Materiały źródłowe

• #1 About Haemophilus influenzae Disease | H. influenzae | CDC

  https://www.cdc.gov/hi-disease/about/index.html

  H. influenzae can cause many different types of infections. Symptoms depend on the part of the body that’s infected. Serious infections can result in long-term health problems and death. […] The most common serious infections caused by H. influenzae are: pneumonia (a lung infection), bloodstream infection, meningitis (swelling of the lining of the brain and spinal cord), epiglottitis (swelling of the throat), cellulitis (skin infection), infectious arthritis (swelling of the joint).

• #2

  https://www.who.int/europe/news-room/fact-sheets/item/haemophilus-influenzae-type-b-(hib)

  Haemophilus influenza are bacteria commonly found in the upper respiratory tract, which are transmitted by droplets from people who are infected (but not necessarily symptomatic) to those who are susceptible. The time between infection with Hib and the appearance of symptoms is 2 to 10 days. If these bacteria enter the blood stream, becoming invasive, they can cause pneumonia, meningitis, sepsis, or other serious diseases. […] Although Hib diseases may occur in any age group, over 90% of cases of invasive Hib disease occur in children 5 years of age. Hib meningitis can lead to complications such as blindness, deafness, and learning disabilities and sometimes can lead to death.

• #3 Haemophilus Influenzae Type B (Hib) | Disease Outbreak Control Division

  https://health.hawaii.gov/docd/disease_listing/haemophilus-influenzae-type-b-hib/

  Haemophilus influenzae (H. influenzae) is a type of bacteria that can cause many different kinds of infections. These infections can range from mild ear infections to severe diseases. […] The most common types of invasive disease caused by H. influenzae are: Pneumonia* (lung infection), Bacteremia (blood infection), Meningitis (infection of the covering of the brain and spinal cord), Epiglottitis (swelling of the windpipe that can cause breathing trouble), Cellulitis (skin infection), Infectious arthritis (inflammation of the joint). […] Babies and children younger than 5 years old are most at risk for H. influenzae disease. Most children with invasive disease need care in a hospital. Even with treatment, as many as 1 out of 20 children with Hib meningitis dies and as many as 1 out of 5 children who survive will have brain damage or become deaf.

• #4 Haemophilus influenzae Type B – Epidemiology

  https://www.vdh.virginia.gov/epidemiology/epidemiology-fact-sheets/haemophilus-influenzae-type-b-hib-disease-haemophilus-b/

  Symptoms depend on the part of the body thats infected. Serious infections causing meningitis, pneumonia, and bloodstream infections can result in long-term health problems and death. […] Symptoms generally appear in less than 10 days after exposure and more commonly within 24 days.

• #5 Haemophilus influenzae type b (Hib) Disease Fact Sheet

  https://health.maryland.gov/phpa/pages/haemophilus-influenzae-type-b.aspx

  Haemophilus influenzae type b (Hib) is a bacterium that causes serious infections. […] When disease occurs, it usually is in children 2 months to 5 years of age. Hib can cause meningitis (inflammation of the brain and spinal cord covering) and other infections such as pneumonia (lung infection), ear, skin, joint, and blood infections. […] Symptoms to look for include: Meningitis, Fever, Stiff neck, Drowsiness, Extreme irritability, Sudden vomiting, Other Hib infections, Symptoms at site of infection (for example: skin or joint redness, tenderness, or swollen area). […] The time period between when someone is exposed to Hib and when symptoms develop is unknown, but may be as short as 2 to 4 days.

• #6 Search our Website

  https://www.simcoemuskokahealth.org/topics/InfectiousDiseases/DiseaseInformation/FactSheetsEH/haemophilus-influenzae-type-b-invasive

  Hib disease is caused by the Haemophilus Influenzae b bacteria that can cause serious illness, especially in young children. Hib disease can lead to complications like meningitis (inflammation of the coverings of the brain and spinal cord), bloodstream infections, pneumonia, arthritis and infections of other parts of the body. […] Fever is one symptom that is present in all forms of Hib infections. Other symptoms of Hib infection depend on the part of the body affected. Meningitis is the most common illness of invasive Hib disease, followed by epiglottitis and bloodstream infections. Symptoms of meningitis may include sudden onset of fever, vomiting, lethargy and stiff neck. Epiglottitis is a medical emergency as swelling of the epiglottis can lead to difficulty breathing and can be life-threatening. […] Symptoms generally appear less than 10 days after exposure, usually within two to four days.

• #7

  https://historyofvaccines.org/diseases/hib-haemophilus-influenzae-type-b/

  Haemophilus Influenzae type b, commonly known as Hib, is a bacterium that can cause severe infections, particularly in young children. […] Hib bacteria can cause many types of invasive disease, including meningitis, pneumonia, cellulitis (skin infection), septic arthritis (joint infection) and epiglottitis (infection of the epiglottis, causing obstruction or closing of the windpipe). […] Before the Hib vaccine was introduced, meningitis infection of the membranes that cover the brain was the most common Hib-induced invasive disease. Symptoms include fever, stiff neck, and impaired mental status. Meningitis results in permanent hearing impairment or other neurological conditions in 15-30% of patients who survive it. […] Because the spectrum of Hib disease ranges from meningitis to pneumonia, the types of complications vary depending on the type of Hib infection. Many of these are forms of neurologic damage, including blindness, deafness, and mental retardation. […] For Hib meningitis (the most common form of invasive Hib disease), the case fatality rate is 2-5%.

• #8 Haemophilus influenzae type b (Hib) – Vaccinarsi in Sardegna

  https://www.vaccinarsinsardegna.org/en/science-knowledge/preventable-diseases/haemophilus-influenzae-hib

  Haemophilus influenzae type b (Hib) is a bacterium that often causes severe infections, especially in children under the age of 5. […] Hib usually causes a flu-like illness, which resolves within a few days. However, in some cases, the infection can evolve into severe forms called invasive forms. […] The invasive diseases caused by Hib can affect several organs. The most common types of invasive disease are meningitis, epiglottitis, pneumonia, arthritis, and cellulitis. […] Meningitis is an infection of the membranes that cover the brain and is the most common of the invasive Hib diseases, accounting for 50 – 65% of cases in the pre-vaccination era. The typical symptoms of meningitis are fever, altered mental status and stiffness in the neck. The mortality of Hib meningitis is 2-5% even with appropriate antibiotic therapy. However, those who recover from meningitis can have neurological consequences, which occur in 15 -30% of patients.

• #9 Haemophilus influenzae Disease Symptoms and Complications | H. influenzae | CDC

  https://www.cdc.gov/hi-disease/symptoms/index.html

  Symptoms of H. influenzae disease depend on which part of the body is infected. Generally, the symptoms are similar to other bacterial infections in that part of the body. […] Symptoms of pneumonia (a lung infection) usually include: Fever, chills, or sweating, Cough, Shortness of breath or difficulty breathing, Chest pain, Headache, Muscle pain or aches, Excessive tiredness. […] Symptoms of bloodstream infection usually include: Fever and chills, Excessive tiredness, Pain in the belly, Diarrhea or nausea with or without vomiting, Anxiety, Shortness of breath or difficulty breathing, Altered mental status (confusion). […] Symptoms of meningitis typically include sudden onset of: Fever, Headache, Stiff neck, Nausea with or without vomiting, Photophobia (eyes being more sensitive to light), Altered mental status (confusion).

• #10

  https://www.meningitis.org/meningitis/bacterial-meningitis/haemophilus-influenzae-meningitis

  Haemophilus influenzae meningitis is the swelling of the membranes, called meninges, that cover and protect the brain and spinal cord. It’s caused by the bacteria Haemophilus influenzae. The most virulent strain is Haemophilus influenzae type b (Hib) which causes meningitis in 50-65% of infections. Haemophilus influenzae meningitis occurs when the bacteria invade the body and enter the cerebrospinal fluid (CSF), which surrounds and cushions the brain and spinal cord. In the CSF, bacteria can rapidly multiply and release poisons, causing inflammation and swelling in the meninges. This increases pressure on the brain, producing symptoms of meningitis. […] The symptoms of Haemophilus influenzae meningitis can progress rapidly, and early diagnosis and treatment will increase the chances of a full recovery. Symptoms may include: Fever. Vomiting. Severe headache. Stiff neck (less common in young children). Dislike of bright lights. Seizures (fits). Confused / delirious. Very sleepy / vacant /difficult to wake.

• #11 How Haemophilus Influenzae Type B Affects the Body

  https://www.verywellhealth.com/haemophilus-influenzae-type-b-overview-4589876

  Haemophilus influenzae type b (Hib) is a disease that can cause complications, including meningitis, pneumonia, or a bloodstream infection. Hib is particularly dangerous for young children. Symptoms depend on the area of the body affected, but can include fever, body aches, stiff neck, or difficulty breathing. […] Symptoms of Hib can include: Fever, Lethargy, Vomiting, Stiff neck, Stuffy nose, Sore throat. […] In addition to these symptoms, the Hib bacteria can lead to the development of other serious conditions. In some cases, the bacteria spread to the bloodstream and to other parts of the body. This is called invasive Hib disease. […] The most common mark of invasive Hib disease is bacterial meningitis, or inflammation around the brain and spine. Meningitis from Hib is characterized by the sudden onset of symptoms, including: Fever, Headache, Confusion, irritability, or otherwise altered mental status, Stiff neck, Sensitivity to light, Nausea and/or vomiting, Altered reflexes (in young babies), Irritability (in babies), Poor feeding (in babies), Inactivity (in babies).

• #12 Haemophilus Influenzae Infections | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/haemophilus-influenzae-infections

  Runny nose or cold symptoms that last greater than seven to 10 days […] Complaints of drip in his/her throat from his/her nose […] Headaches […] Facial discomfort […] Bad breath […] Cough […] Fever […] Sore throat […] Swelling around the eye (tends to be worse in the morning) […] For epiglottitis […] Upper respiratory infection, such as a cold […] Quick onset of a very sore throat […] Fever […] Muffled voice […] No cough […] Drooling […] Unable to talk […] Child sits leaning forward […] Child keeps his or her mouth open […] For meningitis in infants […] Irritability […] Sleeping all the time […] Refusing a bottle […] Cries when picked up or being held […] Inconsolable crying […] Bulging fontanelle (or soft spot) […] Behavior changes […] For meningitis in children older than 1 year […] Neck and/or back pain […] Headache […] Nausea and vomiting […] Neck stiffness.

• #13 Haemophilus influenzae Disease Symptoms and Complications | H. influenzae | CDC

  https://www.cdc.gov/hi-disease/symptoms/index.html

  Babies with meningitis may: Be irritable, Vomit, Feed poorly, Appear to be slow or inactive, Have abnormal reflexes. […] Symptoms of ear infections can include: Ear pain, A red, swollen ear drum, Fever, Sleepiness. […] Symptoms of bronchitis can include: Coughing with or without mucus, Soreness in the chest, Excessive tiredness, Mild headache, Mild body aches, Sore throat.

• #14

  https://www.meningitis.org/meningitis/bacterial-meningitis/haemophilus-influenzae-meningitis

  Symptoms in babies and very young children can be slightly different. Their symptoms may include: High temperature (warning: could be normal or low in babies under three months old). Irritability. Vomiting / refusing to feed. A high-pitched cry. A stiff body with jerky movements or else floppy and lifeless. Very sleepy / staring expression / too sleepy to wake up. Tense or bulging soft spot on the top of their head. […] Not everyone with meningitis will get all of these symptoms. People with Haemophilus influenzae meningitis will get worse fast. Check regularly on someone who is unwell and trust your instincts. Get medical help straight away if you or someone you know is seriously ill.

• #15 Haemophilus influenzae type b (Hib) – Vaccinarsi in Sardegna

  https://www.vaccinarsinsardegna.org/en/science-knowledge/preventable-diseases/haemophilus-influenzae-hib

  Haemophilus influenzae type b (Hib) is a bacterium that often causes severe infections, especially in children under the age of 5. […] Hib usually causes a flu-like illness, which resolves within a few days. However, in some cases, the infection can evolve into severe forms called invasive forms. […] The invasive diseases caused by Hib can affect several organs. The most common types of invasive disease are meningitis, epiglottitis, pneumonia, arthritis, and cellulitis. […] Meningitis is an infection of the membranes that cover the brain and is the most common of the invasive Hib diseases, accounting for 50 – 65% of cases in the pre-vaccination era. The typical symptoms of meningitis are fever, altered mental status and stiffness in the neck. The mortality of Hib meningitis is 2-5% even with appropriate antibiotic therapy. However, those who recover from meningitis can have neurological consequences, which occur in 15 -30% of patients.

• #16 Haemophilus Influenzae Type B (Hib) | Disease Outbreak Control Division

  https://health.hawaii.gov/docd/disease_listing/haemophilus-influenzae-type-b-hib/

  Haemophilus influenzae (H. influenzae) is a type of bacteria that can cause many different kinds of infections. These infections can range from mild ear infections to severe diseases. […] The most common types of invasive disease caused by H. influenzae are: Pneumonia* (lung infection), Bacteremia (blood infection), Meningitis (infection of the covering of the brain and spinal cord), Epiglottitis (swelling of the windpipe that can cause breathing trouble), Cellulitis (skin infection), Infectious arthritis (inflammation of the joint). […] Babies and children younger than 5 years old are most at risk for H. influenzae disease. Most children with invasive disease need care in a hospital. Even with treatment, as many as 1 out of 20 children with Hib meningitis dies and as many as 1 out of 5 children who survive will have brain damage or become deaf.

• #17

  https://historyofvaccines.org/diseases/hib-haemophilus-influenzae-type-b/

  Haemophilus Influenzae type b, commonly known as Hib, is a bacterium that can cause severe infections, particularly in young children. […] Hib bacteria can cause many types of invasive disease, including meningitis, pneumonia, cellulitis (skin infection), septic arthritis (joint infection) and epiglottitis (infection of the epiglottis, causing obstruction or closing of the windpipe). […] Before the Hib vaccine was introduced, meningitis infection of the membranes that cover the brain was the most common Hib-induced invasive disease. Symptoms include fever, stiff neck, and impaired mental status. Meningitis results in permanent hearing impairment or other neurological conditions in 15-30% of patients who survive it. […] Because the spectrum of Hib disease ranges from meningitis to pneumonia, the types of complications vary depending on the type of Hib infection. Many of these are forms of neurologic damage, including blindness, deafness, and mental retardation. […] For Hib meningitis (the most common form of invasive Hib disease), the case fatality rate is 2-5%.

• #18 Hib Disease (Haemophilus Influenzae Type b) (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/hib.html

  Hib is short for Haemophilus influenzae type b, a type of bacteria. It can cause serious illnesses, some of which can be life-threatening. […] Symptoms of Hib infection depend on the type of illness it caused. These include: […] Meningitis: This is an infection of the membranes covering the brain and spinal cord. It can cause fever, headache, stiff neck, and vomiting. Very small babies might have seizures, not feed well, or become very cranky or sleepy. This life-threatening disease needs treatment right away. […] Epiglottitis: This severe throat infection can make it hard to swallow or talk. A person might drool and have a very hard time breathing. This too can be life-threatening if not treated right away. […] Pneumonia: This lung infection can cause fever, coughing, and trouble breathing.

• #19 Haemophilus Influenzae Infections in Children | Cedars-Sinai

  https://www.cedars-sinai.org/health-library/diseases-and-conditions—pediatrics/h/haemophilus-influenzae-infections-in-children.html

  A strain of the bacteria that causes more serious disease is called H. influenzae type b (Hib). […] The type b strain caused many cases of infection of the membranes that surround the brain (meningitis). It also caused a life-threatening infection called epiglottitis. […] Symptoms can be a bit different for each child. Below are the most common symptoms. […] Symptoms may include: […] This is an infection of the part of the throat that covers and protects the voice box and windpipe when swallowing. Epiglottitis is a medical emergency. It can be fatal if not treated rapidly. […] Symptoms may include: […] As the infection gets worse, symptoms may include: […] This is an infection of the membranes that surround the brain and spinal cord. Because of the vaccine, meningitis caused by H. influenzae is very rare in children and babies. Symptoms in children older than 1 year may include: […] In babies, symptoms are more general and may include: […] Many of these symptoms may be caused by other health problems. Have your child see their healthcare provider for a diagnosis.

• #20 Haemophilus Influenzae: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/23106-haemophilus-influenzae

  Haemophilus influenzae symptoms in babies and children depend on the specific disease that it causes. […] Symptoms may include: Pain, Loss of appetite, Irritability, Poor sleep, Fever, Drainage, Difficulty hearing. […] Symptoms may include: A frequent, mucus-producing cough, Lack of energy, Wheezing, Fever, Shortness of breath. […] Symptoms may include: Pain, Tenderness, Swelling, Warmth, Discoloration, Blisters, Fever and chills, Fatigue. […] Symptoms may include: Severe sore throat, Fever, Raspy breathing called stridor, Difficulty swallowing, Drooling, Difficulty breathing. […] Symptoms may include: Fever and chills, Cough, Shortness of breath, Difficulty breathing, Sweating, Chest pain, Headache, Muscle pain, Fatigue. […] Symptoms may include: Fever, Headache, Stiff neck, Fatigue, Decreased appetite, Nausea and vomiting, Irritability, Confusion, Seizures. […] Symptoms may include: Fever and chills, Abdominal pain, Nausea and vomiting, Diarrhea, Anxiety or confusion, Fatigue, Shortness of breath, Difficulty breathing. […] Symptoms may include: Fever, Joint pain, Tenderness, Swelling, Warmth, Decreased range of motion.

• #21 How Haemophilus Influenzae Type B Affects the Body

  https://www.verywellhealth.com/haemophilus-influenzae-type-b-overview-4589876

  Symptoms of pneumonia can vary, but they generally include flu-like symptoms. Symptoms may include: Chills, Fever, Sweating, Nasal congestion, Cough, Shortness of breath, Chest pain, Body aches, Fatigue. […] Symptoms of Hib bacteremia mimic symptoms of the flu. Other symptoms may include: Fever, Chills, Fatigue, Abdominal pain, Nausea, Diarrhea, Vomiting, Anxiety, Difficulty breathing, Confusion. […] Symptoms of septic arthritis include: Severe joint pain, Difficulty moving affected joints, Redness or swelling around the affected joint. […] Symptoms of cellulitis include: Red, tender, and/or swollen skin, Blueish tinge to the skin, Skin rash that grows quickly, Fever, Fatigue, Muscle aches, Vomiting or nausea. […] Some symptoms of epiglottitis include: Sore throat that comes on quickly, Fever, Drooling (especially in children), Change in voice (often muffled) or an inability to talk, Trouble breathing.

• #22

  https://www.healthychildren.org/English/health-issues/vaccine-preventable-diseases/Pages/Haemophilus-Influenzae-type-b.aspx

  Epiglottitis is a rare but serious inflammation in the throat, affecting the epiglottis (a flap of tissue at the back of the throat) and occurring most often in children 2 to 4 years of age. Your child’s first symptoms will probably be a severe sore throat and fever (typically a temperature greater than 101F [38.3C]), followed by a raspy or harsh sound called stridor during breathing. As the epiglottis becomes swollen, it can make swallowing difficult, trigger drooling, and may block normal breathing. Some children with epiglottitis have choked to death. Prompt treatment usually can prevent this. […] Other Hib infections. This bacteria causes infection in the joints (arthritis), bones (osteomyelitis), skin of the face (cheek or around the eye), lungs (pneumonia), and even the heart (pericarditis). Signs of infections in these areas include fever, swelling, pain, and redness along with a drastic decrease in energy and activity.

• #23

  https://www.healthychildren.org/English/health-issues/vaccine-preventable-diseases/Pages/Haemophilus-Influenzae-type-b.aspx

  Epiglottitis is a rare but serious inflammation in the throat, affecting the epiglottis (a flap of tissue at the back of the throat) and occurring most often in children 2 to 4 years of age. Your child’s first symptoms will probably be a severe sore throat and fever (typically a temperature greater than 101F [38.3C]), followed by a raspy or harsh sound called stridor during breathing. As the epiglottis becomes swollen, it can make swallowing difficult, trigger drooling, and may block normal breathing. Some children with epiglottitis have choked to death. Prompt treatment usually can prevent this. […] Other Hib infections. This bacteria causes infection in the joints (arthritis), bones (osteomyelitis), skin of the face (cheek or around the eye), lungs (pneumonia), and even the heart (pericarditis). Signs of infections in these areas include fever, swelling, pain, and redness along with a drastic decrease in energy and activity.

• #24 Haemophilus influenzae type b (Hib) | healthdirect

  https://www.healthdirect.gov.au/haemophilus-influenzae-type-b-hib

  Hib can infect your epiglottis, which is a small flap of cartilage at the back of the throat. This can cause your epiglottis to become swollen, and cause epiglottitis. Epiglottitis can cause breathing difficulties, fever, paleness, and difficulty swallowing. […] Hib can cause pneumonia, which is an infection in your lungs. The symptoms of pneumonia include shortness of breath, fever, fatigue (tiredness), loss of appetite, headache, chest pain, and cough. […] Hib infection can also cause osteomyelitis, which is an infection of your bone. This can cause swelling, inflammation, and pain over the bone. […] Hib infection can also cause septic arthritis, which is an infection of the joints. […] Hib can also cause cellulitis, which is an infection of the tissue under the skin. This can cause areas of skin to become red, hot, swollen, and tender. […] Meningitis, epiglottitis and pneumonia caused by Hib infection can cause death. Meningitis and epiglottitis are almost always fatal if left untreated.

• #25 Haemophilus influenzae Disease Symptoms and Complications | H. influenzae | CDC

  https://www.cdc.gov/hi-disease/symptoms/index.html

  Symptoms of H. influenzae disease depend on which part of the body is infected. Generally, the symptoms are similar to other bacterial infections in that part of the body. […] Symptoms of pneumonia (a lung infection) usually include: Fever, chills, or sweating, Cough, Shortness of breath or difficulty breathing, Chest pain, Headache, Muscle pain or aches, Excessive tiredness. […] Symptoms of bloodstream infection usually include: Fever and chills, Excessive tiredness, Pain in the belly, Diarrhea or nausea with or without vomiting, Anxiety, Shortness of breath or difficulty breathing, Altered mental status (confusion). […] Symptoms of meningitis typically include sudden onset of: Fever, Headache, Stiff neck, Nausea with or without vomiting, Photophobia (eyes being more sensitive to light), Altered mental status (confusion).

• #26 Haemophilus Influenzae: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/23106-haemophilus-influenzae

  Haemophilus influenzae symptoms in babies and children depend on the specific disease that it causes. […] Symptoms may include: Pain, Loss of appetite, Irritability, Poor sleep, Fever, Drainage, Difficulty hearing. […] Symptoms may include: A frequent, mucus-producing cough, Lack of energy, Wheezing, Fever, Shortness of breath. […] Symptoms may include: Pain, Tenderness, Swelling, Warmth, Discoloration, Blisters, Fever and chills, Fatigue. […] Symptoms may include: Severe sore throat, Fever, Raspy breathing called stridor, Difficulty swallowing, Drooling, Difficulty breathing. […] Symptoms may include: Fever and chills, Cough, Shortness of breath, Difficulty breathing, Sweating, Chest pain, Headache, Muscle pain, Fatigue. […] Symptoms may include: Fever, Headache, Stiff neck, Fatigue, Decreased appetite, Nausea and vomiting, Irritability, Confusion, Seizures. […] Symptoms may include: Fever and chills, Abdominal pain, Nausea and vomiting, Diarrhea, Anxiety or confusion, Fatigue, Shortness of breath, Difficulty breathing. […] Symptoms may include: Fever, Joint pain, Tenderness, Swelling, Warmth, Decreased range of motion.

• #27 Haemophilus Influenzae Type B (Hib) | Disease Outbreak Control Division

  https://health.hawaii.gov/docd/disease_listing/haemophilus-influenzae-type-b-hib/

  H. influenzae disease causes different symptoms depending on the part of the body it infects. […] Pneumonia (lung infection) symptoms: Fever and chills, Cough, Shortness of breath or difficulty breathing, Sweating, Chest pain, Headache, Muscle pain or aches, Excessive tiredness. […] Bacteremia (blood infection) symptoms: Fever and chills, Excessive tiredness, Pain in the belly, Nausea with or without vomiting, Diarrhea, Anxiety, Shortness of breath or difficulty breathing, Altered mental status (confusion). […] Meningitis (infection of the covering of the brain and spinal cord) symptoms: Fever, Headache, Stiff neck, Nausea with or without vomiting, Increased sensitivity to light (photophobia), Altered mental status (confusion), Limp, loss of alertness (lethargy)/decreased appetite in babies.

• #28 Haemophilus influenzae – Wikipedia

  https://en.wikipedia.org/wiki/Haemophilus_influenzae

  H. influenzaeis responsible for a wide range of localized and invasive infections, typically in infants and children, including pneumonia, meningitis, or bloodstream infections.[8] […] In infants and young children,H. influenzaetype b (Hib) causes bacteremia, pneumonia, epiglottitis and acute bacterial meningitis.[51] On occasion, it causes cellulitis, osteomyelitis, and infectious arthritis. It is one cause of neonatal infection.[52] […] H. influenzaecan cause respiratory tract infections including pneumonia, otitis media, epiglottitis (swelling in the throat), eye infections and bloodstream infection, meningitis. It can also cause cellulitis (skin infection) and infectious arthritis (inflammation of the joint).[49] […] Clinical features of a respiratory tract infection may include initial symptoms of an upper respiratory tract infection mimicking a viral infection, usually associated with low-grade fevers. This may progress to the lower respiratory tract within a few days, with features often resembling those of wheezy bronchitis. Sputum may be difficult to expectorate and is often grey or creamy in color. The cough may persist for weeks without appropriate treatment. Many cases are diagnosed after presenting chest infections that do not respond to penicillins or first-generation cephalosporins. A chest X-ray can identify alveolar consolidation.[36]

• #29 Haemophilus influenzae Infection – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK562176/

  Clinical features depend on the organ infected by H. influenzae, and history and physical examination are geared towards positive and negative findings in the system involved. The most common presentation is pneumonia, which presents as high-grade fever, chills, productive purulent cough, shortness of breath, chest pain, lethargy, and generalized body aches. If the meninges are infected, then symptoms such as fever, headache, altered consciousness, photophobia, nausea, vomiting, and nuchal rigidity are commonly present. Infants usually show nonspecific symptoms such as irritability, drowsiness, poor feeding, and vomiting in addition to the classic symptoms. Epiglottitis presents in unimmunized children, and the affected child appears toxic and adopts a tripod position in an attempt to fully open the airway.

• #30 Haemophilus influenzae Disease Symptoms and Complications | H. influenzae | CDC

  https://www.cdc.gov/hi-disease/symptoms/index.html

  Symptoms of H. influenzae disease depend on which part of the body is infected. Generally, the symptoms are similar to other bacterial infections in that part of the body. […] Symptoms of pneumonia (a lung infection) usually include: Fever, chills, or sweating, Cough, Shortness of breath or difficulty breathing, Chest pain, Headache, Muscle pain or aches, Excessive tiredness. […] Symptoms of bloodstream infection usually include: Fever and chills, Excessive tiredness, Pain in the belly, Diarrhea or nausea with or without vomiting, Anxiety, Shortness of breath or difficulty breathing, Altered mental status (confusion). […] Symptoms of meningitis typically include sudden onset of: Fever, Headache, Stiff neck, Nausea with or without vomiting, Photophobia (eyes being more sensitive to light), Altered mental status (confusion).

• #31 How Haemophilus Influenzae Type B Affects the Body

  https://www.verywellhealth.com/haemophilus-influenzae-type-b-overview-4589876

  Symptoms of pneumonia can vary, but they generally include flu-like symptoms. Symptoms may include: Chills, Fever, Sweating, Nasal congestion, Cough, Shortness of breath, Chest pain, Body aches, Fatigue. […] Symptoms of Hib bacteremia mimic symptoms of the flu. Other symptoms may include: Fever, Chills, Fatigue, Abdominal pain, Nausea, Diarrhea, Vomiting, Anxiety, Difficulty breathing, Confusion. […] Symptoms of septic arthritis include: Severe joint pain, Difficulty moving affected joints, Redness or swelling around the affected joint. […] Symptoms of cellulitis include: Red, tender, and/or swollen skin, Blueish tinge to the skin, Skin rash that grows quickly, Fever, Fatigue, Muscle aches, Vomiting or nausea. […] Some symptoms of epiglottitis include: Sore throat that comes on quickly, Fever, Drooling (especially in children), Change in voice (often muffled) or an inability to talk, Trouble breathing.

• #32 Haemophilus Influenzae Type B (Hib) | Disease Outbreak Control Division

  https://health.hawaii.gov/docd/disease_listing/haemophilus-influenzae-type-b-hib/

  H. influenzae disease causes different symptoms depending on the part of the body it infects. […] Pneumonia (lung infection) symptoms: Fever and chills, Cough, Shortness of breath or difficulty breathing, Sweating, Chest pain, Headache, Muscle pain or aches, Excessive tiredness. […] Bacteremia (blood infection) symptoms: Fever and chills, Excessive tiredness, Pain in the belly, Nausea with or without vomiting, Diarrhea, Anxiety, Shortness of breath or difficulty breathing, Altered mental status (confusion). […] Meningitis (infection of the covering of the brain and spinal cord) symptoms: Fever, Headache, Stiff neck, Nausea with or without vomiting, Increased sensitivity to light (photophobia), Altered mental status (confusion), Limp, loss of alertness (lethargy)/decreased appetite in babies.

• #33 Hib Disease (Haemophilus Influenzae Type b) (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/hib.html

  Sometimes Hib is found only in the bloodstream, where it can travel throughout the body. This is called bacteremia. Children with bacteremia may only have a fever or look very sick. Bacteremia can lead to any of the above illnesses or to sepsis, a dangerous whole-body response to infection. Sepsis can damage many organs or even cause death if not treated right away. […] Hib infection can cause illnesses that are medical emergencies. If your child has trouble breathing or other severe symptoms, call 911 or go to a hospital ER right away.

• #34 Haemophilus Influenzae: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/23106-haemophilus-influenzae

  Haemophilus influenzae symptoms in babies and children depend on the specific disease that it causes. […] Symptoms may include: Pain, Loss of appetite, Irritability, Poor sleep, Fever, Drainage, Difficulty hearing. […] Symptoms may include: A frequent, mucus-producing cough, Lack of energy, Wheezing, Fever, Shortness of breath. […] Symptoms may include: Pain, Tenderness, Swelling, Warmth, Discoloration, Blisters, Fever and chills, Fatigue. […] Symptoms may include: Severe sore throat, Fever, Raspy breathing called stridor, Difficulty swallowing, Drooling, Difficulty breathing. […] Symptoms may include: Fever and chills, Cough, Shortness of breath, Difficulty breathing, Sweating, Chest pain, Headache, Muscle pain, Fatigue. […] Symptoms may include: Fever, Headache, Stiff neck, Fatigue, Decreased appetite, Nausea and vomiting, Irritability, Confusion, Seizures. […] Symptoms may include: Fever and chills, Abdominal pain, Nausea and vomiting, Diarrhea, Anxiety or confusion, Fatigue, Shortness of breath, Difficulty breathing. […] Symptoms may include: Fever, Joint pain, Tenderness, Swelling, Warmth, Decreased range of motion.

• #35 How Haemophilus Influenzae Type B Affects the Body

  https://www.verywellhealth.com/haemophilus-influenzae-type-b-overview-4589876

  Symptoms of pneumonia can vary, but they generally include flu-like symptoms. Symptoms may include: Chills, Fever, Sweating, Nasal congestion, Cough, Shortness of breath, Chest pain, Body aches, Fatigue. […] Symptoms of Hib bacteremia mimic symptoms of the flu. Other symptoms may include: Fever, Chills, Fatigue, Abdominal pain, Nausea, Diarrhea, Vomiting, Anxiety, Difficulty breathing, Confusion. […] Symptoms of septic arthritis include: Severe joint pain, Difficulty moving affected joints, Redness or swelling around the affected joint. […] Symptoms of cellulitis include: Red, tender, and/or swollen skin, Blueish tinge to the skin, Skin rash that grows quickly, Fever, Fatigue, Muscle aches, Vomiting or nausea. […] Some symptoms of epiglottitis include: Sore throat that comes on quickly, Fever, Drooling (especially in children), Change in voice (often muffled) or an inability to talk, Trouble breathing.

• #36 Haemophilus influenzae type b (Hib) | healthdirect

  https://www.healthdirect.gov.au/haemophilus-influenzae-type-b-hib

  Hib can infect your epiglottis, which is a small flap of cartilage at the back of the throat. This can cause your epiglottis to become swollen, and cause epiglottitis. Epiglottitis can cause breathing difficulties, fever, paleness, and difficulty swallowing. […] Hib can cause pneumonia, which is an infection in your lungs. The symptoms of pneumonia include shortness of breath, fever, fatigue (tiredness), loss of appetite, headache, chest pain, and cough. […] Hib infection can also cause osteomyelitis, which is an infection of your bone. This can cause swelling, inflammation, and pain over the bone. […] Hib infection can also cause septic arthritis, which is an infection of the joints. […] Hib can also cause cellulitis, which is an infection of the tissue under the skin. This can cause areas of skin to become red, hot, swollen, and tender. […] Meningitis, epiglottitis and pneumonia caused by Hib infection can cause death. Meningitis and epiglottitis are almost always fatal if left untreated.

• #37

  https://www.health.nsw.gov.au/Infectious/factsheets/Pages/haemophilus_influenzae_b.aspx

  Infection with Hib bacteria can lead to serious illness including meningitis and epiglottitis. With the introduction of Hib vaccine these conditions are now rare. Urgent treatment is necessary as Hib disease can be life threatening. […] Symptoms depend on which part of the body is infected. […] Meningitis – fever, headache, stiff neck, nausea, vomiting and drowsiness […] Epiglottitis – difficulty breathing and swallowing, pale colour and fever […] Pneumonia – shortness of breath, fever, lack of energy, loss of appetite, headache, chest pain and cough. […] Osteomyelitis – swelling, inflammation and pain over the affected bone. […] These conditions can develop quickly, and meningitis and epiglottitis can sometimes be fatal (other germs can also cause these diseases).

• #38 Haemophilus Influenzae: Symptoms and Treatment | Doctor

  https://patient.info/doctor/haemophilus-influenzae

  The most common presentation of invasive Hib disease is meningitis, frequently accompanied by bacteraemia. This presentation accounts for approximately 60% of all cases. […] 15% of cases present with epiglottitis. Epiglottitis most commonly occurs in children aged 2-7 years but can also occur in adults. […] Bacteraemia without any other concomitant infection occurs in 10% of cases. The remainder is made up of cases of septic arthritis, osteomyelitis, cellulitis, pneumonia and pericarditis. […] Hib pneumonia typically occurs in children aged 4 months to 4 years. […] Hib causes septic arthritis and cellulitis in children younger than 2 years. Hib septic arthritis also occurs in adults. […] Presentations include meningitis, pneumonia, respiratory distress, scalp abscess, conjunctivitis and vesicular eruption.

• #39 How Haemophilus Influenzae Type B Affects the Body

  https://www.verywellhealth.com/haemophilus-influenzae-type-b-overview-4589876

  Symptoms of pneumonia can vary, but they generally include flu-like symptoms. Symptoms may include: Chills, Fever, Sweating, Nasal congestion, Cough, Shortness of breath, Chest pain, Body aches, Fatigue. […] Symptoms of Hib bacteremia mimic symptoms of the flu. Other symptoms may include: Fever, Chills, Fatigue, Abdominal pain, Nausea, Diarrhea, Vomiting, Anxiety, Difficulty breathing, Confusion. […] Symptoms of septic arthritis include: Severe joint pain, Difficulty moving affected joints, Redness or swelling around the affected joint. […] Symptoms of cellulitis include: Red, tender, and/or swollen skin, Blueish tinge to the skin, Skin rash that grows quickly, Fever, Fatigue, Muscle aches, Vomiting or nausea. […] Some symptoms of epiglottitis include: Sore throat that comes on quickly, Fever, Drooling (especially in children), Change in voice (often muffled) or an inability to talk, Trouble breathing.

• #40 Haemophilus Influenzae Infections: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/218271-overview

  Signs and symptoms are as follows: […] Hib meningitis: Most serious manifestation of Hib infection; antecedent upper respiratory tract infections are common; Hib meningitis manifestations are indistinguishable from other bacterial meningitis causes […] Cellulitis: Most commonly involves the buccal and periorbital regions; usually associated with fever […] Epiglottitis: Fever, sore throat, dysphagia, drooling, and difficulty breathing […] Hib pneumonia: Clinically indistinguishable from other bacterial pneumonias but usually with insidious onset and a history of fever, cough, and purulent sputum production […] Hib pericarditis: Fever, respiratory distress, and tachycardia […] Septic arthritis: Joint pain, swelling, and decreased mobility […] Occult bacteremia: Fever, anorexia, and lethargy […] Neonatal infections: May have nonspecific manifestations; may include signs/symptoms of bacteremia, sepsis, meningitis, pneumonia, respiratory distress, scalp abscess, conjunctivitis, and vesicular eruption.

• #41 Haemophilus influenzae type b (Hib) – Vaccinarsi in Sardegna

  https://www.vaccinarsinsardegna.org/en/science-knowledge/preventable-diseases/haemophilus-influenzae-hib

  Epiglottitis is an infection of the epiglottis, the structure in the throat that covers and protects the larynx during swallowing. Epiglottitis is dangerous because it can cause airway obstruction with the risk of death from suffocation. […] Other common manifestations of invasive disease are septic arthritis (joint infection), cellulitis (a rapidly progressing skin infection that usually affects the face, head, or neck), and pneumonia.

• #42 Haemophilus influenzae Disease Symptoms and Complications | H. influenzae | CDC

  https://www.cdc.gov/hi-disease/symptoms/index.html

  Babies with meningitis may: Be irritable, Vomit, Feed poorly, Appear to be slow or inactive, Have abnormal reflexes. […] Symptoms of ear infections can include: Ear pain, A red, swollen ear drum, Fever, Sleepiness. […] Symptoms of bronchitis can include: Coughing with or without mucus, Soreness in the chest, Excessive tiredness, Mild headache, Mild body aches, Sore throat.

• #43 How Haemophilus Influenzae Type B Affects the Body

  https://www.verywellhealth.com/haemophilus-influenzae-type-b-overview-4589876

  Symptoms of bronchitis may include: Sore throat, Coughing, Chest soreness, Fatigue, Headache, Body aches. […] Symptoms of the infection may include: Ear pain, A red, swollen eardrum, Fever, Sleepiness (but also trouble sleeping), Grouchiness, Fluid draining from the ears, Loss of balance, Loss of appetite, Pulling or tugging at the ears.

• #44 Content – Health Encyclopedia – University of Rochester Medical Center

  https://www.urmc.rochester.edu/Encyclopedia/content.aspx?ContentTypeID=90&ContentID=P02520

  Symptoms can be a bit different for each child. Below are the most common symptoms. […] Symptoms may include: Abnormal irritability, Trouble sleeping or staying asleep, Tugging or pulling at one or both ears, Fever, Fluid draining from an ear or ears, Loss of balance, Hearing problems, Ear pain, Loss of appetite. […] Symptoms may include: Eye redness, Swelling, Fluid from one or both eyes, Burning feeling of the eyes, Eyes sensitive to light (photophobia). […] Symptoms in younger children may include: Runny nose that lasts longer than 10 to 14 days and nasal fluid may become thick green, yellow, or blood-tinged, Nighttime cough, Occasional daytime cough, Swelling around the eyes. […] Symptoms may include: Suddenly getting a very sore throat, Fever, Muffled voice, No cough, Shortness of breath.

• #45 Haemophilus Influenzae Infections | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/haemophilus-influenzae-infections

  Symptoms vary depending on the specific infection: […] For otitis media (middle ear infection) […] Unusual irritability […] Difficulty sleeping or staying asleep […] Tugging or pulling at one or both ears […] Fever […] Fluid draining from ear(s) […] Loss of balance […] Hearing difficulties […] Ear pain […] Nausea and vomiting […] Diarrhea […] Decreased appetite […] Congestion […] For conjunctivitis […] Redness […] Swelling […] Drainage from one eye or both eyes […] Burning of the eyes […] Sensitivity to light […] For sinusitis in younger children […] Runny nose that lasts greater than seven to 10 days […] Thick green or yellow discharge […] Nighttime cough […] Occasional daytime cough […] Swelling around the eyes […] For sinusitis in older children

• #46 Content – Health Encyclopedia – University of Rochester Medical Center

  https://www.urmc.rochester.edu/Encyclopedia/content.aspx?ContentTypeID=90&ContentID=P02520

  Symptoms can be a bit different for each child. Below are the most common symptoms. […] Symptoms may include: Abnormal irritability, Trouble sleeping or staying asleep, Tugging or pulling at one or both ears, Fever, Fluid draining from an ear or ears, Loss of balance, Hearing problems, Ear pain, Loss of appetite. […] Symptoms may include: Eye redness, Swelling, Fluid from one or both eyes, Burning feeling of the eyes, Eyes sensitive to light (photophobia). […] Symptoms in younger children may include: Runny nose that lasts longer than 10 to 14 days and nasal fluid may become thick green, yellow, or blood-tinged, Nighttime cough, Occasional daytime cough, Swelling around the eyes. […] Symptoms may include: Suddenly getting a very sore throat, Fever, Muffled voice, No cough, Shortness of breath.

• #47 Haemophilus influenzae disease type b (Hib)

  https://info.health.nz/conditions-treatments/infectious-diseases/haemophilus-influenzae-disease-type-b-hib

  Hib can cause a sinus infection. Symptoms include: pain in the face around the sinuses, headache, feeling congested. […] People who are treated and live after Hib meningitis infections can still have long-term complications, including: deafness, brain damage. […] Meningitis and epiglottitis can both cause death. Those who live can have permanent brain or nerve damage.

• #48 Haemophilus influenzae type b (Hib)

  https://www.nhs.uk/conditions/hib/

  Symptoms of Hib infection depend on what part of the body is affected. […] Symptoms may include: a high temperature, difficulty breathing babies may make grunting noises, being sleepier than normal or difficult to wake, blue, grey, pale or blotchy skin, lips or tongue on brown or black skin this may be noticeable under the nails or around the eyes, a rash that looks like small bruises or bleeding under the skin and does not disappear when you press a glass against it, a headache, a sore throat, swollen or painful joints. […] If you or someone you look after has any of these symptoms, call 999 or go to AE. Trust your instincts.

• #49 Haemophilus influenzae type b (Hib)

  https://vaccination-info.europa.eu/en/haemophilus-influenzae-type-b-hib

  Haemophilus influenzae type b (Hib) is a bacterium that can cause an infection with potentially serious and even life-threatening complications. The infection can also cause lifelong impairments such as hearing loss and learning disabilities. It is most common among children under 5 years old with two thirds of cases occurring in children under 12 months. […] What are the symptoms of Hib infection? […] HiB can cause serious complications such as meningitis, sepsis or epiglottitis. […] Fever […] Extreme fatigue, being hard to wake […] Headache […] Sore throat […] Trouble breathing […] Stiff neck […] Vomiting […] Painful or swollen joints […] A rash that does not disappear when pressed […] Pale, blue, grey or blotchy skin, lips or tongue […] Dark skin around the fingernails or eyes.

• #50 Haemophilus influenzae type b (Hib)

  https://www.nhs.uk/conditions/hib/

  Symptoms of Hib infection depend on what part of the body is affected. […] Symptoms may include: a high temperature, difficulty breathing babies may make grunting noises, being sleepier than normal or difficult to wake, blue, grey, pale or blotchy skin, lips or tongue on brown or black skin this may be noticeable under the nails or around the eyes, a rash that looks like small bruises or bleeding under the skin and does not disappear when you press a glass against it, a headache, a sore throat, swollen or painful joints. […] If you or someone you look after has any of these symptoms, call 999 or go to AE. Trust your instincts.

• #51 Hib Disease (Haemophilus Influenzae Type b) (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/hib.html

  Sometimes Hib is found only in the bloodstream, where it can travel throughout the body. This is called bacteremia. Children with bacteremia may only have a fever or look very sick. Bacteremia can lead to any of the above illnesses or to sepsis, a dangerous whole-body response to infection. Sepsis can damage many organs or even cause death if not treated right away. […] Hib infection can cause illnesses that are medical emergencies. If your child has trouble breathing or other severe symptoms, call 911 or go to a hospital ER right away.

• #52 Haemophilus influenzae Infection – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK562176/

  Haemophilus influenzae disease is a name collectively used for any kind of infection caused by the bacteria called Haemophilus influenzae. The most familiar and predominant form is H. influenzae type b (Hib), which infects mostly children and immunocompromised individuals. All of the serotypes, particularly type b, are common etiological agents in lower respiratory tract infections such as pneumonia. They can also cause many other types of serious infections such as meningitis, epiglottitis, cellulitis, septic arthritis, and even empyema and bacteremia. […] The exact incubation period of H.influenzae is still unknown, and it is postulated that it may take as little as few days to cause clinical symptoms. People at increased risk are infants, children younger than 5 years of age, and adults who are 65 or older. There are two types of infections caused by H. influenzae, invasive and non-invasive infections. The invasive Hib infection occurs commonly in children under 5 years of age and mainly includes pneumonia and meningitis. Less commonly, endophthalmitis, urinary tract infections, abscesses, osteomyelitis, and endocarditis can also be the presenting feature of invasive Hib diseases. NTHi is responsible for invasive infections like bacteremia without identifiable focus, bacteremic pneumonia, and meningitis. The majority of non-invasive infections of mucosal surfaces are caused by NTHi in all age groups, such as otitis media in infants and children, sinusitis in children and adults, non-bacteremic pneumonia in the elderly, and acute exacerbation of chronic obstructive pulmonary disease (COPD) in adults and elderly.

• #53

  https://www.who.int/europe/news-room/fact-sheets/item/haemophilus-influenzae-type-b-(hib)

  Haemophilus influenza are bacteria commonly found in the upper respiratory tract, which are transmitted by droplets from people who are infected (but not necessarily symptomatic) to those who are susceptible. The time between infection with Hib and the appearance of symptoms is 2 to 10 days. If these bacteria enter the blood stream, becoming invasive, they can cause pneumonia, meningitis, sepsis, or other serious diseases. […] Although Hib diseases may occur in any age group, over 90% of cases of invasive Hib disease occur in children 5 years of age. Hib meningitis can lead to complications such as blindness, deafness, and learning disabilities and sometimes can lead to death.

• #54 Haemophilus influenzae Infection – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK562176/

  Haemophilus influenzae disease is a name collectively used for any kind of infection caused by the bacteria called Haemophilus influenzae. The most familiar and predominant form is H. influenzae type b (Hib), which infects mostly children and immunocompromised individuals. All of the serotypes, particularly type b, are common etiological agents in lower respiratory tract infections such as pneumonia. They can also cause many other types of serious infections such as meningitis, epiglottitis, cellulitis, septic arthritis, and even empyema and bacteremia. […] The exact incubation period of H.influenzae is still unknown, and it is postulated that it may take as little as few days to cause clinical symptoms. People at increased risk are infants, children younger than 5 years of age, and adults who are 65 or older. There are two types of infections caused by H. influenzae, invasive and non-invasive infections. The invasive Hib infection occurs commonly in children under 5 years of age and mainly includes pneumonia and meningitis. Less commonly, endophthalmitis, urinary tract infections, abscesses, osteomyelitis, and endocarditis can also be the presenting feature of invasive Hib diseases. NTHi is responsible for invasive infections like bacteremia without identifiable focus, bacteremic pneumonia, and meningitis. The majority of non-invasive infections of mucosal surfaces are caused by NTHi in all age groups, such as otitis media in infants and children, sinusitis in children and adults, non-bacteremic pneumonia in the elderly, and acute exacerbation of chronic obstructive pulmonary disease (COPD) in adults and elderly.

• #55 Haemophilus influenzae – Wikipedia

  https://en.wikipedia.org/wiki/Haemophilus_influenzae

  H. influenzaeis responsible for a wide range of localized and invasive infections, typically in infants and children, including pneumonia, meningitis, or bloodstream infections.[8] […] In infants and young children,H. influenzaetype b (Hib) causes bacteremia, pneumonia, epiglottitis and acute bacterial meningitis.[51] On occasion, it causes cellulitis, osteomyelitis, and infectious arthritis. It is one cause of neonatal infection.[52] […] H. influenzaecan cause respiratory tract infections including pneumonia, otitis media, epiglottitis (swelling in the throat), eye infections and bloodstream infection, meningitis. It can also cause cellulitis (skin infection) and infectious arthritis (inflammation of the joint).[49] […] Clinical features of a respiratory tract infection may include initial symptoms of an upper respiratory tract infection mimicking a viral infection, usually associated with low-grade fevers. This may progress to the lower respiratory tract within a few days, with features often resembling those of wheezy bronchitis. Sputum may be difficult to expectorate and is often grey or creamy in color. The cough may persist for weeks without appropriate treatment. Many cases are diagnosed after presenting chest infections that do not respond to penicillins or first-generation cephalosporins. A chest X-ray can identify alveolar consolidation.[36]

• #56 Haemophilus Influenzae Infections | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/haemophilus-influenzae-infections

  Symptoms vary depending on the specific infection: […] For otitis media (middle ear infection) […] Unusual irritability […] Difficulty sleeping or staying asleep […] Tugging or pulling at one or both ears […] Fever […] Fluid draining from ear(s) […] Loss of balance […] Hearing difficulties […] Ear pain […] Nausea and vomiting […] Diarrhea […] Decreased appetite […] Congestion […] For conjunctivitis […] Redness […] Swelling […] Drainage from one eye or both eyes […] Burning of the eyes […] Sensitivity to light […] For sinusitis in younger children […] Runny nose that lasts greater than seven to 10 days […] Thick green or yellow discharge […] Nighttime cough […] Occasional daytime cough […] Swelling around the eyes […] For sinusitis in older children

• #57 How Haemophilus Influenzae Type B Affects the Body

  https://www.verywellhealth.com/haemophilus-influenzae-type-b-overview-4589876

  Symptoms of bronchitis may include: Sore throat, Coughing, Chest soreness, Fatigue, Headache, Body aches. […] Symptoms of the infection may include: Ear pain, A red, swollen eardrum, Fever, Sleepiness (but also trouble sleeping), Grouchiness, Fluid draining from the ears, Loss of balance, Loss of appetite, Pulling or tugging at the ears.

• #58 About Haemophilus influenzae Disease | H. influenzae | CDC

  https://www.cdc.gov/hi-disease/about/index.html

  H. influenzae can cause many different types of infections. Symptoms depend on the part of the body that’s infected. Serious infections can result in long-term health problems and death. […] The most common serious infections caused by H. influenzae are: pneumonia (a lung infection), bloodstream infection, meningitis (swelling of the lining of the brain and spinal cord), epiglottitis (swelling of the throat), cellulitis (skin infection), infectious arthritis (swelling of the joint).

• #59 Haemophilus influenzae disease type b (Hib)

  https://info.health.nz/conditions-treatments/infectious-diseases/haemophilus-influenzae-disease-type-b-hib

  Haemophilus influenzae type b (Hib) is a bacteria that causes serious illness in young tamariki. Hib was once the most common cause of life-threatening bacterial infection in tamariki under 5 years old. It is now less common because of immunisation. […] Symptoms include: stiff neck, fever, headache, eyes being more sensitive to light (photophobia), confusion. […] In the early stages, you usually feel unwell, with fever, headache and vomiting, just like a cold or flu. […] This can cause: blocked airway this can lead to suffocating, noisy breathing, difficulty swallowing, difficulty speaking, fever, drooling. […] Early stages of a lung or chest infection (pneumonia) can be like the flu, with: aches, pains, fever, cough, difficulty breathing. […] Joint infections (septic arthritis) typically cause: extreme discomfort and difficulty using the infected joint, swollen, red and warm joint, fever.

• #60

  https://historyofvaccines.org/diseases/hib-haemophilus-influenzae-type-b/

  Haemophilus Influenzae type b, commonly known as Hib, is a bacterium that can cause severe infections, particularly in young children. […] Hib bacteria can cause many types of invasive disease, including meningitis, pneumonia, cellulitis (skin infection), septic arthritis (joint infection) and epiglottitis (infection of the epiglottis, causing obstruction or closing of the windpipe). […] Before the Hib vaccine was introduced, meningitis infection of the membranes that cover the brain was the most common Hib-induced invasive disease. Symptoms include fever, stiff neck, and impaired mental status. Meningitis results in permanent hearing impairment or other neurological conditions in 15-30% of patients who survive it. […] Because the spectrum of Hib disease ranges from meningitis to pneumonia, the types of complications vary depending on the type of Hib infection. Many of these are forms of neurologic damage, including blindness, deafness, and mental retardation. […] For Hib meningitis (the most common form of invasive Hib disease), the case fatality rate is 2-5%.

• #61 Haemophilus influenzae type b (Hib) | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/infections-and-poisoning/haemophilus-influenzae-type-b-hib/

  Haemophilus influenzae type b (Hib) is a bacterium that can cause a number of serious illnesses, particularly in young children. […] Hib bacteria can cause several serious infections, including: meningitis infection of the lining of the brain and spinal cord, septicaemia blood poisoning, pneumonia infection of the lungs, pericarditis infection of the lining surrounding the heart, epiglottitis infection of the epiglottis, the flap that covers the entrance to your windpipe, septic arthritis infection of the joints, cellulitis infection of the skin and underlying tissues, osteomyelitis infection of the bones. […] Many children who develop Hib infections become very ill and need treatment with antibiotics in hospital. Meningitis is the most severe illness caused by Hib. Even with treatment, 1 in every 20 children with Hib meningitis will die. Those who survive may have long-term problems, such as hearing loss, seizures and learning disabilities.

• #62 Haemophilus Influenzae: Symptoms and Treatment | Doctor

  https://patient.info/doctor/haemophilus-influenzae

  The most common presentation of invasive Hib disease is meningitis, frequently accompanied by bacteraemia. This presentation accounts for approximately 60% of all cases. […] 15% of cases present with epiglottitis. Epiglottitis most commonly occurs in children aged 2-7 years but can also occur in adults. […] Bacteraemia without any other concomitant infection occurs in 10% of cases. The remainder is made up of cases of septic arthritis, osteomyelitis, cellulitis, pneumonia and pericarditis. […] Hib pneumonia typically occurs in children aged 4 months to 4 years. […] Hib causes septic arthritis and cellulitis in children younger than 2 years. Hib septic arthritis also occurs in adults. […] Presentations include meningitis, pneumonia, respiratory distress, scalp abscess, conjunctivitis and vesicular eruption.

• #63 Haemophilus influenzae: Symptoms | survival time | transmission |

  https://prevent-and-protect.com/pathogen/haemophilus-influenzae/

  Typical illnesses caused by the pathogen are pneumonia, sinusitis or bronchitis. […] Particularly in unvaccinated infants, the bacterium can also trigger meningitis, which manifests itself through symptoms such as vomiting, high fever, cramps and a clouding of consciousness. […] Severe consequential damages (such as speech impairment, hearing loss or mental retardation) are possible. […] In addition, inflammation of the epiglottitis may occur within a few hours. […] The mortality rate is especially high for patients with meningitis, with up to 80 percent of patients dying if untreated. […] Even with treatment, the mortality rate is between 5-10 percent. […] Infections with Hib-bacterium are more likely to cause serious infections.

• #64 Haemophilus Influenzae: Symptoms and Treatment | Doctor

  https://patient.info/doctor/haemophilus-influenzae

  The most common presentation of invasive Hib disease is meningitis, frequently accompanied by bacteraemia. This presentation accounts for approximately 60% of all cases. […] 15% of cases present with epiglottitis. Epiglottitis most commonly occurs in children aged 2-7 years but can also occur in adults. […] Bacteraemia without any other concomitant infection occurs in 10% of cases. The remainder is made up of cases of septic arthritis, osteomyelitis, cellulitis, pneumonia and pericarditis. […] Hib pneumonia typically occurs in children aged 4 months to 4 years. […] Hib causes septic arthritis and cellulitis in children younger than 2 years. Hib septic arthritis also occurs in adults. […] Presentations include meningitis, pneumonia, respiratory distress, scalp abscess, conjunctivitis and vesicular eruption.

• #65 Hib Disease (Haemophilus Influenzae Type b) (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/hib.html

  Sometimes Hib is found only in the bloodstream, where it can travel throughout the body. This is called bacteremia. Children with bacteremia may only have a fever or look very sick. Bacteremia can lead to any of the above illnesses or to sepsis, a dangerous whole-body response to infection. Sepsis can damage many organs or even cause death if not treated right away. […] Hib infection can cause illnesses that are medical emergencies. If your child has trouble breathing or other severe symptoms, call 911 or go to a hospital ER right away.

• #66 Haemophilus influenzae Infection – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK562176/

  Clinical features depend on the organ infected by H. influenzae, and history and physical examination are geared towards positive and negative findings in the system involved. The most common presentation is pneumonia, which presents as high-grade fever, chills, productive purulent cough, shortness of breath, chest pain, lethargy, and generalized body aches. If the meninges are infected, then symptoms such as fever, headache, altered consciousness, photophobia, nausea, vomiting, and nuchal rigidity are commonly present. Infants usually show nonspecific symptoms such as irritability, drowsiness, poor feeding, and vomiting in addition to the classic symptoms. Epiglottitis presents in unimmunized children, and the affected child appears toxic and adopts a tripod position in an attempt to fully open the airway.

• #67 Haemophilus influenzae type B (Hib) | Mass.gov

  https://www.mass.gov/info-details/haemophilus-influenzae-type-b-hib

  Hib is most likely spread through droplets, by coughing and sneezing. Your child can get Hib disease by being around other children or adults who may have the bacteria in their throats and not know it. The germs are spread from person to person. If the germs stay in the nose and throat, children probably won’t get sick. But sometimes the germs spread into a child’s lungs or bloodstream and then Hib can cause serious disease. […] Currently, Hib disease occurs primarily in infants who are not fully immunized and almost half of all Hib cases occur in children under 6 months of age. Children and adults with sickle cell anemia, no spleen, weakened immune systems or who are on drugs or treatments that weaken the immune system, also are at higher risk for Hib. […] Protect your children by having them vaccinated. All infants should get a series of four Hib shots starting when they are 2 months old. The rest of the shots are given at 4 months, 6 months and 15 months. There are different schedules for babies between 7 and 15 months old who missed the shots when they were younger. Children 15 months through 4 years of age need at least 1 dose. Children 5 years of age and older and adults with the special health problems described above also need at least 1 dose.

• #68 Haemophilus influenzae type b (Hib)

  https://vaccination-info.europa.eu/en/haemophilus-influenzae-type-b-hib

  Haemophilus influenzae type b (Hib) is a bacterium that can cause an infection with potentially serious and even life-threatening complications. The infection can also cause lifelong impairments such as hearing loss and learning disabilities. It is most common among children under 5 years old with two thirds of cases occurring in children under 12 months. […] What are the symptoms of Hib infection? […] HiB can cause serious complications such as meningitis, sepsis or epiglottitis. […] Fever […] Extreme fatigue, being hard to wake […] Headache […] Sore throat […] Trouble breathing […] Stiff neck […] Vomiting […] Painful or swollen joints […] A rash that does not disappear when pressed […] Pale, blue, grey or blotchy skin, lips or tongue […] Dark skin around the fingernails or eyes.

• #69 Haemophilus influenzae type B (Hib) | Mass.gov

  https://www.mass.gov/info-details/haemophilus-influenzae-type-b-hib

  Hib is most likely spread through droplets, by coughing and sneezing. Your child can get Hib disease by being around other children or adults who may have the bacteria in their throats and not know it. The germs are spread from person to person. If the germs stay in the nose and throat, children probably won’t get sick. But sometimes the germs spread into a child’s lungs or bloodstream and then Hib can cause serious disease. […] Currently, Hib disease occurs primarily in infants who are not fully immunized and almost half of all Hib cases occur in children under 6 months of age. Children and adults with sickle cell anemia, no spleen, weakened immune systems or who are on drugs or treatments that weaken the immune system, also are at higher risk for Hib. […] Protect your children by having them vaccinated. All infants should get a series of four Hib shots starting when they are 2 months old. The rest of the shots are given at 4 months, 6 months and 15 months. There are different schedules for babies between 7 and 15 months old who missed the shots when they were younger. Children 15 months through 4 years of age need at least 1 dose. Children 5 years of age and older and adults with the special health problems described above also need at least 1 dose.

• #70 Haemophilus influenzae disease type b (Hib)

  https://info.health.nz/conditions-treatments/infectious-diseases/haemophilus-influenzae-disease-type-b-hib

  Hib can cause a sinus infection. Symptoms include: pain in the face around the sinuses, headache, feeling congested. […] People who are treated and live after Hib meningitis infections can still have long-term complications, including: deafness, brain damage. […] Meningitis and epiglottitis can both cause death. Those who live can have permanent brain or nerve damage.

• #71 Haemophilus influenzae type b (Hib) | NHS inform

  https://www.nhsinform.scot/illnesses-and-conditions/infections-and-poisoning/haemophilus-influenzae-type-b-hib/

  Haemophilus influenzae type b (Hib) is a bacterium that can cause a number of serious illnesses, particularly in young children. […] Hib bacteria can cause several serious infections, including: meningitis infection of the lining of the brain and spinal cord, septicaemia blood poisoning, pneumonia infection of the lungs, pericarditis infection of the lining surrounding the heart, epiglottitis infection of the epiglottis, the flap that covers the entrance to your windpipe, septic arthritis infection of the joints, cellulitis infection of the skin and underlying tissues, osteomyelitis infection of the bones. […] Many children who develop Hib infections become very ill and need treatment with antibiotics in hospital. Meningitis is the most severe illness caused by Hib. Even with treatment, 1 in every 20 children with Hib meningitis will die. Those who survive may have long-term problems, such as hearing loss, seizures and learning disabilities.

• #72

  http://www.bccdc.ca/health-info/diseases-conditions/haemophilus-influenzae-type-b-hib

  Haemophilus influenzae type b (Hib) is a severe bacterial infection which occurs mostly in infants and children under 5. […] The infection usually starts suddenly with: fever, vomiting, lack of energy, confusion, headache, stiff neck. […] Hib can cause serious and life-threatening infections including meningitis (an infection of the lining that covers the brain) and septicemia (an infection of the blood). Hib bacteria can also cause a serious and life-threatening infection in the throat called epiglottitis. The epiglottis is the tissue in the throat that covers and protects the larynx (windpipe) during swallowing. A child with this infection may have life-threatening difficulty breathing and may need an emergency operation so he doesn’t suffocate or choke to death. […] For every 20 children who get sick, one will die. Permanent complications of infection include brain damage. The brain damage may mean the child will develop an intellectual disability or become deaf or paralyzed.

• #73 Haemophilus influenzae type b (Hib) | healthdirect

  https://www.healthdirect.gov.au/haemophilus-influenzae-type-b-hib

  Hib can infect your epiglottis, which is a small flap of cartilage at the back of the throat. This can cause your epiglottis to become swollen, and cause epiglottitis. Epiglottitis can cause breathing difficulties, fever, paleness, and difficulty swallowing. […] Hib can cause pneumonia, which is an infection in your lungs. The symptoms of pneumonia include shortness of breath, fever, fatigue (tiredness), loss of appetite, headache, chest pain, and cough. […] Hib infection can also cause osteomyelitis, which is an infection of your bone. This can cause swelling, inflammation, and pain over the bone. […] Hib infection can also cause septic arthritis, which is an infection of the joints. […] Hib can also cause cellulitis, which is an infection of the tissue under the skin. This can cause areas of skin to become red, hot, swollen, and tender. […] Meningitis, epiglottitis and pneumonia caused by Hib infection can cause death. Meningitis and epiglottitis are almost always fatal if left untreated.

• #74

  https://www.healthychildren.org/English/health-issues/vaccine-preventable-diseases/Pages/Haemophilus-Influenzae-type-b.aspx

  Epiglottitis is a rare but serious inflammation in the throat, affecting the epiglottis (a flap of tissue at the back of the throat) and occurring most often in children 2 to 4 years of age. Your child’s first symptoms will probably be a severe sore throat and fever (typically a temperature greater than 101F [38.3C]), followed by a raspy or harsh sound called stridor during breathing. As the epiglottis becomes swollen, it can make swallowing difficult, trigger drooling, and may block normal breathing. Some children with epiglottitis have choked to death. Prompt treatment usually can prevent this. […] Other Hib infections. This bacteria causes infection in the joints (arthritis), bones (osteomyelitis), skin of the face (cheek or around the eye), lungs (pneumonia), and even the heart (pericarditis). Signs of infections in these areas include fever, swelling, pain, and redness along with a drastic decrease in energy and activity.

• #75 Haemophilus influenzae type b (Hib)

  https://vaccination-info.europa.eu/en/haemophilus-influenzae-type-b-hib

  Hib infections can be serious and cause life-threatening complications. Complications vary depending on the location of the infection in the body but are usually related to swelling and tissue damage. Complications can include: […] Meningitis (inflammation of the membrane that surrounds the brain and spinal cord) […] Sepsis (serious blood infection/poisoning) […] Epiglottitis (inflammation of the epiglottis, the flap that prevents food from entering the windpipe) […] Pneumonia (infection and inflammation of the lungs) […] Septic arthritis (infection and inflammation of the joints) […] Purulent pericarditis (a life-threatening infection of the sac that surrounds the heart) […] Endocarditis (inflammation of the inner membrane of the heart).

• #76 Haemophilus influenzae: Symptoms | survival time | transmission |

  https://prevent-and-protect.com/pathogen/haemophilus-influenzae/

  Typical illnesses caused by the pathogen are pneumonia, sinusitis or bronchitis. […] Particularly in unvaccinated infants, the bacterium can also trigger meningitis, which manifests itself through symptoms such as vomiting, high fever, cramps and a clouding of consciousness. […] Severe consequential damages (such as speech impairment, hearing loss or mental retardation) are possible. […] In addition, inflammation of the epiglottitis may occur within a few hours. […] The mortality rate is especially high for patients with meningitis, with up to 80 percent of patients dying if untreated. […] Even with treatment, the mortality rate is between 5-10 percent. […] Infections with Hib-bacterium are more likely to cause serious infections.

• #77 Haemophilus influenzae | Healthify

  https://healthify.nz/health-a-z/h/haemophilus-influenzae

  The symptoms of Hib disease are not the same for everyone. The symptoms vary, depending on where the infection is. A baby or young child may only have fever and be irritable. […] Meningitis and epiglottitis can develop quickly and can rapidly cause death if left untreated. You need to see a doctor immediately for treatment. […] About 1 in 20 people with meningitis die and 1 in 3 survivors has permanent brain or nerve damage. About 1 in 100 people with epiglottitis die.

• #78

  https://www.meningitis.org/meningitis/bacterial-meningitis/haemophilus-influenzae-meningitis

  Haemophilus influenzae meningitis is the swelling of the membranes, called meninges, that cover and protect the brain and spinal cord. It’s caused by the bacteria Haemophilus influenzae. The most virulent strain is Haemophilus influenzae type b (Hib) which causes meningitis in 50-65% of infections. Haemophilus influenzae meningitis occurs when the bacteria invade the body and enter the cerebrospinal fluid (CSF), which surrounds and cushions the brain and spinal cord. In the CSF, bacteria can rapidly multiply and release poisons, causing inflammation and swelling in the meninges. This increases pressure on the brain, producing symptoms of meningitis. […] The symptoms of Haemophilus influenzae meningitis can progress rapidly, and early diagnosis and treatment will increase the chances of a full recovery. Symptoms may include: Fever. Vomiting. Severe headache. Stiff neck (less common in young children). Dislike of bright lights. Seizures (fits). Confused / delirious. Very sleepy / vacant /difficult to wake.

• #79 Haemophilus influenzae type b (Hib)

  https://www.nhs.uk/conditions/hib/

  Symptoms of Hib infection depend on what part of the body is affected. […] Symptoms may include: a high temperature, difficulty breathing babies may make grunting noises, being sleepier than normal or difficult to wake, blue, grey, pale or blotchy skin, lips or tongue on brown or black skin this may be noticeable under the nails or around the eyes, a rash that looks like small bruises or bleeding under the skin and does not disappear when you press a glass against it, a headache, a sore throat, swollen or painful joints. […] If you or someone you look after has any of these symptoms, call 999 or go to AE. Trust your instincts.

• #80 Haemophilus influenzae type b – Immunisation Advisory Centre

  https://www.immune.org.nz/diseases/haemophilus-influenzae-type-b

  Hib disease is caused by the bacterium Haemophilus influenzae type b. Infants and children less than five years of age are most vulnerable to Hib infections. […] Hib, for example may present as epiglottitis (severe swelling in the throat) or pneumonia. Symptoms of meningitis include fever, loss of appetite, vomiting, drowsiness, headache, sensitivity to bright light, and neck stiffness. Signs may be vague and non-specific in young infants; they may have a bulging fontanelle. Symptoms of epiglottitis include fever, breathing difficulty, noisy breathing, difficulty swallowing, and drooling. A child with epiglottitis may sit with an extended neck and their tongue sticking out to help them breathe. […] Children with signs of meningitis or epiglottitis should see a doctor very urgently. Hib infection is treated with antibiotics. Supportive therapy may be required which could involve hospitalisation and intensive care.

• #81 Haemophilus influenzae type B (Hib) | Mass.gov

  https://www.mass.gov/info-details/haemophilus-influenzae-type-b-hib

  Haemophilus influenzae type B (called “Hib”) is a serious disease caused by bacteria. It usually affects young children under the age of 5 years. Hib meningitis can cause permanent brain damage and can cause swelling in the airway and lead to suffocation. Hib can also infect the lungs, blood, joints, bones and the thin membrane that covers the heart. Before Hib vaccine, Hib disease was the leading cause of bacterial meningitis among children. […] Hib can also cause less serious illnesses, like bronchitis, sinus infections, and ear infections. The germ can also be carried in the nose and throats of people who feel fine and have no symptoms. […] Yes. Before Hib vaccine, each year about 20,000 children in the United States under 5 years old got severe Hib disease and nearly 1,000 of them died. Since 1988 when Hib vaccine was introduced, Hib disease in infants and young children has decreased by 99% to fewer than 1 case per 100, 000 children younger than 5 years of age.

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