Problemy z ejakulacją
Leczenie
Zaburzenia ejakulacji, obejmujące przedwczesny wytrysk (PE), opóźniony wytrysk (DE), wytrysk wsteczny (RE) oraz anejakulację, wymagają kompleksowej diagnostyki obejmującej wywiad, badanie fizykalne oraz badania laboratoryjne (np. poziomy testosteronu, prolaktyny, TSH). PE, dotykający do 30% mężczyzn, leczony jest przede wszystkim farmakologicznie za pomocą selektywnych inhibitorów wychwytu zwrotnego serotoniny (SSRI) – dapoksetyna (stosowana doraźnie), sertralina, paroksetyna, fluoksetyna, citalopram, a także klomipramina. W terapii stosuje się także miejscowe anestetyki (np. lidokaina 150 mg/ml i prilokaina 50 mg/ml) oraz inhibitory PDE5 (sildenafil, tadalafil) w przypadku współistniejących zaburzeń erekcji. Interwencje behawioralne (techniki stop-start, ściskania, ćwiczenia Kegla) oraz terapia psychologiczna (terapia seksualna, CBT, terapia par) zwiększają skuteczność leczenia, szczególnie w podejściu multidyscyplinarnym, które łączy farmakoterapię z terapią behawioralną i psychologiczną.
- Leczenie problemów z ejakulacją
- Leczenie przedwczesnego wytrysku
- Farmakoterapia przedwczesnego wytrysku
- Techniki behawioralne w leczeniu przedwczesnego wytrysku
- Psychoterapia w leczeniu przedwczesnego wytrysku
- Podejście łączne do leczenia przedwczesnego wytrysku
- Leczenie opóźnionego wytrysku
- Leczenie przyczynowe opóźnionego wytrysku
- Farmakoterapia opóźnionego wytrysku
- Terapia psychoseksualna w leczeniu opóźnionego wytrysku
- Metody fizykalne w leczeniu opóźnionego wytrysku
- Leczenie wytrysku wstecznego
- Leczenie anejakulacji
- Podejście interdyscyplinarne do leczenia zaburzeń ejakulacji
- Skuteczność leczenia problemów z ejakulacją
Leczenie problemów z ejakulacją
Problemy z ejakulacją to powszechne zaburzenia seksualne u mężczyzn, które mogą istotnie wpływać na jakość życia seksualnego, relacje partnerskie oraz płodność. Leczenie tych zaburzeń zależy przede wszystkim od rodzaju problemu i jego przyczyny. W niniejszym artykule omówimy kompleksowe podejście do leczenia różnych rodzajów zaburzeń ejakulacji.123
Diagnostyka problemów z ejakulacją
Przed rozpoczęciem leczenia problemów z ejakulacją konieczne jest przeprowadzenie dokładnej diagnostyki. Badanie lekarskie i wywiad medyczny są często wystarczające do ustalenia przyczyny zaburzenia i zaproponowania odpowiedniego leczenia. W niektórych przypadkach mogą być jednak potrzebne dodatkowe badania lub konsultacja ze specjalistą.1
Diagnostyka powinna obejmować:
- Szczegółowy wywiad medyczny, uwzględniający aktualne i przebyte choroby
- Wywiad dotyczący przyjmowanych leków
- Badanie fizykalne
- W wybranych przypadkach badania laboratoryjne (np. poziom testosteronu, prolaktyny, TSH)
- Ocenę czynników psychologicznych i relacyjnych
Leczenie przedwczesnego wytrysku
Przedwczesny wytrysk (Premature Ejaculation, PE) jest najczęstszym zaburzeniem ejakulacji, dotykającym do 30% mężczyzn. Definiowany jest jako wytrysk, który następuje przed lub krótko po penetracji, bez możliwości kontroli i wywołujący dyskomfort psychiczny. Leczenie PE powinno uwzględniać zarówno czynniki biologiczne, jak i psychologiczne.678
Farmakoterapia przedwczesnego wytrysku
Choć żaden lek nie został oficjalnie zatwierdzony przez FDA do leczenia przedwczesnego wytrysku w USA, w Europie (w tym w Wielkiej Brytanii) dostępne są preparaty zarejestrowane w tym wskazaniu:893
- Selektywne inhibitory wychwytu zwrotnego serotoniny (SSRI) – stanowią podstawę farmakoterapii PE:
- Dapoksetyna (Priligy) – jedyny lek zarejestrowany w wielu krajach (w tym w UK) specjalnie do leczenia PE, szybko działający SSRI stosowany doraźnie
- Inne leki z grupy SSRI (stosowane off-label): sertralina, paroksetyna, fluoksetyna, citalopram
- Klomipramina (trójpierścieniowy lek przeciwdepresyjny)
- Środki miejscowo znieczulające:
- Aerozol zawierający lidokainę (150 mg/ml) i prilokainę (50 mg/ml) – pierwszy preparat miejscowy oficjalnie zatwierdzony przez EMA w Unii Europejskiej do leczenia PE
- Kremy, żele i spraye zawierające środki znieczulające (benzokaina, lidokaina, prilokaina) – aplikowane na penisa 10-15 minut przed stosunkiem
- Inhibitory fosfodiesterazy typu 5 (PDE5) – jak sildenafil (Viagra), tadalafil (Cialis) – szczególnie skuteczne, gdy PE współistnieje z zaburzeniami erekcji
- Inne leki:
- Tramadol – wykazuje korzyści w leczeniu PE
- Pindolol – może zwiększyć skuteczność leczenia SSRI u pacjentów, którzy nie reagują na monoterapię
Techniki behawioralne w leczeniu przedwczesnego wytrysku
Interwencje behawioralne mogą być stosowane jako samodzielne leczenie lub w połączeniu z farmakoterapią:141015
- Technika stop-start – polega na rozpoczęciu stymulacji seksualnej do momentu odczucia zbliżającego się wytrysku, a następnie przerwaniu stymulacji i wznowieniu jej po ustąpieniu uczucia
- Technika ściskania (squeeze) – partner ściska penis u podstawy żołędzi przez 10-20 sekund, gdy mężczyzna zbliża się do wytrysku, co zapobiega ejakulacji i zmniejsza siłę erekcji
- Ćwiczenia mięśni dna miednicy (ćwiczenia Kegla) – wzmacniają mięśnie dna miednicy, co może pomóc w kontroli wytrysku
- Masturbacja przed stosunkiem – może pomóc w opóźnieniu wytrysku podczas późniejszego stosunku
- Przedłużona gra wstępna
- Rozpraszanie uwagi – techniki poznawcze polegające na myśleniu o czymś innym w celu opóźnienia wytrysku
- Regularna aktywność seksualna
- Aktywność fizyczna – umiarkowana aktywność fizyczna trwająca dłużej niż 30 minut, co najmniej 5 razy w tygodniu, może opóźniać wytrysk
Psychoterapia w leczeniu przedwczesnego wytrysku
Leczenie psychologiczne jest szczególnie ważne w przypadkach, gdy przedwczesny wytrysk ma podłoże psychogenne:1816
- Terapia seksualna – łączy psychoterapię ze strukturalizowanymi zmianami w życiu seksualnym
- Terapia poznawczo-behawioralna (CBT) – pomaga zidentyfikować i zmienić negatywne wzorce myślenia i zachowania
- Terapia par – angażuje partnera/partnerkę w proces leczenia
- Techniki mindfulness – pomagają zmniejszyć lęk związany z wydajnością seksualną
- Terapia redukcji lęku
Podejście łączne do leczenia przedwczesnego wytrysku
Największą skuteczność w leczeniu przedwczesnego wytrysku wykazuje podejście multidyscyplinarne, łączące różne metody terapeutyczne:108
- Kombinacja farmakoterapii i terapii behawioralnej/psychologicznej daje lepsze wyniki niż każda z tych metod stosowana osobno
- Podejście multimodalne uwzględniające wszystkie czynniki psychologiczne, interpersonalne, poznawcze i relacyjne
- W przypadku pierwotnego PE (występującego od początku aktywności seksualnej) zaleca się połączenie farmakoterapii z terapią seksualną
- W przypadku wtórnego PE (nabytego) leczenie powinno być ukierunkowane na przyczynę, np. zaburzenia erekcji, problemy urologiczne, stres
Leczenie opóźnionego wytrysku
Opóźniony wytrysk (Delayed Ejaculation, DE) charakteryzuje się znacznym opóźnieniem lub niemożnością osiągnięcia wytrysku i orgazmu pomimo odpowiedniej stymulacji seksualnej. Jest to trudniejsze do leczenia zaburzenie niż przedwczesny wytrysk, dotykające około 3-4% mężczyzn.194
Leczenie przyczynowe opóźnionego wytrysku
Leczenie opóźnionego wytrysku powinno być ukierunkowane na przyczynę:2223
- Modyfikacja farmakoterapii – jeśli przyczyną jest przyjmowanie leków (np. SSRI, leki przeciwpsychotyczne, leki przeciwnadciśnieniowe, alfa-adrenolityki):
- Zmniejszenie dawki lub zmiana leku na alternatywny
- W przypadku antydepresantów rozważenie zmiany na bupropion, mirtazapinę, nefazodon lub wilazodon, które mają mniej działań niepożądanych w sferze seksualnej
- Leczenie chorób współistniejących – np. cukrzycy, chorób tarczycy, nadciśnienia
- Leczenie zaburzeń hormonalnych – np. suplementacja testosteronu w przypadku hipogonadyzmu
- Zmiana nawyków masturbacyjnych – szczególnie w przypadku idiosynkratycznych technik masturbacji
Farmakoterapia opóźnionego wytrysku
Obecnie nie ma leków zatwierdzonych przez FDA do leczenia opóźnionego wytrysku, jednak kilka preparatów jest stosowanych off-label:264
- Kabergolina – agonista receptorów dopaminowych, w badaniach wykazuje skrócenie czasu do ejakulacji
- Bupropion – atypowy antydepresant, który może poprawić funkcje seksualne
- Cyproheptadyna (Periactin) – lek przeciwalergiczny z działaniem przeciwserotoninowym
- Amantadyna (Symmetrel) – lek stosowany w chorobie Parkinsona
- Buspiron (Buspar) – lek przeciwlękowy
- Oksytocyna – może wspomagać ejakulację
- Leki sympatykomimetyczne:
- Midodryna
- Efedyna
- Pseudoefedryna
- Imipramina – trójpierścieniowy lek przeciwdepresyjny
- Johimbina – antagonista receptorów α2-adrenergicznych
- Betancholina – agonista receptorów cholinergicznych
- Inhibitory PDE5 (np. sildenafil, tadalafil) – w przypadku współistniejących zaburzeń erekcji
Terapia psychoseksualna w leczeniu opóźnionego wytrysku
Leczenie psychologiczne odgrywa kluczową rolę, szczególnie gdy opóźniony wytrysk ma podłoże psychogenne:2927
- Terapia seksualna – obejmuje edukację seksualną i psychoterapię ukierunkowaną na problemy seksualne
- Przetrening masturbacyjny – modyfikacja technik masturbacji, aby bardziej przypominały doznania podczas stosunku
- Terapia poznawczo-behawioralna – pomaga w identyfikacji i zmianie nieadaptacyjnych przekonań i zachowań związanych z seksualnością
- Mindfulness – techniki uważności, które pomagają skupić się na doznaniach seksualnych
- Terapia par – angażuje partnera/partnerkę w proces leczenia
- Terapia psychodynamiczna – eksploracja ukrytych konfliktów, które mogą wpływać na funkcje seksualne
Metody fizykalne w leczeniu opóźnionego wytrysku
Metody fizykalne mogą być pomocne w niektórych przypadkach opóźnionego wytrysku:245
- Stymulacja wibracyjna – aplikacja elektrowibratora na dolną powierzchnię żołędzi penisa może skutecznie wywołać ejakulację, szczególnie w przypadkach pierwotnego anorgazmu męskiego
- Terapia próżniowa (vacuum therapy) – może poprawić przepływ krwi i wrażliwość penisa
- Techniki trakcji penisa – mogą przynieść pewne korzyści w leczeniu
- Terapia falami uderzeniowymi (shockwave therapy) – nowatorska metoda mogąca poprawić funkcje seksualne
Leczenie wytrysku wstecznego
Wytrysk wsteczny (Retrograde Ejaculation, RE) występuje, gdy nasienie przepływa wstecznie przez szyję pęcherza do pęcherza moczowego zamiast być wyrzucane przez cewkę moczową. W większości przypadków nie wymaga leczenia, chyba że stanowi przyczynę niepłodności.332
Farmakoterapia wytrysku wstecznego
Leczenie farmakologiczne ma na celu poprawę zamykania szyi pęcherza podczas ejakulacji:33
- Leki sympatykomimetyczne:
- Pseudoefedryna
- Efedryna
- Fenylefryna
- Trójpierścieniowe leki przeciwdepresyjne:
- Imipramina
- Leki α-adrenergiczne:
- Midodryna
- Leki przeciwhistaminowe:
- Chlorfeniramina
- Difenhydramina
- Iniekcje kolagenu do szyi pęcherza – mogą poprawić jej zamykanie
Leczenie niepłodności przy wytrysku wstecznym
Gdy celem leczenia jest osiągnięcie ojcostwa, możliwe są następujące metody:35
- Pobieranie nasienia z moczu po ejakulacji i wykorzystanie go do zapłodnienia
- Techniki wspomaganego rozrodu:
- Inseminacja domaciczna (IUI)
- Zapłodnienie in vitro (IVF)
- Docytoplazmatyczna iniekcja plemnika (ICSI)
- Chirurgiczna rekonstrukcja mięśni zwieraczy pęcherza – rzadko stosowana
Leczenie anejakulacji
Anejakulacja to całkowity brak wytrysku pomimo osiągnięcia orgazmu (anejaculatio) lub brak zarówno wytrysku, jak i orgazmu (anorgazmia). Leczenie zależy od przyczyny i celu terapii (poprawa funkcji seksualnych lub leczenie niepłodności).3637
Leczenie psychogennej anejakulacji
Gdy anejakulacja ma podłoże psychologiczne:3238
- Psychoterapia – aby rozwiązać problemy z lękiem, stresem i pewności siebie
- Terapia seksualna – techniki ukierunkowane na poprawę funkcji seksualnych
- Leki przeciwlękowe – w przypadku znacznego lęku związanego z aktywnością seksualną
Metody pozyskiwania nasienia w anejakulacji
W przypadkach gdy celem jest leczenie niepłodności:3936
- Stymulacja wibracyjna penisa (PVS) – nieinwazyjna metoda pierwszego wyboru, skuteczna u około 75% pacjentów, szczególnie w przypadkach uszkodzenia rdzenia kręgowego
- Elektroejakulacja (EEJ) – bardziej inwazyjna metoda, polegająca na wprowadzeniu sondy do odbytnicy i stymulacji elektrycznej nerwów w okolicy prostaty; skuteczna w około 90% przypadków
- Pobieranie nocnych emisji nasienia – zbieranie nasienia w prezerwatywę podczas nocnych polucji
- Pobranie nasienia z cewki sterczowej – w przypadku dyssynergii ejakulacji
- Chirurgiczne pobranie plemników:
- Mikrochirurgiczna ekstrakcja plemników z jąder (microTESE)
- Aspiracja nasienia z najądrzy lub nasieniowodów
Podejście interdyscyplinarne do leczenia zaburzeń ejakulacji
Niezależnie od rodzaju zaburzenia ejakulacji, najbardziej skuteczne jest podejście interdyscyplinarne, uwzględniające zarówno aspekty biologiczne, jak i psychologiczne:189
- Podejmowanie wspólnych decyzji (shared decision-making) – pacjent powinien być aktywnie zaangażowany w wybór metody leczenia
- Zaangażowanie partnera/partnerki – gdy to możliwe, partner/partnerka powinien/powinna być włączony/a w proces terapeutyczny
- Leczenie chorób współistniejących – np. zaburzeń erekcji, zapalenia prostaty, cukrzycy
- Modyfikacja stylu życia – redukcja stresu, ograniczenie spożycia alkoholu i nikotyny, regularna aktywność fizyczna
- Edukacja seksualna – dostarczenie pacjentowi rzetelnej wiedzy na temat fizjologii seksualnej
Nowoczesne kierunki w leczeniu zaburzeń ejakulacji
Trwają badania nad nowymi metodami leczenia zaburzeń ejakulacji:4141
- Terapia falami uderzeniowymi (shockwave therapy) – nieinwazyjna metoda poprawiająca funkcje seksualne, pierwotnie stosowana w leczeniu zaburzeń erekcji, obecnie badana również w leczeniu przedwczesnego wytrysku
- Przezskórna stymulacja elektryczna nerwu piszczelowego (TPTNS) – nieinwazyjna metoda neuromodulacji
- Plazma bogatopłytkowa (PRP) – iniekcje autologicznej osocza bogatego w płytki krwi
- Urządzenia do wspomagania masturbacji w połączeniu z technikami behawioralnymi
- Patch In2 – urządzenie wykorzystujące stymulację elektryczną mięśni ejakulacyjnych w celu przedłużenia czasu trwania stosunku
- Neuromodulacja za pomocą fal radiowych – obiecujące wyniki w leczeniu przedwczesnego wytrysku
Skuteczność leczenia problemów z ejakulacją
Skuteczność leczenia zaburzeń ejakulacji zależy od wielu czynników, w tym od rodzaju zaburzenia, jego przyczyny, wybranej metody leczenia oraz zaangażowania pacjenta i jego partnera/partnerki.4322
- W przypadku przedwczesnego wytrysku skuteczność leczenia wynosi około 60-80%, przy czym najlepsze wyniki osiąga się przy zastosowaniu podejścia łączącego farmakoterapię i techniki behawioralne
- Leczenie opóźnionego wytrysku jest bardziej wymagające, a jego skuteczność zależy głównie od przyczyny – w przypadku zaburzeń związanych z lekami prognoza jest lepsza niż w przypadku zaburzeń pierwotnych
- Wytrysk wsteczny rzadko wymaga leczenia, chyba że stanowi przyczynę niepłodności; proste terapie farmakologiczne mają dobrą szansę na zmniejszenie nasilenia objawów na tyle, by umożliwić poczęcie
- W przypadku anejakulacji skuteczność leczenia zależy od przyczyny – gdy przyczyną jest uszkodzenie nerwów, techniki wspomaganej ejakulacji (PVS, EEJ) pozwalają na pozyskanie nasienia u większości pacjentów
Warto podkreślić, że leczenie zaburzeń ejakulacji wymaga indywidualnego podejścia, a wybór metody terapeutycznej powinien uwzględniać preferencje pacjenta, jego sytuację osobistą, a także dostępność danej metody i doświadczenie lekarza prowadzącego.91
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Materiały źródłowe
- #1 Delayed ejaculation – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/delayed-ejaculation/diagnosis-treatment/drc-20371363
A physical exam and medical history might be all that are needed to suggest treatment for delayed ejaculation. But there might be a problem causing delayed ejaculation that needs treatment. Then you might need more tests, or you might need to see a specialist. […] Delayed ejaculation treatment depends on the cause. Treatment might include taking medicine or making changes to medicines you take. It might involve psychological counseling or addressing alcohol or illicit drug use. […] Counseling can help by dealing with mental health problems linked to delayed ejaculation, such as depression or anxiety. […] Treatment often is more successful if couples work together as a team. You might want to see a counselor with your partner. This can help you address concerns you both might have about delayed ejaculation. […] For delayed ejaculation, some basic questions to ask include: What treatments are there? Which one do you suggest for me?
- #2 Delayed Ejaculation: Causes, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/22125-delayed-ejaculation
If you have delayed ejaculation, you or your partner may find sexual intercourse frustrating instead of pleasurable because of the time it takes you to ejaculate. Treatment may include therapy or changes to your medications. […] A healthcare provider may offer several different delayed ejaculation treatments. A provider may also recommend that you speak with a therapist (psychotherapy) or sex therapist. If delayed ejaculation happens primarily with your partner, they may suggest counseling for both of you. […] The U.S. Food and Drug Administration (FDA) hasn’t approved a drug treatment for delayed ejaculation. […] Kegel exercises help strengthen the muscles in your pelvic floor. Strengthening your pelvic floor may give you greater control over when you ejaculate. […] Talk to a healthcare provider as soon as you have problems ejaculating. If you have difficulty ejaculating with a partner, talking to a therapist can help.
- #3 Ejaculation problemshttps://www.nhs.uk/conditions/ejaculation-problems/
Ejaculation problems are common sexual problems in men. […] If you have a persistent problem with ejaculation, visit your GP, who will discuss the problem with you and may examine you or refer you to a specialist. […] Occasional episodes of premature ejaculation are common and are not a cause for concern. However, if you’re finding that it happens more than you’d like, and it’s a problem for you, it might help to get treatment. […] Selective serotonin reuptake inhibitors (SSRIs) are a type of antidepressant, but they also delay ejaculation. […] An SSRI specifically designed to treat premature ejaculation, known as dapoxetine (Priligy), has been licensed in the UK. […] Phosphodiesterase-5 inhibitors, such as sildenafil (sold as Viagra), are a class of medicine used to treat erectile dysfunction. Research has found that they may also help with premature ejaculation.
- #3 Ejaculation problemshttps://www.nhs.uk/conditions/ejaculation-problems/
The use of topical anaesthetics such as lidocaine or prilocaine can help but may be transferred and absorbed to the vagina, causing decreased sensation. […] You may benefit from having psychosexual counselling, where a therapist can help you, and a partner if you have one, with sex related problems. […] Sex therapy is a form of counselling that uses a combination of psychotherapy and structured changes in your sex life. This can help to increase your feeling of enjoyment during sex and help make ejaculation easier. […] There are a number of medicines that can be used if it’s thought SSRIs are responsible for causing delayed ejaculation. […] Pseudoephedrine tablets may be tried, but these will need to be prescribed „off-label”. […] Most men do not need treatment for retrograde ejaculation because they are still able to enjoy a healthy sex life and the condition does not have adverse effects on their health. […] But if treatment is required (usually because of wanting to father a child), there are options to try. […] If you’re having problems with your sex life and are seeking treatment, it is usually recommended you involve your partner as much as possible.
- #4 Male delayed orgasm and anorgasmia: a practical guide for sexual medicine providers | International Journal of Impotence Researchhttps://www.nature.com/articles/s41443-023-00692-7
Delayed orgasm (DO) is defined as increased latency of orgasm despite adequate sexual stimulation and desire. Anorgasmia (AO) is characterized as the absence of orgasm. […] Treating DO/AO can be challenging due to the lack of standardized FDA-approved pharmacotherapies. There is no standardized treatment plan for DO/AO, though common treatments plans are often multidisciplinary and may include adjustment of offending medications and sex therapy. […] Compared to ED where reliable and well-studied treatments are available, there remains a paucity of standardized treatments for men with ejaculatory and/or orgasmic dysfunction. […] In this review, we specifically focus on summarizing the current knowledge regarding the epidemiology, pathophysiology, diagnosis, and treatment of DO/AO. […] There is no standardized treatment plan for DO. Treatment plans are often multidisciplinary, involving urologists, primary care providers and mental health professionals to adequately address biopsychosocial factors.
- #4 Male delayed orgasm and anorgasmia: a practical guide for sexual medicine providers | International Journal of Impotence Researchhttps://www.nature.com/articles/s41443-023-00692-7
Testosterone replacement is indicated for men with testosterone deficiency in accordance with available guidelines. […] Psychosocial evaluation with a sex therapist is recommended for all patients. […] Exact rates of success are difficult to determine based on existing literature due to variability of therapy methods and lack of large-scale studies. […] Though there are no drugs approved by the U.S. Food and Drug Administration (FDA) at this time due to the absence of conclusive data, several pharmacological therapies show promise in treatment of DO including cabergoline, bupropion, oxytocin, and recently amphetamine/dextroamphetamine (AdderallTM). […] Choosing the right oral pharmacotherapy for a patient after addressing organic causes and considering sex therapy can be challenging. […] Some more invasive non-pharmacological therapies have been explored including intracavernosal injections of platelet rich plasma, pudendal nerves release, and surgical procedures.
- #5 Delayed Ejaculation Treatment & Management: Pharmacotherapy, Psychological Interventionshttps://emedicine.medscape.com/article/2184956-treatment
When pharmacotherapy for delayed ejaculation (DE) is under consideration, it is important to eliminate iatrogenic causes, including medications (eg, alpha-adrenergic blockers, other antihypertensives, antidepressants, and antipsychotics). […] In the case of antidepressant-induced inhibited male orgasm, consideration may be given to switching to bupropion (also used as adjunctive therapy), mirtazapine, nefazodone, or vilazodone, which have fewer sexual side effects than selective serotonin reuptake inhibitors (SSRIs) do. […] Adjunctive therapies should be considered. Alpha sympathomimetics (eg, ephedrine or a combination of chlorpheniramine maleate and phenylpropanolamine hydrochloride [withdrawn from the US market]) have been used successfully in patients with retrograde ejaculation. […] Sildenafil and imipramine appear to be effective in psychotropic-induced male orgasmic disorder (MOD).
- #5 Delayed Ejaculation Treatment & Management: Pharmacotherapy, Psychological Interventionshttps://emedicine.medscape.com/article/2184956-treatment
Any psychological intervention must address both historical factors and current factors that might contribute to the present dysfunction. […] A psychodynamic-oriented treatment aims to explore and understand such factors, decrease secondary feelings such as anxiety and guilt, and correct negative cognitions that can result in psychological inhibition and orgasmic dysfunction. […] Counseling should be provided for patients who have normal wet dreams but cannot achieve orgasm and ejaculation during sexual activity. […] In addition to psychotherapy, anecdotal reports suggest that an electrovibrator applied at the lower surface of the glans penis can be an effective intervention in cases of primary male anorgasmia.
- #6 Premature Ejaculation – Men’s Health Issues – Merck Manual Consumer Versionhttps://www.merckmanuals.com/home/men-s-health-issues/sexual-function-and-dysfunction-in-men/premature-ejaculation
Premature ejaculation is ejaculation that occurs too early, usually before, upon, or shortly after penetration. […] Behavior modification therapy, including strategies to delay ejaculation, helps most men. […] Behavior modification therapy can help most men overcome premature ejaculation. A therapist provides reassurance, explains why premature ejaculation occurs, and teaches the man strategies for delaying ejaculation. […] Other methods that can help a man delay ejaculation include medications (with a selective serotonin reuptake inhibitor such as fluoxetine, paroxetine, or sertraline or with a tricyclic antidepressant such as clomipramine). Local treatments, which tend to decrease sensation, such as application of an anesthetic (lidocaine cream) to the penis and use of condoms, may help men delay ejaculation. Sometimes a combination of medication and behavior modification therapy may be needed. When premature ejaculation is caused by more serious psychological problems, psychotherapy may help.
- #7 Premature ejaculation | Better Health Channelhttps://www.betterhealth.vic.gov.au/health/healthyliving/premature-ejaculation
Premature ejaculation is the most common sexual problem in the world. […] There is a variety of treatments to choose from, including exercises, therapy and medications. […] You should be reassured that premature ejaculation is very common and there are effective treatments that can help. […] Your doctor can help you identify the reason for your premature ejaculation and find a suitable treatment, so you should see them if your sexual function is a cause of concern for you. […] Treatment of premature ejaculation is successful in 30-70% of cases. […] Lifelong premature ejaculation cannot be cured but it can be managed with ongoing treatment. […] Acquired premature ejaculation may be cured by successfully treating the underlying issue. […] Talking with a GP (doctor), psychologist, sex therapist or other mental health professional may help.
- #8 Premature Ejaculation Treatment & Management: Approach Considerations, Pharmacologic Therapy, Counseling and Sex Therapyhttps://emedicine.medscape.com/article/435884-treatment
Medical treatment for premature (early) ejaculation includes several options. Any serious primary medical condition (eg, angina) should be treated; for the purposes of the following discussion, the patient is assumed to be healthy, and premature ejaculation is assumed to be his only problem. In addition, any accompanying erection problem (eg, erectile dysfunction [ED]) should be treated; various methods are available, and excellent success can be expected. Accordingly, treatment of concomitant ED is mentioned only in passing. […] To achieve the best outcome, the female partner should be included as fully as possible in the treatment and counseling sessions. Pharmacologic therapy may include selective serotonin reuptake inhibitors (SSRIs) or topical desensitizing agents. […] To date, no drug has been specifically approved by the US Food and Drug Administration (FDA) for the treatment of premature ejaculation. However, numerous studies have shown that selective serotonin reuptake inhibitors (SSRIs) and drugs with SSRI-like side effects are safe and effective to treat this condition, and many physicians use these agents for this purpose. Topical desensitizing therapy with local anesthetic agents can also be useful in some men with premature ejaculation.
- #9 Disorders of Ejaculation: An AUA/SMSNA Guideline (2020) – American Urological Associationhttps://www.auanet.org/guidelines-and-quality/guidelines/disorders-of-ejaculation
The role of the clinician in managing PE and DE is to conduct appropriate investigation, to provide education, and to offer available treatments that are rational and based on sound scientific data. […] The Panel recommends shared decision-making as fundamental in the management of disorders of ejaculation; involvement of sexual partner(s) in decision making, when possible, may allow for optimization of outcomes. […] Clinicians should recommend daily SSRIs; on demand clomipramine or dapoxetine (where available); and topical penile anaesthetics as first-line pharmacotherapies in the treatment of premature ejaculation. […] Clinicians should advise men with premature ejaculation that combining behavioral and pharmacological approaches may be more effective than either modality alone. […] Clinicians should inform patients that there is insufficient evidence to support the use of alternative therapies in the treatment of premature ejaculation.
- #10 Premature ejaculation – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/premature-ejaculation/diagnosis-treatment/drc-20354905
Condoms might make the penis less sensitive, which can help delay ejaculation. Specially designed „climax control” condoms are available without a prescription. […] Creams, gels and sprays that contain a numbing agent such as benzocaine, lidocaine or prilocaine are sometimes used to treat premature ejaculation. They’re applied to the penis 10 to 15 minutes before sex to reduce sensation and help delay ejaculation. […] Many medications might delay orgasm. These drugs aren’t approved by the Food and Drug Administration to treat premature ejaculation, but some are used for this purpose. […] Counseling is most likely to help when it’s used in combination with drug therapy. […] Premature ejaculation can cause partners to feel less connected or hurt. Talking about the problem is an important step. Relationship counseling or sex therapy also might be helpful. […] Deciding to talk with your health care provider is an important step. In the meantime, consider exploring other ways in which you and your partner can connect. Although premature ejaculation can cause strain and anxiety in a relationship, it is a treatable condition.
- #10 Premature ejaculation – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/premature-ejaculation/diagnosis-treatment/drc-20354905
Common treatment options for premature ejaculation include behavioral techniques, medications and counseling. It might take time to find the treatment or combination of treatments that work for you. Behavioral treatment plus drug therapy might be the most effective. […] In some cases, therapy for premature ejaculation involves simple steps. They may include masturbating an hour or two before intercourse. This may allow you to delay ejaculation when you have sex with your partner. […] Weak pelvic floor muscles might make it harder to delay ejaculation. Pelvic floor exercises (Kegel exercises) can help strengthen these muscles. […] Your health care provider might instruct you and your partner to use the pause-squeeze technique. This method works as follows: Begin sexual activity, including stimulating the penis, until you feel almost ready to ejaculate.
- #11 Premature Ejaculation Treatment & Management: Approach Considerations, Pharmacologic Therapy, Counseling and Sex Therapyhttps://emedicine.medscape.com/article/435884-treatment
Premature ejaculation that relates to erectile dysfunction may resolve if the erectile dysfunction is treated successfully. […] The most effective pharmacologic therapy for premature ejaculation is to administer a drug from the SSRI class. […] SSRIs useful for treating premature ejaculation include the following: Sertraline, Paroxetine, Fluoxetine, Citalopram, Dapoxetine. […] A systematic review and meta-analysis reported that although fluoxetine was more effective than placebo in treating PE, sertraline and paroxetine were more effective than fluoxetine. […] Dapoxetine, which is generally categorized as a fast-acting SSRI, was developed specifically to treat this condition. […] The optimal medical treatment regimen for premature ejaculation has not been established. […] There is no reason why pharmacotherapy cannot be combined with behavioral modification therapy, desensitizing creams, or both; the use of several simultaneous treatments can result in additive effects or even synergy.
- #12 Premature Ejaculation Treatment & Management: Approach Considerations, Pharmacologic Therapy, Counseling and Sex Therapyhttps://emedicine.medscape.com/article/435884-treatment
If all treatment fails, then the patients only options are as follows: To see a different health care professional, if he wishes; To accept his condition as being untreatable with currently available therapeutic options. […] Adverse effects of long-term SSRI use are a significant concern and should be considered by both the physician and the patient. […] Some studies have demonstrated that combining phosphodiesterase type 5 (PDE5) inhibitors with SSRIs provides better results in the treatment of premature ejaculation than using SSRIs alone. […] A single-blind randomized placebo-controlled clinical study in 100 patients concluded that tadalafil, 5 mg once daily for 6 weeks, was significantly more effective than placebo and was well tolerated in the treatment of premature ejaculation. […] A study by Safarinejad demonstrated that a single daily high dose of pindolol in combination with paroxetine delayed ejaculation in patients in whom paroxetine therapy alone failed to provide benefit.
- #12 Premature Ejaculation Treatment & Management: Approach Considerations, Pharmacologic Therapy, Counseling and Sex Therapyhttps://emedicine.medscape.com/article/435884-treatment
In a randomized double-blind, placebo-controlled clinical trial by Hamidi-Madani et al in 150 patients, 12 weeks of tramadol 50 mg on demand, paroxetine 20 mg on demand, and placebo all resulted in improvement, but the tramadol group experienced significantly greater benefit than the paroxetine and placebo groups. […] The first step is to attempt to relieve any underlying performance pressure on the male. […] Most couples find this technique to be highly successful. […] Kilinc et al reported that moderate physical activity longer than 30 min at least 5 times a week leads to ejaculation delay in patients with premature ejaculation. […] Surgical procedures that reduce penile sensation have been proposed as treatments for premature ejaculation. […] Consultation with a sex therapist, psychologist, or psychiatrist may prove helpful if the primary care physician or urologist cannot provide successful treatment or does not have the time to explore psychological issues and implement behavioral techniques.
- #13 Delayed or Absent Ejaculation | Department of Urology | UPMChttps://www.upmc.com/services/urology/conditions/delayed-or-absent-ejaculation
- #14 Ejaculatory Disorder Treatments | University of Utah Healthhttps://healthcare.utah.edu/fertility/conditions/ejaculatory-disorders/treatment
Our urologists have the expertise to diagnose and treat the root cause of your ejaculation disorder. Anything from psychological barriers to nerve damage may lead to ejaculation issues. We offer treatments for a range of causes, including the following: […] Several psychological, behavioral, and physical therapies can treat premature ejaculation. We recommend a few treatments: […] This treatment helps you learn to identify or regain control over your point of climax. […] This is a variation of the Masters and Johnson method. […] Over-the-counter gels, creams, and sprays may help decrease sensation so you can last longer. […] Some medications can delay or slow down orgasms: […] You might research other ways to treat premature ejaculation that dont work. […] The way we treat delayed ejaculation can vary widely based on the underlying cause.
- #15 The GP Guide: How to diagnose and treat ejaculatory disorders | Healthy Malehttps://healthymale.org.au/health-article/gp-guide-how-diagnose-and-treat-ejaculatory-disorders
If PE is associated with ED, treat the primary cause. For example, prescribe PDE5 inhibitors. […] Behavioural techniques include: Stop-start and squeeze techniques, Extended foreplay, Pre-intercourse masturbation, Cognitive distractions, Alternate sexual positions, Interval sex, Increased frequency of sex. […] Psychosexual counselling addresses the issue that has created the anxiety or psychogenic cause. It can also introduce methods to improve ejaculatory control, for example, meditation, relaxation, hypnotherapy and neuro-biofeedback. […] For common SSRI dosing regimes, see our clinical summary guide. A side-effect of some selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants is delayed ejaculation, so they are commonly prescribed for PE. […] For primary PE, most men require ongoing treatment to maintain normal function. First-line treatments are SSRIs and reducing penile sensation. Behavioural techniques and/or psychosexual counselling can be used as second-line treatments.
- #16https://www.laparoscopyhospital.com/forum/forum.php?p=&cat_id=&tid=3540
If you’re experiencing difficulties with ejaculation, it could be related to various factors, including physical or psychological issues. Here are some lifestyle changes that might be beneficial: Maintain a Healthy Diet: Eat a balanced diet rich in fruits, vegetables, lean proteins, and whole grains. Consider foods that support cardiovascular health, as good blood flow is crucial for sexual function. […] Yes, psychological factors such as stress, anxiety, and depression can indeed contribute to ejaculation problems. Conditions like premature ejaculation or delayed ejaculation can be influenced by various psychological factors. […] Premature ejaculation (PE) can be distressing, but there are several approaches that can help improve the condition. Here are some lifestyle changes and treatments you might consider: Behavioral Techniques: The start-stop technique: This involves stopping sexual stimulation before you reach the point of ejaculation and restarting once the urge to climax has passed. The squeeze technique: Your partner squeezes the base of your penis for about 30 seconds when you’re close to ejaculating, which helps reduce your erection. Pelvic floor exercises (Kegel exercises): These can help improve your control over ejaculation.
- #16https://www.laparoscopyhospital.com/forum/forum.php?p=&cat_id=&tid=3540
Medications: Topical anesthetics: These creams or sprays can numb the penis, reducing sensitivity and delaying ejaculation. Antidepressants: Some antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), can delay ejaculation. However, they are not specifically approved for this use, so it’s important to discuss the risks and benefits with your doctor. […] Counseling or Therapy: Sex therapy: A therapist can help you address psychological factors contributing to premature ejaculation and teach techniques to improve control. Couples therapy: Involving your partner in therapy can improve communication and intimacy, which may help with PE.
- #17 Premature ejaculation: Causes, Symptoms, Treatment & Cure PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact Numberhttps://www.pacehospital.com/premature-ejaculation-causes-symptoms-treatment-cure
This is because every aspect of the problem are addressed, including the underlying psychological, interpersonal, cognitive, and relationship issues that caused and supported the condition. […] Non-pharmacological treatment of premature ejaculation (treatment without medications): […] – Meditation/relaxation, hypnotherapy: These methods can help improve ejaculatory control. […] – Precoital masturbation: This is another non-pharmacological treatment. […] – Extended foreplay: This can be a helpful strategy. […] – Cognitive distraction: Cognitive distraction might be useful. […] – Alternate sex positions: Trying different positions may offer some benefit. […] – Interval sex: This involves taking breaks during sexual activity. […] – Increasing frequency of sex: More frequent sexual activity may help.
- #17 Premature ejaculation: Causes, Symptoms, Treatment & Cure PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact Numberhttps://www.pacehospital.com/premature-ejaculation-causes-symptoms-treatment-cure
The common drug classes that are used to manage premature ejaculation include: […] – Topical anaesthetics […] – Selective serotonin reuptake inhibitors (SSRIS) […] – Non-selective beta-adrenergic blockers […] – Alpha-adrenergic blockers […] – Opioid analgesics […] – Phosphodiesterase 5 inhibitors (PDE5 inhibitors) […] – Tricyclic antidepressants […] The negative feelings and ideas that might cause issues in sexual relationships can be addressed through psychotherapy. It can boost the patient’s sexual confidence and help them feel less nervous about having an intercourse. In individuals with perceived premature ejaculation or underlying psychological issues (when the intravaginal latency time is actually normal), it is the recommended first-line treatment. […] Combination therapy with SSRI drugs, ejaculatory delay techniques, local desensitisation procedures, psychological support, and behavioural (sex) therapy has proven to be the most effective treatment for premature ejaculation.
- #18 Ejaculation Problems: Too Fast, Too Slow or Not at All? » Sexual Medicine » BUMChttps://www.bumc.bu.edu/sexualmedicine/informationsessions/ejaculation-problems-too-fast-too-slow-or-not-at-all/
Ejaculatory problems can have a devastating affect on self-esteem. […] Ejaculation problems may also contribute to a low libido and lack of interest in sexual activity. […] Traditional behavioral sex therapy for delayed ejaculation is as follows: the man begins by masturbating, then starts intercourse when he is almost ready to ejaculate. […] In July 2003, the World Health Organization recommended that the term pre-mature ejaculation be replaced by the more neutral phrase early ejaculation. […] By definition, early ejaculation is an ejaculation that occurs before it is desired. […] As mentioned, the most effective approach is a combination of psychological assistance and medical intervention. […] Urologists and other medical doctors typically treat early ejaculation with a combination of medications and creams.
- #18 Ejaculation Problems: Too Fast, Too Slow or Not at All? » Sexual Medicine » BUMChttps://www.bumc.bu.edu/sexualmedicine/informationsessions/ejaculation-problems-too-fast-too-slow-or-not-at-all/
Ejaculation Problems: Too Fast, Too Slow or Not at All? […] For men, erectile dysfunction and ejaculatory problems are the most common sexual difficulties. […] In the vast majority of cases, the most effective therapeutic approach for ejaculatory dysfunction is a combination of biologic and psychologic therapy. […] Regardless of the psychological issues, a good medical or urologic work-up is always encouraged before embarking on a behavioral treatment program. […] The psychological definition of delayed ejaculation refers to the inability to have an ejaculation during sexual intercourse. […] In many cases, the man himself may tend to delay treatment or to minimize the distress of the situation. […] In spite of the lack of information regarding delayed ejaculation, the most successful approach, for sex therapists, is to engage both members of the couple into addressing the problem.
- #19 Overcoming Ejaculation Problems: Delayed, Premature, and Retrograde Ejaculationhttps://www.webmd.com/men/features/overcoming-ejaculation-problems
Too fast? Too slow? Treating Ejaculation Problems […] Premature ejaculation is by far the biggest complaint that men have about their sexual performance. […] Delayed ejaculation affects a much smaller number of men — as few as 3%, according to some estimates. […] Retrograde ejaculation is the least common of the ejaculation problems. […] There are lots of different reasons for delayed ejaculation. […] Masturbation may also help men learn to control their level of arousal, which is essential for delaying orgasm. […] One time-honored technique for premature ejaculation is to distract yourself — to think about something boring or even disgusting to delay your orgasm. […] For men who aren’t helped by any of these techniques, there’s a pharmaceutical option. […] Instead of drugs, some men use a desensitizing cream to delay orgasm. […] Whatever your ejaculation problem, there are solutions. […] With some openness, some discussion, and maybe a few fun new techniques in the bedroom, you can overcome your ejaculation problem.
- #20 Premature Ejaculation Disorder Treatments: Psychotherapy and Morehttps://psychcentral.com/disorders/premature-ejaculation-treatment
There have been mixed professional opinions over the last few decades as to what is the ideal treatment for male sexual disorders. The best treatment for DSM-5 premature (early) ejaculation disorder ultimately depends on the etiology, or root cause, of the problem. […] If it is caused by another medication the male is being prescribed, it is suggested that they contact the prescribing physician and discuss medication solutions to the problem; these are easily obtained in most instances. […] Otherwise, if the patient or their doctor suspects a psychological issue as the source for their early ejaculation tendencies, a clinical psychologist who specializes in sexual disorders will be the optimal provider of treatment. […] Cognitive behavioral therapy (CBT) is the best evidence-based therapy for many psychological problems.
- #21 Premature ejaculation treatment – ROC Clinichttps://rocclinic.com/en/premature-ejaculation/treatment/
In the case of secondary premature ejaculation, the more treatable the cause is, the better the treatment will work. Treating urinary problems, erectile dysfunction or accompaniment during a stressful life phase are often sufficient to improve mild cases. In more advanced cases, multimodal treatment will be necessary, combining sex therapy, pelvic floor rehabilitation, anxiety-excitation control, occasionally supported by drugs. […] Regarding the different treatments, it is necessary to emphasize that multimodal treatment will achieve better results when compared to simpler strategies. […] Pelvic floor rehabilitation. The relationship between pelvic floor problems and problems in the sexual sphere has been demonstrated. Pelvic floor toning and rehabilitation will give a man greater sexual control and more ability to inhibit sexual response.
- #21 Premature ejaculation treatment – ROC Clinichttps://rocclinic.com/en/premature-ejaculation/treatment/
Medication. There are two main medications that can help us in the treatment of premature ejaculation. The first of these is Fortacin. Fortacin is a spray applied on the penis, which is a eutectic mixture of prilocaine and xylocaine, which decreases the sensitivity of the penis, and therefore delays the moment of orgasm. […] The second drug is dapoxetine. Dapoxetine is a short-acting selective serotonin reuptake inhibitor, which inhibits and delays the onset of orgasm. […] Anxiety and arousal control. Aimed at reducing the adrenergic tone and negative thoughts, as well as to „accustom” the man to increasingly higher levels of eroticism. […] Start and stop. It is surely the basis of the treatment, and consists of understanding and controlling the sexual response. […] In our experience the best treatment is multimodal, associating different strategies in a unified treatment.
- #21 Premature ejaculation treatment – ROC Clinichttps://rocclinic.com/en/premature-ejaculation/treatment/
Finally, a brief mention should be made of surgical treatments. There is much debate about their usefulness. […] Other treatments, such as dorsal penile nerve neurotomy, are considered experimental. Recently, radiofrequency neuromodulation has achieved promising results. […] Yes, pelvic floor rehabilitation can help you gain more sexual control.
- #22 Delayed ejaculation Information | Mount Sinai – New Yorkhttps://www.mountsinai.org/health-library/diseases-conditions/delayed-ejaculation
Delayed ejaculation is a medical condition in which a male cannot ejaculate easily or at all. […] If you have never ejaculated through any form of stimulation, see your health care provider to determine if the problem has a physical cause. […] See a therapist who specializes in ejaculation problems if you are unable to ejaculate in an acceptable amount of time. […] Therapy often involves a series of „homework” assignments. […] In cases where there is a problem with the relationship or a lack of sexual desire, you may need therapy to improve your relationship and emotional intimacy. […] Sometimes, hypnosis may be a helpful addition to therapy. […] If a medicine may be the cause of the problem, discuss other medicine options with your care provider. […] Treatment commonly requires about 12 to 18 sessions. The average success rate is 70% to 80%. […] If medicines are causing the problem, your provider may recommend switching or stopping the medicine, if possible. A full recovery is possible if this can be done.
- #23 Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatmenthttps://pmc.ncbi.nlm.nih.gov/articles/PMC5756804/
Defining firm recommendations to approach the treatment of DE/AE is difficult for a condition that is less common and heterogeneous, for which the literature is confined to case reports, case series, and small studies. […] A rigid treatment plan is not suitable for all patients. […] Factors that affect the choice of treatment strategies may include: Clinical judgment regarding the etiology of DE/AE and making sound decisions. […] Psychological interventions may additionally reinforce the therapeutic success of some patients. […] Many psychotherapeutic treatments have been described for the management of DE/AE, addressing known or suspected psychogenic causes. […] Attempts have been made to treat DE/AE using off-label medications based on pharmacological and physiologic considerations.
- #23 Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatmenthttps://pmc.ncbi.nlm.nih.gov/articles/PMC5756804/
However, an approved drug does not exist. […] Here again, a number of approaches can be employed. […] The simplest approach is to collect nocturnal emissions in a spermicide-free condom for assisted reproduction. […] The presence of spermatozoa in the prostatic urethra may be due to ejaculation dyssynergia. […] Assisted ejaculation in the form of PVS is the next choice for sperm retrieval in idiopathic AE and is the first choice in neurogenic AE because it is noninvasive and inexpensive. […] In the vast majority of these men, motile spermatozoa can be obtained through assisted ejaculation. […] Approaches for sperm recovery should be considered and employed in a step-wise fashion, starting with the most cost-effective and least invasive options.
- #24 Delayed Ejaculation â Menâs Clinic – The Men’s Clinic at UCLA | UCLA Healthhttps://www.uclahealth.org/medical-services/urology/mens-clinic-ucla/sexual-health/delayed-ejaculation
With our board-certified urologists at The Mens Clinic at UCLA, you can be assured you are getting an experienced physician performing your delayed ejaculation evaluation and treatment. […] The opposite of premature or rapid ejaculation is delayed ejaculation. This can be as, if not more, frustrating than its opposite. Delayed ejaculation is the inability of a man to achieve climax within a reasonable amount of time. […] Treatment for delayed ejaculation depends on its cause. For men with nerve injuries, sometimes they respond to medical vibrators placed at the tip of the penis to retrain the nerves to fire more rapidly. […] For men with hormone imbalances, the doctor needs to run some laboratory tests, specifically testosterone and prolactin levels to see if there’s an imbalance. Testosterone therapy can elevate blood flow to the penis, engorging it more and making the nerves more sensitive.
- #25 Delayed Ejaculation Causes, Diagnosis, Treatment, and Copinghttps://www.verywellhealth.com/delayed-ejaculation-3300047
Medical interventions may be explored if chronic conditions are not being managed, including high blood pressure, diabetes, and thyroid disease. […] Additionally, a psychologist or psychiatrist may help you overcome any emotional barriers that are standing in the way of an orgasm. […] If the cause is functional (meaning caused by sexual practices or habits), a sex therapist may use talk therapy or suggest toys, devices, or sexual and mental exercises to alter the way you approach sex and orgasm. […] Delayed ejaculation treatment depends on the underlying cause. Certain medications can help, and therapy may also be useful.
- #26 The drug treatment of delayed ejaculationhttps://pmc.ncbi.nlm.nih.gov/articles/PMC5001980/
Delayed ejaculation (DE) is an uncommon and a challenging disorder to treat. […] Here we reviewed how DE is treated pharmacologically. […] There are a number of drugs to treat patients with DE including: testosterone, cabergoline, bupropion, amantadine, cyproheptadine, midodrine, imipramine, ephedrine, pseudoephedrine, yohimbine, buspirone, oxytocin, and bethanechol. […] Although there are many pharmacological treatment options, the evidence is still limited to small trials, case series or case reports. […] It is concluded that successful drug treatment of DE is still in its infancy. […] Various drugs are available to address such problem, however their evidence of efficacy is still limited and their choice needs to be individualized to each specific case. […] Treatment should be etiology specific, and may include patient and their partner psychosexual therapy, drug therapy or integrated treatment.
- #26 The drug treatment of delayed ejaculationhttps://pmc.ncbi.nlm.nih.gov/articles/PMC5001980/
Currently, no drug has been approved by FDA for DE. […] In a recent survey to evaluate the current opinion and clinical management of DE by members of the Sexual Medicine Society of North America (SMSNA), cabergoline and bupropion were the most commonly selected first line treatments for DE. […] The choice of management option should be guided by the etiologic factor, illness characteristics (DE or anejaculation), patient preferences, and physicians comfort with different. […] To conclude, successful drug treatment of DE is still in its infancy. The clinicians need to be aware of the pathogenesis of DE and the pharmacological basis underlying the use of different drugs to extend better care to the patients.
- #27 Delayed Ejaculation: Informed Diagnosis and Treatment | Psychology Todayhttps://www.psychologytoday.com/us/blog/sexual-tipping-point/201812/delayed-ejaculation-informed-diagnosis-and-treatment
Men with DE find it difficult or impossible to ejaculate and/or experience orgasm. […] Diagnosis of DE requires distress about the symptom(s), adequate sexual stimulation, and a conscious desire to achieve orgasm. […] Many physicians, for better and sometimes for worse, will begin treatment by first prescribing pharmaceuticals, lubricants, and devices (e.g. vibrators). […] Unfortunately, there are no FDA approved treatment for DE and the drugs that doctors typically use have only anecdotal (here and there reports) of success. […] The most commonly used medications that doctors use that have only slight benefits are Cabergoline, Bupropion, Oxytocin, and Cyproheptadine. […] Sex therapists have reported good success rates using cognitive-behavioral techniques. […] The therapist begins with what the man can currently experience easily and suggests a slight alteration.
- #28 Delayed Ejaculation Treatment | Men’s Treatment – He Medical Clinichttps://www.hemedclinic.com/delayedejaculation
Delayed Ejaculation Treatment will depend on the underlying cause. This may include modifying masturbation behaviors, involving a partner in sex therapy to assess sex beliefs and determine if the threshold of stimulation can be met, a review of all medications taken, whether prescription or over-the-counter, and possibly testosterone replacement if required. […] Some treatments have been used to help DE, these includes : […] Low Testosterone can contribute to DE and low testosterone supplements could help fix your DE issue. […] Cyproheptadine (Periactin), which is an allergy medication […] Amantadine (Symmetrel), which is a drug used to treat Parkinsons disease […] Buspirone (Buspar), which is an antianxiety medication.
- #29 Psychosexual therapy for delayed ejaculation based on the Sexual Tipping Point model – Perelman – Translational Andrology and Urologyhttps://tau.amegroups.org/article/view/11164/html
The Sexual Tipping Point (STP) model is an integrated approach to the etiology, diagnosis and treatment of men with delayed ejaculation (DE), including all subtypes manifesting ejaculatory delay or absence. […] Assessment requires a thorough sexual history including inquiry into masturbatory methods to ascertain the information needed for proper diagnosis and treatment. […] The STP can be easily used to explain etiology and highlight treatment targets for patients. It helps clinicians disabuse patients erroneous binary beliefs. […] A safe effective medication for DE does not yet exist. When and if such a drug becomes available, this authors transdisciplinary perspective supports the appropriate use of that medication when combined with counseling. […] However, there are still numerous techniques, which can be combined to treat DE including and not limited to sex education, cognitive-behavioral therapy, mindfulness, psychodynamic exploration of underlying conflicts, and/or couples therapy.
- #29 Psychosexual therapy for delayed ejaculation based on the Sexual Tipping Point model – Perelman – Translational Andrology and Urologyhttps://tau.amegroups.org/article/view/11164/html
Help the man identify behaviors that enhance his ability to be immersed in excitation and minimize inhibiting thoughts, in order to reach ejaculation in his preferred manner. […] Current treatments usually emphasize integrating behavioral masturbatory retraining, within a nuanced sex therapy. […] Masturbation can serve as rehearsal for partnered sex. […] For both primary and secondary DE (as soon as therapeutically possible) obtain an agreement from the patient to temporarily refrain from ejaculating alone. […] The treatment approach recommended above is not merely for heterosexual men. […] The good success rates reported by sex therapists when treating DE should only be viewed as exploratory. […] There is no question that a drug treatment for men with severe DE would be beneficial (regardless of the degree of psychosocial-behavioral and cultural factor complications) although patients would benefit even more from medical treatment augmented by counseling.
- #30 Kelowna Delayed Ejaculation Treatment – Precision Sexual Health Clinichttps://precisionclinickelowna.ca/delayed-ejaculation/
These categories help in diagnosing an underlying cause and determining what might be the most effective treatment. A better erection can help make the overall treatment for delayed ejaculation more effective. […] DE treatment options include Shockwave Therapy, Injection Therapy, Sex Therapy, and Additional Therapies. […] If youâre taking medication that might be causing delayed ejaculation, reducing the dose of a medication or switching medications might fix the problem. […] Penile vacuum therapy and penile traction techniques may provide some benefit to treatment.
- #31https://www.practo.com/healthfeed/delayed-ejaculation-treatment-therapy-48947/post
Cognitive Behavioral Therapy (CBT): CBT can be beneficial for individuals with delayed ejaculation related to psychological issues. It aims to identify and modify negative thought patterns and behaviors that may contribute to the problem. […] Medication Review: In some cases, delayed ejaculation may be a side effect of certain medications, such as antidepressants. In such situations, a healthcare professional may consider adjusting the medication or exploring alternative treatments. […] Hormone Therapy: If hormonal imbalances are contributing to delayed ejaculation, hormone replacement therapy or other hormonal treatments may be considered to correct the issue. […] Decreasing Penile Sensation: Some individuals with delayed ejaculation may benefit from using desensitizing creams or condoms to reduce penile sensitivity and facilitate ejaculation.
- #32 Ejaculation Disorders – Types, Causes & Treatment | CCRM Fertilityhttps://www.ccrmivf.com/ejaculation-disorders/
It isnt necessary to treat retrograde ejaculation unless it is causing infertility and the goal is to achieve pregnancy. Retrograde ejaculation occurs in less than 2% of cases of infertility. Discontinuing use of medications that is causing the retrograde ejaculation is one form of treatment. There are also certain medications that can help the bladder neck muscle remain closed during ejaculation. […] For anejaculation caused by stress, the most common treatment is psychological counseling/therapy to address underlying causes. Treatment of anejaculation for infertility includes sperm retrieval and IUI or IVF. For men experiencing anejaculation as a result of spinal cord injury, a therapy known as penile vibratory stimulation can help the man to ejaculate.
- #33 How Do You Fix Retrograde Ejaculation? Causes & Treatmenthttps://www.medicinenet.com/how_do_you_fix_retrograde_ejaculation/article.htm
While retrograde ejaculation is not a life-threatening or disabling condition, it can cause male infertility. Therefore, treatment for retrograde ejaculation is only needed if you want to restore fertility. […] Medications can effectively treat retrograde ejaculation caused by mild nerve damage associated with diabetes, multiple sclerosis, and certain surgeries. However, drugs may not effectively treat permanent physical changes to reproductive anatomy caused by bladder neck surgery and transurethral resection of the prostate. […] Medications used to treat retrograde ejaculation work by keeping the bladder neck muscle closed during ejaculation. Common types include imipramine, midodrine, chlorpheniramine, ephedrine, pseudoephedrine, and phenylephrine. […] Certain prescribed medications may help enhance muscle tone and keep the bladder neck closed during ejaculation. These drugs include antihistamines, such as diphenhydramine, tricyclic antidepressants, and collagen injections into the bladder neck.
- #33 How Do You Fix Retrograde Ejaculation? Causes & Treatmenthttps://www.medicinenet.com/how_do_you_fix_retrograde_ejaculation/article.htm
Surgery is not a commonly recommended option and only prescribed when other methods are ineffective. Procedures typically involve reconstruction of bladder sphincter muscles. […] Infertility procedures may be a last resort if both drugs and surgery fail. While this type of procedure doesn’t cure the condition, it can help with conception. Sperm may be collected from the bladder or from a post-ejaculation urine sample and used for artificial fertilization.
- #34 Ejaculation disorders: Causes, diagnosis and treatment optionshttps://www.swissmedical.net/en/urology/erectile-dysfunction/ejaculation-disorders
Ejaculation disorders are sexual dysfunctions that affect a man’s ability to control ejaculation. These disorders can have a significant impact on quality of life and sexual satisfaction. […] Modern medical approaches offer effective diagnosis and treatment options to help affected men. […] Treatment: medication, behavioural therapy, psychological counselling. […] The treatment of ejaculation disorders depends on the specific disorder and its causes: […] Drug therapy: […] Premature ejaculation: Selective serotonin reuptake inhibitors (SSRIs), topical anaesthetics. […] Delayed ejaculation: adjustment or change of medication causing the disorder. […] Retrograde ejaculation: Alpha-blockers or other medications to improve bladder neck closure. […] Behavioural therapy: […] Techniques: start-stop technique, squeeze technique to delay ejaculation.
- #35 Retrograde Ejaculation Guide: Causes, Symptoms and Treatment Optionshttps://www.drugs.com/health-guide/retrograde-ejaculation.html
Retrograde ejaculation requires treatment because it interferes with fertility. This treatment varies depending on the cause. If your retrograde ejaculation is a side effect of medication, your doctor probably will switch you to a drug that does not affect ejaculation. […] In cases of retrograde ejaculation, three of the more commonly used assisted fertilization procedures are: Intrauterine insemination (using a small catheter to put washed sperm inside your partner’s uterus at the time of ovulation), In-vitro fertilization (incubating eggs and sperm together in the laboratory to produce fertilization), Intracytoplasmic sperm injection (injecting a single sperm into your partner’s egg to cause fertilization). […] Simple therapies have a good chance of decreasing retrograde ejaculation enough to allow conception. In men who do not respond to medication, fathering a child may still be possible with the help of assisted fertilization procedures.
- #36 Anejaculation: Causes, Symptoms, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/23371-anejaculation
Anejaculation is a type of male sexual dysfunction that can affect ones ability to enjoy sex. It can also lead to male infertility. […] Anejaculation doesn’t cause any long-term problems. Some people don’t seek or want treatment. Treatment (when desired) depends on the underlying cause. Psychotherapy (talk therapy), sex therapy and anti-anxiety medications can ease anxiety and stress that cause situational anejaculation. […] A urologist or reproductive medicine specialist can use different methods to retrieve sperm from your testicles. Your healthcare provider then uses infertility treatments to fertilize eggs with your extracted sperm. Examples include intrauterine insemination (IUI) or in vitro fertilization (IVF). […] Penile vibratory stimulation (PVS): You apply a specially designed vibrator to the tip of your penis. Sensory nerves carry the vibrations to your spinal cord, causing ejaculation. As many as 6 in 10 men with anejaculation ejaculate with PVS. This therapy may take place at home or your providers office.
- #36 Anejaculation: Causes, Symptoms, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/23371-anejaculation
Electroejaculation: If PVS doesn’t work, your healthcare provider may insert a probe into your rectum to directly stimulate the sensory nerves near your prostate. The probe sends mild electrical pulses that cause you to orgasm and ejaculate. This procedure may take place under general anesthesia (you’re asleep). About 9 in 10 men ejaculate with this method, but sperm quality may be poor at first. You may need to undergo the procedure several times to get a good sperm sample. […] Sperm extraction: During microscopic testicular sperm extraction, your provider surgically removes a small amount of tissue from your testicles and then extracts sperm from it. You’re asleep for this procedure. […] There are therapies that can help. It’s especially critical to talk to your provider if you want to conceive a child. There are procedures and fertility treatments that can help you start a family.
- #37 Inability to Ejaculate – Men’s Health Issues – Merck Manual Consumer Versionhttps://www.merckmanuals.com/home/men-s-health-issues/sexual-function-and-dysfunction-in-men/inability-to-ejaculate
Inability to ejaculate (anejaculation) is usually caused by inability to reach orgasm (anorgasmia). […] Treatment of anejaculation depends on the cause and may include stopping any medications that may be causing the problem, engaging in psychotherapy, or helping trigger ejaculation using oral medications such as pseudoephedrine and/or imipramine. […] If the goal of therapy is to obtain semen for insemination, the man can use a penile vibrator or his doctor can apply an electric signal to the rectum to activate the nerves responsible for ejaculation (electroejaculation therapy). […] There is no treatment when anejaculation is due to removal of the prostate and seminal vesicles. […] In infertile patients who cannot produce semen, sperm can be directly extracted from the testicles and used for assisted reproduction, such as in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI).
- #38 Ejaculatory Dysfunction | Urology Associates | Denver Metrohttps://www.denverurology.com/mens-fertility-sexual-health/ejaculatory-dysfunction/
Ejaculatory dysfunction is the inability of a man to efficiently ejaculate semen from the penis at the moment of sexual climax. […] Treatments for ejaculatory dysfunction include medications, behavioral therapy (for premature ejaculation) and sometimes surgery. […] Medications, physical therapy and psychotherapy are tools for treating PE. The goal of treatment is to decrease penile sensitivity and increase the patients control over his behavioral responses. […] While medications may provide temporary relief, behavioral therapy is the only way to cure premature ejaculation. […] Psychotherapy can deal with underlying mental health and psychological issues. […] A few medications are also used to treat delayed ejaculation. […] The most common treatment for anejaculation is psychological counseling to address underlying causes and sexual therapy.
- #39https://connect.asrm.org/smru/blogs/robert-coward-md/2019/01/31/treatment-options-for-patients-with-ejaculatory-dy
Treatment Options for Patients with Ejaculatory Dysfunction […] Ejaculatory dysfunction can be characterized as premature, delayed, or absent ejaculation. […] Retrograde ejaculation should be ruled out as a first step in the workup of ejaculatory dysfunction, as treatment is often successful without invasive procedures. […] Retrograde ejaculation can occasionally be normalized with correction of the underlying problem such as treatment of diabetes. […] Anejaculation can occur with spinal cord injury, erectile dysfunction, hormone problems, or emotional inability. […] Treatment options to retrieve sperm for men with infertility due to anejaculation or anorgasmia include two different neurostimulatory methods. […] Penile vibratory stimulation (PVS) is the recommended first-line treatment for anejaculation because it is simple, non-invasive, cost-effective, and successful in approximately 75% of cases.
- #39https://connect.asrm.org/smru/blogs/robert-coward-md/2019/01/31/treatment-options-for-patients-with-ejaculatory-dy
If PVS is unsuccessful or not desired, electroejaculation is more invasive alternative treatment of anejaculation that is almost uniformly successful. […] When treatments with medications or neurostimulatory methods for ejaculatory dysfunction fail, there always remains an option for surgical sperm extraction. […] In summary, ejaculatory dysfunction is a common problem manifested in a variety of different disorders.
- #40 Male Problems & Treatments | San Diego Sexual Medicinehttps://www.sdsm.info/male-problems-treatments
First-time therapies include hormone therapy (androgens), dopamine agonist therapy, oral phosphodiesterase type-5 inhibitors and vacuum erection device therapy. […] Second-time therapies include penile self-injection therapy and intra-urethral alprostadil therapy. […] Third-line therapies include surgery for placement of penile prosthesis, surgery for penile revascularization, and surgery for correction of penile curvature. […] In addition to treating symptoms, San Diego Sexual Medicine offers regenerative therapies including genuine shockwave therapy and platelet rich plasma treatment. […] The most logical, efficacious way to restore sexual function in men with sexual health problems is to manage the sexual problem with multiple disciplines, proceed in a step-care process and, whenever possible, to engage the partner.
- #41 New technologies developed for treatment of premature ejaculation | International Journal of Impotence Researchhttps://www.nature.com/articles/s41443-024-00875-w
Premature ejaculation (PE), lifelong and acquired, is the most common male sexual disorder, with serious impacts on the patient and his partners quality of life, sexual well-being, and psychosocial health. The most popular treatment options are on-demand topical anesthetics and off-label daily or on-demand selective serotonin reuptake inhibitors (SSRIs), followed by behavioral therapy. While SSRI treatments are reportedly safe, they are associated with limited efficacy and provide only a temporary delay in ejaculation latency time. The majority of PE patients are dissatisfied with SSRIs; thus, adherence to on-demand or daily SSRI treatments is low. […] A definitive cure for PE is still elusive, and ongoing research is focused on identifying the optimal treatment for this condition. Consequently, in response to the unmet need for PE therapy, new technologies are currently under development.
- #41 New technologies developed for treatment of premature ejaculation | International Journal of Impotence Researchhttps://www.nature.com/articles/s41443-024-00875-w
Behavioral therapy, specifically sex therapy, represents a treatment with fewer side effects and lower costs. Its goal is to enhance self-confidence and alleviate anxiety and depression by systematically training men to acquire sexual skills that can extend ejaculation time. In the short term, behavioral therapy can yield success rates ranging from 45% to 65% of patients, but its long-term effects remain uncertain. […] This study presents a novel approach to addressing lifelong PE through the extension of on-demand coital duration, achieved via electric stimulation of the ejaculation muscles using the In2 patch. This method holds promise as a potential on-demand, non-invasive, and drug-free treatment for PE. […] This study introduces an innovative approach to addressing lifelong PE by extending on-demand coital duration through electric stimulation of the ejaculation muscles using the In2 patch. This method shows promise as a potential on-demand, non-invasive, and drug-free treatment for PE.
- #41 New technologies developed for treatment of premature ejaculation | International Journal of Impotence Researchhttps://www.nature.com/articles/s41443-024-00875-w
The initial outcomes of TPTNS in treating PE appear conflicting, highlighting the need for randomized controlled studies involving large patient cohorts. […] In recent years, a new approach to treating PE has emerged, involving the use of a masturbation aid device in conjunction with behavioral techniques. […] Currently, the standards of care in PE treatment are mainly SSRIs and topical anesthetics. However, the available drug treatments for PE come with limited effectiveness, a range of adverse effects, and a high rate of discontinuation. A definitive cure for PE, or at least therapies allowing for spontaneity during intercourse, remain elusive. Encouragingly, data from studies utilizing newly developed technological techniques and medical devices in PE treatment show promise. Solutions that are drug-free, entail minimal adverse effects, and permit spontaneity during intercourse are on the horizon. However, additional clinical studies would be beneficial in confirming the effectiveness of these therapies, potentially establishing them as possible alternatives to pharmacological PE treatments.
- #42 How Shockwave Therapy Can Treat Premature Ejaculation | Center For Urologyhttps://centerforurology.org/how-shockwave-therapy-can-treat-premature-ejaculation/
For men living with erectile dysfunction (ED), a newer treatment known as shockwave therapy has been delivering results. […] New research shows that this noninvasive, painless treatment can also help with premature ejaculation. […] At the Center for Urology in Altamonte Springs, Florida, Abraham Woods, MD, offers shockwave therapy to help men struggling with premature ejaculation. […] Fortunately, with shockwave therapy, Dr. Woods can address the ED and the premature ejaculation that often accompanies it. […] If you live with both ED and premature ejaculation, Dr. Woods may recommend shockwave therapy for you. […] This helps you get and maintain an erection. […] If you’re dealing with premature ejaculation and especially if you also struggle with ED don’t hesitate to talk to Dr. Woods. […] He applies his extensive expertise and compassionate care in helping men improve their sexual wellness.
- #43 Delayed ejaculation: Causes, treatment, and outlookhttps://www.medicalnewstoday.com/articles/284679
Some medications may help improve the symptoms of delayed ejaculation when used off-label, but none have been specifically approved to treat it yet. […] Successful treatment of delayed ejaculation depends on the cause of the delayed ejaculation and the type of treatment. Each individual will have different needs and outcomes.