence is further influenced by whether the cancer was found in nearby lymph nodes and the type of follow-up treatments received. If no cancer is detected in the lymph nodes, the risk of recurrence is about 6 percent within five years after a mastectomy. If cancer is found in nearby lymph nodes, the risk or recurrence increases to around 25 percent.

• #96 Breast Cancer Recurrence: Rates, Signs & Treatment

  https://my.clevelandclinic.org/health/diseases/8328-breast-cancer-recurrence

  Distant (metastatic or Stage 4) breast cancer can involve any organ, including your bones, lungs, brain or liver. Symptoms depend on where the cancer spreads. You may experience: Pain where breast cancer has spread, including bone pain. Chronic dry cough. Dizziness, balance problems or seizures. Extreme fatigue. Loss of appetite, nausea and weight loss. Severe headaches. Numbness or weakness. […] Breast cancer recurrence happens when treatment doesn’t kill all the cancer cells in your breast. Breast cancer treatments are effective, but breast cancer cells can be tricky: Treatment can shrink breast cancer tumors to the point that tests don’t detect weakened cancer cells. But the cells are still there, and over time, they can return stronger, start to grow and create tumors. […] Recurrent breast cancer can be more challenging to treat, but that doesn’t mean it’s always worse than the original breast cancer. If you have recurrent breast cancer, you may have different treatment than before, or more aggressive treatment such as surgery or more powerful anticancer drugs. […] In general, your chances of being alive five years after diagnosis are: 99% for localized breast cancer. 86% for regional breast cancer. 27% for distant (metastatic) breast cancer.

• #97 How Likely is Breast Cancer to Return after a Lumpectomy or Mastectomy?

  https://www.rockymountaincancercenters.com/blog/how-likely-is-breast-cancer-to-return-after-a-lumpectomy-or-mastectomy

  Treating recurrent breast cancer usually includes different treatments than the first time. This is because previous treatments may no longer be effective, or tumors develop tolerance to chemotherapy drugs. Metastatic cancer in distant areas of the body will be treated as breast cancer with breast cancer drugs. […] Follow-up care is especially important after breast surgery because your risk of recurrent breast cancer never goes away completely. […] If you develop symptoms or your oncologist thinks cancer may have recurred, you may have blood tests, biopsy, or imaging testing (X-rays, CT, or PET scans). You should also watch for any new symptoms such as a new lump or other changes in your breast. […] Survival statistics for five years after a recurrent breast cancer diagnosis are: Localized recurrent breast cancer – 99% Regional recurrence – 86% Distant or metastatic – 27%. […] Yes! There are a number of lifestyle choices you can make that, along with medical treatments, can potentially eliminate or reduce your breast cancer recurrence risk.

• #98 Breast cancer recurrence | Macmillan Cancer Support

  https://www.macmillan.org.uk/cancer-information-and-support/breast-cancer/breast-cancer-recurrence

  Breast cancer that comes back is called a recurrence. There are different types of recurrence. […] Symptoms of breast cancer recurrence […] After breast cancer treatment you may worry that any symptom you have is caused by the cancer. It can be hard to know what to look out for. […] It is important to let your cancer doctor or nurse know about any symptoms or side effects that do not improve. If you notice anything unusual between appointments, contact your cancer doctor or breast care nurse straight away. […] Breast cancer that comes back in another part of the body is called secondary breast cancer. We also have information about possible symptoms of secondary breast cancer. […] Sometimes breast cancer comes back in the treated breast or the scar. This is called a local recurrence.

• #99 Breast Cancer: Symptoms, Risk Factors & Treatments | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/breast-cancer.html

  Breast cancer symptoms vary from person to person and there is no exact definition of what a lump or mass feels like. […] Breast cancer symptoms may include: Lump or mass in the breast, Lump or mass in the armpit, Breast skin changes, including skin redness and thickening of the breast skin, resulting in an orange-peel texture, Dimpling or puckering on the breast, Discharge from the nipple, Scaliness on nipple, which sometimes extends to the areola, Nipple changes, including the nipple turning inward, pulling to one side or changing direction, An ulcer on the breast or nipple, sometimes extending to the areola, Swelling of the breast. […] These symptoms do not always mean you have breast cancer. However, it is important to discuss any symptoms with your doctor, since they may also signal other health problems.

• #100 Breast cancer recurrence symptoms and signs | LBBC

  https://www.lbbc.org/about-breast-cancer/symptoms/signs-recurrence

  During and after breast cancer treatment, you will have regular check-ups with your doctor to look for any signs of cancer returning. […] Common signs of a local recurrence are changes in the breast, such as skin inflammation or a lump. […] Signs of recurrence may include: A lump or growth in the breast area, A change in the size or shape of your breast, Skin irritation, redness, swelling or itching, Discharge from your nipple that is not breast milk. […] Breast cancer can come back in organs other than the breast, in distant parts of the body. […] When breast cancer spreads to a distant part of the body, it is called a metastatic or distant recurrence. […] Often, signs of metastatic recurrence appear at the site where the cancer has spread. […] If you have this type of pain and it does not go away, you should seek medical attention.

• #101 Breast Cancer, Metastatic or Recurrent | CommonSpirit Health

  https://www.commonspirit.org/conditions-treatments/breast-cancer-metastatic-or-recurrent

  Breast cancer is the uncontrolled growth of abnormal cells in one or both breasts. Metastatic breast cancer means that cancer has spread to other parts of the body. Recurrent breast cancer means that cancer has come back in or near the original site or in another part of the body. This may happen from a few months to many years after the first diagnosis. […] The symptoms of metastatic or recurrent breast cancer depend on how much and where the cancer has spread. Not all people have symptoms. […] Symptoms of metastatic breast cancer may include: Bone pain. Shortness of breath. Pain in the belly or yellow, itchy skin. Confusion, headaches, or seizures. […] If cancer comes back in the same breast or in your mastectomy scar, you may have symptoms such as: A lump or thickening in the breast, chest wall, or armpit. A change in the skin on your chest or the size or shape of the breast. Discharge or bleeding from the nipple that occurs without squeezing the nipple. A change in the nipple, such as a scaly or crusty look or a nipple that pulls inward. […] If cancer comes back in another part of your body, such as your lungs, you may have the same symptoms as metastatic breast cancer.

• #102 Breast cancer recurrence symptoms | Breast Cancer Now

  https://breastcancernow.org/about-breast-cancer/diagnosis/breast-cancer-recurrence/breast-cancer-recurrence-symptoms

  The risk of breast cancer recurring is higher in the first few years and usually reduces as time goes on. […] However, recurrence can happen even many years after treatment. […] Its important to continue to be breast and body aware and report any changes to your treatment team or GP. […] Whether youve had breast-conserving surgery or a mastectomy with or without reconstruction, its important to be aware of any changes to the breast, chest or surrounding area, even if youre having follow-up appointments or regular mammograms. […] If you have pain that gets worse or is severe, contact your treatment team or GP. […] Its also important to be aware of any new changes in the other breast and to report these as soon as possible.

• #103 Signs and symptoms to look out for | The Royal Marsden

  https://www.royalmarsden.nhs.uk/oafu/signs-and-symptoms-look-out

  What to be aware of and how to check yourself for symptoms of a recurrence. […] However, sometimes breast cancer can return: […] In the treated breast (this is called local recurrence) […] […] In the lymph nodes in the armpit or around the collar bone (this is called regional recurrence) […] […] Elsewhere in the body (this is called distant recurrence or metastatic/secondary breast cancer) […] It can be frightening if you are diagnosed with a recurrence or a new breast cancer in the other breast. However, it is important to remember that it can usually be fully treated. […] Symptoms in the breast and armpit area: […] New lump or swelling of the breast, or skin over the chest wall if you have had a mastectomy […] […] Dimpling, puckering or a raised spot on your breast/mastectomy skin area […]

• #104 Signs and symptoms to look out for | The Royal Marsden

  https://www.royalmarsden.nhs.uk/oafu/signs-and-symptoms-look-out

  New nipple discharge or retraction (drawing in) of the nipple […] Symptoms in the rest of the body: […] New ongoing pain in the body such as hips or back which does not get better with painkillers, and is often worse at night, or wakes you at night […] […] New pins and needles or reduced sensation in your arms or legs […] […] Unexplained weight loss or loss of appetite […] […] Constant nausea/feeling sick […] […] Dry cough or shortness of breath which does not appear to be related to a cold/chest infection […] […] Severe headache, usually worse in the morning […] […] Pain in the upper abdomen which does not settle down

• #105 Warning Signs of Cancer Recurrence | UPMC HealthBeat

  https://share.upmc.com/2017/11/warning-signs-cancer-recurrence-survivors/

  The symptoms of a local cancer recurrence are specific to the original cancer. With breast cancer, these warning signs can include: A new lump in the breast. Changes to the surrounding skin. […] If the recurrence is regional, the symptoms might involve a lump where nearby lymph nodes are located, such as in the: Collarbone, Neck, Underarm. […] Warning signs of a distant recurrence tend to involve a different body part from the original cancer site. For example, if cancer recurs in the lungs, you might experience coughing and difficulty breathing. A recurrence of cancer in the brain can cause seizures and headaches. Bone pain also can be a symptom of cancer recurrence. […] If you experience worrisome symptoms or notice changes to your health, talk to your doctor as soon as possible.

• #106 Breast cancer: Learn More – Recurrent non-metastatic breast cancer – InformedHealth.org – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK279424/

  If breast cancer comes back, it is often more frightening than the first time it was diagnosed. But even if it does come back, there are still treatment options. It is often possible to remove the new tumor and prevent the cancer from spreading further. Daily help and support can be important in maintaining a good quality of life. […] If breast cancer comes back after going away, it is known as recurrent breast cancer. That usually means that some cancer cells remained inside the body despite treatment, and that they have started to grow again. This can happen years or even decades after the first illness. […] Signs of breast cancer recurrence may include a lump in the breast, scar tissue or the chest area, as well as inflamed skin. […] If it is possible to completely remove the tumor and there are no distant metastases, even recurrent breast cancer can be cured.

• #107 Recurrent breast cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/recurrent-breast-cancer/diagnosis-treatment/drc-20377141

  If your doctor suspects you may have recurrent breast cancer based on results of a mammogram or physical exam, or because of signs and symptoms, he or she may recommend additional tests to confirm the diagnosis. […] A pathologist can determine if the cancer is a recurrence of cancer or a new type of cancer. […] Treatment for a local recurrence typically starts with an operation and may include radiation if you haven’t had it before. […] Many treatments exist for metastatic breast cancer. Your options will depend on where your cancer has spread. […] In general, the goal of treatment for metastatic breast cancer isn’t to cure the disease. Treatment may allow you to live longer and can help relieve symptoms the cancer is causing. […] If you have any signs or symptoms that worry you, make an appointment with your primary care doctor or family doctor. […] Your doctor can recommend the necessary tests and procedures to confirm a diagnosis of recurrent cancer.

• #108 The lingering mysteries of metastatic recurrence in breast cancer | British Journal of Cancer

  https://www.nature.com/articles/s41416-020-01161-4

  The development over the past decade of non-invasive biomarker assays promises to enable the low-cost early detection of cancer. […] Several of these assays have demonstrated success in the early detection of breast cancer recurrence. […] This window of lead time in which ctDNA is detectable in blood, but metastatic recurrence is not yet visible on imaging, provides an exciting opportunity to treat the disease during the dormancy phase. […] Despite the urgency, however, an understanding of the biological underpinnings of relapse is still lacking.

• #109 Breast Cancer Recurrence: Types, Symptoms and Risk

  https://www.cancercenter.com/cancer-types/breast-cancer/types/rare-breast-cancer-types/recurrent-breast-cancer

  Pay special attention to these symptoms, which could signal a breast cancer recurrence: Weight loss without trying, Headaches, bone pain or any new or different pain that the patient cant explain, Shortness of breath or wheezing, Seizures, Fatigue, Fever, chills or a cough that wont get better, Yellow tinge to skin and eyes (jaundice), Easy bruising or bleeding, Digestive issues, like nausea, vomiting, diarrhea, loss of appetite or trouble swallowing, Blood in the urine or stools, Any new lumps or areas of swelling. […] In general, the more time that goes by, the lower the risk of recurrence. Cancer is most likely to recur in the first two years after treatment, and once people get to five years of living cancer-free after treatment, its considered to be a significant milestone to be celebrated. Recurrence after that five year markrare, but possibleis called late recurrence. […] If the care team suspects a cancer recurrence, theyll recommend diagnostic tests, like lab tests, imaging or biopsies, both to be sure the cancer has come back and to get more information to guide treatment.

• #110 Risks, Symptoms, and Treatments for Breast Cancer Recurrence – Ezra

  https://ezra.com/blog/breast-cancer-recurrence

  Breast cancer has the highest risk of returning during the first two years after your original cancer is treated. While your risk of recurrence is never zero, it goes down over time. […] Finding out that you have recurrent breast cancer can almost feel more terrifying than an initial diagnosis. If you do receive such news, dont panic. While it may feel alarming and disheartening, the right treatment can eliminate breast cancer just as it did the first time. […] Youll likely recognize the symptoms if you have a breast cancer relapse. They will be much the same as what you experienced with your original breast cancer diagnosis, with a few additional possible signs at the treatment areas: A new lump in the breast, A new part of the breast that feels too firm, Redness or swelling of the skin on your breast, Abnormal changes to the nipple, Pulling of the skin or swelling at the lumpectomy site, Increased thickening on or near the mastectomy scar.

• #111 Breast Cancer Recurrence: What to Expect and How It’s Treated | BASS Medical Group

  https://www.bassmedicalgroup.com/blog-post/breast-cancer-recurrence-what-to-expect-if-breast-cancer-comes-back

  If your doctor suspects a recurrence, additional imaging and biopsy tests will confirm the diagnosis. Your treatment plan will depend on the location of recurrence, your previous treatments, and receptor status (such as HER2-positive or hormone-receptor positive cancer). […] A recurrence diagnosis can feel like starting over but it’s not the end of the road. Many women with recurrent breast cancer go on to live full, meaningful lives with proper treatment and support.

• #112 Breast cancer: Learn More – Recurrent non-metastatic breast cancer – InformedHealth.org – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK279424/

  Removing lymph nodes from the area around the affected breast and the armpit can cause lymphedema. This is where the arm or chest on the affected side becomes swollen because lymph fluid (lymph) builds up there. It is important to treat lymphedema as soon as possible because symptoms can get worse over time and then become more difficult to treat. […] Many women say that it comes as a relief to accept feelings of anxiety, worries and despair and to talk about them with people close to them.

• #113 Recurrent Breast Cancer: Causes, Symptoms, and Treatments | SELF

  https://www.self.com/story/recurrent-breast-cancer

  If your first cancer was treated with lumpectomy, your doctor may recommend a mastectomy to remove all of your breast tissue. […] If your first breast cancer was treated with mastectomy and the cancer comes back in the chest wall, you may have surgery to remove the new cancer along with a margin of normal tissue. […] A local recurrence may be accompanied by hidden cancer in nearby lymph nodes. For this reason, the surgeon may remove some or all of the nearby lymph nodes if they weren’t removed during your initial treatment. […] If it’s possible, surgery to remove the cancer is the recommended treatment for a regional recurrence. […] Sometimes radiation therapy may be used after surgery. If surgery isn’t possible, radiation therapy may be used as the main treatment for a regional breast cancer recurrence.

• #114 Survival and Risk of Recurrence – Susan G. Komen®

  https://www.komen.org/breast-cancer/treatment/recurrence/survival-and-risk-of-recurrence/

  Everyone whos had breast cancer is at risk of recurrence (return of breast cancer). However, most people diagnosed with breast cancer will never have a recurrence. […] If you have a breast cancer recurrence, its not your fault. You did nothing to cause it. […] Local recurrence is the return of cancer to the breast, chest wall or nearby lymph nodes after treatment. Most local recurrences occurs within the first 5 years after diagnosis. If you have a local recurrence, youll need more treatment. […] Distant recurrence occurs when cancer spreads beyond the breast and nearby lymph nodes to other organs such as the bones, liver, lungs or brain. This is also called metastatic, stage IV or advanced breast cancer. […] For women with early breast cancer who have a lumpectomy plus radiation therapy, the risk of local recurrence depends on tumor characteristics, including biomarkers (such as hormone receptor status and HER2 status).

• #115 When Breast Cancer Comes Back

  https://www.webmd.com/breast-cancer/breast-cancer-comes-back

  Its when your cancer comes back after treatment. It can happen a year after you finish treatment for breast cancer, or 5, 10, even 20 years later. You find another lump, or a shadow appears on your mammogram. Is the cancer back? […] In simple terms, it means the return of the same cancer. […] It could also mean the cancer has spread to other parts of the body. Doctors call this metastatic recurrence. This is generally more serious than a simple return of cancer cells to the breast itself, which is also a recurrence. […] The more your cancer spreads from the original tumor, the more serious it is likely to be. Your cancer may be local, regional, or distant: […] Local: The cancer comes back in the same breast as the original tumor. […] Regional: Here, the cancer returns to the same area as the original tumor, but in a more expanded sense that includes the armpit or collarbone lymph nodes.

• #116 Stage 4 (IV) Breast Cancer: Survival Rates, Treatment & Prognosis

  https://www.nationalbreastcancer.org/breast-cancer-stage-4/

  There is no cure for Stage 4 breast cancer, but it is possible for Stage 4 breast cancer to go into remission. This is also called “no evidence of disease,” or NED. When Stage 4 breast cancer is NED, it means that the cancer is not visible on imaging or other tests, but is likely still in the body at a level that is too small to detect. […] Stage 4 breast cancer is the most advanced and most life-threatening stage of breast cancer. There is no known cure for Stage 4 breast cancer, with the focus of treatment being quality of life for the patient. […] It is not uncommon for all stages of breast cancer, including Stage 4, to produce no noticeable symptoms when the cancer first develops. However, as Stage 4 breast cancer progresses and spreads, symptoms will begin to appear. It is important to report any and all symptoms of Stage 4 breast cancer to your doctor or oncologist as soon as you are aware of them.

• #117 Recurrent breast cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/recurrent-breast-cancer/diagnosis-treatment/drc-20377141

  If your doctor suspects you may have recurrent breast cancer based on results of a mammogram or physical exam, or because of signs and symptoms, he or she may recommend additional tests to confirm the diagnosis. […] A pathologist can determine if the cancer is a recurrence of cancer or a new type of cancer. […] Treatment for a local recurrence typically starts with an operation and may include radiation if you haven’t had it before. […] Many treatments exist for metastatic breast cancer. Your options will depend on where your cancer has spread. […] In general, the goal of treatment for metastatic breast cancer isn’t to cure the disease. Treatment may allow you to live longer and can help relieve symptoms the cancer is causing. […] If you have any signs or symptoms that worry you, make an appointment with your primary care doctor or family doctor. […] Your doctor can recommend the necessary tests and procedures to confirm a diagnosis of recurrent cancer.

• #118

  https://content.irisoncology.com/library/recurrent-breast-cancer

  Recurrent breast cancer is breast cancer that comes back after initial treatment. Although the initial treatment is aimed at eliminating all cancer cells, a few may have evaded treatment and survived. These undetected cancer cells multiply, becoming recurrent breast cancer. […] Recurrent breast cancer may occur months or years after your initial treatment. The cancer may come back in the same place as the original cancer (local recurrence), or it may spread to other areas of your body (distant recurrence). […] Signs and symptoms of recurrent breast cancer vary depending on where the cancer comes back. […] In a local recurrence, cancer reappears in the same area as your original cancer. […] Signs and symptoms of local recurrence within the same breast may include: A new lump in your breast or irregular area of firmness. Changes to the skin of your breast. Skin inflammation or area of redness. Nipple discharge.

• #119

  https://content.irisoncology.com/library/recurrent-breast-cancer

  Signs and symptoms of local recurrence on the chest wall after a mastectomy may include: One or more painless nodules on or under the skin of your chest wall. A new area of thickening along or near the mastectomy scar. […] A regional breast cancer recurrence means the cancer has come back in the nearby lymph nodes. […] Signs and symptoms of regional recurrence may include a lump or swelling in the lymph nodes located: Under your arm. Near your collarbone. In the groove above your collarbone. In your neck. […] A distant (metastatic) recurrence means the cancer has traveled to distant parts of the body, most commonly the bones, liver and lungs. […] Signs and symptoms include: Persistent and worsening pain, such as chest, back or hip pain. Persistent cough. Difficulty breathing. Loss of appetite. Weight loss without trying. Severe headaches. Seizures.

• #120 Signs of Breast Cancer Recurrence

  https://www.healthline.com/health/breast-cancer/signs-of-recurrence

  In general, triple-negative breast cancers and HER2-amplified breast cancers are most likely to recur compared to luminal A breast cancers (estrogen receptor-positive, progesterone receptor-positive, and HER2-negative breast cancers), which are least likely to return. […] More advanced breast cancers that have nodal involvement are more likely to recur than early stage breast cancers. […] The chances of a recurrence are also dependent upon age. An older woman with an early stage hormone-receptor breast cancer who undergoes breast conservation plus radiation and anti-estrogen therapy will have a recurrence rate of about 2% in 10 years. This is very different than a young woman with advanced triple-negative breast cancer their chance of recurrence is significantly higher. […] Typically, triple-negative and HER2-positive breast cancers are much more likely to return within 5 years of diagnosis, if they are going to return at all.

• #121 Signs of Breast Cancer Recurrence

  https://www.healthline.com/health/breast-cancer/signs-of-recurrence

  If a woman has a luminal A tumor, then it can recur many years later. For example, we sometimes see a recurrence of estrogen-sensitive breast cancers 10-plus years after initial diagnosis. […] A locally advanced tumor is more likely to recur sooner than a less aggressive, smaller tumor. […] Young women with more aggressive tumors and more advanced stages (triple-negative breast cancer or HER2-positive breast cancers) have a much higher chance of recurrence. […] However, in elderly women with very early stages of breast cancer, a very small percentage have a breast cancer recurrence often less than 2% in 10 years. […] A woman who treated her initial breast cancer with a lumpectomy may feel a palpable mass or lump, have nipple changes or bloody nipple discharge, or experience skin changes. This can be a sign that the breast cancer has returned.

• #122 Stage 4 (IV) Breast Cancer: Survival Rates, Treatment & Prognosis

  https://www.nationalbreastcancer.org/breast-cancer-stage-4/

  There is no cure for Stage 4 breast cancer, but it is possible for Stage 4 breast cancer to go into remission. This is also called “no evidence of disease,” or NED. When Stage 4 breast cancer is NED, it means that the cancer is not visible on imaging or other tests, but is likely still in the body at a level that is too small to detect. […] Stage 4 breast cancer is the most advanced and most life-threatening stage of breast cancer. There is no known cure for Stage 4 breast cancer, with the focus of treatment being quality of life for the patient. […] It is not uncommon for all stages of breast cancer, including Stage 4, to produce no noticeable symptoms when the cancer first develops. However, as Stage 4 breast cancer progresses and spreads, symptoms will begin to appear. It is important to report any and all symptoms of Stage 4 breast cancer to your doctor or oncologist as soon as you are aware of them.

• #123 Cancer Recurrence – Why Does Cancer Come Back | City of Hope

  https://www.cancercenter.com/cancer-recurrence

  While cancer doesn’t always return, recurrence is common for some hard-to-treat forms of cancer. These recurrences usually follow certain patterns of local, regional or distant disease. Patients should be aware of these potential developments to look for signs of recurrence so it may be diagnosed as early as possible. […] Cancer may be more likely to return if it had already spread when it was first detected. […] With recurrent breast cancer, most local recurrences happen within five years after treatment of an initial tumor, according to the Susan G. Komen Foundation. The risk for distant or metastasized recurrence remains the same whether you had a lumpectomy and radiation therapy or a mastectomy. […] If the cancer has returned and spread to distant sites, it’s called metastatic cancer. Common sites for distant tumors are the bones, liver and lungs, but cancer may spread to any tissue. Metastatic cancer symptoms depend on the size and location of tumors and not all metastatic cancer results in symptoms. […] If you’re diagnosed with recurrent cancer that has spread to distant sites, treatment usually focuses on trying to control its growth. Efforts to maintain quality of life and reduce discomfort, called palliative care, may also be made.

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