Materiały źródłowe

• #1 Trichomoniasis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK534826/

  Patients treated with metronidazole have a 90% to 95% cure rate. The cure rates are even higher when the sexual partner is treated. […] Unfortunately, recurrent infections are common in sexually active individuals. Trichomoniasis is strongly associated with the presence of other STIs, including HIV, gonorrhea, human papillomavirus (HPV), herpes, and chlamydia. Pregnant women are at risk for preterm delivery, low birth weight infants, and premature rupture of membranes. There is also a high risk of developing pelvic inflammatory disease.

• #2 Development and validation of a predictive model for the risk of developing trichomonas vaginitis in women | Scientific Reports

  https://www.nature.com/articles/s41598-022-24396-y

  Trichomonas vaginitis (TV) is the most common non-viral sexually transmitted infection (STI) worldwide. […] The prediction model was evaluated in terms of identification, calibration, and clinical utility using the C-index, calibration plots, decision curve analysis, and internal validation. […] The C-index of the TV risk prediction model was 0.732 (95% confidence interval: 0.6950.768). It showed good discriminatory and predictive power. […] The established TV prediction model easily, accurately, and quickly predicts the risk of TV onset. […] Therefore, there are a series of clinical concerns associated with the high incidence of TV, its insidious clinical symptoms, high underdiagnosis rate, high recurrence rate, and the risk of potential complications. […] This study aimed to create a simple, valid and feasible predictive tool to evaluate the risk of developing TV in women based on a large sample of community-based population screening data, that would be of benefit to a larger number of patients.

• #2 Trichomoniasis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/230617-overview

  Trichomoniasis can usually be treated quickly and effectively. Recurrent infections are common in sexually active patients. One study found that 17% of sexually active patients with T vaginalis infection were reinfected at 3-month follow-up. Multiple randomized trials have found that this rate of reinfection can be significantly reduced through expedited partner therapy. […] T vaginalis infection is also strongly associated with the presence of other STIs, including gonorrhea, chlamydia, and sexually transmitted viruses. T vaginalis infection has even been shown to increase a patients susceptibility to sexually transmitted viruses, including herpes simplex virus, human papillomavirus, and HIV. Persons with trichomoniasis are twice as likely to develop HIV infection as the general population. One potential explanation for this is that T vaginalis disrupts the epithelial monolayer, leading to increased passage of the HIV virus. Another posits that T vaginalis induces immune activation, specifically lymphocyte activation and replication and cytokine production, leading to increased viral replication in HIV-infected cells. Further research is needed to clarify the exact mechanism by which T vaginalis increases the risk for HIV infection.

• #3 Trichomoniasis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/230617-overview

  Trichomoniasis can usually be treated quickly and effectively. Recurrent infections are common in sexually active patients. One study found that 17% of sexually active patients with T vaginalis infection were reinfected at 3-month follow-up. Multiple randomized trials have found that this rate of reinfection can be significantly reduced through expedited partner therapy. […] T vaginalis infection is also strongly associated with the presence of other STIs, including gonorrhea, chlamydia, and sexually transmitted viruses. T vaginalis infection has even been shown to increase a patients susceptibility to sexually transmitted viruses, including herpes simplex virus, human papillomavirus, and HIV. Persons with trichomoniasis are twice as likely to develop HIV infection as the general population. One potential explanation for this is that T vaginalis disrupts the epithelial monolayer, leading to increased passage of the HIV virus. Another posits that T vaginalis induces immune activation, specifically lymphocyte activation and replication and cytokine production, leading to increased viral replication in HIV-infected cells. Further research is needed to clarify the exact mechanism by which T vaginalis increases the risk for HIV infection.

• #4 Trichomonas vaginalis follow-up and persistence in Colombian women | Scientific Reports

  https://www.nature.com/articles/s41598-021-02135-z

  Trichomonas vaginalis (TV), the most common non-viral sexually-transmitted infection is considered a neglected infection and its epidemiology is not well known. […] Women suffering HPV had a greater risk of TV-infection (aHR 1.59), high viral-load (102) for HPV-16 being related to a greater risk of persistent parasite infection; a high viral load (102) for HPV-18 and -33 was related to a lower probability of TV-clearance. […] Women aged 35- to 49-years-old (aHR 2.08), increased years of sexual activity (aHR 1.10), multiple sexual partners (aHR 8.86) and multiparous women (aHR 3.85) led to a greater probability of persistence. […] Women whose cervical findings worsened had a 9.99 greater probability of TV-persistence. […] The results suggested that routine TV detection should be considered regarding populations at risk of infection.

• #5 Trichomonas vaginalis follow-up and persistence in Colombian women | Scientific Reports

  https://www.nature.com/articles/s41598-021-02135-z

  A significant association was found between lesion progression and parasite persistence. […] This study has reported a greater probability of HPV-infected women acquiring TV and its persistence. […] Our results showed that HPV-16, -31 and -33 were mainly related to the clinical course of TV infection, an association previously described for TV and HPV-16. […] The importance of the amount of HPV copies has been highlighted since their increase has been seen to be related to the appearance of cervical lesions (a dose-response relationship) and a greater probability of STI transmission. […] Our results showed that host factors (age and increased years of active sexual life) promoted TV-persistence. […] Other factors regarding host behaviour (i.e. multiparity and the amount of sexual partners) were seen to be related to parasite persistence. […] This study has indicated significant TV infection outcome-related associations.

• #6 Development and validation of a predictive model for the risk of developing trichomonas vaginitis in women | Scientific Reports

  https://www.nature.com/articles/s41598-022-24396-y

  Trichomonas vaginitis (TV) is the most common non-viral sexually transmitted infection (STI) worldwide. […] The prediction model was evaluated in terms of identification, calibration, and clinical utility using the C-index, calibration plots, decision curve analysis, and internal validation. […] The C-index of the TV risk prediction model was 0.732 (95% confidence interval: 0.6950.768). It showed good discriminatory and predictive power. […] The established TV prediction model easily, accurately, and quickly predicts the risk of TV onset. […] Therefore, there are a series of clinical concerns associated with the high incidence of TV, its insidious clinical symptoms, high underdiagnosis rate, high recurrence rate, and the risk of potential complications. […] This study aimed to create a simple, valid and feasible predictive tool to evaluate the risk of developing TV in women based on a large sample of community-based population screening data, that would be of benefit to a larger number of patients.

• #7 Development and validation of a predictive model for the risk of developing trichomonas vaginitis in women | Scientific Reports

  https://www.nature.com/articles/s41598-022-24396-y

  The calibration curve of the predicted female TV risk nomogram showed good agreement with that of the cohort. […] The C-index of the predicted nomogram for this cohort was 0.732 (95% confidence interval: 0.6950.768) and was confirmed to be 0.707 by bootstrap validation, indicating the good discriminatory power of the model. […] This predictive model can be used to assess the risk of TV development in women. […] The nomogram developed in this study indicates that HPV infection is a key protective factor against Trichomonas vaginalis infection. […] Older age, menopause, history of spontaneous abortion, and history of gynaecological surgery were independent risk factors and HPV infection was an independent protective factor in this study. […] By combining these ten predictors, a model was constructed to predict model for predicting the occurrence of TV, which is suitable for use in TV clinical risk assessment studies.

• #8 Development and validation of a predictive model for the risk of developing trichomonas vaginitis in women | Scientific Reports

  https://www.nature.com/articles/s41598-022-24396-y

  The calibration curve of the predicted female TV risk nomogram showed good agreement with that of the cohort. […] The C-index of the predicted nomogram for this cohort was 0.732 (95% confidence interval: 0.6950.768) and was confirmed to be 0.707 by bootstrap validation, indicating the good discriminatory power of the model. […] This predictive model can be used to assess the risk of TV development in women. […] The nomogram developed in this study indicates that HPV infection is a key protective factor against Trichomonas vaginalis infection. […] Older age, menopause, history of spontaneous abortion, and history of gynaecological surgery were independent risk factors and HPV infection was an independent protective factor in this study. […] By combining these ten predictors, a model was constructed to predict model for predicting the occurrence of TV, which is suitable for use in TV clinical risk assessment studies.

• #9 Development and validation of a predictive model for the risk of developing trichomonas vaginitis in women | Scientific Reports

  https://www.nature.com/articles/s41598-022-24396-y

  The calibration curve of the predicted female TV risk nomogram showed good agreement with that of the cohort. […] The C-index of the predicted nomogram for this cohort was 0.732 (95% confidence interval: 0.6950.768) and was confirmed to be 0.707 by bootstrap validation, indicating the good discriminatory power of the model. […] This predictive model can be used to assess the risk of TV development in women. […] The nomogram developed in this study indicates that HPV infection is a key protective factor against Trichomonas vaginalis infection. […] Older age, menopause, history of spontaneous abortion, and history of gynaecological surgery were independent risk factors and HPV infection was an independent protective factor in this study. […] By combining these ten predictors, a model was constructed to predict model for predicting the occurrence of TV, which is suitable for use in TV clinical risk assessment studies.

• #10 Development and validation of a predictive model for the risk of developing trichomonas vaginitis in women | Scientific Reports

  https://www.nature.com/articles/s41598-022-24396-y

  The calibration curve of the predicted female TV risk nomogram showed good agreement with that of the cohort. […] The C-index of the predicted nomogram for this cohort was 0.732 (95% confidence interval: 0.6950.768) and was confirmed to be 0.707 by bootstrap validation, indicating the good discriminatory power of the model. […] This predictive model can be used to assess the risk of TV development in women. […] The nomogram developed in this study indicates that HPV infection is a key protective factor against Trichomonas vaginalis infection. […] Older age, menopause, history of spontaneous abortion, and history of gynaecological surgery were independent risk factors and HPV infection was an independent protective factor in this study. […] By combining these ten predictors, a model was constructed to predict model for predicting the occurrence of TV, which is suitable for use in TV clinical risk assessment studies.

• #11 Trichomoniasis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK534826/

  Patients treated with metronidazole have a 90% to 95% cure rate. The cure rates are even higher when the sexual partner is treated. […] Unfortunately, recurrent infections are common in sexually active individuals. Trichomoniasis is strongly associated with the presence of other STIs, including HIV, gonorrhea, human papillomavirus (HPV), herpes, and chlamydia. Pregnant women are at risk for preterm delivery, low birth weight infants, and premature rupture of membranes. There is also a high risk of developing pelvic inflammatory disease.

• #12 Trichomoniasis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/230617-overview

  Trichomoniasis can usually be treated quickly and effectively. Recurrent infections are common in sexually active patients. One study found that 17% of sexually active patients with T vaginalis infection were reinfected at 3-month follow-up. Multiple randomized trials have found that this rate of reinfection can be significantly reduced through expedited partner therapy. […] T vaginalis infection is also strongly associated with the presence of other STIs, including gonorrhea, chlamydia, and sexually transmitted viruses. T vaginalis infection has even been shown to increase a patients susceptibility to sexually transmitted viruses, including herpes simplex virus, human papillomavirus, and HIV. Persons with trichomoniasis are twice as likely to develop HIV infection as the general population. One potential explanation for this is that T vaginalis disrupts the epithelial monolayer, leading to increased passage of the HIV virus. Another posits that T vaginalis induces immune activation, specifically lymphocyte activation and replication and cytokine production, leading to increased viral replication in HIV-infected cells. Further research is needed to clarify the exact mechanism by which T vaginalis increases the risk for HIV infection.

• #13 Trichomoniasis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/230617-overview

  Trichomoniasis can usually be treated quickly and effectively. Recurrent infections are common in sexually active patients. One study found that 17% of sexually active patients with T vaginalis infection were reinfected at 3-month follow-up. Multiple randomized trials have found that this rate of reinfection can be significantly reduced through expedited partner therapy. […] T vaginalis infection is also strongly associated with the presence of other STIs, including gonorrhea, chlamydia, and sexually transmitted viruses. T vaginalis infection has even been shown to increase a patients susceptibility to sexually transmitted viruses, including herpes simplex virus, human papillomavirus, and HIV. Persons with trichomoniasis are twice as likely to develop HIV infection as the general population. One potential explanation for this is that T vaginalis disrupts the epithelial monolayer, leading to increased passage of the HIV virus. Another posits that T vaginalis induces immune activation, specifically lymphocyte activation and replication and cytokine production, leading to increased viral replication in HIV-infected cells. Further research is needed to clarify the exact mechanism by which T vaginalis increases the risk for HIV infection.

• #14 Trichomonas vaginalis follow-up and persistence in Colombian women | Scientific Reports

  https://www.nature.com/articles/s41598-021-02135-z

  Trichomonas vaginalis (TV), the most common non-viral sexually-transmitted infection is considered a neglected infection and its epidemiology is not well known. […] Women suffering HPV had a greater risk of TV-infection (aHR 1.59), high viral-load (102) for HPV-16 being related to a greater risk of persistent parasite infection; a high viral load (102) for HPV-18 and -33 was related to a lower probability of TV-clearance. […] Women aged 35- to 49-years-old (aHR 2.08), increased years of sexual activity (aHR 1.10), multiple sexual partners (aHR 8.86) and multiparous women (aHR 3.85) led to a greater probability of persistence. […] Women whose cervical findings worsened had a 9.99 greater probability of TV-persistence. […] The results suggested that routine TV detection should be considered regarding populations at risk of infection.

• #15 Trichomonas vaginalis follow-up and persistence in Colombian women | Scientific Reports

  https://www.nature.com/articles/s41598-021-02135-z

  A significant association was found between lesion progression and parasite persistence. […] This study has reported a greater probability of HPV-infected women acquiring TV and its persistence. […] Our results showed that HPV-16, -31 and -33 were mainly related to the clinical course of TV infection, an association previously described for TV and HPV-16. […] The importance of the amount of HPV copies has been highlighted since their increase has been seen to be related to the appearance of cervical lesions (a dose-response relationship) and a greater probability of STI transmission. […] Our results showed that host factors (age and increased years of active sexual life) promoted TV-persistence. […] Other factors regarding host behaviour (i.e. multiparity and the amount of sexual partners) were seen to be related to parasite persistence. […] This study has indicated significant TV infection outcome-related associations.

• #16 Trichomoniasis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK534826/

  Patients treated with metronidazole have a 90% to 95% cure rate. The cure rates are even higher when the sexual partner is treated. […] Unfortunately, recurrent infections are common in sexually active individuals. Trichomoniasis is strongly associated with the presence of other STIs, including HIV, gonorrhea, human papillomavirus (HPV), herpes, and chlamydia. Pregnant women are at risk for preterm delivery, low birth weight infants, and premature rupture of membranes. There is also a high risk of developing pelvic inflammatory disease.

• #17 Trichomoniasis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/230617-overview

  Women may experience various complications associated with trichomoniasis. One study reported a higher risk of pelvic inflammatory disease in women with trichomoniasis. Other studies have reported a 1.9-fold risk of tubal infertility in women with trichomoniasis. Trichomoniasis may also play a role in cervical neoplasia and postoperative infections. […] Pregnant women with T vaginalis infection are at an especially high risk for adverse outcomes, which may include the following: Preterm delivery, Low birth-weight offspring, Premature rupture of membranes, Intrauterine infection, Respiratory or genital T vaginalis infection in the newborn. […] T vaginalis infection may also increase the likelihood of vertical HIV transmission owing to disruption of the vaginal mucosa. […] Researchers conducted a study involving 197 male volunteers seeking medical care for infertility issues, collecting urine and semen samples to investigate the frequency of trichomoniasis. The average age of participants ranged from 36 to 40 years, with 181 individuals experiencing fertility problems compared to 16 with normal fertility. Spermogram analysis revealed that 48% of participants had non-motile or progressive sperm, and 48% exhibited abnormalities in sperm morphology. Whereas microscopic examination did not detect T vaginalis, molecular analysis using PCR and sequencing identified one case of trichomoniasis in a 33-year-old infertile man, who had only 0.3% normal sperm and 19% motility. The isolated T vaginalis was classified as the G genotype.

• #18 Trichomoniasis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK534826/

  Patients treated with metronidazole have a 90% to 95% cure rate. The cure rates are even higher when the sexual partner is treated. […] Unfortunately, recurrent infections are common in sexually active individuals. Trichomoniasis is strongly associated with the presence of other STIs, including HIV, gonorrhea, human papillomavirus (HPV), herpes, and chlamydia. Pregnant women are at risk for preterm delivery, low birth weight infants, and premature rupture of membranes. There is also a high risk of developing pelvic inflammatory disease.

• #19 Trichomoniasis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/230617-overview

  Women may experience various complications associated with trichomoniasis. One study reported a higher risk of pelvic inflammatory disease in women with trichomoniasis. Other studies have reported a 1.9-fold risk of tubal infertility in women with trichomoniasis. Trichomoniasis may also play a role in cervical neoplasia and postoperative infections. […] Pregnant women with T vaginalis infection are at an especially high risk for adverse outcomes, which may include the following: Preterm delivery, Low birth-weight offspring, Premature rupture of membranes, Intrauterine infection, Respiratory or genital T vaginalis infection in the newborn. […] T vaginalis infection may also increase the likelihood of vertical HIV transmission owing to disruption of the vaginal mucosa. […] Researchers conducted a study involving 197 male volunteers seeking medical care for infertility issues, collecting urine and semen samples to investigate the frequency of trichomoniasis. The average age of participants ranged from 36 to 40 years, with 181 individuals experiencing fertility problems compared to 16 with normal fertility. Spermogram analysis revealed that 48% of participants had non-motile or progressive sperm, and 48% exhibited abnormalities in sperm morphology. Whereas microscopic examination did not detect T vaginalis, molecular analysis using PCR and sequencing identified one case of trichomoniasis in a 33-year-old infertile man, who had only 0.3% normal sperm and 19% motility. The isolated T vaginalis was classified as the G genotype.

• #20 Trichomoniasis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/230617-overview

  Women may experience various complications associated with trichomoniasis. One study reported a higher risk of pelvic inflammatory disease in women with trichomoniasis. Other studies have reported a 1.9-fold risk of tubal infertility in women with trichomoniasis. Trichomoniasis may also play a role in cervical neoplasia and postoperative infections. […] Pregnant women with T vaginalis infection are at an especially high risk for adverse outcomes, which may include the following: Preterm delivery, Low birth-weight offspring, Premature rupture of membranes, Intrauterine infection, Respiratory or genital T vaginalis infection in the newborn. […] T vaginalis infection may also increase the likelihood of vertical HIV transmission owing to disruption of the vaginal mucosa. […] Researchers conducted a study involving 197 male volunteers seeking medical care for infertility issues, collecting urine and semen samples to investigate the frequency of trichomoniasis. The average age of participants ranged from 36 to 40 years, with 181 individuals experiencing fertility problems compared to 16 with normal fertility. Spermogram analysis revealed that 48% of participants had non-motile or progressive sperm, and 48% exhibited abnormalities in sperm morphology. Whereas microscopic examination did not detect T vaginalis, molecular analysis using PCR and sequencing identified one case of trichomoniasis in a 33-year-old infertile man, who had only 0.3% normal sperm and 19% motility. The isolated T vaginalis was classified as the G genotype.

• #21 Trichomoniasis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/230617-overview

  Women may experience various complications associated with trichomoniasis. One study reported a higher risk of pelvic inflammatory disease in women with trichomoniasis. Other studies have reported a 1.9-fold risk of tubal infertility in women with trichomoniasis. Trichomoniasis may also play a role in cervical neoplasia and postoperative infections. […] Pregnant women with T vaginalis infection are at an especially high risk for adverse outcomes, which may include the following: Preterm delivery, Low birth-weight offspring, Premature rupture of membranes, Intrauterine infection, Respiratory or genital T vaginalis infection in the newborn. […] T vaginalis infection may also increase the likelihood of vertical HIV transmission owing to disruption of the vaginal mucosa. […] Researchers conducted a study involving 197 male volunteers seeking medical care for infertility issues, collecting urine and semen samples to investigate the frequency of trichomoniasis. The average age of participants ranged from 36 to 40 years, with 181 individuals experiencing fertility problems compared to 16 with normal fertility. Spermogram analysis revealed that 48% of participants had non-motile or progressive sperm, and 48% exhibited abnormalities in sperm morphology. Whereas microscopic examination did not detect T vaginalis, molecular analysis using PCR and sequencing identified one case of trichomoniasis in a 33-year-old infertile man, who had only 0.3% normal sperm and 19% motility. The isolated T vaginalis was classified as the G genotype.

• #22 Trichomoniasis: Background, Pathophysiology, Etiology

  https://emedicine.medscape.com/article/230617-overview

  The study highlights that trichomoniasis in males has often been deemed unimportant, with the assumption that it would resolve on its own. However, the findings suggest that parasites may be a contributing factor to male infertility, although the extent of their impact remains unclear. This investigation underscores the effectiveness of molecular techniques in detecting trichomoniasis in males, indicating a need for further exploration of its role in infertility.

• #23 Trichomonas vaginalis follow-up and persistence in Colombian women | Scientific Reports

  https://www.nature.com/articles/s41598-021-02135-z

  Trichomonas vaginalis (TV), the most common non-viral sexually-transmitted infection is considered a neglected infection and its epidemiology is not well known. […] Women suffering HPV had a greater risk of TV-infection (aHR 1.59), high viral-load (102) for HPV-16 being related to a greater risk of persistent parasite infection; a high viral load (102) for HPV-18 and -33 was related to a lower probability of TV-clearance. […] Women aged 35- to 49-years-old (aHR 2.08), increased years of sexual activity (aHR 1.10), multiple sexual partners (aHR 8.86) and multiparous women (aHR 3.85) led to a greater probability of persistence. […] Women whose cervical findings worsened had a 9.99 greater probability of TV-persistence. […] The results suggested that routine TV detection should be considered regarding populations at risk of infection.

• #24 Trichomonas vaginalis follow-up and persistence in Colombian women | Scientific Reports

  https://www.nature.com/articles/s41598-021-02135-z

  A significant association was found between lesion progression and parasite persistence. […] This study has reported a greater probability of HPV-infected women acquiring TV and its persistence. […] Our results showed that HPV-16, -31 and -33 were mainly related to the clinical course of TV infection, an association previously described for TV and HPV-16. […] The importance of the amount of HPV copies has been highlighted since their increase has been seen to be related to the appearance of cervical lesions (a dose-response relationship) and a greater probability of STI transmission. […] Our results showed that host factors (age and increased years of active sexual life) promoted TV-persistence. […] Other factors regarding host behaviour (i.e. multiparity and the amount of sexual partners) were seen to be related to parasite persistence. […] This study has indicated significant TV infection outcome-related associations.

• #25 Trichomonas vaginalis follow-up and persistence in Colombian women | Scientific Reports

  https://www.nature.com/articles/s41598-021-02135-z

  A significant association was found between lesion progression and parasite persistence. […] This study has reported a greater probability of HPV-infected women acquiring TV and its persistence. […] Our results showed that HPV-16, -31 and -33 were mainly related to the clinical course of TV infection, an association previously described for TV and HPV-16. […] The importance of the amount of HPV copies has been highlighted since their increase has been seen to be related to the appearance of cervical lesions (a dose-response relationship) and a greater probability of STI transmission. […] Our results showed that host factors (age and increased years of active sexual life) promoted TV-persistence. […] Other factors regarding host behaviour (i.e. multiparity and the amount of sexual partners) were seen to be related to parasite persistence. […] This study has indicated significant TV infection outcome-related associations.

• #26 Development and validation of a predictive model for the risk of developing trichomonas vaginitis in women | Scientific Reports

  https://www.nature.com/articles/s41598-022-24396-y

  Trichomonas vaginitis (TV) is the most common non-viral sexually transmitted infection (STI) worldwide. […] The prediction model was evaluated in terms of identification, calibration, and clinical utility using the C-index, calibration plots, decision curve analysis, and internal validation. […] The C-index of the TV risk prediction model was 0.732 (95% confidence interval: 0.6950.768). It showed good discriminatory and predictive power. […] The established TV prediction model easily, accurately, and quickly predicts the risk of TV onset. […] Therefore, there are a series of clinical concerns associated with the high incidence of TV, its insidious clinical symptoms, high underdiagnosis rate, high recurrence rate, and the risk of potential complications. […] This study aimed to create a simple, valid and feasible predictive tool to evaluate the risk of developing TV in women based on a large sample of community-based population screening data, that would be of benefit to a larger number of patients.

• #27 Development and validation of a predictive model for the risk of developing trichomonas vaginitis in women | Scientific Reports

  https://www.nature.com/articles/s41598-022-24396-y

  Trichomonas vaginitis (TV) is the most common non-viral sexually transmitted infection (STI) worldwide. […] The prediction model was evaluated in terms of identification, calibration, and clinical utility using the C-index, calibration plots, decision curve analysis, and internal validation. […] The C-index of the TV risk prediction model was 0.732 (95% confidence interval: 0.6950.768). It showed good discriminatory and predictive power. […] The established TV prediction model easily, accurately, and quickly predicts the risk of TV onset. […] Therefore, there are a series of clinical concerns associated with the high incidence of TV, its insidious clinical symptoms, high underdiagnosis rate, high recurrence rate, and the risk of potential complications. […] This study aimed to create a simple, valid and feasible predictive tool to evaluate the risk of developing TV in women based on a large sample of community-based population screening data, that would be of benefit to a larger number of patients.

• #28 Trichomonas vaginalis follow-up and persistence in Colombian women | Scientific Reports

  https://www.nature.com/articles/s41598-021-02135-z

  Trichomonas vaginalis (TV), the most common non-viral sexually-transmitted infection is considered a neglected infection and its epidemiology is not well known. […] Women suffering HPV had a greater risk of TV-infection (aHR 1.59), high viral-load (102) for HPV-16 being related to a greater risk of persistent parasite infection; a high viral load (102) for HPV-18 and -33 was related to a lower probability of TV-clearance. […] Women aged 35- to 49-years-old (aHR 2.08), increased years of sexual activity (aHR 1.10), multiple sexual partners (aHR 8.86) and multiparous women (aHR 3.85) led to a greater probability of persistence. […] Women whose cervical findings worsened had a 9.99 greater probability of TV-persistence. […] The results suggested that routine TV detection should be considered regarding populations at risk of infection.

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