Materiały źródłowe

• #1 Anosmia (Loss of Smell): Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/21859-anosmia-loss-of-sense-of-smell

  Anosmia is when you cant detect odors. Its usually a temporary side effect from a cold or sinus infection that goes away when your cold or sinus infection clears. But sometimes anosmia may be symptom of other, more serious medical issues like diabetes or traumatic brain injury. […] In most cases, treating the underlying condition improves your sense of smell. For example, if you have sinusitis, antibiotics can help clear up the infection. If certain medications affect your sense of smell, switching medications may help ease your anosmia symptoms. If something is blocking your nose, like a nasal polyp, or you have a deviated septum, you may need surgery. […] Often, anosmia is a side effect of many common medical issues. Youll be able to smell again once the underlying issue goes away. Rarely, people have congenital anosmia, for which theres no known cure.

• #1 Anosmia: Causes, Complications, and Treatment

  https://www.healthline.com/health/anosmia

  Anosmia is the partial or complete loss of the sense of smell. This loss may be temporary or permanent. […] Treatment depends on the cause. If the loss of smell occurs with a cold, allergy, or sinus infection, it typically will clear up on its own in a few days. You should consult your doctor if the anosmia doesn’t clear up once the cold or allergy symptoms have subsided. […] Treatments that may help resolve anosmia caused by nasal irritation include: decongestants, antihistamines, steroid nasal sprays, antibiotics, for bacterial infections, reducing exposure to nasal irritants and allergens, cessation of smoking. […] Loss of smell caused by nasal obstruction can be treated by removing whatever is obstructing your nasal passage. This removal may involve a procedure to remove nasal polyps, straighten the nasal septum, or clear out the sinuses. […] There is no treatment currently available for people with congenital anosmia. […] People with a partial loss of their sense of smell can add concentrated flavoring agents to food to improve their enjoyment.

• #1 Healthy aging

  https://www.mayoclinic.org/healthy-lifestyle/healthy-aging/expert-answers/loss-of-taste-and-smell/faq-20058455

  Some loss of taste and smell is natural with aging, especially after age 60. […] Loss of taste and smell can have a significant impact on quality of life. It often leads to decreased appetite and poor nutrition. It can sometimes contribute to depression. Loss of taste and smell also might tempt you to use excess salt or sugar on your food to enhance the taste. This could be a problem if you have high blood pressure or diabetes. […] If you’re experiencing loss of taste and smell, see your health care provider. Some causes of impaired taste and smell are treatable. For example, your health care provider might adjust your medications if they’re contributing to the problem. Many nasal and sinus conditions and dental problems can be treated as well. If you smoke, quitting can help restore your sense of smell.

• #1 Smell (Olfactory) Disorders—Anosmia, Phantosmia & Others | NIDCD

  https://www.nidcd.nih.gov/health/smell-disorders

  People who have a smell disorder either have a decrease in their ability to smell or changes in the way they perceive odors. […] Both smell and taste disorders are treated by an otolaryngologist, a doctor who specializes in diseases of the ear, nose, throat, head, and neck (sometimes called an ENT). An accurate assessment of a smell disorder will include, among other things, a physical examination of the ears, nose, and throat; a review of your health history, such as exposure to toxic chemicals or injury; and a smell test supervised by a health care professional. […] Diagnosis by a doctor is important to identify and treat the underlying cause of a potential smell disorder. If your problem is caused by medications, talk to your doctor to see if lowering the dosage or changing the medicine could reduce its effect on your sense of smell. If nasal obstructions such as polyps are restricting the airflow in your nose, you might need surgery to remove them and restore your sense of smell. […] Some people recover their ability to smell when they recover from the illness causing their loss of smell. Some people recover their sense of smell spontaneously, for no obvious reason. If your smell disorder cant be successfully treated, you might want to seek counseling to help you adjust.

• #1 Anosmia Diagnosis and Treatment – Monell Chemical Senses Center

  https://monell.org/anosmia-diagnosis-and-treatment/

  If you have experienced a loss in your sense of smell, you should seek evaluation by a board-certified otolaryngologist (ear, nose and throat specialist), preferably at a large university medical center, to determine if the cause can be identified and if you may respond to treatment. […] Anosmia is a diverse disorder having many possible causes. Unfortunately, at the present time, there are relatively few forms of smell problems for which the underlying cause can be conclusively identified. And without knowing exactly what caused the smell loss, treatment options are limited. Finally, it often is difficult to predict who will and who won’t respond to treatment. […] Your doctor will evaluate whether you have a physical blockage that prevents odors from reaching your olfactory epithelium, the part of the nose that contains the cells that actually help the brain recognize odors.

• #1 Anosmia FAQ – Monell Chemical Senses Center

  https://monell.org/anosmia-faq/

  Anosmia – loss of the sense of smell – can occur for several different reasons. […] The only established treatments for anosmia are in cases of chronic nasal-sinus disease (see above). Therefore, it is important that you consult with an otolaryngologist (ear, nose and throat specialist) to determine if this may be the source of your anosmia. If so, possible treatment options might include: antibiotics, topical or oral corticosteroids to reduce the inflammation, or surgery to remove inflamed tissue and/or nasal polyps. […] Smell-training (twice daily exposure to several intense odors) may improve the sense of smell in some – but not all – people whose anosmia is due to viral infection, head trauma or aging. However, it is not yet known whether this is a long-term solution. […] No other treatments for anosmia have been confirmed using randomized double-blind trials, the gold standard that medical scientists use to establish a potential treatment’s effectiveness.

• #1 Smell and Taste Loss | Mass Eye and Ear

  https://masseyeandear.org/conditions/smell-taste-loss

  Smell loss happens when there is a blockage of airflow getting to the nerves responsible for detecting odors, direct damage to the nerves, or direct damage to the areas of the brain where the sense of smell is processed. […] In many cases, the cause of taste loss is unknown. The ability to treat taste loss depends on the ability to identify the cause. Your physician will evaluate the smell/taste loss through an extensive discussion of your history and by an endoscopic examination of your nasal cavity. A smell test may also be performed. If smell loss is ruled out, we administer a taste test. Depending on the results, further testing such as an MRI or CT scan may be needed. […] Unfortunately, there are not many therapies available to patients with smell loss. If infection is the underlying cause, it can be treated with antibiotic or antifungal medications. In cases where the smell loss is caused by sinus disease, medication or surgery may be helpful. Oral steroids might also help in treating certain forms of smell loss, but they may only provide a short-term benefit.

• #1 Anosmia Smell Loss Treatment Houston TX | Hyposmia Houston

  https://houstonadvancedsinus.com/rhinologic-conditions/anosmia-smell-loss/

  Anosmia, or smell loss, can be a temporary or a permanent condition. With smell loss, time is a critical factor, because the sooner treatment is initiated the more likely the sense of smell is to return. […] However, for other patients, there are interventions such as treatments with oral or topical steroids and olfactory training that may be necessary to recover smell function. […] If Dr. Kuperan suspects that a virus or bacterial infection is responsible for your smell loss, he will prescribe medication to help. If your smell loss persists, he may recommend olfactory training, which is akin to physical therapy for your nose and can help people regain their smell when medication does not work. […] An in-office procedure called balloon sinuplasty can be helpful for patients suffering from persistent sinus problems, including anosmia.

• #1 When Loss of Smell and Taste Occurs with Long COVID > News > Yale Medicine

  https://www.yalemedicine.org/news/when-loss-of-smell-and-taste-occurs-with-long-covid

  Patricia […] more than four years later, she still hasnt regained her sense of taste and smell. […] An estimated 60% of patients infected in 2021 with SARS-Co-V2, the virus that causes COVID, lost some ability to taste or smell, according to research published in 2023. […] Most patients recover their sense of smell within one to two years. For many of those who do not, anosmia can cause significant emotional distress and depression. […] Clinical treatment options for anosmia following viral infections are currently limited and demonstrate mixed results. […] However, one option for patients is smell retraining. […] At the start of the nine-month anosmia treatment program, patients will receive four scentslemon, rose, eucalyptus, and cloves. […] Perhaps of equal importance to clinical efforts to support individuals with anosmia are patient advocacy groups like Fifth Sense and abScent, which have developed extensive networks to help support individuals with anosmia and connect them with resources and guides on living healthily and safely with anosmia.

• #1 Anosmia: Symptoms, Causes, and Treatments

  https://www.webmd.com/brain/anosmia-loss-of-smell

  If nasal congestion from a cold or allergy is the cause of anosmia, treatment is usually not needed, and the problem will get better on its own. Short-term use of over-the-counter decongestants may open up your nasal passages so that you can breathe easier. However, if the congestion gets worse or does not go away after a few days, see your doctor. You may have an infection and need antibiotics, or another medical condition may be to blame. […] If a polyp or growth is present, surgery may be needed to remove the obstruction and regain your sense of smell. […] If you suspect a medication is affecting your sense of smell, talk to your doctor and see if there are other treatment options available that won’t affect your ability to smell. However, never stop taking a medication without first talking with your doctor.

• #1 Regaining your sense of taste and smell after COVID-19 | HealthPartners Blog

  https://www.healthpartners.com/blog/how-to-regain-sense-of-smell-and-taste-after-covid-19/

  COVID-19 can disrupt your senses, including your ability to taste and smell. But even after people recover, these senses dont always come back immediately or sometimes return in an unexpected way. […] Fortunately, changes to taste and smell arent forever for most people. Plus, there are treatments that may help speed recovery. […] If changes to your sense of smell stick around longer than your other COVID-19 symptoms, it might be caused by inflammation in your nose. These at-home treatments can help: […] An over-the-counter nasal steroid spray like Flonase or Nasacort may be another option to clear up sinus inflammation. […] Smell therapy can help the process involves smelling different strong scents for at least 20 seconds while thinking about memories and experiences involving the scent.

• #1 COVID-19: A potential treatment for loss of smell | INRAE

  https://www.inrae.fr/en/news/covid-19-potential-treatment-loss-smell

  One of the most persistent and debilitating symptoms of COVID19 is anosmia or loss of smell. Researchers at INRAE and ENVA have discovered that a corticoid treatment could help restore the olfactory capacities affected by the viral infection. […] Their results support the existence of a direct link between the loss of smell caused by the virus and a decrease in the olfactory neuron population in the nasal mucosa. In addition, they show that early treatment with dexamethasone, a commonly used corticosteroid, improves the recovery of olfactory abilities in animals. […] These results suggest that the corticosteroid treatments currently used which have not been very successful in the treatment of prolonged anosmia could be more effective if prescribed early, at the onset of symptoms of loss of smell.

• #1 Loss of Smell – Ear, Nose, and Throat Disorders – Merck Manual Consumer Version

  https://www.merckmanuals.com/home/ear-nose-and-throat-disorders/symptoms-of-nose-and-throat-disorders/loss-of-smell

  Doctors treat the cause of the anosmia. For example, people with sinus infections and irritation may be treated with steam inhalation, nasal sprays, antibiotics, and sometimes surgery. However, the sense of smell does not always return even after successful treatment of sinusitis. Tumors are surgically removed or treated with radiation, but such treatment usually does not restore the sense of smell. Polyps in the nose are removed, sometimes restoring the ability to smell. People who smoke tobacco should stop. […] There are no treatments for anosmia itself. People who retain some sense of smell may find that adding concentrated flavoring agents to food improves their enjoyment of eating. Smoke alarms, important in all homes, are even more essential for people with anosmia because they cannot smell smoke. Doctors recommend that people with anosmia use caution before consuming stored food and using natural gas for cooking or heating because they may have difficulty detecting food spoilage and gas leaks.

• #1 Lost or Changed Sense of Smell: Causes & Treatment – ENT LDN

  https://entlondon.org.uk/blogs/lost-or-changed-sense-of-smell-causes-and-treatment/

  2. Try Nasal Sprays […] Nasal sprays are quick and easy ways to improve airflow or nasal congestion. If used correctly, these sprays can enhance the ability to detect odours. They reduce inflammation in the nasal passage and allow mucus to loosen and clear the passage. Your doctor can initially prescribe saline nasal sprays to relieve the nasal cavity. […] 3. Rhinoplasty […] Rhinoplasty is considered a safe procedure for individuals dealing with severe nasal problems. The surgery can be a good option for those with internal structural issues who want to fix them quickly. The most common factor is a deviated septum. A misaligned wall between the nostrils can lead to soft tissue growth. Treating this condition with rhinoplasty surgery is essential as it can lead to nasal congestion and breathing problems.

• #1 Treatments | Stanford Health Care

  https://stanfordhealthcare.org/medical-conditions/ear-nose-and-throat/anosmia-loss-of-smell/treatments.html

  […] […] Surgery […] If you have a tumor, nasal polyp, deviated septum, or other obstruction thats causing smelling abnormalities, your doctor may recommend surgery. Our renowned team of head and neck surgeons has experience with a range of techniques for nasal surgery. […] We are skilled at the latest minimally invasive options, such as endoscopic sinus surgery and endoscopic endonasal surgical techniques. We perform these procedures using a thin, flexible tube inserted through the nose, so theres no need for incisions. Your care team will recommend the appropriate procedure and deliver customized care.

• #1 Smell Retraining Therapy – ENT Health

  https://www.enthealth.org/be_ent_smart/smell-retraining-therapy/

  Smell retraining therapy (SRT) is a treatment for loss of smell, also referred to as hyposmia or anosmia. It can be used to help return your sense of smell if it was lost during a viral infection or minor head trauma. SRT was originally developed in 2009 by Dr. Thomas Hummel at the University of Dresden. […] The process of SRT involves the repeated presentation of different smells through the nose to stimulate the olfactory system and establish memory of that smell. It is best to start with at least four different scents, especially smells you remember. […] SRT is believed to work as a combination of the unique ability for smell nerves to regrow while encouraging improved brain connectivity. […] Most of the studies on SRT have been done on patients with post-viral (i.e., after a cold or upper respiratory infection) smell loss. […] If you are not in that group, it may be beneficial to consider trying SRT. Even if it is not helpful, it will not worsen the problem. […] A study conducted by researchers at Stanford University showed that SRT worked better when paired with sinus rinses that included steroids.

• #1 Post-Covid, Many Patients Try Smell Therapy. But Does it Work?

  https://undark.org/2021/04/20/post-covid-many-patients-try-smell-therapy-but-does-it-work/

  In a recent episode of the popular New York Times podcast The Daily, restaurant critic Tejal Rao described her experience losing her sense of smell after having Covid-19. […] Like many others who have lost their sense of smell to the disease, Rao set off on a journey to recover her ability to detect scent, ultimately landing on an approach known as smell therapy. […] When it comes to treating olfactory dysfunction, according to the podcast notes, smell therapy is “the only therapy proven to work.” […] In response, some researchers are revisiting the concept of physical therapy for the nose in order to help restore what Covid-19 and other ailments have taken away. […] Aside from a controversial steroid nasal spray, this leaves people just one treatment option with any supporting studies: smell training.

• #1 Relearning to smell after COVID-19 | BCM

  https://www.bcm.edu/news/relearning-to-smell-after-covid-19

  Many people recovering from COVID-19 have reported prolonged loss of smell. […] Current research shows this symptom may be more common in COVID-19 patients because the SARS-CoV-2 virus binds to receptors found in the part of the nose that controls smell, according to Dr. Sunthosh Sivam, assistant professor of otolaryngology head and neck surgery at Baylor. […] If you have any type of smell at all, its a sign that your olfactory nerve is still working. […] Both doctors recommend that anyone experiencing prolonged smell loss after recovering from COVID-19 make an appointment to see an ear, nose and throat specialist to rule out other potential causes. […] Patients may be prescribed nasal steroids or rinses to address inflammation. […] If the problems persist, Sivam and Locke introduce patients to olfactory retraining. They call it physical therapy for your nose.

• #1 Regain Your Sense of Smell with Olfactory Training

  https://breathefreely.com/how-olfactory-training-can-help-you-regain-your-sense-of-smell/

  Has recovering from a viral infection left you without a sense of smell? Or maybe you’ve noticed a change in how you smell, and now aromas you used to love are making you grimace. […] This is not an uncommon side effect, and you can actually rewire your nerve fibers to smell properly again through a process called olfactory training. This is a great way to reintroduce smells to your brain. Moreover, it is cost-efficient and can be done in the comfort of your own home. […] Olfactory training can help restore your ability to smell, whether that be a total loss or just slight differences from how you used to smell. […] But you don’t have to be stuck without a sense of smell. Instead, you can practice olfactory training to rewire those nerve fibers to function correctly again. […] Olfactory training, or smell training, is a simple process you can do at home without the supervision of a doctor. This process helps to rewire the regenerated nerve fibers that went awry during a viral infection or whatever initially caused your loss of smell.

• #1 Coping with the loss of smell and taste – Harvard Health

  https://www.health.harvard.edu/blog/coping-with-the-loss-of-sense-of-smell-and-taste-2020101921141

  As I cut a slice of lemon for my tea one morning last March, I found that I could not detect the familiar zing of citrus. Nor, it turned out, could I taste the peach jam on my toast. Overnight, my senses of smell and taste seemed to have disappeared. […] The good news is that olfactory neurons are capable of regeneration. The bad news is that not everyone will return to his or her pre-COVID level of functioning. And, sadly, some of us might never regain our sense of smell or taste at all. According to some experts, patients with post-viral loss of smell have roughly a 60% to 80% chance of regaining some of their smell function within a year. […] To reawaken the olfactory nerves, most specialists recommend smell training, a daily routine of sniffing essential oils such as lemon, eucalyptus, cloves, rose, and others.

• #1 Loss of Smell: Current & Emerging Therapies

  https://www.backtable.com/shows/ent/articles/loss-of-smell-current-emerging-therapies

  Smell retraining therapy is a highly effective, evidence-based tool to help patients recover olfactory capacity. During smell retraining therapy, patients focus on what they should perceive while smelling standardized odors, thus strengthening weakened neural connections important to olfaction. […] Smell retraining therapy is an evidence-based therapy that restores smell by exercising the olfactory system. In smell retraining therapy, patients are instructed to place an odor from a sample kit under their nose twice a day and think about what the odor should smell like. […] Manifesting clinically meaningful improvements in smell requires six months of dedicated training. Parallel use of nasal steroid irrigations can improve smell retraining therapy outcomes by decreasing nasal inflammation.

• #1 How Can I Get My Sense of Smell back? – Southwest Ohio ENT Specialists

  https://soents.com/how-can-i-get-my-sense-of-smell-back/

  Simply put, SRT involves smelling very pure forms of a smell (usually from an essential oil) multiple times per day while focusing on what that item should smell like. […] A modification of this protocol (studied in 2015 by Dr. Hummel et al.) involved using more smells (12) for a long period of time (36 weeks) showed improved results.

• #1 Smell retraining therapy and long COVID | My Doctor Online

  https://mydoctor.kaiserpermanente.org/covid-19/smell-retraining-therapy-and-long-covid

  You can use smell retraining therapy (SRT) if you have loss of sense of smell due to long COVID. […] Most people with long COVID gradually regain their sense of smell, though this can take months or even longer. […] You can use SRT at home (also called olfactory training). Studies show SRT is generally effective, though results vary from person to person. […] SRT works by strengthening the nerves involved in our sense of smell. […] Some people also lose their sense of taste. SRT can help you recover this sense, as well. […] Start with 4 scents. These 4 work well for most people: rose, eucalyptus, lemon, and clove. […] After 3 months, switch to 4 new scents. Use them with the same twice-daily method. Suggestions: menthol, thyme, tangerine, and jasmine. […] After 3 more months (6 months after starting SRT), again switch to 4 new scents. Suggestions: green tea, bergamot, rosemary, and gardenia.

• #1 Post-Covid, Many Patients Try Smell Therapy. But Does it Work?

  https://undark.org/2021/04/20/post-covid-many-patients-try-smell-therapy-but-does-it-work/

  Thomas Hummel, an ear, nose, and throat doctor and a researcher at the Smell and Taste Clinic in Dresden, Germany, was the first person to test the intervention on patients in a clinic. […] The goal was to stimulate different types of smell receptors, so he selected scents from four different corners. […] In the study published by Hummel and his colleagues in 2009, about 30 percent of those who underwent smell training reported an improvement in their smell, compared to only six percent in the control group. […] Since that initial trial, more than 20 studies have demonstrated some improvement with smell training. […] But Leigh Sowerby, also an ear, nose, and throat specialist in Ontario and Rotenberg’s research colleague, noted that the degree of recovery in studies that compare to a placebo was modest.

• #1 How to Counteract Loss of Smell by Improving Olfactory Function

  https://www.brainandlife.org/articles/counteract-loss-of-smell-improve-olfactory-function

  Research suggests that olfactory training could be particularly effective for people who lost their senses of smell and taste because of respiratory infections. In a study published in Rhinology in 2016, 71 percent of patients with postinfectious olfactory loss improved over one year with olfactory training, while 37 percent of patients spontaneously recovered without training over the same period. About 20 to 25 percent of people with olfactory loss related to Parkinson’s disease or trauma recover their sense of smell, per several studies.

• #1 How Can I Get My Sense of Smell back? – Southwest Ohio ENT Specialists

  https://soents.com/how-can-i-get-my-sense-of-smell-back/

  If your loss of smell (anosmia) or significant reduction in smell (hyposmia) is determined to be chronic, this may be due to direct damage to the nerves that sense smell in the nose. If after being evaluated by your ENT doctor it is determined that surgery or medicine will not improve your sense of smell, then Smell Retraining Therapy (SRT) may be an option. […] SRT sounds a little silly, but there is real research to show that it can improve your sense of smell if performed correctly. SRT was developed by Dr. Hummel, in 2009 as a way of reconnecting damaged nerve receptors in your nose to the part of the brain that processes smell. It does not work for every patient or usually restore 100% of smell. But, his studies have shown that patients who complete SRT for 12-36 weeks have significantly improved senses of smell (olfaction) compared to patients who did nothing (control). Patients who did better tended to be younger patients who began therapy sooner after losing their smell.

• #1 Relearning to smell after COVID-19 | BCM

  https://www.bcm.edu/news/relearning-to-smell-after-covid-19

  Patients are instructed to gently smell different essential oils or herbs with familiar scents for 20 seconds while focusing on their memories and experiences with that scent. […] The practice should be repeated twice a day for four to six months. […] The more you train, the better the outcome will be, Locke said. […] Sivam says that olfactory retraining requires dedicated effort, and patients should manage their expectations before starting the regimen. […] He cautions that recovering smell may not mean returning to the same level of smell as before the COVID-19 infection. […] Research into smell loss and ways to reverse it is expanding as more COVID-19 patients report this symptom. […] Sivam and Locke will discuss the research on possible treatments with their patients and make recommendations on a case-by-case basis.

• #1 How Do You Treat Parosmia or Loss of Smell? | University of Utah Health

  https://healthcare.utah.edu/the-scope/all/2022/09/how-do-you-treat-parosmia-or-loss-of-smell

  Parosmia is a condition where a persons sense of smell no longer works correctly. […] Dr. Smith, let’s start out with what is parosmia? […] So most patients will continue to slowly improve with time, which is great news given how common that this is. And what we’re seeing is that about 65% of patients will report a resolution in their abnormal or altered sense of smell by about 18 months. […] So you’re right. There are not a lot of great evidence-based therapies to treat parosmia or olfactory dysfunction. One of the ones that we do have that actually has the most amount of evidence is something called olfactory retraining. […] It can take about six to 12 weeks for patients to notice an impact, and up to 24 for them to kind of reach the maximal impact of doing that smell retraining.

• #1 Smell training is brain training, parosmia success — and five other insights from a new UAB clinic – UAB Reporter

  https://www.uab.edu/reporter/patient-care/advances/item/10005-smell-training-is-brain-training-parosmia-success-and-five-other-insights-from-a-new-uab-clinic

  Cho recommends smell training for these patients, but he has also used drug treatment specifically the anti-seizure medicine gabapentin with significant success. […] The outlook for most patients is ultimately positive. After two years, about 80 percent to 90 percent recover, Cho said. […] Research on new treatments for smell loss and the underlying causes of the problem has been turbocharged by the COVID pandemic.

• #1 First patient in UK tests new treatment for loss of sense of smell | Medical research | The Guardian

  https://www.theguardian.com/science/2025/feb/15/anosmia-smell-loss-hope-for-sufferers

  Chrissi Kelly, who says anosmia is a like a bereavement, is trialling a simple procedure that could help those who lost sense of smell during Covid or other viral infections. […] Researchers have discovered that a simple procedure can help people recover their sense of smell years after losing it to viral infections such as Covid, or even decades later. […] The first patient in the UK began receiving treatment this month and doctors hope the process could be easily rolled out across the NHS. […] Chrissi Kelly is the first patient in the UK to receive the treatment, which consists of injections of platelet-rich plasma (PRP) from her own blood, prepared by using a centrifuge to separate the platelets from red and white blood cells. […] But the pandemic also sparked a new wave of research. Prof Zara Patel, director of endoscopic skull base surgery at Stanford University, had been examining anosmia for some time and spotted a neurology paper that suggested PRP might help regenerate nerves.

• #1 Loss of Smell: Current & Emerging Therapies

  https://www.backtable.com/shows/ent/articles/loss-of-smell-current-emerging-therapies

  Apart from high-dose omega-3 fatty acids, no nutritional supplements produce convincing evidence in treatment of smell loss. […] High-dose omega-3 fatty acid supplements reduced rates of smell loss in a randomized controlled trial of patients undergoing endoscopic skull base surgery. […] Platelet-rich plasma (PRP) shows promise in stimulating smell recovery amongst patients with post-viral smell loss. Injected into the olfactory cleft, platelet-rich plasma contains growth factors from the patients own blood plasma that stimulate regrowth of olfactory neurons. […] A randomized controlled trial run by Dr. Patel demonstrated that patients with COVID-19 smell loss were twelve times as likely to recover olfactory abilities when treated with PRP versus a placebo injection.

• #1 Nasal injections could treat long-term COVID-19-related smell loss | News Center

  https://med.stanford.edu/news/all-news/2023/01/covid-smell-loss-treatment.html

  In a trial led by Stanford Medicine researchers, more than half of patients with persistent smell loss saw improvement with injections of platelet-rich plasma. […] Now Patel’s team has tested a new treatment for long-term, COVID-19-related smell loss using injections of platelet-rich plasma derived from a patient’s own blood. […] The study was published Dec. 12 in the International Forum of Allergy and Rhinology. […] Half the participants received platelet-rich plasma injections into the tissue deep inside their nasal cavity every two weeks for six weeks, while the other half received placebo injections (of saline) on the same schedule. […] At three months, 57.1% of the platelet-rich plasma group had shown a clinically significant improvement, compared with just 8.3% in the placebo group. […] Patel is now offering platelet-rich plasma injections to patients outside the trial. […] „But the sooner you perform some sort of definitive intervention, probably the better chance you have of improvement.”

• #1 First patient in UK tests new treatment for loss of sense of smell | Medical research | The Guardian

  https://www.theguardian.com/science/2025/feb/15/anosmia-smell-loss-hope-for-sufferers

  So if PRP could help the olfactory nerve regenerate, it might relieve anosmia. […] Patel set up a series of randomised control trials easier to recruit after Covid and found that PRP worked better than a placebo after three months and the effect was greater after 12 months. […] [The evidence] is significant to a point that I feel I should be offering this to my patients, and it is a relatively minimally invasive procedure. […] PRP is used within the NHS for other things, so Im hopeful we will be able to offer it. […] Kelly needs to have two further PRP injections over the next three months to complete the treatment.

• #1 When Loss of Smell and Taste Occurs with Long COVID > News > Yale Medicine

  https://www.yalemedicine.org/news/when-loss-of-smell-and-taste-occurs-with-long-covid

  Injection of an anesthetic into this tiny nerve bundle has been used for many years to address different forms of nerve pain. More recently, it has been looked at as a way to treat loss of smell and taste. […] Most of medical literature on SGB for loss of smell or taste in patients with Long COVID is limited to case studies. […] When I recently told Patricia about SGB as a possible treatment for her loss of smell and taste, I explained how little we really know about its effectiveness. […] Even so, she says she feels hopeful that the SGB will return my ability to enjoy life to its fullest.

• #1 SGB Treatment to Help Recover Loss of Taste and Smell from COVIDAccessibility ToolsIncrease TextDecrease TextGrayscaleHigh ContrastNegative ContrastLight BackgroundLinks UnderlineReadable FontResetSitemapHelpFeedback

  https://painandspinespecialists.com/sgb-treatment-to-help-recover-loss-of-taste-and-smell-from-covid/

  Yet, because of its ability to target the sympathetic nervous system, SGB treatment has been found to provide effective restoration of a loss of smell and taste due to COVID-19 as well as reduce parosmia symptoms from COVID-19. […] If you are struggling with a loss of taste and smell or have parosmia from COVID, consider an SGB treatment. […] Therefore, SGB treatment can help block part of the sympathetic nervous system within the head and neck that may be experiencing increased activity due to COVID. […] However, if you notice you are experiencing long-term loss of taste and smell, treatment for Long COVID is essential. […] Our stellate ganglion block injections can help you recover from these long COVID symptoms for good, so you can live a normal, healthy life.

• #1

  https://appellation.co/blogs/journal/still-suffering-with-anosmia-what-to-do-if-you-still-cant-smell-anything?srsltid=AfmBOopiCneKGAAq_F_Wv6wlyx7rR5ClBBdhjdQnbNvZQFNEUfYNqmnH

  Though not included in IFM’s list, Vitamin A nasal drops were researched as a potential treatment for smell loss at the University of East Anglia in the UK. […] A recent Stanford Medicine-led study found that post-viral smell loss improved when patients were given injections platelet-rich plasma injections in their nasal tissue. […] Recovery Is A Long Road […] While the majority of post-viral patients will have their sense of smell restored, the road to recovery is long.

• #1 How Do You Treat Parosmia or Loss of Smell? | University of Utah Health

  https://healthcare.utah.edu/the-scope/all/2022/09/how-do-you-treat-parosmia-or-loss-of-smell

  The common ones that we’re hearing about right now are things like Alpha-lipoic acid, which I know has been really popular on TikTok for a while. […] There is some evidence that using these therapies can potentially improve your sense of smell. […] The most effective thing that you can do right now, if you’re struggling from parosmia, is actually lifestyle modifications. […] I think it’s an important part of my job to see patients who have parosmia after experiencing this alteration of their sense of smell so that we can, number one, take a good look in the nose, rule out those other things that we talked about earlier that could potentially be causing an alteration in the sense of smell for your good overall health. […] Having a chance to talk about that, to validate what they’re experiencing, to tell people, „Look, you’re not crazy. This isn’t in your head. This is a real thing,” I actually think that’s really important to do.

• #1

  https://pccarx.com/Blog/post-covid-loss-of-smell-3-possible-treatment-options

  Another possible treatment option is intranasal vitamin A. […] A third possible treatment option is theophylline. […] The literature gives three options as possible therapies for patients experiencing post-COVID hyposmia or anosmia: olfactory training, intranasal vitamin A or intranasal theophylline.

• #1 Regaining your sense of taste and smell after COVID-19 | HealthPartners Blog

  https://www.healthpartners.com/blog/how-to-regain-sense-of-smell-and-taste-after-covid-19/

  It may take a long time to start noticing improvements in your taste and smell. But having the support of a doctor or clinician to explain long haul COVID treatment can make the process easier. […] When you work with an occupational therapist, youll get exercises, education and personalized instruction to help you regain or fix your sense of smell. […] Alternative treatments may also be an option. For example, acupuncture may help get you smelling again.

• #1 Coping with the loss of smell and taste – Harvard Health

  https://www.health.harvard.edu/blog/coping-with-the-loss-of-sense-of-smell-and-taste-2020101921141

  If you suffer from olfactory loss, don’t be discouraged if some of the essences smell different from what you expected: distortions associated with the loss of smell (troposmia) are not uncommon. […] When eating, if you cannot taste the full range of flavors of a dish, pay attention to the basic ones sweet, bitter, sour, salty, or umami as well as to the food’s texture and the sensation on your palate. This will help you focus on what you still can taste, rather than on what you cannot. […] In my practice with patients with post-COVID losses, and in my own recovery, I have found the following coping strategies helpful. […] Consult with an ear, nose, and throat specialist for guidance. […] For additional help, see a counselor or join a support group.

• #1 Loss of Smell & Taste Causes & Treatment for Arizona— Valley ENT

  https://www.azvent.com/conditions/nose/smell-taste-disturbance/

  T treating the underlying cause of your loss of smell is often the first step. For example, managing chronic conditions like sinusitis or allergies can help restore normal function. […] Other treatments include: […] Medications: Corticosteroids can reduce inflammation in the nasal passages, improving airflow and smell. Your physician may also prescribe antihistamines and decongestants to alleviate symptoms. […] Lifestyle changes: Maintaining good oral hygiene, quitting smoking, and using aromatic herbs and spices in cooking can improve your sense of smell and taste. […] Surgery: Nasal obstructions like polyps or a deviated septum may require surgical removal. Procedures such as endoscopic sinus surgery can help clear the nasal passages and restore the sense of smell. […] If your sense of smell and taste remains affected, counseling can provide support and coping strategies. […] Consulting with an otolaryngologist (ENT specialist) is essential for accurate diagnosis and personalized treatment planning. By addressing underlying issues and following a tailored treatment plan, individuals may restore their sense of smell and taste and improve their overall quality of life.

• #1 Treatment for Decreased Sense of Smell and Smell loss

  https://www.dryagoda.com/ent-medicine/ent-nose/decreased-sense-smell/

  Luckily, the olfactory system has the capacity to regenerate. Dr. Yagoda recommends “smell training” for all patients with anosmia. This significantly amplifies (and often doubles) the rate of recovery. Guided olfactory training is a deliberate, active, contemplative smelling process used to support the regeneration of olfactory neurons, forge new neural pathways and reinforce existing ones. […] If you are suffering from loss of smell Dr. Yagoda can connect you with Ms. Holzel for one-on-one counseling.

• #1 Anosmia: Symptoms, Causes, and Treatments

  https://www.webmd.com/brain/anosmia-loss-of-smell

  Sometimes a person will regain their sense of smell spontaneously. Unfortunately, anosmia is not always treatable, especially if age is the cause. But there are steps you can take to make living with the inability to smell more pleasant and safer. For example, put fire detectors and smoke alarms in your home and office and take extra care with leftovers. If you have any doubt about a food’s safety, don’t eat it. […] If you smoke, quit. Smoking can dull your senses, including your sense of smell.

• #1 Anosmia (loss of smell) | healthdirect

  https://www.healthdirect.gov.au/anosmia-loss-of-smell

  Anosmia is the medical term for the loss of smell. […] Loss of smell can be caused by many things, such as injury and COVID-19. […] If you have anosmia, and you experience a loss of appetite or depression, talk to your doctor. […] Treatment depends on why you lost your sense of smell. It can involve: steroid medication, antihistamines, antibiotics, surgery. […] If you have anosmia, you may find that food tastes bland. This can affect your life, particularly if your family and social life revolves around meals. This can impact your appetite. […] If you do have anosmia, you can make your home safer by: reading food expiry dates carefully, making sure your smoke alarms are working, checking that cookers, barbecues and electrical appliances are turned off properly. […] If you have a cold, your sense of smell will usually come back within 1 or 2 weeks. See your doctor if your sense of smell doesn’t come back after this time.

• #1 What Causes You to Lose Your Sense of Taste or Smell? | K Health App

  https://khealth.com/learn/symptom/lost-taste-smell-anosmia/

  Try new cuisines: Experiment with different cuisine styles, especially those that have traditionally strong flavors, such as Indian or Mexican cuisines. […] Eat hot foods: The temperature of food can affect our sense of taste. Studies have found that the hotter food is, the more intensely our taste buds react. When possible, heat your meals instead of eating them cold or at room temperature. […] Look for textures: Texture contributes to our enjoyment of food, so try different foods that are crispy, crunchy, or smooth, as this may engage your senses in fresh ways. […] Watch your salt and sugar intake: If you suffer from hyposmia and hypogeusia, you may be drawn to foods high in salt or sugar, as these flavors are often easier to taste. Be mindful not to overdo it with sweet or salty foods in your diet.

• #1 Healthy aging

  https://www.mayoclinic.org/healthy-lifestyle/healthy-aging/expert-answers/loss-of-taste-and-smell/faq-20058455

  If your symptoms don’t improve after treating the cause of your loss of taste and smell, your health care provider may recommend smell training therapy. This therapy involves smelling four different scents for about 10 to 20 seconds twice a day for at least three months. Your health care provider might also recommend strategies to help you cope with loss of taste and smell. […] If necessary, your health care provider might recommend consulting an allergist, an ear, nose and throat specialist (otolaryngologist), a neurologist, or other specialist.

• #1 Cancer Treatment Loss of Taste and Smell

  https://www.cancercenter.com/integrative-care/taste-and-smell-changes

  Seek out nutritional support: If youre losing weight from not eating, developing a nutrient deficiency or just needing more personalized advice, consult with an oncology dietitian at your cancer center or hospital. He or she may work with you to develop an eating plan thats right for you, safeguard against malnutrition, and help you live well during and after your cancer treatment.

• #1 How to Smell Again After COVID-19: 6 Steps to Take

  https://www.verywellhealth.com/how-to-smell-again-after-covid-8547575

  Some medications that reduce inflammation in your nasal passages may help restore some of your sense of smell. One study showed that glucocorticoids (steroid medications) like Nasacort Allergy 24HR (triamcinolone) and Flonase (fluticasone) nasal spray help significantly improve the sense of smell for people recovering from COVID-19. Some study participants reported a restored sense of smell within a week. […] Nasal hygiene is another method that may help you restore your sense of smell. Often recommended as part of the treatment strategy for allergies and other forms of nasal irritation, daily nasal lavageor rinsingwith saline or an added steroid may offer relief. […] More research is needed to determine the best way to treat anosmia related to COVID-19. However, if you notice a loss of smell after COVID-19, schedule an appointment with a healthcare provider to ensure no underlying problems contribute to your loss of smell.

• #1 Lost or Changed Sense of Smell: Causes & Treatment – ENT LDN

  https://entlondon.org.uk/blogs/lost-or-changed-sense-of-smell-causes-and-treatment/

  4. Avoid Triggers […] Specific allergy triggers or other dust factors can change the sense of smell. The first step should be to diagnose these triggers via allergy tests to identify particular factors for treatment. Smoking is a significant contributor to nasal problems. If you are suffering from impaired smell, it is vital to quit smoking and adopt a healthy lifestyle to prevent nasal abnormalities. […] 5. Medication Treatment […] The doctor can prescribe medications to promote a healthy recovery. These include antibiotics to treat sinus infections, allergies, or inflammation. If a patient is allergic to certain ingredients, the doctor can suggest alternative medicines to treat the nasal infection without affecting other conditions. […] The good news is that many causes of smell loss are treatable. Medications, injuries, or even exposure to chemicals might be the reason. Once the doctor identifies the cause, they can recommend the best action to get your health back on track.

• #1 Lost or changed sense of smell

  https://www2.hse.ie/conditions/lost-or-changed-sense-of-smell/

  A change in your sense of smell can be unpleasant and affect how things taste. But it is not usually serious and may get better in a few weeks or months. […] If your sense of smell is affected by an infection or allergy, rinsing the inside of your nose may help. Rinse up to 3 times a day with a salt water solution. […] Your sense of smell may go back to normal in a few weeks or months. […] Treating the cause might help. For example, steroid nasal sprays or drops might help if you have sinusitis or nasal polyps. […] A treatment called smell training can also help some people. […] Sometimes changes in sense of smell cannot be treated and may be permanent.

• #1 Loss of smell

  https://www.ion.ac.uk/news/how-to-regain-your-sense-of-smell

  Covid-19 caused millions to lose their sense of smell, long after contracting the disease. […] The odds of a full recovery are good, however, with one study reporting that 75-80% of people had regained their taste and smell at two months after infection, and 95% had done so at the six month mark. […] UK charity AbScent, which funds research that supports those experiencing smell loss, has seen its community grow from 1,500 members pre-pandemic to more than 76,000: all of whom are seeking advice and support. […] Founder Chris Kelly told Optimum Nutrition: Loss of smell can have profound effects on quality of life. […] Smell training may stimulate the turnover of specialised nerve cells to help restore smell function, and boost cognitive processing of the incomplete sensory information in those with parosmia.

• #1 A Change in Smell After COVID-19 Infection: What You Need to Know | University of Utah Health

  https://healthcare.utah.edu/healthfeed/2022/09/change-smell-after-covid-19-infection-what-you-need-know

  Some people experience a change to their taste and smell following COVID-19 infection, also known as parosmia (abnormal sense of smell), hyposmia (decreased sense of smell), and anosmia (loss of sense of smell). […] Patients usually improve slowly with time. About 65 percent of people with COVID-19-induced parosmia or hyposmia regain these senses by about 18 months, while 80-90 percent regain these senses by two years. […] There are no guaranteed treatments for post-COVID-19 parosmia. However, some therapies may help some patients. These include: Olfactory retraining is the process of retraining your nose to smell. It involves smelling strong scents (citrus, cloves, eucalyptus) every day while thinking about what they smell like to try to help reform normal responses to your nose and brain. Research has shown it can improve parosmia in long COVID patients.

• #1 Ways to regain your sense of smell – Harvard Health

  https://www.health.harvard.edu/diseases-and-conditions/ways-to-regain-your-sense-of-smell

  Sniffing peanut butter, peppermint, and other strong scents may help you retrain your brain and restore your sense of smell. […] When it occurs, you need to try to regain the sense as soon as possible. „The longer you go without it, the less likely you are to recover it,” says Dr. Neil Bhattacharyya, an ear, nose, and throat specialist (otolaryngologist) at Harvard-affiliated Massachusetts Eye and Ear. […] If you’ve lost your sense of smell, don’t wait around for it to come back. „We used to tell people to wait six months before they came to see us about it,” Dr. Bhattacharyya says. „But now we want you to begin smell retraining therapy as soon as possible to activate the body’s recovery process.” […] Smell retraining therapy is simply a matter of sniffing a wide variety of odor-generating elements.

• #1 Relearning to smell after COVID-19 | BCM

  https://www.bcm.edu/news/relearning-to-smell-after-covid-19

  But they say its important to consult with your doctor before trying anything. […] If you have no smell for two weeks, its important to come in and get checked out, Locke said. […] Either way, I think having a doctor evaluate the condition is important to avoid self-treatment resulting in a delay in diagnosis.

• #1 How to Get Your Taste Buds Back: 18 Causes, What to Do Next

  https://www.healthline.com/health/how-to-get-your-taste-buds-back

  Consult with a healthcare professional about loss of taste and any other symptoms you may have. Determining and treating the cause may help you regain your taste. […] Talk with a doctor if loss of taste goes well beyond a recent bout of congestion or illness, has come on suddenly, or is accompanied by other symptoms. […] Treating the underlying cause can often help get your taste buds back on track.

• #1 Anosmia Smell Loss Treatment Houston TX | Hyposmia Houston

  https://houstonadvancedsinus.com/rhinologic-conditions/anosmia-smell-loss/

  If Dr. Kuperan determines that you have a nasal obstruction, such as nasal polyps, he will recommend a course of treatment to address that. […] In rare cases of neural smell loss caused by skull base or sinus tumors, Dr. Kuperan will recommend advanced endoscopic sinus surgery or anterior skull base tumor resection. […] If you are struggling with smell loss, we can help. The sooner you get treatment, the more likely you are to regain your sense or smell.

• #2 What’s Causing My Loss of Smell and Taste?

  https://www.webmd.com/brain/ss/slideshow-causes-of-loss-of-smell-and-taste

  Certain kinds of cancer and treatment can change the messages between your nose, mouth, and brain. This includes tumors in your head or neck and radiation to those areas. Chemotherapy or targeted therapy and some medications for side effects can also have an effect. You may have a metallic taste in your mouth or find that certain odors are different or stronger. These issues often go away when your treatment ends. […] If you cant taste or smell after a few days, talk to your doctor to rule out other conditions. […] Both are treated with nasal sprays, medication, or surgery.

• #2 Anosmia – Wikipedia

  https://en.wikipedia.org/wiki/Anosmia

  Anosmia may be temporary or permanent. […] While acquired anosmia may have potential treatments depending on the underlying cause, such as medications or surgery, congenital anosmia currently has no known cure, and management focuses on safety precautions and coping strategies. […] When anosmia is caused by inflammatory changes in the nasal passageways, it is treated simply by reducing inflammation. […] Though anosmia caused by brain damage cannot be treated, anosmia caused by inflammatory changes in the mucosa may be treated with glucocorticoids. Reduction of inflammation through the use of oral glucocorticoids such as prednisone, followed by long term topical glucocorticoid nasal spray, would easily and safely treat the anosmia. […] Anosmia caused by a nasal polyp may be treated by steroidal treatment or removal of the polyp. […] Although very early in development, gene therapy has restored a sense of smell in mice with congenital anosmia when caused by ciliopathy.

• #2 Anosmia (loss of smell) | healthdirect

  https://www.healthdirect.gov.au/anosmia-loss-of-smell

  Anosmia is the medical term for the loss of smell. […] Loss of smell can be caused by many things, such as injury and COVID-19. […] If you have anosmia, and you experience a loss of appetite or depression, talk to your doctor. […] Treatment depends on why you lost your sense of smell. It can involve: steroid medication, antihistamines, antibiotics, surgery. […] If you have anosmia, you may find that food tastes bland. This can affect your life, particularly if your family and social life revolves around meals. This can impact your appetite. […] If you do have anosmia, you can make your home safer by: reading food expiry dates carefully, making sure your smoke alarms are working, checking that cookers, barbecues and electrical appliances are turned off properly. […] If you have a cold, your sense of smell will usually come back within 1 or 2 weeks. See your doctor if your sense of smell doesn’t come back after this time.

• #2 Relearning to smell after COVID-19 | BCM

  https://www.bcm.edu/news/relearning-to-smell-after-covid-19

  But they say its important to consult with your doctor before trying anything. […] If you have no smell for two weeks, its important to come in and get checked out, Locke said. […] Either way, I think having a doctor evaluate the condition is important to avoid self-treatment resulting in a delay in diagnosis.

• #2 How to Smell Again After COVID-19: 6 Steps to Take

  https://www.verywellhealth.com/how-to-smell-again-after-covid-8547575

  Some medications that reduce inflammation in your nasal passages may help restore some of your sense of smell. One study showed that glucocorticoids (steroid medications) like Nasacort Allergy 24HR (triamcinolone) and Flonase (fluticasone) nasal spray help significantly improve the sense of smell for people recovering from COVID-19. Some study participants reported a restored sense of smell within a week. […] Nasal hygiene is another method that may help you restore your sense of smell. Often recommended as part of the treatment strategy for allergies and other forms of nasal irritation, daily nasal lavageor rinsingwith saline or an added steroid may offer relief. […] More research is needed to determine the best way to treat anosmia related to COVID-19. However, if you notice a loss of smell after COVID-19, schedule an appointment with a healthcare provider to ensure no underlying problems contribute to your loss of smell.

• #2

  https://www.nasoneb.com/blogs/healthtalk/how-to-get-your-taste-buds-back?srsltid=AfmBOoo02RUXkq67oh1JShkoNE7jezG7HneLWxLYezc2J5pyOnKjIwZ1

  In many cases, the loss of a persons sense of smell and taste is actually a symptom of an underlying cause, such as an upper respiratory infection (URI) or sinusitis from a cold or allergies, and usually clears up as the primary condition subsides. […] Staying hydrated and getting plenty of rest are both good ways to help power your immune system, reduce inflammation and swelling, and dilute excessive mucus build-up caused by an upper respiratory or sinus infection. […] Use a nasal nebulizer to deliver a low-volume, highly concentrated mist intranasally to help open your sinuses and reduce mucus build-up. […] Allergies and sinus infections are often treated with over-the-counter decongestants and antihistamines to reduce post nasal drip, nasal congestion, and excessive mucus build-up. These types of treatments can help you regain your sense of smell and taste by temporarily reducing the amount of congestion blocking your smell sensors, located high inside the back of your nose.

• #2 Lost or changed sense of smell

  https://www2.hse.ie/conditions/lost-or-changed-sense-of-smell/

  A change in your sense of smell can be unpleasant and affect how things taste. But it is not usually serious and may get better in a few weeks or months. […] If your sense of smell is affected by an infection or allergy, rinsing the inside of your nose may help. Rinse up to 3 times a day with a salt water solution. […] Your sense of smell may go back to normal in a few weeks or months. […] Treating the cause might help. For example, steroid nasal sprays or drops might help if you have sinusitis or nasal polyps. […] A treatment called smell training can also help some people. […] Sometimes changes in sense of smell cannot be treated and may be permanent.

• #2 Treatments | Stanford Health Care

  https://stanfordhealthcare.org/medical-conditions/ear-nose-and-throat/anosmia-loss-of-smell/treatments.html

  […] […] Surgery […] If you have a tumor, nasal polyp, deviated septum, or other obstruction thats causing smelling abnormalities, your doctor may recommend surgery. Our renowned team of head and neck surgeons has experience with a range of techniques for nasal surgery. […] We are skilled at the latest minimally invasive options, such as endoscopic sinus surgery and endoscopic endonasal surgical techniques. We perform these procedures using a thin, flexible tube inserted through the nose, so theres no need for incisions. Your care team will recommend the appropriate procedure and deliver customized care.

• #2 How to Counteract Loss of Smell by Improving Olfactory Function

  https://www.brainandlife.org/articles/counteract-loss-of-smell-improve-olfactory-function

  Losing the sense of smell can be difficult and frustrating, says neuroscientist Richard Doty, PhD, FAAN, who directs the Smell and Taste Center at the Perelman School of Medicine at the University of Pennsylvania. […] Treatment for smell loss depends on the cause. For example, many drugs, including certain antibiotics, antihistamines, antihypertensives, and diabetes therapies, can interfere with the ability to smell. The solution can be as simple as changing the prescription. […] A therapy known as olfactory training involves repeatedly sniffing specific scents while looking at a picture related to each scent to help stimulate the olfactory system and establish a memory of that smell. Jentz recently started olfactory training herself after her doctor recommended it. These scents are strong enough that I actually can still smell them, and it’s kind of pleasant, she says.

• #2 Olfactory Training – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK567741/

  Olfactory training is a non-pharmacological and non-surgical treatment option for patients with olfactory dysfunction. Patients undergoing olfactory training expose themselves to 4 different odors twice daily for at least 24 weeks. […] A non-surgical and non-pharmacological approach to improve olfactory function is olfactory training, wherein patients expose themselves twice daily to different odors over the course of several months. […] Several studies have described the efficacy of olfactory training. […] Olfactory training is comparatively simple, and so far, serious side effects have not been reported. […] Olfactory training is the only treatment option available to patients with olfactory dysfunction due to other etiologies. For this reason, olfactory training is particularly important for the management of patients with olfactory decline.

• #2 Ways to regain your sense of smell – Harvard Health

  https://www.health.harvard.edu/diseases-and-conditions/ways-to-regain-your-sense-of-smell

  Sniffing peanut butter, peppermint, and other strong scents may help you retrain your brain and restore your sense of smell. […] When it occurs, you need to try to regain the sense as soon as possible. „The longer you go without it, the less likely you are to recover it,” says Dr. Neil Bhattacharyya, an ear, nose, and throat specialist (otolaryngologist) at Harvard-affiliated Massachusetts Eye and Ear. […] If you’ve lost your sense of smell, don’t wait around for it to come back. „We used to tell people to wait six months before they came to see us about it,” Dr. Bhattacharyya says. „But now we want you to begin smell retraining therapy as soon as possible to activate the body’s recovery process.” […] Smell retraining therapy is simply a matter of sniffing a wide variety of odor-generating elements.

• #2 Reddit – The heart of the internet

  https://www.reddit.com/r/fragrance/comments/sxyjlx/scent_physical_therapy_for_people_who_lost_sense/

  My story: I lost all sense of smell for over six months after a bad cold. […] Smell training: Researchers are now recommending „smell training” instead of steroids to help the brain regain the sense of smell. It’s free and easy to do. […] This involves sniffing four things that have a distinctive, easily identifiable and familiar smell – for example, oranges, mint, garlic or coffee – twice a day for several months. […] If it doesn’t return, he says „smell training” helps to retrain the brain’s smell pathways to recognise different odours. […] „It aims to help recovery based on neuroplasticity – the brain’s ability to reorganise itself to compensate for a change or injury,” he said.

• #2 Treatments | Stanford Health Care

  https://stanfordhealthcare.org/medical-conditions/ear-nose-and-throat/anosmia-loss-of-smell/treatments.html

  […] […] Smell Retraining Therapy (SRT) […] Depending on your health, age, and the cause of anosmia, your doctor may recommend SRT. Also called olfactory training, this therapy involves smelling different scents at scheduled times throughout the day over several months. Usually, the therapy includes a floral scent; a spicy scent, such as cloves; and a fruity scent, such as lemon. You take about 20 seconds to focus on each smell. SRT exercises your olfactory system and creates new pathways between olfactory nerves (those related to the sense of smell) and the brain. It can help improve smell loss from multiple different causes. […] At Stanford Health Care, our team pioneered a treatment that combines SRT with steroid nasal rinses. These rinses improved outcomes for people undergoing SRT.

• #2 How Do You Treat Parosmia or Loss of Smell? | University of Utah Health

  https://healthcare.utah.edu/the-scope/all/2022/09/how-do-you-treat-parosmia-or-loss-of-smell

  Parosmia is a condition where a persons sense of smell no longer works correctly. […] Dr. Smith, let’s start out with what is parosmia? […] So most patients will continue to slowly improve with time, which is great news given how common that this is. And what we’re seeing is that about 65% of patients will report a resolution in their abnormal or altered sense of smell by about 18 months. […] So you’re right. There are not a lot of great evidence-based therapies to treat parosmia or olfactory dysfunction. One of the ones that we do have that actually has the most amount of evidence is something called olfactory retraining. […] It can take about six to 12 weeks for patients to notice an impact, and up to 24 for them to kind of reach the maximal impact of doing that smell retraining.

• #2 Smell retraining therapy and long COVID | My Doctor Online

  https://mydoctor.kaiserpermanente.org/covid-19/smell-retraining-therapy-and-long-covid

  You can use smell retraining therapy (SRT) if you have loss of sense of smell due to long COVID. […] Most people with long COVID gradually regain their sense of smell, though this can take months or even longer. […] You can use SRT at home (also called olfactory training). Studies show SRT is generally effective, though results vary from person to person. […] SRT works by strengthening the nerves involved in our sense of smell. […] Some people also lose their sense of taste. SRT can help you recover this sense, as well. […] Start with 4 scents. These 4 work well for most people: rose, eucalyptus, lemon, and clove. […] After 3 months, switch to 4 new scents. Use them with the same twice-daily method. Suggestions: menthol, thyme, tangerine, and jasmine. […] After 3 more months (6 months after starting SRT), again switch to 4 new scents. Suggestions: green tea, bergamot, rosemary, and gardenia.

• #2 Post-Covid, Many Patients Try Smell Therapy. But Does it Work?

  https://undark.org/2021/04/20/post-covid-many-patients-try-smell-therapy-but-does-it-work/

  Sowerby says he has seen smell therapy take patients from having no sense of smell to having a little. […] The original smell training technique includes only four odors, but according to Sowerby, adding additional scents can improve the approach’s effectiveness — as can training over a longer period of time. […] In 2015, Hummel proposed a modified smell training regimen with a wider range of odors including menthol, thyme, tangerine, jasmine, green tea, rosemary, bergamot, and gardenia. […] But even these modest claims of benefits related to smell training have detractors. […] Moein notes that smell training “might have some effect for some people” but it likely depends upon the reason why the smell loss has occurred. […] For his part, Hummel acknowledges that most people with post-viral anosmia will recover without training, and that smell therapy might not be appropriate for everyone.

• #2 Nasal injections could treat long-term COVID-19-related smell loss | News Center

  https://med.stanford.edu/news/all-news/2023/01/covid-smell-loss-treatment.html

  In a trial led by Stanford Medicine researchers, more than half of patients with persistent smell loss saw improvement with injections of platelet-rich plasma. […] Now Patel’s team has tested a new treatment for long-term, COVID-19-related smell loss using injections of platelet-rich plasma derived from a patient’s own blood. […] The study was published Dec. 12 in the International Forum of Allergy and Rhinology. […] Half the participants received platelet-rich plasma injections into the tissue deep inside their nasal cavity every two weeks for six weeks, while the other half received placebo injections (of saline) on the same schedule. […] At three months, 57.1% of the platelet-rich plasma group had shown a clinically significant improvement, compared with just 8.3% in the placebo group. […] Patel is now offering platelet-rich plasma injections to patients outside the trial. […] „But the sooner you perform some sort of definitive intervention, probably the better chance you have of improvement.”

• #2 Hope for restoring lost sense of smell

  https://www.mediclinic.co.za/en/foh-corporate/innovation/promising-smell-restoration-treatment.html

  What was quite clear is that most of the plasma patients received significant clinical benefits either in partially improving or fully restoring their sense of smell, says Dr Goncalves. […] The treatment needs to be done after six months and within the first year of losing your sense of smell, as after 14 months there is usually permanent nerve damage and the longer you have a loss of smell, the less likely you will regain it, says Dr Goncalves. […] If the treatment proves to have been effective after three months, this should be a lifelong benefit, says Dr Goncalves.

• #2 SGB Treatment to Help Recover Loss of Taste and Smell from COVIDAccessibility ToolsIncrease TextDecrease TextGrayscaleHigh ContrastNegative ContrastLight BackgroundLinks UnderlineReadable FontResetSitemapHelpFeedback

  https://painandspinespecialists.com/sgb-treatment-to-help-recover-loss-of-taste-and-smell-from-covid/

  One of the most common symptoms of COVID-19 is a loss of taste and/or smell. […] Nearly 5% of confirmed COVID cases report suffering from this loss of smell and taste, even after COVID recovery. […] However, stellate ganglion block (SGB) treatment provides those suffering from loss of taste and smell from COVID the chance to recover their senses to get back to living a normal life. […] Various promising long COVID treatments, like SGB treatment, show mounting positive evidence that supports this treatment can help regain your loss of taste and smell from COVID. […] Olfactory retraining provides a potential solution to regain your loss of taste and smell following COVID. […] SGB (stellate ganglion block) treatment provides an effective solution for people who either suffer from parosmia or a general loss of taste or smell as part of lingering long COVID symptoms.

• #2 10-minute procedure may repair distorted sense of smell in COVID survivors | CIDRAP

  https://www.cidrap.umn.edu/covid-19/10-minute-procedure-may-repair-distorted-sense-smell-covid-survivors

  A new minimally invasive procedure may restore COVID-related impaired sense of smell, suggests a small study to be presented at next week’s Radiological Society of North America (RSNA) annual meeting in Chicago. […] SGB shows promise for patients with long term post-COVID parosmia, and CT provides ideal efficiency and guidance. […] „Other treatments have failed to date,” he said. „This injection is working.”

• #2 Restoring Smell and Taste After Covid

  https://research.jefferson.edu/2023-magazine/restoring-smell-and-taste-after-covid.html

  Since inflammation can contribute to disrupted smell, steroids in the form of nasal sprays or rinses are also prescribed. […] There have also been some early experiments with intranasal vitamin A, which has been shown to be beneficial in other forms of smell loss. […] But these treatments dont have robust science behind them, says Dr. Rosen. […] This is where platelet-rich plasma comes in. […] The silver lining to this very dark cloud is that weve never had such a large cohort of anosmia patients at one time, and we can pinpoint the exact cause, says Dr. Dalton. […] Dr. Rosen and his team began developing a topical method, using dissolvable sponges saturated with PRP. […] The results of their pilot trial are promising. Among those who completed a three-month course of PRP treatments, 60% experienced improvements.

• #2 Anyone Gotten their Taste and Smell Back after Covid in 2022? | Mayo Clinic Connect

  https://connect.mayoclinic.org/discussion/loss-of-taste-and-smell-after-covid-in-2022/

  I recommend you look at the free membership ‘Abscent’ website with huge range of tips, discussions, personal reflections, on line courses etc. I have tried the Italian research of the supplement Glialia (very finely ground um PEA-LUT) designed to pass the brain barrier, with a protocol of Alpha Lipoic Acid and smell training.

• #2

  https://appellation.co/blogs/journal/still-suffering-with-anosmia-what-to-do-if-you-still-cant-smell-anything?srsltid=AfmBOopiCneKGAAq_F_Wv6wlyx7rR5ClBBdhjdQnbNvZQFNEUfYNqmnH

  Olfactory therapy, or smell training, is a bit like rehabilitation or physiotherapy for your nose. […] Repeatedly smelling these different scents multiple times each day appears to restore neural connections disrupted by the virus, retraining, or reawakening, the essential communication pathways that enable us to smell. […] In just one study on post-viral patients at European hospitals, 95 percent were able to recover their sense of smell within six months. […] Aside from olfactory training, there’s currently no clinically endorsed therapy for smell loss. […] Acupuncture has also shown promising results for many patients with inflammation and olfactory dysfunction, while the Institute for Functional Medicine (IFM) lists some helpful advice and evidence-backed supplements and lifestyle-based interventions to boost mitochondrial health, which is impaired in those with long Covid.

• #2 Anosmia FAQ – Monell Chemical Senses Center

  https://monell.org/anosmia-faq/

  If you notice a problem with your sense of smell, you should first consult an otolaryngologist (ear, nose and throat specialist), preferably one who sub-specializes in nasal-sinus disease (as opposed to head-neck cancer or auditory problems). […] Anosmia has long endured the dual challenge of being an invisible disability that involves our least-understood sensory system: smell. In the past few years, however, there has been a surge of interest about anosmia, with groups such as the Monell Center in the US and Fifth Sense in the UK working to raise awareness about the incidence and consequences of anosmia. […] Targeted research at Monell, made possible through government grants and contributions from individuals, is focusing on understanding the underlying causes of anosmia to identify potential treatments.

• #2 What Causes You to Lose Your Sense of Taste or Smell? | K Health App

  https://khealth.com/learn/symptom/lost-taste-smell-anosmia/

  The primary approach to treating loss of taste and smell is to treat the underlying cause of the issue. There is no direct cure for anosmia and ageusia, though in most cases, treating the cause will return all or part of your sense of smell and taste. […] A stuffy or runny nose due to allergies or a viral infection (such as cold and flu) can be treated with over-the-counter medications including decongestants, antihistamines, or steroids to ease inflammation. Easing the stuffiness may help increase your sense of taste and smell in the short term. […] If hyposmia or hypogeusia is the result of aging, a chronic condition, brain trauma, or another cause that permanently alters the senses, there is no treatment to fully regain these senses. In these cases, patients are encouraged to: […] Add more seasonings: Season your food with herbs, spices, vinegar, hot sauce, or other flavorings. Be open to trying new sauces and condimentsif your sense of taste has changed, you may enjoy flavors you didnt before.

• #2 Healthy aging

  https://www.mayoclinic.org/healthy-lifestyle/healthy-aging/expert-answers/loss-of-taste-and-smell/faq-20058455

  Some loss of taste and smell is natural with aging, especially after age 60. […] Loss of taste and smell can have a significant impact on quality of life. It often leads to decreased appetite and poor nutrition. It can sometimes contribute to depression. Loss of taste and smell also might tempt you to use excess salt or sugar on your food to enhance the taste. This could be a problem if you have high blood pressure or diabetes. […] If you’re experiencing loss of taste and smell, see your health care provider. Some causes of impaired taste and smell are treatable. For example, your health care provider might adjust your medications if they’re contributing to the problem. Many nasal and sinus conditions and dental problems can be treated as well. If you smoke, quitting can help restore your sense of smell.

• #2 Smell training is brain training, parosmia success — and five other insights from a new UAB clinic – UAB Reporter

  https://www.uab.edu/reporter/patient-care/advances/item/10005-smell-training-is-brain-training-parosmia-success-and-five-other-insights-from-a-new-uab-clinic

  Cho recommends smell training for these patients, but he has also used drug treatment specifically the anti-seizure medicine gabapentin with significant success. […] The outlook for most patients is ultimately positive. After two years, about 80 percent to 90 percent recover, Cho said. […] Research on new treatments for smell loss and the underlying causes of the problem has been turbocharged by the COVID pandemic.

• #2 Lost or changed sense of smell

  https://www.nhs.uk/conditions/lost-or-changed-sense-smell/

  A treatment called smell training can help some people. […] Treating the cause might help. For example, steroid nasal sprays or drops might help if you have sinusitis or nasal polyps. […] Your sense of smell may go back to normal in a few weeks or months. […] Sometimes changes in sense of smell cannot be treated and may be permanent.

• #2 Lost or changed sense of smell | nidirect

  https://www.nidirect.gov.uk/conditions/lost-or-changed-sense-smell

  A change in your sense of smell can be unpleasant and affect how things taste. But it isn’t usually serious and may get better in a few weeks or months. See your GP if your sense of smell doesn’t go back to normal in a few weeks. […] You should see your GP if your sense of smell doesn’t go back to normal in a few weeks. […] Treating the cause might help. For example, steroid nasal sprays or drops might help if you have sinusitis or nasal polyps. […] A treatment called „smell training” can also help some people. […] Sometimes changes in sense of smell can’t be treated and may be permanent.

• #2 Treatments | Stanford Health Care

  https://stanfordhealthcare.org/medical-conditions/ear-nose-and-throat/anosmia-loss-of-smell/treatments.html

  Anosmia Treatments […] Our experienced team works with you to identify the cause of smell loss so we can deliver effective treatments. If you need surgery, we lead the nation in advanced procedures and minimally invasive techniques. Youll receive customized treatments and compassionate support. […] […] […] Treatment for loss of smell depends on whats causing the disorder. In many cases, treating the cause restores the sense of smell. If you have an upper respiratory infection, your doctor will treat the infection with medications, fluids, and rest. If you have a tumor, nasal polyps, or another type of blockage, your doctor may recommend surgery. […] […] […] If you experience symptoms of anosmia or hyposmia, seek medical care right away. Delaying treatment for smell disorders could result in permanent loss of smell. Our team will recommend the most appropriate treatment plan, which may include:

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