Ospa wietrzna
Zapobieganie i profilaktyka

Ospa wietrzna (varicella) jest wysoce zakaźną chorobą wirusową wywoływaną przez wirus Varicella-Zoster (VZV). Profilaktyka opiera się przede wszystkim na szczepieniach, które wykazują skuteczność na poziomie 80-94% po pełnym schemacie (dwie dawki: pierwsza w wieku 12-15 miesięcy, druga między 4. a 6. rokiem życia; u osób powyżej 13. roku życia dwie dawki w odstępie 4-8 tygodni). Szczepionka zawiera żywy, atenuowany wirus i jest dostępna w formie monowalentnej lub skojarzonej MMRV. Szczepienia znacząco zmniejszyły zachorowalność, hospitalizacje i zgony o 90-97%. Szczególnie zalecane są dla grup wysokiego ryzyka, w tym kobiet ciężarnych planujących ciążę (szczepienie co najmniej miesiąc przed), osób z obniżoną odpornością, pracowników ochrony zdrowia oraz osób mających kontakt z małymi dziećmi. Przeciwwskazania obejmują ciążę, immunosupresję, aktywną gorączkę oraz reakcje alergiczne na składniki szczepionki.

Profilaktyka ospy wietrznej

Ospa wietrzna (varicella) jest wysoce zakaźną chorobą wirusową wywoływaną przez wirus ospy wietrznej i półpaśca (Varicella-Zoster Virus, VZV). Profilaktyka tej choroby ma kluczowe znaczenie, szczególnie dla osób z grup wysokiego ryzyka ciężkiego przebiegu infekcji, takich jak kobiety ciężarne, noworodki, osoby z obniżoną odpornością oraz dorośli, u których choroba często przebiega ciężej niż u dzieci. Stosowanie odpowiednich strategii profilaktycznych może skutecznie zapobiegać zachorowaniom lub łagodzić przebieg choroby.123

Szczepienie przeciwko ospie wietrznej

Szczepienie jest najbardziej efektywną metodą zapobiegania ospie wietrznej. Szczepionka przeciwko ospie wietrznej zawiera żywy, atenuowany (osłabiony) wirus i zapewnia wysoki poziom ochrony przed zachorowaniem. Skuteczność szczepionki w zapobieganiu ospie wietrznej wynosi od 80% do 94% po podaniu pełnego schematu szczepienia, przy czym nawet w przypadku zachorowania u osób zaszczepionych przebieg choroby jest zazwyczaj znacznie łagodniejszy, z mniejszą liczbą zmian skórnych i niższą gorączką lub jej brakiem.1245

Od czasu wprowadzenia powszechnych szczepień przeciwko ospie wietrznej w latach 90. XX wieku, liczba przypadków zachorowań, hospitalizacji i zgonów związanych z tą chorobą znacząco spadła. Według danych z różnych krajów, szczepienia przyczyniły się do redukcji zachorowań o 90-97%.367

Schemat szczepień przeciwko ospie wietrznej

Schemat szczepienia różni się w zależności od wieku, ale generalnie obejmuje dwie dawki szczepionki:

  • Dzieci w wieku 12-15 miesięcy powinny otrzymać pierwszą dawkę szczepionki
  • Druga dawka zalecana jest między 4. a 6. rokiem życia
  • Dzieci, młodzież i dorośli powyżej 13. roku życia, którzy nie chorowali na ospę wietrzną i nie byli wcześniej szczepieni, powinni otrzymać dwie dawki szczepionki w odstępie co najmniej 28 dni (zalecany odstęp 4-8 tygodni)2589

Szczepionka przeciwko ospie wietrznej może być podawana jako szczepionka monowalentna (zawierająca tylko antygen ospy wietrznej) lub w postaci szczepionki skojarzonej MMRV, która zawiera również komponenty przeciwko odrze, śwince i różyczce. Szczepionka MMRV jest zazwyczaj stosowana u dzieci, natomiast u osób powyżej 13. roku życia zaleca się stosowanie szczepionki monowalentnej.1011

Grupy wysokiego ryzyka – zalecenia szczepienne

Szczepienie przeciwko ospie wietrznej jest szczególnie zalecane dla następujących grup osób, jeśli nie posiadają one odporności na wirusa VZV:48

  • Pracownicy ochrony zdrowia
  • Nauczyciele i personel placówek edukacyjnych
  • Osoby pracujące w żłobkach i przedszkolach
  • Osoby z otoczenia pacjentów z obniżoną odpornością
  • Kobiety w wieku rozrodczym planujące ciążę (szczepienie należy wykonać co najmniej miesiąc przed planowaną ciążą)
  • Osoby podróżujące międzynarodowo
  • Personel wojskowy
  • Osoby dorosłe mieszkające z małymi dziećmi121013

Przeciwwskazania do szczepienia

Ponieważ szczepionka przeciwko ospie wietrznej zawiera żywy, atenuowany wirus, istnieją pewne przeciwwskazania do jej stosowania:1415

  • Ciąża – kobiety ciężarne nie powinny być szczepione przeciwko ospie wietrznej, a po szczepieniu należy unikać zajścia w ciążę przez co najmniej miesiąc
  • Osoby z obniżoną odpornością (ciężkie niedobory odporności, pacjenci po przeszczepach, osoby otrzymujące wysokie dawki kortykosteroidów, chemioterapię lub radioterapię)
  • Osoby z umiarkowaną lub ciężką chorobą przebiegającą z gorączką
  • Osoby z reakcją alergiczną na wcześniejszą dawkę szczepionki lub jej składniki1617

Działania niepożądane po szczepieniu

Szczepionka przeciwko ospie wietrznej jest uznawana za bezpieczną. Najczęstsze działania niepożądane są zazwyczaj łagodne i obejmują:1415

  • Ból, zaczerwienienie lub obrzęk w miejscu wstrzyknięcia
  • Łagodna wysypka (zwykle około pięciu wykwitów)
  • Rzadko może wystąpić gorączka16

Profilaktyka poekspozycyjna ospy wietrznej

Profilaktyka poekspozycyjna (PEP – Post-Exposure Prophylaxis) ma na celu zapobieganie rozwojowi choroby lub złagodzenie jej przebiegu u osób, które miały kontakt z osobą chorą na ospę wietrzną lub półpasiec. PEP jest szczególnie ważna dla osób z grup wysokiego ryzyka ciężkiego przebiegu choroby.1819

Szczepienie poekspozycyjne

Szczepienie poekspozycyjne jest zalecane dla niezaszczepionych, wrażliwych osób po kontakcie z ospą wietrzną, jeśli nie ma przeciwwskazań do szczepienia. Aby było skuteczne, szczepionkę należy podać jak najszybciej po ekspozycji, najlepiej w ciągu 3-5 dni (optymalnie w ciągu 72 godzin).182021

Badania wykazały, że szczepienie poekspozycyjne może:2223

  • Zapobiec rozwojowi choroby w około 70-80% przypadków, jeśli zostanie zastosowane w ciągu 3 dni od ekspozycji
  • Złagodzić przebieg choroby, nawet jeśli nie zapobiegnie całkowicie infekcji
  • Ograniczyć dalszą transmisję wirusa242526

Szczepienie poekspozycyjne jest szczególnie zalecane dla osób z bezpośredniego kontaktu domowego z chorym, osób przebywających w placówkach opiekuńczych, oświatowych oraz placówkach ochrony zdrowia.2127

Immunoglobulina przeciwko ospie wietrznej i półpaśćowi

Dla osób, u których szczepienie jest przeciwwskazane, alternatywną metodą profilaktyki poekspozycyjnej jest podanie immunoglobuliny przeciwko ospie wietrznej i półpaśćowi (VZIG – Varicella-Zoster Immune Globulin). VZIG zawiera przeciwciała przeciwko wirusowi VZV i może pomóc w zapobieganiu lub łagodzeniu przebiegu choroby.221815

VZIG jest zalecana dla następujących grup osób po ekspozycji na wirusa ospy wietrznej:2822

  • Osoby z obniżoną odpornością bez dowodów na przebycie ospy wietrznej lub brak szczepienia
  • Kobiety ciężarne bez odporności przeciwko VZV
  • Noworodki, których matki zachorowały na ospę wietrzną w okresie od 7 dni przed do 7 dni po porodzie
  • Wcześniaki urodzone przed 28. tygodniem ciąży lub z masą urodzeniową poniżej 1000 g, niezależnie od statusu immunologicznego matki
  • Noworodki hospitalizowane, które miały kontakt z ospą wietrzną293031

VZIG powinna być podana jak najszybciej po ekspozycji, najlepiej w ciągu 96 godzin (4 dni), choć w niektórych przypadkach może być skuteczna nawet do 10 dni po ekspozycji.283222

Profilaktyka z użyciem leków przeciwwirusowych

W niektórych przypadkach, jako alternatywa dla VZIG lub w sytuacjach, gdy VZIG nie jest dostępna, można rozważyć profilaktyczne podanie leków przeciwwirusowych, takich jak acyklowir czy walacyklowir. Leki te mogą zapobiec rozwojowi choroby lub złagodzić jej przebieg, jeśli zostaną podane odpowiednio wcześnie po ekspozycji.332834

Profilaktyka przeciwwirusowa jest szczególnie zalecana dla:2935

  • Osób z obniżoną odpornością po ekspozycji na VZV
  • Kobiet ciężarnych bez odporności przeciwko VZV, które miały kontakt z ospą wietrzną
  • Noworodków w grupie wysokiego ryzyka
  • Osób, u których nie można zastosować VZIG lub szczepienia3637

Badania wykazały, że podanie acyklowiru w dawce profilaktycznej w okresie inkubacji ospy wietrznej (około 9 dni po ekspozycji) może skutecznie zapobiec lub zmodyfikować przebieg kliniczny choroby.3334

Profilaktyka w placówkach ochrony zdrowia

Zapobieganie szerzeniu się ospy wietrznej w placówkach ochrony zdrowia jest szczególnie ważne ze względu na obecność osób z grup wysokiego ryzyka ciężkiego przebiegu choroby.2038

Zalecenia dla personelu medycznego

Wszyscy pracownicy ochrony zdrowia powinni posiadać udokumentowane dowody odporności przeciwko ospie wietrznej, takie jak:204

  • Udokumentowana historia przebycia ospy wietrznej
  • Potwierdzenie laboratoryjne przebycia ospy wietrznej lub obecności przeciwciał przeciwko VZV
  • Dokumentacja potwierdzająca otrzymanie dwóch dawek szczepionki przeciwko ospie wietrznej134

Pracownicy ochrony zdrowia, którzy nie posiadają odporności przeciwko ospie wietrznej, powinni zostać zaszczepieni, o ile nie ma przeciwwskazań do szczepienia.439

Postępowanie w przypadku ekspozycji w placówce medycznej

W przypadku ekspozycji na ospę wietrzną w placówce ochrony zdrowia zaleca się następujące działania:2022

  • Identyfikacja wszystkich osób, które miały kontakt z chorym
  • Ocena statusu immunologicznego osób eksponowanych
  • Profilaktyka poekspozycyjna dla podatnych pracowników i pacjentów:
    • Szczepienie dla osób bez przeciwwskazań, w ciągu 3-5 dni od ekspozycji
    • VZIG dla osób z przeciwwskazaniami do szczepienia, w ciągu 96 godzin od ekspozycji
  • Obserwacja osób eksponowanych przez 21 dni (okres inkubacji ospy wietrznej)3140

Izolacja pacjentów z ospą wietrzną

Pacjenci z podejrzeniem lub potwierdzeniem ospy wietrznej powinni być izolowani, aby zapobiec transmisji wirusa:2041

  • Pacjenci powinni być umieszczeni w sali z podciśnieniem (izolacja powietrzno-kropelkowa)
  • Należy stosować standardowe środki ostrożności oraz izolację powietrzno-kropelkową i kontaktową
  • Personel opiekujący się pacjentem powinien posiadać odporność przeciwko ospie wietrznej
  • Izolacja powinna być utrzymana do momentu, gdy wszystkie zmiany skórne pokryją się strupami3841

Profilaktyka w społeczności i placówkach oświatowych

Zapobieganie rozprzestrzenianiu się ospy wietrznej w społeczności i placówkach oświatowych wymaga podejmowania odpowiednich działań, zarówno na poziomie indywidualnym, jak i zbiorowym.4243

Zasady higieny i izolacji

Przestrzeganie zasad higieny pomaga ograniczyć rozprzestrzenianie się wirusa ospy wietrznej:54445

  • Częste mycie rąk wodą z mydłem, szczególnie po kaszlu, kichaniu lub korzystaniu z toalety
  • Unikanie dotykania oczu, nosa i ust, aby zminimalizować ryzyko przeniesienia wirusa z zanieczyszczonych powierzchni na błony śluzowe
  • Zakrywanie ust i nosa podczas kaszlu i kichania
  • Regularna dezynfekcja często dotykanych powierzchni, takich jak klamki, włączniki światła i blaty4446

Osoby chore na ospę wietrzną powinny być izolowane do czasu, gdy wszystkie wykwity skórne pokryją się strupami, co zwykle następuje po 5-7 dniach od pojawienia się wysypki. Dzieci z ospą wietrzną nie powinny uczęszczać do szkoły, przedszkola czy żłobka w okresie zakaźności.432547

Postępowanie podczas ognisk epidemicznych

W przypadku wystąpienia ogniska ospy wietrznej w placówce oświatowej lub innej instytucji, zaleca się następujące działania:2148

  • Szybka identyfikacja i izolacja osób chorych
  • Powiadomienie rodziców/opiekunów oraz odpowiednich służb sanitarnych
  • Identyfikacja osób, które miały kontakt z chorymi
  • Szczepienie poekspozycyjne podatnych osób, które miały kontakt z chorymi, w ciągu 3-5 dni od ekspozycji
  • Szczególna ochrona osób z grup wysokiego ryzyka ciężkiego przebiegu choroby4950

Zalecenia dla kobiet w ciąży

Kobiety ciężarne są szczególnie narażone na powikłania związane z ospą wietrzną, zwłaszcza w trzecim trymestrze ciąży. Zakażenie w tym okresie może prowadzić do zapalenia płuc u matki, a zakażenie w pierwszych 20 tygodniach ciąży wiąże się z ryzykiem zespołu ospy wietrznej wrodzonej u płodu.3551

Zalecenia dla kobiet ciężarnych obejmują:1535

  • Kobiety planujące ciążę, które nie chorowały na ospę wietrzną i nie były szczepione, powinny otrzymać szczepionkę przeciwko ospie wietrznej przed zajściem w ciążę (co najmniej miesiąc przed)
  • Kobiety ciężarne powinny unikać kontaktu z osobami chorymi na ospę wietrzną lub półpasiec
  • W przypadku ekspozycji na ospę wietrzną, ciężarna bez odporności powinna jak najszybciej skontaktować się z lekarzem
  • W zależności od lokalnych zaleceń, po ekspozycji może być zalecane podanie VZIG lub leków przeciwwirusowych525332

Szczepionki przeciwko półpaśćowi

Wirus ospy wietrznej, po wyleczeniu pierwotnej infekcji, pozostaje w organizmie w formie latentnej i może się reaktywować w późniejszym okresie życia, powodując półpasiec (herpes zoster). Dla osób starszych i z grup ryzyka dostępne są szczepionki przeciwko półpaśćcowi, które zmniejszają ryzyko wystąpienia tej choroby.5455

Szczepionka przeciwko półpaśćcowi jest zalecana dla:2555

  • Osób w wieku 50 lat i starszych
  • Osób z obniżoną odpornością w wieku 18 lat i starszych, zgodnie z lokalnymi zaleceniami
  • Osób ze schorzeniami przewlekłymi zwiększającymi ryzyko półpaśca54

Szczepionka przeciwko półpaśćcowi może znacząco zmniejszyć ryzyko wystąpienia półpaśca oraz neuralgii popółpaścowej, która jest jednym z najpoważniejszych powikłań tej choroby.55

Podsumowanie profilaktyki ospy wietrznej

Profilaktyka ospy wietrznej opiera się na kilku kluczowych strategiach, które pomagają zapobiegać zachorowaniom lub łagodzić przebieg choroby:1356

  • Szczepienie przeciwko ospie wietrznej jest najskuteczniejszą metodą zapobiegania chorobie. Zalecane jest dla wszystkich dzieci, młodzieży i dorosłych, którzy nie przebyli ospy wietrznej i nie byli wcześniej szczepieni
  • Profilaktyka poekspozycyjna, obejmująca szczepienie, podanie immunoglobuliny VZIG lub leków przeciwwirusowych, powinna być rozważona dla osób z grup wysokiego ryzyka po kontakcie z ospą wietrzną
  • Przestrzeganie zasad higieny i izolacja osób chorych pomagają ograniczyć rozprzestrzenianie się wirusa w społeczności
  • Szczególną ochroną należy objąć osoby z grup wysokiego ryzyka ciężkiego przebiegu choroby, takie jak kobiety ciężarne, noworodki i osoby z obniżoną odpornością5758

Dzięki powszechnym szczepieniom i odpowiednim działaniom profilaktycznym, liczba przypadków ospy wietrznej i związanych z nią powikłań znacząco spadła w ostatnich dekadach. Jednak nadal ważne jest kontynuowanie tych działań, aby chronić osoby podatne na zakażenie, zwłaszcza te, które są narażone na ciężki przebieg choroby.5960

Kolejne rozdziały

Zapraszamy do dalszego czytania naszego leksykonu.

Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.

  1. 09.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Chickenpox: Causes, Symptoms, Treatment & Prevention
    https://my.clevelandclinic.org/health/diseases/4017-chickenpox
    Chickenpox, also called varicella-zoster, produces a red rash that blisters, then scabs over. Its very contagious and spreads through bodily fluids and bodily contact. You can prevent chickenpox with a vaccine. […] But its much less common today because theres a vaccine that protects you from it. […] Today, most children receive a vaccine against chickenpox as part of their routine immunization schedule. […] Adults who havent had chickenpox should also get the vaccine. If youre 13 or older and never got the vaccine, you should get two doses at least 28 days apart. […] Vaccination is over 90% effective at preventing chickenpox. Since 1995, the vaccine has prevented at least 91 million cases of chickenpox. […] The chickenpox vaccine is over 90% effective at preventing this once-common childhood illness. You can still get chickenpox if you dont get the vaccine even as an adult. Talk to your healthcare provider about getting vaccinated if you never had chickenpox. While most cases arent serious, you can reduce the risk of getting the virus by receiving a vaccine. Most children receive the chickenpox vaccine as part of their childhood immunizations.
  • #2 Patient education: Chickenpox prevention and treatment (Beyond the Basics) – UpToDate
    https://www.uptodate.com/contents/chickenpox-prevention-and-treatment-beyond-the-basics/print
    Patient education: Chickenpox prevention and treatment (Beyond the Basics) […] Today, thanks to the advent of the varicella vaccine, chickenpox is relatively rare. This article will discuss the prevention and treatment of chickenpox. […] The chickenpox vaccine protects against infection in 80 to 90 percent of those who are vaccinated. […] Vaccination in children — In the United States, the varicella vaccine is recommended for all children at 12 through 15 months of age. A second dose is recommended at 4 to 6 years of age. […] In contrast, adults who do not have immunity to chickenpox can benefit from being vaccinated. […] Experts recommend varicella vaccination for adults without immunity, especially those who are at risk of exposure to chickenpox and those who are in contact with people who are at risk for severe chickenpox infection.
  • #3 About Chickenpox | Chickenpox (Varicella) | CDC
    https://www.cdc.gov/chickenpox/about/index.html
    The best way to prevent chickenpox is to get the chickenpox vaccine. […] The chickenpox vaccine prevents almost all cases of severe illness. Since the chickenpox vaccination program began in the United States, there has been over 97% decrease in chickenpox cases. Hospitalizations and deaths have become rare. […] The best way to protect infants and children against chickenpox is to get them vaccinated.
  • #4 Chickenpox Treatment & Management: Approach Considerations, Treatment in Healthy Children, Treatment in Immunocompetent Adults
    https://emedicine.medscape.com/article/1131785-treatment
    The varicella vaccine is proven to be safe, effective, and cost-efficient for healthy children, adolescents, and adults. Breakthrough cases of MVLS are notably less severe than infections with wild-type varicella. […] According to the Centers for Disease Control and Prevention (CDC), all healthy children and susceptible individuals should receive two doses of the live attenuated varicella vaccine, as outlined in the CDC’s Child and Adolescent Immunization Schedule by Age. Vaccination is particularly important for individuals of reproductive age, those at high risk for exposure, and those who have contact with individuals at higher risk for severe disease. This includes healthcare professionals, educators, childcare workers, and residents and staff of nursing homes or other institutional settings such as correctional facilities.
  • #5 Chickenpox Prevention: How to Avoid the Varicella-Zoster Virus
    https://www.healthline.com/health/chicken-pox-prevention
    Chickenpox is preventable through vaccination. In fact, receiving two doses of the chickenpox vaccine is about 94 percent effective at preventing the disease. […] Chickenpox can be prevented through vaccination, which is recommended for: all children, adolescents, adults who arent already immune to chickenpox. […] Two doses of the vaccine are needed. […] Children should receive the chickenpox vaccine as part of their regular vaccine schedule. The first dose should be received between 12 and 15 months of age. The second dose should be received between 4 and 6 years of age. […] Adolescents or adults who arent vaccinated should receive two doses of the vaccine spaced one month apart. […] In addition to vaccination, you can help prevent the spread of chickenpox by practicing good hygiene and washing your hands frequently. Reduce your exposure to people who have chickenpox.
  • #6 Chickenpox – Wikipedia
    https://en.wikipedia.org/wiki/Chickenpox
    Chickenpox can be prevented by vaccination. The varicella vaccine is recommended in many countries. Immunization within three days following household contact reduces infection rates and severity in children. […] Since its introduction in 1995 in the United States, the varicella vaccine has resulted in a decrease in the number of cases and complications from the disease. […] The vaccine is part of the routine immunization schedule in the US. Some European countries include it as part of universal vaccinations in children, but not all countries provide the vaccine.
  • #7 Immunizations: Chickenpox (Varicella) | Wisconsin Department of Health Services
    https://www.dhs.wisconsin.gov/immunization/varicella.htm
    A vaccine can prevent chickenpox. The best way to prevent chickenpox is to get the vaccine! […] A vaccine is your best protection against catching chickenpox. The CDC recommends two doses of the varicella vaccine for: Children, Adolescents, Adults who never had chickenpox and were never vaccinated. […] Chickenpox vaccine is very safe and effective at preventing the disease. Most people who get the vaccine won’t get chickenpox. If a vaccinated person does get chickenpox, the symptoms are usually milder with fewer or no blisters (they may have just red spots) and mild or no fever. […] The chickenpox vaccine prevents almost all cases of severe illness. Since the varicella vaccination program began in the United States, there has been over 90% decrease in chickenpox cases, hospitalizations, and deaths.
  • #8 Chickenpox – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/chickenpox/symptoms-causes/syc-20351282
    The chickenpox vaccine is a safe way to prevent this illness and the other health problems that can happen during it. […] The chickenpox vaccine, also called the varicella vaccine, is the best way to prevent chickenpox. In the United States, experts from the CDC report that two doses of the vaccine prevent illness over 90% of the time. Even if you get chickenpox after receiving the vaccine, your symptoms may be much milder. […] In the United States, children receive two doses of the varicella vaccine: the first between ages 12 and 15 months and the second between ages 4 and 6 years. This is part of the routine vaccination schedule for children. […] People age 13 or older who haven’t been vaccinated should receive two catch-up doses of the vaccine at least four weeks apart. It’s even more important to get the vaccine if you have a higher risk of getting exposed to chickenpox. This includes health care workers, teachers, child-care employees, international travelers, military personnel, adults who live with young children and all nonpregnant women of childbearing age.
  • #9
    https://www.healthychildren.org/English/health-issues/vaccine-preventable-diseases/Pages/Varicella-ChickenPox.aspx
    The chickenpox vaccine is recommended for all children who have not had the disease. Most people who get the vaccine are protected for life and won’t get chickenpox. […] Children receive two doses of chickenpox vaccine to ensure the broadest protection. […] The first dose is given at 12 to 15 months of age. […] The second dose is given between 4 and 6 years old. They can receive their second dose earlier if it has been at least three months since the first dose. […] Children 13 years and older who have never had chickenpox or the vaccine should get two doses, spaced at least 28 days apart. […] If you plan to become pregnant and have not had chickenpox or the vaccine, get the vaccine before pregnancy. […] Remember Chickenpox spreads very easily. The infection can be serious, especially for young children. Most people who get both doses of the vaccine will not get chickenpox. Getting two doses is the best way to help protect your child and others.
  • #10 Varicella (chickenpox) | The Australian Immunisation Handbook
    https://immunisationhandbook.health.gov.au/contents/vaccine-preventable-diseases/varicella-chickenpox
    Vaccination for certain groups of people is funded under the National Immunisation Program. […] Varicella-containing vaccine is recommended for children at 18 months of age as MMRV (measles-mumps-rubella-varicella) vaccine. […] All adolescents ≥14 years of age and adults should have either: documented evidence of 2 doses of varicella-containing vaccine given at least 4 weeks apart, or a history of varicella infection. […] Non-immune people ≥14 years of age can receive monovalent varicella vaccine. MMRV is not recommended in this age group. […] Varicella vaccine is recommended for household contacts of people who are immunocompromised. […] Vaccination reduces the likelihood of varicella infection after exposure, especially moderate to severe disease. It also provides long-term protection. Vaccinating exposed people during outbreaks prevents further cases and controls outbreaks. […] If varicella vaccine is not contraindicated, it can be offered to non-immune age-eligible children and adults who have had a significant exposure to varicella or herpes zoster and want protection against primary infection with varicella.
  • #11 Chickenpox: Symptoms, treatment, stages, and causes
    https://www.medicalnewstoday.com/articles/239450
    There is no cure for chickenpox, but a vaccine is available for VZV. Today, the chickenpox vaccine is about 90% effective at preventing the disease for most people. […] People should avoid close contact with people known to have chickenpox, avoid sharing objects with them, isolate any household members with chickenpox from others, and disinfect surfaces an infected person may have touched. […] There are two types of the VZV vaccine: […] Varivax: This is only the chickenpox vaccine. Children get two shots, with the first dose between 12-15 months and a second time between 4-6 years. […] ProQuad: This is a combination vaccine that also contains vaccines for measles, mumps, and rubella. Healthcare professions call it MMRV. Children get this vaccine on the same schedule as Varivax, but it can only be given to children between 12 months and age 12.
  • #12
    https://www.ncid.sg/Health-Professionals/Diseases-and-Conditions/Pages/Chickenpox.aspx
    Several vaccines are available for use in the prevention of chickenpox. They are all live attenuated viral vaccines and should not be used in pregnant and severely immunocompromised individuals. […] For children (13 years) 2 doses are recommended. 1st dose at age 12 months to 15 months and 2nd dose at age 4 years to 6 years. […] For adults and those 13 years old, a two dose regimen (4 weeks to 6 weeks apart) is recommended. […] The vaccine is recommended for all those who are non-immune to chickenpox, especially for those at increased risk of contracting the disease e.g. healthcare workers and persons living in institutional settings. […] Varicella vaccination is effective in preventing illness or modifying varicella severity if used within 3 days, and possibly up to 5 days, of exposure.
  • #13 Chickenpox – Infectious Diseases – Merck Manual Professional Edition
    https://www.merckmanuals.com/professional/infectious-diseases/herpesviruses/chickenpox
    Infection provides lifelong protection. […] Potentially susceptible people should take strict precautions to avoid people capable of transmitting the infection. […] A live-attenuated varicella vaccine is available in 2 formulations in the United States: […] All healthy children and susceptible adults should receive 2 doses of live-attenuated varicella vaccine. […] Vaccination is particularly important for women of child-bearing age, those at high risk for exposure, and those who have contact with individuals at higher risk for severe disease. […] Vaccination of health care workers who do not have evidence of varicella immunity is recommended. […] After exposure, chickenpox can be prevented or attenuated by intramuscular (IM) administration of varicella-zoster immune globulin (VariZIG).
  • #14 Patient education: Chickenpox prevention and treatment (Beyond the Basics) – UpToDate
    https://www.uptodate.com/contents/chickenpox-prevention-and-treatment-beyond-the-basics/print
    If you are at risk for chickenpox but are unsure whether you have had the infection, you can have a blood test to check for immunity to varicella. […] To be fully vaccinated, adults and children 13 years and older need two doses of the varicella vaccine, given at least four weeks apart. […] The varicella vaccine contains a live virus, so it is not recommended for people with a compromised immune system or moderate to severe illness. […] The most common side effects of the varicella vaccine are redness or soreness at the injection site and a mild rash (usually about five spots). […] If you or your child has been exposed to someone with chickenpox or shingles, call your healthcare provider immediately and ask what you should do. The varicella vaccine can be given, even after being exposed to the virus. […] Pregnant women who are exposed to the virus cannot receive the varicella vaccine, but they may need to take varicella immune globulin (brand name: VariZIG), an injection that can help to protect against infection.
  • #15 Patient education: Chickenpox prevention and treatment (Beyond the Basics) – UpToDate
    https://www.uptodate.com/contents/chickenpox-prevention-and-treatment-beyond-the-basics
    Chickenpox vaccine precautions — The varicella vaccine contains a live virus, so it is not recommended for people with a compromised immune system or moderate to severe illness. […] Chickenpox vaccine side effects — The most common side effects of the varicella vaccine are redness or soreness at the injection site and a mild rash (usually about five spots). […] If you or your child has been exposed to someone with chickenpox or shingles, call your healthcare provider immediately and ask what you should do. The varicella vaccine can be given, even after being exposed to the virus. […] Pregnant women who are exposed to the virus cannot receive the varicella vaccine, but they may need to take varicella immune globulin (brand name: VariZIG), an injection that can help to protect against infection.
  • #16 Chickenpox – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/chickenpox/symptoms-causes/syc-20351282
    Do not get the chickenpox vaccine if you’re pregnant. If you decide to get vaccinated before pregnancy, don’t try to get pregnant during the series of shots or for one month after the last dose of the vaccine. […] Parents often wonder whether vaccines are safe. Since the chickenpox vaccine became available, studies have found that it’s safe and it works well. Side effects are often mild. They include pain, redness, soreness and swelling at the site of the shot. Rarely, you might get a rash at the site or a fever.
  • #17 Varicella-Zoster Virus Disease: Adult and Adolescent OIs | NIH
    https://clinicalinfo.hiv.gov/en/guidelines/hiv-clinical-guidelines-adult-and-adolescent-opportunistic-infections/varicella-zoster
    Some experts would serologically screen adults with HIV without a history of prior varicella or varicella vaccination for VZV IgG. […] However, the value of this approach may be limited by the lack of sensitivity of commercially available VZV antibody assays (particularly for vaccine-induced antibody). […] No studies have evaluated the vaccine in adolescents or adults with HIV, but many experts recommend varicella vaccination (2 doses, administered 3 months apart) for VZV-susceptible people with HIV aged 18 years with CD4 counts 200 cells/mm3 (BIII). […] If varicella vaccination results in disease caused by vaccine virus (a rare event), therapy with acyclovir is recommended (AIII). […] Administration of varicella vaccine to more severely immunocompromised people with HIV (CD4 counts 200 cells/mm3) is contraindicated (AIII).
  • #18 Varicella-zoster virus post-exposure management and prophylaxis: A review
    https://pmc.ncbi.nlm.nih.gov/articles/PMC6931226/
    Exposure, evidence of immunity, and immune status determine recommended prophylaxis. […] Vaccination may prevent infection or mitigate disease severity in eligible persons. […] Varicella zoster immune globulin is recommended for certain individuals. […] Post-exposure varicella vaccination may prevent infection or mitigate disease severity in persons eligible for vaccination. […] Post-exposure prophylaxis with varicella zoster immune globulin is indicated for populations ineligible for vaccination, including immunocompromised children and adults, pregnant women, newborns of mothers with varicella shortly before or after delivery, and premature infants. […] Post-exposure prophylaxis with varicella vaccination in eligible immunocompetent hosts is recommended to prevent or mitigate infection, limit disease transmission, and help protect against potential future VZV exposure. […] Varicella zoster immune globulin is recommended post-exposure for individuals at high risk for severe varicella disease who lack evidence of immunity to varicella and for whom varicella vaccine is contraindicated.
  • #19
    https://www.gov.uk/government/publications/post-exposure-prophylaxis-for-chickenpox-and-shingles/guidelines-on-post-exposure-prophylaxis-pep-for-varicella-or-shingles-january-2023
    Chickenpox (varicella) infection in immunosuppressed individuals, susceptible pregnant individuals and neonates can result in severe and even life-threatening varicella disease. Post-exposure prophylaxis (PEP) is recommended to attenuate disease and reduce the risk of complications such as pneumonitis, rather than to prevent infection in these at-risk individuals. […] In summary, antivirals are now recommended for post-exposure prophylaxis for all at risk groups including susceptible neonates. In addition, for neonates designated in Group 1 such as those exposed to their mother within one week of delivery (either in utero or post-delivery) the antiviral treatment should be supplemented with intravenous (i.v.) varicella immunoglobulin either as a hyperimmune product (such as Varitect CP) or normal intravenous immunoglobulin (IVIG). A bolus dose of IVIG may also be considered for eligible groups for whom oral antivirals are contraindicated.
  • #20 Managing Varicella (Chickenpox) Exposures in Health Care Settings – MN Dept. of Health
    https://www.health.state.mn.us/diseases/varicella/hcp/hcexposure.html
    Varicella (chickenpox) is spread by direct contact and inhalation of aerosols from vesicles or respiratory secretions. Standard precautions, plus airborne precautions and contact precautions, should be followed until all lesions are crusted over. Patients should be removed from any waiting rooms or public areas and placed in a negative airflow room as soon as varicella is suspected. […] Exposed individuals without evidence of immunity are recommended to receive post-exposure prophylaxis as follows: Healthy individuals age 12 months or older who are not up to date on varicella vaccine should be given varicella vaccine (as long as it is not contraindicated) within 5 days of exposure. […] To prevent transmission of varicella in health care facilities, all health care workers should have evidence of immunity to varicella. This information should be documented and readily available.
  • #21 Varicella (chickenpox) vaccines: Canadian Immunization Guide – Canada.ca
    https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/page-24-varicella-chickenpox-vaccine.html
    Post-exposure immunization may be required depending on the level of exposure to VZV. […] Univalent varicella vaccine is the post-exposure management of choice for susceptible, healthy, non-pregnant persons. For optimal effectiveness, univalent varicella vaccine should be given as soon as possible, preferably within 72 hours, after exposure. […] The decision to administer VarIg should be based on fulfilling all of the following four criteria: The exposed person is susceptible to varicella, There has been a significant exposure to a person with varicella or HZ, The exposed person is at increased risk of severe varicella, Post-exposure immunization with univalent varicella vaccine is contraindicated. […] Post-exposure immunization is useful in preventing or limiting varicella outbreaks in hospitals, child care facilities and homeless shelters. […] Varicella immunization should be a priority for susceptible workers including health care workers, child care workers, and teachers of young children.
  • #22 Chickenpox Treatment & Management: Approach Considerations, Treatment in Healthy Children, Treatment in Immunocompetent Adults
    https://emedicine.medscape.com/article/1131785-treatment
    Varicella-zoster immune globulin (VariZIG) administered intramuscularly (IM) can prevent or attenuate chickenpox following exposure. Eligible candidates include the following: Individuals with leukemia, immunodeficiencies, or other severe debilitating illnesses without immunity; Pregnant individuals without immunity; Neonates whose parent developed chickenpox shortly before or after delivery; Neonates born at less than 28 weeks gestation exposed to a non-maternal source, even if the parent is immune. […] VariZIG should be administered as soon as possible, ideally within 10 days of exposure, to modify or prevent the disease. Exposed, susceptible individuals eligible for vaccination should be vaccinated as soon as possible after exposure. Vaccination can be effective in preventing or mitigating the disease if administered within 3 to 5 days post-exposure. […] To prevent nosocomial transmission, the CDC recommends postexposure prophylaxis with either vaccination or varicella-zoster immunoglobulin, depending on the immune status, for exposed healthcare workers and patients without evidence of immunity.
  • #23 Chickenpox – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/chickenpox/diagnosis-treatment/drc-20351287
    For people who are at high risk of complications from chickenpox, providers sometimes prescribe medicines to shorten the length of the illness and to help lower the risk of complications. […] In some cases, your provider may suggest that you get the chickenpox vaccine after you’ve been exposed to the virus. This can prevent the disease or help make it less severe.
  • #24 Vaccines for post-exposure prophylaxis against varicella (chickenpox) in children and adults | NITAG RESOURCE CENTER
    https://www.nitag-resource.org/resources/vaccines-post-exposure-prophylaxis-against-varicella-chickenpox-children-and-adults
    The prevention of varicella (chickenpox) using live attenuated varicella vaccines has been demonstrated both in randomised controlled trials (RCTs) and in population-based immunisation programmes in countries such as the United States and Australia. […] The use of varicella vaccine in persons who have recently been exposed to the varicella zoster virus has been studied as a form of post-exposure prophylaxis (PEP). […] Overall, 13 out of 56 vaccine recipients (23%) developed varicella compared with 42 out of 54 placebo (or no vaccine) recipients (78%). […] These small trials suggest varicella vaccine administered within three days to children following household contact with a varicella case reduces infection rates and severity of cases.
  • #25 Chickenpox and shingles – including symptoms, treatment and prevention | SA Health
    https://www.sahealth.sa.gov.au/wps/wcm/connect/public+content/sa+health+internet/conditions/infectious+diseases/chickenpox+and+shingles/chickenpox+and+shingles+-+including+symptoms+treatment+and+prevention
    People at high risk of complications from chickenpox infection (for example, people with leukaemia, young babies or pregnant women) should seek medical advice regarding VZIG if they have been exposed to a person with chickenpox or shingles. […] Antiviral medicines may also sometimes be used to prevent chickenpox after exposure. […] Several studies have shown that chickenpox vaccine is effective in preventing chickenpox infection, particularly moderate to severe disease, following exposure. This is generally successful when given within 3 days, and up to 5 days after exposure, with earlier administration preferable. […] A vaccine to prevent shingles is licensed in Australia for use in adults 50 years of age and older who have not previously received a dose of zoster (shingles) vaccine. The vaccine is free for people aged 70 years as part of the National Immunisation Program. From 1 November 2016 the vaccine is also free for a five-year catch up for people aged 71-79 years.
  • #25 Chickenpox and shingles – including symptoms, treatment and prevention | SA Health
    https://www.sahealth.sa.gov.au/wps/wcm/connect/public+content/sa+health+internet/conditions/infectious+diseases/chickenpox+and+shingles/chickenpox+and+shingles+-+including+symptoms+treatment+and+prevention
    Exclude people with chickenpox and shingles from childcare, preschool, school and work until all blisters have dried (usually about 5 days). Some remaining scabs are not a reason for continued exclusion. […] Immunisation against chickenpox is recommended in the National Immunisation Program. In South Australia this is given as the combined measles, mumps, rubella, varicella (MMRV) vaccine. A chickenpox only vaccine is also available for children and adults who did not receive the combined measles, mumps, rubella and varicella vaccine as children. […] Varicella-zoster immunoglobulin (VZIG) is made from blood products and contains antibodies to the varicella-zoster virus. Antibodies are proteins produced by the body as part of the immune response which help the body to fight infections. VZIG is effective in preventing or reducing the severity of chickenpox if given to non-immune people within 96 hours of exposure to a person with chickenpox or shingles.
  • #26 SciELO Brazil – Vaccines for post-exposure prophylaxis against varicella (chickenpox) in children and adults Vaccines for post-exposure prophylaxis against varicella (chickenpox) in children and adults
    https://www.scielo.br/j/spmj/a/GYphMBysbGNjpf7ZtXSsg9S/
    Live attenuated varicella vaccines for the prevention of varicella (chickenpox) has been demonstrated both in randomised controlled trials (RCTs) and in population-based immunisation programmes in countries such as the United States. […] The use of varicella vaccine in persons who have recently been exposed to the varicella zoster virus has been studied as a form of post-exposure prophylaxis (PEP). […] To assess the efficacy and safety of vaccines for use as PEP for the prevention of varicella in children and adults. […] Overall, 13 out of 56 vaccine recipients (18%) developed varicella compared with 42 out of 54 placebo (or no vaccine) recipients (78%). […] In the three studies, most subjects received PEP within three days following exposure; too few subjects were vaccinated four to five days post exposure to ascertain the efficacy of vaccine given more than three days after exposure.
  • #27 Chickenpox (Varicella)
    https://dermnetnz.org/topics/chickenpox
    A person with chickenpox is contagious 12 days before the rash appears and until all the blisters have formed scabs. This may take 5-10 days. Children should stay away from school or childcare facilities throughout this contagious period. Adults with chickenpox who work among children should also remain home. […] As chickenpox may cause complications in immunocompromised individuals and pregnant women, these people should avoid visiting friends or family when there is a known case of chickenpox. In cases of inadvertent contact, see your doctor who may prescribe special preventive treatment. […] Vaccination is available for chickenpox and is highly recommended. […] Chickenpox is highly preventable by vaccination with live attenuated varicella vaccine. The vaccine is subsidised („scheduled”) for infants aged 15 months in New Zealand as well as non-immune individuals who are immunosuppressed or are in other special groups. If in New Zealand, refer to the Immunisation Advisory Centre for up-to-date information.
  • #28
    https://www.gov.uk/government/publications/post-exposure-prophylaxis-for-chickenpox-and-shingles/guidelines-on-post-exposure-prophylaxis-pep-for-varicella-or-shingles-january-2023
    Post-exposure prophylaxis is recommended for individuals who fulfil all of the following 3 criteria: significant exposure to chickenpox (varicella) or shingles (zoster) during the infectious period, at increased risk of severe chickenpox such as immunosuppressed individuals, neonates and susceptible pregnant women, no antibodies to varicella-zoster virus (VZV) urgent VZV antibody testing can be performed within 24 hours. […] Oral aciclovir (or valaciclovir) is now the first choice of PEP for susceptible immunosuppressed individuals, all susceptible pregnant women at any stage of pregnancy and infants at high risk. […] The only exception in starting treatment on day 7 is in Group 1 neonates whose mothers develop chickenpox (but not shingles) in the period 7 days before to 7 days after delivery.
  • #29
    https://www.gov.uk/government/publications/post-exposure-prophylaxis-for-chickenpox-and-shingles/guidelines-on-post-exposure-prophylaxis-pep-for-varicella-or-shingles-january-2023
    Varicella-zoster immunoglobulin for i.v. administration (Varitect CP) is produced by Biotest as a solution for i.v. infusion and is dispensed as 25 IU/ml. It is recommended that a treatment dose of 25 IU/kg to 50 IU/kg (1 to 2 ml/kg) (up to a maximum of 5mls (one vial)) is administered as a single dose as post-exposure prophylaxis for neonates, exposed to intrauterine VZ infection within the last 7 days of pregnancy, with rash onset in the mother presenting within 1 week of delivery. […] Contacts who cannot receive antivirals should be given IVIG at a dose of 0.2g per kg body weight (4 ml/kg for a 5% solution) instead. […] All immunosuppressed individuals as defined in chapter 6 of the Green Book (Immunisation against infectious disease) are at risk of severe chickenpox and should be assessed for the need for prophylaxis following a significant exposure.
  • #30 Chickenpox (varicella)
    https://www.rch.org.au/clinicalguide/guideline_index/Chickenpox_(varicella)/
    Chickenpox is usually a self-limiting disease in immunocompetent children, requiring symptomatic treatment only. […] Treatment with aciclovir is reserved for premature neonates or those 7 days of age, immunocompromised children, and children with systemic or central nervous system disease. […] Varicella Zoster Immune Globulin (VZIG) should be given to an infant whose mother develops chickenpox 7 days before to 2 days after delivery, and to children at risk of complications of chickenpox. […] The National Immunisation Program currently includes a single dose of a varicella-containing vaccine (MMR-V) at 18 months of age. […] The Australian Technical Advisory Group on Immunisation (ATAGI) recommends that adolescents 14 years of age receive 2 doses of varicella vaccine, at least 4 weeks apart.
  • #31 Chickenpox – Infectious Diseases – Merck Manual Professional Edition
    https://www.merckmanuals.com/professional/infectious-diseases/herpesviruses/chickenpox
    The VariZIG immune globulin should be given as soon as possible (and within 10 days of exposure) and may modify or prevent varicella. […] Vaccination should be given as soon as possible to exposed, susceptible healthy patients eligible for vaccination. […] To prevent nosocomial transmission, the CDC recommends postexposure prophylaxis with vaccination or varicella-zoster immunoglobulin, depending on immune status, for exposed health care workers and patients without evidence of immunity.
  • #32 Chickenpox (varicella)
    https://www.rch.org.au/clinicalguide/guideline_index/Chickenpox_(varicella)/
    Children must be excluded from school/kindergarten/childcare until all lesions crusted over. […] VZV infection is a notifiable infection in some States. Contact local health department. […] Pregnant women who have had contact with chickenpox should be reviewed within 24 hours, regardless of the stage of pregnancy. […] VZIG should be administered within 96 hours of exposure but can be effective if administered up to 10 days following exposure.
  • #33 Oral acyclovir prophylaxis of varicella after intimate contact – PubMed
    https://pubmed.ncbi.nlm.nih.gov/9427463/
    Objectives: Whether oral acyclovir (ACV) given in late incubation can prevent clinical varicella or not. […] Conclusions: Oral ACV administration to healthy susceptible subjects at the beginning of secondary viremia in the late incubation period (9 days after exposure) can effectively prevent or modify clinical varicella.
  • #34 Immune Response to Varicella After Acyclovir Prophylaxis | AAFP
    https://www.aafp.org/pubs/afp/issues/2000/0215/p1145a.html
    Primary varicella infection can often be prevented or at least limited by administration of the varicella vaccine within 72 hours of exposure to chickenpox or herpes zoster. […] When timely vaccination is not possible, acyclovir prophylaxis may be an alternative and may be effective even if it is not initiated until seven to 14 days after exposure. […] The authors conclude that cell-mediated immunity to VZV develops following exposure to chickenpox in children who receive acyclovir prophylaxis. […] The authors state that the varicella vaccine is the first choice for prophylaxis, but acyclovir is an alternative if vaccination is not possible within a few days after exposure. […] A VZV immune status should be determined in children who receive acyclovir prophylaxis to document immunity and avoid unnecessary administration of varicella vaccine in children with acquired immunity.
  • #35
    https://www.gov.uk/government/publications/post-exposure-prophylaxis-for-chickenpox-and-shingles/guidelines-on-post-exposure-prophylaxis-pep-for-varicella-or-shingles-january-2023
    The rationale for PEP in pregnant women is two-fold: reduction in severity of maternal disease and theoretical reduction in the risk of fetal infection for women contracting varicella in the first 20 weeks of pregnancy. […] In light of the existing evidence on the safety of aciclovir, the efficacy of aciclovir in preventing clinical chickenpox in healthy and immunosuppressed contacts, equivalence of antivirals as PEP and that VZIG is no longer available, antivirals are now the treatment of choice for exposure to varicella or shingles for susceptible women exposed in any stage of pregnancy. […] Post-exposure prophylaxis is recommended for: Group 1 – Neonates whose mothers develop chickenpox (but not shingles) in the period 7 days before to 7 days after delivery: VZV IgG antibody testing of the neonate or mother is not needed. Varitect (intravenous varicella immunoglobulin) or IVIG should be started as soon as possible and preferably within 7 days of exposure.
  • #36 Varicella-Zoster Virus Disease: Adult and Adolescent OIs | NIH
    https://clinicalinfo.hiv.gov/en/guidelines/hiv-clinical-guidelines-adult-and-adolescent-opportunistic-infections/varicella-zoster
    For people with HIV who are susceptible to VZV, post-exposure prophylaxis following known or suspected VZV exposure is recommended (AII). […] After close contact with a person who has active varicella or herpes zoster, adolescents and adults with HIV who are susceptible to VZV (particularly those with CD4 counts 200 cells/mm3) should receive VariZIG as soon as possible (preferably within 96 hours), but up to 10 days after exposure (AIII). […] Given the cost of obtaining VariZIG, it is reasonable to check VZV serology before administering VariZIG to people who do not have a clinical history of chickenpox or shingles and no documentation of varicella vaccination (AIII). […] The risk of VZV transmission is greater with exposure to varicella than localized herpes zoster. […] Long-term prophylaxis with anti-VZV drugs, such as acyclovir or valacyclovir, to prevent varicella is not recommended (AIII).
  • #37 Varicella-Zoster Virus Disease: Adult and Adolescent OIs | NIH
    https://clinicalinfo.hiv.gov/en/guidelines/hiv-clinical-guidelines-adult-and-adolescent-opportunistic-infections/varicella-zoster
    Long-term administration of anti-VZV drugs to individuals with HIV to prevent episodes of herpes zoster is not routinely recommended (AII). […] However, in a randomized, placebo-controlled study in Africa that evaluated daily acyclovir prophylaxis (acyclovir 400 mg orally [PO] twice a day) administered to people with HIV/HSV-2 coinfection who were not taking ART, acyclovir prophylaxis reduced the rate of herpes zoster by 62%. […] Acyclovir did not prevent recurrent zoster episodes in patients with prior history of herpes zoster. […] People with HIV who are taking suppressive anti-herpes medications (i.e., acyclovir, valacyclovir, or famciclovir) for other indications such as prevention of genital herpes may receive some additional benefit in reduction of risk of herpes zoster, but the relative risk reduction in people who are receiving ART is unknown.
  • #38 Infection Prevention | Varicella Isolation | NewYork-Presbyterian
    https://www.nyp.org/patients-visitors/infection-prevention/varicella-isolation
    Varicella isolation is used to help keep individuals who are not immune to the Chickenpox safe from having contact with patients with the active disease. […] Do not enter the room if you have not had Chickenpox or the vaccine. […] If you have had the Chickenpox or the vaccine, perform hand hygiene before entering the room. […] Perform hand hygiene before leaving the room.
  • #39 Chickenpox | Doctor
    https://patient.info/doctor/chickenpox-pro
    Chickenpox prevention […] The most infectious period is from 24 hours before the rash appears, but infectivity continues until all the lesions are dry and have crusted over (usually about 5 days after the onset of the rash). During this time, a person with chickenpox should avoid contact with: […] People who are immunocompromised. […] Pregnant women. […] Infants aged 4 weeks or less. […] Children with chickenpox should be kept away from school or nursery until all the vesicles have crusted over. […] Varicella vaccines contain live, attenuated virus. […] The two-dose vaccination schedule (doses given 4 to 8 weeks apart) provides about 98% protection in children and about 75% protection in adolescents and adults. […] Pre-exposure vaccination is recommended for: […] Non-immune healthcare workers. […] Individuals who may be exposed to varicella virus in the course of their work, in virology laboratories and clinical infectious disease units. […] Healthy susceptible contacts of immunocompromised patients where continuing close contact is unavoidable.
  • #40 Varicella zoster infection (chickenpox): management in children (1008) | NHSGGC
    https://clinicalguidelines.scot.nhs.uk/ggc-paediatric-guidelines/ggc-paediatric-guidelines/infectious-disease/varicella-zoster-infection-chickenpox-management-in-children-1008/
    To provide guidance on the management of chickenpox and its complications in children under the age of 16, and the use of post exposure prophylaxis in neonates and those at risk of severe infection. This guideline does not cover the treatment of young people who are pregnant, for whom additional advice should be sought from obstetrics. […] The aim of post exposure prophylaxis is to protect individuals who are at high risk of severe chickenpox. Give prophylaxis to any child who is immunocompromised with a low antibody titre to Varicella Zoster Virus, after a significant exposure. […] Prophylaxis is recommended in certain groups of neonates in case of significant exposure see Table 1 below for these scenarios. Most at risk are neonates whose mother develops chickenpox in the week before or after delivery. […] Patients may still get chickenpox following prophylactic treatment and families should be advised on the symptoms and signs of infection and to present immediately should they develop.
  • #41 Pediatric Chickenpox Treatment & Management: Approach Considerations, Supportive Therapy, Antiviral Therapy
    https://emedicine.medscape.com/article/969773-treatment
    Isolate patients with varicella because the disease is highly contagious and airborne spread can occur. Isolation is especially important if the hospital also admits patients who are immunocompromised because their exposure to the disease can be serious and even fatal. […] Varicella zoster immune globulin (VariZIG by Cangene) was approved by the FDA in December 2012. It is indicated for high-risk individuals within 10 days (ideally within 4 days) of chickenpox exposure. This agent reduces complications and the mortality rate of varicella, not its incidence. It is used as postexposure prophylaxis in high-risk individuals; for immunologically normal patients, postexposure prophylaxis using varicella vaccine is preferred. […] Prophylaxis or treatment is required with VZIG and acyclovir. Without these drugs, mortality rates may be as high as 30%.
  • #42 Chickenpox and Effective Prevention Measures
    https://www.ajpmph.com/ajpmph-articles/chickenpox-and-effective-prevention-measures-104407.html
    Chickenpox, also known as varicella, is a highly contagious viral infection caused by the Varicella-Zoster Virus (VZV). […] Fortunately, vaccination has proven to be a highly effective method for preventing chickenpox and its potential complications. […] Vaccination is the most effective way to prevent chickenpox. The varicella vaccine has been widely available and recommended for children since the mid-1990s. It is a safe and reliable method for protecting against the virus and reducing the severity of the illness in those who do contract it after vaccination. […] The vaccine is typically administered in two doses: The first dose between the ages of 12 and 15 months and the second dose between 4 and 6 years old. The vaccine is also recommended for susceptible adolescents and adults who have not had chickenpox or received the vaccine.
  • #43 Chickenpox and Effective Prevention Measures
    https://www.ajpmph.com/ajpmph-articles/chickenpox-and-effective-prevention-measures-104407.html
    Isolation is crucial to prevent the spread of the virus. Infected individuals should stay home until all blisters have crusted over, usually about 5-7 days after the rash first appears. […] Practicing good hygiene is essential in preventing the spread of chickenpox. Regular hand washing with soap and water, covering the mouth and nose when coughing or sneezing, and avoiding close contact with infected individuals can help reduce the risk of transmission. […] Chickenpox is a common childhood illness that can be prevented through vaccination. The varicella vaccine has proven to be safe and effective, reducing the incidence of chickenpox and its complications. In addition to vaccination, practicing good hygiene and isolation measures can help control the spread of the virus.
  • #44 What is Chickenpox: Symptoms, Causes & Prevention Tips | Max Hospital
    https://www.maxhealthcare.in/blogs/chickenpox-symptoms-causes-and-preventions
    Practising good hygiene can help reduce the spread of the varicella-zoster virus. Encourage frequent handwashing with soap and water, especially after coughing, sneezing, or using the bathroom. Avoid touching the face, particularly the eyes, nose, and mouth, to minimise the risk of transferring the virus from contaminated surfaces to mucous membranes. […] For individuals who have been exposed to chickenpox but are not immune to the virus, post-exposure prophylaxis with the varicella vaccine or varicella-zoster immune globulin (VZIG) may be recommended, particularly for those at high risk of complications.
  • #45 Chickenpox Prevention Tips: Protect Your Child This Spring | MrMed
    https://www.mrmed.in/health-library/health-care/chickenpox-prevention-tips?srsltid=AfmBOopA2GFfUdHDkAXXJNEqzIy-jPNS6FAUIFg9xTZTLfG5JPDr0bA-
    2. Avoid contact with infected individuals: If someone in your community has chickenpox, try to limit close contact. Since the virus spreads easily through respiratory droplets, it’s vital to practice social distancing and keep children away from infected individuals as much as possible. […] 3. Boost your immune system: A strong immune system helps your body fight off infections. Ensure you’re eating a balanced diet rich in vitamins (particularly Vitamin C and Vitamin D), exercising regularly, and getting enough sleep to support immune health. […] 4. Practice proper hygiene: Good hygiene is the first line of defence. Wash your hands thoroughly with soap and water, especially after touching public surfaces or coming into contact with anyone who might be infected. Teach children the importance of handwashing, too.
  • #46 Chickenpox Prevention Tips: Protect Your Child This Spring | MrMed
    https://www.mrmed.in/health-library/health-care/chickenpox-prevention-tips?srsltid=AfmBOopA2GFfUdHDkAXXJNEqzIy-jPNS6FAUIFg9xTZTLfG5JPDr0bA-
    5. Disinfect common areas regularly: Surfaces such as doorknobs, light switches, and countertops are prime spots for the chickenpox virus to linger. Use disinfectants regularly to clean high-touch areas and reduce the spread of germs in your home, school, or office. […] 6. Monitor symptoms and stay home when sick: If you or your child starts showing chickenpox symptoms (fever, tiredness, itchy rash), stay home and avoid contact with others to prevent spreading the virus further. This will help stop the chain of transmission before it gets out of hand. […] 7. Encourage healthy lifestyles: Promote a healthy lifestyle by encouraging regular physical activity, stress management, and adequate hydration. A healthy body can better resist infections like chickenpox. […] 8. Educate others about the importance of vaccination: One of the best ways to prevent outbreaks is by educating friends, family, and your community about the importance of vaccination. Ensure that everyone understands how the vaccine works and why it’s essential for preventing both chickenpox and its potential complications.
  • #47 Pediatric Chickenpox Treatment & Management: Approach Considerations, Supportive Therapy, Antiviral Therapy
    https://emedicine.medscape.com/article/969773-treatment
    The AAP recommends excluding affected children from school until the sixth day of rash. However, this may not prevent spread of varicella, because the child is infective before the rash appears. Children with chickenpox should avoid nonimmune pregnant women, unimmunized young infants, and others with immunodeficiencies or who are taking prednisone long term. No other activity restrictions are needed for young children with uncomplicated varicella. […] Postexposure prophylaxis with the vaccine, if provided within 36-72 hours of contact, can prevent or attenuate disease in the exposed individual.
  • #48 Chickenpox and shingles (varicella / herpes zoster)
    https://www.health.vic.gov.au/infectious-diseases/chickenpox-and-shingles-varicella-herpes-zoster
    Chickenpox and shingles can be controlled by vaccination. […] Varicella-containing vaccine is recommended for children aged 12 months to 14 years, adolescents aged 14 years and over, and adults who have not received 2 doses of varicella-containing vaccine. […] A single dose of varicella-containing vaccine is 80-85% effective in preventing chickenpox and very effective against severe disease. […] Vaccination may be used to prevent or attenuate illness if given to susceptible contacts within 5 days (preferably 72 hours) of first exposure. […] ZIG prevents or modifies severity of varicella in people at high risk who report a significant exposure to varicella or herpes zoster. […] Timely vaccination of susceptible contacts is indicated to contain an outbreak. […] Immunisation against chickenpox is provided free of charge to eligible people under the National Immunisation Program Schedule. […] Vaccination with varicella vaccine is contraindicated in immunocompromised people and pregnant women.
  • #49 Chickenpox Prevention Tips: Protect Your Child This Spring | MrMed
    https://www.mrmed.in/health-library/health-care/chickenpox-prevention-tips?srsltid=AfmBOopA2GFfUdHDkAXXJNEqzIy-jPNS6FAUIFg9xTZTLfG5JPDr0bA-
    9. Avoid crowded places: If possible, limit your time in crowded places like amusement parks or busy airports, especially if your child hasn’t yet had chickenpox or the vaccine. While social distancing is not always possible in these settings, being cautious can reduce exposure. […] 10. Watch for early signs of outbreaks in your area: Keep an eye out for reports of chickenpox outbreaks, particularly in schools and daycare centres. If an outbreak is reported in your area, take extra precautions to avoid exposure. This might mean limiting social interactions or staying home from large events. […] To prevent chickenpox in spring, ensure everyone is vaccinated, particularly children and those at risk. Practice good hygiene, avoid close contact with infected individuals, and disinfect commonly touched surfaces regularly.
  • #50 Post Exposure Prophylaxis for Chickenpox Guide – Acibadem Health Point – ACIBADEM Hospitals – Acibadem Health Group
    https://www.acibademhealthpoint.com/post-exposure-prophylaxis-for-chickenpox-guide/
    The objectives of PEP for chickenpox include: Preventing or reducing the severity of chickenpox symptoms. Minimizing the risk of complications associated with chickenpox, such as bacterial infections or pneumonia. Limiting the transmission of the varicella virus to susceptible individuals, including those with weakened immune systems and pregnant women. […] Chickenpox post exposure prophylaxis (PEP) offers several significant benefits in terms of preventing the spread of the virus and minimizing the risk of complications for individuals exposed to chickenpox. […] One of the primary benefits of PEP for chickenpox is its ability to minimize the transmission of the varicella virus. By administering antiviral medication or immunization to individuals exposed to chickenpox, the replication of the virus can be suppressed, reducing the likelihood of infecting others.
  • #51 Varicella-Zoster Virus (Chickenpox and Shingles) & Communicable Diseases | Health & Senior Services
    https://health.mo.gov/living/healthcondiseases/communicable/chickenpox.php
    Yes, make sure all your vaccines are up to date, especially if you are planning a pregnancy. Vaccination is the best way to protect yourself and those you love. If you are not immune, you should be vaccinated. You will receive two doses of varicella (chickenpox) vaccine one month apart. You should avoid becoming pregnant for at least one month after the last vaccination. Varicella vaccine should not be given to pregnant women. If you are pregnant, have your healthcare provider give you the varicella vaccine after your baby is delivered. […] Because of these risks, pregnant women without evidence of immunity to varicella who have been exposed to the virus may be given varicella-zoster immune globulin (VZIG) to reduce their risk of disease complications. […] Newborns whose mothers develop varicella rash from 5 days before to 2 days after delivery are at risk for neonatal varicella, associated with mortality as high as 30%. These infants should receive preventive treatment with varicella-zoster immune globulin (VZIG).
  • #52 Chickenpox (varicella) or shingles (zoster) post-exposure risk assessment: does the person need PEP (post exposure prophylaxis)? – Primary Care Notebook
    https://primarycarenotebook.com/pages/infectious-disease/chickenpox-varicella-or-shingles-zoster-post-exposure-risk-assessment-does-the-person-need-pep-post-exposure-prophylaxis
    Antivirals are now recommended for post-exposure prophylaxis for all at risk groups apart from susceptible neonates exposed within one week of delivery (either in utero or post-delivery). Varicella zoster immunoglobulin (VZIG) is recommended for those for whom oral antivirals are contraindicated (1,2) […] Post exposure prophylaxis is recommended for individuals who fulfil all of the following 3 criteria: significant exposure to chickenpox (varicella) or shingles (zoster) during the infectious period, at increased risk of severe chickenpox such as immunosuppressed individuals, neonates and pregnant women, no antibodies to varicella-zoster virus (VZV) – urgent VZV antibody testing can be performed within 24 hours […] PEP (post exposure prophylaxis) (antivirals or VZIG, if antivirals contraindicated) should be offered if VZV IgG is 100 mIU/ml […] individuals with VZV antibody levels of 150 mIU/ml or greater are unlikely to benefit from VZIG, and therefore individuals with VZV IgG 150 mIU/ml in a quantitative assay, or negative or equivocal in a qualitative assay should be offered PEP.
  • #53 Chickenpox (Varicella Zoster) Antiviral Prescribing
    https://www.hse.ie/eng/services/list/2/gp/antibiotic-prescribing/conditions-and-treatments/skin-soft-tissue/chickenpox/
    Non-immune women significantly exposed to varicella at any stage of pregnancy should be offered post exposure prophylaxis (PEP). […] Consider prescribing oral aciclovir within 24 hours of onset of rash in patients with one or more of the following: […] Pregnant women, who have not had chickenpox, should avoid patients with chickenpox/shingles.
  • #54 Chickenpox Prevention: How To Prevent Chickenpox From Spreading
    https://www.webmd.com/children/vaccines/understanding-chickenpox-prevention
    The American Academy of Pediatrics recommends that children be immunized with the varicella zoster vaccine to prevent chickenpox at 12-15 months and a second dose between ages 4-6 for complete protection. […] The vaccine is also a protection to vulnerable people, such as non-immune women who plan to become pregnant. […] A similar vaccine — but in a higher dose — is also available for the elderly who already had chickenpox to prevent painful outbreaks of shingles.
  • #55 Varicella-Zoster Virus Disease: Adult and Adolescent OIs | NIH
    https://clinicalinfo.hiv.gov/en/guidelines/hiv-clinical-guidelines-adult-and-adolescent-opportunistic-infections/varicella-zoster
    One U.S. Food and Drug Administration (FDA)-approved vaccine is currently available for the prevention of herpes zoster in immunocompetent adults. […] Given that the risk of herpes zoster is high among people with HIV, and the vaccine appears safe, administration of RZV to people with HIV 18 years of age and older is recommended following the FDA-approved schedule for persons without HIV (intramuscular [IM] dose at 0 and 26 months) (AIII).
  • #56 Chickenpox Prevention: How to Avoid the Varicella-Zoster Virus
    https://www.healthline.com/health/chicken-pox-prevention
    Chickenpox is preventable through vaccination. All children, adolescents, and adults who arent immune to chickenpox should be vaccinated to prevent getting the disease. […] In addition to getting vaccinated, you can help prevent the spread of chickenpox through practicing good hygiene and reducing exposure to people who have chickenpox.
  • #57 Post Exposure Prophylaxis for Chickenpox Guide – Acibadem Health Point – ACIBADEM Hospitals – Acibadem Health Group
    https://www.acibademhealthpoint.com/post-exposure-prophylaxis-for-chickenpox-guide/
    Early detection of chickenpox is crucial in effectively managing the condition and implementing prompt post exposure prophylaxis. Recognizing the symptoms of chickenpox early on allows individuals to seek appropriate medical intervention, reducing the risk of complications and preventing the spread of the virus. […] Varicella post exposure prophylaxis involves administering antiviral medications, such as acyclovir, within a specified timeframe after exposure to chickenpox. The goal is to prevent or lessen the severity of the infection. It is essential to adhere to the prescribed treatment plan for optimal results. […] Post exposure prophylaxis (PEP) for chickenpox is an essential step in preventing the spread of the varicella virus and ensuring the well-being of individuals who have been exposed. By understanding the importance of chickenpox prevention and considering appropriate treatment options, individuals can take proactive measures to protect themselves and others from the potentially severe consequences of the disease.
  • #58 How to Prevent Chickenpox: Practical Tips and Advice
    https://www.medicoverhospitals.in/articles/chicken-pox-prevention-tips-keep-children-safe
    Understanding and implementing chickenpox prevention strategies are crucial for reducing the risk of this infectious disease. By following recommended vaccination schedules, practicing good hygiene, and taking necessary precautions, you can effectively prevent chickenpox and protect yourself and your loved ones from its effects. Stay informed and proactive to ensure a healthier and safer environment. […] Yes, a varicella vaccine is available, which is highly effective in preventing chickenpox. It’s recommended that children receive the vaccine as part of their routine immunization schedule. […] The varicella vaccine is typically given to children around one year, with a second dose administered between 4 to 6 years of age. Consult your healthcare provider for the recommended schedule. […] If your child has been exposed to chickenpox, consult your healthcare provider. They may recommend preventive measures or early vaccination to minimize the risk of infection.
  • #59 Chickenpox Prevention Tips: Protect Your Child This Spring | MrMed
    https://www.mrmed.in/health-library/health-care/chickenpox-prevention-tips?srsltid=AfmBOopA2GFfUdHDkAXXJNEqzIy-jPNS6FAUIFg9xTZTLfG5JPDr0bA-
    Spring is a time for renewal, but it’s also a time when chickenpox outbreaks can spread more easily. By taking preventive measures, like ensuring everyone is vaccinated, practising good hygiene, and avoiding exposure to infected individuals, you can significantly reduce the risk of a chickenpox outbreak in your community.
  • #60 Chickenpox: Symptoms, Treatment, and Prevention — Healthy Acadia
    https://healthyacadia.org/blog/chickenpox-symptoms-treatment-and-prevention
    The most effective way to prevent chickenpox is through vaccination. In the United States, the Centers for Disease Control and Prevention (CDC) recommends the Varicella vaccine, administered in two doses for optimal protection. The vaccine is safe and highly effective, with over 90% efficacy in preventing illness. […] It’s important to note that individuals should not receive the chickenpox vaccine if they are pregnant. However, vaccination before pregnancy or during the postpartum period is safe and recommended. Consulting a healthcare provider is essential to determine the appropriateness of vaccination for oneself or one’s child. […] Understanding its symptoms, seeking timely medical attention when necessary, and ensuring vaccination are crucial steps in managing and preventing the spread of this contagious illness.