Materiały źródłowe

• #1 Epidemiology of delayed ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5002002/

  A large body of literature on diminished ejaculatory disorders has been generated without the use of a clear diagnostic definition. […] Delayed ejaculation (DE) is one of the diminished ejaculatory disorders, which range from varying delays in ejaculatory latency to a complete inability to ejaculate. […] The present review provides an overview of the current knowledge on the epidemiology of diminished ejaculatory disorders, with a focus on the acquired disease in specific populations at higher risk of developing DE and other forms of ejaculatory disorders. […] The lack of a consistent definition of DE and variations in the research methodology accounts for the different prevalence rates reported. […] There seems to be a general agreement that the prevalence of DE is low and ranges from 1% (lifelong DE) to 4% (acquired DE) of sexually active men.

• #2 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/html

  A large body of literature on diminished ejaculatory disorders has been generated without the use of a clear diagnostic definition. […] The present review provides an overview of the current knowledge on the epidemiology of diminished ejaculatory disorders, with a focus on the acquired disease in specific populations at higher risk of developing DE and other forms of ejaculatory disorders. […] The lack of a consistent definition of DE and variations in the research methodology accounts for the different prevalence rates reported. […] There seems to be a general agreement that the prevalence of DE is low and ranges from 1% (lifelong DE) to 4% (acquired DE) of sexually active men. […] However, contrary to old reported percentages, more recent population surveys and cross-sectional observations have reported that, like erectile dysfunction (ED) and premature ejaculation (PE), DE and other diminished ejaculatory dysfunctions are common forms of male sexual dysfunction.

• #3 Ejaculation Problems – Psychologist Sexologist Warsaw

  https://poradnia-harmonia.pl/en/ejaculation-problems/

  Ejaculation problems and erection problems are the most common sexual problems in men. However, while the invention of Viagra significantly facilitated the management of erectile dysfunction, ejaculation problems are still as common as before. […] Ejaculation problems are very common. They can happen to almost any man. Sometimes they can result from one-time indisposition, but if they begin to recur, then it you shoul visit a specialist.

• #4 Orgasmic and ejaculatory problems in clinical practice

  https://www.pulsus.com/scholarly-articles/orgasmic-and-ejaculatory-problems-in-clinical-practice.html

  While erectile dysfunction (ED) is the sexual disorder that most often brings men into the physicians office, ejaculatory and orgasmic concerns are an overlooked and under-reported area of male sexual functioning. Of reported sexual problems, the prevalence of ejaculatory and/or orgasmic disorders approaches 40%, with premature ejaculation being the most common disorder. […] Most men present to a primary care practice with sexual, versus more medical or organic, complaints related to their ejaculatory or orgasmic function. In general, younger men complain of fast or premature ejaculation, whereas older men present with delayed (or the inability to reach) ejaculation. […] It has been stated that only 2% of men who presented for treatment of subfertility were diagnosed with ejaculatory dysfunction as the cause of the subfertility.

• #5 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/html

  Specifically, the above studies have reported that certain demographic and clinical factors correlate with ejaculatory dysfunctions. […] DE appears to be positively related to age and the prevalence differs among races. […] The true incidence of RE is also difficult to estimate. […] Anejaculation occurs in 0.14% of the general population, according to Kinsey. […] The prevalence of DE appears to be moderately and positively related to age, which is not surprising in view of the fact that ejaculatory function as a whole tends to diminish as men age. […] The Global Study of Sexual Attitudes and Behaviours (GSSAB) was an international survey involving 13,882 women and 13,618 men, aged 40-80 years, in order to systematically study factors that may contribute to the aetiology of sexual problems.

• #6 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/html

  An age-dependent increase in the prevalence of DE was reported in an Italian study in which patients with DE were older than those reporting PE. […] High scores (i.e., shorter IELT) progressively decreased as a function of age, suggesting that in advanced age more men complain of DE than of PE. […] Advancing age and increasing comorbidities were associated with greater prevalence rates of ejaculatory dysfunctions. […] Overall, about half of the subjects were overweight and more than 50% of them reported one or more morbidities (hypertension, obesity and heart diseases). […] Around 6% of men reported severe orgasmic impairment that was closely associated with age and concomitant morbidities. […] The prevalence of sexual dysfunction is quite high and tends to increase with age, especially in men.

• #7 Premature Ejaculation: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/435884-overview

  An estimated 30%-70% of American males experience premature ejaculation. The National Health and Social Life Survey (NHSLS) indicates a prevalence of 30%, which is fairly steady through all adult age categories. […] However, various surveys have shown that many men do not report premature ejaculation to their physician, possibly because of embarrassment or a feeling that no treatment is available for the problem. Some men might not even perceive premature ejaculation as a medical problem. Such survey data suggest that the percentage of men who experience premature ejaculation at some point in their lives is almost certainly more than the 30% reported in the NHSLS. […] Estimates of premature ejaculation in European countries and India mirror the prevalence in the United States. […] According to the DSM-5, the estimated prevalence of premature (early) ejaculation is highly variable and depends on the definition being employed.

• #8 Premature ejaculation – Wikipedia

  https://en.wikipedia.org/wiki/Premature_ejaculation

  Premature ejaculation is a prevalent sexual dysfunction in males; however, because of the variability in time required to ejaculate and in partners’ desired duration of sex, exact prevalence rates of PE are difficult to determine. […] In the „Sex in America” surveys (1999 and 2008), University of Chicago researchers found that between adolescence and age 59, approximately 30% of men reported having experienced PE at least once during the previous 12 months, whereas about 10 percent reported erectile dysfunction (ED). […] Other studies report PE prevalence ranging from 3 percent to 41 percent of men over 18, but the great majority estimate a prevalence of 20 to 30 percent making PE a very common sex problem. […] Prevalence studies have indicated, however, that rates of PE are relatively constant across age groups.

• #9 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Ejaculation is a complex physiological process that comprises emission and expulsion processes and is mediated by interwoven neurological and hormonal pathways. Any interference with those pathways may cause a wide range of ejaculatory disorders. The spectrum of ejaculation disorders includes premature ejaculation (PE), retarded or delayed ejaculation, anejaculation, painful ejaculation, retrograde ejaculation, anorgasmia and haemospermia. […] Historically, the main problem in assessing the prevalence of PE has been the lack of a universally recognised definition at the time that surveys were conducted. […] A significant proportion of men with ED also experience PE. High levels of performance anxiety related to ED may worsen PE, with a risk of misdiagnosing PE instead of the underlying ED. According to the National Health and Social Life Survey (NHSLS), the prevalence of PE is not affected by age, unlike ED, which increases with age. Premature ejaculation is not affected by marital or income status. However, PE is more common in Black men, Hispanic men, and men from regions where an Islamic background is common and the prevalence may be higher in men with a lower educational level. Other reported risk factors for PE include genetic predisposition, poor overall health status and obesity, prostate inflammation, hyperthyroidism, low prolactin levels, high testosterone levels, vitamin D and B12 deficiency, diabetes, MetS, lack of physical activity, emotional problems and stress, depressive symptoms, and traumatic sexual experiences.

• #10 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/11774

  An age-dependent increase in the prevalence of DE was reported in an Italian study in which patients with DE were older than those reporting PE. […] In the very well conducted European Male Ageing Study (EMAS), advancing age and increasing comorbidities were associated with greater prevalence rates of ejaculatory dysfunctions. […] Consistent with the results of EMAS, the National Social Life, Health, and Aging Project (NSHAP) reported the prevalence of sexual activity, behaviours and problems in a representative group of the US general population of 3,005 adults. […] The present review provides an overview of the current knowledge on the epidemiology of diminished ejaculatory disorders, with a focus on the acquired disease in specific populations at higher risk of developing DE and other forms of ejaculatory disorders.

• #11 Estimating the Prevalence of Sexual Dysfunction Using the New ICD-11 Guidelines (25.09.2020)

  https://di.aerzteblatt.de/int/archive/article/215864/Estimating-the-prevalence-of-sexual-dysfunction-using-the-new-ICD-11-guidelines-results-of-the-first-representative-population-based-German-Health-and-Sexuality-Survey-(GeSiD)

  The reported prevalence of one or more sexual problems, including mild distress, in the previous 12 months was 33.4% in men (95% confidence interval [31.0; 35.9]) and 45.7% in women [43.0; 48.4]. […] Sexual dysfunction causing marked distress, as per the ICD-11 guidelines, was reported by 13.3% [11.6; 15.1] of the sexually active men (most commonly, erectile dysfunction in 6.6% and early ejaculation in 4.5%), and by 17.5% [15.6; 19.6] of the sexually active women (most commonly, hypoactive sexual desire in 6.9% and orgasmic dysfunction in 5.8%). […] The aim of this partial analysis of the German Health and Sexuality Survey (Studie zu Gesundheit und Sexualität in Deutschland, GeSiD) is to estimate for the first time in Germany or anywhere else the prevalence of sexual dysfunction on the basis of the diagnostic guidelines that will come into effect in 2022 and to differentiate these estimates for various age groups. […] Symptoms of dysfunction with early ejaculation were particularly common in the group of sexually active young men, at 8%, and fell with increasing age to 1.9% in the oldest age-group of sexually active men.

• #12 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Ejaculation is a complex physiological process that comprises emission and expulsion processes and is mediated by interwoven neurological and hormonal pathways. Any interference with those pathways may cause a wide range of ejaculatory disorders. The spectrum of ejaculation disorders includes premature ejaculation (PE), retarded or delayed ejaculation, anejaculation, painful ejaculation, retrograde ejaculation, anorgasmia and haemospermia. […] Historically, the main problem in assessing the prevalence of PE has been the lack of a universally recognised definition at the time that surveys were conducted. […] A significant proportion of men with ED also experience PE. High levels of performance anxiety related to ED may worsen PE, with a risk of misdiagnosing PE instead of the underlying ED. According to the National Health and Social Life Survey (NHSLS), the prevalence of PE is not affected by age, unlike ED, which increases with age. Premature ejaculation is not affected by marital or income status. However, PE is more common in Black men, Hispanic men, and men from regions where an Islamic background is common and the prevalence may be higher in men with a lower educational level. Other reported risk factors for PE include genetic predisposition, poor overall health status and obesity, prostate inflammation, hyperthyroidism, low prolactin levels, high testosterone levels, vitamin D and B12 deficiency, diabetes, MetS, lack of physical activity, emotional problems and stress, depressive symptoms, and traumatic sexual experiences.

• #13 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Ejaculation is a complex physiological process that comprises emission and expulsion processes and is mediated by interwoven neurological and hormonal pathways. Any interference with those pathways may cause a wide range of ejaculatory disorders. The spectrum of ejaculation disorders includes premature ejaculation (PE), retarded or delayed ejaculation, anejaculation, painful ejaculation, retrograde ejaculation, anorgasmia and haemospermia. […] Historically, the main problem in assessing the prevalence of PE has been the lack of a universally recognised definition at the time that surveys were conducted. […] A significant proportion of men with ED also experience PE. High levels of performance anxiety related to ED may worsen PE, with a risk of misdiagnosing PE instead of the underlying ED. According to the National Health and Social Life Survey (NHSLS), the prevalence of PE is not affected by age, unlike ED, which increases with age. Premature ejaculation is not affected by marital or income status. However, PE is more common in Black men, Hispanic men, and men from regions where an Islamic background is common and the prevalence may be higher in men with a lower educational level. Other reported risk factors for PE include genetic predisposition, poor overall health status and obesity, prostate inflammation, hyperthyroidism, low prolactin levels, high testosterone levels, vitamin D and B12 deficiency, diabetes, MetS, lack of physical activity, emotional problems and stress, depressive symptoms, and traumatic sexual experiences.

• #14 Epidemiology of delayed ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5002002/

  A large body of literature on diminished ejaculatory disorders has been generated without the use of a clear diagnostic definition. […] Delayed ejaculation (DE) is one of the diminished ejaculatory disorders, which range from varying delays in ejaculatory latency to a complete inability to ejaculate. […] The present review provides an overview of the current knowledge on the epidemiology of diminished ejaculatory disorders, with a focus on the acquired disease in specific populations at higher risk of developing DE and other forms of ejaculatory disorders. […] The lack of a consistent definition of DE and variations in the research methodology accounts for the different prevalence rates reported. […] There seems to be a general agreement that the prevalence of DE is low and ranges from 1% (lifelong DE) to 4% (acquired DE) of sexually active men.

• #15 Delayed Ejaculation: Background, Etiology, Pathophysiology

  https://emedicine.medscape.com/article/2184956-overview

  Epidemiologic research into orgasmic disorders must contend with the challenge of poor objective confirmatory evidence of patients’ subjective reports, the value of which is further limited by the fact that such disorders are highly sensitive topics in most cultures. […] Because of the lack of a precise definition of the condition, the true prevalence of delayed ejaculation (DE) is not well defined. This syndrome is considered to be the least common male sexual complaint, with prevalence ranging from 1% (lifelong DE) to 4% (acquired DE). […] However, current studies report higher rates of DE, raising the question of old reports probably underestimating the rates of DE. […] Epidemiologic research in this field continues to be hindered by issues such as the following: Lack of well-controlled studies, Wide variability of diagnostic criteria and definitions, Lack of objective markers for the diagnostic criteria used for male orgasmic disorder (MOD), Lack of incidence data.

• #16 Epidemiology of delayed ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5002002/

  However, contrary to old reported percentages, more recent population surveys and cross-sectional observations have reported that, like erectile dysfunction (ED) and premature ejaculation (PE), DE and other diminished ejaculatory dysfunctions are common forms of male sexual dysfunction. […] Specifically, the above studies have reported that certain demographic and clinical factors correlate with ejaculatory dysfunctions. For example, DE appears to be positively related to age and the prevalence differs among races. […] The true incidence of RE is also difficult to estimate. It ranges from 0.3% to 2% of patients attending fertility clinics, but it may increase in patients with diabetes. […] Anejaculation occurs in 0.14% of the general population, according to Kinsey. […] The prevalence of DE appears to be moderately and positively related to age, which is not surprising in view of the fact that ejaculatory function as a whole tends to diminish as men age.

• #17 Epidemiology of delayed ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5002002/

  However, contrary to old reported percentages, more recent population surveys and cross-sectional observations have reported that, like erectile dysfunction (ED) and premature ejaculation (PE), DE and other diminished ejaculatory dysfunctions are common forms of male sexual dysfunction. […] Specifically, the above studies have reported that certain demographic and clinical factors correlate with ejaculatory dysfunctions. For example, DE appears to be positively related to age and the prevalence differs among races. […] The true incidence of RE is also difficult to estimate. It ranges from 0.3% to 2% of patients attending fertility clinics, but it may increase in patients with diabetes. […] Anejaculation occurs in 0.14% of the general population, according to Kinsey. […] The prevalence of DE appears to be moderately and positively related to age, which is not surprising in view of the fact that ejaculatory function as a whole tends to diminish as men age.

• #18 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/html

  Specifically, the above studies have reported that certain demographic and clinical factors correlate with ejaculatory dysfunctions. […] DE appears to be positively related to age and the prevalence differs among races. […] The true incidence of RE is also difficult to estimate. […] Anejaculation occurs in 0.14% of the general population, according to Kinsey. […] The prevalence of DE appears to be moderately and positively related to age, which is not surprising in view of the fact that ejaculatory function as a whole tends to diminish as men age. […] The Global Study of Sexual Attitudes and Behaviours (GSSAB) was an international survey involving 13,882 women and 13,618 men, aged 40-80 years, in order to systematically study factors that may contribute to the aetiology of sexual problems.

• #19 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/html

  An age-dependent increase in the prevalence of DE was reported in an Italian study in which patients with DE were older than those reporting PE. […] High scores (i.e., shorter IELT) progressively decreased as a function of age, suggesting that in advanced age more men complain of DE than of PE. […] Advancing age and increasing comorbidities were associated with greater prevalence rates of ejaculatory dysfunctions. […] Overall, about half of the subjects were overweight and more than 50% of them reported one or more morbidities (hypertension, obesity and heart diseases). […] Around 6% of men reported severe orgasmic impairment that was closely associated with age and concomitant morbidities. […] The prevalence of sexual dysfunction is quite high and tends to increase with age, especially in men.

• #20 Delayed Ejaculation: Background, Etiology, Pathophysiology

  https://emedicine.medscape.com/article/2184956-overview

  Consequently, the available epidemiologic evidence is, at best, informative. Further epidemiologic research is needed to derive an accurate estimate of the incidence of orgasmic disorder in men across age periods, races, cultures, relationship status, and countries. […] The Global Study of Sexual Attitudes and Behaviors (GSSAB), which investigated attitudes, behaviors, beliefs, and satisfaction among 27,500 men and women aged 40-80 years, reported 13.2% of men as not reaching orgasm. […] The incidence of DE begins to increase after the age of 50 years. Compared with men younger than 59 years, men in their 80s report twice as much difficulty in ejaculating. […] In a review of 52 studies, the estimated rate of MOD among gay men was 38% (notably higher than from other samples), leading the authors to speculate that this difference might reflect a greater recognition of the threat of infection with HIV. […] Reports of DE vary across countries and cultures. In general, this complaint is more commonly reported by men in Asian populations than by men living in the United States, Australia, or Europe. Such variation may be due to cultural or genetic differences.

• #21 Epidemiology of delayed ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5002002/

  However, contrary to old reported percentages, more recent population surveys and cross-sectional observations have reported that, like erectile dysfunction (ED) and premature ejaculation (PE), DE and other diminished ejaculatory dysfunctions are common forms of male sexual dysfunction. […] Specifically, the above studies have reported that certain demographic and clinical factors correlate with ejaculatory dysfunctions. For example, DE appears to be positively related to age and the prevalence differs among races. […] The true incidence of RE is also difficult to estimate. It ranges from 0.3% to 2% of patients attending fertility clinics, but it may increase in patients with diabetes. […] Anejaculation occurs in 0.14% of the general population, according to Kinsey. […] The prevalence of DE appears to be moderately and positively related to age, which is not surprising in view of the fact that ejaculatory function as a whole tends to diminish as men age.

• #22 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/html

  Specifically, the above studies have reported that certain demographic and clinical factors correlate with ejaculatory dysfunctions. […] DE appears to be positively related to age and the prevalence differs among races. […] The true incidence of RE is also difficult to estimate. […] Anejaculation occurs in 0.14% of the general population, according to Kinsey. […] The prevalence of DE appears to be moderately and positively related to age, which is not surprising in view of the fact that ejaculatory function as a whole tends to diminish as men age. […] The Global Study of Sexual Attitudes and Behaviours (GSSAB) was an international survey involving 13,882 women and 13,618 men, aged 40-80 years, in order to systematically study factors that may contribute to the aetiology of sexual problems.

• #23 Epidemiology of delayed ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5002002/

  However, contrary to old reported percentages, more recent population surveys and cross-sectional observations have reported that, like erectile dysfunction (ED) and premature ejaculation (PE), DE and other diminished ejaculatory dysfunctions are common forms of male sexual dysfunction. […] Specifically, the above studies have reported that certain demographic and clinical factors correlate with ejaculatory dysfunctions. For example, DE appears to be positively related to age and the prevalence differs among races. […] The true incidence of RE is also difficult to estimate. It ranges from 0.3% to 2% of patients attending fertility clinics, but it may increase in patients with diabetes. […] Anejaculation occurs in 0.14% of the general population, according to Kinsey. […] The prevalence of DE appears to be moderately and positively related to age, which is not surprising in view of the fact that ejaculatory function as a whole tends to diminish as men age.

• #24 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Painful ejaculation is a condition in which a patient feels mild discomfort to severe pain during or after ejaculation. The pain can involve the penis, scrotum, and perineum. […] Retrograde ejaculation is the total, or sometimes partial, absence of antegrade ejaculation, due to semen passing backwards through the bladder neck into the bladder. Patients may experience a normal or decreased orgasmic sensation. The causes of retrograde ejaculation can be divided into neurogenic, pharmacological, urethral, or bladder neck incompetence. […] Haemospermia is defined as the appearance of blood in the ejaculate. Although it is often regarded as a symptom of minor significance, blood in the ejaculate causes anxiety in many men and may indicate underlying pathology.

• #25 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Painful ejaculation is a condition in which a patient feels mild discomfort to severe pain during or after ejaculation. The pain can involve the penis, scrotum, and perineum. […] Retrograde ejaculation is the total, or sometimes partial, absence of antegrade ejaculation, due to semen passing backwards through the bladder neck into the bladder. Patients may experience a normal or decreased orgasmic sensation. The causes of retrograde ejaculation can be divided into neurogenic, pharmacological, urethral, or bladder neck incompetence. […] Haemospermia is defined as the appearance of blood in the ejaculate. Although it is often regarded as a symptom of minor significance, blood in the ejaculate causes anxiety in many men and may indicate underlying pathology.

• #26 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/html

  An age-dependent increase in the prevalence of DE was reported in an Italian study in which patients with DE were older than those reporting PE. […] High scores (i.e., shorter IELT) progressively decreased as a function of age, suggesting that in advanced age more men complain of DE than of PE. […] Advancing age and increasing comorbidities were associated with greater prevalence rates of ejaculatory dysfunctions. […] Overall, about half of the subjects were overweight and more than 50% of them reported one or more morbidities (hypertension, obesity and heart diseases). […] Around 6% of men reported severe orgasmic impairment that was closely associated with age and concomitant morbidities. […] The prevalence of sexual dysfunction is quite high and tends to increase with age, especially in men.

• #27 Premature Ejaculation: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/435884-overview

  Although more than 20-30% of men aged 8-70 years report being concerned about the rapidity of their ejaculation, only 1-3% would be classified as having premature (early) ejaculation according to the current DSM-5 criteria (ie, ejaculation occurring within 1 minute after intromission and before the individual wishes). […] Premature ejaculation can occur at virtually any age in an adult man’s life. As a reported condition, it is most common in men aged 18-30 years but may also occur in conjunction with secondary impotence in men aged 45-65 years. […] At present, there are no reproducible data indicating major differences between racial groups with respect to the incidence or prevalence of premature ejaculation. However, a few surveys suggest that some degree of racial variation may exist.

• #28 Estimating the Prevalence of Sexual Dysfunction Using the New ICD-11 Guidelines (25.09.2020)

  https://di.aerzteblatt.de/int/archive/article/215864/Estimating-the-prevalence-of-sexual-dysfunction-using-the-new-ICD-11-guidelines-results-of-the-first-representative-population-based-German-Health-and-Sexuality-Survey-(GeSiD)

  The reported prevalence of one or more sexual problems, including mild distress, in the previous 12 months was 33.4% in men (95% confidence interval [31.0; 35.9]) and 45.7% in women [43.0; 48.4]. […] Sexual dysfunction causing marked distress, as per the ICD-11 guidelines, was reported by 13.3% [11.6; 15.1] of the sexually active men (most commonly, erectile dysfunction in 6.6% and early ejaculation in 4.5%), and by 17.5% [15.6; 19.6] of the sexually active women (most commonly, hypoactive sexual desire in 6.9% and orgasmic dysfunction in 5.8%). […] The aim of this partial analysis of the German Health and Sexuality Survey (Studie zu Gesundheit und Sexualität in Deutschland, GeSiD) is to estimate for the first time in Germany or anywhere else the prevalence of sexual dysfunction on the basis of the diagnostic guidelines that will come into effect in 2022 and to differentiate these estimates for various age groups. […] Symptoms of dysfunction with early ejaculation were particularly common in the group of sexually active young men, at 8%, and fell with increasing age to 1.9% in the oldest age-group of sexually active men.

• #29 Epidemiology of delayed ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5002002/

  The present review provides an overview of the current knowledge on the epidemiology of diminished ejaculatory disorders, with a focus on the acquired disease in specific populations at higher risk of developing DE and other forms of ejaculatory disorders. […] Ejaculatory dysfunctions in the aged male are most probably due to several comorbidities, including metabolic and cardiovascular disorders, increased prevalence of T deficiency, increased use of medications, and decreased exercise. […] These data highlight that during the entire lifespan, but in particular in old age, sexual issues should be adequately addressed by investigating illnesses that might contribute to sexual problems.

• #30 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/html

  These data highlight that during the entire lifespan, but in particular in old age, sexual issues should be adequately addressed by investigating illnesses that might contribute to sexual problems. […] After adjusting for age and common comorbidities, ejaculatory dysfunctions were significantly associated with LUTS and men with severe LUTS were 3.3 times more likely to report ejaculation disorders. […] This has a significant negative impact on quality of life, not only in regard to orgasmic function, but also for fertility, considering the relatively early onset of BPH.

• #31 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/11774

  After adjusting for age and common comorbidities, ejaculatory dysfunctions were significantly associated with LUTS and men with severe LUTS were 3.3 times more likely to report ejaculation disorders. […] These data highlight that during the entire lifespan, but in particular in old age, sexual issues should be adequately addressed by investigating illnesses that might contribute to sexual problems.

• #32 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/html

  These data highlight that during the entire lifespan, but in particular in old age, sexual issues should be adequately addressed by investigating illnesses that might contribute to sexual problems. […] After adjusting for age and common comorbidities, ejaculatory dysfunctions were significantly associated with LUTS and men with severe LUTS were 3.3 times more likely to report ejaculation disorders. […] This has a significant negative impact on quality of life, not only in regard to orgasmic function, but also for fertility, considering the relatively early onset of BPH.

• #33 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Men with PE are more likely to report low satisfaction with their sexual relationship, low satisfaction with sexual intercourse, difficulty relaxing during intercourse, and less-frequent intercourse. Premature ejaculation can have a detrimental effect on self-confidence and the relationship with the partner, and may sometimes cause mental distress, anxiety, embarrassment and depression. Moreover, PE may also affect the partners sexual functioning and their satisfaction with the sexual relationship decreases with increasing severity of the patients condition. Despite the possible serious psychological and QoL consequences of PE, few men seek treatment. […] There is still little consensus about the definition and classification of PE. It is now universally accepted that premature ejaculation is a broad term that includes several concepts belonging to the common category of PE. The most recent definition comes from the International Classification of Diseases 11th Revision, where PE was renamed as Early Ejaculation: Male early ejaculation is characterized by ejaculation that occurs prior to or within a very short duration of the initiation of vaginal penetration or other relevant sexual stimulation, with no or little perceived control over ejaculation. The pattern of early ejaculation has occurred episodically or persistently over a period of at least several months and is associated with clinically significant distress.

• #34 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Dapoxetine is the first on-demand oral pharmacological agent approved for lifelong and acquired PE in many countries, except for the USA. The metered-dose aerosol spray of lidocaine and prilocaine combination is the first topical formulation to be officially approved for on-demand treatment of lifelong PE by the EMA in the European Union. All other medications used in PE are off-label indications. […] The need to objectively assess PE has led to the development of several questionnaires based on using PROMs. Only two questionnaires can discriminate between patients who have PE and those who do not: Premature Ejaculation Diagnostic Tool (PEDT) and Arabic Index of Premature Ejaculation (AIPE). […] There is scarce literature on the psychological aspects relating to DE, as well as on empirical evidence regarding psychological treatment efficacy. Studies on psychological aspects have revealed that men with DE show a strong need to control their sexual experiences. Delayed ejaculation is associated with difficulties surrendering to sexual pleasure during sex – i.e., the sense of letting go – which denotes an underlying psychological mechanism influencing the reaching of orgasm.

• #35

  https://journals.lww.com/md-journal/fulltext/2016/08300/relationship_between_premature_ejaculation_and.39.aspx

  Premature ejaculation (PE) is the most prevalent male sexual dysfunction. Epidemiologic findings are inconsistent concerning the risk for depression associated with PE. […] Eight trials involving 18,035 patients were included in the meta-analysis. Depression were statistically significantly associated with the risk of PE (OR = 1.63, 95% CI:1.421.87). […] These findings provide evidence that depression is associated with a significantly increased risk of PE. […] In our systematic review, we included 8 trials that met the quality criteria of patient selection. The present meta-analysis firstly evaluated available data on the relationship between depression and PE and showed that depression is associated with a significantly increased risk of PE. […] Given that PE is prevalent worldwide, the findings of our meta-analysis have important implications for the evaluation and treatment of patients with PE. […] In conclusion, this meta-analysis of observational studies suggests that depression is significantly associated with an increased risk of PE. Prevention and treatment of depression may substantially decrease the risk of PE.

• #36 Delayed Ejaculation: Background, Etiology, Pathophysiology

  https://emedicine.medscape.com/article/2184956-overview

  Consequently, the available epidemiologic evidence is, at best, informative. Further epidemiologic research is needed to derive an accurate estimate of the incidence of orgasmic disorder in men across age periods, races, cultures, relationship status, and countries. […] The Global Study of Sexual Attitudes and Behaviors (GSSAB), which investigated attitudes, behaviors, beliefs, and satisfaction among 27,500 men and women aged 40-80 years, reported 13.2% of men as not reaching orgasm. […] The incidence of DE begins to increase after the age of 50 years. Compared with men younger than 59 years, men in their 80s report twice as much difficulty in ejaculating. […] In a review of 52 studies, the estimated rate of MOD among gay men was 38% (notably higher than from other samples), leading the authors to speculate that this difference might reflect a greater recognition of the threat of infection with HIV. […] Reports of DE vary across countries and cultures. In general, this complaint is more commonly reported by men in Asian populations than by men living in the United States, Australia, or Europe. Such variation may be due to cultural or genetic differences.

• #37 Delayed Ejaculation: Background, Etiology, Pathophysiology

  https://emedicine.medscape.com/article/2184956-overview

  Consequently, the available epidemiologic evidence is, at best, informative. Further epidemiologic research is needed to derive an accurate estimate of the incidence of orgasmic disorder in men across age periods, races, cultures, relationship status, and countries. […] The Global Study of Sexual Attitudes and Behaviors (GSSAB), which investigated attitudes, behaviors, beliefs, and satisfaction among 27,500 men and women aged 40-80 years, reported 13.2% of men as not reaching orgasm. […] The incidence of DE begins to increase after the age of 50 years. Compared with men younger than 59 years, men in their 80s report twice as much difficulty in ejaculating. […] In a review of 52 studies, the estimated rate of MOD among gay men was 38% (notably higher than from other samples), leading the authors to speculate that this difference might reflect a greater recognition of the threat of infection with HIV. […] Reports of DE vary across countries and cultures. In general, this complaint is more commonly reported by men in Asian populations than by men living in the United States, Australia, or Europe. Such variation may be due to cultural or genetic differences.

• #38 Evolving Diagnosis and Management of Ejaculatory Disorders: A Focus on Premature Ejaculation

  https://www.medscape.org/viewarticle/508092

  This is a study, reported in Urology in 2004, showing the prevalence of PE in 7 different regions of the world. With the exception of the Middle East, which is 12%, the prevalence of PE in all of the other regions was from 20% to 30%; it’s remarkably consistent worldwide. […] A partial summary at this point is that normal ejaculatory latency times can vary widely, although less than 3 minutes is common for men with PE. There are various definitions of PE, but most of the definitions refer to the ejaculatory latency time, control issues, and sexual satisfaction. PE prevalence is consistent at about 30% across all ages. The etiology is multifactorial, but a neurobiologic basis is being increasingly acknowledged. There may be comorbidities and risk factors including, particularly, erectile dysfunction.

• #39 Urology » Delayed ejaculation: epidemiology, diagnostics and treatment

  https://urologyjournal.ru/en/archive/article/38475

  Delayed ejaculation is a form of sexual disorders, which is characterized by constant or intermittent delays or absence of ejaculation and orgasm, despite normal sexual arousal and erectile function. […] Current views on epidemiology, diagnostics and treatment strategy of delayed ejaculation are presented in the article. […] Delayed ejaculation is one of the most studied and rare types of male sexual dysfunctions, which leads to depression, anxiety, and often is a reason of low self-esteem, reduced satisfaction of a man with his partner, and worsening of relationships between partners. […] In some cases, delayed ejaculation and anejaculation cause infertility.

• #40 Disorders of Ejaculation: An AUA/SMSNA Guideline (2020) – American Urological Association

  https://www.auanet.org/guidelines-and-quality/guidelines/disorders-of-ejaculation

  The act of ejaculation has important connotations for many men, aside from its association with orgasmic pleasure and necessity for procreation. […] Ejaculation may be of greater priority in men who have sex with men (MSM). […] Disorders of the timing of ejaculation can pose a major impediment to sexual satisfaction for both men and their partners. […] The sexual response cycle in men is conceptualized as a linear process of increasing sexual excitement, starting with desire and followed by arousal, climax, and resolution. […] Ejaculation is triggered by integration of tactile and non-tactile stimuli in the brain. […] Ejaculatory dysfunction is increasingly common with age, which is itself associated with declining serum T levels. […] The majority of these drugs are not commonly utilized in urological practice; the urologist who is not comfortable prescribing these medications should consider referral of the patient for discussion of these management options.

• #41 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Men with PE are more likely to report low satisfaction with their sexual relationship, low satisfaction with sexual intercourse, difficulty relaxing during intercourse, and less-frequent intercourse. Premature ejaculation can have a detrimental effect on self-confidence and the relationship with the partner, and may sometimes cause mental distress, anxiety, embarrassment and depression. Moreover, PE may also affect the partners sexual functioning and their satisfaction with the sexual relationship decreases with increasing severity of the patients condition. Despite the possible serious psychological and QoL consequences of PE, few men seek treatment. […] There is still little consensus about the definition and classification of PE. It is now universally accepted that premature ejaculation is a broad term that includes several concepts belonging to the common category of PE. The most recent definition comes from the International Classification of Diseases 11th Revision, where PE was renamed as Early Ejaculation: Male early ejaculation is characterized by ejaculation that occurs prior to or within a very short duration of the initiation of vaginal penetration or other relevant sexual stimulation, with no or little perceived control over ejaculation. The pattern of early ejaculation has occurred episodically or persistently over a period of at least several months and is associated with clinically significant distress.

• #42 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Men with PE are more likely to report low satisfaction with their sexual relationship, low satisfaction with sexual intercourse, difficulty relaxing during intercourse, and less-frequent intercourse. Premature ejaculation can have a detrimental effect on self-confidence and the relationship with the partner, and may sometimes cause mental distress, anxiety, embarrassment and depression. Moreover, PE may also affect the partners sexual functioning and their satisfaction with the sexual relationship decreases with increasing severity of the patients condition. Despite the possible serious psychological and QoL consequences of PE, few men seek treatment. […] There is still little consensus about the definition and classification of PE. It is now universally accepted that premature ejaculation is a broad term that includes several concepts belonging to the common category of PE. The most recent definition comes from the International Classification of Diseases 11th Revision, where PE was renamed as Early Ejaculation: Male early ejaculation is characterized by ejaculation that occurs prior to or within a very short duration of the initiation of vaginal penetration or other relevant sexual stimulation, with no or little perceived control over ejaculation. The pattern of early ejaculation has occurred episodically or persistently over a period of at least several months and is associated with clinically significant distress.

• #43 KoreaMed Synapse

  https://synapse.koreamed.org/articles/1088855

  Delayed ejaculation (DE) is a poorly defined and uncommon form of male sexual dysfunction, characterized by a marked delay in ejaculation or an inability to achieve ejaculation. […] The literature suggests that the pathophysiology of DE/AE is multifactorial, including both organic and psychosocial factors. […] There is currently no single gold standard for diagnosing DE/AE, as operationalized criteria do not exist. […] The prevalence rate of DE among the general population ranges from 1% of sexually active men (lifelong DE) to 5% (acquired DE). […] Despite the many publications on this condition, the exact pathogenesis is not yet known. […] The history is the key to the diagnosis. […] Treatment should be cause-specific. […] A number of approaches can be employed for infertile men, including collection of nocturnal emissions, prostatic massage, prostatic urethra catheterization, penile vibratory stimulation, probe electroejaculation, sperm retrieval by aspiration from either the vas deferens or the epididymis, and testicular sperm extraction.

• #44 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Diagnosis of PE is based on the patients medical and sexual history. History should classify PE as lifelong or acquired and determine whether PE is situational (under specific circumstances or with a specific partner) or consistent. Special attention should be given to the duration time of ejaculation, degree of sexual stimulus, impact on sexual activity and QoL, and drug use or abuse. It is also important to distinguish PE from ED. Many patients with ED develop secondary PE caused by the anxiety associated with difficulty in attaining and maintaining an erection. […] Before commencing any treatment, it is essential to define the subtype of PE and discuss patients expectations thoroughly. Pharmacotherapy must be considered the first-line treatment for patients with lifelong PE, whereas treating the underlying cause (e.g., ED, prostatitis, LUTS, anxiety and hyperthyroidism) must be the initial goal for patients with acquired PE.

• #45 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Dapoxetine is the first on-demand oral pharmacological agent approved for lifelong and acquired PE in many countries, except for the USA. The metered-dose aerosol spray of lidocaine and prilocaine combination is the first topical formulation to be officially approved for on-demand treatment of lifelong PE by the EMA in the European Union. All other medications used in PE are off-label indications. […] The need to objectively assess PE has led to the development of several questionnaires based on using PROMs. Only two questionnaires can discriminate between patients who have PE and those who do not: Premature Ejaculation Diagnostic Tool (PEDT) and Arabic Index of Premature Ejaculation (AIPE). […] There is scarce literature on the psychological aspects relating to DE, as well as on empirical evidence regarding psychological treatment efficacy. Studies on psychological aspects have revealed that men with DE show a strong need to control their sexual experiences. Delayed ejaculation is associated with difficulties surrendering to sexual pleasure during sex – i.e., the sense of letting go – which denotes an underlying psychological mechanism influencing the reaching of orgasm.

• #46 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Several pharmacological agents, including cabergoline, bupropion, alpha-1-adrenergic agonists, buspirone, oxytocin, testosterone, bethanechol, yohimbine, amantadine, cyproheptadine and apomorphine have been used to treat DE with varied success. Unfortunately, there is no FDA or EMA-approved medications to treat DE, as most of the cited research is based on case-cohort studies that were not randomised, blinded, or placebo-controlled. […] Anejaculation involves the complete absence of antegrade or retrograde ejaculation. It is caused by the failure of semen emission from the seminal vesicles, prostate, and ejaculatory ducts into the urethra. True anejaculation is usually associated with a normal orgasmic sensation and is always associated with central or peripheral nervous system dysfunction or with drugs.

• #47 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Ejaculation is a complex physiological process that comprises emission and expulsion processes and is mediated by interwoven neurological and hormonal pathways. Any interference with those pathways may cause a wide range of ejaculatory disorders. The spectrum of ejaculation disorders includes premature ejaculation (PE), retarded or delayed ejaculation, anejaculation, painful ejaculation, retrograde ejaculation, anorgasmia and haemospermia. […] Historically, the main problem in assessing the prevalence of PE has been the lack of a universally recognised definition at the time that surveys were conducted. […] A significant proportion of men with ED also experience PE. High levels of performance anxiety related to ED may worsen PE, with a risk of misdiagnosing PE instead of the underlying ED. According to the National Health and Social Life Survey (NHSLS), the prevalence of PE is not affected by age, unlike ED, which increases with age. Premature ejaculation is not affected by marital or income status. However, PE is more common in Black men, Hispanic men, and men from regions where an Islamic background is common and the prevalence may be higher in men with a lower educational level. Other reported risk factors for PE include genetic predisposition, poor overall health status and obesity, prostate inflammation, hyperthyroidism, low prolactin levels, high testosterone levels, vitamin D and B12 deficiency, diabetes, MetS, lack of physical activity, emotional problems and stress, depressive symptoms, and traumatic sexual experiences.

• #48 Disorders of Ejaculation: An AUA/SMSNA Guideline (2020) – American Urological Association

  https://www.auanet.org/guidelines-and-quality/guidelines/disorders-of-ejaculation

  The act of ejaculation has important connotations for many men, aside from its association with orgasmic pleasure and necessity for procreation. […] Ejaculation may be of greater priority in men who have sex with men (MSM). […] Disorders of the timing of ejaculation can pose a major impediment to sexual satisfaction for both men and their partners. […] The sexual response cycle in men is conceptualized as a linear process of increasing sexual excitement, starting with desire and followed by arousal, climax, and resolution. […] Ejaculation is triggered by integration of tactile and non-tactile stimuli in the brain. […] Ejaculatory dysfunction is increasingly common with age, which is itself associated with declining serum T levels. […] The majority of these drugs are not commonly utilized in urological practice; the urologist who is not comfortable prescribing these medications should consider referral of the patient for discussion of these management options.

• #49 Delayed Ejaculation: Background, Etiology, Pathophysiology

  https://emedicine.medscape.com/article/2184956-overview

  Epidemiologic research into orgasmic disorders must contend with the challenge of poor objective confirmatory evidence of patients’ subjective reports, the value of which is further limited by the fact that such disorders are highly sensitive topics in most cultures. […] Because of the lack of a precise definition of the condition, the true prevalence of delayed ejaculation (DE) is not well defined. This syndrome is considered to be the least common male sexual complaint, with prevalence ranging from 1% (lifelong DE) to 4% (acquired DE). […] However, current studies report higher rates of DE, raising the question of old reports probably underestimating the rates of DE. […] Epidemiologic research in this field continues to be hindered by issues such as the following: Lack of well-controlled studies, Wide variability of diagnostic criteria and definitions, Lack of objective markers for the diagnostic criteria used for male orgasmic disorder (MOD), Lack of incidence data.

• #50 Epidemiology of delayed ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5002002/

  A large body of literature on diminished ejaculatory disorders has been generated without the use of a clear diagnostic definition. […] Delayed ejaculation (DE) is one of the diminished ejaculatory disorders, which range from varying delays in ejaculatory latency to a complete inability to ejaculate. […] The present review provides an overview of the current knowledge on the epidemiology of diminished ejaculatory disorders, with a focus on the acquired disease in specific populations at higher risk of developing DE and other forms of ejaculatory disorders. […] The lack of a consistent definition of DE and variations in the research methodology accounts for the different prevalence rates reported. […] There seems to be a general agreement that the prevalence of DE is low and ranges from 1% (lifelong DE) to 4% (acquired DE) of sexually active men.

• #51 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/html

  A large body of literature on diminished ejaculatory disorders has been generated without the use of a clear diagnostic definition. […] The present review provides an overview of the current knowledge on the epidemiology of diminished ejaculatory disorders, with a focus on the acquired disease in specific populations at higher risk of developing DE and other forms of ejaculatory disorders. […] The lack of a consistent definition of DE and variations in the research methodology accounts for the different prevalence rates reported. […] There seems to be a general agreement that the prevalence of DE is low and ranges from 1% (lifelong DE) to 4% (acquired DE) of sexually active men. […] However, contrary to old reported percentages, more recent population surveys and cross-sectional observations have reported that, like erectile dysfunction (ED) and premature ejaculation (PE), DE and other diminished ejaculatory dysfunctions are common forms of male sexual dysfunction.

• #52 Disorders of Ejaculation: An AUA/SMSNA Guideline (2020) – American Urological Association

  https://www.auanet.org/guidelines-and-quality/guidelines/disorders-of-ejaculation

  Both PE and DE are poorly understood and difficult to define. […] Although the reported prevalence of clinical PE and DE is less than 5%, the experience of many clinicians who see patients for sexual problems suggests that these problem are not at all rare. […] The understanding of the neurophysiology of ejaculation and orgasm remains limited. […] A number of novel procedural approaches to BPH have been developed due in part to dissatisfaction with ejaculatory outcomes associated with conventional surgical BPH treatments. […] Ejaculation consists of two distinct phases. […] Normal antegrade ejaculation relies heavily on the normal function of the prostate and bladder neck. […] Medical and surgical interventions that alter function of the prostate and/or bladder neck often have noticeable and bothersome effects on ejaculation.

• #53 Delayed Ejaculation: Background, Etiology, Pathophysiology

  https://emedicine.medscape.com/article/2184956-overview

  Epidemiologic research into orgasmic disorders must contend with the challenge of poor objective confirmatory evidence of patients’ subjective reports, the value of which is further limited by the fact that such disorders are highly sensitive topics in most cultures. […] Because of the lack of a precise definition of the condition, the true prevalence of delayed ejaculation (DE) is not well defined. This syndrome is considered to be the least common male sexual complaint, with prevalence ranging from 1% (lifelong DE) to 4% (acquired DE). […] However, current studies report higher rates of DE, raising the question of old reports probably underestimating the rates of DE. […] Epidemiologic research in this field continues to be hindered by issues such as the following: Lack of well-controlled studies, Wide variability of diagnostic criteria and definitions, Lack of objective markers for the diagnostic criteria used for male orgasmic disorder (MOD), Lack of incidence data.

• #54 Delayed Ejaculation: Background, Etiology, Pathophysiology

  https://emedicine.medscape.com/article/2184956-overview

  Consequently, the available epidemiologic evidence is, at best, informative. Further epidemiologic research is needed to derive an accurate estimate of the incidence of orgasmic disorder in men across age periods, races, cultures, relationship status, and countries. […] The Global Study of Sexual Attitudes and Behaviors (GSSAB), which investigated attitudes, behaviors, beliefs, and satisfaction among 27,500 men and women aged 40-80 years, reported 13.2% of men as not reaching orgasm. […] The incidence of DE begins to increase after the age of 50 years. Compared with men younger than 59 years, men in their 80s report twice as much difficulty in ejaculating. […] In a review of 52 studies, the estimated rate of MOD among gay men was 38% (notably higher than from other samples), leading the authors to speculate that this difference might reflect a greater recognition of the threat of infection with HIV. […] Reports of DE vary across countries and cultures. In general, this complaint is more commonly reported by men in Asian populations than by men living in the United States, Australia, or Europe. Such variation may be due to cultural or genetic differences.

• #55 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Men with PE are more likely to report low satisfaction with their sexual relationship, low satisfaction with sexual intercourse, difficulty relaxing during intercourse, and less-frequent intercourse. Premature ejaculation can have a detrimental effect on self-confidence and the relationship with the partner, and may sometimes cause mental distress, anxiety, embarrassment and depression. Moreover, PE may also affect the partners sexual functioning and their satisfaction with the sexual relationship decreases with increasing severity of the patients condition. Despite the possible serious psychological and QoL consequences of PE, few men seek treatment. […] There is still little consensus about the definition and classification of PE. It is now universally accepted that premature ejaculation is a broad term that includes several concepts belonging to the common category of PE. The most recent definition comes from the International Classification of Diseases 11th Revision, where PE was renamed as Early Ejaculation: Male early ejaculation is characterized by ejaculation that occurs prior to or within a very short duration of the initiation of vaginal penetration or other relevant sexual stimulation, with no or little perceived control over ejaculation. The pattern of early ejaculation has occurred episodically or persistently over a period of at least several months and is associated with clinically significant distress.

• #56 Premature Ejaculation: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/435884-overview

  An estimated 30%-70% of American males experience premature ejaculation. The National Health and Social Life Survey (NHSLS) indicates a prevalence of 30%, which is fairly steady through all adult age categories. […] However, various surveys have shown that many men do not report premature ejaculation to their physician, possibly because of embarrassment or a feeling that no treatment is available for the problem. Some men might not even perceive premature ejaculation as a medical problem. Such survey data suggest that the percentage of men who experience premature ejaculation at some point in their lives is almost certainly more than the 30% reported in the NHSLS. […] Estimates of premature ejaculation in European countries and India mirror the prevalence in the United States. […] According to the DSM-5, the estimated prevalence of premature (early) ejaculation is highly variable and depends on the definition being employed.

• #57 Ejaculation Problems: Too Fast, Too Slow or Not at All? » Sexual Medicine » BUMC

  https://www.bumc.bu.edu/sexualmedicine/informationsessions/ejaculation-problems-too-fast-too-slow-or-not-at-all/

  For men, erectile dysfunction and ejaculatory problems are the most common sexual difficulties. […] Ejaculatory problems continue to be commonplace among men and often create feelings of shame and embarrassment for those men who struggle with this difficulty. […] Typically, ejaculatory disorders fall into two categories. These are: delayed ejaculation and early ejaculation. […] Problems of delayed ejaculation tend to be somewhat rare and not well understood by psychologists and sex therapists. […] In many cases, the man himself may tend to delay treatment or to minimize the distress of the situation. […] Unfortunately however, problems such as delayed ejaculation seldom disappear without professional intervention. […] Ejaculatory problems can have a devastating affect on self-esteem.

• #58 EAU Guidelines on Sexual and Reproductive Health – Uroweb

  https://uroweb.org/guidelines/sexual-and-reproductive-health/chapter/disorders-of-ejaculation

  Dapoxetine is the first on-demand oral pharmacological agent approved for lifelong and acquired PE in many countries, except for the USA. The metered-dose aerosol spray of lidocaine and prilocaine combination is the first topical formulation to be officially approved for on-demand treatment of lifelong PE by the EMA in the European Union. All other medications used in PE are off-label indications. […] The need to objectively assess PE has led to the development of several questionnaires based on using PROMs. Only two questionnaires can discriminate between patients who have PE and those who do not: Premature Ejaculation Diagnostic Tool (PEDT) and Arabic Index of Premature Ejaculation (AIPE). […] There is scarce literature on the psychological aspects relating to DE, as well as on empirical evidence regarding psychological treatment efficacy. Studies on psychological aspects have revealed that men with DE show a strong need to control their sexual experiences. Delayed ejaculation is associated with difficulties surrendering to sexual pleasure during sex – i.e., the sense of letting go – which denotes an underlying psychological mechanism influencing the reaching of orgasm.

• #59 Prevalence of Premature Ejaculation: A Narrative Review of National and Cultural Differences

  https://www.mdpi.com/2411-5118/5/4/43

  The prevalence of premature ejaculation (PE) across different cultures and nationalities has long been a topic of debate, with early studies suggesting that men in such regions as the Middle East and Asia experience higher rates. However, the validity of these claims has been questioned due to methodological inconsistencies and the lack of comparative studies that apply uniform diagnostic criteria across different populations. This narrative review aims to analyze the existing literature to assess whether justifiable support for cultural or national differences regarding PE prevalence truly exists. […] The review found that differences in PE prevalence across cultures are more likely due to methodological variations than true cultural or national differences. While some trends, such as slightly higher rates in Latin American and Asian countries, were noted, no consistent patterns emerged. Studies using standardized methods, like the PEDT, generally showed prevalence rates between 5% and 15%, with no clear outliers across regions. Thus, current evidence does not support significant cultural or national differences in PE prevalence.

• #60 Journal of Medical Internet Research – Online Public Attention Toward Premature Ejaculation in Mainland China: Infodemiology Study Using the Baidu Index

  https://www.jmir.org/2021/8/e30271/

  Premature ejaculation (PE) is one of the most described psychosocial stress and sexual complaints worldwide. The estimated PE prevalence rate is 16% and over 20% in an internet-based survey. The PE prevalence and its actual impact may hence remain unveiled and underestimated. The Baidu Index was queried using the PE-related terms for the period of January 2011 to December 2020. The annual percent change (APC) for the complaint topic was 48.80% (P<.001) for 2011 to 2014 and 16.82% (P<.001) for 2014 to 2020. The age distribution of those searching for topics related to PE showed that the population aged 20 to 40 years comprised nearly 70% of the total search inquiries. The fluctuating online popularity of PE searches reflects the real-time population demands. The PE BSI geographic distribution was calculated based on provincial data and sorted according to Chinese administrative divisions. The PE search popularity was dominated by searches from the East China, North China, and South China regions, where the top four Chinese megacities are located. PE was reported as the most common sexual complaint in males in all age groups in previous epidemiological studies. In our investigation, over 70% of PE online search queries came from males aged 20 to 39 years. The most popular term was "The fastest and easiest way to cure PE?" The relationship between PE and chronic prostatitis (CP) has been long observed. The most queried terms were related to selective serotonin reuptake inhibitors. The fluctuating online popularity of PE searches reflects the real-time population demands. [...] The internet search data could be more reliable when the insufficient and lagging registry data are completed.

• #61 Journal of Medical Internet Research – Online Public Attention Toward Premature Ejaculation in Mainland China: Infodemiology Study Using the Baidu Index

  https://www.jmir.org/2021/8/e30271/

  Premature ejaculation (PE) is one of the most described psychosocial stress and sexual complaints worldwide. The estimated PE prevalence rate is 16% and over 20% in an internet-based survey. The PE prevalence and its actual impact may hence remain unveiled and underestimated. The Baidu Index was queried using the PE-related terms for the period of January 2011 to December 2020. The annual percent change (APC) for the complaint topic was 48.80% (P<.001) for 2011 to 2014 and 16.82% (P<.001) for 2014 to 2020. The age distribution of those searching for topics related to PE showed that the population aged 20 to 40 years comprised nearly 70% of the total search inquiries. The fluctuating online popularity of PE searches reflects the real-time population demands. The PE BSI geographic distribution was calculated based on provincial data and sorted according to Chinese administrative divisions. The PE search popularity was dominated by searches from the East China, North China, and South China regions, where the top four Chinese megacities are located. PE was reported as the most common sexual complaint in males in all age groups in previous epidemiological studies. In our investigation, over 70% of PE online search queries came from males aged 20 to 39 years. The most popular term was "The fastest and easiest way to cure PE?" The relationship between PE and chronic prostatitis (CP) has been long observed. The most queried terms were related to selective serotonin reuptake inhibitors. The fluctuating online popularity of PE searches reflects the real-time population demands. [...] The internet search data could be more reliable when the insufficient and lagging registry data are completed.

• #62 Epidemiology of delayed ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5002002/

  The present review provides an overview of the current knowledge on the epidemiology of diminished ejaculatory disorders, with a focus on the acquired disease in specific populations at higher risk of developing DE and other forms of ejaculatory disorders. […] Ejaculatory dysfunctions in the aged male are most probably due to several comorbidities, including metabolic and cardiovascular disorders, increased prevalence of T deficiency, increased use of medications, and decreased exercise. […] These data highlight that during the entire lifespan, but in particular in old age, sexual issues should be adequately addressed by investigating illnesses that might contribute to sexual problems.

• #63 Why more sex may lower prostate cancer risk | Harvard T.H. Chan School of Public Health

  https://hsph.harvard.edu/news/why-more-sex-may-lower-prostate-cancer-risk/

  A number of studies have found that greater ejaculation frequency is associated with a reduced risk of prostate cancer. […] One such study was co-authored by Lorelei Mucci, professor of epidemiology at Harvard T.H. Chan School of Public Health. […] The 2016 study found that ejaculating more than 20 times per month reduced prostate cancer risk by about 20% compared to ejaculating only four to seven times per month, for both men in their 20s and 40s. […] One possible explanation for why frequent ejaculation might protect against prostate cancer is that it may help clear potentially cancer-causing substances from the prostate, Mucci said.

• #64 Epidemiology of delayed ejaculation

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5002002/

  The present review provides an overview of the current knowledge on the epidemiology of diminished ejaculatory disorders, with a focus on the acquired disease in specific populations at higher risk of developing DE and other forms of ejaculatory disorders. […] Ejaculatory dysfunctions in the aged male are most probably due to several comorbidities, including metabolic and cardiovascular disorders, increased prevalence of T deficiency, increased use of medications, and decreased exercise. […] These data highlight that during the entire lifespan, but in particular in old age, sexual issues should be adequately addressed by investigating illnesses that might contribute to sexual problems.

• #65 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/html

  These data highlight that during the entire lifespan, but in particular in old age, sexual issues should be adequately addressed by investigating illnesses that might contribute to sexual problems. […] After adjusting for age and common comorbidities, ejaculatory dysfunctions were significantly associated with LUTS and men with severe LUTS were 3.3 times more likely to report ejaculation disorders. […] This has a significant negative impact on quality of life, not only in regard to orgasmic function, but also for fertility, considering the relatively early onset of BPH.

• #66 Epidemiology of delayed ejaculation – Sante – Translational Andrology and Urology

  https://tau.amegroups.org/article/view/10793/11774

  After adjusting for age and common comorbidities, ejaculatory dysfunctions were significantly associated with LUTS and men with severe LUTS were 3.3 times more likely to report ejaculation disorders. […] These data highlight that during the entire lifespan, but in particular in old age, sexual issues should be adequately addressed by investigating illnesses that might contribute to sexual problems.

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