Denga
Objawy

Denga jest wirusową chorobą przenoszoną przez komary Aedes aegypti i Aedes albopictus, wywoływaną przez cztery serotypy wirusa DENV (1-4). Inkubacja trwa 3-14 dni (zwykle 4-7 dni), po czym następuje faza gorączkowa trwająca 2-7 dni, charakteryzująca się wysoką gorączką (39-40°C), bólem głowy (zwłaszcza zaoczodołowym), bólami mięśniowo-stawowymi, nudnościami, wymiotami, wysypką oraz niewielkimi objawami krwotocznymi. W badaniach laboratoryjnych obserwuje się leukopenię, trombocytopenię (<100 x 10⁹/L) oraz podwyższone transaminazy. Faza krytyczna (24-48 godzin) rozpoczyna się po spadku gorączki i wiąże się z ryzykiem ciężkiej dengi, objawiającej się wyciekiem osocza, hemokoncentracją (wzrost hematokrytu ≥20%), hipoproteinemią, zaburzeniami hemodynamicznymi i krwawieniami. Faza zdrowienia trwa 2-3 dni i cechuje się stopniową normalizacją parametrów oraz ustępowaniem objawów, choć zmęczenie może utrzymywać się tygodniami.

Charakterystyka Dengi

Denga (gorączka denga) to choroba wirusowa przenoszona przez komary z rodzaju Aedes, głównie Aedes aegypti i Aedes albopictus. Jest wywoływana przez wirusy dengi, których wyróżniamy cztery serotypy (DENV 1-4). Choroba ta występuje głównie w rejonach tropikalnych i subtropikalnych, stanowiąc istotny problem zdrowia publicznego na świecie.12

Denga jest czasami nazywana „gorączką łamanych kości” (breakbone fever) ze względu na intensywny ból mięśni, kości i stawów, który towarzyszy infekcji i może dawać wrażenie łamania kości, chociaż w rzeczywistości nie powoduje złamań.12

Przebieg choroby

Denga ma charakterystyczny przebieg z wyraźnymi fazami i zróżnicowaną manifestacją kliniczną, od przypadków bezobjawowych po ciężkie, zagrażające życiu postacie.12

Okres inkubacji

Po ukąszeniu przez zakażonego komara, wirus przechodzi okres inkubacji trwający zazwyczaj 3-14 dni, najczęściej 4-7 dni. W tym czasie pacjent pozostaje bezobjawowy.123

Fazy kliniczne dengi

Choroba przebiega w trzech wyraźnych fazach:12

1. Faza gorączkowa

Faza gorączkowa charakteryzuje się:123

2. Faza krytyczna

Faza krytyczna rozpoczyna się w momencie spadku gorączki (deferwescencji), zazwyczaj po 3-7 dniach od początku choroby i trwa zwykle 24-48 godzin. Jest to najbardziej niebezpieczny okres, w którym może dojść do rozwoju ciężkiej dengi.123

Charakterystyczne cechy fazy krytycznej to:12

W tej fazie mogą pojawić się objawy ostrzegawcze ciężkiej dengi:123

  • Silny ból brzucha12
  • Uporczywe wymioty (co najmniej 3 razy w ciągu 24 godzin)1
  • Kliniczne objawy gromadzenia się płynów1
  • Krwawienia z błon śluzowych (dziąseł, nosa)12
  • Powiększenie wątroby12
  • Letarg, niepokój lub drażliwość12
  • Narastająca hemokoncentracja1
3. Faza zdrowienia

W fazie zdrowienia dochodzi do:123

  • Stopniowej reabsorpcji płynów pozanaczyniowych1
  • Ogólnej poprawy stanu klinicznego1
  • Powrotu apetytu1
  • Stabilizacji parametrów hemodynamicznych1
  • Wycofywania się wysypki, która może ulegać złuszczaniu i być swędząca12
  • Normalizacji diurezy1

Ta faza zwykle trwa 2-3 dni. Po przejściu przez fazę zdrowienia, większość pacjentów z łagodną formą dengi wraca do zdrowia w ciągu 1-2 tygodni, chociaż zmęczenie i uczucie osłabienia może utrzymywać się przez dłuższy czas.12

Objawy kliniczne

Objawy dengi mogą być bardzo zróżnicowane – od całkowitego braku objawów klinicznych do ciężkich, zagrażających życiu postaci choroby.12

Denga bezobjawowa

Szacuje się, że około 75% zakażeń wirusem dengi przebiega bezobjawowo lub skąpoobjawowo, co oznacza, że osoby zakażone mogą nie zgłaszać się po pomoc medyczną.123

Łagodna denga

Typowe objawy łagodnej dengi to:123

  • Nagła wysoka gorączka (do 40-41°C)12
  • Silny ból głowy, zwłaszcza zaoczodołowy12
  • Ból mięśni, kości i stawów (tzw. „gorączka łamanych kości”)12
  • Wysypka (różne typy)12
  • Nudności i wymioty12
  • Obrzęk węzłów chłonnych1
  • Ból brzucha1
  • Utrata apetytu1

Charakterystyczny przebieg łagodnej dengi obejmuje wysoką gorączkę przez 2-7 dni, po której może nastąpić jej spadek i ponowny wzrost (przebieg dwufazowy), często określany jako przebieg „siodełkowaty”.12

Wysypka w dengi występuje w charakterystycznym wzorcu:123

  • Początkowe zaczerwienienie lub płaskie, różowe plamy, szczególnie na twarzy, pojawiające się 2-5 dni po wystąpieniu gorączki12
  • Następnie, po spadku gorączki, może pojawić się druga wysypka o charakterze plamisto-grudkowym, rozprzestrzeniająca się z tułowia na kończyny i twarz12

Ciężka denga

Ciężka denga (dawniej określana jako gorączka krwotoczna denga [dengue hemorrhagic fever – DHF] lub zespół wstrząsu pogorączkowego denga [dengue shock syndrome – DSS]) jest najpoważniejszą manifestacją kliniczną zakażenia wirusem dengi. Szacuje się, że około 1 na 20 osób (5%) z objawową dengą rozwinie ciężką postać choroby.123

Ciężka denga definiowana jest jako denga z jednym z następujących objawów klinicznych:12

  • Ciężki wyciek osocza prowadzący do wstrząsu lub gromadzenia płynu z niewydolnością oddechową12
  • Ciężkie krwawienie12
  • Ciężkie uszkodzenie narządów, takie jak zapalenie wątroby (podwyższone transaminazy >1000 IU/L), zaburzenia świadomości lub uszkodzenie serca1

Objawy ostrzegawcze ciężkiej dengi zwykle pojawiają się 24-48 godzin po spadku gorączki i obejmują:123

  • Silny ból brzucha lub tkliwość12
  • Uporczywe wymioty (co najmniej 3 razy w ciągu 24 godzin)12
  • Krwawienie z dziąseł lub nosa12
  • Krew w moczu, stolcu lub wymiocinach12
  • Krwawienie pod skórą (wybroczyny, wylewy)12
  • Trudności w oddychaniu lub przyspieszony oddech12
  • Zmęczenie, niepokój lub drażliwość12
  • Bladość i zimna skóra1
  • Wstrząs (zagrażający życiu stan, w którym ciśnienie krwi jest niskie, a narządy i tkanki nie otrzymują wystarczającej ilości krwi i tlenu)1

Ciężka denga jest stanem zagrażającym życiu i wymaga natychmiastowej opieki medycznej. Nieleczona może prowadzić do zgonu w 10-20% przypadków, jednak przy odpowiednim leczeniu wspomagającym śmiertelność można obniżyć do około 1%.12

Nietypowe manifestacje dengi

Denga może czasami manifestować się nietypowymi objawami, określanymi jako „rozszerzony zespół dengi”, obejmującymi zajęcie różnych narządów:12

Objawy dengi u dzieci

Denga u dzieci może prezentować się inaczej niż u dorosłych:123

  • U niemowląt i małych dzieci objawy są zwykle łagodniejsze1
  • Drgawki gorączkowe mogą występować u dzieci poniżej 6 roku życia1
  • Dzieci mogą mieć więcej nietypowych objawów, takich jak ból gardła1
  • Ciężka denga (DHF/DSS) jest częstsza u dzieci poniżej 15 roku życia1

U niemowląt należy zwracać szczególną uwagę na oznaki odwodnienia, takie jak rzadsze oddawanie moczu, suchość w jamie ustnej, języku lub wargach, brak lub niewielka ilość łez podczas płaczu oraz zapadnięte miękkie miejsca na głowie lub zapadnięte oczy.1

Czynniki ryzyka ciężkiej dengi

Ryzyko rozwinięcia ciężkiej dengi jest wyższe u:123

  • Osób, które przeszły wcześniej zakażenie innym serotypem wirusa dengi (wtórne zakażenie)123
  • Niemowląt i dzieci12
  • Osób starszych (powyżej 65 roku życia)12
  • Kobiet w ciąży12
  • Kobiet (ciężka denga częściej występuje u płci żeńskiej)1

Zmiany laboratoryjne

Typowe zmiany w badaniach laboratoryjnych w przebiegu dengi obejmują:123

  • Trombocytopenię (spadek liczby płytek krwi poniżej 100 x 10⁹/L)12
  • Leukopenię (zmniejszona liczba białych krwinek)12
  • Podwyższony poziom enzymów wątrobowych (transaminaz)1
  • Hemokoncentrację (wzrost hematokrytu o ≥20% w stosunku do wartości wyjściowej)12

Liczba płytek krwi osiąga najniższy poziom około 7-10 dnia choroby, po czym stopniowo wraca do normy.12

Czas trwania i rokowanie

Czas trwania objawów

Typowe trwanie poszczególnych faz dengi:123

  • Objawy zwykle rozpoczynają się 3-14 dni (najczęściej 4-7 dni) po ukąszeniu przez zakażonego komara12
  • Faza gorączkowa trwa 2-7 dni12
  • Faza krytyczna trwa 24-48 godzin12
  • Faza zdrowienia trwa 2-3 dni12

Większość pacjentów z łagodną dengą wraca do zdrowia w ciągu 1-2 tygodni, chociaż niektórzy mogą doświadczać przedłużonego zmęczenia, osłabienia i depresji przez kilka tygodni po ustąpieniu gorączki.123

Rokowanie

Rokowanie w dengi zależy od kilku czynników:123

  • Większość przypadków łagodnej dengi kończy się pełnym wyzdrowieniem bez długotrwałych następstw12
  • Ciężka denga nieleczona może mieć śmiertelność rzędu 10-20%1
  • Przy odpowiednim leczeniu wspomagającym śmiertelność w ciężkiej dengi można zmniejszyć do około 1%12
  • Pacjenci z ciężką dengą, którzy otrzymają natychmiastowe leczenie w szpitalu, mają ponad 99% szans na wyzdrowienie1

Powikłania dengi

Potencjalne powikłania dengi, szczególnie w jej ciężkiej postaci, obejmują:12

  • Uszkodzenie wątroby12
  • Kardiomiopatia1
  • Zapalenie płuc1
  • Zapalenie jąder lub jajników1
  • Drgawki1
  • Encefalopatia1
  • Zapalenie mózgu1
  • Przedłużone zmęczenie i depresja12

Objawy wymagające pilnej interwencji

Następujące objawy wymagają natychmiastowej pomocy medycznej, ponieważ mogą wskazywać na rozwój ciężkiej dengi:123

  • Silny ból brzucha lub tkliwość12
  • Uporczywe wymioty (co najmniej 3 razy w ciągu 24 godzin)12
  • Krwawienie z dziąseł lub nosa12
  • Krew w moczu, stolcu lub wymiocinach12
  • Szybki lub trudny oddech12
  • Bladość i zimna skóra12
  • Skrajne zmęczenie, niepokój lub drażliwość12
  • Trudności z oddawaniem moczu (zmniejszone wydalanie moczu)1
  • Senność lub zaburzenia świadomości1
  • Słabe, ale szybkie tętno1

Różnice w objawach dengi i innych chorób

Diagnoza dengi może być trudna, ponieważ jej objawy mogą być łatwo mylone z objawami innych chorób, takich jak:12

  • Chikungunya1
  • Wirus Zika1
  • Malaria1
  • Dur brzuszny1
  • Grypa i inne infekcje wirusowe12
  • COVID-19 (we wczesnych stadiach może mieć podobne objawy)1

Elementy wyróżniające dengę to:123

  • Charakterystyczny ból za oczami12
  • Intensywny ból mięśni i stawów („gorączka łamanych kości”)12
  • Typowy przebieg gorączki (wysoka gorączka przez kilka dni, następnie spadek i ponowny wzrost)1
  • Charakterystyczna wysypka (początkowo na tułowiu, następnie rozprzestrzeniająca się na kończyny)12
  • Leukopenia i trombocytopenia12

Zalecenia dla pacjentów

Dla pacjentów z podejrzeniem dengi zaleca się:123

  • Skontaktowanie się z lekarzem w celu wykonania badania krwi i postawienia diagnozy12
  • Odpoczynek12
  • Przyjmowanie dużej ilości płynów w celu zapobiegania odwodnieniu12
  • Stosowanie paracetamolu do kontroli gorączki i bólu12
  • Unikanie kwasu acetylosalicylowego (aspiryny) i niesteroidowych leków przeciwzapalnych (np. ibuprofenu), ponieważ mogą zwiększać ryzyko krwawienia12
  • Natychmiastowe zgłoszenie się po pomoc medyczną w przypadku wystąpienia objawów ostrzegawczych ciężkiej dengi123

Podsumowanie objawów i progresji dengi

Faza Czas trwania Główne objawy Zmiany laboratoryjne
Okres inkubacji 3-14 dni (najczęściej 4-7 dni) Brak objawów Brak istotnych zmian
Faza gorączkowa 2-7 dni – Wysoka gorączka (39-40°C)
– Silny ból głowy, zwłaszcza za oczami
– Ból mięśniowy, stawowy i kostny
– Nudności, wymioty
– Wysypka (pojawia się po 2-5 dniach)
– Powiększenie węzłów chłonnych
– Niewielkie krwawienia (wybroczyny, krwawienie z nosa, dziąseł)
– Leukopenia
– Spadek liczby płytek krwi
– Podwyższone transaminazy
Faza krytyczna 24-48 godzin – Spadek gorączki
– Silny ból brzucha
– Uporczywe wymioty
– Krwawienia z błon śluzowych
– Letarg lub niepokój
– Powiększenie wątroby
– Gromadzenie płynów (wodobrzusze, płyn w opłucnej)
– Zaburzenia hemodynamiczne (spadek ciśnienia)
– Pogłębienie trombocytopenii
– Hemokoncentracja (↑ hematokrytu)
– Hipoproteinemia
– Wydłużony czas krzepnięcia
Faza zdrowienia 2-3 dni – Ustępowanie objawów
– Poprawa apetytu
– Stabilizacja parametrów hemodynamicznych
– Wysypka (może się złuszczać i swędzieć)
– Zmęczenie (może utrzymywać się przez kilka tygodni)
– Stopniowa normalizacja liczby płytek
– Normalizacja hematokrytu
– Normalizacja leukocytów (często z leukozytozą)

Kolejne rozdziały

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Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.

  1. 10.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    Dengue fever is the leading cause of arthropod-borne viral disease worldwide, posing a significant global health concern. This disease is also known by various monikers, such as breakbone or 7-day fever, and is characterized by intense muscle spasms, joint pain, and high fever, reflecting both the severity and the duration of symptoms. […] Although most dengue fever cases are asymptomatic, severe illness and mortality can occur. […] The typical incubation period for the disease is 4 to 7 days, with symptoms lasting from 3 to 10 days. Symptoms appearing more than 2 weeks after exposure are unlikely to be attributed to dengue fever. […] The presentation of dengue fever, whether asymptomatic, typical, or severe, is influenced by a complex interplay of host and viral factors. Severe dengue fever, characterized by heightened microvascular permeability and shock syndrome, is often associated with infection by a second dengue virus serotype and the patient’s immune response.
  • #1 Dengue Fever (for Parents) | Nemours KidsHealth
    https://kidshealth.org/en/parents/dengue.html
    Dengue fever can cause fever, headaches, rashes, and pain throughout the body. Although it can be very painful, it’s usually not fatal. Most people who get it start feeling better after several days and recover fully in a couple of weeks. […] Dengue fever used to be called „breakbone fever” because of the severe bone and muscle pain it sometimes causes. While the fever does not break any bones, it can sometimes feel like it does. […] A person with dengue fever may notice: a high fever, pain behind the eyes, pain in the joints, muscles, and/or bones, a severe headache, a rash over most of the body, easy bruising. […] Some people can get a more serious form of the infection called dengue hemorrhagic fever. They’ll have the regular symptoms of dengue fever for a few days. After the fever goes down, they also might have these problems: nausea and vomiting, severe belly pain, trouble breathing, bleeding from the nose or gums, vomiting blood, or blood in their stool (poop).
  • #1 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    Dengue begins abruptly after a typical incubation period of 57 days, and the course follows 3 phases: febrile, critical, and recovery. […] Early clinical findings are nonspecific. Dengue requires a high index of suspicion because recognizing early signs of shock and promptly initiating intensive supportive therapy with intravenous fluids can reduce risk of death among patients with severe dengue to 0.5%. […] Fever typically lasts 27 days and can be biphasic. Other signs and symptoms may include severe headache, retro-orbital pain, myalgia and arthralgia, macular or maculopapular rash; and minor hemorrhagic manifestations including petechia, ecchymosis, purpura, epistaxis, gingival bleeding, hematuria, or a positive tourniquet test result. […] Warning signs of progression to severe dengue usually occur in the late febrile phase around the time of defervescence, and include persistent vomiting, severe abdominal pain, fluid accumulation, mucosal bleeding, lethargy/restlessness, postural hypotension, liver enlargement, and progressive increase in hematocrit (i.e., hemoconcentration).
  • #1
    https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue
    Most people who get dengue will not have symptoms. But for those who do, the most common symptoms are high fever, headache, body aches, nausea, and rash. Most will get better in 12 weeks. Some people develop severe dengue and need care in a hospital. […] In severe cases, dengue can be fatal. […] Most people with dengue have mild or no symptoms and will get better in 12 weeks. Rarely, dengue can be severe and lead to death. […] If symptoms occur, they usually begin 4-10 days after infection and last for 2-7 days. Symptoms may include: high fever (40C/104F), severe headache, pain behind the eyes, muscle and joint pains, nausea, vomiting, swollen glands, rash. […] Individuals who are infected for the second time are at greater risk of severe dengue. […] Severe dengue symptoms often come after the fever has gone away: severe abdominal pain, persistent vomiting, rapid breathing, bleeding gums or nose, fatigue, restlessness, blood in vomit or stool, being very thirsty, pale and cold skin, feeling weak. […] People with these severe symptoms should get care right away. […] After recovery, people who have had dengue may feel tired for several weeks.
  • #1 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    The 3 phases of dengue fever include febrile, critical, and recovery stages. […] During the febrile phase, individuals typically experience a sudden onset of high-grade fever, reaching approximately 40 C, which usually lasts for 2 to 7 days. […] During the critical phase, defervescence marks a period when the temperature typically decreases to approximately 37.5 to 38 C or lower, occurring between days 3 and 7. […] The recovery phase involves the gradual reabsorption of extravascular fluid over 2 to 3 days. […] Expanded dengue virus syndrome refers to unusual or atypical manifestations seen in patients with involvement of various organs such as neurological, hepatic, and renal. […] Common laboratory findings include thrombocytopenia, leukopenia, and elevated levels of aspartate aminotransferase.
  • #1
    https://www.who.int/news-room/questions-and-answers/item/dengue-and-severe-dengue
    Dengue causes flu-like symptoms and lasts for 2-7 days. Dengue fever usually occurs after an incubation period of 4-10 days after the bite of the infected mosquito. […] High Fever (40 C/104 F) is usually accompanied by at least two of the following symptoms: headaches, pain behind eyes, nausea, vomiting, swollen glands, joint, bone or muscle pains, rash. […] Individuals infected for the second time are at greater risk of severe dengue. When developing into severe dengue, the critical phase takes place around 3-7 days after the first sign of illness. Temperature will decrease; this does not mean the person is necessarily recovering. On the other hand, special attention needs to be given to these warning signs as it could lead to severe dengue: severe abdominal pain, persistent vomiting, bleeding gums, rapid breathing, fatigue/restlessness, blood in vomit or stool, being very thirsty, pale and cold skin.
  • #1 Dengue Fever > Fact Sheets > Yale Medicine
    https://www.yalemedicine.org/conditions/dengue-fever
    Symptoms include fever, headache, pain behind the eyes, joint and muscle aches, nausea, vomiting, rash, swollen lymph nodes. […] Most people who become infected do not develop symptoms or instead have mild symptoms, such as fever, headache, pain behind the eyes, nausea, vomiting, and/or rash. Dengue is sometimes called breakbone fever because, in addition to fever, it can cause severe aches and pains, especially in the legs, joints, and back (dengue does not actually cause bones to break). […] However, if symptoms do occur, they typically include: Fever (usually begins four to seven days after getting bitten by an infected mosquito), Pain behind the eyes, Muscle, joint, or bone pain, Nausea and vomiting, Swollen lymph nodes, Rash (two to five days after a fever begins, a flat, red rash may develop; three to six days after a fever begins, a second rash of raised bumps may appear).
  • #1 Symptoms of Dengue and Testing | Dengue | CDC
    https://www.cdc.gov/dengue/signs-symptoms/index.html
    The most common symptom of dengue is fever with any of the following: Aches and pains (eye pain, typically behind the eyes, muscle, joint, or bone pain), Nausea, vomiting, Rash, Any warning sign. […] Symptoms of dengue typically last 27 days. […] Most people will recover after about a week. […] Symptoms of dengue can become severe within a few hours. Severe dengue is a medical emergency. […] About 1 in 20 people who get sick with dengue will develop severe dengue. Severe dengue can result in shock, internal bleeding, and death. […] Watch for warning of severe dengue. Warning signs usually begin in the 24-48 hours after fever has gone away.
  • #1 Dengue fever – UF Health
    https://ufhealth.org/conditions-and-treatments/dengue-fever
    Dengue fever begins with a sudden high fever, often as high as 105F (40.5C), 4 to 7 days after the infection. […] A flat, red rash may appear over most of the body 2 to 5 days after the fever starts. A second rash, which looks like the measles, appears later in the disease. Infected people may have increased skin sensitivity and are very uncomfortable. […] Symptoms of severe dengue can occur 24 to 48 hours after fever has gone away. Severe symptoms include: Severe stomach pain and tenderness, Vomiting often (at least 3 times in 24 hours), Bleeding from the nose or gums, Vomiting blood or passing blood in the stools or urine, Bleeding under the skin (looks like bruises), Difficulty breathing, rapid breathing, Feeling tired, restless, or irritable. […] Mild cases of dengue generally last a week or more. Although uncomfortable, mild dengue fever is not deadly. People with the condition should fully recover. In some Latin American and Asian countries, severe dengue is a leading cause of death and severe illness. Early detection and treatment of severe dengue can greatly reduce the risk of death.
  • #1 Dengue – Infectious Diseases – Merck Manual Professional Edition
    https://www.merckmanuals.com/professional/infectious-diseases/arboviruses-arenaviridae-and-filoviridae/dengue
    Dengue fever usually results in abrupt onset of high fever, headache, myalgias, arthralgias, and generalized lymphadenopathy, followed by a rash that appears with a recurrent fever after an afebrile period. […] After an incubation period of 3 to 15 days, fever, chills, headache, retro-orbital pain with eye movement, lumbar backache, and severe prostration begin abruptly. Extreme aching in the legs and joints occurs during the first hours, accounting for the traditional name of breakbone fever. The temperature rises rapidly to up to 40 C, with relative bradycardia. Bulbar and palpebral conjunctival injection and a transient flushing or pale pink macular rash (particularly of the face) may occur. Cervical, epitrochlear, and inguinal lymph nodes are often enlarged. […] Fever and other symptoms persist 48 to 96 hours, followed by rapid defervescence with profuse sweating. Patients then feel well for about 24 hours, after which fever may occur again (saddleback pattern), typically with a lower peak temperature than the first. Simultaneously, a blanching maculopapular rash spreads from the trunk to the extremities and face.
  • #1 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    The critical phase of dengue begins at defervescence and typically lasts 2448 hours. Most patients clinically improve during this phase, but those with substantial plasma leakage can, within a few hours, develop severe dengue. […] Patients with severe plasma leakage may have pleural effusions, ascites, hypoproteinemia, or hemoconcentration. […] Patients may appear to be well despite early signs of shock. However, once hypotension develops, systolic blood pressure rapidly declines, and irreversible shock and death may ensue despite resuscitation. […] Patients can also develop severe hemorrhagic manifestations, including hematemesis, hematochezia, or menorrhagia, especially if they have been in prolonged shock. […] As plasma leakage subsides, the patient enters the recovery phase and begins to reabsorb extravasated intravenous fluids and pleural and abdominal effusions.
  • #1 Warning signs that your dengue infection is getting worse | gov.sg
    https://www.gov.sg/explainers/warning-signs-that-your-dengue-infection-is-getting-worse
    Feeling nauseous or feverish? Or have a headache that aches from behind the eyes? […] Common symptoms of dengue fever are: Fever, Headache with pain behind the eyes, Muscle and joint aches, Rash, Nausea and vomiting. […] Dengue typically starts off with high fever, accompanied by body aches and pain. The fever typically lasts for 3-5 days. […] The second phase is known as the critical period, and it is the most crucial one to look out for. Your body temperature is coming down (below 38 degrees C), lasting for 48 hours. During this period, your body experiences fluid shifting out of circulation compartments to other body compartments. Fluid may then accumulate in the lungs or abdominal space. Your heart rate, blood pressure may fluctuate, and in severe cases, drop to very low levels that damage your vital organs, such as your kidney and liver.
  • #1 Dengue fever – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/dengue-fever/symptoms-causes/syc-20353078
    Dengue fever causes a high fever 104 F (40 C) and any of the following signs and symptoms: […] When symptoms do occur, they may be mistaken for other illnesses such as the flu and usually begin four to 10 days after you are bitten by an infected mosquito. […] Most people recover within a week or so. In some cases, symptoms worsen and can become life-threatening. This is called severe dengue, dengue hemorrhagic fever or dengue shock syndrome. […] Severe dengue happens when your blood vessels become damaged and leaky. And the number of clot-forming cells (platelets) in your bloodstream drops. This can lead to shock, internal bleeding, organ failure and even death. […] Warning signs of severe dengue fever which is a life-threatening emergency can develop quickly. The warning signs usually begin the first day or two after your fever goes away, and may include: Severe stomach pain, Persistent vomiting, Bleeding from your gums or nose, Blood in your urine, stools or vomit, Bleeding under the skin, which might look like bruising, Difficult or rapid breathing, Fatigue, Irritability or restlessness.
  • #1 VI Department of Health Encourages Public to Know the Symptoms of Dengue – VI Department of Health
    https://doh.vi.gov/vi-department-of-health-encourages-public-to-know-the-symptoms-of-dengue/
    Individuals experiencing dengue symptoms should contact their primary care doctor and get tested for the virus with a blood test, said Commissioner Encarnacion. Rest as much as possible and take acetaminophen. Do not take aspirin or ibuprofen. […] About one (1) in 20 people who get sick with dengue will develop severe dengue, according to the CDC (Center for Disease Control). Infants, pregnant women, and individuals who had dengue in the past are more likely to develop severe dengue. […] Severe dengue usually occurs 24 to 48 hours after a fever has passed. Symptoms include belly pain, tenderness, vomiting (at least 3 times in 24 hours), bleeding from the nose or gums, vomiting blood, or blood in the stool, feeling tired, restless, or irritable. […] If you are experiencing the symptoms of severe dengue, go to the Emergency Room or see your healthcare provider immediately, Commissioner Encarnacion said.
  • #1 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    The recovery-phase rash may desquamate and be pruritic. […] Dengue warning signs include abdominal pain or tenderness, persistent vomiting, clinical fluid accumulation, mucosal bleeding, lethargy, restlessness, and liver enlargement. Patients with warning signs should be monitored closely as they can be more likely to progress to severe disease. […] Severe dengue is defined by dengue with any of the following clinical manifestations: severe plasma leakage leading to shock or fluid accumulation with respiratory distress; severe bleeding; or severe organ impairment such as hepatitis (elevated transaminases 1,000 IU/L), impaired consciousness, or heart impairment.
  • #1 Understanding Dengue Fever | Saint Luke’s Health System
    https://www.saintlukeskc.org/health-library/understanding-dengue-fever
    Mild dengue infection may have few symptoms. Moderate to severe dengue has 3 phases: febrile, critical, and recovery. […] Symptoms of the febrile phase last 3 to 7 days and include: Sudden high fever, Skin redness or red patches on the skin, Severe headache, Pain behind the eyes, Severe joint and muscle pain, Upset stomach (nausea), Vomiting, Easy bruising and bleeding. […] The critical phase often lasts 2 to 3 days. During this time, body temperature may return to normal. Symptoms of the critical phase include: Vomiting that wont stop, Severe pain in the belly (abdomen), Fluid in the chest and belly, Fast breathing, Low blood pressure, Bleeding. […] A person with severe dengue may have trouble breathing, severe bleeding, damage to organs, or dengue shock syndrome. This can be fatal, and is a medical emergency. […] During the recovery phase, there is overall improvement. There may also be a rash and itchy skin. There may be heart and lung problems.
  • #1 How Many Days Does Dengue Fever Last?
    https://redcliffelabs.com/myhealth/fever/how-many-days-does-dengue-fever-last/
    Critical phase of dengue fever: It is the second stage of dengue fever that occurs around 3-7 days after the febrile phase. Some symptoms may include: Bleeding gums or nose, Pale and cold skin, Persistent vomiting, Rapid breathing, Being very thirsty, Severe abdominal pain, Fatigue, Restlessness, Weakness, Heavy menstruation and bleeding for a prolonged time. […] Recovery Stage: This is the final stage of dengue fever, in which the body gradually recovers. The signs of the recovery or final phase include: Overall improvement, The body temperature returns to normal, Normal blood pressure and pulse rate, Improved appetite, It begins to produce a lot of urine, An enlarged liver begins to shrink within 1-2 weeks. […] According to the World Health Organization (WHO), dengue can be classified into dengue without and with symptoms, including vomiting, abdominal pain, difficulty breathing, lethargy, and fluid imbalances. Consult your healthcare provider if you have dengue fever and the symptoms last 3 to 7 days.
  • #1 Persistent Symptoms of Dengue: Estimates of the Incremental Disease and Economic Burden in Mexico
    https://pmc.ncbi.nlm.nih.gov/articles/PMC4856607/
    Fatigue, which results in decreased capacity to work, is common during the acute stage of dengue and may persist for several weeks after recovery. […] If persistent symptoms affect a non-negligible share of the population, previous studies have likely underestimated the burden of dengue. […] Persistent symptoms were usually associated with female gender and older age. […] Despite the uncertainty in our estimates, our results suggest that persistent symptoms of dengue illness may represent a substantial economic and disease burden that has not been elucidated previously.
  • #1 Dengue
    https://www.nhs.uk/conditions/dengue/
    Dengue does not always cause symptoms. […] If you do have symptoms, they usually start 4 to 10 days after being bitten by an infected mosquito. […] Some dengue symptoms are similar to flu. […] They include: a high temperature, a severe headache, pain behind your eyes, muscle and joint pain, feeling or being sick, swollen glands, a blotchy rash made up of flat or slightly raised spots this can affect large areas of your body. […] Some people get a more severe type of dengue a few days after they first started feeling ill, but this is rare. […] You may start to feel better with your temperature returning to normal, but about 24 to 48 hours later you may get more serious symptoms. […] Symptoms of severe dengue include: severe tummy pain, repeatedly being sick, fast breathing, bleeding gums or nose, extreme tiredness (fatigue), being unable to relax (restlessness), blood in your vomit or poo. […] Severe dengue can be very serious if it’s not treated quickly in hospital.
  • #1 Dengue Fever | CommonSpirit Health
    https://www.commonspirit.org/conditions-treatments/dengue-fever
    Dengue (say „DEN-gay”) fever is a disease caused by a virus that is carried by mosquitoes. Mild cases cause a rash and flu-like symptoms. Some people, especially children, can get more serious forms of the illness, known as dengue hemorrhagic fever and dengue shock syndrome. […] Symptoms of dengue fever may be mild or severe. In mild cases, common symptoms include: A sudden high fever, up to 106 F (41 C). A headache. Eye pain. Joint and muscle pain. A rash. Nausea, vomiting, and loss of appetite. The fever usually lasts up to a week and may come and go. […] After the initial fever, some people may have more serious symptoms that may be signs of dengue hemorrhagic fever. These can include: Signs of bleeding, such as: Red patches that may look like bruises or tiny red spots. Bleeding from the nose, mouth, or gums. Vomiting blood. Stools that look like black tar. Severe belly pain. Signs of shock.
  • #1 Dengue Fever > Fact Sheets > Yale Medicine
    https://www.yalemedicine.org/conditions/dengue-fever
    Usually, symptoms last for two to seven days. […] Around 1 out of every 20 people with dengue develop severe dengue. Severe dengue is a life-threatening condition and a medical emergency. Dengue can develop into severe dengue over the course of only a few hours. Warning signs of severe dengue may occur 24 to 48 hours after the fever goes away. […] Symptoms of severe dengue include: Shock (a life-threatening condition in which blood pressure is low and the organs and tissues do not receive enough blood and oxygen) or accumulation of fluid in the abdominal cavity (ascites), lungs (pulmonary edema), or space between the lung and chest wall (pleural effusion) with difficulty breathing. […] Severe bleeding. […] Severe organ involvement that can lead to impaired consciousness (lower than normal responsiveness to touch, sound, or other stimuli) and organ failure.
  • #1 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    Symptoms include rapidly rising hematocrit, intense abdominal pain, persistent vomiting, and narrowed or absent blood pressure. […] The treatment approach for dengue fever varies depending on the patient’s illness phase. […] Patients presenting with warning signs of the disease, severe dengue fever, or having risk factors such as age, pregnancy status, diabetes mellitus, or those who are living alone should be evaluated for hospitalization. […] The clinical diagnosis of dengue fever can be challenging as many other illnesses can present similarly early in the disease course. […] Untreated severe dengue fever may have a mortality rate of 10% to 20%. However, with appropriate supportive care, the mortality rate can be reduced to approximately 1%. […] Complications of dengue fever may include liver injury, cardiomyopathy, pneumonia, orchitis, oophoritis, seizures, encephalopathy, and encephalitis.
  • #1 Dengue Fever in Children: Symptoms, Diagnosis, Treatment, Prevention | Pantai Hospital
    https://www.pantai.com.my/medical-specialties/paediatrics/dengue-fever
    Dengue fever typically causes milder symptoms in younger children and those who are infected for the first time. Moderate to severe symptoms may occur in older children, adults, and those who have previously been infected. […] The following are some typical symptoms of dengue fever: Sudden onset of high fever (40C/104F) […] Fever is the most typical sign of dengue. […] Fever occurs on the 3rd to 14th day after being bitten by an infected mosquito. […] High fever typically lasts for 2 to 7 days. […] High fever can cause convulsion in children below 6 years old. […] Severe headache […] Pain behind the eyes […] Severe pain in the bones, muscle ache, and joint pain […] Bodily rash […] The most tell-tale sign of dengue fever is the rash that often develops and covers most of the body.
  • #1 Dengue – Infectious Diseases – Merck Manual Professional Edition
    https://www.merckmanuals.com/professional/infectious-diseases/arboviruses-arenaviridae-and-filoviridae/dengue
    Sore throat, gastrointestinal symptoms (eg, nausea, vomiting), and hemorrhagic symptoms can occur. Some patients develop dengue hemorrhagic fever. […] Mild cases of dengue, usually lacking lymphadenopathy, remit in 72 hours. In more severe disease, asthenia may last several weeks. Death is rare. Immunity to the infecting strain is long-lasting, whereas broader immunity to other strains lasts only 2 to 12 months. […] More severe disease may result from antibody-dependent enhancement of infection, in which patients have a non-neutralizing antibody from a previous infection with one dengue serotype and then have another infection with a different dengue serotype.
  • #1 What Is the First Sign of Dengue Fever?
    https://www.emedicinehealth.com/ask_what_is_the_first_sign_of_dengue_fever/article_em.htm
    The symptoms may last about one to two weeks with complete recovery, in most cases, in a few weeks. However, some people can develop more severe symptoms and complications, such as hemorrhagic areas in the skin (easy bruising), gums, and the gastrointestinal tract. This condition is termed dengue hemorrhagic fever (DHF). The majority of DHF is seen in children under 15 years of age, but it can occur in adults. Another clinical variation of dengue fever is termed dengue shock syndrome (DSS); DHF usually precedes DSS. The patients eventually develop severe abdominal pain, heavy bleeding, and blood pressure drops; this syndrome, if not treated quickly, may cause death.
  • #1 Dengue 
    https://www.sandiegocounty.gov/content/sdc/hhsa/programs/phs/community_epidemiology/dc/dengue.html
    These warning signs usually begin 24-48 hours after the fever has gone away. People who have had dengue before are at greater risk of severe dengue illness. […] For infants, watch for signs of dehydration, such as peeing less often; a dry mouth, tongue, or lips; few or no tears when crying; and sunken soft spots of the head or eyes. If these symptoms appear, contact your child’s doctor right away. If your baby shows severe dehydration, which includes sleepiness or low on energy; sunken eyes; cold or discolored hands or feet; and only peeing once or twice a day, go to an urgent care or emergency room immediately.
  • #1 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Initial symptoms of dengue last three to seven days. Most people begin to feel better after this, but some have life-threatening severe dengue that requires treatment in a medical facility. […] If you have symptoms of dengue fever, you have about a 1 in 20 chance of it worsening to severe dengue. If you have severe dengue and are treated immediately at a hospital or medical facility, you have a greater than 99% chance of recovering. […] Yes. Because there are at least four versions (strains) of the dengue virus, you can get dengue more than once. You’ll usually become immune to the first strain you get sick with and cant get it again. But you can get sick with one of the other three strains after that. In fact, you’re more likely to get severely sick if you get dengue more than once.
  • #1 Dengue fever: What to know and do – Harvard Health
    https://www.health.harvard.edu/blog/dengue-fever-what-to-know-and-do-202407313062
    About one in 20 people who gets sick will develop severe dengue, which requires emergency care. Those at an increased risk for severe dengue include infants a year or younger, pregnant women, adults ages 65 years or older, and those with previous dengue infections. […] Symptoms of severe dengue require immediate medical care. They include: feeling very weak and lightheaded from low blood pressure, bleeding from the nose or gums, stomach swelling, vomiting, extreme fatigue. […] Milder dengue symptoms typically last two to seven days, according to the Centers for Disease Control and Prevention (CDC). The symptoms are managed supportively: plenty of fluids, over-the-counter pain medications, and rest. […] Severe dengue usually requires treatment in a hospital with intravenous (IV) fluids. Patients are monitored until their fever breaks and symptoms begin to wane. This usually happens in about three to five days. Recovery at home can last many more days before a person’s strength returns.
  • #1 Dengue Fever – Symptoms, Causes, Diagnosis and Treatment PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact Number f
    https://www.pacehospital.com/dengue-fever-causes-symptoms-and-treatments
    The signs of dengue fever typically last for 2–7 days. Most people will recover after about a week. However, some people may develop severe dengue, which can be life-threatening. […] In most cases, the platelet count in dengue will increase around day 7 of the illness. However, the platelet count can take up to 10 days to return to normal. Sometimes, the platelet count may not return to normal even after ten days.
  • #1 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Dengue fever symptoms start to appear four to 10 days after a mosquito bite and can last three to seven days. About 1 in 20 people sick with dengue will develop severe dengue after their initial symptoms begin to fade. […] Severe dengue is a life-threatening worsening of dengue symptoms. Warning signs of severe dengue are usually seen 24 to 48 hours after your fever goes away. […] Severe dengue is a medical emergency that can be fatal. If you have dengue or live in an area where dengue is common, go to the nearest ER immediately if you experience any of these symptoms: Stomach/abdominal pain. Frequent vomiting. Throwing up blood or blood in your poop (stool). Nose bleeds or bleeding gums. Extreme tiredness, restlessness or irritability. […] Most cases of dengue fever dont have symptoms or the symptoms are mild, but sometimes you can have a more serious case that requires immediate medical attention.
  • #1 Persistent Symptoms of Dengue: Estimates of the Incremental Disease and Economic Burden in Mexico
    https://pmc.ncbi.nlm.nih.gov/articles/PMC4856607/
    Dengue is mostly considered an acute illness with three phases: febrile, critical with possible hemorrhagic manifestations, and recovery. But some patients present persistent symptoms, including fatigue and depression, as acknowledged by the World Health Organization. […] Persistent symptoms represent annually about US$22.6 million in incremental costs and 28.2 additional disability-adjusted life years per million population, or 13% and 43% increases over previous estimates, respectively. […] A symptomatic episode usually comprises a febrile phase (with fever of at least 38.5C), a critical phase around defervescence (which may include hemorrhagic manifestations and/or dengue shock syndrome), and a recovery or convalescent phase. However, some dengue patients present persistent symptoms including fatigue, depression, and weight loss after the recovery phase, a possibility acknowledged by the World Health Organization (WHO) since 1997.
  • #1 Dengue fever – Diagnosis and treatment – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/dengue-fever/diagnosis-treatment/drc-20353084
    Diagnosing dengue fever can be difficult because its signs and symptoms can be easily confused with those of other diseases such as chikungunya, Zika virus, malaria and typhoid fever. […] While recovering from dengue fever, drink plenty of fluids. Call your doctor right away if you have any of the following signs and symptoms of dehydration: Decreased urination, Few or no tears, Dry mouth or lips, Lethargy or confusion, Cold or clammy extremities. […] If you have severe dengue fever, you may need: Supportive care in a hospital, Intravenous (IV) fluid and electrolyte replacement, Blood pressure monitoring, Transfusion to replace blood loss.
  • #1 Dengue (dengue fever)
    https://www2.hse.ie/conditions/dengue-fever/
    Symptoms of dengue fever usually start suddenly, about 5 to 8 days after you become infected. […] Symptoms can include: a temperature of 38 degrees Celsius or above, feeling hot or shivery, a severe headache, pain behind your eyes, muscle and joint pain, feeling sick, vomiting, a widespread red rash, tummy pain and loss of appetite. […] The symptoms normally pass after about 1 week. But you may feel tired and a little unwell for a few weeks afterwards. […] In rare cases, severe dengue fever can develop after the initial symptoms. […] In rare cases, dengue fever can be very serious and potentially life-threatening. This is called severe dengue or dengue haemorrhagic fever. […] You may be most at risk of severe dengue fever if you had dengue before and get infected again. […] Emergency action required: Call 112 or 999 if you have symptoms of severe dengue fever such as: severe tummy pain, a swollen tummy, being sick repeatedly and vomiting blood, bleeding gums or bleeding under the skin, breathing difficulties or fast breathing, cold, clammy skin, a weak but fast pulse, drowsiness or loss of consciousness.
  • #1 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Dengue fever is an illness spread by the bite of mosquitos infected with one of the dengue viruses. Symptoms are usually flu-like but can worsen to severe dengue (dengue hemorrhagic fever), a life-threatening condition. Getting infected a second time increases your risk of serious symptoms. […] Symptoms of dengue are rash, eye pain, nausea or vomiting and muscle pain. If you live in or are visiting an area where dengue is common, seek medical attention immediately if you have warning signs of severe dengue. This includes abdominal pain, blood in your vomit or poop, bleeding gums or nose, frequent vomiting or extreme tiredness or restlessness. […] Most dengue infections dont cause symptoms. If you do have symptoms, high fever (104F/40C) is typical, along with: Rash. Intense pain behind your eyes. Nausea or vomiting. Muscle, bone and joint pain.
  • #1 VI Department of Health Encourages Public to Know the Symptoms of Dengue – VI Department of Health
    https://doh.vi.gov/vi-department-of-health-encourages-public-to-know-the-symptoms-of-dengue/
    VI Department of Health Encourages Public to Know the Symptoms of Dengue […] U.S. VIRGIN ISLANDS VI Health Commissioner Justa Encarnacion is encouraging the public to become familiar with the symptoms of dengue, the mosquito-borne virus, and the best courses of action for treatment. […] According to the CDC, dengue viruses and the virus that causes COVID-19 can have similar symptoms in the early stages, said Commissioner Encarnacion. Its important that everyone understands the difference between the two and how to treat the symptoms of dengue. […] The most common symptom of dengue is fever with any of the following: nausea, vomiting, rash, aches, and pains (eye pain, typically behind the eyes, muscle, joint, or bone pain). Symptoms of dengue typically last two to seven days and most people will recover after about a week. The mosquito that spreads dengue bites mostly at dawn and dusk.
  • #1
    https://www.health.nsw.gov.au/Infectious/factsheets/Pages/dengue.aspx
    There is no specific treatment for dengue fever. Patients should seek medical advice, rest and drink plenty of fluids. Paracetamol can be taken to bring down fever and reduce joint pains. However, aspirin or ibuprofen should not be taken since they can increase the risk of bleeding. […] For severe dengue, emergency medical care is required for close monitoring and treatment in hospital.
  • #2 Dengue fever – UF Health
    https://ufhealth.org/conditions-and-treatments/dengue-fever
    Dengue fever begins with a sudden high fever, often as high as 105F (40.5C), 4 to 7 days after the infection. […] A flat, red rash may appear over most of the body 2 to 5 days after the fever starts. A second rash, which looks like the measles, appears later in the disease. Infected people may have increased skin sensitivity and are very uncomfortable. […] Symptoms of severe dengue can occur 24 to 48 hours after fever has gone away. Severe symptoms include: Severe stomach pain and tenderness, Vomiting often (at least 3 times in 24 hours), Bleeding from the nose or gums, Vomiting blood or passing blood in the stools or urine, Bleeding under the skin (looks like bruises), Difficulty breathing, rapid breathing, Feeling tired, restless, or irritable. […] Mild cases of dengue generally last a week or more. Although uncomfortable, mild dengue fever is not deadly. People with the condition should fully recover. In some Latin American and Asian countries, severe dengue is a leading cause of death and severe illness. Early detection and treatment of severe dengue can greatly reduce the risk of death.
  • #2 Dengue | RIVM
    https://www.rivm.nl/en/dengue
    Dengue is also known as breakbone fever, because the disease can cause symptoms such as fever and joint pain. […] Most people with a dengue virus infection do not have any symptoms. People with a less severe case of dengue may have several of these symptoms in combination: sudden fever (up to 41C) with chills, headache, especially behind the eyes, muscle pain and joint pain, feeling ill, skin rash, nausea, vomiting, coughing, sore throat. […] Most people with non-severe dengue virus infections recover within a few days or a week. A small percentage of patients develop severe dengue 2 to 5 days after becoming ill. The symptoms of severe dengue can include: dark-red, bumpy rash, nosebleeds, bleeding gums, shock or fainting. […] Without treatment, severe dengue can be life-threatening. People who have had dengue before are more likely to develop severe dengue.
  • #2 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    The 3 phases of dengue fever include febrile, critical, and recovery stages. […] During the febrile phase, individuals typically experience a sudden onset of high-grade fever, reaching approximately 40 C, which usually lasts for 2 to 7 days. […] During the critical phase, defervescence marks a period when the temperature typically decreases to approximately 37.5 to 38 C or lower, occurring between days 3 and 7. […] The recovery phase involves the gradual reabsorption of extravascular fluid over 2 to 3 days. […] Expanded dengue virus syndrome refers to unusual or atypical manifestations seen in patients with involvement of various organs such as neurological, hepatic, and renal. […] Common laboratory findings include thrombocytopenia, leukopenia, and elevated levels of aspartate aminotransferase.
  • #2 Dengue fever – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/dengue-fever/symptoms-causes/syc-20353078
    Dengue fever causes a high fever 104 F (40 C) and any of the following signs and symptoms: […] When symptoms do occur, they may be mistaken for other illnesses such as the flu and usually begin four to 10 days after you are bitten by an infected mosquito. […] Most people recover within a week or so. In some cases, symptoms worsen and can become life-threatening. This is called severe dengue, dengue hemorrhagic fever or dengue shock syndrome. […] Severe dengue happens when your blood vessels become damaged and leaky. And the number of clot-forming cells (platelets) in your bloodstream drops. This can lead to shock, internal bleeding, organ failure and even death. […] Warning signs of severe dengue fever which is a life-threatening emergency can develop quickly. The warning signs usually begin the first day or two after your fever goes away, and may include: Severe stomach pain, Persistent vomiting, Bleeding from your gums or nose, Blood in your urine, stools or vomit, Bleeding under the skin, which might look like bruising, Difficult or rapid breathing, Fatigue, Irritability or restlessness.
  • #2 Understanding Dengue Fever | Saint Luke’s Health System
    https://www.saintlukeskc.org/health-library/understanding-dengue-fever
    Mild dengue infection may have few symptoms. Moderate to severe dengue has 3 phases: febrile, critical, and recovery. […] Symptoms of the febrile phase last 3 to 7 days and include: Sudden high fever, Skin redness or red patches on the skin, Severe headache, Pain behind the eyes, Severe joint and muscle pain, Upset stomach (nausea), Vomiting, Easy bruising and bleeding. […] The critical phase often lasts 2 to 3 days. During this time, body temperature may return to normal. Symptoms of the critical phase include: Vomiting that wont stop, Severe pain in the belly (abdomen), Fluid in the chest and belly, Fast breathing, Low blood pressure, Bleeding. […] A person with severe dengue may have trouble breathing, severe bleeding, damage to organs, or dengue shock syndrome. This can be fatal, and is a medical emergency. […] During the recovery phase, there is overall improvement. There may also be a rash and itchy skin. There may be heart and lung problems.
  • #2
    https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue
    Most people who get dengue will not have symptoms. But for those who do, the most common symptoms are high fever, headache, body aches, nausea, and rash. Most will get better in 12 weeks. Some people develop severe dengue and need care in a hospital. […] In severe cases, dengue can be fatal. […] Most people with dengue have mild or no symptoms and will get better in 12 weeks. Rarely, dengue can be severe and lead to death. […] If symptoms occur, they usually begin 4-10 days after infection and last for 2-7 days. Symptoms may include: high fever (40C/104F), severe headache, pain behind the eyes, muscle and joint pains, nausea, vomiting, swollen glands, rash. […] Individuals who are infected for the second time are at greater risk of severe dengue. […] Severe dengue symptoms often come after the fever has gone away: severe abdominal pain, persistent vomiting, rapid breathing, bleeding gums or nose, fatigue, restlessness, blood in vomit or stool, being very thirsty, pale and cold skin, feeling weak. […] People with these severe symptoms should get care right away. […] After recovery, people who have had dengue may feel tired for several weeks.
  • #2 Dengue – Infectious Diseases – Merck Manual Professional Edition
    https://www.merckmanuals.com/professional/infectious-diseases/arboviruses-arenaviridae-and-filoviridae/dengue
    Dengue fever usually results in abrupt onset of high fever, headache, myalgias, arthralgias, and generalized lymphadenopathy, followed by a rash that appears with a recurrent fever after an afebrile period. […] After an incubation period of 3 to 15 days, fever, chills, headache, retro-orbital pain with eye movement, lumbar backache, and severe prostration begin abruptly. Extreme aching in the legs and joints occurs during the first hours, accounting for the traditional name of breakbone fever. The temperature rises rapidly to up to 40 C, with relative bradycardia. Bulbar and palpebral conjunctival injection and a transient flushing or pale pink macular rash (particularly of the face) may occur. Cervical, epitrochlear, and inguinal lymph nodes are often enlarged. […] Fever and other symptoms persist 48 to 96 hours, followed by rapid defervescence with profuse sweating. Patients then feel well for about 24 hours, after which fever may occur again (saddleback pattern), typically with a lower peak temperature than the first. Simultaneously, a blanching maculopapular rash spreads from the trunk to the extremities and face.
  • #2 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Dengue fever symptoms start to appear four to 10 days after a mosquito bite and can last three to seven days. About 1 in 20 people sick with dengue will develop severe dengue after their initial symptoms begin to fade. […] Severe dengue is a life-threatening worsening of dengue symptoms. Warning signs of severe dengue are usually seen 24 to 48 hours after your fever goes away. […] Severe dengue is a medical emergency that can be fatal. If you have dengue or live in an area where dengue is common, go to the nearest ER immediately if you experience any of these symptoms: Stomach/abdominal pain. Frequent vomiting. Throwing up blood or blood in your poop (stool). Nose bleeds or bleeding gums. Extreme tiredness, restlessness or irritability. […] Most cases of dengue fever dont have symptoms or the symptoms are mild, but sometimes you can have a more serious case that requires immediate medical attention.
  • #2
    https://www.who.int/news-room/questions-and-answers/item/dengue-and-severe-dengue
    Dengue causes flu-like symptoms and lasts for 2-7 days. Dengue fever usually occurs after an incubation period of 4-10 days after the bite of the infected mosquito. […] High Fever (40 C/104 F) is usually accompanied by at least two of the following symptoms: headaches, pain behind eyes, nausea, vomiting, swollen glands, joint, bone or muscle pains, rash. […] Individuals infected for the second time are at greater risk of severe dengue. When developing into severe dengue, the critical phase takes place around 3-7 days after the first sign of illness. Temperature will decrease; this does not mean the person is necessarily recovering. On the other hand, special attention needs to be given to these warning signs as it could lead to severe dengue: severe abdominal pain, persistent vomiting, bleeding gums, rapid breathing, fatigue/restlessness, blood in vomit or stool, being very thirsty, pale and cold skin.
  • #2 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    Dengue begins abruptly after a typical incubation period of 57 days, and the course follows 3 phases: febrile, critical, and recovery. […] Early clinical findings are nonspecific. Dengue requires a high index of suspicion because recognizing early signs of shock and promptly initiating intensive supportive therapy with intravenous fluids can reduce risk of death among patients with severe dengue to 0.5%. […] Fever typically lasts 27 days and can be biphasic. Other signs and symptoms may include severe headache, retro-orbital pain, myalgia and arthralgia, macular or maculopapular rash; and minor hemorrhagic manifestations including petechia, ecchymosis, purpura, epistaxis, gingival bleeding, hematuria, or a positive tourniquet test result. […] Warning signs of progression to severe dengue usually occur in the late febrile phase around the time of defervescence, and include persistent vomiting, severe abdominal pain, fluid accumulation, mucosal bleeding, lethargy/restlessness, postural hypotension, liver enlargement, and progressive increase in hematocrit (i.e., hemoconcentration).
  • #2 Clinical Features of Dengue | Dengue | CDC
    https://www.cdc.gov/dengue/hcp/clinical-signs/index.html
    The recovery-phase rash may desquamate and be pruritic. […] Dengue warning signs include abdominal pain or tenderness, persistent vomiting, clinical fluid accumulation, mucosal bleeding, lethargy, restlessness, and liver enlargement. Patients with warning signs should be monitored closely as they can be more likely to progress to severe disease. […] Severe dengue is defined by dengue with any of the following clinical manifestations: severe plasma leakage leading to shock or fluid accumulation with respiratory distress; severe bleeding; or severe organ impairment such as hepatitis (elevated transaminases 1,000 IU/L), impaired consciousness, or heart impairment.
  • #2 Dengue fever – Wikipedia
    https://en.wikipedia.org/wiki/Dengue_fever
    The febrile phase involves high fever (40 C/104 F), and is associated with generalized pain and a headache; this usually lasts two to seven days. There may also be nausea, vomiting, a rash, and pains in the muscle and joints. […] Most people recover within a week or so. In about 5% of cases, symptoms worsen and can become life-threatening. This is called severe dengue. Severe dengue can lead to shock, internal bleeding, organ failure and even death. […] Warning signs include severe stomach pain, vomiting, difficulty breathing, and blood in the nose, gums, vomit or stools. During this period, there is leakage of plasma from the blood vessels, together with a reduction in platelets. This may result in fluid accumulation in the chest and abdominal cavity as well as depletion of fluid from the circulation and decreased blood supply to vital organs. […] The recovery phase usually lasts two to three days. The improvement is often striking, and can be accompanied with severe itching and a slow heart rate.
  • #2 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    Dengue fever is the leading cause of arthropod-borne viral disease worldwide, posing a significant global health concern. This disease is also known by various monikers, such as breakbone or 7-day fever, and is characterized by intense muscle spasms, joint pain, and high fever, reflecting both the severity and the duration of symptoms. […] Although most dengue fever cases are asymptomatic, severe illness and mortality can occur. […] The typical incubation period for the disease is 4 to 7 days, with symptoms lasting from 3 to 10 days. Symptoms appearing more than 2 weeks after exposure are unlikely to be attributed to dengue fever. […] The presentation of dengue fever, whether asymptomatic, typical, or severe, is influenced by a complex interplay of host and viral factors. Severe dengue fever, characterized by heightened microvascular permeability and shock syndrome, is often associated with infection by a second dengue virus serotype and the patient’s immune response.
  • #2 What is Dengue Fever? | Johns Hopkins | Bloomberg School of Public Health
    https://publichealth.jhu.edu/2024/what-is-dengue-fever
    About 75% of people who are infected with dengue have what we call subclinical symptoms, meaning they may have a fever for a day or so and feel achy, but not sick enough to seek medical care. But about 25% of people have much more severe symptoms. They have a high fever, no appetite, severe achiness, and a very low platelet count, which can result in bleeding. Around 5% of people infected with dengue have very severe illness that results in what we call plasma leakage, meaning they can’t maintain their blood pressure, and can go into shock. Those are the cases we really worry about. […] The reason we see health care systems overrun during a dengue outbreak is that we can’t predict who’s going to develop that very severe form of dengue. We tend to hospitalize a lot of people, mostly to monitor them, and try to prevent them from going on to that stage.
  • #2 Dengue Fever > Fact Sheets > Yale Medicine
    https://www.yalemedicine.org/conditions/dengue-fever
    Symptoms include fever, headache, pain behind the eyes, joint and muscle aches, nausea, vomiting, rash, swollen lymph nodes. […] Most people who become infected do not develop symptoms or instead have mild symptoms, such as fever, headache, pain behind the eyes, nausea, vomiting, and/or rash. Dengue is sometimes called breakbone fever because, in addition to fever, it can cause severe aches and pains, especially in the legs, joints, and back (dengue does not actually cause bones to break). […] However, if symptoms do occur, they typically include: Fever (usually begins four to seven days after getting bitten by an infected mosquito), Pain behind the eyes, Muscle, joint, or bone pain, Nausea and vomiting, Swollen lymph nodes, Rash (two to five days after a fever begins, a flat, red rash may develop; three to six days after a fever begins, a second rash of raised bumps may appear).
  • #2 Dengue Fever Symptoms | 7 Warning Signs of Dengue Fever | Lal PathLabs Blog
    https://www.lalpathlabs.com/blog/7-warning-signs-of-dengue-fever/
    Dengue fever usually causes a sudden high fever of up to 41 C (106 F), along with the following 7 early signs of dengue fever: Severe Headache, Muscle, joint or bone pain, Vomiting, Nausea, Skin rash (usually two to five days after the initial fever), Swollen glands, Pain behind the eyes. […] Most cases of dengue fever get better within a week. In some cases, symptoms worsen, and the condition becomes life-threatening. This is called severe dengue or dengue shock syndrome. […] In severe dengue, the blood vessels get damaged and start leaking. The number of platelets (blood clotting cells) in the blood reduces alarmingly. It can result in shock, internal bleeding, organ failure and death. […] Symptoms of severe dengue can occur suddenly and require immediate medical attention. These warning signs of dengue fever usually occur one or two days after the fever subsides and include: Severe stomach pain and stomach tenderness, Mild to severe vomiting (at least three times in 24 hours), Blood in urine, vomit or stool, Bleeding from gums or nose, Rapid breathing, Severe fatigue, Restlessness or irritability. […] Dengue symptoms can often be missed or confused with flu. Recognizing the early warning signs of dengue fever and getting treatment is essential to avoid severe dengue fever and the associated complications.
  • #2 Dengue Fever – Symptoms, Causes, Diagnosis and Treatment PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact Number f
    https://www.pacehospital.com/dengue-fever-causes-symptoms-and-treatments
    Dengue fever is a painful, debilitating mosquito-borne disease caused by any one of four closely related dengue viruses. These viruses are related to the viruses that cause West Nile infection and yellow fever. […] Signs and symptoms, which usually begin four to six days after infection and last for up to 10 days, may include: Sudden, high fever (105 degree), Severe headaches, Pain behind the eyes, Severe joint and muscle pain, Fatigue, Nausea & Vomiting, Diarrhoea, Skin rash, which appears two to five days after the onset of fever, Mild bleeding (such a nose bleed, bleeding gums, or easy bruising). […] Sometimes, dengue fever symptoms are mild and can be mistaken for those of the flu or another viral infection. Younger children and people who have never had the infection before tend to have milder cases than older children and adults.
  • #2
    https://www.who.int/news-room/questions-and-answers/item/dengue-and-severe-dengue
    People with these severe symptoms should get care right away. Severe dengue can cause: plasma leaking that may lead to shock and/or fluid accumulation with/without respiratory distress; severe bleeding; and severe organ impairment. […] For people with severe dengue, hospitalization is often needed.
  • #2 Symptoms of Dengue and Testing | Dengue | CDC
    https://www.cdc.gov/dengue/signs-symptoms/index.html
    The most common symptom of dengue is fever with any of the following: Aches and pains (eye pain, typically behind the eyes, muscle, joint, or bone pain), Nausea, vomiting, Rash, Any warning sign. […] Symptoms of dengue typically last 27 days. […] Most people will recover after about a week. […] Symptoms of dengue can become severe within a few hours. Severe dengue is a medical emergency. […] About 1 in 20 people who get sick with dengue will develop severe dengue. Severe dengue can result in shock, internal bleeding, and death. […] Watch for warning of severe dengue. Warning signs usually begin in the 24-48 hours after fever has gone away.
  • #2 VI Department of Health Encourages Public to Know the Symptoms of Dengue – VI Department of Health
    https://doh.vi.gov/vi-department-of-health-encourages-public-to-know-the-symptoms-of-dengue/
    Individuals experiencing dengue symptoms should contact their primary care doctor and get tested for the virus with a blood test, said Commissioner Encarnacion. Rest as much as possible and take acetaminophen. Do not take aspirin or ibuprofen. […] About one (1) in 20 people who get sick with dengue will develop severe dengue, according to the CDC (Center for Disease Control). Infants, pregnant women, and individuals who had dengue in the past are more likely to develop severe dengue. […] Severe dengue usually occurs 24 to 48 hours after a fever has passed. Symptoms include belly pain, tenderness, vomiting (at least 3 times in 24 hours), bleeding from the nose or gums, vomiting blood, or blood in the stool, feeling tired, restless, or irritable. […] If you are experiencing the symptoms of severe dengue, go to the Emergency Room or see your healthcare provider immediately, Commissioner Encarnacion said.
  • #2
    https://www.parkwayeast.com.sg/conditions-diseases/dengue-fever/symptoms-causes
    Dengue fever is a common viral disease that spreads to people through the bite of an infected Aedes mosquito. Mild dengue fever presents itself as fever while severe dengue fever may lead to dengue shock syndrome or dengue haemorrhagic fever. […] Symptoms of dengue fever usually show up within the first week or so of being infected. The symptoms are often mild, but the disease can cause: A sudden, very high fever, Nausea, A skin rash, which usually shows up after the fever occurs, Severe headache, Severe abdominal pain, Persistent vomiting, Pain behind your eyes, Joint and muscle pain, or spasms, Bleeding from your nose or gums, Bruising, Rapid breathing, Convulsions. […] In rare cases, there is progression from dengue fever to dengue haemorrhagic fever or dengue shock syndrome. These are severe forms of dengue which can be life threatening. Symptoms of severe dengue may include: Bleeding (e.g. gum or nose bleed, black stool, blood in vomit or stool), Persistent vomiting, Abdominal pain or tenderness, Restlessness or lethargy. […] Warning signs usually begin 1 2 days after the fever has subsided. If one has any of these warning signs, seek medical attention immediately. Severe dengue is considered an emergency and requires immediate medical care.
  • #2 Dengue Fever – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK430732/
    Symptoms include rapidly rising hematocrit, intense abdominal pain, persistent vomiting, and narrowed or absent blood pressure. […] The treatment approach for dengue fever varies depending on the patient’s illness phase. […] Patients presenting with warning signs of the disease, severe dengue fever, or having risk factors such as age, pregnancy status, diabetes mellitus, or those who are living alone should be evaluated for hospitalization. […] The clinical diagnosis of dengue fever can be challenging as many other illnesses can present similarly early in the disease course. […] Untreated severe dengue fever may have a mortality rate of 10% to 20%. However, with appropriate supportive care, the mortality rate can be reduced to approximately 1%. […] Complications of dengue fever may include liver injury, cardiomyopathy, pneumonia, orchitis, oophoritis, seizures, encephalopathy, and encephalitis.
  • #2 Dengue Fever > Fact Sheets > Yale Medicine
    https://www.yalemedicine.org/conditions/dengue-fever
    Usually, symptoms last for two to seven days. […] Around 1 out of every 20 people with dengue develop severe dengue. Severe dengue is a life-threatening condition and a medical emergency. Dengue can develop into severe dengue over the course of only a few hours. Warning signs of severe dengue may occur 24 to 48 hours after the fever goes away. […] Symptoms of severe dengue include: Shock (a life-threatening condition in which blood pressure is low and the organs and tissues do not receive enough blood and oxygen) or accumulation of fluid in the abdominal cavity (ascites), lungs (pulmonary edema), or space between the lung and chest wall (pleural effusion) with difficulty breathing. […] Severe bleeding. […] Severe organ involvement that can lead to impaired consciousness (lower than normal responsiveness to touch, sound, or other stimuli) and organ failure.
  • #2 Dengue Fever (for Parents) | Nemours KidsHealth
    https://kidshealth.org/en/parents/dengue.html
    If dengue hemorrhagic fever is not treated right away, a person can have severe internal bleeding and a drop in blood pressure, and could even die. People with dengue hemorrhagic fever need medical care right away. […] Symptoms of dengue fever can start up to 2 weeks after someone gets infected. Some people infected with the virus won’t have any symptoms. Others will have symptoms for a few days to 2 weeks before getting better. […] Dengue fever usually goes away without causing lasting problems. If someone has severe symptoms, or if symptoms get worse in the first day or two after the fever goes away, get medical care right away. Severe symptoms could be due to dengue hemorrhagic fever, which is a medical emergency.
  • #2 Dengue fever: What to know and do – Harvard Health
    https://www.health.harvard.edu/blog/dengue-fever-what-to-know-and-do-202407313062
    About one in 20 people who gets sick will develop severe dengue, which requires emergency care. Those at an increased risk for severe dengue include infants a year or younger, pregnant women, adults ages 65 years or older, and those with previous dengue infections. […] Symptoms of severe dengue require immediate medical care. They include: feeling very weak and lightheaded from low blood pressure, bleeding from the nose or gums, stomach swelling, vomiting, extreme fatigue. […] Milder dengue symptoms typically last two to seven days, according to the Centers for Disease Control and Prevention (CDC). The symptoms are managed supportively: plenty of fluids, over-the-counter pain medications, and rest. […] Severe dengue usually requires treatment in a hospital with intravenous (IV) fluids. Patients are monitored until their fever breaks and symptoms begin to wane. This usually happens in about three to five days. Recovery at home can last many more days before a person’s strength returns.
  • #2 Dengue – Infectious Diseases – Merck Manual Professional Edition
    https://www.merckmanuals.com/professional/infectious-diseases/arboviruses-arenaviridae-and-filoviridae/dengue
    Sore throat, gastrointestinal symptoms (eg, nausea, vomiting), and hemorrhagic symptoms can occur. Some patients develop dengue hemorrhagic fever. […] Mild cases of dengue, usually lacking lymphadenopathy, remit in 72 hours. In more severe disease, asthenia may last several weeks. Death is rare. Immunity to the infecting strain is long-lasting, whereas broader immunity to other strains lasts only 2 to 12 months. […] More severe disease may result from antibody-dependent enhancement of infection, in which patients have a non-neutralizing antibody from a previous infection with one dengue serotype and then have another infection with a different dengue serotype.
  • #2 Dengue fever surging in US. These are symptoms you should watch for | KLAS
    https://www.8newsnow.com/news/national-news/dengue-fever-surging-in-all-50-states-these-are-symptoms-you-should-watch-for/amp/
    Dengue remains less common in the continental United States, but in the 50 states so far this year there have been three times more cases than at the same point last year. […] About 1 in 4 dengue fevers are symptomatic, the CDC says. Symptoms, if they do occur, show up typically five to seven days after infection. People often feel fever, and other flu-like symptoms, such as nausea, vomiting, aches, rashes, joint and bone pain, and headaches. […] Severe cases can involve cause serious bleeding, shock and death. In its warning Tuesday, the CDC named warning signs that signal the disease is progressing into something serious. Those warning signs include abdominal pain, persistent vomiting, mucosal bleeding, liver enlargement, and others. […] Small infants, pregnant people and the elderly are more vulnerable to severe complications. […] Repeated infections can be especially dangerous. People showing symptoms of dengue should be tested, the CDC advised doctors.
  • #2
    https://www.kkh.com.sg/patient-care/conditions-treatments/dengue-fever
    Dengue fever is an illness caused by dengue virus, which is carried and spread by the Aedes mosquitoes. These viruses cause the body to bleed easily and may affect other organ systems. The common symptoms are Fever, Headache, Muscle and joint aches, Rash-different types of rash which may itch and appears a few days after the onset of fever, Bleeding tendency- from nose, gums or other parts of the body due to low platelets. Platelets are one of the blood components which help to clot and prevent excessive bleeding. Normal levels range from 150,000 to 450,000 per millilitre. Bruises from minor knocks and bumps. […] Sometimes, dengue infection can present in a more serious form, known as Dengue Hemorrhagic Fever (DHF) or Dengue Shock Syndrome (DSS). Serious complications can occur resulting in: Widespread bleeding, Low blood pressure or shock due to bleeding or leaking blood vessels, Organ failure, Death (The risk of dying from dengue complications is very low; less than one to five percent if supportive treatment is given early).
  • #2 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] Headache, backache, myalgia […] Rash: maculopapular or flush; petechial with islands of sparing […] Retro-orbital pain […] Bleeding […] Leucopenia […] Thrombocytopenia may also occur and usually worsens when fever resolves. […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] Fever […] Bleeding manifestations (e.g. petechiae, ecchymosis, epistaxis, gum bleeding, haematemesis, or melena) […] Thrombocytopenia ( 100 X 109/L) […] Evidence of increased capillary permeability. […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion.
  • #2
    https://www.kkh.com.sg/patient-care/conditions-treatments/dengue-fever
    Blood test is done daily to assess the platelet level and concentration (as it can be normal during the first few days of fever). Blood test can also be done at the polyclinics or general practitioner (GP) clinics. […] Current hospital guidelines allow children who are well and have a rising platelet trend or platelet above 80,000 to be discharged. For adults, our doctors will assess each patient and advice on suitability for discharge. After discharge, a repeat blood test (details included with discharge letter) should be done as and when instructed by your medical team. A further week of rest at home with no strenuous physical activities may be advised as some patients may feel very tired.
  • #2 What is Dengue Fever? | Johns Hopkins | Bloomberg School of Public Health
    https://publichealth.jhu.edu/2024/what-is-dengue-fever
    It can be, although physicians in dengue-endemic areas will tell you that with proper management, nobody should die from dengue if they present [for clinical care] in time. […] Fluid resuscitation replacing lost bodily fluids is what’s key to preventing death, but it has to be done in a careful way. Your blood pressure starts to go down because the plasma in your veins has leaked out. We give fluids to help keep that blood pressure up. But just as fast as that plasma leakage happens, it can reverse. You need really experienced people who know how to treat dengue properly. And if treated properly, the mortality rate is very low, about 0.2%. […] The other thing to note is that it can take about two weeks to become symptomatic.
  • #2 Dengue Fever: Timeline for Recovery and Treatment | Passport Health
    https://www.passporthealthusa.com/2024/12/dengue-fever-timeline-for-recovery-and-treatment/
    If your symptoms are left untreated, severe dengue can lead to internal bleeding, shock, and even death. […] With treating the mild symptoms until the infection is gone you should start to feel better after about a week. […] But, it could take a few weeks for your body to feel normal again and for all of the symptoms to clear. […] As with any virus, seek medical help if your symptoms do not improve.
  • #2 Persistent Symptoms of Dengue: Estimates of the Incremental Disease and Economic Burden in Mexico
    https://pmc.ncbi.nlm.nih.gov/articles/PMC4856607/
    Fatigue, which results in decreased capacity to work, is common during the acute stage of dengue and may persist for several weeks after recovery. […] If persistent symptoms affect a non-negligible share of the population, previous studies have likely underestimated the burden of dengue. […] Persistent symptoms were usually associated with female gender and older age. […] Despite the uncertainty in our estimates, our results suggest that persistent symptoms of dengue illness may represent a substantial economic and disease burden that has not been elucidated previously.
  • #2 Dengue (dengue fever)
    https://www2.hse.ie/conditions/dengue-fever/
    Symptoms of dengue fever usually start suddenly, about 5 to 8 days after you become infected. […] Symptoms can include: a temperature of 38 degrees Celsius or above, feeling hot or shivery, a severe headache, pain behind your eyes, muscle and joint pain, feeling sick, vomiting, a widespread red rash, tummy pain and loss of appetite. […] The symptoms normally pass after about 1 week. But you may feel tired and a little unwell for a few weeks afterwards. […] In rare cases, severe dengue fever can develop after the initial symptoms. […] In rare cases, dengue fever can be very serious and potentially life-threatening. This is called severe dengue or dengue haemorrhagic fever. […] You may be most at risk of severe dengue fever if you had dengue before and get infected again. […] Emergency action required: Call 112 or 999 if you have symptoms of severe dengue fever such as: severe tummy pain, a swollen tummy, being sick repeatedly and vomiting blood, bleeding gums or bleeding under the skin, breathing difficulties or fast breathing, cold, clammy skin, a weak but fast pulse, drowsiness or loss of consciousness.
  • #2 VI Department of Health Encourages Public to Know the Symptoms of Dengue – VI Department of Health
    https://doh.vi.gov/vi-department-of-health-encourages-public-to-know-the-symptoms-of-dengue/
    VI Department of Health Encourages Public to Know the Symptoms of Dengue […] U.S. VIRGIN ISLANDS VI Health Commissioner Justa Encarnacion is encouraging the public to become familiar with the symptoms of dengue, the mosquito-borne virus, and the best courses of action for treatment. […] According to the CDC, dengue viruses and the virus that causes COVID-19 can have similar symptoms in the early stages, said Commissioner Encarnacion. Its important that everyone understands the difference between the two and how to treat the symptoms of dengue. […] The most common symptom of dengue is fever with any of the following: nausea, vomiting, rash, aches, and pains (eye pain, typically behind the eyes, muscle, joint, or bone pain). Symptoms of dengue typically last two to seven days and most people will recover after about a week. The mosquito that spreads dengue bites mostly at dawn and dusk.
  • #2
    https://www.ncid.sg/News-Events/News/Pages/What-are-the-warning-signs-of-severe-dengue-infection.aspx
    The elderly may have less aches and pains, and may present with just tiredness, sometimes accompanied by a decrease in appetite. This makes it more challenging to diagnose dengue early and to manage it well. […] You should see a doctor immediately if you suspect you have dengue. This allows for early diagnosis, as well as appropriate monitoring and supportive care if needed. It is important to consult your doctor early to manage dengue symptoms and reduce severity of the disease.
  • #2
    https://www.health.nsw.gov.au/Infectious/factsheets/Pages/dengue.aspx
    There is no specific treatment for dengue fever. Patients should seek medical advice, rest and drink plenty of fluids. Paracetamol can be taken to bring down fever and reduce joint pains. However, aspirin or ibuprofen should not be taken since they can increase the risk of bleeding. […] For severe dengue, emergency medical care is required for close monitoring and treatment in hospital.
  • #2 Dengue fever | Communicable Diseases Agency
    https://www.cda.gov.sg/professionals/diseases/dengue-fever
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion. […] There are combination tests such as dengue NS1, IgM and IgG available for laboratory diagnosis of dengue. […] Paracetamol for fever (avoid non-steroidal anti-inflammatory drugs). […] Daily platelet and haematocrit measurement when platelets drop below 100,000/mm3. […] Complete bed rest for platelet count less than 50,000/mm3.
  • #3 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Dengue fever is an illness spread by the bite of mosquitos infected with one of the dengue viruses. Symptoms are usually flu-like but can worsen to severe dengue (dengue hemorrhagic fever), a life-threatening condition. Getting infected a second time increases your risk of serious symptoms. […] Symptoms of dengue are rash, eye pain, nausea or vomiting and muscle pain. If you live in or are visiting an area where dengue is common, seek medical attention immediately if you have warning signs of severe dengue. This includes abdominal pain, blood in your vomit or poop, bleeding gums or nose, frequent vomiting or extreme tiredness or restlessness. […] Most dengue infections dont cause symptoms. If you do have symptoms, high fever (104F/40C) is typical, along with: Rash. Intense pain behind your eyes. Nausea or vomiting. Muscle, bone and joint pain.
  • #3 Dengue fever – Causes, Symptoms, treatments, how long does it last? | MedPark Hospital
    https://www.medparkhospital.com/en-US/disease-and-treatment/dengue-fever
    People with dengue fever may have no symptoms or experience high fever, headache, muscle and joint pain, nausea, vomiting, and small red or bleeding spots on the skin. […] Severe dengue fever can lead to dengue hemorrhagic fever, resulting in circulatory system failure, shock, and even death. […] Symptoms typically appear 4-10 days after being bitten by an infected mosquito and beyond the virus’s incubation period. […] In cases of a second infection with a different strain of the dengue virus, symptoms can progress to severe dengue fever (dengue hemorrhagic fever). […] There are three phases of dengue fever symptoms: […] This phase is characterized by sudden onset of high fever, typically ranging from 39-40 degrees Celsius, lasting 2-7 days. […] Most infected people do not enter this phase. It is the most crucial period for close monitoring.
  • #3 Warning signs that your dengue infection is getting worse | gov.sg
    https://www.gov.sg/explainers/warning-signs-that-your-dengue-infection-is-getting-worse
    Feeling nauseous or feverish? Or have a headache that aches from behind the eyes? […] Common symptoms of dengue fever are: Fever, Headache with pain behind the eyes, Muscle and joint aches, Rash, Nausea and vomiting. […] Dengue typically starts off with high fever, accompanied by body aches and pain. The fever typically lasts for 3-5 days. […] The second phase is known as the critical period, and it is the most crucial one to look out for. Your body temperature is coming down (below 38 degrees C), lasting for 48 hours. During this period, your body experiences fluid shifting out of circulation compartments to other body compartments. Fluid may then accumulate in the lungs or abdominal space. Your heart rate, blood pressure may fluctuate, and in severe cases, drop to very low levels that damage your vital organs, such as your kidney and liver.
  • #3 Dengue fever – UF Health
    https://ufhealth.org/conditions-and-treatments/dengue-fever
    Dengue fever begins with a sudden high fever, often as high as 105F (40.5C), 4 to 7 days after the infection. […] A flat, red rash may appear over most of the body 2 to 5 days after the fever starts. A second rash, which looks like the measles, appears later in the disease. Infected people may have increased skin sensitivity and are very uncomfortable. […] Symptoms of severe dengue can occur 24 to 48 hours after fever has gone away. Severe symptoms include: Severe stomach pain and tenderness, Vomiting often (at least 3 times in 24 hours), Bleeding from the nose or gums, Vomiting blood or passing blood in the stools or urine, Bleeding under the skin (looks like bruises), Difficulty breathing, rapid breathing, Feeling tired, restless, or irritable. […] Mild cases of dengue generally last a week or more. Although uncomfortable, mild dengue fever is not deadly. People with the condition should fully recover. In some Latin American and Asian countries, severe dengue is a leading cause of death and severe illness. Early detection and treatment of severe dengue can greatly reduce the risk of death.
  • #3 Dengue fever – Causes, Symptoms, treatments, how long does it last? | MedPark Hospital
    https://www.medparkhospital.com/en-US/disease-and-treatment/dengue-fever
    Symptoms during this phase may include: […] The recovery phase is the final stage of dengue fever. […] Individuals who have passed the febrile phase without entering the critical phase, or those who have recovered from the critical second phase for 1-2 days, will reach the recovery phase. […] During this phase, the body gradually recovers, and various symptoms of dengue fever gradually improve.
  • #3 Dengue Fever: Symptoms, Diagnosis, Treatment, and Prevention
    https://www.royalcarehospital.in/disease-and-treatment/dengue-fever/
    Most individuals infected with dengue do not exhibit symptoms. For those who do, common symptoms include high fever, headache, body aches, nausea, and rash. […] When symptoms do appear, they can be mistaken for other illnesses like the flu, typically starting four to ten days after being bitten by an infected mosquito. Dengue fever can cause a high fever of 104F (40C) along with several other symptoms, including: Headache, Muscle, bone, or joint pain, Nausea, Vomiting, Pain behind the eyes, Swollen glands, Rash. […] Most people recover within a week. In certain instances, symptoms can escalate and pose a serious threat to life, leading to a condition known as severe dengue, dengue hemorrhagic fever, or dengue shock syndrome. Severe dengue occurs when blood vessels become damaged and leaky, and the number of clot-forming cells (platelets) decreases. This can result in shock, internal bleeding, organ failure, and potentially death.
  • #3
    https://www.parkwayeast.com.sg/conditions-diseases/dengue-fever/symptoms-causes
    Dengue fever is a common viral disease that spreads to people through the bite of an infected Aedes mosquito. Mild dengue fever presents itself as fever while severe dengue fever may lead to dengue shock syndrome or dengue haemorrhagic fever. […] Symptoms of dengue fever usually show up within the first week or so of being infected. The symptoms are often mild, but the disease can cause: A sudden, very high fever, Nausea, A skin rash, which usually shows up after the fever occurs, Severe headache, Severe abdominal pain, Persistent vomiting, Pain behind your eyes, Joint and muscle pain, or spasms, Bleeding from your nose or gums, Bruising, Rapid breathing, Convulsions. […] In rare cases, there is progression from dengue fever to dengue haemorrhagic fever or dengue shock syndrome. These are severe forms of dengue which can be life threatening. Symptoms of severe dengue may include: Bleeding (e.g. gum or nose bleed, black stool, blood in vomit or stool), Persistent vomiting, Abdominal pain or tenderness, Restlessness or lethargy. […] Warning signs usually begin 1 2 days after the fever has subsided. If one has any of these warning signs, seek medical attention immediately. Severe dengue is considered an emergency and requires immediate medical care.
  • #3 Dengue Fever > Fact Sheets > Yale Medicine
    https://www.yalemedicine.org/conditions/dengue-fever
    Symptoms include fever, headache, pain behind the eyes, joint and muscle aches, nausea, vomiting, rash, swollen lymph nodes. […] Most people who become infected do not develop symptoms or instead have mild symptoms, such as fever, headache, pain behind the eyes, nausea, vomiting, and/or rash. Dengue is sometimes called breakbone fever because, in addition to fever, it can cause severe aches and pains, especially in the legs, joints, and back (dengue does not actually cause bones to break). […] However, if symptoms do occur, they typically include: Fever (usually begins four to seven days after getting bitten by an infected mosquito), Pain behind the eyes, Muscle, joint, or bone pain, Nausea and vomiting, Swollen lymph nodes, Rash (two to five days after a fever begins, a flat, red rash may develop; three to six days after a fever begins, a second rash of raised bumps may appear).
  • #3 Dengue fever: What to know and do – Harvard Health
    https://www.health.harvard.edu/blog/dengue-fever-what-to-know-and-do-202407313062
    About one in 20 people who gets sick will develop severe dengue, which requires emergency care. Those at an increased risk for severe dengue include infants a year or younger, pregnant women, adults ages 65 years or older, and those with previous dengue infections. […] Symptoms of severe dengue require immediate medical care. They include: feeling very weak and lightheaded from low blood pressure, bleeding from the nose or gums, stomach swelling, vomiting, extreme fatigue. […] Milder dengue symptoms typically last two to seven days, according to the Centers for Disease Control and Prevention (CDC). The symptoms are managed supportively: plenty of fluids, over-the-counter pain medications, and rest. […] Severe dengue usually requires treatment in a hospital with intravenous (IV) fluids. Patients are monitored until their fever breaks and symptoms begin to wane. This usually happens in about three to five days. Recovery at home can last many more days before a person’s strength returns.
  • #3 Dengue Fever in Kids | Children’s Mercy Kansas City
    https://www.childrensmercy.org/health-and-safety-resources/dengue-fever/
    A person who has dengue fever may have the following symptoms: High fever, Severe headache, Pain behind the eyes, Joint, muscle or bone pain, Rash, Mild bleeding, especially from the nose or gums, Nausea and vomiting […] Only about 25% of adults and children infected with dengue fever will have symptoms. For those who do have symptoms, dengue fever can cause a lot of pain and discomfort, but most people who get it start feeling better after a several days. Full recovery may take few weeks. […] Symptoms usually show up 4 to 10 days after a person is bitten by an infected mosquito. […] If your child has dengue fever and starts having severe symptoms, such as shortness of breath, severe bleeding, or severe pain, they need to be seen right away.
  • #3 As dengue fever rises in US, understand symptoms, transmission
    https://www.usatoday.com/story/news/health/2024/07/18/dengue-fever-us-symptoms-transmission/74373970007/
    Most people who get dengue never show symptoms. But those who do can get high fever, body aches, nausea and rash. Most recover in a couple weeks, according to the World Health Organization. […] Some infections are so severe they can require hospitalization or even, in rare instances, kill. Severe dengue occurs in about 1 in 20 infections and can include vomiting, restlessness, rapid breathing and bloody gums, nose or stool. Infants, elderly people and pregnant women are at increased risk for severe disease, the CDC said. […] Severe dengue is more likely with repeat infections. […] There are four different types of dengue virus, with immunity to each lasting only a few years.
  • #3 Dengue Fever – Symptoms, Causes, Diagnosis and Treatment PACE Hospitals – Best Hospitals in Hitech City, Hyderabad, India | Near Madhapur, Kukatpally, KPHB, Kondapur, Gachibowli, Jubilee Hills, Banjara HillsPACE Hospitals Contact Number f
    https://www.pacehospital.com/dengue-fever-causes-symptoms-and-treatments
    However, serious problems can develop. These include dengue hemorrhagic fever, a rare complication characterized by high fever, damage to lymph and blood vessels, bleeding from the nose and gums, enlargement of the liver, and failure of the circulatory system. The symptoms may progress to massive bleeding, shock, and death. This is called dengue shock syndrome (DSS). […] The patient may develop dengue hemorrhagic fever symptoms that include pain in the abdomen, persistent vomiting, change in body temperature from fever to hypothermia, irritability, confusion, and haemorrhagic manifestations. The patient might show early signs of shock, including weak pulse, restlessness, and cold clammy skin. […] Dengue shock syndrome is a serious complication of dengue infection that has a high death rate. Secondary infection with a different viral serotype causes severe dengue.
  • #3 Dengue fever | Communicable Diseases Agency
    https://www.moh.gov.sg/seeking-healthcare/overview-of-diseases/communicable-diseases/dengue
    Dengue fever is an acute febrile disease caused by the dengue virus. […] Acute onset of fever which lasts for 2 to 7 days with 2 or more of the following: […] Headache, backache, myalgia […] Rash: maculopapular or flush; petechial with islands of sparing […] Retro-orbital pain […] Bleeding […] Leucopenia […] Thrombocytopenia may also occur and usually worsens when fever resolves. […] For a diagnosis of DHF, a case must fulfil all four of the following criteria: […] Fever […] Bleeding manifestations (e.g. petechiae, ecchymosis, epistaxis, gum bleeding, haematemesis, or melena) […] Thrombocytopenia ( 100 X 109/L) […] Evidence of increased capillary permeability. […] For a diagnosis of DSS, all four criteria for DHF must be met, in addition to hypotension, narrowed pulse pressure ( 20 mm Hg) and impaired organ perfusion.
  • #3 Dengue Fever: Causes, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/17753-dengue-fever
    Dengue fever symptoms start to appear four to 10 days after a mosquito bite and can last three to seven days. About 1 in 20 people sick with dengue will develop severe dengue after their initial symptoms begin to fade. […] Severe dengue is a life-threatening worsening of dengue symptoms. Warning signs of severe dengue are usually seen 24 to 48 hours after your fever goes away. […] Severe dengue is a medical emergency that can be fatal. If you have dengue or live in an area where dengue is common, go to the nearest ER immediately if you experience any of these symptoms: Stomach/abdominal pain. Frequent vomiting. Throwing up blood or blood in your poop (stool). Nose bleeds or bleeding gums. Extreme tiredness, restlessness or irritability. […] Most cases of dengue fever dont have symptoms or the symptoms are mild, but sometimes you can have a more serious case that requires immediate medical attention.
  • #3 Persistent Symptoms of Dengue: Estimates of the Incremental Disease and Economic Burden in Mexico
    https://pmc.ncbi.nlm.nih.gov/articles/PMC4856607/
    Dengue is mostly considered an acute illness with three phases: febrile, critical with possible hemorrhagic manifestations, and recovery. But some patients present persistent symptoms, including fatigue and depression, as acknowledged by the World Health Organization. […] Persistent symptoms represent annually about US$22.6 million in incremental costs and 28.2 additional disability-adjusted life years per million population, or 13% and 43% increases over previous estimates, respectively. […] A symptomatic episode usually comprises a febrile phase (with fever of at least 38.5C), a critical phase around defervescence (which may include hemorrhagic manifestations and/or dengue shock syndrome), and a recovery or convalescent phase. However, some dengue patients present persistent symptoms including fatigue, depression, and weight loss after the recovery phase, a possibility acknowledged by the World Health Organization (WHO) since 1997.
  • #3 Dengue Fever (for Parents) | Nemours KidsHealth
    https://kidshealth.org/en/parents/dengue.html
    Dengue fever can cause fever, headaches, rashes, and pain throughout the body. Although it can be very painful, it’s usually not fatal. Most people who get it start feeling better after several days and recover fully in a couple of weeks. […] Dengue fever used to be called „breakbone fever” because of the severe bone and muscle pain it sometimes causes. While the fever does not break any bones, it can sometimes feel like it does. […] A person with dengue fever may notice: a high fever, pain behind the eyes, pain in the joints, muscles, and/or bones, a severe headache, a rash over most of the body, easy bruising. […] Some people can get a more serious form of the infection called dengue hemorrhagic fever. They’ll have the regular symptoms of dengue fever for a few days. After the fever goes down, they also might have these problems: nausea and vomiting, severe belly pain, trouble breathing, bleeding from the nose or gums, vomiting blood, or blood in their stool (poop).
  • #3
    https://www.health.nsw.gov.au/Infectious/factsheets/Pages/dengue.aspx
    There is no specific treatment for dengue fever. Patients should seek medical advice, rest and drink plenty of fluids. Paracetamol can be taken to bring down fever and reduce joint pains. However, aspirin or ibuprofen should not be taken since they can increase the risk of bleeding. […] For severe dengue, emergency medical care is required for close monitoring and treatment in hospital.