Materiały źródłowe

• #1 The Epidemiological and Clinical Aspects of Nasal Polyps that Require Surgery

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3846212/

  The objective of this retrospective cross-sectional study was to obtain epidemiological data from the charts of 297 patients with nasal polyposis who were operated on in a referral hospital in Mashhad and to determine the frequency of the presenting symptoms of nasal polyps. […] This study highlights the need for large-scale epidemiologic research exploring the prevalence and incidence of nasal polyposis in Iran. […] Nasal polyps are mucosal lesions of the nasal or paranasal sinuses that can result from a response to inflammatory or infectious stimuli. They appear as smooth, round, semi-translucent masses that are most commonly found in the middle meatus and ethmoid sinuses and affect 1% to 4% of the population. […] The prevalence of nasal polyposis is higher in subjects with asthma than in non-asthmatics and 16.5% of asthmatic patients over 40 years of age have been shown to have nasal polyps. […] An overview of the currently available literature illustrates the paucity of accurate information on the epidemiology of nasal polyposis especially in Iran, and highlights the need for large-scale epidemiologic research exploring the prevalence and incidence of nasal polyposis.

• #2 The prevalence and burden of nasal polyps

  https://www.aaaai.org/tools-for-the-public/latest-research-summaries/the-journal-of-allergy-and-clinical-immunology-in/2021/burden

  Chronic rhinosinusitis with nasal polyps (CRSwNP) is a major health problem which causes a significant burden on quality of life and has a huge economic impact. Current estimates of prevalence of nasal polyposis in western settings have mostly relied on patient questionnaires and do not include the gold standard of nasal endoscopy for diagnosis. […] In a retrospective population-based study published in The Journal of Allergy and Clinical Immunology: In Practice by Campion et al., the prevalence of nasal polyps in an Austrian community-based population where more than 10,000 patients underwent endoscopic examination of their nose was investigated. […] The adjusted prevalence of nasal polyps in this central European population was found to be 1.95%. […] Interestingly, 24.8% of patients were found to have clinically silent polyps in that they did not meet the current diagnostic criteria for CRSwNP and had no wish for treatment.

• #3 The prevalence and burden of nasal polyps

  https://www.aaaai.org/tools-for-the-public/latest-research-summaries/the-journal-of-allergy-and-clinical-immunology-in/2021/burden

  Chronic rhinosinusitis with nasal polyps (CRSwNP) is a major health problem which causes a significant burden on quality of life and has a huge economic impact. Current estimates of prevalence of nasal polyposis in western settings have mostly relied on patient questionnaires and do not include the gold standard of nasal endoscopy for diagnosis. […] In a retrospective population-based study published in The Journal of Allergy and Clinical Immunology: In Practice by Campion et al., the prevalence of nasal polyps in an Austrian community-based population where more than 10,000 patients underwent endoscopic examination of their nose was investigated. […] The adjusted prevalence of nasal polyps in this central European population was found to be 1.95%. […] Interestingly, 24.8% of patients were found to have clinically silent polyps in that they did not meet the current diagnostic criteria for CRSwNP and had no wish for treatment.

• #4 Epidemiology of Nasal Polyposis | SpringerLink

  https://link.springer.com/chapter/10.1007/978-3-030-21217-9_42

  Nasal polyps (NP) are benign, edematous masses growing into nasal cavity that could have multiple etiological factors. […] The prevalence of NP in the general population is unclear. It varies from 0.2% to 5.6%. […] The prevalence of NP shows a wide range according to etiology. […] The most important data on the epidemiology of NP are obtained from NP etiology studies. […] There may be hereditary factors for NP but there is limited knowledge in this area. […] However, we have some evidence for genetic inheritance. Studies reported that up to 14% of patients with NP have a family history. […] A link has been indicated that NP and asthma have an association with HLA-A1B8 and HLA-A74 genes. […] The main hypotheses that lead to the development of NP will be discussed below with the current incidence and prevalence rates.

• #5 The Epidemiological and Clinical Aspects of Nasal Polyps that Require Surgery

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3846212/

  The objective of this retrospective cross-sectional study was to obtain epidemiological data from the charts of 297 patients with nasal polyposis who were operated on in a referral hospital in Mashhad and to determine the frequency of the presenting symptoms of nasal polyps. […] This study highlights the need for large-scale epidemiologic research exploring the prevalence and incidence of nasal polyposis in Iran. […] Nasal polyps are mucosal lesions of the nasal or paranasal sinuses that can result from a response to inflammatory or infectious stimuli. They appear as smooth, round, semi-translucent masses that are most commonly found in the middle meatus and ethmoid sinuses and affect 1% to 4% of the population. […] The prevalence of nasal polyposis is higher in subjects with asthma than in non-asthmatics and 16.5% of asthmatic patients over 40 years of age have been shown to have nasal polyps. […] An overview of the currently available literature illustrates the paucity of accurate information on the epidemiology of nasal polyposis especially in Iran, and highlights the need for large-scale epidemiologic research exploring the prevalence and incidence of nasal polyposis.

• #6 Clinical Aspects of Patients with Nasal Polyposis

  http://www.arquivosdeorl.org.br/conteudo/acervo_eng.asp?Id=625

  The nasal polyposis has a great impact on the patients’ life quality, and brings social and occupational limitations. It is estimate that the incidence in the general population is of about 1 to 4% […] The main complaints of the patients are usually nasal obstruction, rhinorrhea, posterior discharge, headache, hyposmia/anosmia and coughing. […] The nasal polyposis is a common disease in the population, with prevalence of about 4%. […] The severity of the tomographic findings is higher in patients who presented AAS intolerance and asthma.

• #7 The prevalence and burden of nasal polyps

  https://www.aaaai.org/tools-for-the-public/latest-research-summaries/the-journal-of-allergy-and-clinical-immunology-in/2021/burden

  Chronic rhinosinusitis with nasal polyps (CRSwNP) is a major health problem which causes a significant burden on quality of life and has a huge economic impact. Current estimates of prevalence of nasal polyposis in western settings have mostly relied on patient questionnaires and do not include the gold standard of nasal endoscopy for diagnosis. […] In a retrospective population-based study published in The Journal of Allergy and Clinical Immunology: In Practice by Campion et al., the prevalence of nasal polyps in an Austrian community-based population where more than 10,000 patients underwent endoscopic examination of their nose was investigated. […] The adjusted prevalence of nasal polyps in this central European population was found to be 1.95%. […] Interestingly, 24.8% of patients were found to have clinically silent polyps in that they did not meet the current diagnostic criteria for CRSwNP and had no wish for treatment.

• #8 Nasal polyps. A clinical study of endoscopic score systems and epidemiology

  https://gupea.ub.gu.se/handle/2077/15994

  Nasal polyps are a common disease, the etiology and pathogenesis of which are still unclear. […] The epidemiology of nasal polyps in the general population is not known. […] The prevalence of nasal polyps in adults was 2.7%, and was more frequent among men and asthmatics, as well as with increasing age. […] The prevalence of nasal polyps was 2.7% in the general adult population studied.

• #9 Recorded prevalence of nasal polyps increases with age

  https://www.termedia.pl/Recorded-prevalence-of-nasal-polyps-increases-with-age,7,41897,1,1.html

  Recorded prevalence of nasal polyps increases with age. Patients with nasal polyps account for approximately 10-30% of all CRS patients. This condition typically affects middle-aged and elderly patients, average age at diagnosis is 40 to 60 years, and it is more frequent in men. The overall prevalence of nasal polyps in adults according to published epidemiological studies ranges from 1% to 4%. The recorded prevalence of CRSwNP in Poland was 52.0 per 10,000 population (64.6/10,000 for men, 40.2/10,000 for women) and varied: a) between administrative regions: from 43.1/10,000 to 62.7/10,000; b) 60.0/10,000 in cities (75.3/10,000 among men and 46.3/10,000 among women) and 39.9/10,000 in rural areas (49.1/10,000 among men and 30.7/10,000 among women). CRSwNP was much more frequent in patients aged 55-59 (98.1/10,000) and 75-79 years (98.7/10,000). Among men, the highest prevalence was in the 75-79 age group (164.3/10,000). Among women, prevalence peaked in the 55-59 age group (75.1/10,000). Nasal polyps are more than one and a half times as prevalent in men than in women. The recorded prevalence of nasal polyps increases with age and the rates peak in men aged 75-79 years and in women aged 55-59 years. Higher prevalence of CRSwNP is recorded in urban areas compared to rural areas. The NHF data in comparison with a population-wide epidemiological study shows that a large proportion of patients with nasal polyps do not receive regular treatment or even do not seek medical attention.

• #10 The prevalence and burden of nasal polyps

  https://www.aaaai.org/tools-for-the-public/latest-research-summaries/the-journal-of-allergy-and-clinical-immunology-in/2021/burden

  Chronic rhinosinusitis with nasal polyps (CRSwNP) is a major health problem which causes a significant burden on quality of life and has a huge economic impact. Current estimates of prevalence of nasal polyposis in western settings have mostly relied on patient questionnaires and do not include the gold standard of nasal endoscopy for diagnosis. […] In a retrospective population-based study published in The Journal of Allergy and Clinical Immunology: In Practice by Campion et al., the prevalence of nasal polyps in an Austrian community-based population where more than 10,000 patients underwent endoscopic examination of their nose was investigated. […] The adjusted prevalence of nasal polyps in this central European population was found to be 1.95%. […] Interestingly, 24.8% of patients were found to have clinically silent polyps in that they did not meet the current diagnostic criteria for CRSwNP and had no wish for treatment.

• #11 The prevalence and burden of nasal polyps

  https://www.aaaai.org/tools-for-the-public/latest-research-summaries/the-journal-of-allergy-and-clinical-immunology-in/2021/burden

  After adapting the currently available guidelines on the use of biologics in nasal polyps it was found that between 6 and 13% of patients with nasal polyps would be eligible for biological therapy. […] This study is the first to highlight that in a community-based population a significant proportion of nasal polyps are asymptomatic and do not require treatment. It is also the first to estimate the number of patients who would, according to current guidelines, be eligible for newly available biological therapies.

• #12 Nasal Polyps: Causes, Symptoms, and Treatment Doctor

  https://patient.info/doctor/nasal-polyps-pro

  The population prevalence is reported as around 4%, with no racial predilection. The male-to-female ratio is approximately 2:1. […] The evidence relating to the effectiveness of different types of surgery versus medical treatment for adults with chronic rhinosinusitis with nasal polyps is of low quality and further research is needed, including into new therapies such as biologic drugs. […] Medical management with topical and possibly systemic corticosteroids is usually considered the initial treatment of choice, with endoscopic sinus surgery reserved for those patients who fail to improve.

• #13 Nasal Polyps – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK560746/

  CRS affects approximately 10.9% of the European population. Prevalence estimates vary in the U.S. Around 2.1% of individuals meet the diagnostic criteria based on 2 major symptoms, while 13.0% report only 1 symptom. Among all patients with CRS, 25% to 30% are diagnosed with CRSwNP. In the U.S., CRSwNP typically presents between the ages of 40 and 60. Male individuals are more frequently affected, accounting for 62% of cases in a study, while female individuals represented 38%. Despite the lower prevalence, female patients are more likely to experience severe disease. […] This activity for healthcare professionals is designed to sharpen learners’ skills in evaluating and managing nasal polyps. Participants will deepen their understanding of the condition’s etiology, risk factors, pathophysiology, and clinical presentation. Current diagnostic and therapeutic recommendations will also be discussed. Enhanced proficiency will equip clinicians to collaborate effectively within an interprofessional team caring for affected individuals.

• #14 Nasal Polyps – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK560746/

  CRS affects approximately 10.9% of the European population. Prevalence estimates vary in the U.S. Around 2.1% of individuals meet the diagnostic criteria based on 2 major symptoms, while 13.0% report only 1 symptom. Among all patients with CRS, 25% to 30% are diagnosed with CRSwNP. In the U.S., CRSwNP typically presents between the ages of 40 and 60. Male individuals are more frequently affected, accounting for 62% of cases in a study, while female individuals represented 38%. Despite the lower prevalence, female patients are more likely to experience severe disease. […] This activity for healthcare professionals is designed to sharpen learners’ skills in evaluating and managing nasal polyps. Participants will deepen their understanding of the condition’s etiology, risk factors, pathophysiology, and clinical presentation. Current diagnostic and therapeutic recommendations will also be discussed. Enhanced proficiency will equip clinicians to collaborate effectively within an interprofessional team caring for affected individuals.

• #15 What We Know about Nasal Polyposis: The Clinician’s Point of View

  https://www.mdpi.com/2673-351X/8/2/6

  Nasal polyposis is defined as a Th2-driven chronic inflammation of the nose and sinus with polyps visible in the nasal fossae. It is a prevalent disease with a significant impact on health-related quality of life (HRQL). […] The exact prevalence of NP (nasal polyposis) in the general population is not clearly known, as epidemiological studies are missing. However, in the literature, we can find some percentages: an overall prevalence of 1% to 4% with great differences between countries ranging from 2.1% in France, 7% in Sweden, 4.3% in Finland, 1–4.2% in the USA, and 1.1–2.2% in China. […] CRS affects approximately 10–12% of the general population, although there are significant geographical variations all over the world. […] Nasal polyposis (NP) is more prevalent in men than in women, except in cases of aspirin intolerance. It predominantly affects adults after the age of 40, and its prevalence increases with age. […] Special attention is needed in the case of polyposis diagnosed in children.

• #16 Nasal Polyps – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK560746/

  CRS affects approximately 10.9% of the European population. Prevalence estimates vary in the U.S. Around 2.1% of individuals meet the diagnostic criteria based on 2 major symptoms, while 13.0% report only 1 symptom. Among all patients with CRS, 25% to 30% are diagnosed with CRSwNP. In the U.S., CRSwNP typically presents between the ages of 40 and 60. Male individuals are more frequently affected, accounting for 62% of cases in a study, while female individuals represented 38%. Despite the lower prevalence, female patients are more likely to experience severe disease. […] This activity for healthcare professionals is designed to sharpen learners’ skills in evaluating and managing nasal polyps. Participants will deepen their understanding of the condition’s etiology, risk factors, pathophysiology, and clinical presentation. Current diagnostic and therapeutic recommendations will also be discussed. Enhanced proficiency will equip clinicians to collaborate effectively within an interprofessional team caring for affected individuals.

• #17 Prevalence of Chronic Rhinosinusitis With Nasal Polyps Higher in Urban Residents, Seniors

  https://www.ajmc.com/view/prevalence-of-chronic-rhinosinusitis-with-nasal-polyps-higher-in-urban-residents-seniors

  Moreover, CRSwNP was more frequent in patients aged 55 to 59 years (98.1/10000) and 75 to 79 years (98.7/10,000). Among men, the highest prevalence was among those aged 75 to 79 years (164.3/10,000), and in women, prevalence peaked in the 55-to-59 age group (75.1/10,000). […] The NHF data in comparison with a population-wide epidemiological study show that a large proportion of patients with nasal polyps do not receive regular treatment or even do not seek medical attention, concluded the study authors.

• #18 Recorded prevalence of nasal polyps increases with age

  https://www.termedia.pl/Recorded-prevalence-of-nasal-polyps-increases-with-age,7,41897,1,1.html

  Recorded prevalence of nasal polyps increases with age. Patients with nasal polyps account for approximately 10-30% of all CRS patients. This condition typically affects middle-aged and elderly patients, average age at diagnosis is 40 to 60 years, and it is more frequent in men. The overall prevalence of nasal polyps in adults according to published epidemiological studies ranges from 1% to 4%. The recorded prevalence of CRSwNP in Poland was 52.0 per 10,000 population (64.6/10,000 for men, 40.2/10,000 for women) and varied: a) between administrative regions: from 43.1/10,000 to 62.7/10,000; b) 60.0/10,000 in cities (75.3/10,000 among men and 46.3/10,000 among women) and 39.9/10,000 in rural areas (49.1/10,000 among men and 30.7/10,000 among women). CRSwNP was much more frequent in patients aged 55-59 (98.1/10,000) and 75-79 years (98.7/10,000). Among men, the highest prevalence was in the 75-79 age group (164.3/10,000). Among women, prevalence peaked in the 55-59 age group (75.1/10,000). Nasal polyps are more than one and a half times as prevalent in men than in women. The recorded prevalence of nasal polyps increases with age and the rates peak in men aged 75-79 years and in women aged 55-59 years. Higher prevalence of CRSwNP is recorded in urban areas compared to rural areas. The NHF data in comparison with a population-wide epidemiological study shows that a large proportion of patients with nasal polyps do not receive regular treatment or even do not seek medical attention.

• #19 Epidemiology of Nasal Polyps: Ingenta Connect

  https://www.ingentaconnect.com/content/ocean/aap/1996/00000017/00000005/art00001

  Nasal polyps are found in 36% of patients with aspirin intolerance, 7% of those with asthma, 0.1% in children, and about 20% in those with cystic fibrosis. […] Nasal polyps are statistically more common in nonallergic asthma versus allergic asthma (13% vs 5%, P).

• #20 Nasal Polyps in Children: The Early Origins of a Challenging Adulthood Condition

  https://www.mdpi.com/2227-9067/8/11/997

  Nasal polyps (NPs) are benign inflammatory masses causing chronic nasal obstruction, usually associated with underlying chronic rhinosinusitis (CRS), which are rarely reported in childhood. […] In childhood, NPs usually represent red flags for systemic diseases, such as cystic fibrosis and immunodeficiencies. […] In adults, NPs occur in 1–4% of the general population, while in children, it is a fairly rare condition, with an estimated frequency of 0.1% and a significant detrimental impact on quality of life. […] Epidemiological data are scarce, and in children, most of the published studies refer to children with underlying systemic diseases. […] NP suspicion should be raised in all children with chronic nasal obstruction regardless of whether it is unilateral or bilateral or intermittent or constant.

• #21 Nasal Polyps in Children: The Early Origins of a Challenging Adulthood Condition

  https://www.mdpi.com/2227-9067/8/11/997

  Nasal polyps (NPs) are benign inflammatory masses causing chronic nasal obstruction, usually associated with underlying chronic rhinosinusitis (CRS), which are rarely reported in childhood. […] In childhood, NPs usually represent red flags for systemic diseases, such as cystic fibrosis and immunodeficiencies. […] In adults, NPs occur in 1–4% of the general population, while in children, it is a fairly rare condition, with an estimated frequency of 0.1% and a significant detrimental impact on quality of life. […] Epidemiological data are scarce, and in children, most of the published studies refer to children with underlying systemic diseases. […] NP suspicion should be raised in all children with chronic nasal obstruction regardless of whether it is unilateral or bilateral or intermittent or constant.

• #22 What We Know about Nasal Polyposis: The Clinician’s Point of View

  https://www.mdpi.com/2673-351X/8/2/6

  Nasal polyposis is defined as a Th2-driven chronic inflammation of the nose and sinus with polyps visible in the nasal fossae. It is a prevalent disease with a significant impact on health-related quality of life (HRQL). […] The exact prevalence of NP (nasal polyposis) in the general population is not clearly known, as epidemiological studies are missing. However, in the literature, we can find some percentages: an overall prevalence of 1% to 4% with great differences between countries ranging from 2.1% in France, 7% in Sweden, 4.3% in Finland, 1–4.2% in the USA, and 1.1–2.2% in China. […] CRS affects approximately 10–12% of the general population, although there are significant geographical variations all over the world. […] Nasal polyposis (NP) is more prevalent in men than in women, except in cases of aspirin intolerance. It predominantly affects adults after the age of 40, and its prevalence increases with age. […] Special attention is needed in the case of polyposis diagnosed in children.

• #23 Prevalence of Chronic Rhinosinusitis With Nasal Polyps Higher in Urban Residents, Seniors

  https://www.ajmc.com/view/prevalence-of-chronic-rhinosinusitis-with-nasal-polyps-higher-in-urban-residents-seniors

  In Poland, the prevalence of chronic rhinosinusitis with nasal polyps was shown to be greater in men, elderly individuals, and those living in urban areas. […] Greater prevalence of chronic rhinosinusitis with nasal polyps (CRSwNP) in the Polish population was associated with male gender, older age, and living in urban areas, in which inpatient services accounted for a majority of the total cost for the condition. […] Per 10,000 Polish population, the recorded prevalence of CRSwNP in 2018 was 52.0 (52%), with men exhibiting greater prevalence vs women (64.6/10,000 [0.65%] vs 40.2/10,000 [0.40%]). Prevalence was also shown to vary by geographic location, with both men and women reporting greater incidence if they lived in urban vs rural areas (men: 75.3/10,000 vs 49.1/10,000; women: 46.3/10,000 vs 30.7/10,000).

• #24 Recorded prevalence of nasal polyps increases with age

  https://www.termedia.pl/Recorded-prevalence-of-nasal-polyps-increases-with-age,7,41897,1,1.html

  Recorded prevalence of nasal polyps increases with age. Patients with nasal polyps account for approximately 10-30% of all CRS patients. This condition typically affects middle-aged and elderly patients, average age at diagnosis is 40 to 60 years, and it is more frequent in men. The overall prevalence of nasal polyps in adults according to published epidemiological studies ranges from 1% to 4%. The recorded prevalence of CRSwNP in Poland was 52.0 per 10,000 population (64.6/10,000 for men, 40.2/10,000 for women) and varied: a) between administrative regions: from 43.1/10,000 to 62.7/10,000; b) 60.0/10,000 in cities (75.3/10,000 among men and 46.3/10,000 among women) and 39.9/10,000 in rural areas (49.1/10,000 among men and 30.7/10,000 among women). CRSwNP was much more frequent in patients aged 55-59 (98.1/10,000) and 75-79 years (98.7/10,000). Among men, the highest prevalence was in the 75-79 age group (164.3/10,000). Among women, prevalence peaked in the 55-59 age group (75.1/10,000). Nasal polyps are more than one and a half times as prevalent in men than in women. The recorded prevalence of nasal polyps increases with age and the rates peak in men aged 75-79 years and in women aged 55-59 years. Higher prevalence of CRSwNP is recorded in urban areas compared to rural areas. The NHF data in comparison with a population-wide epidemiological study shows that a large proportion of patients with nasal polyps do not receive regular treatment or even do not seek medical attention.

• #25 Chronic rhinosinusitis with nasal polyposis: Management and prognosis – UpToDate

  https://www.uptodate.com/contents/chronic-rhinosinusitis-with-nasal-polyposis-management-and-prognosis

  Many patients with CRSwNP require multiple therapeutic interventions to manage their symptoms adequately and need long-term and potentially indefinite treatment. […] Patient education is critical and involves setting realistic expectations for living with a condition that usually requires indefinite treatment, ensuring that patients use optimal technique for intranasal therapies, and establishing a daily routine of sinus care to which the patient can adhere long term. […] There are several conditions that can present with CRSwNP but are important to recognize because they may impact treatment options and strategies, including aspirin-exacerbated respiratory disease (AERD), allergic rhinitis and asthma, and allergic fungal rhinosinusitis (AFRS). […] For most patients with CRSwNP, we offer sinus surgery when there is insufficient improvement with standard medical management.

• #26 The Epidemiological and Clinical Aspects of Nasal Polyps that Require Surgery

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3846212/

  The objective of this retrospective cross-sectional study was to obtain epidemiological data from the charts of 297 patients with nasal polyposis who were operated on in a referral hospital in Mashhad and to determine the frequency of the presenting symptoms of nasal polyps. […] This study highlights the need for large-scale epidemiologic research exploring the prevalence and incidence of nasal polyposis in Iran. […] Nasal polyps are mucosal lesions of the nasal or paranasal sinuses that can result from a response to inflammatory or infectious stimuli. They appear as smooth, round, semi-translucent masses that are most commonly found in the middle meatus and ethmoid sinuses and affect 1% to 4% of the population. […] The prevalence of nasal polyposis is higher in subjects with asthma than in non-asthmatics and 16.5% of asthmatic patients over 40 years of age have been shown to have nasal polyps. […] An overview of the currently available literature illustrates the paucity of accurate information on the epidemiology of nasal polyposis especially in Iran, and highlights the need for large-scale epidemiologic research exploring the prevalence and incidence of nasal polyposis.

• #27 Epidemiology of Nasal Polyps: Ingenta Connect

  https://www.ingentaconnect.com/content/ocean/aap/1996/00000017/00000005/art00001

  Nasal polyps are found in 36% of patients with aspirin intolerance, 7% of those with asthma, 0.1% in children, and about 20% in those with cystic fibrosis. […] Nasal polyps are statistically more common in nonallergic asthma versus allergic asthma (13% vs 5%, P).

• #28 Epidemiology of Nasal Polyps: Ingenta Connect

  https://www.ingentaconnect.com/content/ocean/aap/1996/00000017/00000005/art00001

  Nasal polyps are found in 36% of patients with aspirin intolerance, 7% of those with asthma, 0.1% in children, and about 20% in those with cystic fibrosis. […] Nasal polyps are statistically more common in nonallergic asthma versus allergic asthma (13% vs 5%, P).

• #29 Epidemiology of Nasal Polyps: Ingenta Connect

  https://www.ingentaconnect.com/content/ocean/aap/1996/00000017/00000005/art00001

  Nasal polyps are found in 36% of patients with aspirin intolerance, 7% of those with asthma, 0.1% in children, and about 20% in those with cystic fibrosis. […] Nasal polyps are statistically more common in nonallergic asthma versus allergic asthma (13% vs 5%, P).

• #30 Epidemiology of Nasal Polyps: Ingenta Connect

  https://www.ingentaconnect.com/content/ocean/aap/1996/00000017/00000005/art00001

  Nasal polyps are found in 36% of patients with aspirin intolerance, 7% of those with asthma, 0.1% in children, and about 20% in those with cystic fibrosis. […] Nasal polyps are statistically more common in nonallergic asthma versus allergic asthma (13% vs 5%, P).

• #31 Pediatric Nasal Polyps: Practice Essentials, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/994274-overview

  In the United States, the overall incidence of nasal polyps in children is 0.1%; the incidence in children with CF is 6-48%. Among adults, the incidence is 1-4% overall, with a range of 0.2-28%. Worldwide incidence is the same as the incidence in the United States. […] Benign multiple nasal polyposis usually manifests in patients older than 20 years and is more common in patients older than 40 years. Nasal polyps are rare in children younger than 10 years. Although the male-to-female ratio is 2-4:1 in adults, the ratio in children is unreported. A review of articles reporting on children whose nasal polyposis required surgery showed apparently equal prevalence in boys and girls, though the data are inconclusive. The reported prevalence is equal in patients with asthma. Nasal polyps occur in all races and social classes.

• #32 Nonsurgical Treatment of Nasal Polyps: Practice Essentials, Pathophysiology, Epidemiology

  https://emedicine.medscape.com/article/861353-overview

  Nasal polyps are present in 5% of nonallergic people and only 1.5% of people with allergic rhinitis. […] The prevalence is increased in patients with cystic fibrosis and aspirin-hypersensitivity triad. […] Morbidity from polyps is directly related to their location and size. […] Obstruction of the sinus ostia frequently occurs and may lead to acute or chronic sinus conditions. […] Nasal polyps are not known to be premalignant. However, they may be confused with papillomas, including inverting papillomas, which are known to be precursors of malignant lesions. […] In addition, polyps can sometimes arise from inflammation caused by malignant or premalignant nasal lesions.

• #33 Nasal polyp – Wikipedia

  https://en.wikipedia.org/wiki/Nasal_polyp

  Nasal polyps resulting from chronic rhinosinusitis affect approximately 4.3% of the population. […] Nasal polyps occur more frequently in men than women and are more common as people get older, increasing drastically after the age of 40. […] Of people with chronic rhinosinusitis, 10% to 54% also have allergies. An estimated 40% to 80% of people with sensitivity to aspirin will develop nasal polyposis. […] In people with cystic fibrosis, nasal polyps are noted in 37% to 48%.

• #34 Epidemiology of Nasal Polyposis | SpringerLink

  https://link.springer.com/chapter/10.1007/978-3-030-21217-9_42

  Nasal polyps (NP) are benign, edematous masses growing into nasal cavity that could have multiple etiological factors. […] The prevalence of NP in the general population is unclear. It varies from 0.2% to 5.6%. […] The prevalence of NP shows a wide range according to etiology. […] The most important data on the epidemiology of NP are obtained from NP etiology studies. […] There may be hereditary factors for NP but there is limited knowledge in this area. […] However, we have some evidence for genetic inheritance. Studies reported that up to 14% of patients with NP have a family history. […] A link has been indicated that NP and asthma have an association with HLA-A1B8 and HLA-A74 genes. […] The main hypotheses that lead to the development of NP will be discussed below with the current incidence and prevalence rates.

• #35 Epidemiology of Nasal Polyposis | SpringerLink

  https://link.springer.com/chapter/10.1007/978-3-030-21217-9_42

  Nasal polyps (NP) are benign, edematous masses growing into nasal cavity that could have multiple etiological factors. […] The prevalence of NP in the general population is unclear. It varies from 0.2% to 5.6%. […] The prevalence of NP shows a wide range according to etiology. […] The most important data on the epidemiology of NP are obtained from NP etiology studies. […] There may be hereditary factors for NP but there is limited knowledge in this area. […] However, we have some evidence for genetic inheritance. Studies reported that up to 14% of patients with NP have a family history. […] A link has been indicated that NP and asthma have an association with HLA-A1B8 and HLA-A74 genes. […] The main hypotheses that lead to the development of NP will be discussed below with the current incidence and prevalence rates.

• #36 The prevalence and burden of nasal polyps

  https://www.aaaai.org/tools-for-the-public/latest-research-summaries/the-journal-of-allergy-and-clinical-immunology-in/2021/burden

  Chronic rhinosinusitis with nasal polyps (CRSwNP) is a major health problem which causes a significant burden on quality of life and has a huge economic impact. Current estimates of prevalence of nasal polyposis in western settings have mostly relied on patient questionnaires and do not include the gold standard of nasal endoscopy for diagnosis. […] In a retrospective population-based study published in The Journal of Allergy and Clinical Immunology: In Practice by Campion et al., the prevalence of nasal polyps in an Austrian community-based population where more than 10,000 patients underwent endoscopic examination of their nose was investigated. […] The adjusted prevalence of nasal polyps in this central European population was found to be 1.95%. […] Interestingly, 24.8% of patients were found to have clinically silent polyps in that they did not meet the current diagnostic criteria for CRSwNP and had no wish for treatment.

• #37 Clinical Aspects of Patients with Nasal Polyposis

  https://www.arquivosdeorl.org.br/additional/acervo_eng.asp?id=625

  The nasal polyposis has a great impact on the patients’ life quality, and brings social and occupational limitations. It affects vitality and the general health, and mental health is more affected than physical health. It is estimated that the incidence in the general population is of about 1 to 4%. Without predisposition for sex, it affects preferably middle-aged people. The main complaints of the patients are usually nasal obstruction, rhinorrhea, posterior discharge, headache, hyposmia/anosmia and coughing. The nasal polyposis is a common disease in the population, with prevalence of about 4%. The mean age, at about 40 years, found in our study was similar to that of the studies by Settipane, Larsen and Drake-Lee. The patients who had asthma or AAS intolerance presented with a major affection of the paranasal sinuses, verified in tomography, which confirmed the data available in the literature. In our study, we found that the main complaint of the patient with nasal polyposis is still nasal obstruction, and most affected age is 40 years, without prevalence of sex. The severity of the tomographic findings is higher in patients who presented AAS intolerance and asthma.

• #38 Clinical Aspects of Patients with Nasal Polyposis

  http://www.arquivosdeorl.org.br/conteudo/acervo_eng.asp?Id=625

  The nasal polyposis has a great impact on the patients’ life quality, and brings social and occupational limitations. It is estimate that the incidence in the general population is of about 1 to 4% […] The main complaints of the patients are usually nasal obstruction, rhinorrhea, posterior discharge, headache, hyposmia/anosmia and coughing. […] The nasal polyposis is a common disease in the population, with prevalence of about 4%. […] The severity of the tomographic findings is higher in patients who presented AAS intolerance and asthma.

• #39 Clinical Aspects of Patients with Nasal Polyposis

  https://www.arquivosdeorl.org.br/additional/acervo_eng.asp?id=625

  The nasal polyposis has a great impact on the patients’ life quality, and brings social and occupational limitations. It affects vitality and the general health, and mental health is more affected than physical health. It is estimated that the incidence in the general population is of about 1 to 4%. Without predisposition for sex, it affects preferably middle-aged people. The main complaints of the patients are usually nasal obstruction, rhinorrhea, posterior discharge, headache, hyposmia/anosmia and coughing. The nasal polyposis is a common disease in the population, with prevalence of about 4%. The mean age, at about 40 years, found in our study was similar to that of the studies by Settipane, Larsen and Drake-Lee. The patients who had asthma or AAS intolerance presented with a major affection of the paranasal sinuses, verified in tomography, which confirmed the data available in the literature. In our study, we found that the main complaint of the patient with nasal polyposis is still nasal obstruction, and most affected age is 40 years, without prevalence of sex. The severity of the tomographic findings is higher in patients who presented AAS intolerance and asthma.

• #40 Chronic rhinosinusitis with nasal polyposis: Management and prognosis – UpToDate

  https://www.uptodate.com/contents/chronic-rhinosinusitis-with-nasal-polyposis-management-and-prognosis

  Chronic rhinosinusitis (CRS) is defined as a complex inflammatory condition involving the paranasal sinuses and linings of the nasal passages that lasts 12 weeks or longer. It is estimated to affect up to 5 percent of the population. CRS is divided into CRS with nasal polyps (CRSwNP) and CRS without NP (CRSsNP), which are distinguished by the presence or absence of nasal polyps. CRSwNP represents approximately one-third of all CRS cases. […] The disorder is associated with significant medical resource consumption and impairments in quality of life (QoL), especially during acute exacerbations. […] The management and prognosis of chronic rhinosinusitis without nasal polyps are also presented separately. […] The primary goal in treating patients with CRSwNP is to reduce sinonasal symptoms and improve quality of life (QoL) while minimizing medication adverse effects. Medical management of CRSwNP attempts to control the underlying inflammation that drives the growth of polyp tissue and the development of symptoms. Sinus surgery is used when initial medical management is not adequately effective.

• #41 Chronic Rhinosinusitis With Nasal Polyps: Prevalence, Disease Burden Investigated

  https://www.empr.com/home/mpr-first-report/aao-hns-2021/chronic-rhinosinusitis-with-nasal-polyps-prevalence-disease-burden-investigated/

  Among patients with chronic rhinosinusitis with nasal polyps (CRSwNP), younger age, elevated blood eosinophil count, and increased comorbidity were all associated with nasal polyp surgery, according to findings presented at the AAO-HNSF 2021 Annual Meeting. […] The estimated standardized prevalence of nasal polyps was reported to be 0.186% (95% CI, 0.163-0.208). Of the total 119,357 CRSwNP patients identified, 28.3% had at least 1 surgery during the observation period (median observation duration, 29.0 months). […] During follow-up, all-cause and CRSwNP-related health care resource utilization increased as the number of surgeries went up (driven by outpatient visits). Medical (hospitalizations, emergency department visits, outpatient visits, other visits) and pharmacy costs (CRSwNP-related treatment prescriptions) also increased as the number of surgeries increased.

• #42 Risk factors for recurrence of chronic rhinosinusitis with nasal polyps after endoscopic sinus surgery | Saudi Medical Journal

  https://smj.org.sa/content/44/12/1254

  Asthma is a significant risk factor for CRS recurrence. Furthermore, smoking and inadequate primary surgery increase the chance of revision surgery in case of recurrence. […] The prevalence of CRS varies widely between countries, with an overall rate of more than 10%. […] A multicenter study of 363 participants found that approximately 40% experienced recurrence of nasal polyps within 18 months after ESS. […] Recurrence of CRSwNP is associated with many risk factors, such as aspirin sensitivity, bronchial asthma, and gastroesophageal reflux disease, some of which have been identified in various studies as predisposing patients to CRS. […] Our study found that asthma, bilateral nasal polyps, high nasal polyp grade, and LM scores were associated with increased polyp recurrence in the study population.

• #43 Risk factors for recurrence of chronic rhinosinusitis with nasal polyps after endoscopic sinus surgery | Saudi Medical Journal

  https://smj.org.sa/content/44/12/1254

  Asthma is a significant risk factor for CRS recurrence. Furthermore, smoking and inadequate primary surgery increase the chance of revision surgery in case of recurrence. […] The prevalence of CRS varies widely between countries, with an overall rate of more than 10%. […] A multicenter study of 363 participants found that approximately 40% experienced recurrence of nasal polyps within 18 months after ESS. […] Recurrence of CRSwNP is associated with many risk factors, such as aspirin sensitivity, bronchial asthma, and gastroesophageal reflux disease, some of which have been identified in various studies as predisposing patients to CRS. […] Our study found that asthma, bilateral nasal polyps, high nasal polyp grade, and LM scores were associated with increased polyp recurrence in the study population.

• #44 Risk factors for recurrence of chronic rhinosinusitis with nasal polyps after endoscopic sinus surgery | Saudi Medical Journal

  https://smj.org.sa/content/44/12/1254

  Asthma is a significant risk factor for CRS recurrence. Furthermore, smoking and inadequate primary surgery increase the chance of revision surgery in case of recurrence. […] The prevalence of CRS varies widely between countries, with an overall rate of more than 10%. […] A multicenter study of 363 participants found that approximately 40% experienced recurrence of nasal polyps within 18 months after ESS. […] Recurrence of CRSwNP is associated with many risk factors, such as aspirin sensitivity, bronchial asthma, and gastroesophageal reflux disease, some of which have been identified in various studies as predisposing patients to CRS. […] Our study found that asthma, bilateral nasal polyps, high nasal polyp grade, and LM scores were associated with increased polyp recurrence in the study population.

• #45 Risk factors for recurrence of chronic rhinosinusitis with nasal polyps after endoscopic sinus surgery | Saudi Medical Journal

  https://smj.org.sa/content/44/12/1254

  Smoking is a modifiable risk factor for the recurrence of nasal polyps. […] Extensive disease with a high LM score on CT or high polyp grade on endoscopy has a well-known correlation with recurrence. […] In conclusion, our study has revealed that certain factors, such as asthma and the severity of the disease, can impact the recurrence rate of CRSwNP in the Saudi community. In addition, smoking habits and less extensive primary surgery are associated with the likelihood of needing revision surgery in cases of recurrence.

• #46 Risk factors for recurrence of chronic rhinosinusitis with nasal polyps after endoscopic sinus surgery | Saudi Medical Journal

  https://smj.org.sa/content/44/12/1254

  Smoking is a modifiable risk factor for the recurrence of nasal polyps. […] Extensive disease with a high LM score on CT or high polyp grade on endoscopy has a well-known correlation with recurrence. […] In conclusion, our study has revealed that certain factors, such as asthma and the severity of the disease, can impact the recurrence rate of CRSwNP in the Saudi community. In addition, smoking habits and less extensive primary surgery are associated with the likelihood of needing revision surgery in cases of recurrence.

• #47 Nasal Polyps in Children: The Early Origins of a Challenging Adulthood Condition

  https://www.mdpi.com/2227-9067/8/11/997

  In general, clinical manifestations depend on the size and the location of NPs, so small-sized polyps may be asymptomatic and diagnosed by chance during rhinoscopic examinations. […] Anterior rhinoscopy and paranasal sinus radiographs should be considered by now as outdated tests to diagnose NPs. Currently, the gold standard diagnostic test is nasal endoscopy, both in adults and children. […] The presence of NPs is quite a rare condition in children. Nevertheless, NPs should always be suspected in children referred for chronic nasal obstruction, either unilateral or bilateral.

• #48 Nasal Polyps in Children: The Early Origins of a Challenging Adulthood Condition

  https://www.mdpi.com/2227-9067/8/11/997

  In general, clinical manifestations depend on the size and the location of NPs, so small-sized polyps may be asymptomatic and diagnosed by chance during rhinoscopic examinations. […] Anterior rhinoscopy and paranasal sinus radiographs should be considered by now as outdated tests to diagnose NPs. Currently, the gold standard diagnostic test is nasal endoscopy, both in adults and children. […] The presence of NPs is quite a rare condition in children. Nevertheless, NPs should always be suspected in children referred for chronic nasal obstruction, either unilateral or bilateral.

• #49 Nasal Polyps in Children: The Early Origins of a Challenging Adulthood Condition

  https://www.mdpi.com/2227-9067/8/11/997

  In general, clinical manifestations depend on the size and the location of NPs, so small-sized polyps may be asymptomatic and diagnosed by chance during rhinoscopic examinations. […] Anterior rhinoscopy and paranasal sinus radiographs should be considered by now as outdated tests to diagnose NPs. Currently, the gold standard diagnostic test is nasal endoscopy, both in adults and children. […] The presence of NPs is quite a rare condition in children. Nevertheless, NPs should always be suspected in children referred for chronic nasal obstruction, either unilateral or bilateral.

• #50 Nasal Polyps in Children: The Early Origins of a Challenging Adulthood Condition

  https://www.mdpi.com/2227-9067/8/11/997

  Nasal polyps (NPs) are benign inflammatory masses causing chronic nasal obstruction, usually associated with underlying chronic rhinosinusitis (CRS), which are rarely reported in childhood. […] In childhood, NPs usually represent red flags for systemic diseases, such as cystic fibrosis and immunodeficiencies. […] In adults, NPs occur in 1–4% of the general population, while in children, it is a fairly rare condition, with an estimated frequency of 0.1% and a significant detrimental impact on quality of life. […] Epidemiological data are scarce, and in children, most of the published studies refer to children with underlying systemic diseases. […] NP suspicion should be raised in all children with chronic nasal obstruction regardless of whether it is unilateral or bilateral or intermittent or constant.

• #51 The Epidemiological and Clinical Aspects of Nasal Polyps that Require Surgery

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3846212/

  The objective of this retrospective cross-sectional study was to obtain epidemiological data from the charts of 297 patients with nasal polyposis who were operated on in a referral hospital in Mashhad and to determine the frequency of the presenting symptoms of nasal polyps. […] This study highlights the need for large-scale epidemiologic research exploring the prevalence and incidence of nasal polyposis in Iran. […] Nasal polyps are mucosal lesions of the nasal or paranasal sinuses that can result from a response to inflammatory or infectious stimuli. They appear as smooth, round, semi-translucent masses that are most commonly found in the middle meatus and ethmoid sinuses and affect 1% to 4% of the population. […] The prevalence of nasal polyposis is higher in subjects with asthma than in non-asthmatics and 16.5% of asthmatic patients over 40 years of age have been shown to have nasal polyps. […] An overview of the currently available literature illustrates the paucity of accurate information on the epidemiology of nasal polyposis especially in Iran, and highlights the need for large-scale epidemiologic research exploring the prevalence and incidence of nasal polyposis.

• #52 Prevalence of Chronic Rhinosinusitis With Nasal Polyps Higher in Urban Residents, Seniors

  https://www.ajmc.com/view/prevalence-of-chronic-rhinosinusitis-with-nasal-polyps-higher-in-urban-residents-seniors

  Moreover, CRSwNP was more frequent in patients aged 55 to 59 years (98.1/10000) and 75 to 79 years (98.7/10,000). Among men, the highest prevalence was among those aged 75 to 79 years (164.3/10,000), and in women, prevalence peaked in the 55-to-59 age group (75.1/10,000). […] The NHF data in comparison with a population-wide epidemiological study show that a large proportion of patients with nasal polyps do not receive regular treatment or even do not seek medical attention, concluded the study authors.

• #53 Recorded prevalence of nasal polyps increases with age

  https://www.termedia.pl/Recorded-prevalence-of-nasal-polyps-increases-with-age,7,41897,1,1.html

  Recorded prevalence of nasal polyps increases with age. Patients with nasal polyps account for approximately 10-30% of all CRS patients. This condition typically affects middle-aged and elderly patients, average age at diagnosis is 40 to 60 years, and it is more frequent in men. The overall prevalence of nasal polyps in adults according to published epidemiological studies ranges from 1% to 4%. The recorded prevalence of CRSwNP in Poland was 52.0 per 10,000 population (64.6/10,000 for men, 40.2/10,000 for women) and varied: a) between administrative regions: from 43.1/10,000 to 62.7/10,000; b) 60.0/10,000 in cities (75.3/10,000 among men and 46.3/10,000 among women) and 39.9/10,000 in rural areas (49.1/10,000 among men and 30.7/10,000 among women). CRSwNP was much more frequent in patients aged 55-59 (98.1/10,000) and 75-79 years (98.7/10,000). Among men, the highest prevalence was in the 75-79 age group (164.3/10,000). Among women, prevalence peaked in the 55-59 age group (75.1/10,000). Nasal polyps are more than one and a half times as prevalent in men than in women. The recorded prevalence of nasal polyps increases with age and the rates peak in men aged 75-79 years and in women aged 55-59 years. Higher prevalence of CRSwNP is recorded in urban areas compared to rural areas. The NHF data in comparison with a population-wide epidemiological study shows that a large proportion of patients with nasal polyps do not receive regular treatment or even do not seek medical attention.

• #54 Chronic Rhinosinusitis with Nasal Polyps Market to Witness Upsurge in Growth at a CAGR of 10.03% During the Study Period (2019-2032), Examines DelveInsight

  https://www.prnewswire.com/news-releases/chronic-rhinosinusitis-with-nasal-polyps-market-to-witness-upsurge-in-growth-at-a-cagr-of-10-03-during-the-study-period-20192032-examines-delveinsight-302009232.html

  The diagnosed prevalent cases of CRSwNP were further divided into Gender-specific cases. The Gender-specific diagnosed prevalent cases of CRSwNP are categorized into males and females with 1.2 million and 986K cases respectively in the US in 2022, which is expected to further increase in 2032. […] The chronic rhinosinusitis with nasal polyps market report proffers epidemiological analysis for the study period 20192032 in the 7MM segmented into: […] The dynamics of the chronic rhinosinusitis with nasal polyps are expected to change in the coming years. The disease’s increasing prevalence is likely to result in an increase in treatment choices, and as a result, the market may see an increase in the coming years. […] A significant proportion of CRSwNP patients remain undiagnosed, which may impede CRSwNP market expansion. […] In addition, the undiagnosed, unreported cases and the unawareness about the disease may also impact the CRSwNP market growth.

• #55 Chronic Rhinosinusitis with Nasal Polyps Market to Witness Upsurge in Growth at a CAGR of 10.03% During the Study Period (2019-2032), Examines DelveInsight

  https://www.prnewswire.com/news-releases/chronic-rhinosinusitis-with-nasal-polyps-market-to-witness-upsurge-in-growth-at-a-cagr-of-10-03-during-the-study-period-20192032-examines-delveinsight-302009232.html

  The diagnosed prevalent cases of CRSwNP were further divided into Gender-specific cases. The Gender-specific diagnosed prevalent cases of CRSwNP are categorized into males and females with 1.2 million and 986K cases respectively in the US in 2022, which is expected to further increase in 2032. […] The chronic rhinosinusitis with nasal polyps market report proffers epidemiological analysis for the study period 20192032 in the 7MM segmented into: […] The dynamics of the chronic rhinosinusitis with nasal polyps are expected to change in the coming years. The disease’s increasing prevalence is likely to result in an increase in treatment choices, and as a result, the market may see an increase in the coming years. […] A significant proportion of CRSwNP patients remain undiagnosed, which may impede CRSwNP market expansion. […] In addition, the undiagnosed, unreported cases and the unawareness about the disease may also impact the CRSwNP market growth.

• #56 The Epidemiological and Clinical Aspects of Nasal Polyps that Require Surgery

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3846212/

  The objective of this retrospective cross-sectional study was to obtain epidemiological data from the charts of 297 patients with nasal polyposis who were operated on in a referral hospital in Mashhad and to determine the frequency of the presenting symptoms of nasal polyps. […] This study highlights the need for large-scale epidemiologic research exploring the prevalence and incidence of nasal polyposis in Iran. […] Nasal polyps are mucosal lesions of the nasal or paranasal sinuses that can result from a response to inflammatory or infectious stimuli. They appear as smooth, round, semi-translucent masses that are most commonly found in the middle meatus and ethmoid sinuses and affect 1% to 4% of the population. […] The prevalence of nasal polyposis is higher in subjects with asthma than in non-asthmatics and 16.5% of asthmatic patients over 40 years of age have been shown to have nasal polyps. […] An overview of the currently available literature illustrates the paucity of accurate information on the epidemiology of nasal polyposis especially in Iran, and highlights the need for large-scale epidemiologic research exploring the prevalence and incidence of nasal polyposis.

• #57 The Epidemiological and Clinical Aspects of Nasal Polyps that Require Surgery

  https://ijorl.mums.ac.ir/article_207.html

  Introduction: The objective of this retrospective cross-sectional study was to obtain epidemiological data from the charts of 297 patients with nasal polyposis who were operated on in a referral hospital in Mashhad and to determine the frequency of the presenting symptoms of nasal polyps. […] Conclusion: This study highlights the need for large-scale epidemiologic research exploring the prevalence and incidence of nasal polyposis in Iran.

• #58 Epidemiology of Nasal Polyposis | SpringerLink

  https://link.springer.com/chapter/10.1007/978-3-030-21217-9_42

  Nasal polyps (NP) are benign, edematous masses growing into nasal cavity that could have multiple etiological factors. […] The prevalence of NP in the general population is unclear. It varies from 0.2% to 5.6%. […] The prevalence of NP shows a wide range according to etiology. […] The most important data on the epidemiology of NP are obtained from NP etiology studies. […] There may be hereditary factors for NP but there is limited knowledge in this area. […] However, we have some evidence for genetic inheritance. Studies reported that up to 14% of patients with NP have a family history. […] A link has been indicated that NP and asthma have an association with HLA-A1B8 and HLA-A74 genes. […] The main hypotheses that lead to the development of NP will be discussed below with the current incidence and prevalence rates.

• #59 Epidemiology and differential diagnosis of nasal polyps – ScienceOpen

  https://www.scienceopen.com/document?vid=a5a789bd-f4a6-44fc-abae-f1cf50fbc220

  Chronic rhinosinusitis (CRS) is one of the most common chronic medical conditions, with a significant impact on patient quality of life. […] This study provides a review of the epidemiology and major classification of CRSwNP. […] Many definitions of CRSwNP exist and estimates of prevalence vary. […] CRSwNP is a clinical syndrome with a heterogeneous inflammatory profile. Of the subtypes associated with eosinophilic inflammation, AERD remains the most recalcitrant to medical and surgical therapeutic interventions.

• #60 The prevalence and burden of nasal polyps

  https://www.aaaai.org/tools-for-the-public/latest-research-summaries/the-journal-of-allergy-and-clinical-immunology-in/2021/burden

  After adapting the currently available guidelines on the use of biologics in nasal polyps it was found that between 6 and 13% of patients with nasal polyps would be eligible for biological therapy. […] This study is the first to highlight that in a community-based population a significant proportion of nasal polyps are asymptomatic and do not require treatment. It is also the first to estimate the number of patients who would, according to current guidelines, be eligible for newly available biological therapies.

• #61 Chronic Rhinosinusitis with Nasal Polyps Market to Witness Upsurge in Growth at a CAGR of 10.03% During the Study Period (2019-2032), Examines DelveInsight

  https://www.prnewswire.com/news-releases/chronic-rhinosinusitis-with-nasal-polyps-market-to-witness-upsurge-in-growth-at-a-cagr-of-10-03-during-the-study-period-20192032-examines-delveinsight-302009232.html

  The diagnosed prevalent cases of CRSwNP were further divided into Gender-specific cases. The Gender-specific diagnosed prevalent cases of CRSwNP are categorized into males and females with 1.2 million and 986K cases respectively in the US in 2022, which is expected to further increase in 2032. […] The chronic rhinosinusitis with nasal polyps market report proffers epidemiological analysis for the study period 20192032 in the 7MM segmented into: […] The dynamics of the chronic rhinosinusitis with nasal polyps are expected to change in the coming years. The disease’s increasing prevalence is likely to result in an increase in treatment choices, and as a result, the market may see an increase in the coming years. […] A significant proportion of CRSwNP patients remain undiagnosed, which may impede CRSwNP market expansion. […] In addition, the undiagnosed, unreported cases and the unawareness about the disease may also impact the CRSwNP market growth.

• #62 Chronic Rhinosinusitis with Nasal Polyps – Epidemiology Forecast – 2034

  https://www.researchandmarkets.com/reports/5525160/chronic-rhinosinusitis-with-nasal-polyps?srsltid=AfmBOooBKXWK3ouPmzoSWux92fG6oc0X-Mf0KBEgFMg6K-27CXUW-PbG

  As per the analysis CRSwNP accounted for approximately 4.38 million cases in the 7MM in 2022. […] The overall count of individuals diagnosed with CRSwNP in the United States was nearly 2.19 million in 2022, and it is expected to increase at an estimated CAGR throughout the study period (2020-2034). […] Among the 7MM, EU4 and the UK accounted for approx. 1.98 million diagnosed prevalent cases of CRSwNP, and these cases are expected to increase during the forecast period (2023-2034). […] Gender-specific diagnosed prevalent cases of CRSwNP showed that males (60%) were more affected by CRSwNP than females (40%) in the EU4 and the UK in 2022.

• #63 Chronic Rhinosinusitis with Nasal Polyps – Epidemiology Forecast – 2034

  https://www.researchandmarkets.com/reports/5525160/chronic-rhinosinusitis-with-nasal-polyps?srsltid=AfmBOooBKXWK3ouPmzoSWux92fG6oc0X-Mf0KBEgFMg6K-27CXUW-PbG

  As per the analysis CRSwNP accounted for approximately 4.38 million cases in the 7MM in 2022. […] The overall count of individuals diagnosed with CRSwNP in the United States was nearly 2.19 million in 2022, and it is expected to increase at an estimated CAGR throughout the study period (2020-2034). […] Among the 7MM, EU4 and the UK accounted for approx. 1.98 million diagnosed prevalent cases of CRSwNP, and these cases are expected to increase during the forecast period (2023-2034). […] Gender-specific diagnosed prevalent cases of CRSwNP showed that males (60%) were more affected by CRSwNP than females (40%) in the EU4 and the UK in 2022.

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