Materiały źródłowe

• #1 Erectile Dysfunction – StatPearls – NCBI BookshelfTwitterFacebookLinkedInGitHubNCBI Insights BlogTwitterFacebookYoutube

  https://www.ncbi.nlm.nih.gov/books/NBK562253/

  Erectile dysfunction (ED) is a prevalent and multifaceted condition that predominantly afflicts males beyond 40 years, with its prevalence escalating globally. […] The best available data indicate that 52% of men in the US between 40 and 70 years of age have erectile dysfunction. […] Further, it is estimated that at least 30 to 50 million men in the US and at least 150 million men globally have ED. […] The prevalence of ED is closely related to age and the presence of other co-morbidities such as diabetes, hypogonadism, and cardiovascular disease. […] Estimates suggest that erectile dysfunction will affect 322 million men worldwide by 2025.

• #1 (PDF) Erectile Dysfunction – Epidemiology, management and prevention

  https://www.academia.edu/17046389/Erectile_Dysfunction_Epidemiology_management_and_prevention

  Erectile dysfunction (ED) or male impotence is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis. […] Until about 20 years ago erectile dysfunction was thought to be almost entirely caused by psychological factors but it is now known that physical conditions are present in about 75% of sufferers and that in many men it may be caused by a combination of both. […] Erectile dysfunction (ED), assessed clinically by tools such as the International Index of Erectile Function (IIEF), affects millions of men across the world. Around 10-25% of men of all ages are affected rising to 20-45% in older age groups. […] Ageing populations in the developed world and growing populations in the developing world make it likely that the prevalence of ED will increase in the future.

• #1 Frontiers | A comprehensive analysis of erectile dysfunction prevalence and the impact of prostate conditions on ED among US adults: evidence from NHANES 2001-2004

  https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1412369/full

  The study established BPH and PCa as significant risk factors for ED, with no substantial link detected between prostatitis and ED. This finding highlights the necessity for tailored screening and management protocols for individuals with BPH and PCa to mitigate the burden of ED. […] The prevalence of ED varies across continents. In North America, particularly the United States, the prevalence of ED is well-documented. The Massachusetts Male Aging Study (MMAS) reported that approximately 52% of men aged 40-70 experience some degree of ED. In Europe, the prevalence of ED is similar to that in North America. The European Male Aging Study (EMAS) found that about 19% of men aged 40-79 experience moderate to severe ED, with prevalence increasing with age. […] Clinical research on ED has seen rapid advancement in recent years. Previous epidemiological studies have shown a significant correlation between the presence of prostate-related health issues and increased incidence of ED. Prostate diseases such as BPH and prostate cancer are among the most common medical conditions in aging men.

• #1 WHO EMRO | Prevalence and risk factors of erectile dysfunction among patients attending primary health care centres in Qatar | Volume 17, issue 7 | EMHJ volume 17, 2011WHO EMRO | Prevalence and risk factors of erectile dysfunction among patients attending

  https://www.emro.who.int/emhj-volume-17/volume-17-issue-7/article6.html

  The prevalence of erectile dysfunction varies widely in studies from different countries. It was estimated to be 18.4% in men aged ≥ 20 years in the United States, 49.4% in Canada and 63.6% in Hong Kong. In a study in Qatar the prevalence of erectile dysfunction among Qatari patients was 66.2% among hypertensive patients and 23.8% among non-hypertensive controls. […] The high prevalence of erectile dysfunction among men attending PHC centres in Qatar is a concern. Health policy-makers need to consider including training of health personnel to consider the relevant risk factors during the physical, social and psychological diagnosis of different age and ethnic groups.

• #1 Epidemiology of ED » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/physicianinformation/epidemiology-of-ed/

  Erectile dysfunction is a significant and common medical problem. Recent epidemiologic studies suggest that approximately 10% of men aged 40-70 have severe or complete erectile dysfunction, defined as the total inability to achieve or maintain erections sufficient for sexual performance. An additional 25% of men in this age category have moderate or intermittent erectile difficulties. The disorder is highly age-dependent, as the combined prevalence of moderate to complete erectile dysfunction rises from approximately 22% at age 40 to 49% by age 70. […] Findings from these studies show that erectile dysfunction impacts significantly on mood state, interpersonal functioning, and overall quality of life. […] Erectile dysfunction is strongly related to both physical and psychological health. Among the major risk factors are diabetes mellitus, heart disease, hypertension and decreased HDL levels. […] The psychological correlates of erectile dysfunction include anxiety, depression and anger. Despite its increasing prevalence among older men, erectile dysfunction is not considered a normal or inevitable part of the aging process.

• #1 Erectile Dysfunction | 5-Minute Clinical Consult

  https://www.unboundmedicine.com/5minute/view/5-Minute-Clinical-Consult/116215/all/Erectile_Dysfunction

  Erectile dysfunction (ED): the consistent or recurrent inability to acquire and/or sustain an erection of sufficient rigidity and duration for sexual intercourse. […] Incidence>600,000 new cases of ED diagnosed annually in the United States; ED is vastly underreported. PrevalenceOverall prevalence for some degree of ED: 52% in men aged 40 to 70 years. […] Age-related increase ranging from 12.4% in men aged 40 to 49 years up to 46.6% in men aged 50 to 69 years.

• #1 Epidemiology of ED » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/patientinformation-physicians/epidemiology-of-ed/

  Erectile dysfunction (ED) is a significant and common medical problem. […] Approximately 10% of men aged 40-70 have severe or complete erectile dysfunction, defined as the total inability to achieve or maintain erections sufficient for sexual performance. […] The disorder is highly age-dependent, as the combined prevalence of moderate to complete erectile dysfunction rises from approximately 22% at age 40 to 49% by age 70. […] Although less common in younger men, erectile dysfunction still affects 5%-10% of men below the age of 40. […] Findings from these studies show that erectile dysfunction impacts significantly on mood state, interpersonal functioning, and overall quality of life. […] Erectile dysfunction is strongly related to both physical and psychological health. […] Among the major risk factors are diabetes mellitus, heart disease, hypertension and decreased HDL levels.

• #1 Epidemiology of ED » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/physicianinformation/epidemiology-of-ed/

  The association between vascular disease and erectile dysfunction has been recognized and well documented. Indeed, alterations in the vascular hemodynamics (whether, arterial insufficiency or corporovenocclusive dysfunction) is believed to be the most common cause of organic erectile dysfunction. […] Myocardial infarction (MI) and coronary artery bypass surgery have been associated with erectile difficulties in 64% and 57% respectively. […] Diabetes with its related vasculopathy is associated with a higher incidence of impotence at all ages compared to the general population. The prevalence of impotence in all-comer diabetics has been variably estimated at between 35 and 75%. […] The incidence of impotence in diabetics is age-dependent and is higher in men with juvenile-onset diabetes compared to adult-onset diabetics.

• #1 Epidemiology of ED » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/physicianinformation/epidemiology-of-ed/

  As the number of vascular risk factors (such as, cigarette smoking, hypertension, cardiac disease, hyperlipidemia, and diabetes) increases so too does the likelihood of erectile dysfunction. […] This finding was confirmed in Virag’s analysis of 400 impotent men, demonstrating that 80% of these men had physiologic abnormalities and that vascular risk factors were more common in this group compared to the general population. […] While androgens are essential to the growth and differentiation of the male genital tract, the development of secondary sexual characteristics and the presence of libido their role in the erectile process remains unclear. […] Nevertheless, endocrinopathies probably account for up between 3-6% of all organic erectile dysfunction and those endocrinopathies that may lead to impotence include hypogonadism, hypothyroidism, hyperthyroidism, hyperprolactinemia, diabetes mellitus, adrenal disorders, chronic liver disease, chronic renal failure and AIDS.

• #1 Frontiers | A comprehensive analysis of erectile dysfunction prevalence and the impact of prostate conditions on ED among US adults: evidence from NHANES 2001-2004

  https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1412369/full

  A comprehensive analysis of erectile dysfunction prevalence and the impact of prostate conditions on ED among US adults: evidence from NHANES 2001-2004 […] Erectile dysfunction (ED) is characterized by the inability to achieve or maintain penile erection sufficient for intercourse. While previous research suggests a potential link between ED and prostate pathologies, the association between benign prostatic hyperplasia (BPH), prostatitis, prostatic cancer (PCa), and ED remains to be elucidated. […] Among the 2225 participants, the weighted prevalence of ED was 27.47%, with 16.17% in the 40-60 years age group and 56.98% in the 60-80 years age group. BPH had an ED prevalence of 47.57%, prostatitis 34.62%, and PCa 85.62%. Multivariate logistic regression analysis identified BPH as an independent risk factor for ED in the 60-80 years age group (OR=1.93; 95% CI, 1.18-3.18, P=0.02), and PCa was positively associated with ED in both the 40-60 years group (OR=11.90; 95% CI, 1.41-100.50, P=0.03) and the 40-80 years group (OR=7.30; 95% CI, 2.12-25.08, P=0.01).

• #1 Epidemiology of ED » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/physicianinformation/epidemiology-of-ed/

  Drug associated erectile dysfunction is common and the list of medications that can induce erectile dysfunction is significant. […] Medication-induced impotence has been estimated occurring in up to 25% of patients in a medical outpatient clinic. […] Pelvic trauma, in particular injuries to the perineum and pelvic fractures, are associated with erectile dysfunction. […] Furthermore, the pathophysiologic mechanisms for the development of such impotence has been previously postulated. […] Urologic surgery of a variety of types has been implicated in erectile dysfunction. […] The operations that have been reported to cause erectile dysfunction include, radical prostatectomy, retropubic and perineal, whether nerve-sparing or not, TURP, internal urethrotomy, perineal urethroplasty and pelvic exenterative procedures. […] Until 15 years ago impotence was believed to be the result of psychological issues in the majority of men. […] In the MMAS, psychologic factors associated with erectile problems included depression, anger and low levels of dominance.

• #1 Epidemiology of Erectile Dysfunction | SpringerLink

  https://link.springer.com/chapter/10.1007/978-1-59745-155-0_2

  Erectile dysfunction (ED) is a highly prevalent condition among men all over world. […] Its prevalence and incidence are associated with aging as well as important comorbidities, such as cardiovascular disease, diabetes, metabolic syndrome, hyperlipidemia, depression, pelvic surgery, side effects of medications, neurological disorders, trauma, symptoms of benign prostate hyperplasia, and psychological and interpersonal problems. […] Recent studies have revealed that ED is not a correlate of cardiovascular disease, diabetes, and metabolic syndrome; it is rather early warning symptom. […] Studies on treatment-seeking behavior revealed significant barriers to seeking treatment for this condition and its important correlates. […] Braun M, Wassmer G, Klotz T, et al. Epidemiology of erectile dysfunction: results of the Cologne male survey. Int J Impot Res 2000; 12: 305–311. […] Nicolosi A, Moreira ED Jr, Shirai M, Bin Mohd Tambi MI, Glasser DB. Epidemiology of erectile dysfunction in four countries: cross-national study of the prevalence and correlates of erectile dysfunction. Urology 2003; 61: 201.

• #1 1 in 5 men surveyed had erectile dysfunction up to 2 years after COVID | CIDRAPUniversity of Minnesota

  https://www.cidrap.umn.edu/covid-19/1-5-men-surveyed-had-erectile-dysfunction-2-years-after-covid

  A total of 19.0% of 609 men who completed a survey in Japan and had persistent COVID symptoms reported erectile dysfunction (ED) 1 and/or 2 years post-infection, perhaps due to depression, anxiety, and/or sleep disturbances, suggest researchers with the COVID-19 Recovery Study II Group. […] The group conducted a case-control study based on a survey fielded 1 and 2 years post-infection about ED and underlying factors among 609 men aged 20 years and older admitted to 1 of 20 hospitals for COVID-19 from March to September 2021, a period spanning the Alpha and Delta variants. […] „In COVID-19 patients, vascular endothelial damage due to inflammatory cytokines and hypoxia in the acute phase of COVID-19 lead to the progression of ED,” the investigators wrote. „Furthermore, ED is affected by physical stress and psychological stress.”

• #1 Frontiers | Dietary metal intake and the prevalence of erectile dysfunction in US men: Results from National Health and Nutrition Examination Survey 2001–2004

  https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.974443/full

  Erectile dysfunction (ED) mainly affects men over 40 years of age and is a common clinical condition. […] The National Institutes of Health (NIH) defines erectile dysfunction as the inability to maintain a sufficient penile erection over the course of a sexual relationship. […] Incidence of ED gradually increases with age. […] The prevalence of ED in men less than 40 years of age is 1–10%. However, it increases to 20–40% in men aged 60–69 years, and ranges from 50 to 100% in those over 70 years. […] As the world’s population ages, the prevalence of ED will be even higher, with 322 million cases expected by 2025. […] Several studies have shown that ED is closely related to hypertension, diabetes, hyperlipidemia, and neurological disorders. […] Currently, the number of studies on the relationship between dietary nutritional intake and ED prevalence are limited.

• #1 JMIR Public Health and Surveillance – Associations Between Online Pornography Consumption and Sexual Dysfunction in Young Men: Multivariate Analysis Based on an International Web-Based Survey

  https://publichealth.jmir.org/2021/10/e32542/

  According to their IIEF-5 scores, 21.48% (444/2067) of our sexually active participants (ie, those who attempted penetrative sex in the previous 4 weeks) had some degree of ED. […] The prevalence of ED in young men is alarmingly high, and the results of this study suggest a significant association with PPC. […] Getting an erection is, of course, a process that requires the neurological, hormonal, and circulatory systems to work together. Inability to get or maintain an erection can be due to penile (vascular or neurological) problems or to more centralized issues (eg, depression, lack of desire, anxiety), but these conventional components cannot entirely explain the higher prevalence of ED in young men. […] The following results are based on the participants who attempted sexual intercourse during the past 4 weeks (2067/3419).

• #1 (PDF) Erectile Dysfunction – Epidemiology, management and prevention

  https://www.academia.edu/17046389/Erectile_Dysfunction_Epidemiology_management_and_prevention

  The condition remains a source of embarrassment for many men and health professionals, and it remains under-reported, under-recognized, and undertreated. […] Erectile dysfunction (ED) is a pervasive problem among men worldwide. […] Recent data from a longitudinal analysis of the Massachusetts Male Aging Study (MMAS) estimated that up to 600,000 new cases of ED occur annually in the United States. […] This is in addition to a prevalence estimated to be 10 to 20 million American men. […] According to a survey, the Massachusetts Male Aging Study, 52% of men beyond 40 years of age may have some degrees of erectile failure, and it is projected to affect 322 million men worldwide by 2025. […] It is been estimated that about 35-75% of men with diabetes will experience at least some degree of erectile dysfunction during their lifetime. […] As men with diabetes age, erectile dysfunction becomes even more common.

• #1 Epidemiology of ED » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/physicianinformation/epidemiology-of-ed/

  Conservative estimates of its incidence have been made at between 10-20 million men. Furthermore, it has been shown that erectile problems account for 400,000 out-patient physician visits, 30,000 hospital admissions and an annual financial outlay by our health industry of 146 million dollars. […] The Massachusetts Male Aging Study (MMAS) was a cross-sectional, community-based, random-sample, multidisciplinary epidemiologic survey of aging and health in men aged 40-70 years. […] The overall rate of any degree of impotence the MMAS was 52%, including 17% minimally impotent, 25% moderately impotent and 10% completely impotent. The overall probability of impotence, of any degree, at 40 years was 39% and at 70 years 67%. Extrapolating these data, there would be 30 million men in the United States with some form of erectile impairment.

• #1 Epidemiology and Diagnosis of Erectile Dysfunction by Urologists Versus Non-Urologists in the United States: An Analysis of the National Ambulatory Medical Care Survey.

  https://vivo.weill.cornell.edu/display/pubid32979379

  OBJECTIVES: To evaluate the extent to which erectile dysfunction (ED) is managed by urologists versus non-urologists. We sought to characterize the epidemiology, diagnosis, and outpatient treatment of ED using a nationally representative cohort. […] RESULTS: Among the 170,499 patient visits analyzed, 1.2% were associated with a diagnosis of ED, which translated into 3,409,244 weighted visits annually. […] CONCLUSION: Almost half of all ED visits were seen by non-urologist providers, who were much less likely than urologists to order advanced pharmacologic therapies. This difference in prescribing patterns presents an opportunity for interdisciplinary collaboration and education to ensure that all patients seeking treatment for ED are receiving guideline-based care.

• #1 Erectile Dysfunction: Epidemiology and Etiology

  https://www.urology-textbook.com/erectile-dysfunction.html

  Erectile dysfunction (ED) is the inadequacy of erection for at least six months duration, which prevents satisfactory sexual intercourse in more than 70%. […] The prevalence of erectile dysfunction rises with age. In the Massachusetts male aging study (MMAS), the prevalence rate of ED was 8% (40–49 years), 16% (50–59 years), and 37% (60–69 years) (Johannes et al., 2000). […] In Germany, a pronounced age dependency is also observed. But, despite the rising prevalence with age, there is a high sexual activity in each age group (96–71%). The prevalence of erectile dysfunction is 2% (30–39 years), 10% (40–49 years), 16% (50–59 years), 34% (60–69 years), 53% (70–79 years). Overall, the prevalence was 19%, but only 7% were dissatisfied with their sexuality and wanted a treatment (Braun et al., 2000).

• #1 Erectile dysfunction in fit and healthy young men: psychological or pathological? – Rastrelli – Translational Andrology and UrologyErectile dysfunction in fit and healthy young men: psychological or pathological?

  https://tau.amegroups.org/article/view/12327/13814

  According to these data, ED in younger men, although still not extensively studied and largely overlooked by the scientific community, is a quite common condition. […] In a recent study conducted in a Urology Clinic, it has been observed that one out of four men seeking medical care for ED was younger than 40 years. […] According to these data, ED is becoming a common concern even among young men, and the clinical practitioner in sexual medicine must become aware of how to manage the problem and avoid underestimating a symptom. […] The identification of ED in a young man may potentially provide a great deal of useful information that can help improve their quality and even length of life. […] These findings demonstrate the importance of recognizing a possible organic component of ED even in younger men.

• #1 Erectile dysfunction in fit and healthy young men: psychological or pathological? – Rastrelli – Translational Andrology and UrologyErectile dysfunction in fit and healthy young men: psychological or pathological?

  https://tau.amegroups.org/article/view/12327/13814

  Once observed that the organic component of ED is the most important one in younger patients, the summarized evidence underlines that metabolic and CV risk must not be underestimated in younger men even when they are apparently healthy. […] In fact, it is particularly in these men that recognizing the presence of risk factors can help in changing life-style, thus really changing the natural history of metabolic and CV diseases. […] ED is a symptom that can provide a chance for both the patients and physicians to unearth the presence of CV risk factors and improve both the quality and length of life of these men.

• #2 Epidemiology of ED » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/physicianinformation/epidemiology-of-ed/

  Erectile dysfunction is a significant and common medical problem. Recent epidemiologic studies suggest that approximately 10% of men aged 40-70 have severe or complete erectile dysfunction, defined as the total inability to achieve or maintain erections sufficient for sexual performance. An additional 25% of men in this age category have moderate or intermittent erectile difficulties. The disorder is highly age-dependent, as the combined prevalence of moderate to complete erectile dysfunction rises from approximately 22% at age 40 to 49% by age 70. […] Findings from these studies show that erectile dysfunction impacts significantly on mood state, interpersonal functioning, and overall quality of life. […] Erectile dysfunction is strongly related to both physical and psychological health. Among the major risk factors are diabetes mellitus, heart disease, hypertension and decreased HDL levels. […] The psychological correlates of erectile dysfunction include anxiety, depression and anger. Despite its increasing prevalence among older men, erectile dysfunction is not considered a normal or inevitable part of the aging process.

• #2 Epidemiology of ED » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/patientinformation-physicians/epidemiology-of-ed/

  Erectile dysfunction (ED) is a significant and common medical problem. […] Approximately 10% of men aged 40-70 have severe or complete erectile dysfunction, defined as the total inability to achieve or maintain erections sufficient for sexual performance. […] The disorder is highly age-dependent, as the combined prevalence of moderate to complete erectile dysfunction rises from approximately 22% at age 40 to 49% by age 70. […] Although less common in younger men, erectile dysfunction still affects 5%-10% of men below the age of 40. […] Findings from these studies show that erectile dysfunction impacts significantly on mood state, interpersonal functioning, and overall quality of life. […] Erectile dysfunction is strongly related to both physical and psychological health. […] Among the major risk factors are diabetes mellitus, heart disease, hypertension and decreased HDL levels.

• #2 The global burden of erectile dysfunction and its associated risk factors in diabetic patients: an umbrella reviews | BMC Public Health | Full Text

  https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-024-20300-7

  Erectile dysfunction is no longer a whisper in the shadows; it’s a rising tide threatening the sexual health of millions of men in different regions. […] This worrying trend shows no signs of slowing down, with projections claiming a staggering 322 million men globally could be affected in the near future. […] Thus, this umbrella review intended to estimate the current burden of erectile dysfunction and associated risk factors among diabetic patients in the global context. […] In this umbrella review, a total of 108 030 male diabetic patients were included to estimate the global prevalence of erectile dysfunction. The pooled global prevalence of erectile dysfunction in diabetic patients was 65.8% (95CI: 58.3 –73.3%), while In Africa it was 62.9% (95CI: 46.1–79.7). […] The high global prevalence of erectile dysfunction (ED) in diabetic patients is alarming, with an estimated two-thirds experiencing the condition. […] This includes promoting early screening for erectile dysfunction in this population and ensuring access to appropriate treatment and support.

• #2 WHO EMRO | Prevalence and risk factors of erectile dysfunction among patients attending primary health care centres in Qatar | Volume 17, issue 7 | EMHJ volume 17, 2011WHO EMRO | Prevalence and risk factors of erectile dysfunction among patients attending

  https://www.emro.who.int/emhj-volume-17/volume-17-issue-7/article6.html

  The prevalence of erectile dysfunction varies widely in studies from different countries. It was estimated to be 18.4% in men aged ≥ 20 years in the United States, 49.4% in Canada and 63.6% in Hong Kong. In a study in Qatar the prevalence of erectile dysfunction among Qatari patients was 66.2% among hypertensive patients and 23.8% among non-hypertensive controls. […] The high prevalence of erectile dysfunction among men attending PHC centres in Qatar is a concern. Health policy-makers need to consider including training of health personnel to consider the relevant risk factors during the physical, social and psychological diagnosis of different age and ethnic groups.

• #2 Epidemiology of erectile dysfunction: results of the ‘Cologne Male Survey’ | International Journal of Impotence Research

  https://www.nature.com/articles/3900622

  The last few decades have seen a marked increase in mean life expectancy in Central Europe. […] Available data from the United States and Scandinavia relating to erectile dysfunction (ED) do not enable us to draw valid conclusions about the current situation in Germany. The aim of the present study was to evaluate the epidemiology of male sexuality in Germany, and the proportion of men who need medical treatment because of increased suffering from this. […] The prevalence of ED was 19.2%, with a steep age-related increase (2.3–53.4%) and a high co-morbidity of ED with hypertension, diabetes, pelvic surgery and ‘lower urinary tract symptoms’. […] We conclude that regular sexual activity is a normal finding in advanced age. ED is a frequent disorder, contributing to dissatisfaction with sex life in a considerable proportion of men. The high burden of ED is reflected in willingness to pay for treatment. ED is frequently associated with chronic diseases. Therefore adequate diagnostic workup is essential, to offer patients individually adapted treatment. General non-reimbursability of treatment for ED appears to be unacceptable.

• #2 Erectile Dysfunction: Epidemiology and Etiology

  https://www.urology-textbook.com/erectile-dysfunction.html

  Erectile dysfunction (ED) is the inadequacy of erection for at least six months duration, which prevents satisfactory sexual intercourse in more than 70%. […] The prevalence of erectile dysfunction rises with age. In the Massachusetts male aging study (MMAS), the prevalence rate of ED was 8% (40–49 years), 16% (50–59 years), and 37% (60–69 years) (Johannes et al., 2000). […] In Germany, a pronounced age dependency is also observed. But, despite the rising prevalence with age, there is a high sexual activity in each age group (96–71%). The prevalence of erectile dysfunction is 2% (30–39 years), 10% (40–49 years), 16% (50–59 years), 34% (60–69 years), 53% (70–79 years). Overall, the prevalence was 19%, but only 7% were dissatisfied with their sexuality and wanted a treatment (Braun et al., 2000).

• #2 Erectile dysfunction in fit and healthy young men: psychological or pathological? – Rastrelli – Translational Andrology and UrologyErectile dysfunction in fit and healthy young men: psychological or pathological?

  https://tau.amegroups.org/article/view/12327/html

  According to these data, ED in younger men, although still not extensively studied and largely overlooked by the scientific community, is a quite common condition. […] In a recent study conducted in a Urology Clinic, it has been observed that one out of four men seeking medical care for ED was younger than 40 years. […] According to these data, ED is becoming a common concern even among young men, and the clinical practitioner in sexual medicine must become aware of how to manage the problem and avoid underestimating a symptom. […] The identification of ED in a young man may potentially provide a great deal of useful information that can help improve their quality and even length of life. […] In summary, in subjects with ED, T is the only hormone whose measurement is recommended. […] Therefore, T deficiency must be accurately verified in all subjects consulting for sexual dysfunction, even in the youngest ones.

• #2 Epidemiology of erectile dysfunction | Endocrine

  https://link.springer.com/article/10.1385/ENDO:23:2-3:087

  Following the landmark Massachusetts Male Aging Study (MMAS) that provided the first relatively unbiased study of the epidemiology of erectile dysfunction (ED), a number of additional studies were carried out in the U.S. and around the world. […] The studies demonstrated similar levels of ED by age and an exponential rise with age. […] They also generally confirmed the conditions that correlated with ED in the MMAS, namely, diabetes, hypertension, coronary artery disease, prostate cancer therapy, and depression. These were exacerbated by cigaret smoking.

• #2 Erectile Dysfunction | AAFP

  https://www.aafp.org/pubs/afp/issues/2016/1115/p820.html

  Erectile dysfunction (ED) is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. ED becomes more common as men age. At least 12 million U.S. men 40 to 79 years of age have ED. […] ED has vascular, neurologic, psychological, and hormonal causes. Conditions commonly associated with ED include diabetes mellitus, hypertension, hyperlipidemia, obesity, testosterone deficiency, and prostate cancer treatment. […] Patients with diabetes are three times more likely to develop ED, and a longer duration of diabetes is strongly associated with ED. Metabolic syndrome is associated with a 2.6-fold increase in the incidence of ED, and the fasting blood glucose level is the component associated with the highest risk of ED. […] ED and CVD share similar risk factors, including older age, hypertension, dyslipidemia, smoking, obesity, and diabetes. ED is associated with an increased risk of CVD, coronary artery disease (CAD), stroke, and all-cause mortality, and it is probably an independent risk factor for CVD. […] Management of cardiovascular risk factors is recommended in men who have ED but no known CVD. Because diagnosing ED can help identify men at higher risk of CVD, use of the IIEF-5 is also recommended during CVD risk assessment.

• #2 Epidemiology of ED » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/patientinformation-physicians/epidemiology-of-ed/

  The prevalence of ED in all diabetics has been estimated between 35 and 75%. […] Erectile difficulties may be the harbinger of diabetes, ED occurs in 12% of newly diagnosed diabetics. […] Drug associated erectile dysfunction is common and the list of medications that can induce erectile dysfunction is significant. […] Medication-induced impotence has been estimated occurring in up to 25% of patients in a medical outpatient clinic. […] Antihypertensive agents are associated with erectile difficulties, depending upon the specific agents in 4-40% of patients. […] Pelvic trauma, in particular injuries to the perineum and pelvic fractures, are associated with erectile dysfunction.

• #2 Frontiers | A comprehensive analysis of erectile dysfunction prevalence and the impact of prostate conditions on ED among US adults: evidence from NHANES 2001-2004

  https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1412369/full

  The study established BPH and PCa as significant risk factors for ED, with no substantial link detected between prostatitis and ED. This finding highlights the necessity for tailored screening and management protocols for individuals with BPH and PCa to mitigate the burden of ED. […] The prevalence of ED varies across continents. In North America, particularly the United States, the prevalence of ED is well-documented. The Massachusetts Male Aging Study (MMAS) reported that approximately 52% of men aged 40-70 experience some degree of ED. In Europe, the prevalence of ED is similar to that in North America. The European Male Aging Study (EMAS) found that about 19% of men aged 40-79 experience moderate to severe ED, with prevalence increasing with age. […] Clinical research on ED has seen rapid advancement in recent years. Previous epidemiological studies have shown a significant correlation between the presence of prostate-related health issues and increased incidence of ED. Prostate diseases such as BPH and prostate cancer are among the most common medical conditions in aging men.

• #2 Epidemiology of ED » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/physicianinformation/epidemiology-of-ed/

  Drug associated erectile dysfunction is common and the list of medications that can induce erectile dysfunction is significant. […] Medication-induced impotence has been estimated occurring in up to 25% of patients in a medical outpatient clinic. […] Pelvic trauma, in particular injuries to the perineum and pelvic fractures, are associated with erectile dysfunction. […] Furthermore, the pathophysiologic mechanisms for the development of such impotence has been previously postulated. […] Urologic surgery of a variety of types has been implicated in erectile dysfunction. […] The operations that have been reported to cause erectile dysfunction include, radical prostatectomy, retropubic and perineal, whether nerve-sparing or not, TURP, internal urethrotomy, perineal urethroplasty and pelvic exenterative procedures. […] Until 15 years ago impotence was believed to be the result of psychological issues in the majority of men. […] In the MMAS, psychologic factors associated with erectile problems included depression, anger and low levels of dominance.

• #2 1 in 5 men surveyed had erectile dysfunction up to 2 years after COVID | CIDRAPUniversity of Minnesota

  https://www.cidrap.umn.edu/covid-19/1-5-men-surveyed-had-erectile-dysfunction-2-years-after-covid

  In total, 116 men (19.0%) reported having ED, including 86 in the 1-year survey, 70 in the 2-year survey, and 40 in both. […] Anxiety, depression, and sleep disturbances after the post-acute phase of COVID-19 infection suggest that supportive care for the symptoms and quality of life is expected for ED as Long-COVID. […] Seventy-nine (68.1%) men said they developed ED within 28 days of COVID-19 infection, and 6 (4.3%) did so 2 to 5 months following infection. […] Of the 116 men with ED, 29 (25.0%) experienced ED improvement during the study. […] Fifty-seven patients (49.1%) still had ED at 2 years. An exploratory clustering analysis suggested that ED was related to disturbed sleep, while COVID-19 severity, reinfection, vaccination frequency, and antiviral treatment were unrelated. […] „Anxiety, depression, and sleep disturbances after the post-acute phase of COVID-19 infection suggest that supportive care for the symptoms and quality of life is expected for ED as Long-COVID,” the study authors wrote.

• #2 Frontiers | Dietary metal intake and the prevalence of erectile dysfunction in US men: Results from National Health and Nutrition Examination Survey 2001–2004

  https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.974443/full

  The aim of this study was to investigate the relationship between dietary trace metal intake and erectile dysfunction. […] The results showed that dietary intake of magnesium, zinc, copper, and selenium was significantly lower in ED patients than participants without ED. […] Dose-response curve analysis of the RCS also found a negative correlation between dietary trace metal intake (magnesium, zinc, copper, and selenium) and ED prevalence. […] Interestingly, in the subgroup analysis, dietary metal intake was not significantly associated with ED prevalence in participants younger than 40 years. […] This suggests that dietary trace metal intake primarily affects ED prevalence in men over 40 years of age. […] Increasing dietary metal intake significantly reduced the OR of ED. […] Increasing dietary intake of trace metals (magnesium, zinc, copper, and selenium) within the upper limit is beneficial in reducing the prevalence of ED.

• #2 JMIR Public Health and Surveillance – Associations Between Online Pornography Consumption and Sexual Dysfunction in Young Men: Multivariate Analysis Based on an International Web-Based Survey

  https://publichealth.jmir.org/2021/10/e32542/

  Higher CYPAT scores indicating problematic online pornography consumption resulted in a higher probability of ED, while controlling for covariates. […] There was a statistically significant correlation between ED and CYPAT (P<.001). Higher CYPAT categories were associated with a higher prevalence of ED. [...] The prevalence of ED in young men is alarmingly high, and the results of this study suggest a significant association with PPC.

• #2 Erectile dysfunction prevalence in the United States: report from the 2021 National Survey of Sexual Wellbeing

  https://pubmed.ncbi.nlm.nih.gov/38410029/

  There has been a great deal of public speculation regarding a surge in erectile dysfunction (ED) in younger men despite data consistently indicating that the ED prevalence rates increase with age. […] In this study we sought to assess the prevalence and risk of experiencing ED in a nationally representative sample of men in the United States across various social groups, describe comorbidities, and examine barriers to treatment. […] The ED prevalence rate based on IIEF-5 scores was 24.2%. Prevalence increased with age: 52.2% of the 75+ age group, and 48.0% of the 65-74 age group meeting diagnostic criteria for ED. […] The results indicate that ED prevalence and severity remain highest in older age groups and that most individuals who meet criteria for ED have not sought medical care related to this concern.

• #2 Erectile dysfunction in fit and healthy young men: psychological or pathological? – Rastrelli – Translational Andrology and UrologyErectile dysfunction in fit and healthy young men: psychological or pathological?

  https://tau.amegroups.org/article/view/12327/13814

  Once observed that the organic component of ED is the most important one in younger patients, the summarized evidence underlines that metabolic and CV risk must not be underestimated in younger men even when they are apparently healthy. […] In fact, it is particularly in these men that recognizing the presence of risk factors can help in changing life-style, thus really changing the natural history of metabolic and CV diseases. […] ED is a symptom that can provide a chance for both the patients and physicians to unearth the presence of CV risk factors and improve both the quality and length of life of these men.

• #3 Epidemiology of ED » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/physicianinformation/epidemiology-of-ed/

  Conservative estimates of its incidence have been made at between 10-20 million men. Furthermore, it has been shown that erectile problems account for 400,000 out-patient physician visits, 30,000 hospital admissions and an annual financial outlay by our health industry of 146 million dollars. […] The Massachusetts Male Aging Study (MMAS) was a cross-sectional, community-based, random-sample, multidisciplinary epidemiologic survey of aging and health in men aged 40-70 years. […] The overall rate of any degree of impotence the MMAS was 52%, including 17% minimally impotent, 25% moderately impotent and 10% completely impotent. The overall probability of impotence, of any degree, at 40 years was 39% and at 70 years 67%. Extrapolating these data, there would be 30 million men in the United States with some form of erectile impairment.

• #3 (PDF) Erectile Dysfunction – Epidemiology, management and prevention

  https://www.academia.edu/17046389/Erectile_Dysfunction_Epidemiology_management_and_prevention

  The condition remains a source of embarrassment for many men and health professionals, and it remains under-reported, under-recognized, and undertreated. […] Erectile dysfunction (ED) is a pervasive problem among men worldwide. […] Recent data from a longitudinal analysis of the Massachusetts Male Aging Study (MMAS) estimated that up to 600,000 new cases of ED occur annually in the United States. […] This is in addition to a prevalence estimated to be 10 to 20 million American men. […] According to a survey, the Massachusetts Male Aging Study, 52% of men beyond 40 years of age may have some degrees of erectile failure, and it is projected to affect 322 million men worldwide by 2025. […] It is been estimated that about 35-75% of men with diabetes will experience at least some degree of erectile dysfunction during their lifetime. […] As men with diabetes age, erectile dysfunction becomes even more common.

• #3 Erectile Dysfunction: Epidemiology and Etiology

  https://www.urology-textbook.com/erectile-dysfunction.html

  Erectile dysfunction (ED) is the inadequacy of erection for at least six months duration, which prevents satisfactory sexual intercourse in more than 70%. […] The prevalence of erectile dysfunction rises with age. In the Massachusetts male aging study (MMAS), the prevalence rate of ED was 8% (40–49 years), 16% (50–59 years), and 37% (60–69 years) (Johannes et al., 2000). […] In Germany, a pronounced age dependency is also observed. But, despite the rising prevalence with age, there is a high sexual activity in each age group (96–71%). The prevalence of erectile dysfunction is 2% (30–39 years), 10% (40–49 years), 16% (50–59 years), 34% (60–69 years), 53% (70–79 years). Overall, the prevalence was 19%, but only 7% were dissatisfied with their sexuality and wanted a treatment (Braun et al., 2000).

• #3 Frontiers | Dietary metal intake and the prevalence of erectile dysfunction in US men: Results from National Health and Nutrition Examination Survey 2001–2004

  https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2022.974443/full

  Erectile dysfunction (ED) mainly affects men over 40 years of age and is a common clinical condition. […] The National Institutes of Health (NIH) defines erectile dysfunction as the inability to maintain a sufficient penile erection over the course of a sexual relationship. […] Incidence of ED gradually increases with age. […] The prevalence of ED in men less than 40 years of age is 1–10%. However, it increases to 20–40% in men aged 60–69 years, and ranges from 50 to 100% in those over 70 years. […] As the world’s population ages, the prevalence of ED will be even higher, with 322 million cases expected by 2025. […] Several studies have shown that ED is closely related to hypertension, diabetes, hyperlipidemia, and neurological disorders. […] Currently, the number of studies on the relationship between dietary nutritional intake and ED prevalence are limited.

• #3 Erectile Dysfunction | AAFP

  https://www.aafp.org/pubs/afp/issues/2016/1115/p820.html

  Erectile dysfunction (ED) is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. ED becomes more common as men age. At least 12 million U.S. men 40 to 79 years of age have ED. […] ED has vascular, neurologic, psychological, and hormonal causes. Conditions commonly associated with ED include diabetes mellitus, hypertension, hyperlipidemia, obesity, testosterone deficiency, and prostate cancer treatment. […] Patients with diabetes are three times more likely to develop ED, and a longer duration of diabetes is strongly associated with ED. Metabolic syndrome is associated with a 2.6-fold increase in the incidence of ED, and the fasting blood glucose level is the component associated with the highest risk of ED. […] ED and CVD share similar risk factors, including older age, hypertension, dyslipidemia, smoking, obesity, and diabetes. ED is associated with an increased risk of CVD, coronary artery disease (CAD), stroke, and all-cause mortality, and it is probably an independent risk factor for CVD. […] Management of cardiovascular risk factors is recommended in men who have ED but no known CVD. Because diagnosing ED can help identify men at higher risk of CVD, use of the IIEF-5 is also recommended during CVD risk assessment.

• #3 Epidemiology of ED » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/physicianinformation/epidemiology-of-ed/

  Drug associated erectile dysfunction is common and the list of medications that can induce erectile dysfunction is significant. […] Medication-induced impotence has been estimated occurring in up to 25% of patients in a medical outpatient clinic. […] Pelvic trauma, in particular injuries to the perineum and pelvic fractures, are associated with erectile dysfunction. […] Furthermore, the pathophysiologic mechanisms for the development of such impotence has been previously postulated. […] Urologic surgery of a variety of types has been implicated in erectile dysfunction. […] The operations that have been reported to cause erectile dysfunction include, radical prostatectomy, retropubic and perineal, whether nerve-sparing or not, TURP, internal urethrotomy, perineal urethroplasty and pelvic exenterative procedures. […] Until 15 years ago impotence was believed to be the result of psychological issues in the majority of men. […] In the MMAS, psychologic factors associated with erectile problems included depression, anger and low levels of dominance.

• #3 Epidemiology and Diagnosis of Erectile Dysfunction by Urologists Versus Non-Urologists in the United States: An Analysis of the National Ambulatory Medical Care Survey.

  https://vivo.weill.cornell.edu/display/pubid32979379

  OBJECTIVES: To evaluate the extent to which erectile dysfunction (ED) is managed by urologists versus non-urologists. We sought to characterize the epidemiology, diagnosis, and outpatient treatment of ED using a nationally representative cohort. […] RESULTS: Among the 170,499 patient visits analyzed, 1.2% were associated with a diagnosis of ED, which translated into 3,409,244 weighted visits annually. […] CONCLUSION: Almost half of all ED visits were seen by non-urologist providers, who were much less likely than urologists to order advanced pharmacologic therapies. This difference in prescribing patterns presents an opportunity for interdisciplinary collaboration and education to ensure that all patients seeking treatment for ED are receiving guideline-based care.

• #4 Erectile Dysfunction – StatPearls – NCBI BookshelfTwitterFacebookLinkedInGitHubNCBI Insights BlogTwitterFacebookYoutube

  https://www.ncbi.nlm.nih.gov/books/NBK562253/

  Erectile dysfunction (ED) is a prevalent and multifaceted condition that predominantly afflicts males beyond 40 years, with its prevalence escalating globally. […] The best available data indicate that 52% of men in the US between 40 and 70 years of age have erectile dysfunction. […] Further, it is estimated that at least 30 to 50 million men in the US and at least 150 million men globally have ED. […] The prevalence of ED is closely related to age and the presence of other co-morbidities such as diabetes, hypogonadism, and cardiovascular disease. […] Estimates suggest that erectile dysfunction will affect 322 million men worldwide by 2025.

• #4 Epidemiology of erectile dysfunction: A… | F1000Research

  https://f1000research.com/articles/8-817

  Erectile dysfunction (ED) is principally defined as the inability to reach and maintain an adequate erection to achieve satisfying sexual intercourse. Many epidemiological studies have demonstrated high prevalence of ED in different parts of the world. The objective of the present study was to establish the prevalence of ED in a healthy population from Indonesia and risk factors associated with ED. The prevalence of ED was 35.6% (22.3% mild, 13.7% mild to moderate, 3.1% moderate and 0.8% severe). The prevalence of ED ranges from 6.5% in the 20-29 year old group, to as high as 88.0% in respondents aged 60 years old and above. Age, hypertension, stroke, history of heart disease, diabetes, kidney disease, history of prostate operations and interpersonal stress are significantly associated with ED (p-value = <0.001, <0.001, 0.015 0.000, 0.01, 0.002, <0.001 and 0.022 respectively). [...] The prevalence of ED in this study ranges from 6.5% to as high as 88.0%. Age, hypertension, stroke, history of heart disease, diabetes, kidney disease, history of prostate operation and interpersonal stress are significantly associated with ED.

• #4 The global burden of erectile dysfunction and its associated risk factors in diabetic patients: an umbrella reviews | BMC Public Health | Full Text

  https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-024-20300-7

  By 2025, an estimated 322 million men will have ED, underscoring its critical public health impact. […] Among diabetic patients, ED prevalence ranges from 35 to 90%. […] Erectile dysfunction (ED) is a common complication of diabetes, affecting millions of men worldwide. […] Thus, understanding erectile dysfunction among diabetic patients in a global context can have contribute to improving the health and well-being of diabetic patients worldwide. […] The global prevalence of erectile dysfunction in diabetic patients is 65.8% (95CI: 58.3 –73.3%). […] Age (>40 years), DM duration (>10 years), peripheral vascular disease, and BMI (>30 kg/m2) were identified as associated risk factors of erectile dysfunction in diabetic patients.

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