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• #1 Key Facts About Seasonal Flu Vaccine | Influenza (Flu) | CDC

  https://www.cdc.gov/flu/vaccines/keyfacts.html

  Influenza (flu) is a potentially serious disease that can lead to hospitalization and sometimes even death. […] Flu vaccination has been shown to have many benefits including reducing the risk of flu illnesses, hospitalizations and even the risk of flu-related death. […] An annual seasonal flu vaccine is the best way to help reduce the risk of getting flu and any of its potentially serious complications. […] Vaccination has been shown to have many benefits including reducing the risk of flu illnesses, hospitalizations and even the risk of flu-related death. […] For people 65 years and older, there are three flu vaccines that are preferentially recommended over standard-dose, unadjuvanted flu vaccines. […] This recommendation was based on a review of available studies which suggests that, in this age group, these vaccines are potentially more effective than standard dose unadjuvanted influenza vaccines.

• #2 2024-25 Flu Season – Vaccinate Your Family 2024-25 Flu Season – Vaccinate Your Family

  https://vaccinateyourfamily.org/vaccines-diseases/current-flu-season/

  Flu vaccination is recommended for everyone 6 months and older each year – get your flu shot before flu begins circulating in your community for the best protection. […] On average every year in the U.S., flu results in millions of illnesses, hundreds of thousands of hospitalizations, and tens of thousands of deaths. Aside from COVID-19, flu is the deadliest vaccine-preventable disease in the U.S. […] Annual flu vaccination is recommended for everyone six months and older, with rare exception. Flu vaccines have been updated this season to help protect against three circulating strains of flu. […] Vaccination is the best defense we have against flu-related illness, hospitalization, and death. Getting vaccinated helps protect YOU, your loved ones, and your community! […] There is a preferential flu vaccine recommendation to better protect people aged 65 years and older. Older adults should receive a high-dose, adjuvanted, or recombinant flu vaccine.

• #3 Flu shot facts and side effects | Live Science

  https://www.livescience.com/40279-flu-shot-information.html

  „Pregnant women, when they get influenza, have a tendency to get a more severe disease” and are at increased risk for complications and hospitalization from the disease, Schaffner said. […] The flu is certainly a very serious disease. […] Every year, between 15 million and 60 million cases of the flu are reported in the U.S., Cunningham said. More than 200,000 people with the flu are admitted to hospitals yearly, and between 3,000 and 50,000 people in the U.S. die of the flu annually.

• #4 Flu Shot | Flu | Influenza | MedlinePlus

  https://medlineplus.gov/flushot.html

  The flu (influenza) is a respiratory infection. It is caused by influenza viruses that infect your nose, throat, and lungs. These viruses can spread from person to person. […] Getting vaccinated against the flu each year is best way to lower your risk of the flu and its complications. […] The flu vaccine causes your immune system to make antibodies about two weeks after you get the shot. These antibodies provide protection against infection with the flu viruses that are in the vaccine. […] Flu shots are especially important for people who are at high risk of developing serious complications from the flu. […] You need to get a flu shot every year because your immune protection from the vaccine declines over time. You need to get the shot every year to boost that protection. […] Flu viruses are constantly changing, so every year, the flu vaccine is updated. The flu vaccine will include protection against the viruses that will most likely be common during the upcoming flu season. […] Flu vaccines have been shown to be safe. But like any medical product, they can cause side effects.

• #5 Flu Vaccines – Together by St. Jude™

  https://together.stjude.org/en-us/medical-care/immunity-illness-infection/flu-vaccine.html

  A flu vaccine protects people from developing influenza (flu). Flu is a contagious respiratory (breathing) illness. A flu vaccine causes a person to develop antibodies that recognize and fight flu viruses. This builds up the bodys natural defenses (immunity) against infection. […] A vaccine strengthens the immune system to protect the body from illness. The flu vaccine helps protect people from developing the flu. […] Flu vaccines do not give you the flu. Side effects are usually mild and go away after a few days. This is because the immune system is responding to the vaccine. The body is making antibodies against the flu. […] The flu vaccine is a safe and effective way to help prevent the flu.

• #6 Flu shot ingredients: What they contain and why

  https://www.medicalnewstoday.com/articles/321207

  Aluminum salts are adjuvants they help the body develop a stronger immune response against the virus in the vaccine. […] Thimerosal is a preservative, and it keeps vaccines from becoming contaminated. […] The flu vaccine cannot cause the flu because it contains either inactivated or weakened viruses that are no longer infectious or synthetic, lab-made variants. […] Flu shots contain various ingredients that work together to ensure that the vaccine is safe and effective.

• #7 The Flu Vaccine: A Courageous Step to Safeguard Your Family

  https://coynemedical.com/the-flu-vaccine-protecting-you-and-your-family/

  The Flu vaccine is developed annually, based on research and recommendations from the World Health Organisation, who continuously monitor flu strains across the world. […] The efficacy of the flu vaccine is influenced by a number of factors, including age, other health conditions and how closely matched the flu strains in circulation and the vaccine are. […] Vaccination reduces the the risk of these complications and subsequently reduces rates of hospitalisations and ITU admissions due to infection. […] Given that flu vaccination can help reduce the risk of flu, severity of flu and risk of complications, it helps reduce the costs associated with the treatment of flu and its complications. […] The vaccines either contain inactivated flu strains, weakened forms of the virus or genetic material from a virus.

• #8 8 things doctors wish patients knew about flu vaccines | American Medical Association

  https://www.ama-assn.org/delivering-care/public-health/8-things-doctors-wish-patients-knew-about-flu-vaccines

  The flu vaccine is made of pieces of the virus or inactivated virus, and the nasal spray is a whole virus, but its an attenuated form of the virus, so neither kind can actually give you the flu, said Dr. Kirley. […] Patients will sometimes coincidentally come down with the flu shortly after receiving the vaccination, but thats just a quirk of timing, Dr. Kirley said, noting that this is one of many common misconceptions about influenza and flu vaccines. […] Every year, influenza causes hundreds of thousands of hospitalizations and tens of thousands of deaths in the United States, she said, noting that its important to do everything we can to keep people out of the hospital and getting a flu shot is one of the best things we can do to stay healthy during flu season. […] The flu vaccine is really to get the protection against that scenario.

• #9 Your Child’s Vaccines: Influenza (Flu) Vaccine (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/flu-vaccine.html

  The nasal spray flu vaccine contains weakened live flu viruses. So it may cause mild cold-like symptoms, such as a runny nose, sore throat, or tiredness. […] In the past, people with an egg allergy had to check with their doctor about whether the flu vaccine was OK for them because it’s grown inside eggs. But health experts now say that the amount of egg protein in the vaccine is so tiny that it’s safe even for kids with a severe egg allergy. […] During the COVID-19 pandemic, fewer people got infected or were hospitalized with viral respiratory infections like the flu and RSV. […] So it’s more important than ever to get a flu vaccine and an updated COVID-19 vaccine.

• #10 Why You Should Get Your Flu Shots Early This Year (and Every Year)! | Children’s Hospital of Philadelphia

  https://www.chop.edu/news/health-tip/influenza-what-you-should-know-about-flu

  Flu season is on the horizon and while everyone may be familiar with the influenza virus and how lousy it feels to be in bed with the flu, there are some myths about influenza and the influenza vaccine that persist year after year. […] The influenza vaccine isn’t perfect, and it is possible, although unlikely, that you can become ill with the flu even if you have received the vaccine. However, if you get the influenza vaccine and still get the flu, your symptoms are likely to be much less severe than if you skipped the vaccine altogether. […] The influenza virus changes as it replicates. That means each flu season, the strains of the virus circulating may be different enough that immunity from previous vaccinations or infections is no longer protective. […] The influenza vaccine shot doesn’t contain live viruses, so it can’t cause the flu. Although the nasal spray version does contain live, weakened influenza vaccine viruses, these viruses cannot enter the bloodstream or reproduce themselves in the lungs to cause an infection.

• #11 Flu shot: Your best bet for avoiding influenza

  https://www.mayoclinic.org/diseases-conditions/flu/in-depth/flu-shots/art-20048000

  Getting a flu vaccine is the best way to prevent the flu and its complications for almost everyone. The flu vaccine can lower the risk of getting the flu. […] Flu viruses change quickly. Last year’s vaccine may not protect you from this year’s viruses. New flu vaccines are released every year to keep up with rapidly changing flu viruses. […] Getting a yearly flu vaccine lowers the chances of having serious complications or dying of the flu. This is especially true for people who are at high risk of flu complications. […] For almost everyone, a flu vaccine can lower the risk of the flu and its complications. […] How well the flu vaccine works to protect you from the flu can vary. Reviews of flu season data since 2009 find that vaccine protection ranges from a low of 22% to a high of 56%. […] The flu vaccine can’t give you the flu. And the flu vaccine does not make you more likely to get another respiratory infection based on available evidence.

• #12 Key Facts About Seasonal Flu Vaccine | Influenza (Flu) | CDC

  https://www.cdc.gov/flu/vaccines/keyfacts.html

  Vaccination to prevent influenza and its potentially serious complications is particularly important for people who are at higher risk of developing serious influenza complications. […] A flu vaccine is needed every year for two reasons. First, a person’s immune protection from vaccination declines over time, so an annual flu vaccine is needed for optimal protection. Second, because influenza viruses are constantly changing, the composition of flu vaccines is reviewed annually, and vaccines are updated to protect against the viruses that research indicates will be most common during the upcoming flu season. […] However, the benefits of flu vaccination will still vary, depending on characteristics of the person being vaccinated (for example, their health and age), what influenza viruses are circulating that season and, potentially, which type of flu vaccine was used. […] Flu vaccination has been shown in studies to reduce severity of illness in people who get vaccinated but still get sick.

• #13 Frequently Asked Questions about Flu Vaccines | Baltimore City Health Department

  https://health.baltimorecity.gov/flu/frequently-asked-questions-about-flu-vaccines

  The flu vaccine is safe for most people and is recommended for everyone ages 6 months and older. […] No, a flu vaccine cannot cause flu illness. […] Flu vaccines cause antibodies to develop in the body about two weeks after vaccination. […] A flu vaccine is needed every season for two reasons. First, a persons immune protection from vaccination declines over time, so an annual vaccine is needed for optimal protection. Second, because flu viruses are constantly changing, flu vaccines may be updated from one season to the next to protect against the viruses that research suggests may be most common during the upcoming flu season. […] Unfortunately, some people can become infected with a flu virus a flu vaccine is designed to protect against, despite getting vaccinated. […] Flu vaccination has been shown in some studies to reduce the severity of illness in people who get vaccinated but still get sick.

• #14 Influenza (flu) – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/flu/symptoms-causes/syc-20351719

  Flu, also called influenza, is an infection of the nose, throat and lungs, which are part of the respiratory system. The flu is caused by a virus. […] Influenza is caused by viruses. These viruses travel through the air in droplets when someone with the infection coughs, sneezes or talks. You can inhale the droplets directly. Or you can pick up the virus from touching an object, such as a computer keyboard, and then touching your eyes, nose or mouth. […] A person’s first flu infection gives some long-term protection against similar strains of flu. But the vaccines offered each year are made to match the flu virus strains that are most likely to spread that season. The protection these vaccines offer lasts for months in most people.

• #15 Influenza (flu) – immunisation | Better Health Channel

  https://www.betterhealth.vic.gov.au/health/healthyliving/flu-influenza-immunisation

  Influenza (flu) is caused by a highly contagious virus that is spread by contact with fluids from coughs and sneezes. Every year, the flu causes widespread illness in the community. […] The flu vaccine protects you, your family, and the community. It also helps reduce the risk of severe illnesses and flu related complications. […] Influenza immunisation provides protection against influenza and helps reduce the number of infections and deaths. […] Vaccination is key to protecting yourself and those around you from the flu. […] The flu vaccine cannot give you the flu because it does not contain live virus. Some people may still contract the flu because the vaccine may not always protect against all strains of the influenza virus circulating in the community. […] Flu viruses change every year because the flu virus has a unique ability to change its surface structure. This means that even if you had the flu or an immunisation one year, your body’s immune system might be unable to fight the changed version of the virus that will be circulating the following year.

• #16 Flu shot facts and side effects | Live Science

  https://www.livescience.com/40279-flu-shot-information.html

  The seasonal flu shot is a yearly vaccine administered to protect against the flu, or influenza. In the United States, flu shots are recommended for everyone ages 6 months and older, according to the Centers for Disease Control and Prevention (CDC). […] The flu can be a very serious illness, especially in young children, adults ages 65 and over, those with underlying health conditions and pregnant women. The flu shot is the best way to protect yourself and your family from the flu, according to the CDC. […] Strains of the flu virus are constantly changing, so a new flu vaccine is made each year. Scientists make the vaccine before the flu season starts by predicting which flu strains are likely to be the most common during the upcoming season. […] „Since the flu virus frequently drifts in its genetic composition, you have to reformulate the vaccine, and this is one of the reasons that people have to [get a flu shot] on an annual basis,” Dr. William Schaffner, a preventive medicine and infectious disease expert at the Vanderbilt University School of Medicine in Tennessee told Live Science.

• #17 Flu Vaccine (Flu Shot) Side Effects, Effectiveness, When to Get It, Ingredients

  https://www.medicinenet.com/flu_vaccination/article.htm

  The flu vaccine is effective against influenza 2 weeks after administration. […] The vaccine is generally effective against the influenza virus within two weeks of administration. […] The vaccine is only effective against the strains of the virus that match the vaccine. […] The seasonal flu vaccine effectiveness is dependent upon the extent of the match between the virus strains used to prepare the vaccine and those viruses in actual circulation in the community. […] The effectiveness of the flu vaccine is dependent upon the extent of the match between the virus strains used to prepare the vaccine and those viruses in actual circulation. […] While vaccine effectiveness can vary, recent studies show vaccine reduces the risk of flu illness by about 40%-60% among the overall population during seasons when most circulating flu viruses are similar to those used in the vaccines.

• #18 Influenza vaccine – Wikipedia

  https://en.wikipedia.org/wiki/Influenza_vaccine

  Influenza vaccines, colloquially known as flu shots, are vaccines that protect against infection by influenza viruses. New versions of the vaccines are developed twice a year, as the influenza virus rapidly changes. While their effectiveness varies from year to year, most provide modest to high protection against influenza. Vaccination against influenza began in the 1930s, with large-scale availability in the United States beginning in 1945. […] Both the World Health Organization and the US Centers for Disease Control and Prevention (CDC) recommend yearly vaccination for nearly all people over the age of six months, especially those at high risk, and the influenza vaccine is on the World Health Organization’s List of Essential Medicines. […] The vaccines are generally safe, including for people who have severe egg allergies. A common side effect is soreness near the site of injection. Fever occurs in five to ten percent of children vaccinated, and temporary muscle pains or feelings of tiredness may occur.

• #19 Flu shot ingredients: What they contain and why

  https://www.medicalnewstoday.com/articles/321207

  Flu shots contain tiny amounts of inactive, or dead, flu virus. […] The viruses that cause the flu, known as influenza viruses, are constantly changing. […] Many studies over the years have shown that flu vaccines are safe and effective, reducing flu cases and related hospitalizations. […] The presence of these inactive viruses triggers the body’s natural defense mechanism the immune system which produces antibodies to fight these viruses. […] Traditional flu shots are trivalent, or three-component, vaccines. […] The specific viruses in an annual shot depend on which are likely to circulate during that year’s flu season. Researchers make this prediction. […] Formaldehyde’s role in a flu shot is to inactivate toxins from viruses and bacteria that may contaminate the vaccine during production.

• #20 How Effective Is the Flu Shot?

  https://www.ncoa.org/article/how-effective-is-the-flu-shot/

  The flu vaccine provides protection against infection with flu viruses. […] Each year, the flu vaccine is reformulated to combat the strains predicted to be most common in the upcoming flu season. […] Flu shot efficacy can vary from year to year, depending on how well it matches circulating strains. However, it typically ranges from 40-60%. […] A 2021 study showed that among adults, vaccination was associated with a 26% lower risk of flu-related intensive-care unit (ICU) admission and a 31% lower risk of flu-related death compared to those who did not receive the flu vaccine. […] According to CDC, vaccination against the flu has also been linked to lower rates of hospitalization for people with chronic lung disease and diabetes. […] CDC and the Advisory Committee on Immunization Practices (ACIP) recommend adults age 65 and older receive one of three high-dose flu vaccines over standard-dose options, since these may offer stronger protection.

• #21 Misconceptions about Seasonal Flu and Flu Vaccines | NYP

  https://www.nyp.org/pediatrics/tip-sheets/misconceptions-about-seasonal-flu-and-flu-vaccines

  The flu vaccine only protects against influenza viruses, not other viruses. […] The ability of a flu vaccine to protect a person depends largely on the similarity or match between the viruses selected to make the vaccine and those spreading and causing illness. […] The final explanation for experiencing flu-like symptoms after vaccination is that unfortunately, the flu vaccine doesn’t always provide adequate protection against the flu. This is more likely to occur among people that have weakened immune systems or people age 65 and older.

• #22 2024-25 Flu Season – Vaccinate Your Family 2024-25 Flu Season – Vaccinate Your Family

  https://vaccinateyourfamily.org/vaccines-diseases/current-flu-season/

  Flu can cause severe illness in pregnant women due to changes in the immune system, heart, and lungs during pregnancy. […] People 65 years and older account for 50 – 70% of flu-related hospitalizations and 70 – 85% of flu-related deaths. […] People living with chronic medical conditions such as asthma, diabetes, heart disease, lung disease, and chronic kidney disease are at an increased risk of severe flu-related outcomes like hospitalization and death. […] The effectiveness of the flu vaccines varies from year-to-year. It depends on several things including which flu viruses are spreading, your age, and if you have certain health conditions or take certain medications that weaken your immune system. Typically, flu vaccination helps prevent illness 40-60% of the time if flu vaccines are well-matched to the circulating viruses. Even during the seasons when the flu vaccines don’t perfectly match the circulating flu strains, the vaccines still help prevent serious flu-related complications like hospitalization and death.

• #23 Factors affecting immune responses to the influenza vaccine

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5861809/

  Annual administration of the seasonal influenza vaccine is strongly recommended to reduce the burden of disease, particularly for persons at the highest risk for the viral infection. […] Even during years when there is a good match between the vaccine and circulating strains, host-related factors such as age, preexisting immunity, genetic polymorphisms, and the presence of chronic underlying conditions may compromise influenza vaccine responsiveness. […] In addition, preexisting immunity and genetic and hormonal factors may account for the inter-individual variability with respect to the immunological parameters used for assessing vaccine responsiveness. […] Overall, influenza exposure history based on prior infections and vaccinations heavily contributes to the complexity of the polyclonal antibody response to influenza viral strains in humans. […] Several host-related factors such as age, genetic polymorphisms, and the presence of chronic underlying conditions may contribute to a decline in immune responses and consequently compromise influenza vaccine responsiveness.

• #24 How Effective Is the Flu Shot?

  https://www.ncoa.org/article/how-effective-is-the-flu-shot/

  Older adults (age 65+) are at higher risk for flu complications that can lead to hospitalization and even death. […] Each year, the flu vaccine is updated to protect against the most common strains circulating in the environment. […] While the flu shots effectiveness can vary, it still offers strong and potentially life-saving protection against the virus. […] According to the Centers for Disease Control and Prevention (CDC), people age 65 and older accounted for 51% of hospitalizations and 68% of deaths during the 2023-2024 flu season. […] There are two main reasons were more vulnerable to the flu later in life. One is that aging causes our immune system to become less efficient at fighting viruses. In addition, were more prone to having one or more chronic conditions that can be worsened by influenza.

• #25 2024-25 Flu Season – Vaccinate Your Family 2024-25 Flu Season – Vaccinate Your Family

  https://vaccinateyourfamily.org/vaccines-diseases/current-flu-season/

  Flu vaccination is recommended for everyone 6 months and older each year – get your flu shot before flu begins circulating in your community for the best protection. […] On average every year in the U.S., flu results in millions of illnesses, hundreds of thousands of hospitalizations, and tens of thousands of deaths. Aside from COVID-19, flu is the deadliest vaccine-preventable disease in the U.S. […] Annual flu vaccination is recommended for everyone six months and older, with rare exception. Flu vaccines have been updated this season to help protect against three circulating strains of flu. […] Vaccination is the best defense we have against flu-related illness, hospitalization, and death. Getting vaccinated helps protect YOU, your loved ones, and your community! […] There is a preferential flu vaccine recommendation to better protect people aged 65 years and older. Older adults should receive a high-dose, adjuvanted, or recombinant flu vaccine.

• #26 Flu Facts and Vaccination Clinic | Cal State LA

  https://www.calstatela.edu/studenthealthcenter/flu-facts-and-vaccination-clinic

  Vaccination is the best way to protect yourself and others from influenza (the flu). […] Seasonal flu is a contagious respiratory illness caused by influenza viruses. […] Flu spreads when a person with the flu coughs, sneezes, or talks and droplets containing their germs land in your mouth or nose. […] Seniors (those age 65 and older), children (especially those younger than 5), people with chronic health conditions, and pregnant individuals are among those who are more likely to experience flu-related complications serious, potentially life-threatening conditions. […] Each year more than 140,000 people are hospitalized for flu-related complications in the United States. […] Together, flu and pneumonia (a flu complication) are typically in the ten leading causes of death in the U.S. […] Vaccination is the best way to protect yourself from the flu, but there are additional steps you can take to help protect yourself and others.

• #27 Flu shot facts and side effects | Live Science

  https://www.livescience.com/40279-flu-shot-information.html

  „Pregnant women, when they get influenza, have a tendency to get a more severe disease” and are at increased risk for complications and hospitalization from the disease, Schaffner said. […] The flu is certainly a very serious disease. […] Every year, between 15 million and 60 million cases of the flu are reported in the U.S., Cunningham said. More than 200,000 people with the flu are admitted to hospitals yearly, and between 3,000 and 50,000 people in the U.S. die of the flu annually.

• #28 Causes and Relief Tips for a Swollen Arm After a Flu Shot

  https://www.myvaccinelawyer.com/vaccine-injury-lawyer/resources/vaccine/swollen-arm-after-a-flu-shot

  Flu shots can cause arm swelling due to your body’s immune response, but if the swelling worsens or persists, it may signal a more serious issue requiring medical attention. […] A swollen arm is one of the most common side effects of a flu shot, but why does it happen? After a flu vaccination, some individuals experience redness, swelling, or soreness at the injection site. These symptoms are typically mild and temporary, but in some cases, prolonged pain or severe swelling may indicate a more serious reaction. […] The flu vaccine works by stimulating the immune system to build protection against the influenza virus. This immune response can lead to arm soreness, swelling, and mild discomfort, as the body reacts to the vaccine ingredients. […] A sore arm after a flu shot is a direct result of the immune response triggered by the influenza vaccine. When the flu vaccine is injected into the arm muscle, the body recognizes the vaccine components as foreign and begins producing antibodies. This immune system reaction can lead to temporary swelling, soreness, and discomfort at the injection site.

• #29 32 Myths About The Flu Vaccine You Don’t Need To Fear : Shots – Health News : NPR

  https://www.npr.org/sections/health-shots/2014/10/10/354627818/32-myths-about-the-flu-vaccine-you-dont-need-to-fear

  Even if the flu in a future season resembles a strain you’ve had before, the protection is likely to be incomplete and fades over time. Flu weakens your immune system while your body is fighting it and puts others at risk. […] There’s no evidence flu vaccines have a major effect on virus mutations. […] The most common side effects of the flu shot are mild, such as headache, fatigue, cough, low fever and arm soreness lasting a couple of days. Fewer than one in a million people experience severe allergic reactions. […] Getting the flu shot any time during flu season will reduce your risk of getting the flu.

• #30 Influenza vaccinations – ACT Government

  https://www.act.gov.au/health/topics/immunisation/influenza-vaccinations

  Influenza vaccines don’t cause the influenza. The influenza vaccine cannot give you influenza. The vaccine does not contain live influenza virus. […] Some people mistakenly believe that the vaccine causes influenza, reasons for this can include: An immune response is triggered following vaccination. In some people this may produce mild flu-like symptoms, like fever or headache, for a few days after the vaccine. These symptoms are much milder than the symptoms of actual influenza. […] It takes 2 weeks following vaccination for the body’s immune system to produce protection. Some people may develop influenza during this period because they have come into contact with the influenza virus before or soon after vaccination, but before developing protection. […] The common cold or other respiratory viruses may be confused with influenza. The influenza vaccine only protects you against the influenza virus.

• #31 Immunization Safety Review: Influenza Vaccines and Neurological Complications – Immunization Safety Review – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK222009/

  Immunization Safety Review: Influenza Vaccines and Neurological Complications. […] This seventh report from the committee examines the hypothesis that influenza vaccines are associated with an increased risk of neurological complications, particularly Guillain-Barr syndrome (GBS) and multiple sclerosis (MS). […] The committee is charged with assessing both the scientific evidence regarding the hypotheses under review and the significance of the issues for society. […] The scientific assessment has two components: (1) an examination of the epidemiologic and clinical evidence regarding a possible causal relationship between exposure to the vaccine and the adverse event; and (2) an examination of theory and experimental or observational evidence from in vitro, animal, or human studies regarding biological mechanisms that might be relevant to the hypothesis.

• #32 Everything You Need to Know About Flu Shots – BuzzRx

  https://www.buzzrx.com/blog/4-flu-shot-side-effects-to-know

  Flu vaccines (also called flu shots) are the best way to protect against the influenza viruses that are expected to be the most common during the upcoming flu season. […] Flu vaccination also reduces the severity of the illness in case you get the flu. […] Flu vaccination has an excellent safety record. […] Very rarely, flu shots can cause more serious adverse effects, such as Guillain-Barre syndrome, a rare neurologic condition in which the immune system attacks healthy nerve cells. […] There may be a possible association between flu vaccination and Guillain-Barre syndrome (GBS), a rare neurologic condition in which the immune system attacks healthy nerve cells. However, the risk of this severe illness happening is very small.

• #33 How Long After Flu Shot Does Guillain-Barré Syndrome Develop?

  https://www.myvaccinelawyer.com/vaccine-injury-lawyer/resources/vaccine/flu/gbs

  If you’re thinking about getting a flu shot, it’s good to know that Guillain-Barr Syndrome (GBS) is a very rare side effect, occurring in only about one or two people out of every million who get the vaccine. […] The exact cause of Guillain-Barr Syndrome (GBS) following a flu shot is not fully understood. However, it is believed to be related to an immune response triggered by the vaccine. GBS is an autoimmune disorder where the immune system mistakenly attacks the peripheral nerves. In some cases, the immune response stimulated by the flu shot can lead to inflammation and damage to the nerves, resulting in GBS. […] There have been instances where GBS has occurred following the administration of the influenza vaccine. However, it’s important to note that the risk of developing GBS after receiving the flu shot is very low, estimated to be around 1 or 2 cases per million vaccinated individuals.

• #34 Influenza: The Disease & Vaccines | Children’s Hospital of Philadelphia

  https://www.chop.edu/vaccine-education-center/vaccine-details/influenza-vaccine

  The influenza vaccine is unusual in that most years a different vaccine is made. Because strains of influenza virus that circulate in the community often differ from one season to the next, the vaccine must change to best protect against those different strains. […] The data have been mixed regarding whether influenza vaccine can cause Guillain-Barr syndrome (GBS); however, it is now generally agreed that very rarely, people can get GBS after receiving the influenza vaccine. However, people can also experience GBS after viral infections, including influenza, and the rates of GBS are about 17 times higher after infection than vaccination. […] Every year, between 75 and 150 previously healthy children die after becoming infected with influenza; therefore, the benefits of getting the influenza vaccine outweigh the risks.

• #35 Are You Having an Allergic Reaction to the Flu Shot?

  https://www.verywellhealth.com/allergic-reaction-to-the-flu-vaccine-4112324

  Allergic reactions to the flu shot are very rare. If you do experience one, you may have symptoms such as trouble breathing, wheezing, skin rash or hives, and rapid heartbeat. […] While it is possible to have an allergic reaction to a flu vaccine, it’s rare. According to the Centers for Disease Control and Prevention (CDC), an allergy to the flu vaccine affects only one or two people out of every million doses. […] A true allergy is one in which the immune system produces defensive antibodies to fight off an otherwise harmless substance. Serious allergic reactions can result in anaphylaxis, a potentially life-threatening condition. […] Most flu shots and the nasal spray vaccine FluMist are manufactured using egg-based technology. They contain trace amounts of an egg protein called ovalbumin, a substance that 1.3% of children and 0.2% of adults are allergic to.

• #36 Immunization Safety Review: Influenza Vaccines and Neurological Complications – Immunization Safety Review – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK222009/

  The Immunization Safety Review Committee was asked to examine the hypothesis that a causal relationship might exist between receipt of influenza vaccines and neurological complications. […] The committee concluded that the evidence favors acceptance of a causal relationship between 1976 swine influenza vaccines and Guillain-Barr syndrome in adults. […] The committee examined reports on epidemiological studies of the risk of MS relapses following influenza vaccination; separately it examined a smaller set of reports concerning the risk of MS onset. […] The committee concludes that the evidence favors rejection of a causal relationship between influenza vaccines and relapse of multiple sclerosis. […] The committee concludes that the evidence is inadequate to accept or reject a causal relationship between influenza vaccines and optic neuritis in adults.

• #37 Flu Shot Frequently Asked Questions | Atrium Health Wake Forest Baptist

  https://www.wakehealth.edu/condition/f/flu/flu-shot-faq

  Seasonal influenza vaccines have been associated with Guillain-Barr syndrome (GBS) in 1 per 1,000,000 people vaccinated. Recent data suggest that getting the flu and not the vaccines may be one of the causes of GBS. […] However, when vaccines are well matched, they can reduce the chances of getting the flu by nearly 90 percent.

• #38 Causes of Vaccine Hesitancy in Adults for the Influenza and COVID-19 Vaccines: A Systematic Literature Review

  https://www.mdpi.com/2076-393X/10/9/1518

  Causes of Vaccine Hesitancy in Adults for the Influenza and COVID-19 Vaccines: A Systematic Literature Review […] Background: Vaccine hesitancy was labelled as one of the top ten threats to global health by the World Health Organization in 2019 and is associated with negative health outcomes. Previous reviews on cause of vaccines have not included vaccine hesitancy related to the COVID-19 vaccine. This review aimed to fill this gap by synthesising the findings of studies identifying causes of vaccine hesitancy to the COVID-19 and influenza vaccines. […] Results: Fourteen papers were included. Four themes were identified as causes of vaccine hesitancy comprising: concerns over safety, lack of trust, lack of need for vaccination and cultural reasons. While concerns over safety were found in all countries, some of these were specific to particular countries and cultures. Our findings suggest that scientific knowledge of vaccines and size of clinical trials during their development reduce vaccine hesitancy. However, pharmaceutical companies were not a trusted source of information.

• #39 5 myths about the flu vaccine

  https://www.who.int/news-room/spotlight/influenza-are-we-ready/5-myths-about-the-flu-vaccine

  As many as 650 000 people a year can die of the flu. This only represents respiratory deaths, so the likely impact is even higher. […] The injected flu vaccine contains an inactivated virus that cannot give you influenza. […] The flu vaccine is proven to be safe. Severe side effects are extremely rare. […] Several flu viruses are circulating all the time, which is why people may still get the flu despite being vaccinated since the vaccine is specific to one strain. […] Pregnant women should especially get the flu vaccine since their immune systems are weaker than usual. The inactivated flu vaccine is safe at any stage of pregnancy.

• #40 Misconceptions about Seasonal Flu and Flu Vaccines | NYP

  https://www.nyp.org/pediatrics/tip-sheets/misconceptions-about-seasonal-flu-and-flu-vaccines

  No, a flu shot cannot cause flu illness. The influenza viruses contained in a flu shot are inactivated (killed), which means they cannot cause infection. […] Unlike the flu shot, the nasal spray vaccine does contain live viruses. However, the viruses contained in the nasal spray flu vaccine are attenuated (i.e., weakened), which means they cannot cause flu illness. […] No. Flu is a serious disease, particularly among young children, older adults, and people with certain chronic health conditions, such as asthma, heart disease or diabetes. Any flu infection can carry a risk of serious complications, hospitalization or death, even among otherwise healthy children and adults. Therefore, getting vaccinated is a safer choice than risking illness to obtain immune protection. […] Yes. CDC recommends a yearly flu vaccine for just about everyone 6 months and older, even when the viruses the vaccine protects against have not changed from the previous season. The reason for this is that a persons immune protection from vaccination declines over time, so an annual vaccination is needed to get the optimal or best protection against the flu.

• #41 Is the flu shot safe? Myths, facts, side effects, and risks

  https://www.medicalnewstoday.com/articles/312469

  Flu occurs due to influenza viruses. This infection can have serious and even life threatening complications, especially for older adults, young children, and people with certain medical conditions. […] Flu shots contain killed, or inactivated, flu viruses. They are not able to cause flu. These viruses activate the immune system to create proteins called antibodies. […] The flu shot can cause symptoms similar to those of flu, such as a headache or nausea, but it cannot give the person flu. […] However, according to the CDC, studies have shown that there is no link between vaccination and autism. […] Despite controversies over the safety of flu shots, scientific evidence supports them as safe and effective ways for preventing seasonal flu.

• #42 Study: Some Parents Believe Flu Vaccine is Conspiracy, Causes AutismCalifornia Consumer Privacy Act (CCPA) Opt-Out Icon

  https://www.usnews.com/news/health-care-news/articles/2018-10-18/study-some-parents-believe-flu-vaccine-is-conspiracy-causes-autism

  However, some parents remain hesitant, with 28 percent saying the flu shot can cause autism. […] Moorjani said that after years of research, healthcare professionals „know that the flu vaccine is safe.” […] „The flu shot does not cause autism or any other diseases or illnesses,” Moorjani said. „Doctors recommend the flu shot because it is the best way to protect you and your family from the flu.”

• #43 Flu shot does not increase risk of getting the virus | Fact Check

  https://factcheck.afp.com/doc.afp.com.36JN78V

  The influenza vaccine does not increase one’s risk of getting the virus — nor does it permanently damage the immune and nervous systems, contrary to claims in a clip circulating online. The shots have a proven safety record and health experts recommend vaccination to prevent illness, hospitalization and death. […] „In terms of causing the flu, it doesn’t cause the flu, and causing neurological problems — it does not.” […] There is no evidence the vaccine causes long-term damage to the immune system. A 2017 study of health care workers found those who got the flu shot every year actually seemed to have a better immune response to the virus than those who were vaccinated only once (archived here). […] „The fact is you can prevent illness, medical visits, hospitalizations and death by vaccinating,” Walter said. „The vaccine works. Is it perfect? No. But it does work.”

• #44 32 Myths About The Flu Vaccine You Don’t Need To Fear : Shots – Health News : NPR

  https://www.npr.org/sections/health-shots/2014/10/10/354627818/32-myths-about-the-flu-vaccine-you-dont-need-to-fear

  Neurological side effects linked to flu vaccination are extremely rare; children with neurological disorders are actually at the highest risk for flu complications. […] Influenza can cause fever, muscle aches, cough, headaches and a sore throat for one to two weeks. […] Otherwise healthy people do die from the flu. The elderly and young children are most vulnerable. […] People with egg allergies can get a flu shot but should consult their doctor or allergist on options if their allergy is severe. […] The flu shot cannot offer 100 percent protection against the flu, but it reduces your risk of getting it. […] You can’t predict whether you’ll get the flu. […] A good diet and good hygiene are healthful habits that reduce the risk of illness but cannot prevent the flu on their own.

• #45 Flu Vaccine Myths – Pediatric Associates of Richmond

  https://parpeds.com/library/flu-vaccine-myths/

  Flu shots do not have any live influenza virus in them, and therefore cannot give you the flu. […] The vaccine contains a protein that lives on the surface of the influenza virus. […] Your immune system makes antibodies to this protein after you get vaccinated. […] The fact that protection is as high as 60% in some seasons is a testament to the hard work and research done year-round by these scientists. […] Yes, its true, people may get the flu even if they had the vaccine. However, their course of illness is generally more mild than it would have been had they not had the vaccine. […] Getting a flu vaccine the week after you recover would still help protect you against the 3 other strains for the rest of the flu season. […] While most healthy individuals who get the flu have a self-limited illness from which they recover just fine, that is not always the case. […] Vaccinating yourselves and your children provides some herd immunity to protect high-risk individuals who cant get the vaccine.

• #46 Influenza Vaccine: Benefits & Side Effects

  https://my.clevelandclinic.org/health/drugs/18888-influenza-virus-vaccine-injection

  The influenza vaccine reduces your risk of getting influenza or the flu. […] The vaccine only helps protect you against some strains of the flu. […] You may still catch the flu, but the illness is not usually as bad. You cannot get the flu from the vaccine. The vaccine will not protect against colds or other illnesses that may cause fever. The vaccine is needed every year.

• #47 32 Myths About The Flu Vaccine You Don’t Need To Fear : Shots – Health News : NPR

  https://www.npr.org/sections/health-shots/2014/10/10/354627818/32-myths-about-the-flu-vaccine-you-dont-need-to-fear

  Flu vaccines effectively reduce the risk of flu for children ages 6 months and up. […] Flu vaccines reduce the risk of pneumonia and other respiratory illnesses or complications from the flu. […] Flu shots reduce the risk of heart attacks, strokes and other cardiovascular events. […] Flu vaccines have been found safe for children 6 months and older. […] A European vaccine against the swine flu in 2009 was linked to narcolepsy, but the U.S. seasonal flu vaccine does not cause narcolepsy. […] The flu vaccine prepares your immune system to fight influenza by stimulating antibody production. […] Only the 1976 swine flu vaccine was linked to Guillain-Barr syndrome, and influenza is more likely to cause the nerve disorder than the flu vaccine; the CDC says those with the Guillain-Barr should consult a doctor before getting the flu shot.

• #48

  https://myhealth.alberta.ca/Health/Pages/conditions.aspx?hwid=tb1913

  Most people get better from influenza (flu) without problems, but the flu can be deadly. It can lead to serious health problems such as pneumonia, or it can make an existing disease worse. Every year, thousands of people end up in the hospital with other health problems from the flu. […] A flu vaccine may not always keep you from getting the seasonal flu, but it can make the symptoms milder and lower the risk of other health problems from the flu. […] The Public Health Agency of Canada (PHAC) recommends that everyone age 6 months and older should get a flu vaccine. But it’s most important to get one if you’re at high risk for other health problems from the flu. Those at high risk include young children, pregnant women, older adults, people who have chronic diseases or weak immune systems, people who live in nursing homes or long term care centres, and indigenous people. […] A flu vaccine is especially important for people who are at high risk for getting other health problems from the flu. […] It’s important that people with chronic diseases or a weak immune system get the flu vaccine each year, because they are at high risk for other health problems from the flu.

• #49

  https://www.who.int/news-room/fact-sheets/detail/influenza-(seasonal)

  Seasonal influenza (the flu) is an acute respiratory infection caused by influenza viruses. […] Vaccination is the best way to prevent the disease. […] Most people will recover from influenza on their own. […] Vaccination is the best way to prevent influenza. […] Safe and effective vaccines have been used for more than 60 years. […] Immunity from vaccination goes away over time so annual vaccination is recommended to protect against influenza. […] The vaccine may be less effective in older people, but it will make the illness less severe and reduces the chance of complications and death. […] Vaccination is especially important for people at high risk of influenza complications and their carers. […] Vaccines are updated routinely with new vaccines developed that contain viruses that match those circulating.

• #50

  https://www.gov.uk/government/publications/flu-vaccination-who-should-have-it-this-winter-and-why/the-flu-vaccination-who-should-have-it-and-why-winter-2023-to-2024

  Flu is caused by influenza viruses that infect the windpipe and lungs. […] Flu vaccines help protect against the main types of flu virus circulating. […] Flu vaccination provides the best protection. […] The strains that are most likely to cause illness are identified in advance of the flu season. […] Flu infection increases the chances of pregnant women and their babies needing intensive care. […] All pregnant women should have a flu vaccine to protect themselves and their babies. […] Flu vaccines do not work well in babies under 6 months of age so it is not recommended. […] The effectiveness of flu vaccination will vary from year to year, depending on the match between the strain of flu in circulation and that contained in the vaccines.

• #51 Flu vaccine | Vaccine Knowledge Project

  https://vaccineknowledge.ox.ac.uk/flu-vaccine

  A 2019 study with 20,000 pregnant women over six years in the United States, Australia, Israel, and Canada, showed that the flu vaccine provided a 40% reduction in hospitalisations from flu. […] The flu vaccine works better in some years than others. […] The flu vaccine prevents between 15 to 52% of flu cases between 2015 – 2020. […] To address this problem of lower effectiveness in older people, an inactivated vaccine containing an adjuvant was introduced for the 2018-19 season. […] It is not understood why flu vaccines do not work so well in older adults. […] Having a flu vaccine every year is important because the flu virus is variable and changes over time. […] Vaccination from previous years is not likely to protect people against current strains of flu. […] Researchers are investigating ways to create a flu vaccine that protects against the many different varieties of flu.

• #52 Flu Shot Frequently Asked Questions | Atrium Health Wake Forest Baptist

  https://www.wakehealth.edu/condition/f/flu/flu-shot-faq

  Everyone, age 6 months and older, is strongly encouraged to be vaccinated annually against the flu virus. […] Vaccination is the best protection against the flu. […] The Centers for Disease Control and Prevention recommends a yearly flu vaccine as the first and most important step in protecting against flu viruses. […] Immunity to flu from the vaccine decreases with time and should be boosted with a yearly shot. […] No, the vaccine cannot cause the flu. […] Flu vaccination provides protection against the influenza strains contained in the seasonal vaccine for the entire season. […] Pregnant women are at high risk of complications from the flu if they become ill during their pregnancy and breastfeeding mothers should be vaccinated to avoid passing the flu to their babies. […] If you have a chronic medical condition it is even more important that you receive the flu vaccine to protect you from the complications of severe influenza infection.

• #53 Seasonal flu vaccine induces antibodies that protect against H7N9 avian flu – UChicago Medicine

  https://www.uchicagomedicine.org/forefront/news/2015/february/seasonal-flu-vaccine-induces-antibodies-that-protect-against-h7n9-avian-flu

  Antibodies that protect against H7N9 avian flu, which emerged in China in 2013 and sparked fears of a global pandemic, have been isolated in individuals who received seasonal flu vaccinations. […] „We have clear evidence that a normal immune response to flu vaccination offers protection against dangerous and highly unique strains of influenza such as H7N9,” said co-senior author Patrick Wilson, PhD, associate professor of medicine at the University of Chicago. […] „It appears more common than previously thought for antibodies induced by flu vaccination to offer cross-protection against H7N9,” said study author Carole Henry, PhD, postdoctoral fellow at the University of Chicago. […] „The challenge is to exploit this response on a larger scale to make vaccines or therapeutics that offer broad protection against influenza strains,” Wilson said. „For now, it’s clear that seasonal flu vaccination provides defense against more than just common strains. Everyone should be vaccinated.”

• #54 Influenza vaccine – Wikipedia

  https://en.wikipedia.org/wiki/Influenza_vaccine

  A 2012 meta-analysis found that flu vaccination was effective 67 percent of the time; the populations that benefited the most were HIV-positive adults aged 18 to 55 (76 percent), healthy adults aged 18 to 46 (approximately 70 percent), and healthy children aged six months to 24 months (66 percent). […] The influenza vaccine also appears to protect against myocardial infarction with a benefit of 15-45%. […] The effectiveness of seasonal flu vaccines varies significantly, with an estimated average efficacy of 50-60% against symptomatic disease, depending on vaccine strain, age, prior immunity, and immune function, so vaccinated people can still contract influenza. […] The effectiveness of flu vaccines is considered to be suboptimal, particularly among the elderly, but vaccination is still beneficial in reducing the mortality rate and hospitalization rate due to influenza as well as duration of hospitalization.

• #55 Influenza vaccine – Wikipedia

  https://en.wikipedia.org/wiki/Influenza_vaccine

  There is not enough evidence to establish significant differences in the effectiveness of different influenza vaccine types, but there are high-dose or adjuvanted products that induce a stronger immune response in the elderly. […] According to a 2016 study by faculty at the University of New South Wales, getting a flu shot was as effective or better at preventing a heart attack than even quitting smoking. […] A 2024 CDC study found that the 2024 flu vaccine reduced the risk of hospitalization from the flu by 35% in the Southern Hemisphere.

• #56 Immunization Safety Review: Influenza Vaccines and Neurological Complications – Immunization Safety Review – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK222009/

  The committee supports ongoing research aimed at better understanding the pathogenesis of influenza and encourages efforts to anticipate which strains might be more neurologically active. […] The committee recommends continued research efforts aimed at identifying genetic variability in human immune system responsiveness as a way to gain a better understanding of genetic susceptibility to vaccine-based adverse events. […] The committee recommends that research be supported to conduct investigations that would deepen and expand the knowledge available from existing studies and more effectively organize what is currently known from these and future projects. […] The committee concludes that the evidence is inadequate to accept or reject a causal relationship between influenza vaccines and incident MS in adults.

• #57 Flu Vaccine (Flu Shot) Side Effects, Effectiveness, When to Get It, Ingredients

  https://www.medicinenet.com/flu_vaccination/article.htm

  Flu vaccination does not protect against infection caused by microbes other than the influenza virus. […] Each year, composition of the influenza viruses changes, making the vaccine used in previous years ineffective. […] The key is to be able to predict which influenza viruses are going to cause infection and to prepare a vaccine against those viruses. […] The flu vaccines stimulate the immune system to produce of antibodies in the body that fight the particular flu virus in the vaccination.

• #58 Flu vaccine | Vaccine Knowledge Project

  https://vaccineknowledge.ox.ac.uk/flu-vaccine

  A 2019 study with 20,000 pregnant women over six years in the United States, Australia, Israel, and Canada, showed that the flu vaccine provided a 40% reduction in hospitalisations from flu. […] The flu vaccine works better in some years than others. […] The flu vaccine prevents between 15 to 52% of flu cases between 2015 – 2020. […] To address this problem of lower effectiveness in older people, an inactivated vaccine containing an adjuvant was introduced for the 2018-19 season. […] It is not understood why flu vaccines do not work so well in older adults. […] Having a flu vaccine every year is important because the flu virus is variable and changes over time. […] Vaccination from previous years is not likely to protect people against current strains of flu. […] Researchers are investigating ways to create a flu vaccine that protects against the many different varieties of flu.

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