Zapalenie cewki moczowej
Leczenie
Zapalenie cewki moczowej (urethritis) wymaga celowanego leczenia antybiotykowego, dostosowanego do etiologii zakażenia. W przypadku rzeżączkowego zapalenia cewki moczowej (GU) zaleca się ceftriakson 500 mg domięśniowo w pojedynczej dawce (1 g u pacjentów ≥150 kg) lub cefiksym 800 mg doustnie, a w przypadku alergii na cefalosporyny gentamycynę 240 mg domięśniowo plus azytromycynę 2 g doustnie. Leczenie nierzeżączkowego zapalenia cewki moczowej (NGU) opiera się na doksycyklinie 100 mg doustnie 2 razy dziennie przez 7 dni lub azytromycynie 1 g jednorazowo. W zakażeniach Mycoplasma genitalium stosuje się dwuetapową terapię: doksycyklinę 100 mg 2x/dobę przez 7 dni, a następnie azytromycynę lub moksyfloksacynę 400 mg przez 7 dni, w zależności od dostępności testów oporności. W przypadku Trichomonas vaginalis rekomendowany jest metronidazol lub tynidazol 2 g doustnie jednorazowo. Leczenie wirusowego zapalenia cewki moczowej (HSV) obejmuje acyklowir, famcyklowir lub walacyklowir.
- Leczenie zapalenia cewki moczowej
- Farmakoterapia bakteryjnego zapalenia cewki moczowej
- Leczenie zakażeń wywołanych przez Mycoplasma genitalium
- Leczenie innych zakażeń wywołujących zapalenie cewki moczowej
- Leczenie przetrwałego lub nawracającego zapalenia cewki moczowej
- Leczenie nieinfekcyjnego zapalenia cewki moczowej
- Leczenie objawowe
- Postępowanie z partnerami seksualnymi
- Zalecenia dotyczące aktywności seksualnej podczas leczenia
- Monitorowanie i kontrola po leczeniu
- Skuteczność i rezultaty leczenia
- Wybór odpowiedniego schematu leczenia
- Podsumowanie kluczowych zaleceń w leczeniu zapalenia cewki moczowej
Leczenie zapalenia cewki moczowej
Zapalenie cewki moczowej (urethritis) to stan zapalny cewki moczowej wymagający odpowiedniego leczenia w celu zapobiegania powikłaniom oraz rozprzestrzenianiu się infekcji. Leczenie powinno być ukierunkowane na wyeliminowanie czynnika przyczynowego, złagodzenie objawów oraz zapobieganie nawrotom choroby12.
Farmakoterapia bakteryjnego zapalenia cewki moczowej
Antybiotyki stanowią podstawę leczenia zapalenia cewki moczowej o etiologii bakteryjnej. Wybór antybiotyku powinien uwzględniać skuteczność, działania niepożądane, koszty oraz compliance pacjenta1. W większości przypadków optymalne jest leczenie pojedynczą dawką antybiotyku podaną w gabinecie lekarskim2.
Leczenie powinno obejmować zarówno rzeżączkowe (GU), jak i nierzeżączkowe zapalenie cewki moczowej (NGU), chyba że jeden z tych czynników został wykluczony badaniami diagnostycznymi3. Lekarz może rozpocząć antybiotykoterapię jeszcze przed otrzymaniem wyników badań, jeśli podejrzewa infekcję45.
Leczenie rzeżączkowego zapalenia cewki moczowej
W przypadku rzeżączkowego zapalenia cewki moczowej, Centers for Disease Control and Prevention (CDC) obecnie zaleca:67
- Ceftriakson 500 mg domięśniowo w pojedynczej dawce (1 g domięśniowo u pacjentów ważących ≥150 kg)
- Jeśli ceftriakson jest niedostępny, podaje się cefiksym 800 mg doustnie w pojedynczej dawce
- W przypadku alergii na cefalosporyny lub reakcji nadwrażliwości typu 1 na penicyliny, można zastosować gentamycynę 240 mg domięśniowo plus azytromycynę 2 g doustnie
- Jeśli infekcja chlamydiowa nie została wykluczona, należy dodatkowo zastosować doksycyklinę 100 mg doustnie dwa razy dziennie przez 7 dni8
Leczenie nierzeżączkowego zapalenia cewki moczowej
Dla leczenia nierzeżączkowego zapalenia cewki moczowej (NGU) CDC zaleca:910
- Doksycyklina 100 mg doustnie dwa razy dziennie przez 7 dni (leczenie pierwszego wyboru)
- Alternatywnie: azytromycyna 1 g doustnie w pojedynczej dawce lub 500 mg doustnie w pierwszej dawce, a następnie 250 mg doustnie raz dziennie przez 4 dni11
Doksycyklina jest wysoce skuteczna w leczeniu zakażeń cewki moczowej wywoływanych przez Chlamydia trachomatis, a także wykazuje skuteczność w zakażeniach odbytnicy oraz posiada pewną aktywność przeciwko Mycoplasma genitalium12.
Leczenie zakażeń wywołanych przez Mycoplasma genitalium
Mycoplasma genitalium jest związana z objawami zapalenia cewki moczowej i odpowiada za 15-25% przypadków NGU w Stanach Zjednoczonych13. Zakażenia tym drobnoustrojem są szczególnie istotne w przypadku nawracającego lub przetrwałego zapalenia cewki moczowej14.
CDC zaleca dwuetapowe podejście do leczenia zakażenia M. genitalium:1516
- Jeśli dostępne jest badanie oporności M. genitalium, należy je wykonać i wykorzystać wyniki do ukierunkowania terapii
- W przypadku zakażenia M. genitalium wrażliwego na makrolidy: doksycyklina 100 mg doustnie 2 razy/dobę przez 7 dni, a następnie azytromycyna 1 g doustnie dawka początkowa, następnie 500 mg doustnie dziennie przez 3 dodatkowe dni (łącznie 2,5 g)17
- Jeśli badanie oporności M. genitalium nie jest dostępne: doksycyklina 100 mg doustnie 2 razy/dobę przez 7 dni, a następnie moksyfloksacyna 400 mg doustnie raz dziennie przez 7 dni1819
Leczenie innych zakażeń wywołujących zapalenie cewki moczowej
W przypadku zakażenia Trichomonas vaginalis, które powinno być brane pod uwagę u heteroseksualnych pacjentów z utrzymującymi się objawami, zaleca się:20
- Metronidazol 2 g doustnie w pojedynczej dawce lub
- Tynidazol 2 g doustnie w pojedynczej dawce21
W przypadku zapalenia cewki moczowej wywołanego przez wirusa opryszczki pospolitej (HSV), leczenie obejmuje:22
- Acyklowir (Zovirax)
- Famcyklowir (Famvir)
- Walacyklowir (Valtrex)23
Leczenie przetrwałego lub nawracającego zapalenia cewki moczowej
Pacjenci z utrzymującymi się lub nawracającymi objawami powinni zostać poddani ponownej ocenie24. Pierwszym krokiem w przypadku nawracającego zapalenia cewki moczowej jest ocena przestrzegania zaleceń leczniczych lub potencjalnego ponownego narażenia na kontakt z nieleczonym partnerem seksualnym25.
W przypadku przetrwałego lub nawracającego NGU, najczęstszym czynnikiem jest Mycoplasma genitalium, szczególnie po leczeniu doksycykliną26. Jeśli T. vaginalis jest mało prawdopodobny, mężczyźni z nawracającym NGU powinni zostać przebadani w kierunku M. genitalium przy użyciu zatwierdzonych przez FDA testów amplifikacji kwasów nukleinowych (NAAT)27.
Zapalenie cewki moczowej, które nie ustępuje po 6 tygodniach leczenia antybiotykami, nazywane jest przewlekłym zapaleniem cewki moczowej. W takim przypadku mogą być konieczne inne antybiotyki28.
Leczenie nieinfekcyjnego zapalenia cewki moczowej
Jeśli zapalenie cewki moczowej jest spowodowane tarciem lub stosowaniem drażniących substancji chemicznych, takich jak mydło lub środki plemnikobójcze, lekarz może zalecić:2930
- Zaprzestanie noszenia obcisłej odzieży
- Unikanie substancji drażniących
- Ograniczenie czasu spędzanego na wykonywaniu czynności powodujących tarcie31
W przypadku zapalenia cewki moczowej spowodowanego urazem lub drażniącymi substancjami chemicznymi nie jest wymagane specyficzne leczenie. Lekarz może przepisać fenazopirydynę (Pyridium) w celu złagodzenia pieczenia lub bólu podczas oddawania moczu32.
Leczenie objawowe
Oprócz leczenia przyczynowego, w celu złagodzenia objawów można zastosować:33
- Niesteroidowe leki przeciwzapalne (NLPZ), takie jak naproksen, w celu złagodzenia bólu
- Fenazopirydynę, która może zmniejszyć potrzebę oddawania moczu i częstotliwość mikcji3435
Postępowanie z partnerami seksualnymi
Skuteczne leczenie zapalenia cewki moczowej wymaga również odpowiedniego postępowania z partnerami seksualnymi pacjenta:3637
- Partnerzy seksualni z ostatnich 60 dni przed wystąpieniem objawów powinni zostać przebadani i leczeni
- Leczenie partnerów seksualnych zapobiega ponownemu zakażeniu pacjenta oraz rozprzestrzenianiu się infekcji
- Jeśli tylko jeden z partnerów jest leczony, infekcja może być przekazywana z powrotem3839
W niektórych przypadkach zalecana jest przyspieszona terapia partnerska (expedited partner therapy), polegająca na przepisaniu leczenia partnerom seksualnym pacjentów z nowo zdiagnozowaną chlamydiozą lub rzeżączką bez badania partnera. Jest to legalne w większości stanów USA40.
Zalecenia dotyczące aktywności seksualnej podczas leczenia
Aby zminimalizować transmisję i ponowne zakażenia, pacjenci leczeni na zapalenie cewki moczowej powinni:4142
- Powstrzymać się od kontaktów seksualnych przez 7 dni po rozpoczęciu leczenia
- Czekać, aż oni i ich partnerzy zakończą leczenie
- Wstrzymać się od aktywności seksualnej do czasu ustąpienia objawów4344
Monitorowanie i kontrola po leczeniu
Po zakończeniu leczenia istotne jest monitorowanie skuteczności terapii:45
- Pacjent może zostać poproszony o powrót na wizytę kontrolną po 1-2 tygodniach w celu sprawdzenia skuteczności leczenia
- Objawy zwykle ustępują w ciągu kilku dni od rozpoczęcia leczenia, ale ważne jest, aby ukończyć całą zaleconą kurację antybiotykową4647
- W przypadku utrzymywania się objawów po zakończeniu leczenia, pacjent powinien wrócić do lekarza w celu ponownej oceny48
Test kontrolny (test of cure) nie jest zalecany, jeśli jest wykonywany wcześniej niż 3 tygodnie po zakończeniu leczenia rzeżączki lub chlamydiozy, ponieważ testy NAAT mogą dawać fałszywie dodatnie wyniki w tym okresie49.
Skuteczność i rezultaty leczenia
Przy odpowiednim leczeniu rokowanie w zapaleniu cewki moczowej jest zwykle dobre:5051
- Objawy zapalenia cewki moczowej zwykle ustępują samoistnie w czasie, niezależnie od leczenia, ale podawanie antybiotyków ma na celu zapobieganie powikłaniom i ograniczenie przenoszenia infekcji na innych5253
- W przypadku prawidłowego leczenia zapalenie cewki moczowej jest całkowicie uleczalne54
- Objawy zwykle ustępują w ciągu tygodnia lub dwóch od rozpoczęcia leczenia5556
Nieleczone zapalenie cewki moczowej może prowadzić do poważnych powikłań, w tym do uszkodzenia cewki moczowej i innych części układu moczowego57.
Wybór odpowiedniego schematu leczenia
Wybór schematu leczenia powinien uwzględniać lokalną oporność na antybiotyki, potencjalne interakcje z innymi lekami oraz indywidualne cechy pacjenta58. W tabeli poniżej przedstawiono najczęściej stosowane antybiotyki w leczeniu zapalenia cewki moczowej:
| Antybiotyk | Dawkowanie | Wskazania |
|---|---|---|
| Ceftriakson (Rocephin) | 500 mg domięśniowo jednorazowo (1 g u pacjentów ≥150 kg) | Rzeżączkowe zapalenie cewki moczowej |
| Cefiksym (Suprax) | 800 mg doustnie jednorazowo | Alternatywa dla ceftriaksonu w rzeżączkowym zapaleniu cewki moczowej |
| Doksycyklina (Vibramycin) | 100 mg doustnie 2 razy dziennie przez 7 dni | Nierzeżączkowe zapalenie cewki moczowej, zakażenia Chlamydia |
| Azytromycyna (Zithromax) | 1 g doustnie jednorazowo lub 500 mg, następnie 250 mg przez 4 dni | Alternatywa dla doksycykliny, zakażenia Mycoplasma genitalium |
| Moksyfloksacyna | 400 mg doustnie raz dziennie przez 7-14 dni | Mycoplasma genitalium oporna na makrolidy |
| Metronidazol (Flagyl) | 2 g doustnie jednorazowo | Zakażenia Trichomonas vaginalis |
| Tynidazol (Tindamax) | 2 g doustnie jednorazowo | Alternatywa dla metronidazolu w zakażeniach Trichomonas vaginalis |
| Erytromycyna | 500 mg doustnie 4 razy dziennie przez 7 dni | Alternatywa w przypadku nietolerancji innych antybiotyków |
| Ofloksacyna | 300 mg doustnie 2 razy dziennie przez 7 dni | Alternatywa w przypadku nietolerancji innych antybiotyków |
| Lewofloksacyna | 500 mg doustnie raz dziennie przez 7 dni | Alternatywa w przypadku nietolerancji innych antybiotyków |
Podsumowanie kluczowych zaleceń w leczeniu zapalenia cewki moczowej
Skuteczne leczenie zapalenia cewki moczowej wymaga kompleksowego podejścia:59
- Stosowanie odpowiednich antybiotyków w zależności od czynnika etiologicznego
- Ukończenie pełnej zaleconej kuracji antybiotykowej, nawet jeśli objawy ustąpią wcześniej
- Testowanie i leczenie partnerów seksualnych
- Powstrzymanie się od aktywności seksualnej do czasu zakończenia leczenia i ustąpienia objawów
- Wizyty kontrolne w celu potwierdzenia skuteczności leczenia
- W przypadku utrzymywania się objawów – ponowna ocena i diagnostyka w kierunku innych patogenów6061
Cele leczenia zapalenia cewki moczowej obejmują łagodzenie objawów, zapobieganie powikłaniom u pacjenta i jego partnerów seksualnych, zmniejszenie transmisji współistniejących zakażeń (szczególnie HIV), identyfikację i leczenie kontaktów pacjenta oraz zachęcanie do zmian behawioralnych, które zmniejszą ryzyko nawrotu62.
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Materiały źródłowe
- #1 Urethritis Treatmentshttps://www.urologists.org/article/treatments/urethritis-treatments
Urethritis is the swelling and irritation of the tube that transports urine from the bladder (urethra). Treatment for urethritis involves dealing with the underlying cause, which can include infections as well as injury or trauma. […] Many cases of urethritis are caused by infections, such as sexually-transmitted infections (STIs) such as chlamydia or gonorrhea. Treatment for this type of urethritis involves: Eliminating the infection, Providing relief from symptoms, Preventing transmission of the infection to sexual partners, Encouraging less risky behavior to prevent recurrence of infection, Identifying and treating sexual partners. […] Antibiotics, such as azithromycin (Zithromax) or cefixime (Suprax) can treat the underlying infection. When applicable, a patient’s partner must also be treated for the same infection.
- #1 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
Symptoms of urethritis typically resolve spontaneously over time, regardless of treatment. Administer antibiotics to prevent morbidity and to reduce disease transmission to others. Treating recent sexual contacts (those having sexual contact with the patient within 60 days prior to symptom onset) also prevents reinfection of the index patient. […] Antibiotic therapy for urethritis should cover both gonococcal urethritis (GU) and nongonococcal urethritis (NGU). The choice of antibiotics should be based on effectiveness, adverse effects, cost, and compliance. In most situations, optimal treatment is with single-dose therapy administered in the emergency department or the physician’s office. […] Currently, the CDC recommends a single dose of ceftriaxone 500 mg IM (1 g IM in patients weighing 150 kg) for the treatment of GU. If ceftriaxone is unavailable, administer cefixime 800 mg orally in a single dose. If the patient has a cephalosporin allergy or a type 1 hypersensitivity reaction to penicillins, treat with gentamicin 240 mg IM plus azithromycin, 2 g orally. If chlamydial infection has not been excluded, treatment should also include doxycycline, 100 mg orally twice a day for 7 days.
- #2 Urethritis: MedlinePlus Medical EncyclopediaLockhttps://medlineplus.gov/ency/article/000439.htm
The goals of treatment are to: […] If you have a bacterial infection, you will be given antibiotics. […] You may take both pain relievers for general body pain and products for localized urinary tract pain, plus antibiotics. […] People with urethritis who are being treated should avoid sex, or use condoms during sex. Your sexual partner must also be treated if the condition is caused by an infection. […] Urethritis caused by trauma or chemical irritants is treated by avoiding the source of injury or irritation. […] Urethritis that does not clear up after antibiotic treatment and lasts for at least 6 weeks is called chronic urethritis. Different antibiotics may be used to treat this problem.
- #2 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
Symptoms of urethritis typically resolve spontaneously over time, regardless of treatment. Administer antibiotics to prevent morbidity and to reduce disease transmission to others. Treating recent sexual contacts (those having sexual contact with the patient within 60 days prior to symptom onset) also prevents reinfection of the index patient. […] Antibiotic therapy for urethritis should cover both gonococcal urethritis (GU) and nongonococcal urethritis (NGU). The choice of antibiotics should be based on effectiveness, adverse effects, cost, and compliance. In most situations, optimal treatment is with single-dose therapy administered in the emergency department or the physician’s office. […] Currently, the CDC recommends a single dose of ceftriaxone 500 mg IM (1 g IM in patients weighing 150 kg) for the treatment of GU. If ceftriaxone is unavailable, administer cefixime 800 mg orally in a single dose. If the patient has a cephalosporin allergy or a type 1 hypersensitivity reaction to penicillins, treat with gentamicin 240 mg IM plus azithromycin, 2 g orally. If chlamydial infection has not been excluded, treatment should also include doxycycline, 100 mg orally twice a day for 7 days.
- #3 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
Symptoms of urethritis typically resolve spontaneously over time, regardless of treatment. Administer antibiotics to prevent morbidity and to reduce disease transmission to others. Treating recent sexual contacts (those having sexual contact with the patient within 60 days prior to symptom onset) also prevents reinfection of the index patient. […] Antibiotic therapy for urethritis should cover both gonococcal urethritis (GU) and nongonococcal urethritis (NGU). The choice of antibiotics should be based on effectiveness, adverse effects, cost, and compliance. In most situations, optimal treatment is with single-dose therapy administered in the emergency department or the physician’s office. […] Currently, the CDC recommends a single dose of ceftriaxone 500 mg IM (1 g IM in patients weighing 150 kg) for the treatment of GU. If ceftriaxone is unavailable, administer cefixime 800 mg orally in a single dose. If the patient has a cephalosporin allergy or a type 1 hypersensitivity reaction to penicillins, treat with gentamicin 240 mg IM plus azithromycin, 2 g orally. If chlamydial infection has not been excluded, treatment should also include doxycycline, 100 mg orally twice a day for 7 days.
- #4 Urethritis: Causes, Symptoms, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/22858-urethritis
Antibiotics are the standard treatment. […] Antibiotics are the main treatment for urethritis, either alone or in combination. Some of the antibiotics used to treat urethritis include: Azithromycin, Doxycycline, Ofloxacin, Levofloxacin, Ceftriaxone, Cefixime. […] Your provider may start you on antibiotics even before getting results back if they believe you have an infection. […] If you have urethritis from friction or from using irritating chemicals like soap or spermicide, your provider will suggest that you stop wearing tight clothing, stop using the irritant and cut back on the time you spend doing the activity that causes friction. […] Make sure to take all of your antibiotics as instructed by your healthcare provider. Usually, you’ll need to take the medications for a week to 10 days. You’ll probably begin to feel better after a few days, but it’s important to make sure that you take the entire prescription. […] If you have urethritis and you’re treated with the correct medication, you should be cured entirely. It’s important to note that your sexual partners must also take the medication. If only one of you is treated, you can continue to pass the infection back and forth. […] Urethritis can be cured.
- #5 Urethritis Treatmentshttps://www.urologists.org/article/treatments/urethritis-treatments
Urethritis is the swelling and irritation of the tube that transports urine from the bladder (urethra). Treatment for urethritis involves dealing with the underlying cause, which can include infections as well as injury or trauma. […] Many cases of urethritis are caused by infections, such as sexually-transmitted infections (STIs) such as chlamydia or gonorrhea. Treatment for this type of urethritis involves: Eliminating the infection, Providing relief from symptoms, Preventing transmission of the infection to sexual partners, Encouraging less risky behavior to prevent recurrence of infection, Identifying and treating sexual partners. […] Antibiotics, such as azithromycin (Zithromax) or cefixime (Suprax) can treat the underlying infection. When applicable, a patient’s partner must also be treated for the same infection.
- #6 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
Symptoms of urethritis typically resolve spontaneously over time, regardless of treatment. Administer antibiotics to prevent morbidity and to reduce disease transmission to others. Treating recent sexual contacts (those having sexual contact with the patient within 60 days prior to symptom onset) also prevents reinfection of the index patient. […] Antibiotic therapy for urethritis should cover both gonococcal urethritis (GU) and nongonococcal urethritis (NGU). The choice of antibiotics should be based on effectiveness, adverse effects, cost, and compliance. In most situations, optimal treatment is with single-dose therapy administered in the emergency department or the physician’s office. […] Currently, the CDC recommends a single dose of ceftriaxone 500 mg IM (1 g IM in patients weighing 150 kg) for the treatment of GU. If ceftriaxone is unavailable, administer cefixime 800 mg orally in a single dose. If the patient has a cephalosporin allergy or a type 1 hypersensitivity reaction to penicillins, treat with gentamicin 240 mg IM plus azithromycin, 2 g orally. If chlamydial infection has not been excluded, treatment should also include doxycycline, 100 mg orally twice a day for 7 days.
- #7 Urethritis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK537282/
The recommended treatment for gonococcal urethritis is a single dose of ceftriaxone 500 mg administered intramuscularly (IM) or intravenously (IV) for patients with a body weight of less than 150 kg. For patients with a body weight of 150 kg or more, 1 g of ceftriaxone IM/IV is recommended. If C trachomatis infection has not been definitively ruled out, additional treatment with doxycycline 100 mg taken orally twice daily for 7 days should be administered. […] Nongonococcal urethritis typically warrants empiric therapy with doxycycline 100 mg twice daily for 7 days, unless otherwise indicated. For C trachomatis, the preferred treatment is doxycycline 100 mg orally twice daily for 7 days. An alternative regimen includes azithromycin 500 mg taken orally as a single dose, followed by 250 mg orally daily for 4 days.
- #8 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
Symptoms of urethritis typically resolve spontaneously over time, regardless of treatment. Administer antibiotics to prevent morbidity and to reduce disease transmission to others. Treating recent sexual contacts (those having sexual contact with the patient within 60 days prior to symptom onset) also prevents reinfection of the index patient. […] Antibiotic therapy for urethritis should cover both gonococcal urethritis (GU) and nongonococcal urethritis (NGU). The choice of antibiotics should be based on effectiveness, adverse effects, cost, and compliance. In most situations, optimal treatment is with single-dose therapy administered in the emergency department or the physician’s office. […] Currently, the CDC recommends a single dose of ceftriaxone 500 mg IM (1 g IM in patients weighing 150 kg) for the treatment of GU. If ceftriaxone is unavailable, administer cefixime 800 mg orally in a single dose. If the patient has a cephalosporin allergy or a type 1 hypersensitivity reaction to penicillins, treat with gentamicin 240 mg IM plus azithromycin, 2 g orally. If chlamydial infection has not been excluded, treatment should also include doxycycline, 100 mg orally twice a day for 7 days.
- #9 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
For treatment of NGU, the CDC currently recommends doxycycline, 100 mg orally twice a day for 7 days. Alternative regimens include a single dose of 1 g azithromycin orally, or 500 mg orally followed by 250 mg orally daily for 4 days. […] Patients with persistent symptoms should be reevaluated. In those with persistent or recurrent NGU, the most common organism is Mycoplasma genitalium, especially following treatment with doxycycline. Antimicrobial resistance is noted to be high for M genitalium. […] The CDC recommends a two-stage approach for treatment for M genitalium. If M genitalium resistance testing is available it should be performed, and the results should be used to guide therapy. Treatment of macrolide-sensitive M genitalium infection is with doxycycline 100 mg orally 2 times/day for 7 days followed by azithromycin, 1 g orally initial dose then 500 mg orally daily for 3 additional days (2.5 g total).
- #10 Urethritis and Cervicitis – STI Treatment Guidelineshttps://www.cdc.gov/std/treatment-guidelines/urethritis-and-cervicitis.htm
Meningococcal urethritis is treated with the same antimicrobial regimens as gonococcal urethritis. […] Treatment of sex partners of patients with meningococcal urethritis with the same antimicrobial regimens as for exposure to gonococcal infection can be considered. […] NGU is a nonspecific diagnosis that can have various infectious etiologies. […] Doxycycline is highly effective for chlamydial urethral infections and is also effective for chlamydial infections of the rectum; it also has some activity against M. genitalium. […] Recommended Regimen for Nongonococcal Urethritis: Doxycycline 100 mg orally 2 times/day for 7 days. […] To minimize transmission and reinfections, men treated for NGU should be instructed to abstain from sexual intercourse until they and their partners have been treated.
- #11 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
For treatment of NGU, the CDC currently recommends doxycycline, 100 mg orally twice a day for 7 days. Alternative regimens include a single dose of 1 g azithromycin orally, or 500 mg orally followed by 250 mg orally daily for 4 days. […] Patients with persistent symptoms should be reevaluated. In those with persistent or recurrent NGU, the most common organism is Mycoplasma genitalium, especially following treatment with doxycycline. Antimicrobial resistance is noted to be high for M genitalium. […] The CDC recommends a two-stage approach for treatment for M genitalium. If M genitalium resistance testing is available it should be performed, and the results should be used to guide therapy. Treatment of macrolide-sensitive M genitalium infection is with doxycycline 100 mg orally 2 times/day for 7 days followed by azithromycin, 1 g orally initial dose then 500 mg orally daily for 3 additional days (2.5 g total).
- #12 Urethritis and Cervicitis – STI Treatment Guidelineshttps://www.cdc.gov/std/treatment-guidelines/urethritis-and-cervicitis.htm
Meningococcal urethritis is treated with the same antimicrobial regimens as gonococcal urethritis. […] Treatment of sex partners of patients with meningococcal urethritis with the same antimicrobial regimens as for exposure to gonococcal infection can be considered. […] NGU is a nonspecific diagnosis that can have various infectious etiologies. […] Doxycycline is highly effective for chlamydial urethral infections and is also effective for chlamydial infections of the rectum; it also has some activity against M. genitalium. […] Recommended Regimen for Nongonococcal Urethritis: Doxycycline 100 mg orally 2 times/day for 7 days. […] To minimize transmission and reinfections, men treated for NGU should be instructed to abstain from sexual intercourse until they and their partners have been treated.
- #13 Urethritis and Cervicitis – STI Treatment Guidelineshttps://www.cdc.gov/std/treatment-guidelines/urethritis-and-cervicitis.htm
Urethritis, as characterized by urethral inflammation, can result from either infectious or noninfectious conditions. […] If POC diagnostic tools (e.g., Gram, methylene blue [MB], or gentian violet [GV] stain microscopy) are unavailable, drug regimens effective against both gonorrhea and chlamydia should be administered. […] Both chlamydia and gonorrhea are reportable to health departments. […] NAATs are preferred for detecting C. trachomatis and N. gonorrhoeae, and urine is the preferred specimen for males. […] M. genitalium is associated with symptoms of urethritis and urethral inflammation and accounts for 15%25% of NGU cases in the United States. […] T. vaginalis can cause urethritis among heterosexual men; however, the prevalence varies substantially by U.S. geographic region, age, and sexual behavior and within specific populations.
- #14 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
For treatment of NGU, the CDC currently recommends doxycycline, 100 mg orally twice a day for 7 days. Alternative regimens include a single dose of 1 g azithromycin orally, or 500 mg orally followed by 250 mg orally daily for 4 days. […] Patients with persistent symptoms should be reevaluated. In those with persistent or recurrent NGU, the most common organism is Mycoplasma genitalium, especially following treatment with doxycycline. Antimicrobial resistance is noted to be high for M genitalium. […] The CDC recommends a two-stage approach for treatment for M genitalium. If M genitalium resistance testing is available it should be performed, and the results should be used to guide therapy. Treatment of macrolide-sensitive M genitalium infection is with doxycycline 100 mg orally 2 times/day for 7 days followed by azithromycin, 1 g orally initial dose then 500 mg orally daily for 3 additional days (2.5 g total).
- #15 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
For treatment of NGU, the CDC currently recommends doxycycline, 100 mg orally twice a day for 7 days. Alternative regimens include a single dose of 1 g azithromycin orally, or 500 mg orally followed by 250 mg orally daily for 4 days. […] Patients with persistent symptoms should be reevaluated. In those with persistent or recurrent NGU, the most common organism is Mycoplasma genitalium, especially following treatment with doxycycline. Antimicrobial resistance is noted to be high for M genitalium. […] The CDC recommends a two-stage approach for treatment for M genitalium. If M genitalium resistance testing is available it should be performed, and the results should be used to guide therapy. Treatment of macrolide-sensitive M genitalium infection is with doxycycline 100 mg orally 2 times/day for 7 days followed by azithromycin, 1 g orally initial dose then 500 mg orally daily for 3 additional days (2.5 g total).
- #16 Urethritis and Cervicitis – STI Treatment Guidelineshttps://www.cdc.gov/std/treatment-guidelines/urethritis-and-cervicitis.htm
If symptoms persist or recur after therapy completion, men should be instructed to return for reevaluation and should be tested for M. genitalium and T. vaginalis. […] The initial step in recurrent urethritis is assessing compliance with treatment or potential reexposure to an untreated sex partner. […] If T. vaginalis is unlikely, men with recurrent NGU should be tested for M. genitalium by using an FDA-cleared NAAT. […] Treatment for M. genitalium includes a two-stage approach, ideally using resistance-guided therapy. […] If M. genitalium resistance testing is not available, doxycycline 100 mg orally 2 times/day for 7 days followed by moxifloxacin 400 mg orally once daily for 7 days should be used.
- #17 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
For treatment of NGU, the CDC currently recommends doxycycline, 100 mg orally twice a day for 7 days. Alternative regimens include a single dose of 1 g azithromycin orally, or 500 mg orally followed by 250 mg orally daily for 4 days. […] Patients with persistent symptoms should be reevaluated. In those with persistent or recurrent NGU, the most common organism is Mycoplasma genitalium, especially following treatment with doxycycline. Antimicrobial resistance is noted to be high for M genitalium. […] The CDC recommends a two-stage approach for treatment for M genitalium. If M genitalium resistance testing is available it should be performed, and the results should be used to guide therapy. Treatment of macrolide-sensitive M genitalium infection is with doxycycline 100 mg orally 2 times/day for 7 days followed by azithromycin, 1 g orally initial dose then 500 mg orally daily for 3 additional days (2.5 g total).
- #18 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
If M genitalium resistance testing is not available, the recommended treatment is doxycycline 100 mg orally 2 times/day for 7 days followed by moxifloxacin 400 mg orally once daily for 7 days. […] Trichomonas vaginalis infection should be considered in heterosexual patients with persistent symptoms. In regions where T vaginalis is prevalent, patients with urethritis should be treated empirically with metronidazole 2 g orally in a single dose or tinidazole 2 g orally in a single dose.
- #19 Urethritis and Cervicitis – STI Treatment Guidelineshttps://www.cdc.gov/std/treatment-guidelines/urethritis-and-cervicitis.htm
If symptoms persist or recur after therapy completion, men should be instructed to return for reevaluation and should be tested for M. genitalium and T. vaginalis. […] The initial step in recurrent urethritis is assessing compliance with treatment or potential reexposure to an untreated sex partner. […] If T. vaginalis is unlikely, men with recurrent NGU should be tested for M. genitalium by using an FDA-cleared NAAT. […] Treatment for M. genitalium includes a two-stage approach, ideally using resistance-guided therapy. […] If M. genitalium resistance testing is not available, doxycycline 100 mg orally 2 times/day for 7 days followed by moxifloxacin 400 mg orally once daily for 7 days should be used.
- #20 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
If M genitalium resistance testing is not available, the recommended treatment is doxycycline 100 mg orally 2 times/day for 7 days followed by moxifloxacin 400 mg orally once daily for 7 days. […] Trichomonas vaginalis infection should be considered in heterosexual patients with persistent symptoms. In regions where T vaginalis is prevalent, patients with urethritis should be treated empirically with metronidazole 2 g orally in a single dose or tinidazole 2 g orally in a single dose.
- #21 Urethritis: Causes, Symptoms, and Treatmenthttps://www.webmd.com/a-to-z-guides/urethritis-symptoms-causes-treatments
Antibiotics can successfully cure urethritis caused by bacteria. Many different antibiotics can treat urethritis. Some of the most commonly prescribed include: […] Urethritis due to trichomonas infection (called trichomoniasis) is usually treated with an antibiotic called metronidazole (Flagyl). Tinidazole (Tindamax) is another antibiotic that can treat trichomoniasis. […] Urethritis due to herpes simplex virus can be treated with: Acyclovir (Zovirax), Famciclovir (Famvir), Valacyclovir (Valtrex). […] Often, the exact organism causing urethritis cannot be identified. In these situations, a doctor may prescribe one or more antibiotics that are likely to cure infection that may be present.
- #22 Urethritis: Causes, Symptoms, and Treatmenthttps://www.webmd.com/a-to-z-guides/urethritis-symptoms-causes-treatments
Antibiotics can successfully cure urethritis caused by bacteria. Many different antibiotics can treat urethritis. Some of the most commonly prescribed include: […] Urethritis due to trichomonas infection (called trichomoniasis) is usually treated with an antibiotic called metronidazole (Flagyl). Tinidazole (Tindamax) is another antibiotic that can treat trichomoniasis. […] Urethritis due to herpes simplex virus can be treated with: Acyclovir (Zovirax), Famciclovir (Famvir), Valacyclovir (Valtrex). […] Often, the exact organism causing urethritis cannot be identified. In these situations, a doctor may prescribe one or more antibiotics that are likely to cure infection that may be present.
- #23 Urethritis: Causes, Symptoms, and Treatmenthttps://www.webmd.com/a-to-z-guides/urethritis-symptoms-causes-treatments
Antibiotics can successfully cure urethritis caused by bacteria. Many different antibiotics can treat urethritis. Some of the most commonly prescribed include: […] Urethritis due to trichomonas infection (called trichomoniasis) is usually treated with an antibiotic called metronidazole (Flagyl). Tinidazole (Tindamax) is another antibiotic that can treat trichomoniasis. […] Urethritis due to herpes simplex virus can be treated with: Acyclovir (Zovirax), Famciclovir (Famvir), Valacyclovir (Valtrex). […] Often, the exact organism causing urethritis cannot be identified. In these situations, a doctor may prescribe one or more antibiotics that are likely to cure infection that may be present.
- #24 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
For treatment of NGU, the CDC currently recommends doxycycline, 100 mg orally twice a day for 7 days. Alternative regimens include a single dose of 1 g azithromycin orally, or 500 mg orally followed by 250 mg orally daily for 4 days. […] Patients with persistent symptoms should be reevaluated. In those with persistent or recurrent NGU, the most common organism is Mycoplasma genitalium, especially following treatment with doxycycline. Antimicrobial resistance is noted to be high for M genitalium. […] The CDC recommends a two-stage approach for treatment for M genitalium. If M genitalium resistance testing is available it should be performed, and the results should be used to guide therapy. Treatment of macrolide-sensitive M genitalium infection is with doxycycline 100 mg orally 2 times/day for 7 days followed by azithromycin, 1 g orally initial dose then 500 mg orally daily for 3 additional days (2.5 g total).
- #25 Urethritis and Cervicitis – STI Treatment Guidelineshttps://www.cdc.gov/std/treatment-guidelines/urethritis-and-cervicitis.htm
If symptoms persist or recur after therapy completion, men should be instructed to return for reevaluation and should be tested for M. genitalium and T. vaginalis. […] The initial step in recurrent urethritis is assessing compliance with treatment or potential reexposure to an untreated sex partner. […] If T. vaginalis is unlikely, men with recurrent NGU should be tested for M. genitalium by using an FDA-cleared NAAT. […] Treatment for M. genitalium includes a two-stage approach, ideally using resistance-guided therapy. […] If M. genitalium resistance testing is not available, doxycycline 100 mg orally 2 times/day for 7 days followed by moxifloxacin 400 mg orally once daily for 7 days should be used.
- #26 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
For treatment of NGU, the CDC currently recommends doxycycline, 100 mg orally twice a day for 7 days. Alternative regimens include a single dose of 1 g azithromycin orally, or 500 mg orally followed by 250 mg orally daily for 4 days. […] Patients with persistent symptoms should be reevaluated. In those with persistent or recurrent NGU, the most common organism is Mycoplasma genitalium, especially following treatment with doxycycline. Antimicrobial resistance is noted to be high for M genitalium. […] The CDC recommends a two-stage approach for treatment for M genitalium. If M genitalium resistance testing is available it should be performed, and the results should be used to guide therapy. Treatment of macrolide-sensitive M genitalium infection is with doxycycline 100 mg orally 2 times/day for 7 days followed by azithromycin, 1 g orally initial dose then 500 mg orally daily for 3 additional days (2.5 g total).
- #27 Urethritis and Cervicitis – STI Treatment Guidelineshttps://www.cdc.gov/std/treatment-guidelines/urethritis-and-cervicitis.htm
If symptoms persist or recur after therapy completion, men should be instructed to return for reevaluation and should be tested for M. genitalium and T. vaginalis. […] The initial step in recurrent urethritis is assessing compliance with treatment or potential reexposure to an untreated sex partner. […] If T. vaginalis is unlikely, men with recurrent NGU should be tested for M. genitalium by using an FDA-cleared NAAT. […] Treatment for M. genitalium includes a two-stage approach, ideally using resistance-guided therapy. […] If M. genitalium resistance testing is not available, doxycycline 100 mg orally 2 times/day for 7 days followed by moxifloxacin 400 mg orally once daily for 7 days should be used.
- #28 Urethritis: MedlinePlus Medical EncyclopediaLockhttps://medlineplus.gov/ency/article/000439.htm
The goals of treatment are to: […] If you have a bacterial infection, you will be given antibiotics. […] You may take both pain relievers for general body pain and products for localized urinary tract pain, plus antibiotics. […] People with urethritis who are being treated should avoid sex, or use condoms during sex. Your sexual partner must also be treated if the condition is caused by an infection. […] Urethritis caused by trauma or chemical irritants is treated by avoiding the source of injury or irritation. […] Urethritis that does not clear up after antibiotic treatment and lasts for at least 6 weeks is called chronic urethritis. Different antibiotics may be used to treat this problem.
- #29 Urethritis: Causes, Symptoms, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/22858-urethritis
Antibiotics are the standard treatment. […] Antibiotics are the main treatment for urethritis, either alone or in combination. Some of the antibiotics used to treat urethritis include: Azithromycin, Doxycycline, Ofloxacin, Levofloxacin, Ceftriaxone, Cefixime. […] Your provider may start you on antibiotics even before getting results back if they believe you have an infection. […] If you have urethritis from friction or from using irritating chemicals like soap or spermicide, your provider will suggest that you stop wearing tight clothing, stop using the irritant and cut back on the time you spend doing the activity that causes friction. […] Make sure to take all of your antibiotics as instructed by your healthcare provider. Usually, you’ll need to take the medications for a week to 10 days. You’ll probably begin to feel better after a few days, but it’s important to make sure that you take the entire prescription. […] If you have urethritis and you’re treated with the correct medication, you should be cured entirely. It’s important to note that your sexual partners must also take the medication. If only one of you is treated, you can continue to pass the infection back and forth. […] Urethritis can be cured.
- #30 Urethritis Treatment – Urology of Greater Atlantahttps://ugatl.com/services/std/urethritis/
Treatment will prevent its spread and prevent further complications from developing. […] The primary treatment for urethritis, whether used alone or in combination, involves the administration of antibiotics. Several antibiotics commonly used to treat urethritis caused by bacteria include the following: Azithromycin, Doxycycline, Ofloxacin, Levofloxacin, Ceftriaxone, Cefixime. […] In some cases, your healthcare provider may initiate antibiotic treatment before receiving the test results if a bacterial infection is suspected. […] Urethritis that does not clear up after six weeks of antibiotic treatment is called chronic urethritis. Different antibiotics may be used to treat this problem. […] If urethritis is caused by friction or exposure to irritating substances like soap or spermicide, your provider may advise the following measures: Stop wearing tight-fitting clothing, Avoiding the irritant substance, Limiting the duration of activities that induce friction.
- #31 Urethritis: Causes, Symptoms, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/22858-urethritis
Antibiotics are the standard treatment. […] Antibiotics are the main treatment for urethritis, either alone or in combination. Some of the antibiotics used to treat urethritis include: Azithromycin, Doxycycline, Ofloxacin, Levofloxacin, Ceftriaxone, Cefixime. […] Your provider may start you on antibiotics even before getting results back if they believe you have an infection. […] If you have urethritis from friction or from using irritating chemicals like soap or spermicide, your provider will suggest that you stop wearing tight clothing, stop using the irritant and cut back on the time you spend doing the activity that causes friction. […] Make sure to take all of your antibiotics as instructed by your healthcare provider. Usually, you’ll need to take the medications for a week to 10 days. You’ll probably begin to feel better after a few days, but it’s important to make sure that you take the entire prescription. […] If you have urethritis and you’re treated with the correct medication, you should be cured entirely. It’s important to note that your sexual partners must also take the medication. If only one of you is treated, you can continue to pass the infection back and forth. […] Urethritis can be cured.
- #32 Urethritis – Harvard Healthhttps://www.health.harvard.edu/diseases-and-conditions/urethritis-a-to-z
Infectious urethritis can be treated with a variety of antibiotics. […] Because many people have gonorrhea and chlamydia at the same time, health experts recommend that all people treated for gonorrhea receive treatment for chlamydia as well. […] No specific treatment is needed for urethritis caused by injury or chemical irritation. Your doctor may prescribe phenazopyridine (Pyridium) to ease any burning or pain with urination. […] Urethritis associated with reactive arthritis is treated with non-steroidal anti-inflammatory drugs (NSAIDs), such as naproxen.
- #33 Urethritis: Symptoms, causes, and treatmenthttps://www.medicalnewstoday.com/articles/264903
Medications aim to treat the cause of urethritis and prevent the spread of infection. […] Treatment depends on the underlying cause. If a person has a bacterial infection, a doctor may prescribe an antibiotic, such as: doxycycline, azithromycin, metronidazole. […] Doctors may also recommend: nonsteroidal anti-inflammatory drugs (NSAIDs), such as naproxen, to relieve pain; phenazopyridine, which can reduce the urge to urinate and the frequency of urination. […] The CDC recommends treatment that can be given in a single dose to encourage adherence. They also recommend giving medication on-site in the clinic and observing the first dose. […] Treatment with antibiotics is usually effective in clearing up urethritis. If symptoms do not improve, a person should talk with a doctor as another condition may be playing a role.
- #34 Urethritis: Symptoms, causes, and treatmenthttps://www.medicalnewstoday.com/articles/264903
Medications aim to treat the cause of urethritis and prevent the spread of infection. […] Treatment depends on the underlying cause. If a person has a bacterial infection, a doctor may prescribe an antibiotic, such as: doxycycline, azithromycin, metronidazole. […] Doctors may also recommend: nonsteroidal anti-inflammatory drugs (NSAIDs), such as naproxen, to relieve pain; phenazopyridine, which can reduce the urge to urinate and the frequency of urination. […] The CDC recommends treatment that can be given in a single dose to encourage adherence. They also recommend giving medication on-site in the clinic and observing the first dose. […] Treatment with antibiotics is usually effective in clearing up urethritis. If symptoms do not improve, a person should talk with a doctor as another condition may be playing a role.
- #35 Urethritis: Care Instructions | Kaiser Permanentehttps://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.urethritis-care-instructions.ut2089
Urethritis is usually treated with antibiotics. Most cases clear up with treatment. Proper treatment is very important. If you don’t treat it, the infection can lead to lasting damage of the urethra. Other parts of the urinary system can also be damaged. […] If your doctor prescribed antibiotics, take them as directed. Do not stop taking them just because you feel better. You need to take the full course of antibiotics. […] Your doctor may have you take phenazopyridine (Pyridium). This is a pain medicine for the urinary tract. It can turn your urine a deep red-orange. This is normal. Call your doctor if you think you are having a problem with your medicine. […] Do not have sex until you are done with treatment. If you do have sex, be sure to use a condom. Your sex partner or partners should be tested too if your urethritis was caused by an STI.
- #36 Urethritis: Causes, Symptoms, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/22858-urethritis
Antibiotics are the standard treatment. […] Antibiotics are the main treatment for urethritis, either alone or in combination. Some of the antibiotics used to treat urethritis include: Azithromycin, Doxycycline, Ofloxacin, Levofloxacin, Ceftriaxone, Cefixime. […] Your provider may start you on antibiotics even before getting results back if they believe you have an infection. […] If you have urethritis from friction or from using irritating chemicals like soap or spermicide, your provider will suggest that you stop wearing tight clothing, stop using the irritant and cut back on the time you spend doing the activity that causes friction. […] Make sure to take all of your antibiotics as instructed by your healthcare provider. Usually, you’ll need to take the medications for a week to 10 days. You’ll probably begin to feel better after a few days, but it’s important to make sure that you take the entire prescription. […] If you have urethritis and you’re treated with the correct medication, you should be cured entirely. It’s important to note that your sexual partners must also take the medication. If only one of you is treated, you can continue to pass the infection back and forth. […] Urethritis can be cured.
- #37 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
Symptoms of urethritis typically resolve spontaneously over time, regardless of treatment. Administer antibiotics to prevent morbidity and to reduce disease transmission to others. Treating recent sexual contacts (those having sexual contact with the patient within 60 days prior to symptom onset) also prevents reinfection of the index patient. […] Antibiotic therapy for urethritis should cover both gonococcal urethritis (GU) and nongonococcal urethritis (NGU). The choice of antibiotics should be based on effectiveness, adverse effects, cost, and compliance. In most situations, optimal treatment is with single-dose therapy administered in the emergency department or the physician’s office. […] Currently, the CDC recommends a single dose of ceftriaxone 500 mg IM (1 g IM in patients weighing 150 kg) for the treatment of GU. If ceftriaxone is unavailable, administer cefixime 800 mg orally in a single dose. If the patient has a cephalosporin allergy or a type 1 hypersensitivity reaction to penicillins, treat with gentamicin 240 mg IM plus azithromycin, 2 g orally. If chlamydial infection has not been excluded, treatment should also include doxycycline, 100 mg orally twice a day for 7 days.
- #38 Urethritis: Causes, Symptoms, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/22858-urethritis
Antibiotics are the standard treatment. […] Antibiotics are the main treatment for urethritis, either alone or in combination. Some of the antibiotics used to treat urethritis include: Azithromycin, Doxycycline, Ofloxacin, Levofloxacin, Ceftriaxone, Cefixime. […] Your provider may start you on antibiotics even before getting results back if they believe you have an infection. […] If you have urethritis from friction or from using irritating chemicals like soap or spermicide, your provider will suggest that you stop wearing tight clothing, stop using the irritant and cut back on the time you spend doing the activity that causes friction. […] Make sure to take all of your antibiotics as instructed by your healthcare provider. Usually, you’ll need to take the medications for a week to 10 days. You’ll probably begin to feel better after a few days, but it’s important to make sure that you take the entire prescription. […] If you have urethritis and you’re treated with the correct medication, you should be cured entirely. It’s important to note that your sexual partners must also take the medication. If only one of you is treated, you can continue to pass the infection back and forth. […] Urethritis can be cured.
- #39 Nongonococcal Urethritis (NGU): Causes, Symptoms & Treatmenthttps://my.clevelandclinic.org/health/diseases/4426-nongonococcal-urethritis
Nongonococcal urethritis (NGU) is usually a sexually transmitted infection, although urethral trauma can also cause it. Healthcare providers treat NGU with antibiotics. Make sure to take all of your medicine. […] Healthcare providers will prescribe antibiotics to destroy the germs that cause nongonococcal urethritis. A provider may prescribe: Doxycycline. Youll take doxycycline twice a day for a week. […] If youre allergic to these medications, or they dont get rid of the infection, your provider may prescribe erythromycin or ofloxacin. […] You and your partner(s) should receive treatment. If only one partner receives treatment, you may continue to pass NGU back and forth to each other. […] It may take a week or two for your symptoms to go away after starting antibiotics. […] Schedule an appointment with a healthcare provider if you notice that you or your partner have any symptoms of NGU. Its also a good idea to get annual (yearly) or more frequent STI testing if youre sexually active with multiple partners.
- #40 Urethritis: Rapid Evidence Review | AAFPhttps://www.aafp.org/pubs/afp/issues/2021/0501/p553.html
Expedited partner therapy (prescribing treatment for sex partners of patients with newly diagnosed chlamydia or gonorrhea without examining the partner) is legal in most states. […] NAAT can have false-positive results when performed less than three weeks after a patient has completed treatment for gonorrhea or chlamydia; therefore, a test of cure is not advised during this time.
- #41 Urethritis and Cervicitis – STI Treatment Guidelineshttps://www.cdc.gov/std/treatment-guidelines/urethritis-and-cervicitis.htm
Meningococcal urethritis is treated with the same antimicrobial regimens as gonococcal urethritis. […] Treatment of sex partners of patients with meningococcal urethritis with the same antimicrobial regimens as for exposure to gonococcal infection can be considered. […] NGU is a nonspecific diagnosis that can have various infectious etiologies. […] Doxycycline is highly effective for chlamydial urethral infections and is also effective for chlamydial infections of the rectum; it also has some activity against M. genitalium. […] Recommended Regimen for Nongonococcal Urethritis: Doxycycline 100 mg orally 2 times/day for 7 days. […] To minimize transmission and reinfections, men treated for NGU should be instructed to abstain from sexual intercourse until they and their partners have been treated.
- #42 Urethritishttps://www.nhs.uk/conditions/urethritis/
Urethritis is usually treated with antibiotics. It may take a week or two for your symptoms to disappear completely. […] Any current sexual partners may also need treatment. […] Avoid having sex (including oral sex) until you and any sexual partners have finished treatment and the symptoms have gone. […] You may be asked to come back for another appointment in 1 to 2 weeks to check the treatment has worked.
- #43 Urethritishttps://www.nhs.uk/conditions/urethritis/
Urethritis is usually treated with antibiotics. It may take a week or two for your symptoms to disappear completely. […] Any current sexual partners may also need treatment. […] Avoid having sex (including oral sex) until you and any sexual partners have finished treatment and the symptoms have gone. […] You may be asked to come back for another appointment in 1 to 2 weeks to check the treatment has worked.
- #44 Urethritis: Care Instructions | Kaiser Permanentehttps://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.urethritis-care-instructions.ut2089
Urethritis is usually treated with antibiotics. Most cases clear up with treatment. Proper treatment is very important. If you don’t treat it, the infection can lead to lasting damage of the urethra. Other parts of the urinary system can also be damaged. […] If your doctor prescribed antibiotics, take them as directed. Do not stop taking them just because you feel better. You need to take the full course of antibiotics. […] Your doctor may have you take phenazopyridine (Pyridium). This is a pain medicine for the urinary tract. It can turn your urine a deep red-orange. This is normal. Call your doctor if you think you are having a problem with your medicine. […] Do not have sex until you are done with treatment. If you do have sex, be sure to use a condom. Your sex partner or partners should be tested too if your urethritis was caused by an STI.
- #45 Urethritishttps://www.nhs.uk/conditions/urethritis/
Urethritis is usually treated with antibiotics. It may take a week or two for your symptoms to disappear completely. […] Any current sexual partners may also need treatment. […] Avoid having sex (including oral sex) until you and any sexual partners have finished treatment and the symptoms have gone. […] You may be asked to come back for another appointment in 1 to 2 weeks to check the treatment has worked.
- #46 Urethritis: Causes, Symptoms, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/22858-urethritis
Antibiotics are the standard treatment. […] Antibiotics are the main treatment for urethritis, either alone or in combination. Some of the antibiotics used to treat urethritis include: Azithromycin, Doxycycline, Ofloxacin, Levofloxacin, Ceftriaxone, Cefixime. […] Your provider may start you on antibiotics even before getting results back if they believe you have an infection. […] If you have urethritis from friction or from using irritating chemicals like soap or spermicide, your provider will suggest that you stop wearing tight clothing, stop using the irritant and cut back on the time you spend doing the activity that causes friction. […] Make sure to take all of your antibiotics as instructed by your healthcare provider. Usually, you’ll need to take the medications for a week to 10 days. You’ll probably begin to feel better after a few days, but it’s important to make sure that you take the entire prescription. […] If you have urethritis and you’re treated with the correct medication, you should be cured entirely. It’s important to note that your sexual partners must also take the medication. If only one of you is treated, you can continue to pass the infection back and forth. […] Urethritis can be cured.
- #47 Nongonococcal Urethritis (NGU): Causes, Symptoms & Treatmenthttps://my.clevelandclinic.org/health/diseases/4426-nongonococcal-urethritis
Nongonococcal urethritis (NGU) is usually a sexually transmitted infection, although urethral trauma can also cause it. Healthcare providers treat NGU with antibiotics. Make sure to take all of your medicine. […] Healthcare providers will prescribe antibiotics to destroy the germs that cause nongonococcal urethritis. A provider may prescribe: Doxycycline. Youll take doxycycline twice a day for a week. […] If youre allergic to these medications, or they dont get rid of the infection, your provider may prescribe erythromycin or ofloxacin. […] You and your partner(s) should receive treatment. If only one partner receives treatment, you may continue to pass NGU back and forth to each other. […] It may take a week or two for your symptoms to go away after starting antibiotics. […] Schedule an appointment with a healthcare provider if you notice that you or your partner have any symptoms of NGU. Its also a good idea to get annual (yearly) or more frequent STI testing if youre sexually active with multiple partners.
- #48 Urethritis and Cervicitis – STI Treatment Guidelineshttps://www.cdc.gov/std/treatment-guidelines/urethritis-and-cervicitis.htm
If symptoms persist or recur after therapy completion, men should be instructed to return for reevaluation and should be tested for M. genitalium and T. vaginalis. […] The initial step in recurrent urethritis is assessing compliance with treatment or potential reexposure to an untreated sex partner. […] If T. vaginalis is unlikely, men with recurrent NGU should be tested for M. genitalium by using an FDA-cleared NAAT. […] Treatment for M. genitalium includes a two-stage approach, ideally using resistance-guided therapy. […] If M. genitalium resistance testing is not available, doxycycline 100 mg orally 2 times/day for 7 days followed by moxifloxacin 400 mg orally once daily for 7 days should be used.
- #49 Urethritis: Rapid Evidence Review | AAFPhttps://www.aafp.org/pubs/afp/issues/2021/0501/p553.html
Expedited partner therapy (prescribing treatment for sex partners of patients with newly diagnosed chlamydia or gonorrhea without examining the partner) is legal in most states. […] NAAT can have false-positive results when performed less than three weeks after a patient has completed treatment for gonorrhea or chlamydia; therefore, a test of cure is not advised during this time.
- #50 Urethritis: Causes, Symptoms, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/22858-urethritis
Antibiotics are the standard treatment. […] Antibiotics are the main treatment for urethritis, either alone or in combination. Some of the antibiotics used to treat urethritis include: Azithromycin, Doxycycline, Ofloxacin, Levofloxacin, Ceftriaxone, Cefixime. […] Your provider may start you on antibiotics even before getting results back if they believe you have an infection. […] If you have urethritis from friction or from using irritating chemicals like soap or spermicide, your provider will suggest that you stop wearing tight clothing, stop using the irritant and cut back on the time you spend doing the activity that causes friction. […] Make sure to take all of your antibiotics as instructed by your healthcare provider. Usually, you’ll need to take the medications for a week to 10 days. You’ll probably begin to feel better after a few days, but it’s important to make sure that you take the entire prescription. […] If you have urethritis and you’re treated with the correct medication, you should be cured entirely. It’s important to note that your sexual partners must also take the medication. If only one of you is treated, you can continue to pass the infection back and forth. […] Urethritis can be cured.
- #51 Urethritis: Practice Essentials, Pathophysiology, Etiologyhttps://emedicine.medscape.com/article/2012150-overview
Symptoms of urethritis spontaneously resolve over time, regardless of treatment. […] Administer antibiotics that cover both GU and NGU. Regardless of symptoms, administer antibiotics to the following individuals: […] Antibiotics used in the treatment of urethritis include the following: Azithromycin, Ceftriaxone, Cefixime, Gentamicin, Doxycycline, Erythromycin, Levofloxacin, Ofloxacin, Moxifloxacin.
- #52 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
Symptoms of urethritis typically resolve spontaneously over time, regardless of treatment. Administer antibiotics to prevent morbidity and to reduce disease transmission to others. Treating recent sexual contacts (those having sexual contact with the patient within 60 days prior to symptom onset) also prevents reinfection of the index patient. […] Antibiotic therapy for urethritis should cover both gonococcal urethritis (GU) and nongonococcal urethritis (NGU). The choice of antibiotics should be based on effectiveness, adverse effects, cost, and compliance. In most situations, optimal treatment is with single-dose therapy administered in the emergency department or the physician’s office. […] Currently, the CDC recommends a single dose of ceftriaxone 500 mg IM (1 g IM in patients weighing 150 kg) for the treatment of GU. If ceftriaxone is unavailable, administer cefixime 800 mg orally in a single dose. If the patient has a cephalosporin allergy or a type 1 hypersensitivity reaction to penicillins, treat with gentamicin 240 mg IM plus azithromycin, 2 g orally. If chlamydial infection has not been excluded, treatment should also include doxycycline, 100 mg orally twice a day for 7 days.
- #53 Urethritis: Practice Essentials, Pathophysiology, Etiologyhttps://emedicine.medscape.com/article/2012150-overview
Symptoms of urethritis spontaneously resolve over time, regardless of treatment. […] Administer antibiotics that cover both GU and NGU. Regardless of symptoms, administer antibiotics to the following individuals: […] Antibiotics used in the treatment of urethritis include the following: Azithromycin, Ceftriaxone, Cefixime, Gentamicin, Doxycycline, Erythromycin, Levofloxacin, Ofloxacin, Moxifloxacin.
- #54 Urethritis: Causes, Symptoms, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/22858-urethritis
Antibiotics are the standard treatment. […] Antibiotics are the main treatment for urethritis, either alone or in combination. Some of the antibiotics used to treat urethritis include: Azithromycin, Doxycycline, Ofloxacin, Levofloxacin, Ceftriaxone, Cefixime. […] Your provider may start you on antibiotics even before getting results back if they believe you have an infection. […] If you have urethritis from friction or from using irritating chemicals like soap or spermicide, your provider will suggest that you stop wearing tight clothing, stop using the irritant and cut back on the time you spend doing the activity that causes friction. […] Make sure to take all of your antibiotics as instructed by your healthcare provider. Usually, you’ll need to take the medications for a week to 10 days. You’ll probably begin to feel better after a few days, but it’s important to make sure that you take the entire prescription. […] If you have urethritis and you’re treated with the correct medication, you should be cured entirely. It’s important to note that your sexual partners must also take the medication. If only one of you is treated, you can continue to pass the infection back and forth. […] Urethritis can be cured.
- #55 Urethritishttps://www.nhs.uk/conditions/urethritis/
Urethritis is usually treated with antibiotics. It may take a week or two for your symptoms to disappear completely. […] Any current sexual partners may also need treatment. […] Avoid having sex (including oral sex) until you and any sexual partners have finished treatment and the symptoms have gone. […] You may be asked to come back for another appointment in 1 to 2 weeks to check the treatment has worked.
- #56 Nongonococcal Urethritis (NGU): Causes, Symptoms & Treatmenthttps://my.clevelandclinic.org/health/diseases/4426-nongonococcal-urethritis
Nongonococcal urethritis (NGU) is usually a sexually transmitted infection, although urethral trauma can also cause it. Healthcare providers treat NGU with antibiotics. Make sure to take all of your medicine. […] Healthcare providers will prescribe antibiotics to destroy the germs that cause nongonococcal urethritis. A provider may prescribe: Doxycycline. Youll take doxycycline twice a day for a week. […] If youre allergic to these medications, or they dont get rid of the infection, your provider may prescribe erythromycin or ofloxacin. […] You and your partner(s) should receive treatment. If only one partner receives treatment, you may continue to pass NGU back and forth to each other. […] It may take a week or two for your symptoms to go away after starting antibiotics. […] Schedule an appointment with a healthcare provider if you notice that you or your partner have any symptoms of NGU. Its also a good idea to get annual (yearly) or more frequent STI testing if youre sexually active with multiple partners.
- #57https://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=ut2089
Urethritis is usually treated with antibiotics. Most cases clear up with treatment. Proper treatment is very important. If you don’t treat it, the infection can lead to lasting damage of the urethra. Other parts of the urinary system can also be damaged. […] If your doctor prescribed antibiotics, take them as directed. Do not stop taking them just because you feel better. You need to take the full course of antibiotics. […] Do not have sex until you are done with treatment. If you do have sex, be sure to use a condom. Your sex partner or partners should be tested too if your urethritis was caused by an STI.
- #58 Urethritis Treatment & Management: Medical Care, Consultations, Preventionhttps://emedicine.medscape.com/article/438091-treatment
Symptoms of urethritis typically resolve spontaneously over time, regardless of treatment. Administer antibiotics to prevent morbidity and to reduce disease transmission to others. Treating recent sexual contacts (those having sexual contact with the patient within 60 days prior to symptom onset) also prevents reinfection of the index patient. […] Antibiotic therapy for urethritis should cover both gonococcal urethritis (GU) and nongonococcal urethritis (NGU). The choice of antibiotics should be based on effectiveness, adverse effects, cost, and compliance. In most situations, optimal treatment is with single-dose therapy administered in the emergency department or the physician’s office. […] Currently, the CDC recommends a single dose of ceftriaxone 500 mg IM (1 g IM in patients weighing 150 kg) for the treatment of GU. If ceftriaxone is unavailable, administer cefixime 800 mg orally in a single dose. If the patient has a cephalosporin allergy or a type 1 hypersensitivity reaction to penicillins, treat with gentamicin 240 mg IM plus azithromycin, 2 g orally. If chlamydial infection has not been excluded, treatment should also include doxycycline, 100 mg orally twice a day for 7 days.
- #59 Diagnosis and Treatment of Urethritis in Men | AAFPhttps://www.aafp.org/pubs/afp/issues/2010/0401/p873.html
Symptoms of urethritis in men typically include urethral discharge, penile itching or tingling, and dysuria. […] The goals of treatment include alleviating symptoms; preventing complications in the patient and his sexual partners; reducing the transmission of coinfections (particularly human immunodeficiency virus); identifying and treating the patient’s contacts; and encouraging behavioral changes that will reduce the risk of recurrence. […] The combination of azithromycin or doxycycline plus ceftriaxone or cefixime is considered first-line empiric therapy in patients with urethritis. […] The goals of treatment are to alleviate symptoms, prevent complications, reduce transmission of coinfections (particularly human immunodeficiency virus [HIV]), identify and treat contacts, and encourage behavioral changes to reduce the risk of recurrence.
- #60 Diagnosis and Treatment of Urethritis in Men | AAFPhttps://www.aafp.org/pubs/afp/issues/2010/0401/p873.html
Symptoms of urethritis in men typically include urethral discharge, penile itching or tingling, and dysuria. […] The goals of treatment include alleviating symptoms; preventing complications in the patient and his sexual partners; reducing the transmission of coinfections (particularly human immunodeficiency virus); identifying and treating the patient’s contacts; and encouraging behavioral changes that will reduce the risk of recurrence. […] The combination of azithromycin or doxycycline plus ceftriaxone or cefixime is considered first-line empiric therapy in patients with urethritis. […] The goals of treatment are to alleviate symptoms, prevent complications, reduce transmission of coinfections (particularly human immunodeficiency virus [HIV]), identify and treat contacts, and encourage behavioral changes to reduce the risk of recurrence.
- #61 Urethritis – StatPearls – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK537282/
Urethritis is a lower urinary tract infection that causes inflammation of the urethra. Testing and treatment are crucial to prevent the spread of STIs. Diagnosis depends on a comprehensive patient history, physical examination, and appropriate laboratory tests to confirm the presence of infection. Although symptoms may resolve spontaneously, antibiotic treatment is usually advised, particularly in cases where infection is confirmed or for sexual partners of affected individuals. […] Antibiotic treatment is recommended for the following situations: Patients with positive gram stain or cultures; Sexual contact with these patients; Patients with clinical urethritis who have negative gram stains or cultures but who are unlikely to return for follow-up. In cases where a specific cause cannot be identified, or follow-up is challenging, antibiotics that target both gonococcal and nongonococcal organisms are advised, regardless of symptoms. A recommended regimen includes ceftriaxone 250 mg administered intramuscularly, combined with either azithromycin 1 g administered orally as a single dose or doxycycline 100 mg taken orally twice daily for 7 days.
- #62 Diagnosis and Treatment of Urethritis in Men | AAFPhttps://www.aafp.org/pubs/afp/issues/2010/0401/p873.html
Symptoms of urethritis in men typically include urethral discharge, penile itching or tingling, and dysuria. […] The goals of treatment include alleviating symptoms; preventing complications in the patient and his sexual partners; reducing the transmission of coinfections (particularly human immunodeficiency virus); identifying and treating the patient’s contacts; and encouraging behavioral changes that will reduce the risk of recurrence. […] The combination of azithromycin or doxycycline plus ceftriaxone or cefixime is considered first-line empiric therapy in patients with urethritis. […] The goals of treatment are to alleviate symptoms, prevent complications, reduce transmission of coinfections (particularly human immunodeficiency virus [HIV]), identify and treat contacts, and encourage behavioral changes to reduce the risk of recurrence.