Szczepionka przeciw ospie wietrznej
Etiologia i przyczyny

Szczepionka przeciw ospie wietrznej, zawierająca żywy, atenuowany szczep Oka wirusa Varicella-Zoster (VZV), indukuje zarówno odpowiedź humoralną, jak i komórkową układu immunologicznego, zapewniając skuteczną ochronę przed pierwotnym zakażeniem i ciężkim przebiegiem choroby. Skuteczność szczepionki wynosi około 94,4% po jednej dawce i 98,3% po dwóch dawkach, z ochroną przed ciężkim przebiegiem na poziomie około 99%. Szczepionka jest zalecana dla dzieci od 12 miesiąca życia oraz osób bez dowodów odporności, a także jako profilaktyka poekspozycyjna podawana w ciągu 3-5 dni od kontaktu z wirusem. Od czasu wprowadzenia szczepień w USA w 1995 roku, liczba zachorowań spadła o 97%, a hospitalizacje i zgony odpowiednio o 93% i 94%.

Etiologia wirusa Varicella-Zoster jako przyczyna ospy wietrznej

Szczepionka przeciw ospie wietrznej jest skierowana przeciwko wirusowi ospy wietrznej i półpaśca (Varicella-Zoster Virus, VZV), który jest wirusem DNA należącym do rodziny herpeswirusów.12 VZV jest wysoce zakaźnym patogenem, który w przypadku pierwotnego zakażenia wywołuje ospę wietrzną (varicelę), a po reaktywacji, zwykle w późniejszym okresie życia, może powodować półpasiec (herpes zoster).34

Wirus Varicella-Zoster ma zdolność do ustanawiania zakażenia latentnego w układzie nerwowym po pierwotnej infekcji. Po przebyciu ospy wietrznej wirus pozostaje w uśpieniu w zwojach nerwowych, co jest kluczowym aspektem jego długiej historii ewolucyjnej.56 Ta zdolność do „znikania i ponownego pojawiania się” może stanowić przewagę ewolucyjną, umożliwiającą wirusowi przetrwanie przez miliony lat wraz z linią ewolucyjną człowieka.7

Charakterystyka wirusa i jego przenoszenie

VZV jest wirusem, który zakaża wyłącznie ludzi.8 Przenosi się głównie drogą powietrzną poprzez wdychanie kropelek zawierających wirusa, a także przez bezpośredni kontakt z płynem z pęcherzyków skórnych osób zakażonych.910 Wirus jest zakaźny od 1-2 dni przed pojawieniem się wysypki aż do momentu, gdy wszystkie pęcherzyki pokryją się strupami.11

Ospa wietrzna jest wysoce zakaźna, infekuje około 90% podatnych osób z kontaktu domowego i 10-35% osób z ograniczoną ekspozycją na wirusa.12 Przed wprowadzeniem szczepionki przeciw ospie wietrznej, niemal każde dziecko przechodziło tę chorobę, a 50% dzieci zarażało się nią przed ukończeniem 5 roku życia, a 90% przed ukończeniem 12 lat.13

Rozwój i charakterystyka szczepionki przeciw ospie wietrznej

Pierwsza żywa atenuowana szczepionka przeciwko ospie wietrznej została opracowana w Japonii przez zespół Takahashiego w latach 70. XX wieku.1415 Wirus do produkcji szczepionki, oznaczony jako szczep Oka, został wyizolowany z płynu pęcherzykowego od zdrowego 3-letniego chłopca zakażonego VZV.16

Szczepionka została po raz pierwszy dopuszczona do ogólnego stosowania w Japonii i Korei w 1988 roku, a następnie w Stanach Zjednoczonych w 1995 roku dla osób w wieku 12 miesięcy lub starszych.1718 Szczepionka Varivax (Merck Co., Inc.) była pierwszą szczepionką przeciwko ospie wietrznej zatwierdzoną w USA.19

Typy i skład szczepionek

Obecnie dostępne są dwa główne typy szczepionek zawierających antygen Varicella:

Obie szczepionki zawierają żywy, atenuowany (osłabiony) wirus Varicella-Zoster szczepu Oka.2425 Proces atenuacji polega na osłabieniu wirusa w warunkach laboratoryjnych, co przekształca go w formę, która zwykle nie jest wystarczająco silna, aby wywołać chorobę, ale wciąż jest w stanie wywołać odpowiedź immunologiczną.26

Wirus szczepionkowy został wyhodowany w komórkach fibroblastów świnki morskiej.27 Szczepionka zawiera także śladowe ilości neomycyny i żelatyny, które mogą być przyczyną reakcji alergicznych u niektórych osób.28

Mechanizm działania szczepionki przeciw ospie wietrznej

Szczepionka przeciw ospie wietrznej działa poprzez wprowadzenie do organizmu osłabionej formy wirusa Varicella-Zoster, co stymuluje układ odpornościowy do wytworzenia przeciwciał i komórek odpornościowych skierowanych przeciwko temu wirusowi.2930 Mechanizm działania szczepionki obejmuje zarówno odpowiedź humoralną (związaną z przeciwciałami), jak i komórkową układu immunologicznego.31

Gdy osłabiony wirus szczepionkowy dostaje się do organizmu, układ odpornościowy rozpoznaje go jako obcy i rozpoczyna produkcję specyficznych przeciwciał oraz komórek pamięci immunologicznej. Dzięki temu w przypadku późniejszego kontaktu z dzikim szczepem wirusa VZV, organizm jest przygotowany do szybkiej i skutecznej odpowiedzi immunologicznej, co zapobiega rozwojowi choroby lub znacznie łagodzi jej przebieg.3233

Odpowiedź immunologiczna po szczepieniu

Szczepionka przeciwko ospie wietrznej indukuje zarówno odpowiedź humoralną (przeciwciała), jak i komórkową, co zapewnia szeroki zakres ochrony immunologicznej.34 Przeciwciała skierowane przeciwko wirusowi Varicella-Zoster pomagają neutralizować cząsteczki wirusa, podczas gdy odpowiedź komórkowa jest kluczowa dla kontrolowania infekcji i zapobiegania reaktywacji wirusa w przyszłości.35

U około 2% zaszczepionych dzieci może wystąpić bardzo łagodna postać ospy wietrznej, zwykle nie więcej niż pięć do sześciu pęcherzyków. Jest to związane z odpowiedzią immunologiczną na osłabiony szczep wirusa zawartego w szczepionce.36

Skuteczność szczepionki przeciw ospie wietrznej

Skuteczność szczepionki przeciw ospie wietrznej różni się w zależności od liczby podanych dawek i badanej populacji. Ogólnie rzecz biorąc, szczepionka jest wysoko skuteczna w zapobieganiu zachorowaniom na ospę wietrzną, a szczególnie w zapobieganiu ciężkim przypadkom choroby.3738

Dwie dawki szczepionki przeciwko ospie wietrznej zapewniają ochronę przed zakażeniem u większości osób na całe życie.3940 Według raportów amerykańskich Centrów Kontroli i Zapobiegania Chorobom (CDC), dwie dawki szczepionki zapobiegają zachorowaniu w ponad 90% przypadków.41

Skuteczność jednej dawki vs. dwie dawki

Efektywność szczepionki przeciwko ospie wietrznej u dzieci szacuje się na 94,4% po podaniu jednej dawki i 98,3% po drugiej dawce.42 Natomiast pojedyncza dawka szczepionki zapewnia około 99% ochrony przed ciężkim przebiegiem choroby i 80% ochrony przed jakimkolwiek zakażeniem ospą wietrzną.43

Badania pokazują, że 9 na 10 dzieci zaszczepionych pojedynczą dawką rozwinie odporność przeciwko ospie wietrznej. Podanie dwóch zalecanych dawek daje jeszcze lepszą odpowiedź immunologiczną.44

Wpływ na populację

Od czasu wprowadzenia szczepionki przeciwko ospie wietrznej w 1995 roku w Stanach Zjednoczonych, liczba zachorowań na ospę wietrzną zmniejszyła się o około 97%.4546 Hospitalizacje i zgony z powodu ospy wietrznej spadły odpowiednio o 93% i 94%.47

Według szacunków, w ciągu pierwszych 25 lat programu szczepień przeciwko ospie wietrznej, szczepionka zapobiegła około 91 milionom przypadków zachorowań, 238 000 hospitalizacji i 2000 zgonów.48 Każdego roku szczepionka zapobiega około 3,5 milionom zakażeń i około 9000 hospitalizacji.49

Przypadki przełomowe zakażeń i zapobieganie półpaścowi

Przełomowe zakażenie ospą wietrzną definiuje się jako zakażenie dzikim typem wirusa VZV występujące ponad 42 dni po szczepieniu przeciwko ospie wietrznej; przełomowe zakażenie może wystąpić po 1 lub 2 dawkach szczepionki.50 U osób, które zostały zaszczepione, ale mimo to zachorują na ospę wietrzną, objawy są zwykle znacznie łagodniejsze, z mniejszą liczbą zmian skórnych i krótszym czasem zdrowienia niż u osób niezaszczepionych.5152

Niektóre osoby zaszczepione przeciwko ospie wietrznej mogą w późniejszym okresie życia zachorować na półpasiec (herpes zoster), ale jest to znacznie rzadsze po szczepieniu niż po naturalnym przebyciu ospy wietrznej.5354 Ryzyko zachorowania na półpasiec jest znacznie niższe wśród zaszczepionych dzieci, w tym także tych z obniżoną odpornością.55

Związek szczepionki z występowaniem półpaśca

Przez długi czas istniały obawy, że programy szczepień przeciwko ospie wietrznej mogą wpływać na zwiększenie liczby przypadków półpaśca u osób niezaszczepionych w późniejszym okresie życia.56 Mechanizm miał polegać na tym, że zmniejszenie częstości występowania ospy wietrznej w populacji ograniczy ekspozycję dorosłych na wirusa, co normalnie działa jak naturalny „booster” (wzmacniacz) odporności przeciwko reaktywacji VZV w postaci półpaśca.57

Jednak najnowsze badania epidemiologiczne na dużą skalę wykazały, że w Stanach Zjednoczonych i innych krajach nie zaobserwowano oczekiwanego wzrostu liczby przypadków półpaśca w ciągu ostatnich trzech dekad.58 Co więcej, najnowsze dane sugerują, że efekt ekspozycji na wirusa ospy wietrznej jako wzmacniacza odporności przeciwko półpaścowi utrzymuje się przez znacznie krótszy czas niż wcześniej sądzono.59

Badania wykazały również, że szczepionka przeciwko ospie wietrznej zmniejsza ryzyko półpaśca u dzieci o ponad połowę w porównaniu z przebyciem naturalnej infekcji, co stanowi dodatkową korzyść ze szczepienia.6061

Wskazania i przeciwwskazania do szczepienia

Szczepionka przeciwko ospie wietrznej jest zalecana dla wszystkich osób w wieku od 12 miesięcy, które nie mają dowodów na odporność przeciwko ospie wietrznej.6263 Szczególnie ważne jest zaszczepienie osób, które mają zwiększone ryzyko ciężkiego przebiegu choroby lub jej powikłań.64

Wskazania do szczepienia

Szczepienie przeciwko ospie wietrznej jest szczególnie zalecane dla następujących grup:

  • Dzieci, jako część rutynowego harmonogramu szczepień (pierwsza dawka w wieku 12-15 miesięcy, druga dawka w wieku 4-6 lat)6566
  • Osoby dorosłe i nastolatki bez odporności przeciwko ospie wietrznej6768
  • Osoby z kontaktu domowego z osobami z obniżoną odpornością69
  • Personel medyczny, pracownicy żłobków i placówek opieki nad osobami starszymi70
  • Osoby z przewlekłą chorobą nerek lub poddawane dializom71

Przeciwwskazania do szczepienia

Szczepionka przeciwko ospie wietrznej jest przeciwwskazana w następujących przypadkach:

Ponieważ zakażenie ospą wietrzną w czasie ciąży może szkodzić płodowi, ale skutki szczepienia nie zostały przetestowane na kobietach w ciąży, a wpływ na rozwój płodu jest obecnie nieznany, zaleca się unikanie szczepienia w czasie ciąży.7879

Profilaktyka poekspozycyjna

Szczepionka przeciwko ospie wietrznej może być stosowana jako profilaktyka poekspozycyjna u osób w wieku 12 miesięcy lub starszych, które nie mają dowodów na odporność przeciwko ospie wietrznej, w ciągu 3-5 dni po ekspozycji na wirusa.8081

Dane ze Stanów Zjednoczonych i Japonii z różnych środowisk wskazują, że szczepionka przeciwko ospie wietrznej jest skuteczna w 70% do 100% w zapobieganiu chorobie lub łagodzeniu jej przebiegu, jeśli zostanie podana w ciągu 3 dni, a możliwe, że nawet do 5 dni po ekspozycji.8283

Immunoglobulina przeciw varicella-zoster

Osobom z osłabionym układem odpornościowym oraz kobietom w ciąży bez dowodów na odporność przeciwko VZV, które były narażone na kontakt z wirusem, można podać immunoglobulinę przeciwko wirusowi varicella-zoster (VZIG), aby zmniejszyć ryzyko powikłań choroby.8485

VZIG zawiera przeciwciała zwalczające wirusa ospy wietrznej i może złagodzić objawy ospy wietrznej oraz zmniejszyć ryzyko powikłań u osób narażonych na zakażenie.86 W 2006 roku nowy produkt o nazwie VariZIG stał się dostępny do ochrony pacjentów bez dowodów na odporność przeciwko ospie wietrznej, którzy są narażeni na wysokie ryzyko ciężkiego przebiegu choroby i powikłań, a byli narażeni na kontakt z ospą wietrzną.87

Niepożądane odczyny poszczepienne

Szczepionka przeciwko ospie wietrznej jest ogólnie bezpieczna, a poważne działania niepożądane są rzadkie.88 Większość reakcji poszczepiennych jest łagodna i krótkotrwała.

Częste łagodne reakcje

Najczęstsze łagodne reakcje poszczepienne obejmują:

  • Ból, zaczerwienienie lub obrzęk w miejscu wstrzyknięcia89
  • Gorączka90
  • Łagodna wysypka podobna do ospy wietrznej (u około 7% osób), zwykle z kilkoma krostkami9192

Rzadkie poważne reakcje

Rzadkie, ale poważne reakcje poszczepienne mogą obejmować:

Nieprawidłowo podana szczepionka może powodować poważne działania niepożądane lub urazy barku.98

Komitet ds. oceny bezpieczeństwa szczepionek stwierdził przekonujące dowody na związek przyczynowy między szczepionką przeciwko ospie wietrznej a rozsianym zakażeniem wirusem Oka bez zajęcia innych narządów oraz reaktywacją wirusa szczepionkowego z następowym zakażeniem prowadzącym do zapalenia opon mózgowych lub zapalenia mózgu.99 Jednak te poważne powikłania są niezwykle rzadkie, a korzyści ze szczepienia przeciwko ospie wietrznej znacznie przewyższają ryzyko.100

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  1. 09.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Clinical Overview of Chickenpox (Varicella) | Chickenpox (Varicella) | CDC
    https://www.cdc.gov/chickenpox/hcp/clinical-overview/index.html
    Varicella (chickenpox) is an acute infectious disease caused by varicella-zoster virus (VZV). […] Varicella is highly caused by varicella-zoster virus (VZV), which is a DNA virus that is a member of the herpesvirus group. Primary infection with VZV causes varicella. […] The most effective prevention for varicella is chickenpox vaccination. […] The varicella vaccination program has dramatically decreased virus circulation and increased community protection. […] The risk of shingles is significantly lower among vaccinated children, including those who are immunocompromised. […] Chickenpox is a highly contagious disease caused by the varicella-zoster virus (VZV).
  • #2 Varicella Virus Vaccine – Adverse Effects of Vaccines – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK190012/
    Varicella, more commonly known as chickenpox, is caused by the human alpha herpesvirus varicella zoster virus (VZV). Transmitted through direct contact with or inhalation of infectious fluid, VZV is highly contagious and infects approximately 90 percent of susceptible household contacts and 10 to 35 percent of individuals with limited exposure (Arvin, 1996; Ross et al., 1962). […] The first live attenuated varicella vaccine was developed and tested in Japan by Takahashi and colleagues in the 1970s. The virus, designated Oka strain, was isolated from vesicular fluid of a healthy 3-year-old boy infected with VZV (Takahashi et al., 1975). […] In 1995, the live, attenuated virus vaccine, Varivax (Merck Co., Inc.) was licensed in the United States for use in healthy individuals greater than 12 months of age (CDC, 2007).
  • #3 Everything you need to know about chickenpox and why more countries don’t use the vaccine | University of Oxford
    https://www.ox.ac.uk/research/everything-you-need-know-about-chickenpox-and-why-more-countries-don%E2%80%99t-use-vaccine
    Recent calls for the introduction of a vaccine against chickenpox (varicella-zoster virus infection) following a severe case of the disease in Cambridge, England may surprise many parents who consider the disease to be a mild illness that everyone gets. […] The chickenpox vaccine is usually administered to children at the same time as the MMR vaccine (around 12 months of age with a booster at three-and-a-half to five years of age in some countries) and effectively prevents severe chickenpox. […] Nevertheless, the burden of severe and life-threatening complications has essentially disappeared in countries where the vaccine is routinely used. […] In the last review of the chickenpox vaccine by the committee which advises the government on vaccines (the Joint Committee on Vaccination and Immunisation, JCVI), the future modelling of the impact of vaccination indicated that there could be an increase in the rate of shingles in adults over time, which would make the vaccine programme not cost-effective. […] Put simply, the conclusion of the previous review was that it would not be cost-effective for the NHS to immunise children against chickenpox.
  • #4 Varicella (Chickenpox) Vaccine – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK441946/
    Varicella or chickenpox is a common and highly contagious exanthematic disease caused by the varicella-zoster virus that, during primary infection, can establish latency. […] The varicella-zoster virus is a vaccine-preventable disease, and the FDA approves the live varicella virus vaccine to provide immunity for preventing varicella in individuals 12 months and older. […] Current vaccines against varicella and herpes zoster are not 100% efficacious; it is between 70% and 90% effective at preventing varicella and over 95% effective at preventing severe varicella. […] The varicella-zoster vaccine contains live attenuated varicella-zoster vaccine (Oka strain). This vaccine induces both humoral and cell-mediated immune responses. […] The varicella vaccine is contraindicated in individuals who have a severe allergy or have had an anaphylactic reaction to neomycin or gelatin, which are components of this vaccine, or to the previous dose of a varicella-containing vaccine. […] Maternal varicella infection has been shown to harm the fetus, but the vaccination effects have not been tested on pregnant women, and the effects on fetal development are currently unknown.
  • #5 The chickenpox virus has a fascinating evolutionary history that continues to affect peoples’ health today: 2021 News: News: News & Events: Department of Biology: Indiana University Bloomington
    https://biology.indiana.edu/news-events/news/2021/foster-chickenpox-fascinating-evolutionary-history.html
    The chickenpox virus has a fascinating evolutionary history that continues to affect peoples health today. […] The virus that causes chickenpox is one of these, coexisting with the human evolutionary line for millions of years. […] Chickenpox is a childhood disease, and until a couple of decades ago, nearly all children in the United States got it. […] The viruss ability to do this disappearing-and-reappearing trick may be the key to its long evolutionary history. […] The virus that causes both chickenpox and shingles, varicella-zoster, is only known to infect humans. […] Infection with chickenpox typically provides lifelong immunity to reinfection. […] Varicella-zoster has a long, slow evolutionary history. […] The ability to enter a latent state may have given varicella-zoster a survival advantage. […] With effective vaccines against both chickenpox and shingles now available, I believe that the countries with high vaccination rates could eventually be free of both of the diseases caused by varicella-zosterultimately making the chickenpox-shingles duo go the way of the dinosaurs.
  • #6
    https://www.aurorahealthcare.org/services/primary-care/preventive-care/vaccinations/chickenpox-varicella
    The chickenpox vaccine is a shot that helps protect children and adults from getting sick with chickenpox. Chickenpox is a contagious disease caused by the varicella-zoster virus. […] Varicella-zoster is a virus that causes chickenpox. Once you have had chickenpox, the varicella-zoster virus remains in your body but is inactive. […] The chickenpox vaccine is a live vaccine, meaning it contains a weakened form of the varicella-zoster virus. There is a small risk that live vaccines could cause infection in people with a weakened or compromised immune system.
  • #7 The chickenpox virus has a fascinating evolutionary history that continues to affect peoples’ health today: 2021 News: News: News & Events: Department of Biology: Indiana University Bloomington
    https://biology.indiana.edu/news-events/news/2021/foster-chickenpox-fascinating-evolutionary-history.html
    The chickenpox virus has a fascinating evolutionary history that continues to affect peoples health today. […] The virus that causes chickenpox is one of these, coexisting with the human evolutionary line for millions of years. […] Chickenpox is a childhood disease, and until a couple of decades ago, nearly all children in the United States got it. […] The viruss ability to do this disappearing-and-reappearing trick may be the key to its long evolutionary history. […] The virus that causes both chickenpox and shingles, varicella-zoster, is only known to infect humans. […] Infection with chickenpox typically provides lifelong immunity to reinfection. […] Varicella-zoster has a long, slow evolutionary history. […] The ability to enter a latent state may have given varicella-zoster a survival advantage. […] With effective vaccines against both chickenpox and shingles now available, I believe that the countries with high vaccination rates could eventually be free of both of the diseases caused by varicella-zosterultimately making the chickenpox-shingles duo go the way of the dinosaurs.
  • #8 The chickenpox virus has a fascinating evolutionary history that continues to affect peoples’ health today: 2021 News: News: News & Events: Department of Biology: Indiana University Bloomington
    https://biology.indiana.edu/news-events/news/2021/foster-chickenpox-fascinating-evolutionary-history.html
    The chickenpox virus has a fascinating evolutionary history that continues to affect peoples health today. […] The virus that causes chickenpox is one of these, coexisting with the human evolutionary line for millions of years. […] Chickenpox is a childhood disease, and until a couple of decades ago, nearly all children in the United States got it. […] The viruss ability to do this disappearing-and-reappearing trick may be the key to its long evolutionary history. […] The virus that causes both chickenpox and shingles, varicella-zoster, is only known to infect humans. […] Infection with chickenpox typically provides lifelong immunity to reinfection. […] Varicella-zoster has a long, slow evolutionary history. […] The ability to enter a latent state may have given varicella-zoster a survival advantage. […] With effective vaccines against both chickenpox and shingles now available, I believe that the countries with high vaccination rates could eventually be free of both of the diseases caused by varicella-zosterultimately making the chickenpox-shingles duo go the way of the dinosaurs.
  • #9 Shingles and chickenpox (Varicella-zoster virus) Information | Mount Sinai – New York
    https://www.mountsinai.org/health-library/report/shingles-and-chickenpox-varicella-zoster-virus
    Shingles and chickenpox are both caused by a single virus of the herpes family, known as the Varicella-zoster virus (VZV). VZV causes two different illnesses: Varicella, or chickenpox, develops after an individual is exposed to VZV for the first time. […] Most people get chickenpox from exposure to other people with chickenpox. The varicella virus is most often spread through sneezing, coughing, and breathing. It is so contagious that few non-immunized people escape chickenpox when they are exposed to someone with the disease. […] When people with chickenpox cough or sneeze, they expel tiny droplets that carry the varicella virus. If a person who has never had chickenpox or never been vaccinated inhales these particles, the virus enters the lungs. From here it passes into the bloodstream. […] People can also catch chickenpox from direct contact with a shingles rash if they have not been immunized by vaccination or by a previous bout of chickenpox. […] Shingles can develop only from a reactivation of the varicella-zoster virus in a person who has previously had chickenpox.
  • #10 Varicella (chickenpox) vaccines: Canadian Immunization Guide – Canada.ca
    https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/page-24-varicella-chickenpox-vaccine.html
    Varicella (chickenpox) is a generalized viral disease caused by varicella zoster virus (VZV), a deoxyribonucleic acid (DNA virus) of the Herpesvirus family. […] VZV is spread by the airborne route, as well as by direct contact with virus shed from skin lesions. […] The risk of varicella infection severity increases with age. […] The following groups of individuals are considered to be at increased risk of severe varicella: Newborn infants of mothers who develop varicella from 5 days before until 48 hours after delivery; Neonates in intensive care settings born at less than 28 weeks of gestation or weighing 1,000 g or less at birth, regardless of their mothers’ evidence of immunity; Susceptible pregnant women; Susceptible immunocompromised persons, including HIV-infected persons with CD4 cell count 200 106/L or CD4 percentage 15%. […] Varicella vaccine is recommended for susceptible individuals with chronic renal disease or undergoing dialysis. […] Individuals who are immunocompromised, either due to underlying conditions or immunosuppressive agents, are more susceptible to infections including varicella.
  • #11 Chickenpox: Symptoms & Causes | NewYork-Presbyterian
    https://www.nyp.org/primary-care/chickenpox
    Chickenpox is a highly contagious infection characterized by a fever and rash caused by a virus. The varicella-zoster virus causes chickenpox. […] The varicella virus is highly contagious and is transmitted easily. Things to keep in mind include: A contagious virus causes chickenpox. Most cases of chickenpox result from exposure to an infected person. The virus is contagious for a day or two before blisters appear on the skin. The virus remains contagious until all blisters have scabbed over. Coughing or sneezing can spread the chickenpox virus. The virus can spread through contact with saliva or fluid from blisters. […] The chickenpox vaccine is given in two doses and prevents chickenpox in over 90% of the people who receive it.
  • #12 Varicella Virus Vaccine – Adverse Effects of Vaccines – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK190012/
    Varicella, more commonly known as chickenpox, is caused by the human alpha herpesvirus varicella zoster virus (VZV). Transmitted through direct contact with or inhalation of infectious fluid, VZV is highly contagious and infects approximately 90 percent of susceptible household contacts and 10 to 35 percent of individuals with limited exposure (Arvin, 1996; Ross et al., 1962). […] The first live attenuated varicella vaccine was developed and tested in Japan by Takahashi and colleagues in the 1970s. The virus, designated Oka strain, was isolated from vesicular fluid of a healthy 3-year-old boy infected with VZV (Takahashi et al., 1975). […] In 1995, the live, attenuated virus vaccine, Varivax (Merck Co., Inc.) was licensed in the United States for use in healthy individuals greater than 12 months of age (CDC, 2007).
  • #13 Varicella (chickenpox) vaccines: Canadian Immunization Guide – Canada.ca
    https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/page-24-varicella-chickenpox-vaccine.html
    Primary varicella zoster virus infection causes varicella (chickenpox) and reactivated infection results in herpes zoster (shingles). […] Complications are more common in adolescents, adults and immunocompromised individuals. Individuals with impaired immunity are at risk of severe varicella and death. […] Varicella-containing vaccine is available as univalent varicella vaccine or combined multivalent measles-mumps-rubella-varicella (MMRV) vaccine. […] The efficacy of varicella vaccines in children is estimated to be 94.4% following a single dose and 98.3% following a second dose. […] In countries without vaccination programs, varicella is mainly a disease of childhood, developing in 50% of children by the age of 5 years and 90% by the age of 12 years. […] Since the introduction of immunization programs in Canada, there has been a decrease in the burden of varicella.
  • #14 Chapter 22: Varicella | Pink Book | CDC
    https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-22-varicella.html
    Varicella is an acute infectious disease caused by varicella-zoster virus (VZV). […] A live, attenuated varicella vaccine was developed in Japan in the 1970s. […] Varicella vaccine was licensed for general use in Japan and Korea in 1988, and in the United States in 1995 for persons age 12 months or older. […] Primary infection with VZV results in varicella. […] Breakthrough varicella is defined as varicella due to infection with wild-type VZV occurring more than 42 days after varicella vaccination; breakthrough infection can occur after 1 or 2 doses of vaccine. […] The risk of complications from varicella varies with age. […] Since 1995, when the varicella vaccination program was implemented, hospitalizations and deaths from varicella have declined in the United States 93% and 94%, respectively.
  • #15 Varicella Virus Vaccine – Adverse Effects of Vaccines – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK190012/
    Varicella, more commonly known as chickenpox, is caused by the human alpha herpesvirus varicella zoster virus (VZV). Transmitted through direct contact with or inhalation of infectious fluid, VZV is highly contagious and infects approximately 90 percent of susceptible household contacts and 10 to 35 percent of individuals with limited exposure (Arvin, 1996; Ross et al., 1962). […] The first live attenuated varicella vaccine was developed and tested in Japan by Takahashi and colleagues in the 1970s. The virus, designated Oka strain, was isolated from vesicular fluid of a healthy 3-year-old boy infected with VZV (Takahashi et al., 1975). […] In 1995, the live, attenuated virus vaccine, Varivax (Merck Co., Inc.) was licensed in the United States for use in healthy individuals greater than 12 months of age (CDC, 2007).
  • #16 Varicella Virus Vaccine – Adverse Effects of Vaccines – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK190012/
    Varicella, more commonly known as chickenpox, is caused by the human alpha herpesvirus varicella zoster virus (VZV). Transmitted through direct contact with or inhalation of infectious fluid, VZV is highly contagious and infects approximately 90 percent of susceptible household contacts and 10 to 35 percent of individuals with limited exposure (Arvin, 1996; Ross et al., 1962). […] The first live attenuated varicella vaccine was developed and tested in Japan by Takahashi and colleagues in the 1970s. The virus, designated Oka strain, was isolated from vesicular fluid of a healthy 3-year-old boy infected with VZV (Takahashi et al., 1975). […] In 1995, the live, attenuated virus vaccine, Varivax (Merck Co., Inc.) was licensed in the United States for use in healthy individuals greater than 12 months of age (CDC, 2007).
  • #17 Chapter 22: Varicella | Pink Book | CDC
    https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-22-varicella.html
    Varicella is an acute infectious disease caused by varicella-zoster virus (VZV). […] A live, attenuated varicella vaccine was developed in Japan in the 1970s. […] Varicella vaccine was licensed for general use in Japan and Korea in 1988, and in the United States in 1995 for persons age 12 months or older. […] Primary infection with VZV results in varicella. […] Breakthrough varicella is defined as varicella due to infection with wild-type VZV occurring more than 42 days after varicella vaccination; breakthrough infection can occur after 1 or 2 doses of vaccine. […] The risk of complications from varicella varies with age. […] Since 1995, when the varicella vaccination program was implemented, hospitalizations and deaths from varicella have declined in the United States 93% and 94%, respectively.
  • #18 Varicella Virus Vaccine – Adverse Effects of Vaccines – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK190012/
    Varicella, more commonly known as chickenpox, is caused by the human alpha herpesvirus varicella zoster virus (VZV). Transmitted through direct contact with or inhalation of infectious fluid, VZV is highly contagious and infects approximately 90 percent of susceptible household contacts and 10 to 35 percent of individuals with limited exposure (Arvin, 1996; Ross et al., 1962). […] The first live attenuated varicella vaccine was developed and tested in Japan by Takahashi and colleagues in the 1970s. The virus, designated Oka strain, was isolated from vesicular fluid of a healthy 3-year-old boy infected with VZV (Takahashi et al., 1975). […] In 1995, the live, attenuated virus vaccine, Varivax (Merck Co., Inc.) was licensed in the United States for use in healthy individuals greater than 12 months of age (CDC, 2007).
  • #19 Varicella Virus Vaccine – Adverse Effects of Vaccines – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK190012/
    Varicella, more commonly known as chickenpox, is caused by the human alpha herpesvirus varicella zoster virus (VZV). Transmitted through direct contact with or inhalation of infectious fluid, VZV is highly contagious and infects approximately 90 percent of susceptible household contacts and 10 to 35 percent of individuals with limited exposure (Arvin, 1996; Ross et al., 1962). […] The first live attenuated varicella vaccine was developed and tested in Japan by Takahashi and colleagues in the 1970s. The virus, designated Oka strain, was isolated from vesicular fluid of a healthy 3-year-old boy infected with VZV (Takahashi et al., 1975). […] In 1995, the live, attenuated virus vaccine, Varivax (Merck Co., Inc.) was licensed in the United States for use in healthy individuals greater than 12 months of age (CDC, 2007).
  • #20 Varicella (Chickenpox) Vaccine – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK441946/
    Varicella or chickenpox is a common and highly contagious exanthematic disease caused by the varicella-zoster virus that, during primary infection, can establish latency. […] The varicella-zoster virus is a vaccine-preventable disease, and the FDA approves the live varicella virus vaccine to provide immunity for preventing varicella in individuals 12 months and older. […] Current vaccines against varicella and herpes zoster are not 100% efficacious; it is between 70% and 90% effective at preventing varicella and over 95% effective at preventing severe varicella. […] The varicella-zoster vaccine contains live attenuated varicella-zoster vaccine (Oka strain). This vaccine induces both humoral and cell-mediated immune responses. […] The varicella vaccine is contraindicated in individuals who have a severe allergy or have had an anaphylactic reaction to neomycin or gelatin, which are components of this vaccine, or to the previous dose of a varicella-containing vaccine. […] Maternal varicella infection has been shown to harm the fetus, but the vaccination effects have not been tested on pregnant women, and the effects on fetal development are currently unknown.
  • #21 Varicella (chickenpox) vaccines: Canadian Immunization Guide – Canada.ca
    https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/page-24-varicella-chickenpox-vaccine.html
    Primary varicella zoster virus infection causes varicella (chickenpox) and reactivated infection results in herpes zoster (shingles). […] Complications are more common in adolescents, adults and immunocompromised individuals. Individuals with impaired immunity are at risk of severe varicella and death. […] Varicella-containing vaccine is available as univalent varicella vaccine or combined multivalent measles-mumps-rubella-varicella (MMRV) vaccine. […] The efficacy of varicella vaccines in children is estimated to be 94.4% following a single dose and 98.3% following a second dose. […] In countries without vaccination programs, varicella is mainly a disease of childhood, developing in 50% of children by the age of 5 years and 90% by the age of 12 years. […] Since the introduction of immunization programs in Canada, there has been a decrease in the burden of varicella.
  • #22 Chickenpox Vaccine (Varicella Vaccine) Side Effects & Other Facts
    https://my.clevelandclinic.org/health/treatments/22136-chickenpox-vaccine
    The chickenpox vaccine is a two-dose series of shots that protect you or your child from chickenpox. […] Another name for the chickenpox vaccine is the varicella vaccine. Thats because the varicella-zoster virus causes chickenpox. […] The chickenpox vaccine is part of the childhood immunization schedule. […] The chickenpox vaccine is very effective. Two doses provide lifelong protection against infection for most people. […] Yes. Both varicella vaccines (Varivax and ProQuad) are live, attenuated vaccines. This type of vaccine uses an attenuated, or weakened virus, to stimulate an immune response. […] Researchers start with a wild virus, or a virus that exists out in the world, and weaken it in a lab. This process transforms the virus so its typically not strong enough to make you sick but spurs an immune response.
  • #23 Chickenpox – immunisation | Better Health Channel
    https://www.betterhealth.vic.gov.au/health/healthyliving/chickenpox-immunisation
    Chickenpox (also called varicella) is caused by the varicella-zoster virus (VZV). It is a highly infectious disease that usually causes an itchy red rash with blisters. […] Immunisation against chickenpox is included in the combination measles, mumps, rubella and varicella (MMRV) vaccine recommended for children at 18 months of age. […] Both the combination MMRV vaccine and the chickenpox vaccine contain a very weakened form of chickenpox virus that works by causing the body to produce its own antibodies to protect against the virus.
  • #24 Chickenpox Vaccine (Varicella Vaccine) Side Effects & Other Facts
    https://my.clevelandclinic.org/health/treatments/22136-chickenpox-vaccine
    The chickenpox vaccine is a two-dose series of shots that protect you or your child from chickenpox. […] Another name for the chickenpox vaccine is the varicella vaccine. Thats because the varicella-zoster virus causes chickenpox. […] The chickenpox vaccine is part of the childhood immunization schedule. […] The chickenpox vaccine is very effective. Two doses provide lifelong protection against infection for most people. […] Yes. Both varicella vaccines (Varivax and ProQuad) are live, attenuated vaccines. This type of vaccine uses an attenuated, or weakened virus, to stimulate an immune response. […] Researchers start with a wild virus, or a virus that exists out in the world, and weaken it in a lab. This process transforms the virus so its typically not strong enough to make you sick but spurs an immune response.
  • #25 Varicella (Chickenpox) Vaccine – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK441946/
    Varicella or chickenpox is a common and highly contagious exanthematic disease caused by the varicella-zoster virus that, during primary infection, can establish latency. […] The varicella-zoster virus is a vaccine-preventable disease, and the FDA approves the live varicella virus vaccine to provide immunity for preventing varicella in individuals 12 months and older. […] Current vaccines against varicella and herpes zoster are not 100% efficacious; it is between 70% and 90% effective at preventing varicella and over 95% effective at preventing severe varicella. […] The varicella-zoster vaccine contains live attenuated varicella-zoster vaccine (Oka strain). This vaccine induces both humoral and cell-mediated immune responses. […] The varicella vaccine is contraindicated in individuals who have a severe allergy or have had an anaphylactic reaction to neomycin or gelatin, which are components of this vaccine, or to the previous dose of a varicella-containing vaccine. […] Maternal varicella infection has been shown to harm the fetus, but the vaccination effects have not been tested on pregnant women, and the effects on fetal development are currently unknown.
  • #26 Chickenpox Vaccine (Varicella Vaccine) Side Effects & Other Facts
    https://my.clevelandclinic.org/health/treatments/22136-chickenpox-vaccine
    The chickenpox vaccine is a two-dose series of shots that protect you or your child from chickenpox. […] Another name for the chickenpox vaccine is the varicella vaccine. Thats because the varicella-zoster virus causes chickenpox. […] The chickenpox vaccine is part of the childhood immunization schedule. […] The chickenpox vaccine is very effective. Two doses provide lifelong protection against infection for most people. […] Yes. Both varicella vaccines (Varivax and ProQuad) are live, attenuated vaccines. This type of vaccine uses an attenuated, or weakened virus, to stimulate an immune response. […] Researchers start with a wild virus, or a virus that exists out in the world, and weaken it in a lab. This process transforms the virus so its typically not strong enough to make you sick but spurs an immune response.
  • #27 Varicella (Chickenpox): The Disease & Vaccines | Children’s Hospital of Philadelphia
    https://www.chop.edu/vaccine-education-center/vaccine-details/varicella-vaccine
    Chickenpox is an infection caused by the varicella virus, and it is highly contagious. […] Chickenpox infections can have severe complications. About 1 of every 1,000 children infected with varicella will develop severe pneumonia (infection of the lungs) or encephalitis (infection of the brain). […] The varicella vaccine is a live, „weakened” form of natural varicella virus. […] The vaccine virus was also grown in guinea pig fibroblast cells. […] The varicella vaccine is given to children between 12 and 15 months and again between 4 and 6 years of age. […] Since the introduction of the single-dose varicella vaccine into the United States in 1995, and the second-dose vaccine in 2006, the number of people infected with chickenpox has decreased by about 97%. […] The varicella vaccine does not have serious side effects. Therefore, the benefits of the varicella vaccine clearly outweigh its risks.
  • #28 Varicella (Chickenpox) Vaccine – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK441946/
    Varicella or chickenpox is a common and highly contagious exanthematic disease caused by the varicella-zoster virus that, during primary infection, can establish latency. […] The varicella-zoster virus is a vaccine-preventable disease, and the FDA approves the live varicella virus vaccine to provide immunity for preventing varicella in individuals 12 months and older. […] Current vaccines against varicella and herpes zoster are not 100% efficacious; it is between 70% and 90% effective at preventing varicella and over 95% effective at preventing severe varicella. […] The varicella-zoster vaccine contains live attenuated varicella-zoster vaccine (Oka strain). This vaccine induces both humoral and cell-mediated immune responses. […] The varicella vaccine is contraindicated in individuals who have a severe allergy or have had an anaphylactic reaction to neomycin or gelatin, which are components of this vaccine, or to the previous dose of a varicella-containing vaccine. […] Maternal varicella infection has been shown to harm the fetus, but the vaccination effects have not been tested on pregnant women, and the effects on fetal development are currently unknown.
  • #29 Varicella (chickenpox) Vaccine > Clinical Keywords > Yale Medicine
    https://www.yalemedicine.org/clinical-keywords/varicella-vaccine
    The varicella (chickenpox) vaccine is an immunization that helps protect against the varicella-zoster virus, which causes chickenpox. […] It is a live attenuated vaccine that stimulates the immune system to produce antibodies against the virus, reducing the risk of infection and severity of the disease.
  • #30 Chickenpox (Varicella) Vaccine: Schedule and Side Effects
    https://www.webmd.com/children/vaccines/chickenpox-varicella-vaccine
    The chickenpox vaccine is a shot that can protect nearly anyone who receives the vaccine from catching chickenpox. It’s also called the varicella vaccine because chickenpox is caused by the varicella-zoster virus. The vaccine is made from a live but weakened, or attenuated, virus. […] Although the virus in the chickenpox vaccine is generally incapable of causing a disease, it still stimulates a response from the body’s immune system. That response is what gives someone who’s had a shot for chickenpox immunity or protection from the illness. […] About 2% of the children who are vaccinated develop a very mild case of chickenpox, usually with no more than five to six blisters. It is also possible for a person who has been vaccinated for chickenpox to develop chickenpox at some later point in life. When that happens, the disease is almost always milder and the recovery more rapid than for people who have not had the shots.
  • #31 Varicella (Chickenpox) Vaccine – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK441946/
    Varicella or chickenpox is a common and highly contagious exanthematic disease caused by the varicella-zoster virus that, during primary infection, can establish latency. […] The varicella-zoster virus is a vaccine-preventable disease, and the FDA approves the live varicella virus vaccine to provide immunity for preventing varicella in individuals 12 months and older. […] Current vaccines against varicella and herpes zoster are not 100% efficacious; it is between 70% and 90% effective at preventing varicella and over 95% effective at preventing severe varicella. […] The varicella-zoster vaccine contains live attenuated varicella-zoster vaccine (Oka strain). This vaccine induces both humoral and cell-mediated immune responses. […] The varicella vaccine is contraindicated in individuals who have a severe allergy or have had an anaphylactic reaction to neomycin or gelatin, which are components of this vaccine, or to the previous dose of a varicella-containing vaccine. […] Maternal varicella infection has been shown to harm the fetus, but the vaccination effects have not been tested on pregnant women, and the effects on fetal development are currently unknown.
  • #32 Varicella Vaccine And Covid Vaccine | Travelvax
    https://www.travelvax.com.au/latest-news/varicella-vaccine-and-covid-vaccine
    The varicella vaccine, commonly known as the chickenpox vaccine, plays a crucial role in preventing varicella-zoster virus (VZV) (herpes zoster) infection. This vaccine is a live attenuated vaccine, meaning it contains a weakened form of the virus that causes chickenpox. […] The varicella vaccine works by introducing the weakened virus into the body. This prompts the immune system to recognise the virus as foreign and mount a defence. […] The varicella vaccine has proven to be highly effective in preventing chickenpox. In addition to protecting individuals from the primary infection, it also reduces the severity of symptoms in those who may still contract the virus after vaccination.
  • #33 Chickenpox (Varicella) Vaccine: Schedule and Side Effects
    https://www.webmd.com/children/vaccines/chickenpox-varicella-vaccine
    The chickenpox vaccine is a shot that can protect nearly anyone who receives the vaccine from catching chickenpox. It’s also called the varicella vaccine because chickenpox is caused by the varicella-zoster virus. The vaccine is made from a live but weakened, or attenuated, virus. […] Although the virus in the chickenpox vaccine is generally incapable of causing a disease, it still stimulates a response from the body’s immune system. That response is what gives someone who’s had a shot for chickenpox immunity or protection from the illness. […] About 2% of the children who are vaccinated develop a very mild case of chickenpox, usually with no more than five to six blisters. It is also possible for a person who has been vaccinated for chickenpox to develop chickenpox at some later point in life. When that happens, the disease is almost always milder and the recovery more rapid than for people who have not had the shots.
  • #34 Varicella (Chickenpox) Vaccine – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK441946/
    Varicella or chickenpox is a common and highly contagious exanthematic disease caused by the varicella-zoster virus that, during primary infection, can establish latency. […] The varicella-zoster virus is a vaccine-preventable disease, and the FDA approves the live varicella virus vaccine to provide immunity for preventing varicella in individuals 12 months and older. […] Current vaccines against varicella and herpes zoster are not 100% efficacious; it is between 70% and 90% effective at preventing varicella and over 95% effective at preventing severe varicella. […] The varicella-zoster vaccine contains live attenuated varicella-zoster vaccine (Oka strain). This vaccine induces both humoral and cell-mediated immune responses. […] The varicella vaccine is contraindicated in individuals who have a severe allergy or have had an anaphylactic reaction to neomycin or gelatin, which are components of this vaccine, or to the previous dose of a varicella-containing vaccine. […] Maternal varicella infection has been shown to harm the fetus, but the vaccination effects have not been tested on pregnant women, and the effects on fetal development are currently unknown.
  • #35 What Is Chicken Pox Vaccine?
    https://www.icliniq.com/articles/drug-and-supplements/chickenpox-vaccine
    The varicella-zoster virus, which causes chickenpox, is protected against by the chickenpox vaccine. […] The chickenpox vaccine is made from live but weakened or attenuated viruses. […] The chickenpox vaccine is very effective in preventing the disease. […] The chickenpox vaccine stimulates the immune system to produce antibodies that will help in protecting against chickenpox.
  • #36 Chickenpox (Varicella) Vaccine: Schedule and Side Effects
    https://www.webmd.com/children/vaccines/chickenpox-varicella-vaccine
    The chickenpox vaccine is a shot that can protect nearly anyone who receives the vaccine from catching chickenpox. It’s also called the varicella vaccine because chickenpox is caused by the varicella-zoster virus. The vaccine is made from a live but weakened, or attenuated, virus. […] Although the virus in the chickenpox vaccine is generally incapable of causing a disease, it still stimulates a response from the body’s immune system. That response is what gives someone who’s had a shot for chickenpox immunity or protection from the illness. […] About 2% of the children who are vaccinated develop a very mild case of chickenpox, usually with no more than five to six blisters. It is also possible for a person who has been vaccinated for chickenpox to develop chickenpox at some later point in life. When that happens, the disease is almost always milder and the recovery more rapid than for people who have not had the shots.
  • #37 Chickenpox Vaccine (Varicella Vaccine) Side Effects & Other Facts
    https://my.clevelandclinic.org/health/treatments/22136-chickenpox-vaccine
    The chickenpox vaccine is a two-dose series of shots that protect you or your child from chickenpox. […] Another name for the chickenpox vaccine is the varicella vaccine. Thats because the varicella-zoster virus causes chickenpox. […] The chickenpox vaccine is part of the childhood immunization schedule. […] The chickenpox vaccine is very effective. Two doses provide lifelong protection against infection for most people. […] Yes. Both varicella vaccines (Varivax and ProQuad) are live, attenuated vaccines. This type of vaccine uses an attenuated, or weakened virus, to stimulate an immune response. […] Researchers start with a wild virus, or a virus that exists out in the world, and weaken it in a lab. This process transforms the virus so its typically not strong enough to make you sick but spurs an immune response.
  • #38 Varicella (Chickenpox): The Disease & Vaccines | Children’s Hospital of Philadelphia
    https://www.chop.edu/vaccine-education-center/vaccine-details/varicella-vaccine
    Chickenpox is an infection caused by the varicella virus, and it is highly contagious. […] Chickenpox infections can have severe complications. About 1 of every 1,000 children infected with varicella will develop severe pneumonia (infection of the lungs) or encephalitis (infection of the brain). […] The varicella vaccine is a live, „weakened” form of natural varicella virus. […] The vaccine virus was also grown in guinea pig fibroblast cells. […] The varicella vaccine is given to children between 12 and 15 months and again between 4 and 6 years of age. […] Since the introduction of the single-dose varicella vaccine into the United States in 1995, and the second-dose vaccine in 2006, the number of people infected with chickenpox has decreased by about 97%. […] The varicella vaccine does not have serious side effects. Therefore, the benefits of the varicella vaccine clearly outweigh its risks.
  • #39 Varicella (Chickenpox) Vaccine – Skin Center
    https://www.skincenter.com/patient-education/healthwise?DOCHWID=a607029
    Varicella vaccine can prevent varicella. […] Chickenpox is usually mild, but it can be serious in infants under 12 months of age, adolescents, adults, pregnant women, and people with a weakened immune system. […] Most people who are vaccinated with 2 doses of varicella vaccine will be protected for life. […] Some people who are vaccinated against chickenpox get shingles (herpes zoster) years later. This is much less common after vaccination than after chickenpox disease.
  • #40 Chickenpox: Causes, Symptoms, Treatment & Prevention
    https://my.clevelandclinic.org/health/diseases/4017-chickenpox
    Chickenpox is an infection that causes an itchy, blister-like skin rash. A virus called varicella-zoster causes it. Chickenpox is highly contagious. But its much less common today because theres a vaccine that protects you from it. […] Before the availability of the first vaccine against chickenpox in 1995, almost everyone got chickenpox as a toddler or young child. But since the late 1990s, the rate of chickenpox has declined by nearly 90%. Today, most children receive a vaccine against chickenpox as part of their routine immunization schedule. […] Chickenpox isn’t as common as it once was because the chickenpox vaccine has greatly reduced the number of cases. […] Yes, there’s a vaccine for chickenpox. Your child’s pediatrician will give it in two doses. […] Vaccination is over 90% effective at preventing chickenpox. Since 1995, the vaccine has prevented at least 91 million cases of chickenpox. […] The chickenpox vaccine is over 90% effective at preventing this once-common childhood illness.
  • #41 Chickenpox – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/chickenpox/symptoms-causes/syc-20351282
    Chickenpox is an illness caused by the varicella-zoster virus. […] A virus called varicella-zoster causes chickenpox. […] Your risk of getting infected with the virus that causes chickenpox is higher if you haven’t already had chickenpox or if you haven’t had the chickenpox vaccine. […] Most people who have had chickenpox or have gotten the vaccine are immune to chickenpox. […] The chickenpox vaccine is a safe way to prevent this illness and the other health problems that can happen during it. […] The chickenpox vaccine, also called the varicella vaccine, is the best way to prevent chickenpox. […] In the United States, experts from the CDC report that two doses of the vaccine prevent illness over 90% of the time. […] If you don’t remember whether you’ve had chickenpox or the vaccine, your provider can give you a blood test to find out.
  • #42 Varicella (chickenpox) vaccines: Canadian Immunization Guide – Canada.ca
    https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/page-24-varicella-chickenpox-vaccine.html
    Primary varicella zoster virus infection causes varicella (chickenpox) and reactivated infection results in herpes zoster (shingles). […] Complications are more common in adolescents, adults and immunocompromised individuals. Individuals with impaired immunity are at risk of severe varicella and death. […] Varicella-containing vaccine is available as univalent varicella vaccine or combined multivalent measles-mumps-rubella-varicella (MMRV) vaccine. […] The efficacy of varicella vaccines in children is estimated to be 94.4% following a single dose and 98.3% following a second dose. […] In countries without vaccination programs, varicella is mainly a disease of childhood, developing in 50% of children by the age of 5 years and 90% by the age of 12 years. […] Since the introduction of immunization programs in Canada, there has been a decrease in the burden of varicella.
  • #43 Chickenpox vaccine | Healthify
    https://healthify.nz/medicines-a-z/c/chickenpox-vaccine/
    Chickenpox vaccine protects against infection from the varicella zoster virus, which causes chickenpox infection. […] The chickenpox vaccine is a live vaccine which is made using chickenpox viruses that have been weakened (or attenuated), before being included in the vaccine. […] A single chickenpox vaccine dose provides about 99% protection against severe disease and 80% protection against chickenpox infection at all. […] Chickenpox vaccine is a live vaccine. This means that it can cause chickenpox, although it is usually milder, and it shouldn’t be used for certain groups of people who have reduced infection-fighting ability (immunity).
  • #44 Chicken pox vaccine | Childhood VaccinationsAccessibility ToolsIncrease TextDecrease TextGrayscaleHigh ContrastNegative ContrastLight BackgroundLinks UnderlineReadable FontReset
    https://www.gha.gi/public-health/childrens-health/childhood-vaccinations/chicken-pox-vaccine/
    The chickenpox vaccine protects against the varicella zoster virus that causes chickenpox. […] The vaccine, is however given as part of the routine vaccination schedule in some other countries, such as the US and Germany. […] The chickenpox vaccine is a live vaccine and contains a small amount of weakened chickenpox-causing virus. It stimulates your immune system to produce antibodies that will help protect against chickenpox. […] Studies show that 9 out of 10 children vaccinated with a single dose will develop immunity against chickenpox. Having 2 doses as recommended gives an even better immune response. […] People with weakened immune systems and pregnant women without immunity who are exposed to chickenpox can be given a medication called varicella zoster immunoglobulin (VZIG). VZIG contains chickenpox virus-fighting antibodies, and can reduce symptoms of chickenpox and lower the risk of complications for those exposed to the infection.
  • #45 Varicella (Chickenpox): The Disease & Vaccines | Children’s Hospital of Philadelphia
    https://www.chop.edu/vaccine-education-center/vaccine-details/varicella-vaccine
    Chickenpox is an infection caused by the varicella virus, and it is highly contagious. […] Chickenpox infections can have severe complications. About 1 of every 1,000 children infected with varicella will develop severe pneumonia (infection of the lungs) or encephalitis (infection of the brain). […] The varicella vaccine is a live, „weakened” form of natural varicella virus. […] The vaccine virus was also grown in guinea pig fibroblast cells. […] The varicella vaccine is given to children between 12 and 15 months and again between 4 and 6 years of age. […] Since the introduction of the single-dose varicella vaccine into the United States in 1995, and the second-dose vaccine in 2006, the number of people infected with chickenpox has decreased by about 97%. […] The varicella vaccine does not have serious side effects. Therefore, the benefits of the varicella vaccine clearly outweigh its risks.
  • #46
    https://www.healthychildren.org/English/health-issues/vaccine-preventable-diseases/Pages/Varicella-ChickenPox.aspx
    Chickenpox is a highly contagious disease caused by the varicella-zoster virus. […] Since the vaccine became available in 1995, infections have gone down 97%. […] The chickenpox vaccine is recommended for all children who have not had the disease. Most people who get the vaccine are protected for life and won’t get chickenpox. […] Children receive two doses of chickenpox vaccine to ensure the broadest protection. […] The chickenpox vaccine also lowers the risk of another painful rash, called shingles, later in life. The virus that causes chickenpox also causes shingles.
  • #47 Chapter 22: Varicella | Pink Book | CDC
    https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-22-varicella.html
    Varicella is an acute infectious disease caused by varicella-zoster virus (VZV). […] A live, attenuated varicella vaccine was developed in Japan in the 1970s. […] Varicella vaccine was licensed for general use in Japan and Korea in 1988, and in the United States in 1995 for persons age 12 months or older. […] Primary infection with VZV results in varicella. […] Breakthrough varicella is defined as varicella due to infection with wild-type VZV occurring more than 42 days after varicella vaccination; breakthrough infection can occur after 1 or 2 doses of vaccine. […] The risk of complications from varicella varies with age. […] Since 1995, when the varicella vaccination program was implemented, hospitalizations and deaths from varicella have declined in the United States 93% and 94%, respectively.
  • #48 Why don’t some countries vaccinate against chickenpox?
    https://www.bbc.com/future/article/20240229-why-dont-some-countries-vaccinate-against-chickenpox
    Overall, the US Centers for Disease Control and Prevention estimate that during the first 25 years of the chickenpox vaccination programme, the jab prevented an estimated 91 million cases, 238,000 hospitalisations, and 2,000 deaths. […] Some of the concerns have stemmed from the potential consequences of vaccine hesitancy, which was named as one of the top 10 threats to global health by the WHO in 2019. […] The biggest fear has been lingering concerns that chickenpox vaccination might increase the risk of shingles among unvaccinated individuals in later life. […] Essentially when we contract chickenpox as children, the virus’ DNA lingers deep in our nerve cells, giving it the capability of reactivating many decades later. […] One of the concerns has long been that if most children received a chickenpox vaccine, this boosting effect would be removed, possibly causing adult immunity to wane faster and leading to more shingles cases.
  • #49 History of Chickenpox and How the Vaccine Changed Everything 
    https://pedsondemand.com/pediatric-care/history-of-chickenpox-and-how-the-vaccine-changed-everything/
    Chickenpox is a virus infection and causes flu-like symptoms. […] The disease is caused by the varicella-zoster virus that belongs to the a-herpes virus family. […] It was not until the early 20th century that researchers began to connect the dots and discovered the relationship between the primary phase infection, chickenpox (varicella), and the resurfacing of the latent virus known as shingles (zoster). […] According to the CDC, more than 3.5 million cases of varicella and 9,000 hospitalizations are prevented each year thanks to the chickenpox vaccination. […] Once the vaccine was developed, there was a rapid and clear decline in the number of cases and hospitalizations. […] The data clearly show that with more children getting the vaccine, it has reduced significantly the number of cases that happen and are spread through school contact.
  • #50 Chapter 22: Varicella | Pink Book | CDC
    https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-22-varicella.html
    Varicella is an acute infectious disease caused by varicella-zoster virus (VZV). […] A live, attenuated varicella vaccine was developed in Japan in the 1970s. […] Varicella vaccine was licensed for general use in Japan and Korea in 1988, and in the United States in 1995 for persons age 12 months or older. […] Primary infection with VZV results in varicella. […] Breakthrough varicella is defined as varicella due to infection with wild-type VZV occurring more than 42 days after varicella vaccination; breakthrough infection can occur after 1 or 2 doses of vaccine. […] The risk of complications from varicella varies with age. […] Since 1995, when the varicella vaccination program was implemented, hospitalizations and deaths from varicella have declined in the United States 93% and 94%, respectively.
  • #51 Chickenpox (Varicella) Vaccine: Schedule and Side Effects
    https://www.webmd.com/children/vaccines/chickenpox-varicella-vaccine
    The chickenpox vaccine is a shot that can protect nearly anyone who receives the vaccine from catching chickenpox. It’s also called the varicella vaccine because chickenpox is caused by the varicella-zoster virus. The vaccine is made from a live but weakened, or attenuated, virus. […] Although the virus in the chickenpox vaccine is generally incapable of causing a disease, it still stimulates a response from the body’s immune system. That response is what gives someone who’s had a shot for chickenpox immunity or protection from the illness. […] About 2% of the children who are vaccinated develop a very mild case of chickenpox, usually with no more than five to six blisters. It is also possible for a person who has been vaccinated for chickenpox to develop chickenpox at some later point in life. When that happens, the disease is almost always milder and the recovery more rapid than for people who have not had the shots.
  • #52 Why did I get chickenpox even though I’ve been vaccinated?
    https://www.drugs.com/medical-answers/chickenpox-vaccinated-3573682/
    Previous vaccination with the varicella vaccine does not always guarantee that a person will not develop chickenpox symptoms. However, if they do, these symptoms are usually much milder than in an unvaccinated person. […] The effectiveness of vaccination depends upon how many doses of the vaccine have been given, and how strong the person’s immune system is. […] Chickenpox that occurs in a person who has been previously vaccinated against the disease is called “breakthrough varicella”, and it is usually mild. […] Vaccination is generally long-lasting although experts aren’t sure exactly how long it lasts.
  • #53 Varicella (Chickenpox) Vaccine – Skin Center
    https://www.skincenter.com/patient-education/healthwise?DOCHWID=a607029
    Varicella vaccine can prevent varicella. […] Chickenpox is usually mild, but it can be serious in infants under 12 months of age, adolescents, adults, pregnant women, and people with a weakened immune system. […] Most people who are vaccinated with 2 doses of varicella vaccine will be protected for life. […] Some people who are vaccinated against chickenpox get shingles (herpes zoster) years later. This is much less common after vaccination than after chickenpox disease.
  • #54 Varicella (Chickenpox) Vaccine: What You Need to Know | Kaiser Permanente
    https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.varicella-chickenpox-vaccine-what-you-need-to-know.cdc19
    Varicella vaccine can prevent varicella. […] Varicella, also called „chickenpox,” causes an itchy rash that usually lasts about a week. […] Chickenpox is usually mild, but it can be serious in infants under 12 months of age, adolescents, adults, pregnant people, and people with a weakened immune system. […] Most people who are vaccinated with 2 doses of varicella vaccine will be protected for life. […] Some people who are vaccinated against chickenpox get shingles (herpes zoster) years later. This is much less common after vaccination than after chickenpox disease. […] In people with serious immune system problems, this vaccine may cause an infection that may be life-threatening. People with serious immune system problems should not get varicella vaccine.
  • #55 Clinical Overview of Chickenpox (Varicella) | Chickenpox (Varicella) | CDC
    https://www.cdc.gov/chickenpox/hcp/clinical-overview/index.html
    Varicella (chickenpox) is an acute infectious disease caused by varicella-zoster virus (VZV). […] Varicella is highly caused by varicella-zoster virus (VZV), which is a DNA virus that is a member of the herpesvirus group. Primary infection with VZV causes varicella. […] The most effective prevention for varicella is chickenpox vaccination. […] The varicella vaccination program has dramatically decreased virus circulation and increased community protection. […] The risk of shingles is significantly lower among vaccinated children, including those who are immunocompromised. […] Chickenpox is a highly contagious disease caused by the varicella-zoster virus (VZV).
  • #56 Why don’t some countries vaccinate against chickenpox?
    https://www.bbc.com/future/article/20240229-why-dont-some-countries-vaccinate-against-chickenpox
    Overall, the US Centers for Disease Control and Prevention estimate that during the first 25 years of the chickenpox vaccination programme, the jab prevented an estimated 91 million cases, 238,000 hospitalisations, and 2,000 deaths. […] Some of the concerns have stemmed from the potential consequences of vaccine hesitancy, which was named as one of the top 10 threats to global health by the WHO in 2019. […] The biggest fear has been lingering concerns that chickenpox vaccination might increase the risk of shingles among unvaccinated individuals in later life. […] Essentially when we contract chickenpox as children, the virus’ DNA lingers deep in our nerve cells, giving it the capability of reactivating many decades later. […] One of the concerns has long been that if most children received a chickenpox vaccine, this boosting effect would be removed, possibly causing adult immunity to wane faster and leading to more shingles cases.
  • #57 Chickenpox vaccination does increase shingles cases, but mainly in young adults | ScienceDaily
    https://www.sciencedaily.com/releases/2015/08/150811103555.htm
    Vaccinating one-year-olds against chickenpox could temporarily nearly double the incidence of shingles in the wider population, but in younger adults than previously thought. […] The effect occurs because vaccination reduces the likelihood of adults who experienced chickenpox as a child being re-exposed to the virus. Re-exposure boosts immunity to shingles, caused by the same virus, Varicella-zoster virus. […] „We were surprised to find that re-exposure to chickenpox is beneficial for so few years and also that the most pronounced effect of vaccination on increasing cases of shingles is in younger adults,” says lead author Dr Benson Ogunjimi. […] Shingles occurs most often in individuals with a declined immunological status, such as HIV or cancer patients. Aging is also assumed to increase susceptibility.
  • #58 Why don’t some countries vaccinate against chickenpox?
    https://www.bbc.com/future/article/20240229-why-dont-some-countries-vaccinate-against-chickenpox
    In the last five years, opinions has begun to shift following large-scale epidemiological studies which have shown that the US and other countries have not actually seen the feared increase in shingles cases over the last three decades. […] The improved certainty about this has really made the cost-effectiveness modelling more robust.
  • #59 Chickenpox vaccination does increase shingles cases, but mainly in young adults | ScienceDaily
    https://www.sciencedaily.com/releases/2015/08/150811103555.htm
    Vaccinating one-year-olds against chickenpox could temporarily nearly double the incidence of shingles in the wider population, but in younger adults than previously thought. […] The effect occurs because vaccination reduces the likelihood of adults who experienced chickenpox as a child being re-exposed to the virus. Re-exposure boosts immunity to shingles, caused by the same virus, Varicella-zoster virus. […] „We were surprised to find that re-exposure to chickenpox is beneficial for so few years and also that the most pronounced effect of vaccination on increasing cases of shingles is in younger adults,” says lead author Dr Benson Ogunjimi. […] Shingles occurs most often in individuals with a declined immunological status, such as HIV or cancer patients. Aging is also assumed to increase susceptibility.
  • #60 Two-for-One: Chickenpox Vaccine Lowers Shingles Risk in Children | Scientific American
    https://www.scientificamerican.com/article/two-for-one-chickenpox-vaccine-lowers-shingles-risk-in-children/
    Health organizations recommend children receive the varicella vaccine at one year old to protect them against chickenpox, but the vaccine appears to have another benefit: it cuts the risk of shingles, a painful and potentially debilitating rash caused by the reactivated chickenpox virus, by more than half in children over two years old, according to a new study. […] The chickenpox vaccine is made with the live attenuated (weakened) varicella virus, so not surprisingly, it can also become latent after vaccination, explains Anne A. Gershon, a professor of pediatric infectious disease at Columbia University. […] This study makes it clearer than ever before that the benefits of the varicella vaccine go beyond simply preventing chickenpox, says Nathan Boonstra, a general pediatrician at Blank Childrens Hospital in Des Moines, Iowa, who cohosts the podcast Vax Talk and was not involved in the study.
  • #61
    https://www.healthychildren.org/English/health-issues/vaccine-preventable-diseases/Pages/Varicella-ChickenPox.aspx
    Chickenpox is a highly contagious disease caused by the varicella-zoster virus. […] Since the vaccine became available in 1995, infections have gone down 97%. […] The chickenpox vaccine is recommended for all children who have not had the disease. Most people who get the vaccine are protected for life and won’t get chickenpox. […] Children receive two doses of chickenpox vaccine to ensure the broadest protection. […] The chickenpox vaccine also lowers the risk of another painful rash, called shingles, later in life. The virus that causes chickenpox also causes shingles.
  • #62 Chapter 22: Varicella | Pink Book | CDC
    https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-22-varicella.html
    Varicella vaccine is recommended for use in persons age 12 months or older without evidence of varicella immunity within 3 through 5 days after exposure to varicella. […] Data from the United States and Japan in a variety of settings indicate that varicella vaccine is 70% to 100% effective in preventing illness or modifying the severity of illness if used within 3 days, and possibly up to 5 days, after exposure. […] The interval until immune reconstruction varies with the intensity and type of immunosuppressive therapy, radiation therapy, underlying disease, and other factors, complicating the ability to make a definitive recommendation for an interval after cessation of immunosuppressive therapy when live-virus vaccines can be administered safely and effectively.
  • #63 Varicella (Chickenpox) Vaccine – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK441946/
    Varicella or chickenpox is a common and highly contagious exanthematic disease caused by the varicella-zoster virus that, during primary infection, can establish latency. […] The varicella-zoster virus is a vaccine-preventable disease, and the FDA approves the live varicella virus vaccine to provide immunity for preventing varicella in individuals 12 months and older. […] Current vaccines against varicella and herpes zoster are not 100% efficacious; it is between 70% and 90% effective at preventing varicella and over 95% effective at preventing severe varicella. […] The varicella-zoster vaccine contains live attenuated varicella-zoster vaccine (Oka strain). This vaccine induces both humoral and cell-mediated immune responses. […] The varicella vaccine is contraindicated in individuals who have a severe allergy or have had an anaphylactic reaction to neomycin or gelatin, which are components of this vaccine, or to the previous dose of a varicella-containing vaccine. […] Maternal varicella infection has been shown to harm the fetus, but the vaccination effects have not been tested on pregnant women, and the effects on fetal development are currently unknown.
  • #64 Varicella (chickenpox) vaccines: Canadian Immunization Guide – Canada.ca
    https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/page-24-varicella-chickenpox-vaccine.html
    Varicella (chickenpox) is a generalized viral disease caused by varicella zoster virus (VZV), a deoxyribonucleic acid (DNA virus) of the Herpesvirus family. […] VZV is spread by the airborne route, as well as by direct contact with virus shed from skin lesions. […] The risk of varicella infection severity increases with age. […] The following groups of individuals are considered to be at increased risk of severe varicella: Newborn infants of mothers who develop varicella from 5 days before until 48 hours after delivery; Neonates in intensive care settings born at less than 28 weeks of gestation or weighing 1,000 g or less at birth, regardless of their mothers’ evidence of immunity; Susceptible pregnant women; Susceptible immunocompromised persons, including HIV-infected persons with CD4 cell count 200 106/L or CD4 percentage 15%. […] Varicella vaccine is recommended for susceptible individuals with chronic renal disease or undergoing dialysis. […] Individuals who are immunocompromised, either due to underlying conditions or immunosuppressive agents, are more susceptible to infections including varicella.
  • #65 Varicella (Chickenpox): The Disease & Vaccines | Children’s Hospital of Philadelphia
    https://www.chop.edu/vaccine-education-center/vaccine-details/varicella-vaccine
    Chickenpox is an infection caused by the varicella virus, and it is highly contagious. […] Chickenpox infections can have severe complications. About 1 of every 1,000 children infected with varicella will develop severe pneumonia (infection of the lungs) or encephalitis (infection of the brain). […] The varicella vaccine is a live, „weakened” form of natural varicella virus. […] The vaccine virus was also grown in guinea pig fibroblast cells. […] The varicella vaccine is given to children between 12 and 15 months and again between 4 and 6 years of age. […] Since the introduction of the single-dose varicella vaccine into the United States in 1995, and the second-dose vaccine in 2006, the number of people infected with chickenpox has decreased by about 97%. […] The varicella vaccine does not have serious side effects. Therefore, the benefits of the varicella vaccine clearly outweigh its risks.
  • #66 Chickenpox Causes and Treatment | Lurie Children’s
    https://www.luriechildrens.org/en/blog/chickenpox-causes-and-treatment/
    The varicella-zoster virus (VZV) causes chickenpox. Exposure to this virus is the only way to get the illness. Humans are the only source of infection for this highly contagious virus, Dr. Tan says. […] The best way to prevent chickenpox is to get vaccinated. Doctors give the varicella (chickenpox) vaccine in two doses. Children should get the vaccine: At 12 to 15 months old (first dose) At 4 to 6 years old (second dose). […] Adolescents, adults and older children who havent had chickenpox and are not vaccinated should also get the vaccine. Vaccinated people can still get chickenpox, but usually, symptoms will be mild.
  • #67 Varicella (chickenpox) | The Australian Immunisation Handbook
    https://immunisationhandbook.health.gov.au/contents/vaccine-preventable-diseases/varicella-chickenpox
    Varicella is a highly contagious infection caused by varicella-zoster virus. Primary infection with varicella-zoster virus causes varicella (chickenpox). […] Varicella-containing vaccine is recommended for all non-immune adolescents aged ≥14 years and adults. […] Varicella vaccine is recommended for household contacts of people who are immunocompromised. […] Transmission of the varicella vaccine virus strain is extremely rare and is likely to cause only mild disease in the person who is immunocompromised. […] Previous varicella infection is not a contraindication to varicella vaccination. Children who have had varicella infection can receive varicella-containing vaccines. […] Varicella is more severe in adults, particularly in pregnant women and people who are immunocompromised.
  • #68 Chickenpox Causes and Treatment | Lurie Children’s
    https://www.luriechildrens.org/en/blog/chickenpox-causes-and-treatment/
    The varicella-zoster virus (VZV) causes chickenpox. Exposure to this virus is the only way to get the illness. Humans are the only source of infection for this highly contagious virus, Dr. Tan says. […] The best way to prevent chickenpox is to get vaccinated. Doctors give the varicella (chickenpox) vaccine in two doses. Children should get the vaccine: At 12 to 15 months old (first dose) At 4 to 6 years old (second dose). […] Adolescents, adults and older children who havent had chickenpox and are not vaccinated should also get the vaccine. Vaccinated people can still get chickenpox, but usually, symptoms will be mild.
  • #69 Varicella (chickenpox) | The Australian Immunisation Handbook
    https://immunisationhandbook.health.gov.au/contents/vaccine-preventable-diseases/varicella-chickenpox
    Varicella is a highly contagious infection caused by varicella-zoster virus. Primary infection with varicella-zoster virus causes varicella (chickenpox). […] Varicella-containing vaccine is recommended for all non-immune adolescents aged ≥14 years and adults. […] Varicella vaccine is recommended for household contacts of people who are immunocompromised. […] Transmission of the varicella vaccine virus strain is extremely rare and is likely to cause only mild disease in the person who is immunocompromised. […] Previous varicella infection is not a contraindication to varicella vaccination. Children who have had varicella infection can receive varicella-containing vaccines. […] Varicella is more severe in adults, particularly in pregnant women and people who are immunocompromised.
  • #70 Chickenpox (varicella) – symptoms, treatment, vaccine | healthdirect
    https://www.healthdirect.gov.au/chickenpox
    Chickenpox is a very contagious infection caused by the varicella zoster virus. […] Vaccination is the best way to protect yourself against chickenpox. […] The best way to prevent chickenpox is through vaccination. […] Most vaccinated people will not get chickenpox. If you do get infected you will generally have a milder form of chickenpox and a quicker recovery. […] The chickenpox vaccine is not recommended when you are pregnant or if you have a weakened immune system. […] The chickenpox vaccine is not advised during pregnancy, so its better to get the vaccine before you get pregnant. […] Vaccination against chickenpox is strongly recommended if you work in childcare, aged care, or healthcare.
  • #71 Varicella (chickenpox) vaccines: Canadian Immunization Guide – Canada.ca
    https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/page-24-varicella-chickenpox-vaccine.html
    Varicella (chickenpox) is a generalized viral disease caused by varicella zoster virus (VZV), a deoxyribonucleic acid (DNA virus) of the Herpesvirus family. […] VZV is spread by the airborne route, as well as by direct contact with virus shed from skin lesions. […] The risk of varicella infection severity increases with age. […] The following groups of individuals are considered to be at increased risk of severe varicella: Newborn infants of mothers who develop varicella from 5 days before until 48 hours after delivery; Neonates in intensive care settings born at less than 28 weeks of gestation or weighing 1,000 g or less at birth, regardless of their mothers’ evidence of immunity; Susceptible pregnant women; Susceptible immunocompromised persons, including HIV-infected persons with CD4 cell count 200 106/L or CD4 percentage 15%. […] Varicella vaccine is recommended for susceptible individuals with chronic renal disease or undergoing dialysis. […] Individuals who are immunocompromised, either due to underlying conditions or immunosuppressive agents, are more susceptible to infections including varicella.
  • #72 Varicella (Chickenpox) Vaccine – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK441946/
    Varicella or chickenpox is a common and highly contagious exanthematic disease caused by the varicella-zoster virus that, during primary infection, can establish latency. […] The varicella-zoster virus is a vaccine-preventable disease, and the FDA approves the live varicella virus vaccine to provide immunity for preventing varicella in individuals 12 months and older. […] Current vaccines against varicella and herpes zoster are not 100% efficacious; it is between 70% and 90% effective at preventing varicella and over 95% effective at preventing severe varicella. […] The varicella-zoster vaccine contains live attenuated varicella-zoster vaccine (Oka strain). This vaccine induces both humoral and cell-mediated immune responses. […] The varicella vaccine is contraindicated in individuals who have a severe allergy or have had an anaphylactic reaction to neomycin or gelatin, which are components of this vaccine, or to the previous dose of a varicella-containing vaccine. […] Maternal varicella infection has been shown to harm the fetus, but the vaccination effects have not been tested on pregnant women, and the effects on fetal development are currently unknown.
  • #73 Chickenpox | Mass.gov
    https://www.mass.gov/info-details/chickenpox
    Chickenpox, also called varicella, is a disease caused by a virus that spreads easily from person to person. […] Two doses of chickenpox vaccine are recommended to protect against disease. […] Pregnant women who have already had chickenpox disease or the vaccine do not need to worry. […] Yes, it is safe for most people. […] People who have serious allergies to gelatin, the drug neomycin, or a previous dose of the vaccine should not get the vaccine.
  • #74 Varicella (Chickenpox) Vaccine: What You Need to Know | Kaiser Permanente
    https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.varicella-chickenpox-vaccine-what-you-need-to-know.cdc19
    Varicella vaccine can prevent varicella. […] Varicella, also called „chickenpox,” causes an itchy rash that usually lasts about a week. […] Chickenpox is usually mild, but it can be serious in infants under 12 months of age, adolescents, adults, pregnant people, and people with a weakened immune system. […] Most people who are vaccinated with 2 doses of varicella vaccine will be protected for life. […] Some people who are vaccinated against chickenpox get shingles (herpes zoster) years later. This is much less common after vaccination than after chickenpox disease. […] In people with serious immune system problems, this vaccine may cause an infection that may be life-threatening. People with serious immune system problems should not get varicella vaccine.
  • #75 Varicella (Chickenpox) Vaccine: What You Need to Know – The Medical Group of New Jersey | Sussex Cardiology
    https://sussexheart.com/health-library/healthwise?DOCHWID=cdc19
    Varicella vaccine can prevent varicella. […] Varicella, also called „chickenpox,” causes an itchy rash that usually lasts about a week. It can also cause fever, tiredness, loss of appetite, and headache. It can lead to skin infections, pneumonia, inflammation of the blood vessels, swelling of the brain and/or spinal cord covering, and infections of the bloodstream, bone, or joints. Some people who get chickenpox get a painful rash called „shingles” (also known as herpes zoster) years later. […] Most people who are vaccinated with 2 doses of varicella vaccine will be protected for life. […] Older children, adolescents, and adults also need 2 doses of varicella vaccine if they are not already immune to chickenpox. […] Varicella vaccine may be given at the same time as other vaccines. […] In people with serious immune system problems, this vaccine may cause an infection that may be life-threatening. […] Some people who are vaccinated against chickenpox get shingles (herpes zoster) years later. This is much less common after vaccination than after chickenpox disease.
  • #76 Chickenpox (varicella) – symptoms, treatment, vaccine | healthdirect
    https://www.healthdirect.gov.au/chickenpox
    Chickenpox is a very contagious infection caused by the varicella zoster virus. […] Vaccination is the best way to protect yourself against chickenpox. […] The best way to prevent chickenpox is through vaccination. […] Most vaccinated people will not get chickenpox. If you do get infected you will generally have a milder form of chickenpox and a quicker recovery. […] The chickenpox vaccine is not recommended when you are pregnant or if you have a weakened immune system. […] The chickenpox vaccine is not advised during pregnancy, so its better to get the vaccine before you get pregnant. […] Vaccination against chickenpox is strongly recommended if you work in childcare, aged care, or healthcare.
  • #77 Chickenpox in adults: Symptoms, treatments, and vaccination
    https://www.medicalnewstoday.com/articles/326178
    Although chickenpox commonly occurs in childhood, adults can also get chickenpox. The chickenpox vaccine has helped reduce the number of people who get the virus each year, but chickenpox can still develop in people of all ages. […] Chickenpox rates have reduced among all age groups because of the chickenpox vaccine. […] Adults can receive a chickenpox vaccine if they have never had chickenpox or if they were not vaccinated as children. […] Doctors do not usually recommend that pregnant women get the chickenpox vaccine. This is because the vaccine contains live viruses that can affect pregnancy. […] If a pregnant woman has a high risk of chickenpox but has never gotten it, the doctor may inject a medication that can help protect her immune system against chickenpox. […] Also, a person can get the chickenpox vaccine if they have never had chickenpox but were recently exposed to it. The CDC recommend vaccination 3-5 days after exposure to chickenpox.
  • #78 Varicella (Chickenpox) Vaccine – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK441946/
    Varicella or chickenpox is a common and highly contagious exanthematic disease caused by the varicella-zoster virus that, during primary infection, can establish latency. […] The varicella-zoster virus is a vaccine-preventable disease, and the FDA approves the live varicella virus vaccine to provide immunity for preventing varicella in individuals 12 months and older. […] Current vaccines against varicella and herpes zoster are not 100% efficacious; it is between 70% and 90% effective at preventing varicella and over 95% effective at preventing severe varicella. […] The varicella-zoster vaccine contains live attenuated varicella-zoster vaccine (Oka strain). This vaccine induces both humoral and cell-mediated immune responses. […] The varicella vaccine is contraindicated in individuals who have a severe allergy or have had an anaphylactic reaction to neomycin or gelatin, which are components of this vaccine, or to the previous dose of a varicella-containing vaccine. […] Maternal varicella infection has been shown to harm the fetus, but the vaccination effects have not been tested on pregnant women, and the effects on fetal development are currently unknown.
  • #79 Chickenpox Vaccine Side Effects – National Vaccine Support Group
    https://immunizationinfo.com/chickenpox-varivax-vaccine-side-effects/
    No one knows if the chickenpox vaccine causes birth defects, but pregnant women should NOT get vaccinated because wild-type varicella (natural chickenpox infections) are known to cause birth defects. Do not get pregnant for 3 months after receiving the vaccine. […] Varivax contains a live varicella (chickenpox) virus that is “attenuated,” meaning it has been weakened, but it still causes a mild infection. The virus came from a child who was infected with a wild-type Oka strain.
  • #80 Chapter 22: Varicella | Pink Book | CDC
    https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-22-varicella.html
    Varicella vaccine is recommended for use in persons age 12 months or older without evidence of varicella immunity within 3 through 5 days after exposure to varicella. […] Data from the United States and Japan in a variety of settings indicate that varicella vaccine is 70% to 100% effective in preventing illness or modifying the severity of illness if used within 3 days, and possibly up to 5 days, after exposure. […] The interval until immune reconstruction varies with the intensity and type of immunosuppressive therapy, radiation therapy, underlying disease, and other factors, complicating the ability to make a definitive recommendation for an interval after cessation of immunosuppressive therapy when live-virus vaccines can be administered safely and effectively.
  • #81 Chickenpox vaccination – Superdrug Health Clinic
    https://healthclinics.superdrug.com/services/chickenpox-vaccination/
    Chickenpox is a very common illness caused by the varicella-zoster virus. The chickenpox vaccine offers effective protection for patients who have not had chickenpox before. […] The chickenpox vaccine is not currently part of the national vaccine schedule in the UK but it has been given routinely in a number of countries around the world, such as the USA and Germany. […] The chickenpox vaccine offers effective protection against chickenpox. […] It belongs to a group of vaccines referred to as “live” vaccines. This means, that it contains a weakened version of the virus that causes chickenpox. The vaccine causes your immune system to react to the vaccine. As a result, you’ll be immune to it if you catch the virus at a later date. […] If you have been exposed to the chickenpox virus the vaccine will still prevent it if you get vaccinated within three days of exposure.
  • #82 Chapter 22: Varicella | Pink Book | CDC
    https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-22-varicella.html
    Varicella vaccine is recommended for use in persons age 12 months or older without evidence of varicella immunity within 3 through 5 days after exposure to varicella. […] Data from the United States and Japan in a variety of settings indicate that varicella vaccine is 70% to 100% effective in preventing illness or modifying the severity of illness if used within 3 days, and possibly up to 5 days, after exposure. […] The interval until immune reconstruction varies with the intensity and type of immunosuppressive therapy, radiation therapy, underlying disease, and other factors, complicating the ability to make a definitive recommendation for an interval after cessation of immunosuppressive therapy when live-virus vaccines can be administered safely and effectively.
  • #83 Your Child’s Vaccines: Chickenpox Vaccine (for Parents) | Nemours KidsHealth
    https://kidshealth.org/en/parents/varicella-vaccine.html
    The varicella vaccine protects against chickenpox (varicella), a common and very contagious childhood viral illness. It also protects against shingles. It is a live attenuated vaccine, which means it contains a weakened form of the virus. […] Chickenpox used to be common in the U.S., causing many hospitalizations and even deaths. Since the vaccine was introduced in 1995, it has prevented millions of infections every year. It prevents severe illness in almost all kids who are vaccinated. It’s also very effective in preventing mild illness. Vaccinated kids who do get chickenpox generally have a mild case. […] If a person with no immunity to the virus is exposed to someone with chickenpox or shingles, they are likely to get infected because the virus is so contagious. Giving the vaccine within 3 to 5 days after exposure can help to prevent the infection or make it less serious.
  • #84 Varicella-Zoster Virus (Chickenpox and Shingles) & Communicable Diseases | Health & Senior Services
    https://health.mo.gov/living/healthcondiseases/communicable/chickenpox.php
    Varicella-zoster is a herpes virus that causes chickenpox, a common childhood illness. It is highly contagious. […] Chickenpox first occurs as a blister-like skin rash and fever. […] Yes. About 15% 20% of people who have received one dose of varicella (chickenpox) vaccine do still get chickenpox if they are exposed, but their disease is usually mild. […] Serious problems can occur and may include pneumonia (bacterial and viral), brain infection (encephalitis), and kidney problems. […] Because of these risks, pregnant women without evidence of immunity to varicella who have been exposed to the virus may be given varicella-zoster immune globulin (VZIG) to reduce their risk of disease complications. […] Vaccination is the best way to protect yourself and those you love. If you are not immune, you should be vaccinated.
  • #85 Chicken pox vaccine | Childhood VaccinationsAccessibility ToolsIncrease TextDecrease TextGrayscaleHigh ContrastNegative ContrastLight BackgroundLinks UnderlineReadable FontReset
    https://www.gha.gi/public-health/childrens-health/childhood-vaccinations/chicken-pox-vaccine/
    The chickenpox vaccine protects against the varicella zoster virus that causes chickenpox. […] The vaccine, is however given as part of the routine vaccination schedule in some other countries, such as the US and Germany. […] The chickenpox vaccine is a live vaccine and contains a small amount of weakened chickenpox-causing virus. It stimulates your immune system to produce antibodies that will help protect against chickenpox. […] Studies show that 9 out of 10 children vaccinated with a single dose will develop immunity against chickenpox. Having 2 doses as recommended gives an even better immune response. […] People with weakened immune systems and pregnant women without immunity who are exposed to chickenpox can be given a medication called varicella zoster immunoglobulin (VZIG). VZIG contains chickenpox virus-fighting antibodies, and can reduce symptoms of chickenpox and lower the risk of complications for those exposed to the infection.
  • #86 Chicken pox vaccine | Childhood VaccinationsAccessibility ToolsIncrease TextDecrease TextGrayscaleHigh ContrastNegative ContrastLight BackgroundLinks UnderlineReadable FontReset
    https://www.gha.gi/public-health/childrens-health/childhood-vaccinations/chicken-pox-vaccine/
    The chickenpox vaccine protects against the varicella zoster virus that causes chickenpox. […] The vaccine, is however given as part of the routine vaccination schedule in some other countries, such as the US and Germany. […] The chickenpox vaccine is a live vaccine and contains a small amount of weakened chickenpox-causing virus. It stimulates your immune system to produce antibodies that will help protect against chickenpox. […] Studies show that 9 out of 10 children vaccinated with a single dose will develop immunity against chickenpox. Having 2 doses as recommended gives an even better immune response. […] People with weakened immune systems and pregnant women without immunity who are exposed to chickenpox can be given a medication called varicella zoster immunoglobulin (VZIG). VZIG contains chickenpox virus-fighting antibodies, and can reduce symptoms of chickenpox and lower the risk of complications for those exposed to the infection.
  • #87 Chickenpox (varicella zoster infection)
    https://www.health.ny.gov/diseases/communicable/chickenpox/fact_sheet.htm
    Chickenpox is a highly contagious illness caused by the varicella-zoster virus (VZV), a type of herpes virus. […] Before the availability of the varicella vaccine in the U.S., almost everyone developed chickenpox. […] A vaccine to protect children against chickenpox was first licensed in 1995. […] Children who have never had chickenpox should routinely be administered two doses of varicella vaccine with the first dose at 12 to 15 months and the second dose at four to six years of age. […] Varicella vaccination is recommended for outbreak control. […] In 2006, a new product called VariZIG became available to protect patients without evidence of immunity to varicella who are at high risk for severe disease and complications and have been exposed to chickenpox.
  • #88 Varicella (Chickenpox): The Disease & Vaccines | Children’s Hospital of Philadelphia
    https://www.chop.edu/vaccine-education-center/vaccine-details/varicella-vaccine
    Chickenpox is an infection caused by the varicella virus, and it is highly contagious. […] Chickenpox infections can have severe complications. About 1 of every 1,000 children infected with varicella will develop severe pneumonia (infection of the lungs) or encephalitis (infection of the brain). […] The varicella vaccine is a live, „weakened” form of natural varicella virus. […] The vaccine virus was also grown in guinea pig fibroblast cells. […] The varicella vaccine is given to children between 12 and 15 months and again between 4 and 6 years of age. […] Since the introduction of the single-dose varicella vaccine into the United States in 1995, and the second-dose vaccine in 2006, the number of people infected with chickenpox has decreased by about 97%. […] The varicella vaccine does not have serious side effects. Therefore, the benefits of the varicella vaccine clearly outweigh its risks.
  • #89 Information about Chickenpox | Voices For Vaccines
    https://www.voicesforvaccines.org/vaccine-information/chickenpox/
    Chickenpox is a very contagious disease caused by the varicella zoster virus. […] Chickenpox can also cause fever, tiredness, loss of appetite, and headache. […] If a person gets chickenpox during the first half of pregnancy, the varicella virus can cause severe birth defects. […] The chickenpox vaccine needs 2 doses for the best protection. […] No vaccine is a 100% guarantee that a person will not get the disease, but it is unlikely a fully vaccinated person will get chickenpox. […] Mild vaccine reactions are normal and signs the body and vaccines are working together to create an immune response to protect against chickenpox. […] The vaccine is ALWAYS safer than the disease.
  • #90 Chickenpox Vaccine Side Effects – National Vaccine Support Group
    https://immunizationinfo.com/chickenpox-varivax-vaccine-side-effects/
    The chickenpox (varicella) vaccine often causes fevers and a mild chickenpox rash. Very rarely, vaccines against chickenpox can cause serious side effects like seizures or brain reactions. Children who are vaccinated can also develop shingles as adults. […] Serious side effects of the chickenpox vaccine are extremely rare. The reported injuries include severe allergic reactions, skin rashes, lung or liver infections, meningitis (brain inflammation), seizures, pneumonia, chickenpox infections from the virus in the vaccine, and more. […] Yes. The chickenpox vaccine contains a live virus. Once you get vaccinated, the virus stays in your body forever. In about 33% of adults, the virus re-activates and causes a devastating skin rash called shingles. […] Yes. About 7% of people get a mild chickenpox rash with a few bumps after receiving the vaccine. This rash is contagious, so you should avoid contact with non-immunized people for 6 weeks. In very rare cases, the chickenpox vaccine causes serious infections.
  • #91 Chickenpox Vaccine Side Effects – National Vaccine Support Group
    https://immunizationinfo.com/chickenpox-varivax-vaccine-side-effects/
    The chickenpox (varicella) vaccine often causes fevers and a mild chickenpox rash. Very rarely, vaccines against chickenpox can cause serious side effects like seizures or brain reactions. Children who are vaccinated can also develop shingles as adults. […] Serious side effects of the chickenpox vaccine are extremely rare. The reported injuries include severe allergic reactions, skin rashes, lung or liver infections, meningitis (brain inflammation), seizures, pneumonia, chickenpox infections from the virus in the vaccine, and more. […] Yes. The chickenpox vaccine contains a live virus. Once you get vaccinated, the virus stays in your body forever. In about 33% of adults, the virus re-activates and causes a devastating skin rash called shingles. […] Yes. About 7% of people get a mild chickenpox rash with a few bumps after receiving the vaccine. This rash is contagious, so you should avoid contact with non-immunized people for 6 weeks. In very rare cases, the chickenpox vaccine causes serious infections.
  • #92 Chickenpox (Varicella) Vaccine: Schedule and Side Effects
    https://www.webmd.com/children/vaccines/chickenpox-varicella-vaccine
    The chickenpox vaccine is a shot that can protect nearly anyone who receives the vaccine from catching chickenpox. It’s also called the varicella vaccine because chickenpox is caused by the varicella-zoster virus. The vaccine is made from a live but weakened, or attenuated, virus. […] Although the virus in the chickenpox vaccine is generally incapable of causing a disease, it still stimulates a response from the body’s immune system. That response is what gives someone who’s had a shot for chickenpox immunity or protection from the illness. […] About 2% of the children who are vaccinated develop a very mild case of chickenpox, usually with no more than five to six blisters. It is also possible for a person who has been vaccinated for chickenpox to develop chickenpox at some later point in life. When that happens, the disease is almost always milder and the recovery more rapid than for people who have not had the shots.
  • #93 Chickenpox Vaccine Side Effects & Reactions: Legal Help
    https://www.myvaccinelawyer.com/vaccine-injury-lawyer/resources/vaccine/chickenpox
    Chickenpox is an infection caused by the varicella-zoster virus. […] While there is no question that varicella vaccines are very effective at preventing chickenpox, unfortunately, many healthy children who get vaccinated also suffer dangerous chickenpox vaccine side effects. […] In some cases, complications from chickenpox vaccinations can lead to life-threatening illnesses and injuries. […] According to the CDC, getting the chickenpox vaccine is safer than getting chickenpox. Unfortunately, while this may be true for most people, many people suffer dangerous side effects after receiving the vaccine. […] Serious complications such as febrile seizures are also more common among ProQuad recipients and typically occur within five to twelve days after the first dose. […] Occasionally, recipients develop an autoimmune reaction causing Guillain-Barr syndrome, transverse myelitis or other serious injuries. […] An improperly administered vaccination may cause a serious side effect or shoulder injuries.
  • #94 Chickenpox Vaccine Side Effects & Reactions: Legal Help
    https://www.myvaccinelawyer.com/vaccine-injury-lawyer/resources/vaccine/chickenpox
    Chickenpox is an infection caused by the varicella-zoster virus. […] While there is no question that varicella vaccines are very effective at preventing chickenpox, unfortunately, many healthy children who get vaccinated also suffer dangerous chickenpox vaccine side effects. […] In some cases, complications from chickenpox vaccinations can lead to life-threatening illnesses and injuries. […] According to the CDC, getting the chickenpox vaccine is safer than getting chickenpox. Unfortunately, while this may be true for most people, many people suffer dangerous side effects after receiving the vaccine. […] Serious complications such as febrile seizures are also more common among ProQuad recipients and typically occur within five to twelve days after the first dose. […] Occasionally, recipients develop an autoimmune reaction causing Guillain-Barr syndrome, transverse myelitis or other serious injuries. […] An improperly administered vaccination may cause a serious side effect or shoulder injuries.
  • #95 Varicella Virus Vaccine – Adverse Effects of Vaccines – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK190012/
    The committee assesses the mechanistic evidence regarding an association between varicella vaccine and disseminated Oka VZV without other organ involvement in individuals with or without demonstrated immunodeficiencies as strong based on cases presenting definitive clinical evidence. […] Conclusion 5.1: The evidence convincingly supports a causal relationship between varicella vaccine and disseminated Oka VZV without other organ involvement. […] The committee has limited confidence in the epidemiologic evidence, based on one study that lacked validity and precision, to assess an association between varicella vaccine and vaccine-strain viral reactivation with subsequent infection resulting in meningitis or hepatitis. […] The committee concludes the clinical and biological evidence is strong in support of an association between varicella vaccine and vaccine-strain viral reactivation with subsequent infection resulting in meningitis or encephalitis based on six cases presenting definitive clinical evidence. […] Conclusion 5.4: The evidence convincingly supports a causal relationship between varicella vaccine and vaccine-strain viral reactivation with subsequent infection resulting in meningitis or encephalitis.
  • #96 Varicella Virus Vaccine – Adverse Effects of Vaccines – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK190012/
    The committee assesses the mechanistic evidence regarding an association between varicella vaccine and disseminated Oka VZV without other organ involvement in individuals with or without demonstrated immunodeficiencies as strong based on cases presenting definitive clinical evidence. […] Conclusion 5.1: The evidence convincingly supports a causal relationship between varicella vaccine and disseminated Oka VZV without other organ involvement. […] The committee has limited confidence in the epidemiologic evidence, based on one study that lacked validity and precision, to assess an association between varicella vaccine and vaccine-strain viral reactivation with subsequent infection resulting in meningitis or hepatitis. […] The committee concludes the clinical and biological evidence is strong in support of an association between varicella vaccine and vaccine-strain viral reactivation with subsequent infection resulting in meningitis or encephalitis based on six cases presenting definitive clinical evidence. […] Conclusion 5.4: The evidence convincingly supports a causal relationship between varicella vaccine and vaccine-strain viral reactivation with subsequent infection resulting in meningitis or encephalitis.
  • #97 Chickenpox Vaccine Side Effects & Reactions: Legal Help
    https://www.myvaccinelawyer.com/vaccine-injury-lawyer/resources/vaccine/chickenpox
    Chickenpox is an infection caused by the varicella-zoster virus. […] While there is no question that varicella vaccines are very effective at preventing chickenpox, unfortunately, many healthy children who get vaccinated also suffer dangerous chickenpox vaccine side effects. […] In some cases, complications from chickenpox vaccinations can lead to life-threatening illnesses and injuries. […] According to the CDC, getting the chickenpox vaccine is safer than getting chickenpox. Unfortunately, while this may be true for most people, many people suffer dangerous side effects after receiving the vaccine. […] Serious complications such as febrile seizures are also more common among ProQuad recipients and typically occur within five to twelve days after the first dose. […] Occasionally, recipients develop an autoimmune reaction causing Guillain-Barr syndrome, transverse myelitis or other serious injuries. […] An improperly administered vaccination may cause a serious side effect or shoulder injuries.
  • #98 Chickenpox Vaccine Side Effects & Reactions: Legal Help
    https://www.myvaccinelawyer.com/vaccine-injury-lawyer/resources/vaccine/chickenpox
    Chickenpox is an infection caused by the varicella-zoster virus. […] While there is no question that varicella vaccines are very effective at preventing chickenpox, unfortunately, many healthy children who get vaccinated also suffer dangerous chickenpox vaccine side effects. […] In some cases, complications from chickenpox vaccinations can lead to life-threatening illnesses and injuries. […] According to the CDC, getting the chickenpox vaccine is safer than getting chickenpox. Unfortunately, while this may be true for most people, many people suffer dangerous side effects after receiving the vaccine. […] Serious complications such as febrile seizures are also more common among ProQuad recipients and typically occur within five to twelve days after the first dose. […] Occasionally, recipients develop an autoimmune reaction causing Guillain-Barr syndrome, transverse myelitis or other serious injuries. […] An improperly administered vaccination may cause a serious side effect or shoulder injuries.
  • #99 Varicella Virus Vaccine – Adverse Effects of Vaccines – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK190012/
    The committee assesses the mechanistic evidence regarding an association between varicella vaccine and disseminated Oka VZV without other organ involvement in individuals with or without demonstrated immunodeficiencies as strong based on cases presenting definitive clinical evidence. […] Conclusion 5.1: The evidence convincingly supports a causal relationship between varicella vaccine and disseminated Oka VZV without other organ involvement. […] The committee has limited confidence in the epidemiologic evidence, based on one study that lacked validity and precision, to assess an association between varicella vaccine and vaccine-strain viral reactivation with subsequent infection resulting in meningitis or hepatitis. […] The committee concludes the clinical and biological evidence is strong in support of an association between varicella vaccine and vaccine-strain viral reactivation with subsequent infection resulting in meningitis or encephalitis based on six cases presenting definitive clinical evidence. […] Conclusion 5.4: The evidence convincingly supports a causal relationship between varicella vaccine and vaccine-strain viral reactivation with subsequent infection resulting in meningitis or encephalitis.
  • #100 Chickenpox Vaccine Side Effects & Reactions: Legal Help
    https://www.myvaccinelawyer.com/vaccine-injury-lawyer/resources/vaccine/chickenpox
    Chickenpox is an infection caused by the varicella-zoster virus. […] While there is no question that varicella vaccines are very effective at preventing chickenpox, unfortunately, many healthy children who get vaccinated also suffer dangerous chickenpox vaccine side effects. […] In some cases, complications from chickenpox vaccinations can lead to life-threatening illnesses and injuries. […] According to the CDC, getting the chickenpox vaccine is safer than getting chickenpox. Unfortunately, while this may be true for most people, many people suffer dangerous side effects after receiving the vaccine. […] Serious complications such as febrile seizures are also more common among ProQuad recipients and typically occur within five to twelve days after the first dose. […] Occasionally, recipients develop an autoimmune reaction causing Guillain-Barr syndrome, transverse myelitis or other serious injuries. […] An improperly administered vaccination may cause a serious side effect or shoulder injuries.