Materiały źródłowe

• #1 Prognostic and proliferative evaluation of ameloblastoma based on radiographic boundary | International Journal of Oral Science

  https://www.nature.com/articles/ijos20128

  Ameloblastoma is a benign odontogenic tumor with an aggressive biological behavior, and the surgical treatment frequently results in failure for the postoperative recurrence. […] The aim of this article was to investigate whether the proliferative ability and prognosis of ameloblastoma could be evaluated by the radiographic boundary. […] We hypothesized that ameloblastoma with an ill-defined radiographic boundary had a higher proliferative ability, and when treated by the conservative therapy, the prognosis of patients with an ill-defined radiographic boundary was significantly worse than those with well-defined ones. […] Our research showed that the prognosis of ameloblastoma was associated mainly with the method of surgical treatment, which meant that patients receiving a conservative treatment had a worse prognosis than those who received a radical one.

• #2 Ameloblastoma primary prevention – wikidoc

  https://www.wikidoc.org/index.php/Ameloblastoma_primary_prevention

  There are no primary preventive measures available for ameloblastoma. […] There are no primary preventive measures available for ameloblastoma.

• #3 Ameloblastoma of the jawbone – USZ

  https://www.usz.ch/en/disease/ameloblastoma-of-the-jawbone/

  It is difficult to prevent ameloblastoma. To date, there is little reliable knowledge about what ultimately triggers tissue proliferation. Early detection is also not possible. As an ameloblastoma does not usually cause any pain, many patients often only notice it at an advanced stage of the disease. In general, you should have swelling or pain in the jaw area checked out as early as possible. We can determine the exact cause of the symptoms and initiate appropriate treatment. This allows you to minimize complications and late effects. […] To prevent further growth, the ameloblastoma must be removed by surgery. In about a quarter of cases, the tissue overgrowth recurs, so that further surgery may be necessary.

• #4 Ameloblastoma: Symptoms, Causes, Treatment | Qwark

  https://qwarkhealth.com/conditions/ameloblastoma

  Prevention of Ameloblastoma is not well understood as the exact causes are unknown. Additionally, there are no consistent risk factors that are known to lead to Ameloblastoma. However, some measures might reduce the risk of Ameloblastoma development, including avoiding irradiation or exposure to radiation, good dental hygiene, and avoiding infections or oral injuries. […] No specific lifestyle changes have been associated with a reduced risk of Ameloblastoma development in research or evidence. However, maintaining general health practices and avoiding risk factors that could lead to diseases such as smoking or alcohol consumption may be beneficial in reducing the risk. […] Although regular dental check-ups cannot directly prevent Ameloblastoma, they can aid in early detection and treatment of oral health issues such as oral cancers, facilitating earlier and better outcomes.

• #5 Ameloblastoma: Symptoms, Causes, Treatment | Qwark

  https://qwarkhealth.com/conditions/ameloblastoma

  Prevention of Ameloblastoma is not well understood as the exact causes are unknown. Additionally, there are no consistent risk factors that are known to lead to Ameloblastoma. However, some measures might reduce the risk of Ameloblastoma development, including avoiding irradiation or exposure to radiation, good dental hygiene, and avoiding infections or oral injuries. […] No specific lifestyle changes have been associated with a reduced risk of Ameloblastoma development in research or evidence. However, maintaining general health practices and avoiding risk factors that could lead to diseases such as smoking or alcohol consumption may be beneficial in reducing the risk. […] Although regular dental check-ups cannot directly prevent Ameloblastoma, they can aid in early detection and treatment of oral health issues such as oral cancers, facilitating earlier and better outcomes.

• #6 Ameloblastoma: Symptoms, Causes, Treatment | Qwark

  https://qwarkhealth.com/conditions/ameloblastoma

  Prevention of Ameloblastoma is not well understood as the exact causes are unknown. Additionally, there are no consistent risk factors that are known to lead to Ameloblastoma. However, some measures might reduce the risk of Ameloblastoma development, including avoiding irradiation or exposure to radiation, good dental hygiene, and avoiding infections or oral injuries. […] No specific lifestyle changes have been associated with a reduced risk of Ameloblastoma development in research or evidence. However, maintaining general health practices and avoiding risk factors that could lead to diseases such as smoking or alcohol consumption may be beneficial in reducing the risk. […] Although regular dental check-ups cannot directly prevent Ameloblastoma, they can aid in early detection and treatment of oral health issues such as oral cancers, facilitating earlier and better outcomes.

• #7 Ameloblastoma: Symptoms, Causes, Treatment | Qwark

  https://qwarkhealth.com/conditions/ameloblastoma

  Tobacco and excessive alcohol use might increase the risk of developing some cancers, such as oral cancer. However, no direct evidence indicates that avoiding these substances has any association with preventing Ameloblastoma. While there is no specific association, avoiding these habits can bring significant health benefits that could prevent more commonly occurring conditions.

• #8 Ameloblastoma: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/22143-ameloblastoma

  Early treatment and careful monitoring after treatment can prevent an ameloblastoma from damaging your jaw. […] Theres no way to prevent ameloblastoma. But you can catch growths early by seeing your dentist every six months for check-ups and oral cancer screenings. Early treatment can prevent an ameloblastoma from damaging tissue in your jaw and face. […] Seeking treatment for an ameloblastoma can prevent these worst-case scenarios from happening.

• #9 Ameloblastoma: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/22143-ameloblastoma

  Early treatment and careful monitoring after treatment can prevent an ameloblastoma from damaging your jaw. […] Theres no way to prevent ameloblastoma. But you can catch growths early by seeing your dentist every six months for check-ups and oral cancer screenings. Early treatment can prevent an ameloblastoma from damaging tissue in your jaw and face. […] Seeking treatment for an ameloblastoma can prevent these worst-case scenarios from happening.

• #10 Ameloblastoma of the jawbone – USZ

  https://www.usz.ch/en/disease/ameloblastoma-of-the-jawbone/

  It is difficult to prevent ameloblastoma. To date, there is little reliable knowledge about what ultimately triggers tissue proliferation. Early detection is also not possible. As an ameloblastoma does not usually cause any pain, many patients often only notice it at an advanced stage of the disease. In general, you should have swelling or pain in the jaw area checked out as early as possible. We can determine the exact cause of the symptoms and initiate appropriate treatment. This allows you to minimize complications and late effects. […] To prevent further growth, the ameloblastoma must be removed by surgery. In about a quarter of cases, the tissue overgrowth recurs, so that further surgery may be necessary.

• #11 Maxillary ameloblastoma: results of the treatment in 11 patients | Journal of Oral Medicine and Oral Surgery

  https://www.jomos.org/articles/mbcb/full_html/2018/01/mbcb170026/mbcb170026.html

  Surgery of maxilla ameloblastoma is mutilating and the tumor propensity for recurrence high. […] In ameloblastoma surgery, achieving both the tumor recurrence prevention and a satisfactory facial reconstruction is challenging. […] Avoiding the tumor recurrence should be the major goal when patient post-surgical follow-up cannot be guaranteed. […] One of the goals of maxillary ameloblastoma surgery is the cure by performing the tumor complete removal. […] Such an approach implies sacrifice of a variable extent of osseous tissue involving the alveolar ridge, the hard palate, the maxillary sinus walls and even sometimes the orbital floor but sparing usually the tumor overlying skin and mucosa. […] Propensity of ameloblastoma to recur even after a proper surgery is another frustration in this neoplasm treatment.

• #12 Maxillary ameloblastoma: results of the treatment in 11 patients | Journal of Oral Medicine and Oral Surgery

  https://www.jomos.org/articles/mbcb/full_html/2018/01/mbcb170026/mbcb170026.html

  Surgery of maxilla ameloblastoma is mutilating and the tumor propensity for recurrence high. […] In ameloblastoma surgery, achieving both the tumor recurrence prevention and a satisfactory facial reconstruction is challenging. […] Avoiding the tumor recurrence should be the major goal when patient post-surgical follow-up cannot be guaranteed. […] One of the goals of maxillary ameloblastoma surgery is the cure by performing the tumor complete removal. […] Such an approach implies sacrifice of a variable extent of osseous tissue involving the alveolar ridge, the hard palate, the maxillary sinus walls and even sometimes the orbital floor but sparing usually the tumor overlying skin and mucosa. […] Propensity of ameloblastoma to recur even after a proper surgery is another frustration in this neoplasm treatment.

• #13 Maxillary ameloblastoma: results of the treatment in 11 patients | Journal of Oral Medicine and Oral Surgery

  https://www.jomos.org/articles/mbcb/full_html/2018/01/mbcb170026/mbcb170026.html

  Surgery of maxilla ameloblastoma is mutilating and the tumor propensity for recurrence high. […] In ameloblastoma surgery, achieving both the tumor recurrence prevention and a satisfactory facial reconstruction is challenging. […] Avoiding the tumor recurrence should be the major goal when patient post-surgical follow-up cannot be guaranteed. […] One of the goals of maxillary ameloblastoma surgery is the cure by performing the tumor complete removal. […] Such an approach implies sacrifice of a variable extent of osseous tissue involving the alveolar ridge, the hard palate, the maxillary sinus walls and even sometimes the orbital floor but sparing usually the tumor overlying skin and mucosa. […] Propensity of ameloblastoma to recur even after a proper surgery is another frustration in this neoplasm treatment.

• #14 Maxillary ameloblastoma: results of the treatment in 11 patients | Journal of Oral Medicine and Oral Surgery

  https://www.jomos.org/articles/mbcb/full_html/2018/01/mbcb170026/mbcb170026.html

  Rates of recurrence higher after conservative surgery and reaching up to 90100% support the limited role of this approach in the current management of ameloblastoma. […] In this dilemma, our opinion is that in a setting of poorly compliance of patients for post-operative follow-up such as Africa, recurrence should be regarded as the major consideration. […] Whatever the surgical modality, ameloblastoma has a potentiality for recurrence commending a strict post-surgical follow up of the ameloblastoma patient. […] In setting of patient’s poor post-surgical follow-up, wide excision with negative margins combined to a suited facial reconstruction should be the treatment of maxillary ameloblastoma whenever possible.

• #15 A case of recurrent metastatic ameloblastoma and hypercalcaemia successfully treated with carboplatin and paclitaxel: long survival and prolonged stable disease

  https://ecancer.org/en/journal/article/323-a-case-of-recurrent-metastatic-ameloblastoma-and-hypercalcaemia-successfully-treated-with-carboplatin-and-paclitaxel-long-survival-and-prolonged-stable-disease

  Ameloblastoma is the second most common odontogenic tumour that mostly involves the mandible and maxilla. Extensive surgical resection of the primary tumour with intent to cure is the mainstay of treatment for ameloblastoma and is proposed as the best approach to prevent recurrence/metastasis. […] This report may help to guide physicians to choose a systemic treatment for patients with metastatic and/or disseminated ameloblastoma. This regimen is reasonably safe, well tolerated, easy to administer, and, more importantly, can be repeated, as being used in ovarian cancer. The efficacy for this particular regimen warrants further reports from similar cases. However, in the absence of any proven effective chemotherapy and due to perceived poor prognosis of metastatic ameloblastoma, systemic chemotherapy using carboplatin plus paclitaxel should be considered a treatment option.

• #16 Prognostic and proliferative evaluation of ameloblastoma based on radiographic boundary | International Journal of Oral Science

  https://www.nature.com/articles/ijos20128

  Ameloblastoma is a benign odontogenic tumor with an aggressive biological behavior, and the surgical treatment frequently results in failure for the postoperative recurrence. […] The aim of this article was to investigate whether the proliferative ability and prognosis of ameloblastoma could be evaluated by the radiographic boundary. […] We hypothesized that ameloblastoma with an ill-defined radiographic boundary had a higher proliferative ability, and when treated by the conservative therapy, the prognosis of patients with an ill-defined radiographic boundary was significantly worse than those with well-defined ones. […] Our research showed that the prognosis of ameloblastoma was associated mainly with the method of surgical treatment, which meant that patients receiving a conservative treatment had a worse prognosis than those who received a radical one.

• #17 Maxillary ameloblastoma: results of the treatment in 11 patients | Journal of Oral Medicine and Oral Surgery

  https://www.jomos.org/articles/mbcb/full_html/2018/01/mbcb170026/mbcb170026.html

  Rates of recurrence higher after conservative surgery and reaching up to 90100% support the limited role of this approach in the current management of ameloblastoma. […] In this dilemma, our opinion is that in a setting of poorly compliance of patients for post-operative follow-up such as Africa, recurrence should be regarded as the major consideration. […] Whatever the surgical modality, ameloblastoma has a potentiality for recurrence commending a strict post-surgical follow up of the ameloblastoma patient. […] In setting of patient’s poor post-surgical follow-up, wide excision with negative margins combined to a suited facial reconstruction should be the treatment of maxillary ameloblastoma whenever possible.

• #18 Prognostic and proliferative evaluation of ameloblastoma based on radiographic boundary | International Journal of Oral Science

  https://www.nature.com/articles/ijos20128

  It seemed that the best way for treating the ameloblastoma was extensive resection of the tumor with a wide region in the normal bone. […] Many factors were related with the prognosis of ameloblastoma. […] The radiographic boundary of ameloblastoma is another useful parameter in evaluating the growth rate of the tumor. […] Ameloblastomas with ill-defined boundary are thought to have the most aggressive behavior than others, which should be treated by the radical surgery because of the higher recurrent probability. […] In our article, we raised a hypothesis that the radiographic boundary of ameloblastoma was related to the tumor’s proliferative ability and the patient’s prognosis. […] It means that we could use the radiographic boundary as a reference to the patients for choosing surgical plan, apart from the lesion size, location, patient age, clinical and pathological types, and other parameters, and avoid the overtreatment to make those patients get a better quality of life.

• #19 Prognostic and proliferative evaluation of ameloblastoma based on radiographic boundary | International Journal of Oral Science

  https://www.nature.com/articles/ijos20128

  It seemed that the best way for treating the ameloblastoma was extensive resection of the tumor with a wide region in the normal bone. […] Many factors were related with the prognosis of ameloblastoma. […] The radiographic boundary of ameloblastoma is another useful parameter in evaluating the growth rate of the tumor. […] Ameloblastomas with ill-defined boundary are thought to have the most aggressive behavior than others, which should be treated by the radical surgery because of the higher recurrent probability. […] In our article, we raised a hypothesis that the radiographic boundary of ameloblastoma was related to the tumor’s proliferative ability and the patient’s prognosis. […] It means that we could use the radiographic boundary as a reference to the patients for choosing surgical plan, apart from the lesion size, location, patient age, clinical and pathological types, and other parameters, and avoid the overtreatment to make those patients get a better quality of life.

• #20 Conservative management (marsupialization) of unicystic ameloblastoma: literature review and a case report | Maxillofacial Plastic and Reconstructive Surgery | Full Text

  https://jkamprs.springeropen.com/articles/10.1186/s40902-017-0134-0

  Conservative treatments for UA in young patients have more advantages. […] The aim of marsupialization is to reduce the size of the tumor so that a less extensive surgery is required. […] The benefits of decompression are maintenance of pulp vitality, preservation of the inferior alveolar nerve or maxillary sinus, preservation of the mandibular contour and growth, prevention of fracture of the jaw, and low risk for recurrence. […] Conservative treatment appears to be preferable in the younger age groups because it offers a better quality of life; however, the recurrence rate remains high. […] Therefore, during surgical treatment after marsupialization, careful attention should be given to removing the tumor by sufficient curettage of surrounding tissues. […] In conclusion, conservative treatment for UA in young patients has more advantages.

• #21

  https://journals.lww.com/tdoj/fulltext/2022/19040/minimally_invasive_approach_in_treatment_of.12.aspx

  Conservative treatment is appropriate as an initial approach to ameloblastoma in children and adolescents provided there is a good regular follow-up. If relapse occurs, radical surgery can be performed at maturity in order to reduce postoperative deformity maintain appearance and function. […] The surgical excision with thorough curettage (peripheral ostectomy) as a minimally invasive surgical technique represent a suitable approach for the management of ameloblastoma in young patients with good functional and esthetic outcomes. However, long-term and regular follow-up is a must to rule out recurrence. All patients should be followed up for at least 5 years.

• #22 Conservative management (marsupialization) of unicystic ameloblastoma: literature review and a case report | Maxillofacial Plastic and Reconstructive Surgery | Full Text

  https://jkamprs.springeropen.com/articles/10.1186/s40902-017-0134-0

  Conservative treatments for UA in young patients have more advantages. […] The aim of marsupialization is to reduce the size of the tumor so that a less extensive surgery is required. […] The benefits of decompression are maintenance of pulp vitality, preservation of the inferior alveolar nerve or maxillary sinus, preservation of the mandibular contour and growth, prevention of fracture of the jaw, and low risk for recurrence. […] Conservative treatment appears to be preferable in the younger age groups because it offers a better quality of life; however, the recurrence rate remains high. […] Therefore, during surgical treatment after marsupialization, careful attention should be given to removing the tumor by sufficient curettage of surrounding tissues. […] In conclusion, conservative treatment for UA in young patients has more advantages.

• #23 Curettage combined with bone cavity opening reduces recurrence of the mandibular conventional ameloblastoma and effectively preserves the mandible: a retrospective study | BMC Oral Health | Full Text

  https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-023-03660-1

  In this study, it was found that the recurrence rate of the modified conservative treatment (Cur/BCO) was lower than that of the traditional conservative treatment for managing mandibular conventional ameloblastoma. […] Thus, Cur/BCO could be considered as a viable option for the conservative treatment of mandibular conventional ameloblastoma. […] Given that conventional ameloblastoma is principally benign and rarely life-threatening, radical surgery might be considered as overtreatment and prioritizing recurrence reduction at the expense of patients quality of life does not constitute a reasonable strategic approach. […] In recent years, an increasing number of surgeons have preferred conservative surgical approaches for the treatment of conventional ameloblastoma, complemented by regular and stringent evaluation and long-term follow-up.

• #24 A conservative therapy for patient with unicystic ameloblastoma and impacted premolar using decompression combined with orthodontic treatment—a case report – Dong – Frontiers of Oral and Maxillofacial Medicine

  https://fomm.amegroups.org/article/view/53435/html

  Our findings in this case report suggest that the combination of conservative therapy and orthodontic treatment is one of an effective management option to reconstruct the occlusion of an adolescent patient with a UAM in the mandible. […] Considering the risk of recurrence of UAM, the postoperative radiographic and clinical follow-up is necessary. […] Several clinical studies reported that the jaw cystic lesions decompression surgery combined with orthodontic treatment might help preserve the permanent teeth and correct the malocclusion caused by ameloblastoma. […] The decompression technique provides an opportunity for tooth eruption, and as a result, its possible to preserve both the jaw and teeth. […] The decompression can promote the formation of new bone in the ameloblastoma region.

• #25 Dental Update – Is Less More? A conservative multidisciplinary approach to ameloblastoma

  https://www.dental-update.co.uk/content/oral-and-maxillofacial-surgery/is-less-more-a-conservative-multidisciplinary-approach-to-ameloblastoma/

  This case report outlines a novel conservative surgical approach to the management of a unicystic ameloblastoma with the use of marsupialisation, enucleation, cryotherapy and orthodontic extrusion to enable successful treatment without neurological damage or deformity. […] It has been increasingly recognized that conservative treatment of unicystic ameloblastomas, instead of wide local excision, can reduce morbidity whilst maintaining an acceptably low recurrence rate. […] The aim of marsupialisation is to reduce the size of the tumour. The decompression of the internal contents by marsupialisation promotes remodelling of bone and osteogenesis. Once the tumour volume has been sufficiently reduced in size, it can then be treated by enucleation and/or cryotherapy. This approach has the benefits of maintaining pulp vitality, the inferior alveolar nerve and preventing jaw fracture.

• #26 Curettage combined with bone cavity opening reduces recurrence of the mandibular conventional ameloblastoma and effectively preserves the mandible: a retrospective study | BMC Oral Health | Full Text

  https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-023-03660-1

  This led to the formation of an anoxic environment within the wound cavity, promoting the active growth of residual tumor cells, and ultimately contributing to the recurrence. […] The Cur/BCO technique is characterized by its approach of not closing the wound cavity and refraining from employing any adjuvant therapies during the operation. […] We hypothesize that the presence of abundant air in the bone cavity alters the micro-environment of residual tumor cells and the osteogenesis environment. This may account for the low recurrence rate of Cur/BCO.

• #27 Curettage combined with decompression for the treatment of ameloblastoma in children: report of two cases | BMC Oral Health | Full Text

  https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-024-04126-8

  Children are in the growth and development period and possess an extremely strong ability of bone formation and reconstruction. […] We believe that curettage combined with decompression can be the first choice for treating AM in children, especially for mandibular lesions. […] Given the high recurrence rate of curettage and the impact of osteotomy on growth, development, and psychology of children, we aim to use curettage combined with decompression in recent years to treat patients with classic AM who meet the indications, and satisfactory results have been achieved. […] The superiority of this approach was particularly evident in the treatment responses of the two patients aged under 10.

• #28 Curettage combined with decompression for the treatment of ameloblastoma in children: report of two cases | BMC Oral Health | Full Text

  https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-024-04126-8

  Children are in the growth and development period and possess an extremely strong ability of bone formation and reconstruction. […] We believe that curettage combined with decompression can be the first choice for treating AM in children, especially for mandibular lesions. […] Given the high recurrence rate of curettage and the impact of osteotomy on growth, development, and psychology of children, we aim to use curettage combined with decompression in recent years to treat patients with classic AM who meet the indications, and satisfactory results have been achieved. […] The superiority of this approach was particularly evident in the treatment responses of the two patients aged under 10.

• #29 Maxillary ameloblastoma: results of the treatment in 11 patients | Journal of Oral Medicine and Oral Surgery

  https://www.jomos.org/articles/mbcb/full_html/2018/01/mbcb170026/mbcb170026.html

  Rates of recurrence higher after conservative surgery and reaching up to 90100% support the limited role of this approach in the current management of ameloblastoma. […] In this dilemma, our opinion is that in a setting of poorly compliance of patients for post-operative follow-up such as Africa, recurrence should be regarded as the major consideration. […] Whatever the surgical modality, ameloblastoma has a potentiality for recurrence commending a strict post-surgical follow up of the ameloblastoma patient. […] In setting of patient’s poor post-surgical follow-up, wide excision with negative margins combined to a suited facial reconstruction should be the treatment of maxillary ameloblastoma whenever possible.

• #30 Ameloblastoma secondary prevention – wikidoc

  https://www.wikidoc.org/index.php/Ameloblastoma_secondary_prevention

  Secondary prevention strategies following ameloblastoma include follow-up examination at regular intervals for at least 10 years. […] Regular follow-up examination with the physician is very important in managing ameloblastoma. […] For ameloblastoma patients follow up should occur at regular intervals for at least 10 years.

• #31 Ameloblastoma secondary prevention – wikidoc

  https://www.wikidoc.org/index.php/Ameloblastoma_secondary_prevention

  Secondary prevention strategies following ameloblastoma include follow-up examination at regular intervals for at least 10 years. […] Regular follow-up examination with the physician is very important in managing ameloblastoma. […] For ameloblastoma patients follow up should occur at regular intervals for at least 10 years.

• #32

  https://journals.lww.com/tdoj/fulltext/2022/19040/minimally_invasive_approach_in_treatment_of.12.aspx

  Conservative treatment is appropriate as an initial approach to ameloblastoma in children and adolescents provided there is a good regular follow-up. If relapse occurs, radical surgery can be performed at maturity in order to reduce postoperative deformity maintain appearance and function. […] The surgical excision with thorough curettage (peripheral ostectomy) as a minimally invasive surgical technique represent a suitable approach for the management of ameloblastoma in young patients with good functional and esthetic outcomes. However, long-term and regular follow-up is a must to rule out recurrence. All patients should be followed up for at least 5 years.

• #33

  https://journals.lww.com/tdoj/fulltext/2022/19040/minimally_invasive_approach_in_treatment_of.12.aspx

  Conservative treatment is appropriate as an initial approach to ameloblastoma in children and adolescents provided there is a good regular follow-up. If relapse occurs, radical surgery can be performed at maturity in order to reduce postoperative deformity maintain appearance and function. […] The surgical excision with thorough curettage (peripheral ostectomy) as a minimally invasive surgical technique represent a suitable approach for the management of ameloblastoma in young patients with good functional and esthetic outcomes. However, long-term and regular follow-up is a must to rule out recurrence. All patients should be followed up for at least 5 years.

• #34 Dental Update – Is Less More? A conservative multidisciplinary approach to ameloblastoma

  https://www.dental-update.co.uk/content/oral-and-maxillofacial-surgery/is-less-more-a-conservative-multidisciplinary-approach-to-ameloblastoma/

  It is evident that, whilst these two conservative techniques are rarely employed, they do have an evidence base with demonstrated efficacy and safety. However, the use of these two techniques in conjunction, in the case of the conservative management of a unicystic ameloblastoma, is particularly novel. […] This present report adds to the limited body of literature by demonstrating efficacy of this conservative treatment in adults with unicystic ameloblastoma. […] Due to the ongoing risk of recurrence, as with any treatment of ameloblastoma, long term annual follow-up is warranted.

• #35 A conservative therapy for patient with unicystic ameloblastoma and impacted premolar using decompression combined with orthodontic treatment—a case report – Dong – Frontiers of Oral and Maxillofacial Medicine

  https://fomm.amegroups.org/article/view/53435/html

  Our findings in this case report suggest that the combination of conservative therapy and orthodontic treatment is one of an effective management option to reconstruct the occlusion of an adolescent patient with a UAM in the mandible. […] Considering the risk of recurrence of UAM, the postoperative radiographic and clinical follow-up is necessary. […] Several clinical studies reported that the jaw cystic lesions decompression surgery combined with orthodontic treatment might help preserve the permanent teeth and correct the malocclusion caused by ameloblastoma. […] The decompression technique provides an opportunity for tooth eruption, and as a result, its possible to preserve both the jaw and teeth. […] The decompression can promote the formation of new bone in the ameloblastoma region.

• #36 Ameloblastoma: Causes, Symptoms, and Treatment

  https://www.medicoverhospitals.in/diseases/ameloblastoma/

  While there are no established methods for preventing ameloblastoma, early detection and prompt treatment are essential for minimizing complications. […] There are no known preventive measures, but early detection through regular dental check-ups can aid in timely treatment.

• #37 Curettage combined with bone cavity opening reduces recurrence of the mandibular conventional ameloblastoma and effectively preserves the mandible: a retrospective study | BMC Oral Health | Full Text

  https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-023-03660-1

  In this study, it was found that the recurrence rate of the modified conservative treatment (Cur/BCO) was lower than that of the traditional conservative treatment for managing mandibular conventional ameloblastoma. […] Thus, Cur/BCO could be considered as a viable option for the conservative treatment of mandibular conventional ameloblastoma. […] Given that conventional ameloblastoma is principally benign and rarely life-threatening, radical surgery might be considered as overtreatment and prioritizing recurrence reduction at the expense of patients quality of life does not constitute a reasonable strategic approach. […] In recent years, an increasing number of surgeons have preferred conservative surgical approaches for the treatment of conventional ameloblastoma, complemented by regular and stringent evaluation and long-term follow-up.

• #38

  https://journals.lww.com/tdoj/fulltext/2022/19040/minimally_invasive_approach_in_treatment_of.12.aspx

  Treatment of ameloblastoma in young patients should be conservative to avoid serious complications resulting from radical surgery. […] Ameloblastoma in adolescents can be successfully treated conservatively by surgical excision with thorough curettage (peripheral ostectomy). […] The treatment of ameloblastoma can be classified into radical and conservative approaches, the conservative approach such as marsupialization, curettage, enucleation, cryotherapy and treatment of the operative field with chemicals such as Carnoy’s solution or thermal as cryotherapy could preserve the bone integrity and allow continued growth of the mandible. […] The enucleation and curettage of ameloblastoma represents a therapeutic strategy to avoid more invasive treatments with following reconstructive phases.

• #39 Ameloblastoma secondary prevention – wikidoc

  https://www.wikidoc.org/index.php/Ameloblastoma_secondary_prevention

  Secondary prevention strategies following ameloblastoma include follow-up examination at regular intervals for at least 10 years. […] Regular follow-up examination with the physician is very important in managing ameloblastoma. […] For ameloblastoma patients follow up should occur at regular intervals for at least 10 years.

• #40

  https://journals.lww.com/tdoj/fulltext/2022/19040/minimally_invasive_approach_in_treatment_of.12.aspx

  Conservative treatment is appropriate as an initial approach to ameloblastoma in children and adolescents provided there is a good regular follow-up. If relapse occurs, radical surgery can be performed at maturity in order to reduce postoperative deformity maintain appearance and function. […] The surgical excision with thorough curettage (peripheral ostectomy) as a minimally invasive surgical technique represent a suitable approach for the management of ameloblastoma in young patients with good functional and esthetic outcomes. However, long-term and regular follow-up is a must to rule out recurrence. All patients should be followed up for at least 5 years.

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