Materiały źródłowe

• #1 Bipolar Disorders: Evaluation and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2021/0215/p227.html

  Bipolar disorders are common, recurrent mental health conditions of variable severity that are difficult to diagnose. […] Pharmacotherapy with mood stabilizers, such as lithium, anticonvulsants, and antipsychotics, is a first-line treatment that should be continued indefinitely because of the risk of patient relapse. […] Psychotherapy is a useful adjunct to pharmacotherapy. […] Patients and their support systems should be educated about the chronic nature of this illness, possible relapse, suicidality, environmental triggers (e.g., seasonal light changes, shift work, other circadian disruption), and the effectiveness of early intervention to reduce complications. […] It is recommended that pharmacotherapy be continued indefinitely. […] Comanagement with a psychiatrist can aid the primary care physician in navigating diagnostic and therapeutic challenges, including relapse, treatment resistance, comorbid psychiatric conditions, and the risk of self-harm.

• #2 Treatment of bipolar disorder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3876031/

  Treatment of bipolar disorder conventionally focuses on acute stabilisation, in which the goal is to bring a patient with mania or depression to a symptomatic recovery with euthymic (stable) mood; and on maintenance, in which the goals are relapse prevention, reduction of subthreshold symptoms, and enhanced social and occupational functioning. […] Treatment of both phases of the illness can be complex, because the same treatments that alleviate depression can cause mania, hypomania, or rapid cycling (defined as four or more episodes in 12 months), and the treatments that reduce mania might cause rebound depressive episodes. […] We focus on contemporary issues in the acute and maintenance treatment of bipolar disorder. […] Despite a substantial expansion of research into bipolar disorder and potential treatments during the past 2 decades, true advances have been few. The development of effective treatments for bipolar disorder is hampered by our scarce knowledge of basic disease mechanisms and the consequent absence of validated pharmacological targets, and unconvincing animal or human experimental drug models. […] Most newly introduced treatments for bipolar disorder, whether pharmacological or psychological, have been based on an extension of use from another disorder, eg, antipsychotics in mania and antidepressants or cognitive-behavioural therapy for bipolar depression.

• #3 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  Bipolar disorder is treated with three main classes of medication: mood stabilizers, antipsychotics, and, while their safety and effectiveness for the condition are sometimes controversial, antidepressants. […] Typically, treatment entails a combination of at least one mood-stabilizing drug and/or atypical antipsychotic, plus psychotherapy. […] The most widely used drugs for the treatment of bipolar disorder include lithium carbonate and valproic acid (also known as Depakote or generically as divalproex). […] Lithium carbonate can be remarkably effective in reducing mania, although doctors still do not know precisely how it works. […] Valproic acid (Depakote) is a mood stabilizer that is helpful in treating the manic or mixed phases of bipolar disorder, along with carbamazepine (Equetro, Tegretol), another antiepileptic drug.

• #4

  https://www.who.int/news-room/fact-sheets/detail/bipolar-disorder

  Mood stabilizers (such as lithium, valproate) and antipsychotics are proven to help manage acute mania. […] Antidepressants should not be taken during a manic episode and they may be combined with mood stabilizers or antipsychotics during episodes of depression. […] Adults with bipolar disorder who are in complete remission (no symptoms) usually need to continue with mood stabilizers or antipsychotic medicines for at least six months. Those experiencing multiple episodes of mania and depression will usually require longer-term treatment to minimize relapses. […] Psychological interventions (e.g. cognitive behavioural therapy, interpersonal therapy, psychoeducation) can effectively reduce depressive symptoms and the possibility of them coming back. […] Recovery-oriented psychosocial interventions include supported employment, supported housing, peer support, and social and life skills training. They serve to promote hope and to support the autonomy, personal empowerment and social inclusion of people with bipolar disorder. […] Medicines and psychological or psychosocial interventions should be tailored to the needs of the person and combined for best outcomes.

• #5 Treatment of bipolar disorder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3876031/

  The treatment of bipolar depression is a major challenge, with few treatments of proven efficacy and, in particular, substantial controversy about the role of antidepressant drugs. […] A recent updated meta-analysis of antidepressants in bipolar depression reported a pooled effect no different from placebo with statistically significant heterogeneity. […] Therefore, to conclude that no antidepressant agent is effective in bipolar depression is probably premature, although the emerging evidence suggests that paroxetine is ineffective. […] Lithium, introduced by John Cade in 1949, remains the best established long-term treatment for bipolar disorder. […] A meta-analysis of five placebo-controlled lithium maintenance trials showed that lithium reduces the risk of manic relapses by 38% and depressive relapse by 28%. […] However, the benefits of lithium are restricted by adverse effects and a low therapeutic index.

• #6 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  Bipolar disorder is treated with three main classes of medication: mood stabilizers, antipsychotics, and, while their safety and effectiveness for the condition are sometimes controversial, antidepressants. […] Typically, treatment entails a combination of at least one mood-stabilizing drug and/or atypical antipsychotic, plus psychotherapy. […] The most widely used drugs for the treatment of bipolar disorder include lithium carbonate and valproic acid (also known as Depakote or generically as divalproex). […] Lithium carbonate can be remarkably effective in reducing mania, although doctors still do not know precisely how it works. […] Valproic acid (Depakote) is a mood stabilizer that is helpful in treating the manic or mixed phases of bipolar disorder, along with carbamazepine (Equetro, Tegretol), another antiepileptic drug.

• #7 Medications for Treatment of Bipolar Disorders – Psychiatric Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/psychiatric-disorders/mood-disorders/medications-for-treatment-of-bipolar-disorders

  Choice of pharmacologic agents to treat bipolar disorders can be difficult because all medications can potentially have significant adverse effects, drug interactions are common, and no medication is universally effective. Selection should be based on what has previously been effective and well-tolerated in a given patient. […] For severe manic psychosis, in which immediate patient safety and management is compromised, urgent behavioral control usually requires a sedating second-generation antipsychotic, sometimes supplemented initially with a benzodiazepine such as lorazepam or clonazepam. […] For less severe acute episodes in patients without contraindications (eg, renal disorders), lithium is a good first choice for both mania and depressive episodes. […] For bipolar depression, the best evidence suggests using quetiapine, cariprazine, lumateperone, or lurasidone alone or the combination of fluoxetine and olanzapine.

• #8 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  Bipolar disorder is treated with three main classes of medication: mood stabilizers, antipsychotics, and, while their safety and effectiveness for the condition are sometimes controversial, antidepressants. […] Typically, treatment entails a combination of at least one mood-stabilizing drug and/or atypical antipsychotic, plus psychotherapy. […] The most widely used drugs for the treatment of bipolar disorder include lithium carbonate and valproic acid (also known as Depakote or generically as divalproex). […] Lithium carbonate can be remarkably effective in reducing mania, although doctors still do not know precisely how it works. […] Valproic acid (Depakote) is a mood stabilizer that is helpful in treating the manic or mixed phases of bipolar disorder, along with carbamazepine (Equetro, Tegretol), another antiepileptic drug.

• #9 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  Bipolar disorder is treated with three main classes of medication: mood stabilizers, antipsychotics, and, while their safety and effectiveness for the condition are sometimes controversial, antidepressants. […] Typically, treatment entails a combination of at least one mood-stabilizing drug and/or atypical antipsychotic, plus psychotherapy. […] The most widely used drugs for the treatment of bipolar disorder include lithium carbonate and valproic acid (also known as Depakote or generically as divalproex). […] Lithium carbonate can be remarkably effective in reducing mania, although doctors still do not know precisely how it works. […] Valproic acid (Depakote) is a mood stabilizer that is helpful in treating the manic or mixed phases of bipolar disorder, along with carbamazepine (Equetro, Tegretol), another antiepileptic drug.

• #10 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  These drugs may be used alone or in combination with lithium to control symptoms. […] Other antiepileptic drugs, such as gabapentin (Neurontin), oxcarbazepine (Trileptal), or topiramate (Topamax), are regarded as experimental treatments that sometimes have value for symptoms of bipolar disorder or other conditions that often occur with it. […] Haloperidol (Haldol Decanoate) or other newer antipsychotic medications, such as aripiprazole (Abilify), asenapine (Saphris), cariprazine (Vraylar), olanzapine (Zyprexa, Zyprexa Relprevv, and Zyprexa Zydis) or risperidone (Risperdal), are often given to patients as an alternative to lithium or divalproex. […] The antipsychotic medications lumateperone (Caplyta) and quetiapine (Seroquel) are approved to treat bipolar I or II depression. […] While antidepressants remain widely prescribed for bipolar depression, most antidepressants have not been adequately studied in patients with bipolar depression.

• #11 Bipolar depression: a review of treatment options | General Psychiatry

  https://gpsych.bmj.com/content/35/4/e100760

  Lithium is effective in the acute treatment of mania and long-term maintenance of mood and prophylaxis, and may be particularly effective in a subset of patients. […] Of the antiepileptic mood stabilisers, lamotrigine, which has been found to have antidepressant effects in placebo-controlled trials, may be best supported. […] Electroconvulsive therapy (ECT) provides a rapid clinical response and can therefore be used in urgent clinical situations, including, for example, the presence of suicidal behaviour, severe psychosis or catatonia. […] Psychotherapy is well accepted with a relatively low risk of adverse effects. […] In the treatment of BD-D, conventional wisdom is to avoid antidepressants or use them as second-line treatment due to the risk of inducing mania. […] However, many patients with bipolar disorder are prescribed antidepressants in practice, not all antidepressants carry the same risk of conversion to mania, and it is increasingly clear that a subset of patients benefits greatly from treatment with antidepressants.

• #12 Bipolar Disorders: Evaluation and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2021/0215/p227.html

  Monotherapy with antidepressants is contraindicated in patients with mixed features, manic episodes, or bipolar I disorder. […] High-quality evidence supports the use of lithium, lamotrigine (Lamictal), quetiapine, quetiapine in combination with lithium or valproic acid, aripiprazole (Abilify), and olanzapine (Zyprexa) for maintenance therapy in patients who have bipolar disorders. […] Electroconvulsive therapy is effective for mania and psychotic depression. […] Behavioral interventions, including basic psychoeducation and cognitive behavior therapy, are evidence-based adjuncts to pharmacotherapy that improve social function and reduce the need for medications, number of hospitalizations, and relapse rates.

• #13 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  These drugs may be used alone or in combination with lithium to control symptoms. […] Other antiepileptic drugs, such as gabapentin (Neurontin), oxcarbazepine (Trileptal), or topiramate (Topamax), are regarded as experimental treatments that sometimes have value for symptoms of bipolar disorder or other conditions that often occur with it. […] Haloperidol (Haldol Decanoate) or other newer antipsychotic medications, such as aripiprazole (Abilify), asenapine (Saphris), cariprazine (Vraylar), olanzapine (Zyprexa, Zyprexa Relprevv, and Zyprexa Zydis) or risperidone (Risperdal), are often given to patients as an alternative to lithium or divalproex. […] The antipsychotic medications lumateperone (Caplyta) and quetiapine (Seroquel) are approved to treat bipolar I or II depression. […] While antidepressants remain widely prescribed for bipolar depression, most antidepressants have not been adequately studied in patients with bipolar depression.

• #14 Bipolar Disorder (Manic Depression): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/9294-bipolar-disorder

  Certain medications can help manage symptoms of bipolar disorder. You may need to try several different medications, with guidance from your healthcare provider, before finding what works best. […] Medications healthcare providers generally prescribe to treat bipolar disorder include: Mood stabilizers, Second-generation (atypical) neuroleptics (also called antipsychotics), Antidepressants. […] Healthcare providers often prescribe second-generation or atypical neuroleptics (antipsychotics) in combination with a mood stabilizer for people with bipolar disorder. […] Healthcare providers sometimes prescribe antidepressant medication to treat depressive episodes in bipolar disorder, combining the antidepressant with a mood stabilizer to prevent triggering a manic episode. […] Other treatment options your healthcare provider may consider for treating bipolar disorder include: Electroconvulsive therapy (ECT), Transcranial magnetic stimulation (TMS), Thyroid medications, Ketamine treatment, Hospitalization. […] Your healthcare team will likely recommend making lifestyle changes to stop patterns of behavior that worsen the symptoms of bipolar disorder.

• #15 Management of Bipolar Disorder

  https://www.uspharmacist.com/article/management-of-bipolar-disorder

  An antipsychotic may be used as monotherapy or as an adjunct to other treatments for bipolar disorder. […] The utility of antidepressants for bipolar disorder is controversial because there are limited studies supporting its use. Antidepressants are rarely used with mood stabilizers to treat bipolar mania or depression because they can cause mania. […] Pharmacists have a role in promoting the importance of medication adherence and educating patients about how to recognize triggers for their mood episodes.

• #16 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  These drugs may be used alone or in combination with lithium to control symptoms. […] Other antiepileptic drugs, such as gabapentin (Neurontin), oxcarbazepine (Trileptal), or topiramate (Topamax), are regarded as experimental treatments that sometimes have value for symptoms of bipolar disorder or other conditions that often occur with it. […] Haloperidol (Haldol Decanoate) or other newer antipsychotic medications, such as aripiprazole (Abilify), asenapine (Saphris), cariprazine (Vraylar), olanzapine (Zyprexa, Zyprexa Relprevv, and Zyprexa Zydis) or risperidone (Risperdal), are often given to patients as an alternative to lithium or divalproex. […] The antipsychotic medications lumateperone (Caplyta) and quetiapine (Seroquel) are approved to treat bipolar I or II depression. […] While antidepressants remain widely prescribed for bipolar depression, most antidepressants have not been adequately studied in patients with bipolar depression.

• #17 Bipolar Disorder Treatment & Management: Approach Considerations, Indications for Inpatient Management, Considerations for Partial Hospitalization or Day Treatment

  https://emedicine.medscape.com/article/286342-treatment

  Outpatient treatment for patients with bipolar disorder has 4 major goals, as follows: Look at areas of stress and find ways to handle them, Monitor and support the medication, Develop and maintain the therapeutic alliance, Provide education. […] Psychotherapy helps patients with bipolar disorder but does not cure the disorder by itself. […] Appropriate medication depends on the stage of the bipolar disorder the patient is experiencing. […] Combined therapy with an antipsychotic agent and another antimanic medication is recommended for patients with severe mania or mixed episodes, with or without psychotic features. […] Initiate lithium, valproate, carbamazepine, aripiprazole, olanzapine, quetiapine, risperidone, or ziprasidone in patients with mania. […] The American Psychiatric Association’s (APA) 2005 guideline watch for the treatment of patients with bipolar disorder noted that medications having the strongest evidence for efficacy for the acute treatment of depression in BPI are the olanzapine-fluoxetine combination, quetiapine, and lamotrigine.

• #18 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  These drugs may be used alone or in combination with lithium to control symptoms. […] Other antiepileptic drugs, such as gabapentin (Neurontin), oxcarbazepine (Trileptal), or topiramate (Topamax), are regarded as experimental treatments that sometimes have value for symptoms of bipolar disorder or other conditions that often occur with it. […] Haloperidol (Haldol Decanoate) or other newer antipsychotic medications, such as aripiprazole (Abilify), asenapine (Saphris), cariprazine (Vraylar), olanzapine (Zyprexa, Zyprexa Relprevv, and Zyprexa Zydis) or risperidone (Risperdal), are often given to patients as an alternative to lithium or divalproex. […] The antipsychotic medications lumateperone (Caplyta) and quetiapine (Seroquel) are approved to treat bipolar I or II depression. […] While antidepressants remain widely prescribed for bipolar depression, most antidepressants have not been adequately studied in patients with bipolar depression.

• #19 Treatment of bipolar disorder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3876031/

  We review recent developments in the acute and long-term treatment of bipolar disorder and identify promising future routes to therapeutic innovation. Overall, advances in drug treatment remain quite modest. Antipsychotic drugs are effective in the acute treatment of mania; their efficacy in the treatment of depression is variable with the clearest evidence for quetiapine. […] Despite their widespread use, considerable uncertainty and controversy remains about the use of antidepressant drugs in the management of depressive episodes. Lithium has the strongest evidence for long-term relapse prevention; the evidence for anticonvulsants such as divalproex and lamotrigine is less robust and there is much uncertainty about the longer term benefits of antipsychotics. Substantial progress has been made in the development and assessment of adjunctive psychosocial interventions. Long-term maintenance and possibly acute stabilisation of depression can be enhanced by the combination of psychosocial treatments with drugs. […] The development of future treatments should consider both the neurobiological and psychosocial mechanisms underlying the disorder. We should continue to repurpose treatments and to recognise the role of serendipity. We should also investigate optimum combinations of pharmacological and psychotherapeutic treatments at different stages of the illness. […] To be economically viable, existing psychotherapy protocols need to be made briefer and more efficient for improved scalability and sustainability in widespread implementation.

• #20 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  These drugs may be used alone or in combination with lithium to control symptoms. […] Other antiepileptic drugs, such as gabapentin (Neurontin), oxcarbazepine (Trileptal), or topiramate (Topamax), are regarded as experimental treatments that sometimes have value for symptoms of bipolar disorder or other conditions that often occur with it. […] Haloperidol (Haldol Decanoate) or other newer antipsychotic medications, such as aripiprazole (Abilify), asenapine (Saphris), cariprazine (Vraylar), olanzapine (Zyprexa, Zyprexa Relprevv, and Zyprexa Zydis) or risperidone (Risperdal), are often given to patients as an alternative to lithium or divalproex. […] The antipsychotic medications lumateperone (Caplyta) and quetiapine (Seroquel) are approved to treat bipolar I or II depression. […] While antidepressants remain widely prescribed for bipolar depression, most antidepressants have not been adequately studied in patients with bipolar depression.

• #21 Bipolar Disorder Treatment & Management: Approach Considerations, Indications for Inpatient Management, Considerations for Partial Hospitalization or Day Treatment

  https://emedicine.medscape.com/article/286342-treatment

  Outpatient treatment for patients with bipolar disorder has 4 major goals, as follows: Look at areas of stress and find ways to handle them, Monitor and support the medication, Develop and maintain the therapeutic alliance, Provide education. […] Psychotherapy helps patients with bipolar disorder but does not cure the disorder by itself. […] Appropriate medication depends on the stage of the bipolar disorder the patient is experiencing. […] Combined therapy with an antipsychotic agent and another antimanic medication is recommended for patients with severe mania or mixed episodes, with or without psychotic features. […] Initiate lithium, valproate, carbamazepine, aripiprazole, olanzapine, quetiapine, risperidone, or ziprasidone in patients with mania. […] The American Psychiatric Association’s (APA) 2005 guideline watch for the treatment of patients with bipolar disorder noted that medications having the strongest evidence for efficacy for the acute treatment of depression in BPI are the olanzapine-fluoxetine combination, quetiapine, and lamotrigine.

• #22 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  These drugs may be used alone or in combination with lithium to control symptoms. […] Other antiepileptic drugs, such as gabapentin (Neurontin), oxcarbazepine (Trileptal), or topiramate (Topamax), are regarded as experimental treatments that sometimes have value for symptoms of bipolar disorder or other conditions that often occur with it. […] Haloperidol (Haldol Decanoate) or other newer antipsychotic medications, such as aripiprazole (Abilify), asenapine (Saphris), cariprazine (Vraylar), olanzapine (Zyprexa, Zyprexa Relprevv, and Zyprexa Zydis) or risperidone (Risperdal), are often given to patients as an alternative to lithium or divalproex. […] The antipsychotic medications lumateperone (Caplyta) and quetiapine (Seroquel) are approved to treat bipolar I or II depression. […] While antidepressants remain widely prescribed for bipolar depression, most antidepressants have not been adequately studied in patients with bipolar depression.

• #23 Bipolar Disorder Treatment Options – Medications, Therapy, & More

  https://www.therecoveryvillage.com/mental-health/bipolar-disorder/treatment/

  Mood stabilizers are the most common. […] Scientists and mental health professionals do not fully understand how mood stabilizers for bipolar disorder work, but these medications are effective in reducing the frequency of mood episodes. […] Sometimes people with bipolar disorder experience psychotic symptoms and need medication to control them. […] Research shows that Abilify for bipolar disorder is effective in treating and preventing manic and mixed episodes but not as effective in treating bipolar depression. […] Clinicians frequently prescribe antidepressants, including selective serotonin reuptake inhibitors (SSRIs), as bipolar depression medication, though they are usually prescribed in addition to mood stabilizers to avoid triggering manic or hypomanic episodes. […] Anti-anxiety medications like benzodiazepines are sometimes prescribed to people who have bipolar disorder and comorbid anxiety disorders or to address bipolar agitation or insomnia.

• #24 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  These drugs may be used alone or in combination with lithium to control symptoms. […] Other antiepileptic drugs, such as gabapentin (Neurontin), oxcarbazepine (Trileptal), or topiramate (Topamax), are regarded as experimental treatments that sometimes have value for symptoms of bipolar disorder or other conditions that often occur with it. […] Haloperidol (Haldol Decanoate) or other newer antipsychotic medications, such as aripiprazole (Abilify), asenapine (Saphris), cariprazine (Vraylar), olanzapine (Zyprexa, Zyprexa Relprevv, and Zyprexa Zydis) or risperidone (Risperdal), are often given to patients as an alternative to lithium or divalproex. […] The antipsychotic medications lumateperone (Caplyta) and quetiapine (Seroquel) are approved to treat bipolar I or II depression. […] While antidepressants remain widely prescribed for bipolar depression, most antidepressants have not been adequately studied in patients with bipolar depression.

• #25 Bipolar depression: a review of treatment options | General Psychiatry

  https://gpsych.bmj.com/content/35/4/e100760

  Bipolar depression (BD-D) is both common and incredibly challenging to treat. […] Despite this high illness burden, there remain relatively few treatment options approved by the US Food and Drug Administration for BD-D. […] Here, we review commonly used treatments for BD-D, including antipsychotics, classic mood stabilisers, electroconvulsive therapy and psychotherapy. […] Given the enormous burden of BD-D, the development of effective treatment options represents an urgent priority. […] The US Food and Drug Administration (FDA) has approved several drugs for the treatment of BD-D, including a combination of olanzapine plus fluoxetine (OFC) (approved 2003), quetiapine (2008), lurasidone (2013), cariprazine (2019) and lumateperone (2021). […] Here, we review the evidence for and adverse effects of currently approved treatment options.

• #26 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  These drugs may be used alone or in combination with lithium to control symptoms. […] Other antiepileptic drugs, such as gabapentin (Neurontin), oxcarbazepine (Trileptal), or topiramate (Topamax), are regarded as experimental treatments that sometimes have value for symptoms of bipolar disorder or other conditions that often occur with it. […] Haloperidol (Haldol Decanoate) or other newer antipsychotic medications, such as aripiprazole (Abilify), asenapine (Saphris), cariprazine (Vraylar), olanzapine (Zyprexa, Zyprexa Relprevv, and Zyprexa Zydis) or risperidone (Risperdal), are often given to patients as an alternative to lithium or divalproex. […] The antipsychotic medications lumateperone (Caplyta) and quetiapine (Seroquel) are approved to treat bipolar I or II depression. […] While antidepressants remain widely prescribed for bipolar depression, most antidepressants have not been adequately studied in patients with bipolar depression.

• #27 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  These drugs may be used alone or in combination with lithium to control symptoms. […] Other antiepileptic drugs, such as gabapentin (Neurontin), oxcarbazepine (Trileptal), or topiramate (Topamax), are regarded as experimental treatments that sometimes have value for symptoms of bipolar disorder or other conditions that often occur with it. […] Haloperidol (Haldol Decanoate) or other newer antipsychotic medications, such as aripiprazole (Abilify), asenapine (Saphris), cariprazine (Vraylar), olanzapine (Zyprexa, Zyprexa Relprevv, and Zyprexa Zydis) or risperidone (Risperdal), are often given to patients as an alternative to lithium or divalproex. […] The antipsychotic medications lumateperone (Caplyta) and quetiapine (Seroquel) are approved to treat bipolar I or II depression. […] While antidepressants remain widely prescribed for bipolar depression, most antidepressants have not been adequately studied in patients with bipolar depression.

• #28 Bipolar depression: a review of treatment options | General Psychiatry

  https://gpsych.bmj.com/content/35/4/e100760

  Bipolar depression (BD-D) is both common and incredibly challenging to treat. […] Despite this high illness burden, there remain relatively few treatment options approved by the US Food and Drug Administration for BD-D. […] Here, we review commonly used treatments for BD-D, including antipsychotics, classic mood stabilisers, electroconvulsive therapy and psychotherapy. […] Given the enormous burden of BD-D, the development of effective treatment options represents an urgent priority. […] The US Food and Drug Administration (FDA) has approved several drugs for the treatment of BD-D, including a combination of olanzapine plus fluoxetine (OFC) (approved 2003), quetiapine (2008), lurasidone (2013), cariprazine (2019) and lumateperone (2021). […] Here, we review the evidence for and adverse effects of currently approved treatment options.

• #29 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  In general, your doctor may try to keep the use of antidepressants limited and brief. […] Long-term treatment with antidepressants in bipolar disorder tends to be recommended only when the initial response is clear-cut and there are no current or emerging signs of mania or hypomania. […] Some antidepressants — given alone or in combination with other drugs — may trigger a manic episode or cause cycles between depression and mania to be more rapid. […] If an antidepressant is not clearly having a beneficial effect on bipolar depression, there is usually little reason to continue it. […] While medications are usually the cornerstone of treatment for bipolar disorder, ongoing psychotherapy is important to help patients understand and accept the personal and social disruptions of past episodes and better cope with future ones.

• #30 Treatment of bipolar disorder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3876031/

  The treatment of bipolar depression is a major challenge, with few treatments of proven efficacy and, in particular, substantial controversy about the role of antidepressant drugs. […] A recent updated meta-analysis of antidepressants in bipolar depression reported a pooled effect no different from placebo with statistically significant heterogeneity. […] Therefore, to conclude that no antidepressant agent is effective in bipolar depression is probably premature, although the emerging evidence suggests that paroxetine is ineffective. […] Lithium, introduced by John Cade in 1949, remains the best established long-term treatment for bipolar disorder. […] A meta-analysis of five placebo-controlled lithium maintenance trials showed that lithium reduces the risk of manic relapses by 38% and depressive relapse by 28%. […] However, the benefits of lithium are restricted by adverse effects and a low therapeutic index.

• #31 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  In general, your doctor may try to keep the use of antidepressants limited and brief. […] Long-term treatment with antidepressants in bipolar disorder tends to be recommended only when the initial response is clear-cut and there are no current or emerging signs of mania or hypomania. […] Some antidepressants — given alone or in combination with other drugs — may trigger a manic episode or cause cycles between depression and mania to be more rapid. […] If an antidepressant is not clearly having a beneficial effect on bipolar depression, there is usually little reason to continue it. […] While medications are usually the cornerstone of treatment for bipolar disorder, ongoing psychotherapy is important to help patients understand and accept the personal and social disruptions of past episodes and better cope with future ones.

• #32

  https://www.who.int/news-room/fact-sheets/detail/bipolar-disorder

  Mood stabilizers (such as lithium, valproate) and antipsychotics are proven to help manage acute mania. […] Antidepressants should not be taken during a manic episode and they may be combined with mood stabilizers or antipsychotics during episodes of depression. […] Adults with bipolar disorder who are in complete remission (no symptoms) usually need to continue with mood stabilizers or antipsychotic medicines for at least six months. Those experiencing multiple episodes of mania and depression will usually require longer-term treatment to minimize relapses. […] Psychological interventions (e.g. cognitive behavioural therapy, interpersonal therapy, psychoeducation) can effectively reduce depressive symptoms and the possibility of them coming back. […] Recovery-oriented psychosocial interventions include supported employment, supported housing, peer support, and social and life skills training. They serve to promote hope and to support the autonomy, personal empowerment and social inclusion of people with bipolar disorder. […] Medicines and psychological or psychosocial interventions should be tailored to the needs of the person and combined for best outcomes.

• #33

  https://www.who.int/news-room/fact-sheets/detail/bipolar-disorder

  Mood stabilizers (such as lithium, valproate) and antipsychotics are proven to help manage acute mania. […] Antidepressants should not be taken during a manic episode and they may be combined with mood stabilizers or antipsychotics during episodes of depression. […] Adults with bipolar disorder who are in complete remission (no symptoms) usually need to continue with mood stabilizers or antipsychotic medicines for at least six months. Those experiencing multiple episodes of mania and depression will usually require longer-term treatment to minimize relapses. […] Psychological interventions (e.g. cognitive behavioural therapy, interpersonal therapy, psychoeducation) can effectively reduce depressive symptoms and the possibility of them coming back. […] Recovery-oriented psychosocial interventions include supported employment, supported housing, peer support, and social and life skills training. They serve to promote hope and to support the autonomy, personal empowerment and social inclusion of people with bipolar disorder. […] Medicines and psychological or psychosocial interventions should be tailored to the needs of the person and combined for best outcomes.

• #34 Bipolar depression: a review of treatment options | General Psychiatry

  https://gpsych.bmj.com/content/35/4/e100760

  Lithium is effective in the acute treatment of mania and long-term maintenance of mood and prophylaxis, and may be particularly effective in a subset of patients. […] Of the antiepileptic mood stabilisers, lamotrigine, which has been found to have antidepressant effects in placebo-controlled trials, may be best supported. […] Electroconvulsive therapy (ECT) provides a rapid clinical response and can therefore be used in urgent clinical situations, including, for example, the presence of suicidal behaviour, severe psychosis or catatonia. […] Psychotherapy is well accepted with a relatively low risk of adverse effects. […] In the treatment of BD-D, conventional wisdom is to avoid antidepressants or use them as second-line treatment due to the risk of inducing mania. […] However, many patients with bipolar disorder are prescribed antidepressants in practice, not all antidepressants carry the same risk of conversion to mania, and it is increasingly clear that a subset of patients benefits greatly from treatment with antidepressants.

• #35 Medications for Treatment of Bipolar Disorders – Psychiatric Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/psychiatric-disorders/mood-disorders/medications-for-treatment-of-bipolar-disorders

  Choice of pharmacologic agents to treat bipolar disorders can be difficult because all medications can potentially have significant adverse effects, drug interactions are common, and no medication is universally effective. Selection should be based on what has previously been effective and well-tolerated in a given patient. […] For severe manic psychosis, in which immediate patient safety and management is compromised, urgent behavioral control usually requires a sedating second-generation antipsychotic, sometimes supplemented initially with a benzodiazepine such as lorazepam or clonazepam. […] For less severe acute episodes in patients without contraindications (eg, renal disorders), lithium is a good first choice for both mania and depressive episodes. […] For bipolar depression, the best evidence suggests using quetiapine, cariprazine, lumateperone, or lurasidone alone or the combination of fluoxetine and olanzapine.

• #36 Bipolar Disorder Treatment & Management: Approach Considerations, Indications for Inpatient Management, Considerations for Partial Hospitalization or Day Treatment

  https://emedicine.medscape.com/article/286342-treatment

  The VA/DoD considers first-line monotherapy in adult patients with bipolar depression to include quetiapine, lamotrigine, or lithium. […] In patients whose bipolar depression is unresponsive to monotherapy, consider the combination of lithium with lamotrigine. […] Electroconvulsive therapy (ECT) is useful in a number of instances in patients with bipolar disorder, such as when rapid, definitive medical/psychiatric treatment is needed, when the risks of ECT are less than that of other treatments, when the bipolar disorder is refractory to an adequate trial with other treatment strategies, or when the patient prefers this treatment modality. […] Unless the patient with bipolar disorder is on monoamine oxidase inhibitors (MAOIs), no special diet is required. […] The main complications of bipolar disorder are suicide, homicide, and addictions. […] Prevention is the key to the long-term treatment of bipolar disorders as follows: First, use medications such as lithium serve as mood stabilizers, Second, psychoeducation is instituted for the patient and the patients family.

• #37 Medications for Treatment of Bipolar Disorders – Psychiatric Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/psychiatric-disorders/mood-disorders/medications-for-treatment-of-bipolar-disorders

  Choice of pharmacologic agents to treat bipolar disorders can be difficult because all medications can potentially have significant adverse effects, drug interactions are common, and no medication is universally effective. Selection should be based on what has previously been effective and well-tolerated in a given patient. […] For severe manic psychosis, in which immediate patient safety and management is compromised, urgent behavioral control usually requires a sedating second-generation antipsychotic, sometimes supplemented initially with a benzodiazepine such as lorazepam or clonazepam. […] For less severe acute episodes in patients without contraindications (eg, renal disorders), lithium is a good first choice for both mania and depressive episodes. […] For bipolar depression, the best evidence suggests using quetiapine, cariprazine, lumateperone, or lurasidone alone or the combination of fluoxetine and olanzapine.

• #38 Bipolar Disorder Treatment Options – Medications, Therapy, & More

  https://www.therecoveryvillage.com/mental-health/bipolar-disorder/treatment/

  Mood stabilizers are the most common. […] Scientists and mental health professionals do not fully understand how mood stabilizers for bipolar disorder work, but these medications are effective in reducing the frequency of mood episodes. […] Sometimes people with bipolar disorder experience psychotic symptoms and need medication to control them. […] Research shows that Abilify for bipolar disorder is effective in treating and preventing manic and mixed episodes but not as effective in treating bipolar depression. […] Clinicians frequently prescribe antidepressants, including selective serotonin reuptake inhibitors (SSRIs), as bipolar depression medication, though they are usually prescribed in addition to mood stabilizers to avoid triggering manic or hypomanic episodes. […] Anti-anxiety medications like benzodiazepines are sometimes prescribed to people who have bipolar disorder and comorbid anxiety disorders or to address bipolar agitation or insomnia.

• #39 Bipolar Disorder Treatment Options – Medications, Therapy, & More

  https://www.therecoveryvillage.com/mental-health/bipolar-disorder/treatment/

  Mood stabilizers are the most common. […] Scientists and mental health professionals do not fully understand how mood stabilizers for bipolar disorder work, but these medications are effective in reducing the frequency of mood episodes. […] Sometimes people with bipolar disorder experience psychotic symptoms and need medication to control them. […] Research shows that Abilify for bipolar disorder is effective in treating and preventing manic and mixed episodes but not as effective in treating bipolar depression. […] Clinicians frequently prescribe antidepressants, including selective serotonin reuptake inhibitors (SSRIs), as bipolar depression medication, though they are usually prescribed in addition to mood stabilizers to avoid triggering manic or hypomanic episodes. […] Anti-anxiety medications like benzodiazepines are sometimes prescribed to people who have bipolar disorder and comorbid anxiety disorders or to address bipolar agitation or insomnia.

• #40 Bipolar Disorder (Manic Depression): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/9294-bipolar-disorder

  Bipolar disorder is manageable with medications, talk therapy, lifestyle changes and other treatments. […] Treatment can help many people, including those with the most severe forms of bipolar disorder. An effective treatment plan usually includes a combination of the following therapies: Psychotherapy (talk therapy), Medications, Self-management strategies, Helpful lifestyle habits, Other therapies, such as electroconvulsive therapy (ECT) in cases that are poorly responsive to medication or where rapid control of symptoms is necessary to prevent harm. […] Psychotherapy, also called talk therapy, can be an effective part of the treatment plan for people with bipolar disorder. […] Different types of therapy for bipolar disorder include: Psychoeducation, Interpersonal and social rhythm therapy (IPSRT), Family-focused therapy, Cognitive behavioral therapy (CBT).

• #41 Bipolar disorder – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/bipolar-disorder/diagnosis-treatment/drc-20355961

  Treatment is best guided by a medical doctor who diagnoses and treats mental health conditions (psychiatrist) who is skilled in treating bipolar and related disorders. Your care team also may include a psychologist, social worker or psychiatric nurse. […] Bipolar disorder is a lifelong condition, with treatment directed to manage symptoms. […] The main treatments for bipolar disorder include medicines and talk therapy, also known as psychotherapy, to control symptoms. Treatment also may include education and support groups. […] Talk therapy, also called psychotherapy, is a vital part of bipolar disorder treatment. This treatment can be provided in individual, family or group settings. […] Several types of therapy may help, including: Interpersonal and social rhythm therapy. This therapy focuses on stabilizing daily rhythms, including sleeping, waking and eating. A consistent routine helps manage moods. A daily routine for sleep, diet and exercise may help people with bipolar disorder.

• #42

• #43 Treatment of bipolar disorder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3876031/

  Treatment guidelines increasingly suggest that optimum management of bipolar disorder needs integration of pharmacotherapy with targeted psychotherapy. […] Evidence-based models of psychotherapy include cognitive-behavioural therapy, family-focused therapy, interpersonal and social rhythm therapy, group psychoeducation, and systematic care management. […] Most studies of psychotherapy for bipolar disorder are maintenance trials in which patients receive standard drugs and either an experimental psychosocial intervention or usual care. […] A meta-analysis of eight maintenance psychotherapy trials yielded effect sizes ranging from an odds ratio for reductions in any type of mood relapse to enhanced social functioning. […] Substantial progress has been made in the past decade in understanding of the role of psychotherapy in bipolar disorder. […] The next generation of psychotherapy studies will need to systematically assess mediators in the pathways from treatments to changes in illness course.

• #44 Therapy for Bipolar Disorder: Techniques and Efficacy

  https://www.verywellmind.com/therapy-for-bipolar-disorder-techniques-and-efficacy-6742122

  Medication is the mainstay for treating bipolar disorder, but the most successful and durable treatment involves a combination of both medication and therapy. Effective therapies for bipolar disorder include cognitive-behavioral therapy (CBT), family-focused therapy, and interpersonal and social rhythm therapy. Group psychoeducation and peer-support programs are also useful therapies for bipolar disorder. […] But medication on its own isn’t enough to effectively manage symptoms, and keep recurrences of episodes at bay. Instead, the most effective strategy for managing bipolar disorder is to treat it on an ongoing basis with both medication and therapy. […] According to 2019 research published in Psychiatry Online, therapy modalities that have been found to be most effective at treating bipolar disorder include: Psychoeducation, especially in groups, Cognitive-behavioral therapy (CBT), Interpersonal and social rhythm therapy, Family-focused therapy, Peer-support programs.

• #45 Bipolar disorder – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/bipolar-disorder/diagnosis-treatment/drc-20355961

  Cognitive behavioral therapy (CBT). This therapy focuses on identifying unhealthy, negative beliefs and behaviors and replacing them with healthy, positive beliefs and behaviors. CBT can help find what triggers your bipolar episodes. You also learn effective ways to manage stress and cope with upsetting situations. […] Psychoeducation. Learning about bipolar disorder, also known as psychoeducation, can help you and your loved ones know more about the condition. Knowing what’s going on can help you get the best support, find issues, make a plan to stop symptoms from returning and stick with treatment. […] Family-focused therapy. Family support and communication can help you stay with your treatment plan. It also can help you and your loved ones see and manage warning signs of mood swings.

• #46 5 Types of Supportive Bipolar Disorder Therapy

  https://www.healthline.com/health/bipolar-disorder/bipolar-disorder-supportive-therapy

  Research suggests that no matter what kind of therapy you use, psychoeducation learning about your disorder is very effective for bipolar disorder. […] Many therapists take a varied approach to psychotherapy, drawing techniques from different therapeutic approaches. […] CBT aims to help people recognize and change negative patterns of thinking and behavior that contribute to their symptoms. […] CBT for bipolar disorder may involve learning to identify triggers for mood episodes, developing coping strategies, and strengthening emotional regulation skills. […] A study from 2017 found that CBT treatment for bipolar disorder could improve mental and social well-being while reducing the severity of depressive symptoms and manic episodes. […] Many experts consider CBT the most supportive therapy type for bipolar disorder, but it’s not the only option.

• #47 5 Types of Supportive Bipolar Disorder Therapy

  https://www.healthline.com/health/bipolar-disorder/bipolar-disorder-supportive-therapy

  Research suggests that no matter what kind of therapy you use, psychoeducation learning about your disorder is very effective for bipolar disorder. […] Many therapists take a varied approach to psychotherapy, drawing techniques from different therapeutic approaches. […] CBT aims to help people recognize and change negative patterns of thinking and behavior that contribute to their symptoms. […] CBT for bipolar disorder may involve learning to identify triggers for mood episodes, developing coping strategies, and strengthening emotional regulation skills. […] A study from 2017 found that CBT treatment for bipolar disorder could improve mental and social well-being while reducing the severity of depressive symptoms and manic episodes. […] Many experts consider CBT the most supportive therapy type for bipolar disorder, but it’s not the only option.

• #48 Bipolar disorder – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/bipolar-disorder/diagnosis-treatment/drc-20355961

  Treatment is best guided by a medical doctor who diagnoses and treats mental health conditions (psychiatrist) who is skilled in treating bipolar and related disorders. Your care team also may include a psychologist, social worker or psychiatric nurse. […] Bipolar disorder is a lifelong condition, with treatment directed to manage symptoms. […] The main treatments for bipolar disorder include medicines and talk therapy, also known as psychotherapy, to control symptoms. Treatment also may include education and support groups. […] Talk therapy, also called psychotherapy, is a vital part of bipolar disorder treatment. This treatment can be provided in individual, family or group settings. […] Several types of therapy may help, including: Interpersonal and social rhythm therapy. This therapy focuses on stabilizing daily rhythms, including sleeping, waking and eating. A consistent routine helps manage moods. A daily routine for sleep, diet and exercise may help people with bipolar disorder.

• #49 Current and Emerging Therapies for Bipolar Disorder

  https://www.uspharmacist.com/article/current-and-emerging-therapies-for-bipolar-disorder

  Interpersonal and Social Rhythm Therapy (IPSRT) focuses on averting disease flares and/or prolonging the intervals between occurrences. IPSRT achieves this in BD patients by improving medication adherence, resolving stressful interpersonal situations, and reducing disruptions in social rhythms. Patients diagnosed with BD I who receive IPSRT live longer without a relapse and display more consistent social rhythms. […] Transcranial Magnetic Stimulation (TMS) is a noninvasive, brain-stimulating therapy for treatment-resistant depression approved by the FDA in 2008. TMS may be effective for treatment-resistant BD depressive episodes, as ~50% of treatment-resistant BD participants respond favorably to TMS treatment, with an additional ~25% partially responding. […] Emerging pharmacologic and nonpharmacologic treatment approaches that are more targeted show promise in terms of improved efficacy and tolerability and appear to be generally safe.

• #50 5 Types of Supportive Bipolar Disorder Therapy

  https://www.healthline.com/health/bipolar-disorder/bipolar-disorder-supportive-therapy

  A 2021 review found that family-focused or couple-focused therapies can help people with bipolar disorder by improving relationship dynamics. […] Interpersonal and social rhythm therapy (IPSRT) focuses on helping people with bipolar disorder regulate their daily routines. […] A 2020 study found that IPSRT reduces manic and depressive symptoms and improves functioning in people with bipolar disorders. […] Both the 2021 review and the 2019 review mentioned above agree on one thing: that psychoeducation is universally helpful for people with bipolar disorder. […] Psychoeducation can help you identify your triggers, feel less isolated, as you learn that other people face similar challenges, identify signs of a depressive or manic episode, find healthy, effective coping mechanisms, and learn about treatment and self-care strategies.

• #51 Bipolar disorder – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/bipolar-disorder/diagnosis-treatment/drc-20355961

  Cognitive behavioral therapy (CBT). This therapy focuses on identifying unhealthy, negative beliefs and behaviors and replacing them with healthy, positive beliefs and behaviors. CBT can help find what triggers your bipolar episodes. You also learn effective ways to manage stress and cope with upsetting situations. […] Psychoeducation. Learning about bipolar disorder, also known as psychoeducation, can help you and your loved ones know more about the condition. Knowing what’s going on can help you get the best support, find issues, make a plan to stop symptoms from returning and stick with treatment. […] Family-focused therapy. Family support and communication can help you stay with your treatment plan. It also can help you and your loved ones see and manage warning signs of mood swings.

• #52 5 Types of Supportive Bipolar Disorder Therapy

  https://www.healthline.com/health/bipolar-disorder/bipolar-disorder-supportive-therapy

  A 2019 review found that while CBT can be helpful, other kinds of therapy including family-focused therapy (FFT) and interpersonal and social rhythm therapy (IPSRT) may be more appropriate and effective for some people. […] DBT is a form of talk therapy that was originally developed to treat borderline personality disorder but has since been adapted to treat other mental health conditions, including bipolar disorder. […] The goal of DBT is to help people with bipolar disorder learn new skills for regulating emotions, improving relationships, and reducing impulsive behaviors. […] There’s an abundance of evidence showing that DBT can be effective for bipolar disorder. […] A 2023 review concluded that DBT improves symptoms of bipolar disorder. […] A 2016 review by the creator of FFT noted that, when combined with mood-stabilizing medications, FFT could reduce the length, frequency, and severity of mood episodes.

• #53 Bipolar disorder – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/bipolar-disorder/diagnosis-treatment/drc-20355961

  Cognitive behavioral therapy (CBT). This therapy focuses on identifying unhealthy, negative beliefs and behaviors and replacing them with healthy, positive beliefs and behaviors. CBT can help find what triggers your bipolar episodes. You also learn effective ways to manage stress and cope with upsetting situations. […] Psychoeducation. Learning about bipolar disorder, also known as psychoeducation, can help you and your loved ones know more about the condition. Knowing what’s going on can help you get the best support, find issues, make a plan to stop symptoms from returning and stick with treatment. […] Family-focused therapy. Family support and communication can help you stay with your treatment plan. It also can help you and your loved ones see and manage warning signs of mood swings.

• #54 5 Types of Supportive Bipolar Disorder Therapy

  https://www.healthline.com/health/bipolar-disorder/bipolar-disorder-supportive-therapy

  A 2021 review found that family-focused or couple-focused therapies can help people with bipolar disorder by improving relationship dynamics. […] Interpersonal and social rhythm therapy (IPSRT) focuses on helping people with bipolar disorder regulate their daily routines. […] A 2020 study found that IPSRT reduces manic and depressive symptoms and improves functioning in people with bipolar disorders. […] Both the 2021 review and the 2019 review mentioned above agree on one thing: that psychoeducation is universally helpful for people with bipolar disorder. […] Psychoeducation can help you identify your triggers, feel less isolated, as you learn that other people face similar challenges, identify signs of a depressive or manic episode, find healthy, effective coping mechanisms, and learn about treatment and self-care strategies.

• #55 Bipolar Disorder Treatment: Creating the Right Plan for You

  https://www.helpguide.org/mental-health/bipolar-disorder/bipolar-disorder-treatment

  In cognitive-behavioral therapy (CBT), you examine how your thoughts affect your emotions. You also learn how to change negative thinking patterns and behaviors into more positive ways of responding. […] Interpersonal therapy focuses on current relationship issues and helps you improve the way you relate to the important people in your life. […] Family-focused therapy addresses these issues and works to restore a healthy and supportive home environment. […] Dialectical behavior therapy (DBT) is a type of psychotherapy that is based on CBT principles. It emphasizes mindfulness, emotional regulation, interpersonal effectiveness, and distress toleranceall of which may help you cope with extreme emotions. […] Psychoeducation is an approach thats typically paired with other professional treatments. A mental health expert will provide you and your loved ones with information on the disorder, such as causes, symptoms, and coping methods.

• #56 5 Types of Supportive Bipolar Disorder Therapy

  https://www.healthline.com/health/bipolar-disorder/bipolar-disorder-supportive-therapy

  A 2019 review found that while CBT can be helpful, other kinds of therapy including family-focused therapy (FFT) and interpersonal and social rhythm therapy (IPSRT) may be more appropriate and effective for some people. […] DBT is a form of talk therapy that was originally developed to treat borderline personality disorder but has since been adapted to treat other mental health conditions, including bipolar disorder. […] The goal of DBT is to help people with bipolar disorder learn new skills for regulating emotions, improving relationships, and reducing impulsive behaviors. […] There’s an abundance of evidence showing that DBT can be effective for bipolar disorder. […] A 2023 review concluded that DBT improves symptoms of bipolar disorder. […] A 2016 review by the creator of FFT noted that, when combined with mood-stabilizing medications, FFT could reduce the length, frequency, and severity of mood episodes.

• #57 Therapy for Bipolar Disorder: Techniques and Efficacy

  https://www.verywellmind.com/therapy-for-bipolar-disorder-techniques-and-efficacy-6742122

  Therapy for bipolar disorder can help you decrease the severity of these symptoms. It can help you learn to identify and work to change the challenging thoughts, emotions, and behavioral patterns that accompany bipolar disorder. Moreover, it can offer both you and your family educational support and ongoing treatment guidance as you navigate the condition. […] Research has found some clear benefits to sticking to a care routine that includes both therapy and medication. In particular, therapy for bipolar disorder can do a few specific things to keep symptoms in check. […] According to Psychiatry Online, evidenced-based therapies for bipolar disorder may quicken the amount of time it takes for someone with bipolar disorder to go into remission. It can also help people learn the skills necessary to manage their symptoms and maintain healthy relationships.

• #58 Psychotherapy in Bipolar Depression: Effective Yet Underused

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10198128/

  Psychotherapy is an important part of managing bipolar depression and its associated impairments. There is considerable evidence that psychotherapies are effective adjuncts to pharmacotherapy in delaying or preventing episodes of bipolar depression. […] Psychotherapy can be a crucial part of managing bipolar disorder and is an important component of evidence-based outpatient treatment for this highly impairing chronic condition. […] In this article, we discuss the utility of psychotherapy as adjunctive to medications for bipolar depression and identify controversies. We explore why psychotherapy is helpful, its potential role in medication adherence, future directions to advance the field, and access to psychotherapeutic care. […] Adaptation of the chronic disease management model has been suggested, in which a combination of medications and psychotherapy is offered to optimize bipolar treatment.

• #59 Treatment of bipolar disorder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3876031/

  Treatment guidelines increasingly suggest that optimum management of bipolar disorder needs integration of pharmacotherapy with targeted psychotherapy. […] Evidence-based models of psychotherapy include cognitive-behavioural therapy, family-focused therapy, interpersonal and social rhythm therapy, group psychoeducation, and systematic care management. […] Most studies of psychotherapy for bipolar disorder are maintenance trials in which patients receive standard drugs and either an experimental psychosocial intervention or usual care. […] A meta-analysis of eight maintenance psychotherapy trials yielded effect sizes ranging from an odds ratio for reductions in any type of mood relapse to enhanced social functioning. […] Substantial progress has been made in the past decade in understanding of the role of psychotherapy in bipolar disorder. […] The next generation of psychotherapy studies will need to systematically assess mediators in the pathways from treatments to changes in illness course.

• #60 Bipolar Disorder: MedlinePlus

  https://medlineplus.gov/bipolardisorder.html

  Other treatment options include: […] Electroconvulsive therapy (ECT), a brain stimulation procedure that can help relieve symptoms. It uses a mild electric current and is done while you are under general anesthesia. ECT is most often used for severe bipolar disorder that is not getting better with other treatments. It may also be used when someone needs a treatment that will work more quickly than medicines. This might be when a person has a high risk of suicide or is catatonic (unresponsive). […] Repetitive transcranial magnetic stimulation (rTMS), a brain stimulation procedure that uses magnetic waves to relieve depression. It is not as powerful as ECT, but with rTMS, you don’t need general anesthesia. It also has a low risk of negative effects on your memory and thinking. […] Light therapy has been shown to be effective for seasonal affective disorder (SAD). Many people with bipolar disorder also find that their depression gets worse during certain seasons, usually in the fall and winter. Light therapy may help with their symptoms.

• #61 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  Several specific forms of psychotherapy have been shown to help speed recovery and improve functioning in bipolar disorder, including cognitive-behavioral therapy, interpersonal/social rhythm therapy, family therapy, and group therapy. […] Electroconvulsive therapy (ECT) is sometimes used for severely manic or depressed patients and for those who don’t respond to medication or for those women who, while pregnant, experience symptoms. […] The newer types of non-pharmacological treatments of depression are: VNS (Vagus or Vagal Nerve Stimulation) involves the implantation of a device that sends electrical signals to the vagus nerve in order to treat depression. […] TMS (Transcranial Magnetic Stimulation) is a procedure that involves the use of an electromagnetic coil to create electrical currents and stimulate nerve cells in the mood centers of the brain as a treatment for depression. […] Light therapy has proved effective as an additional treatment when bipolar disorder has a connection to seasonal affective disorder.

• #62 Bipolar disorder – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/bipolar-disorder/diagnosis-treatment/drc-20355961

  Depending on your needs, your health professional may add other treatments to your depression therapy, such as: Electroconvulsive therapy, also known as ECT. During ECT, electrical currents pass through the brain, causing a brief seizure. ECT seems to change brain chemistry, which can reverse symptoms of certain mental illnesses. ECT may be an option to treat bipolar disorder if you don’t get better with medicines, can’t take antidepressants for health reasons such as pregnancy or are at high risk of attempting suicide. […] Talk therapy. Initial and long-term therapy can help keep symptoms from returning. Talk therapy, also known as psychotherapy, can help children and teens manage their routines, cope better, handle learning difficulties, make social problems better, and make family bonds and communication stronger. […] Psychoeducation can include learning the symptoms of bipolar disorder and how they differ from behavior related to your child’s age, the situation and appropriate cultural behavior. Knowing more about bipolar disorder also can help you support your child.

• #63 Bipolar Disorders: Evaluation and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2021/0215/p227.html

  Monotherapy with antidepressants is contraindicated in patients with mixed features, manic episodes, or bipolar I disorder. […] High-quality evidence supports the use of lithium, lamotrigine (Lamictal), quetiapine, quetiapine in combination with lithium or valproic acid, aripiprazole (Abilify), and olanzapine (Zyprexa) for maintenance therapy in patients who have bipolar disorders. […] Electroconvulsive therapy is effective for mania and psychotic depression. […] Behavioral interventions, including basic psychoeducation and cognitive behavior therapy, are evidence-based adjuncts to pharmacotherapy that improve social function and reduce the need for medications, number of hospitalizations, and relapse rates.

• #64 Bipolar Disorders: Evaluation and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2021/0215/p227.html

  Monotherapy with antidepressants is contraindicated in patients with mixed features, manic episodes, or bipolar I disorder. […] High-quality evidence supports the use of lithium, lamotrigine (Lamictal), quetiapine, quetiapine in combination with lithium or valproic acid, aripiprazole (Abilify), and olanzapine (Zyprexa) for maintenance therapy in patients who have bipolar disorders. […] Electroconvulsive therapy is effective for mania and psychotic depression. […] Behavioral interventions, including basic psychoeducation and cognitive behavior therapy, are evidence-based adjuncts to pharmacotherapy that improve social function and reduce the need for medications, number of hospitalizations, and relapse rates.

• #65 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  Several specific forms of psychotherapy have been shown to help speed recovery and improve functioning in bipolar disorder, including cognitive-behavioral therapy, interpersonal/social rhythm therapy, family therapy, and group therapy. […] Electroconvulsive therapy (ECT) is sometimes used for severely manic or depressed patients and for those who don’t respond to medication or for those women who, while pregnant, experience symptoms. […] The newer types of non-pharmacological treatments of depression are: VNS (Vagus or Vagal Nerve Stimulation) involves the implantation of a device that sends electrical signals to the vagus nerve in order to treat depression. […] TMS (Transcranial Magnetic Stimulation) is a procedure that involves the use of an electromagnetic coil to create electrical currents and stimulate nerve cells in the mood centers of the brain as a treatment for depression. […] Light therapy has proved effective as an additional treatment when bipolar disorder has a connection to seasonal affective disorder.

• #66 Current and Emerging Therapies for Bipolar Disorder

  https://www.uspharmacist.com/article/current-and-emerging-therapies-for-bipolar-disorder

  Interpersonal and Social Rhythm Therapy (IPSRT) focuses on averting disease flares and/or prolonging the intervals between occurrences. IPSRT achieves this in BD patients by improving medication adherence, resolving stressful interpersonal situations, and reducing disruptions in social rhythms. Patients diagnosed with BD I who receive IPSRT live longer without a relapse and display more consistent social rhythms. […] Transcranial Magnetic Stimulation (TMS) is a noninvasive, brain-stimulating therapy for treatment-resistant depression approved by the FDA in 2008. TMS may be effective for treatment-resistant BD depressive episodes, as ~50% of treatment-resistant BD participants respond favorably to TMS treatment, with an additional ~25% partially responding. […] Emerging pharmacologic and nonpharmacologic treatment approaches that are more targeted show promise in terms of improved efficacy and tolerability and appear to be generally safe.

• #67 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  Several specific forms of psychotherapy have been shown to help speed recovery and improve functioning in bipolar disorder, including cognitive-behavioral therapy, interpersonal/social rhythm therapy, family therapy, and group therapy. […] Electroconvulsive therapy (ECT) is sometimes used for severely manic or depressed patients and for those who don’t respond to medication or for those women who, while pregnant, experience symptoms. […] The newer types of non-pharmacological treatments of depression are: VNS (Vagus or Vagal Nerve Stimulation) involves the implantation of a device that sends electrical signals to the vagus nerve in order to treat depression. […] TMS (Transcranial Magnetic Stimulation) is a procedure that involves the use of an electromagnetic coil to create electrical currents and stimulate nerve cells in the mood centers of the brain as a treatment for depression. […] Light therapy has proved effective as an additional treatment when bipolar disorder has a connection to seasonal affective disorder.

• #68 Assessing Treatment for Bipolar Disorder | Treatment Assessment Guide

  https://www.healthline.com/health/bipolar-disorder/bipolar-treatment-assessment

  A doctor will often prescribe one medication to see whether it works. Depending on your symptoms, they may prescribe a combination of medications. […] A doctor may prescribe an antipsychotic medication if you’re experiencing acute manic episodes that require hospitalization. However, mood stabilizers, such as lithium, are generally considered the main therapy for bipolar disorder. […] According to the National Alliance on Mental Illness, these are some of the most common therapy options to treat bipolar disorder: Family-focused therapy, Interpersonal and social rhythm therapy, Cognitive behavioral therapy, Dialectical behavioral therapy, Support groups. […] Some lifestyle habits may be helpful for managing bipolar disorder symptoms. These include: keeping a consistent sleep schedule, adopting a healthy diet, finding ways to reduce or manage stress, getting regular exercise, maintaining a support network of family and friends, keeping a mood journal, avoiding alcohol and other drugs. […] If you’re experiencing unpleasant side effects or you feel like a certain medication isn’t working properly, talk with your doctor. They may be able to help you find a treatment that works for you.

• #69 Bipolar Disorder Treatment: Medications and Therapy

  https://psychcentral.com/bipolar/bipolar-disorder-treatment

  Research has shown that psychoeducation is effective in managing long-term symptoms of bipolar disorder. Its typically recommended as a first-line treatment, especially when youre first diagnosed. […] CBT techniques can help you rethink the way you think (seriously), so you can recognize thoughts that serve you well and let go of negative or destructive thinking. […] FFT is typically seen as a second-line treatment for bipolar depression. […] Research indicates that IPSRT may help people with bipolar disorder to reduce their mania and depression symptoms. […] Ongoing research supports DBT for treating bipolar disorder, especially with medication. […] If youre looking for more ways to manage everyday symptoms, theres a lot you can do. […] Make it easy to take your medication by setting up a routine.

• #70 Integrative Therapies for Bipolar Disorder

  https://www.everydayhealth.com/bipolar-disorder/alternative-treatments-for-bipolar-disorder.aspx

  Unpredictable mood episodes can be challenging to manage for someone with bipolar disorder a mental health condition that causes emotional highs (mania) and lows (depression). And while medication and psychotherapy are the gold standard for alleviating symptoms, many people like to explore complementary and integrative therapies, too. […] Many complementary and integrative therapies for bipolar disorder may help depressive symptoms, some of them can actually worsen manic symptoms, says Blake Gibson, MD, a psychiatrist at the University of Pittsburgh Medical Center (UPMC) Western Psychiatric Hospital. […] Regular exercise can benefit both your mood and your physical health. […] Yoga can be a helpful way for people with bipolar disorder to manage stress, improve their sleep, and alleviate depressive symptoms.

• #71 Integrative Therapies for Bipolar Disorder

  https://www.everydayhealth.com/bipolar-disorder/alternative-treatments-for-bipolar-disorder.aspx

  Omega-3 fatty acids may improve symptoms of bipolar depression. […] Probiotics may have a positive effect on people with bipolar disorder, but more studies are needed to determine their role in a bipolar disorder treatment plan. […] Meditation may help people with bipolar disorder lessen their depressive symptoms and feel better. […] Bright light therapy could help people with bipolar disorder manage symptoms of depression. […] Rhodiola should be avoided by people with bipolar depression. […] Doctors generally don’t recommend SAMe for bipolar disorder because it can induce mania. […] Most doctors don’t recommend St. John’s wort for bipolar disorder because of potential drug interactions, side effects, and worsened symptoms.

• #72 Bipolar Disorder Treatment

  https://www.webmd.com/bipolar-disorder/understanding-bipolar-disorder-treatment

  Several specific forms of psychotherapy have been shown to help speed recovery and improve functioning in bipolar disorder, including cognitive-behavioral therapy, interpersonal/social rhythm therapy, family therapy, and group therapy. […] Electroconvulsive therapy (ECT) is sometimes used for severely manic or depressed patients and for those who don’t respond to medication or for those women who, while pregnant, experience symptoms. […] The newer types of non-pharmacological treatments of depression are: VNS (Vagus or Vagal Nerve Stimulation) involves the implantation of a device that sends electrical signals to the vagus nerve in order to treat depression. […] TMS (Transcranial Magnetic Stimulation) is a procedure that involves the use of an electromagnetic coil to create electrical currents and stimulate nerve cells in the mood centers of the brain as a treatment for depression. […] Light therapy has proved effective as an additional treatment when bipolar disorder has a connection to seasonal affective disorder.

• #73 Integrative Therapies for Bipolar Disorder

  https://www.everydayhealth.com/bipolar-disorder/alternative-treatments-for-bipolar-disorder.aspx

  Omega-3 fatty acids may improve symptoms of bipolar depression. […] Probiotics may have a positive effect on people with bipolar disorder, but more studies are needed to determine their role in a bipolar disorder treatment plan. […] Meditation may help people with bipolar disorder lessen their depressive symptoms and feel better. […] Bright light therapy could help people with bipolar disorder manage symptoms of depression. […] Rhodiola should be avoided by people with bipolar depression. […] Doctors generally don’t recommend SAMe for bipolar disorder because it can induce mania. […] Most doctors don’t recommend St. John’s wort for bipolar disorder because of potential drug interactions, side effects, and worsened symptoms.

• #74 Integrative Therapies for Bipolar Disorder

  https://www.everydayhealth.com/bipolar-disorder/alternative-treatments-for-bipolar-disorder.aspx

  Omega-3 fatty acids may improve symptoms of bipolar depression. […] Probiotics may have a positive effect on people with bipolar disorder, but more studies are needed to determine their role in a bipolar disorder treatment plan. […] Meditation may help people with bipolar disorder lessen their depressive symptoms and feel better. […] Bright light therapy could help people with bipolar disorder manage symptoms of depression. […] Rhodiola should be avoided by people with bipolar depression. […] Doctors generally don’t recommend SAMe for bipolar disorder because it can induce mania. […] Most doctors don’t recommend St. John’s wort for bipolar disorder because of potential drug interactions, side effects, and worsened symptoms.

• #75 Integrative Therapies for Bipolar Disorder

  https://www.everydayhealth.com/bipolar-disorder/alternative-treatments-for-bipolar-disorder.aspx

  Omega-3 fatty acids may improve symptoms of bipolar depression. […] Probiotics may have a positive effect on people with bipolar disorder, but more studies are needed to determine their role in a bipolar disorder treatment plan. […] Meditation may help people with bipolar disorder lessen their depressive symptoms and feel better. […] Bright light therapy could help people with bipolar disorder manage symptoms of depression. […] Rhodiola should be avoided by people with bipolar depression. […] Doctors generally don’t recommend SAMe for bipolar disorder because it can induce mania. […] Most doctors don’t recommend St. John’s wort for bipolar disorder because of potential drug interactions, side effects, and worsened symptoms.

• #76 Integrative Therapies for Bipolar Disorder

  https://www.everydayhealth.com/bipolar-disorder/alternative-treatments-for-bipolar-disorder.aspx

  Omega-3 fatty acids may improve symptoms of bipolar depression. […] Probiotics may have a positive effect on people with bipolar disorder, but more studies are needed to determine their role in a bipolar disorder treatment plan. […] Meditation may help people with bipolar disorder lessen their depressive symptoms and feel better. […] Bright light therapy could help people with bipolar disorder manage symptoms of depression. […] Rhodiola should be avoided by people with bipolar depression. […] Doctors generally don’t recommend SAMe for bipolar disorder because it can induce mania. […] Most doctors don’t recommend St. John’s wort for bipolar disorder because of potential drug interactions, side effects, and worsened symptoms.

• #77

  https://www.who.int/news-room/fact-sheets/detail/bipolar-disorder

  Mood stabilizers (such as lithium, valproate) and antipsychotics are proven to help manage acute mania. […] Antidepressants should not be taken during a manic episode and they may be combined with mood stabilizers or antipsychotics during episodes of depression. […] Adults with bipolar disorder who are in complete remission (no symptoms) usually need to continue with mood stabilizers or antipsychotic medicines for at least six months. Those experiencing multiple episodes of mania and depression will usually require longer-term treatment to minimize relapses. […] Psychological interventions (e.g. cognitive behavioural therapy, interpersonal therapy, psychoeducation) can effectively reduce depressive symptoms and the possibility of them coming back. […] Recovery-oriented psychosocial interventions include supported employment, supported housing, peer support, and social and life skills training. They serve to promote hope and to support the autonomy, personal empowerment and social inclusion of people with bipolar disorder. […] Medicines and psychological or psychosocial interventions should be tailored to the needs of the person and combined for best outcomes.

• #78 Treatment of bipolar disorder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3876031/

  Treatment guidelines increasingly suggest that optimum management of bipolar disorder needs integration of pharmacotherapy with targeted psychotherapy. […] Evidence-based models of psychotherapy include cognitive-behavioural therapy, family-focused therapy, interpersonal and social rhythm therapy, group psychoeducation, and systematic care management. […] Most studies of psychotherapy for bipolar disorder are maintenance trials in which patients receive standard drugs and either an experimental psychosocial intervention or usual care. […] A meta-analysis of eight maintenance psychotherapy trials yielded effect sizes ranging from an odds ratio for reductions in any type of mood relapse to enhanced social functioning. […] Substantial progress has been made in the past decade in understanding of the role of psychotherapy in bipolar disorder. […] The next generation of psychotherapy studies will need to systematically assess mediators in the pathways from treatments to changes in illness course.

• #79 Treatment of bipolar disorder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3876031/

  Treatment guidelines increasingly suggest that optimum management of bipolar disorder needs integration of pharmacotherapy with targeted psychotherapy. […] Evidence-based models of psychotherapy include cognitive-behavioural therapy, family-focused therapy, interpersonal and social rhythm therapy, group psychoeducation, and systematic care management. […] Most studies of psychotherapy for bipolar disorder are maintenance trials in which patients receive standard drugs and either an experimental psychosocial intervention or usual care. […] A meta-analysis of eight maintenance psychotherapy trials yielded effect sizes ranging from an odds ratio for reductions in any type of mood relapse to enhanced social functioning. […] Substantial progress has been made in the past decade in understanding of the role of psychotherapy in bipolar disorder. […] The next generation of psychotherapy studies will need to systematically assess mediators in the pathways from treatments to changes in illness course.

• #80 Treatment of bipolar disorder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3876031/

  Treatment guidelines increasingly suggest that optimum management of bipolar disorder needs integration of pharmacotherapy with targeted psychotherapy. […] Evidence-based models of psychotherapy include cognitive-behavioural therapy, family-focused therapy, interpersonal and social rhythm therapy, group psychoeducation, and systematic care management. […] Most studies of psychotherapy for bipolar disorder are maintenance trials in which patients receive standard drugs and either an experimental psychosocial intervention or usual care. […] A meta-analysis of eight maintenance psychotherapy trials yielded effect sizes ranging from an odds ratio for reductions in any type of mood relapse to enhanced social functioning. […] Substantial progress has been made in the past decade in understanding of the role of psychotherapy in bipolar disorder. […] The next generation of psychotherapy studies will need to systematically assess mediators in the pathways from treatments to changes in illness course.

• #81 Psychotherapy in Bipolar Depression: Effective Yet Underused

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10198128/

  Psychotherapy is an important part of managing bipolar depression and its associated impairments. There is considerable evidence that psychotherapies are effective adjuncts to pharmacotherapy in delaying or preventing episodes of bipolar depression. […] Psychotherapy can be a crucial part of managing bipolar disorder and is an important component of evidence-based outpatient treatment for this highly impairing chronic condition. […] In this article, we discuss the utility of psychotherapy as adjunctive to medications for bipolar depression and identify controversies. We explore why psychotherapy is helpful, its potential role in medication adherence, future directions to advance the field, and access to psychotherapeutic care. […] Adaptation of the chronic disease management model has been suggested, in which a combination of medications and psychotherapy is offered to optimize bipolar treatment.

• #82 Bipolar Disorder Treatment | Exploring Cutting-Edge Technologies

  https://www.animosanopsychiatry.com/advancements-in-bipolar-disorder-treatment/

  Bipolar disorder, a mental health condition marked by extreme mood swings and changes in energy, is a challenging reality for many. […] While current treatments like medication and counseling have provided relief for many, research continues to aim for more advanced and targeted interventions. […] Data from various studies suggest that these digital platforms can minimize depressive symptoms and enhance the lives of those living with bipolar disorder. […] Research shows that combining CBT with medication can indeed make a difference in managing the symptoms of bipolar disorder. […] Some initial research has shown promising results, hinting at a potential reduction in manic and depressive symptoms. […] Scientists speculate that changing a persons diet or introducing certain probiotics could prove valuable in managing bipolar symptoms, although this is still a developing area of research.

• #83 Assessing Treatment for Bipolar Disorder | Treatment Assessment Guide

  https://www.healthline.com/health/bipolar-disorder/bipolar-treatment-assessment

  Bipolar disorder is a treatable condition. Most people manage it with a combination of medication, talk therapy, and lifestyle strategies. […] Treatment varies from person to person because bipolar disorder has several subtypes. […] If you have a bipolar disorder diagnosis, a doctor might recommend an initial treatment. If that treatment does not meet your goals, you can work with your doctor to find a new option. […] Once you receive a bipolar disorder diagnosis, a healthcare professional will recommend a treatment plan that might work for you. Options include: medication, therapy, lifestyle strategies, electroconvulsive therapy (ECT). […] Medication is the first-line treatment for all types of bipolar disorder. It is often combined with talk therapy to help people learn about their condition and stay on a treatment plan.

• #84 Bipolar Disorder Treatment | Hazelden Betty Ford

  https://www.hazeldenbettyford.org/mental-health-services/bipolar-disorder

  All forms of bipolar disorder are very treatable. […] The most-effective approach involves a treatment plan tailored to meet the individual patient’s specific needs and circumstances. Antidepressants and other medications along with psychotherapy (talk therapy) are often used to manage symptoms. […] Finding the most beneficial medication can be challenging because medication response varies from person to person. […] Most people with bipolar disorder are prescribed more than one medication. […] Ongoing treatment and consistent, continuous use of medications is recommended. […] Cognitive behavioral therapy is often recommended as a treatment option. […] A cognitive-behavioral psychotherapy approach helps patients replace negative thoughts, beliefs and behaviors with more useful and positive ones. […] Healthy habits such as sticking to a regular routine, getting enough sleep, exercising regularly and maintaining a healthy diet are helpful in managing symptoms.

• #85 Bipolar Disorder (Manic Depression): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/9294-bipolar-disorder

  Certain medications can help manage symptoms of bipolar disorder. You may need to try several different medications, with guidance from your healthcare provider, before finding what works best. […] Medications healthcare providers generally prescribe to treat bipolar disorder include: Mood stabilizers, Second-generation (atypical) neuroleptics (also called antipsychotics), Antidepressants. […] Healthcare providers often prescribe second-generation or atypical neuroleptics (antipsychotics) in combination with a mood stabilizer for people with bipolar disorder. […] Healthcare providers sometimes prescribe antidepressant medication to treat depressive episodes in bipolar disorder, combining the antidepressant with a mood stabilizer to prevent triggering a manic episode. […] Other treatment options your healthcare provider may consider for treating bipolar disorder include: Electroconvulsive therapy (ECT), Transcranial magnetic stimulation (TMS), Thyroid medications, Ketamine treatment, Hospitalization. […] Your healthcare team will likely recommend making lifestyle changes to stop patterns of behavior that worsen the symptoms of bipolar disorder.

• #86 5 Types of Supportive Bipolar Disorder Therapy

  https://www.healthline.com/health/bipolar-disorder/bipolar-disorder-supportive-therapy

  Research suggests that no matter what kind of therapy you use, psychoeducation learning about your disorder is very effective for bipolar disorder. […] Many therapists take a varied approach to psychotherapy, drawing techniques from different therapeutic approaches. […] CBT aims to help people recognize and change negative patterns of thinking and behavior that contribute to their symptoms. […] CBT for bipolar disorder may involve learning to identify triggers for mood episodes, developing coping strategies, and strengthening emotional regulation skills. […] A study from 2017 found that CBT treatment for bipolar disorder could improve mental and social well-being while reducing the severity of depressive symptoms and manic episodes. […] Many experts consider CBT the most supportive therapy type for bipolar disorder, but it’s not the only option.

• #87 5 Types of Supportive Bipolar Disorder Therapy

  https://www.healthline.com/health/bipolar-disorder/bipolar-disorder-supportive-therapy

  A 2019 review found that while CBT can be helpful, other kinds of therapy including family-focused therapy (FFT) and interpersonal and social rhythm therapy (IPSRT) may be more appropriate and effective for some people. […] DBT is a form of talk therapy that was originally developed to treat borderline personality disorder but has since been adapted to treat other mental health conditions, including bipolar disorder. […] The goal of DBT is to help people with bipolar disorder learn new skills for regulating emotions, improving relationships, and reducing impulsive behaviors. […] There’s an abundance of evidence showing that DBT can be effective for bipolar disorder. […] A 2023 review concluded that DBT improves symptoms of bipolar disorder. […] A 2016 review by the creator of FFT noted that, when combined with mood-stabilizing medications, FFT could reduce the length, frequency, and severity of mood episodes.

• #88 Bipolar disorder – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/bipolar-disorder/diagnosis-treatment/drc-20355961

  Treatment is best guided by a medical doctor who diagnoses and treats mental health conditions (psychiatrist) who is skilled in treating bipolar and related disorders. Your care team also may include a psychologist, social worker or psychiatric nurse. […] Bipolar disorder is a lifelong condition, with treatment directed to manage symptoms. […] The main treatments for bipolar disorder include medicines and talk therapy, also known as psychotherapy, to control symptoms. Treatment also may include education and support groups. […] Talk therapy, also called psychotherapy, is a vital part of bipolar disorder treatment. This treatment can be provided in individual, family or group settings. […] Several types of therapy may help, including: Interpersonal and social rhythm therapy. This therapy focuses on stabilizing daily rhythms, including sleeping, waking and eating. A consistent routine helps manage moods. A daily routine for sleep, diet and exercise may help people with bipolar disorder.

• #89 Bipolar disorder – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/bipolar-disorder/diagnosis-treatment/drc-20355961

  Treatment is best guided by a medical doctor who diagnoses and treats mental health conditions (psychiatrist) who is skilled in treating bipolar and related disorders. Your care team also may include a psychologist, social worker or psychiatric nurse. […] Bipolar disorder is a lifelong condition, with treatment directed to manage symptoms. […] The main treatments for bipolar disorder include medicines and talk therapy, also known as psychotherapy, to control symptoms. Treatment also may include education and support groups. […] Talk therapy, also called psychotherapy, is a vital part of bipolar disorder treatment. This treatment can be provided in individual, family or group settings. […] Several types of therapy may help, including: Interpersonal and social rhythm therapy. This therapy focuses on stabilizing daily rhythms, including sleeping, waking and eating. A consistent routine helps manage moods. A daily routine for sleep, diet and exercise may help people with bipolar disorder.

• #90

  https://www.who.int/news-room/fact-sheets/detail/bipolar-disorder

  Mood stabilizers (such as lithium, valproate) and antipsychotics are proven to help manage acute mania. […] Antidepressants should not be taken during a manic episode and they may be combined with mood stabilizers or antipsychotics during episodes of depression. […] Adults with bipolar disorder who are in complete remission (no symptoms) usually need to continue with mood stabilizers or antipsychotic medicines for at least six months. Those experiencing multiple episodes of mania and depression will usually require longer-term treatment to minimize relapses. […] Psychological interventions (e.g. cognitive behavioural therapy, interpersonal therapy, psychoeducation) can effectively reduce depressive symptoms and the possibility of them coming back. […] Recovery-oriented psychosocial interventions include supported employment, supported housing, peer support, and social and life skills training. They serve to promote hope and to support the autonomy, personal empowerment and social inclusion of people with bipolar disorder. […] Medicines and psychological or psychosocial interventions should be tailored to the needs of the person and combined for best outcomes.

• #91 Medicines for bipolar disorder | healthdirect

  https://www.healthdirect.gov.au/medicines-for-bipolar-disorder

  Never stop your medicine or adjust doses on your own without talking to your doctor. […] Medicines used for bipolar disorder can cause side effects in some people. […] You should see your doctor if you are experiencing ongoing symptoms of bipolar disorder despite treatment. […] You should also see your doctor if you are experiencing side effects. […] For most people, the benefits of treatment outweigh the risks of being on medicine.

• #92 Medicines for bipolar disorder | healthdirect

  https://www.healthdirect.gov.au/medicines-for-bipolar-disorder

  Medicines play a vital role and are used to treat episodes of depression, treat episodes of mania or hypomania, and reduce the chance of these episodes from happening again. […] Long-term treatment of bipolar disorder also includes lifestyle changes such as regular exercise, maintaining a stable sleep schedule, maintaining a healthy diet, ensuring adequate social support from your family, friends, and getting support from a bipolar disorder support group, if available. […] People with bipolar disorder often need to take a combination of medicines. […] You and your doctor will work out which medicines work best for you. […] It’s important to talk to your doctor and work with them to find the right one/s, and to take them as prescribed. […] Bipolar disorder is a long-term (chronic) condition. Most people will take medicines for bipolar disorder for years.

• #93 Is bipolar disorder curable? Treatment and long-term management

  https://www.medicalnewstoday.com/articles/324349

  A doctor cannot offer a cure for bipolar disorder, but they can support a person with the condition to manage their symptoms. […] Effective, consistent treatment can reduce the frequency and severity of mood episodes. […] Bipolar disorder is a long-term mental health condition that affects a persons mood. It does not currently have a cure, but treatment can reduce the number or frequency of mood shifts. […] With treatment, a person with bipolar disorder may have extended periods without severe mood episodes, during which they may experience few or no symptoms. […] Continuing to engage with treatment and self-care is the best way to reduce the effects.

• #94

  https://www.who.int/news-room/fact-sheets/detail/bipolar-disorder

  Even though symptoms often recur, recovery is possible. With appropriate care, people with bipolar disorder can cope with their symptoms and live meaningful and productive lives. […] There are a range of effective treatment options, typically a mix of medicines and psychological and psychosocial interventions. Medicines are considered essential for treatment, but themselves are usually insufficient to achieve full recovery. People with bipolar disorder should be treated with respect and dignity and should be meaningfully involved in care choices, including through shared decision-making regarding treatment and care, balancing effectiveness, side-effects and individual preferences. […] People with bipolar disorder need treatment and care across acute episodes of mania and depression and when indicated, longer-term treatment to prevent relapse.

• #95 Treatment of bipolar disorder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3876031/

  Treatment of bipolar disorder conventionally focuses on acute stabilisation, in which the goal is to bring a patient with mania or depression to a symptomatic recovery with euthymic (stable) mood; and on maintenance, in which the goals are relapse prevention, reduction of subthreshold symptoms, and enhanced social and occupational functioning. […] Treatment of both phases of the illness can be complex, because the same treatments that alleviate depression can cause mania, hypomania, or rapid cycling (defined as four or more episodes in 12 months), and the treatments that reduce mania might cause rebound depressive episodes. […] We focus on contemporary issues in the acute and maintenance treatment of bipolar disorder. […] Despite a substantial expansion of research into bipolar disorder and potential treatments during the past 2 decades, true advances have been few. The development of effective treatments for bipolar disorder is hampered by our scarce knowledge of basic disease mechanisms and the consequent absence of validated pharmacological targets, and unconvincing animal or human experimental drug models. […] Most newly introduced treatments for bipolar disorder, whether pharmacological or psychological, have been based on an extension of use from another disorder, eg, antipsychotics in mania and antidepressants or cognitive-behavioural therapy for bipolar depression.

• #96 Treatment of bipolar disorder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3876031/

  We review recent developments in the acute and long-term treatment of bipolar disorder and identify promising future routes to therapeutic innovation. Overall, advances in drug treatment remain quite modest. Antipsychotic drugs are effective in the acute treatment of mania; their efficacy in the treatment of depression is variable with the clearest evidence for quetiapine. […] Despite their widespread use, considerable uncertainty and controversy remains about the use of antidepressant drugs in the management of depressive episodes. Lithium has the strongest evidence for long-term relapse prevention; the evidence for anticonvulsants such as divalproex and lamotrigine is less robust and there is much uncertainty about the longer term benefits of antipsychotics. Substantial progress has been made in the development and assessment of adjunctive psychosocial interventions. Long-term maintenance and possibly acute stabilisation of depression can be enhanced by the combination of psychosocial treatments with drugs. […] The development of future treatments should consider both the neurobiological and psychosocial mechanisms underlying the disorder. We should continue to repurpose treatments and to recognise the role of serendipity. We should also investigate optimum combinations of pharmacological and psychotherapeutic treatments at different stages of the illness. […] To be economically viable, existing psychotherapy protocols need to be made briefer and more efficient for improved scalability and sustainability in widespread implementation.

• #97 Management of Bipolar Disorder | AAFP

  https://www.aafp.org/pubs/afp/issues/2000/0915/p1343.html

  Medication is the key to stabilizing bipolar disorder. Initial treatment of mania consists of lithium or valproic acid (Depakene). […] When the patient with bipolar disorder becomes depressed, a selective serotonin reuptake inhibitor (SSRI) or bupropion (Wellbutrin) is recommended. […] Treatment with mood stabilizers requires periodic laboratory tests to monitor the patient’s response to the drug. […] Family members must be educated about possible relapses, what to look for and how to handle different situations. […] Bipolar disorder can be well managed by family physicians in concert with psychiatrists.

• #98 Medications for Treatment of Bipolar Disorders – Psychiatric Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/psychiatric-disorders/mood-disorders/medications-for-treatment-of-bipolar-disorders

  Choice of pharmacologic agents to treat bipolar disorders can be difficult because all medications can potentially have significant adverse effects, drug interactions are common, and no medication is universally effective. Selection should be based on what has previously been effective and well-tolerated in a given patient. […] For severe manic psychosis, in which immediate patient safety and management is compromised, urgent behavioral control usually requires a sedating second-generation antipsychotic, sometimes supplemented initially with a benzodiazepine such as lorazepam or clonazepam. […] For less severe acute episodes in patients without contraindications (eg, renal disorders), lithium is a good first choice for both mania and depressive episodes. […] For bipolar depression, the best evidence suggests using quetiapine, cariprazine, lumateperone, or lurasidone alone or the combination of fluoxetine and olanzapine.

• #99 Available Bipolar Disorder Treatments to Consider

  https://www.verywellhealth.com/bipolar-disorder-treatments-8425817

  Electroconvulsive therapy (ECT) can help manage severe cases of acute mania, mixed episodes, and bipolar depression. […] Light therapy involves sitting in front of a light box daily to help reset circadian rhythms and regulate neurotransmitters. […] Repetitive transcranial magnetic stimulation (rTMS) is a treatment for depression in which a qualified healthcare provider uses magnetic waves to stimulate the brain. It can be helpful in the depressive phase of bipolar disorder and has a lower risk of side effects than ECT. […] Usually, healthcare providers prescribe one or more medications, such as lithium, in combination with psychotherapy for long-term bipolar disorder management. […] Treatment for a manic episode can involve: Temporary medication change to reduce symptoms of psychosis, agitation, and mania, Treatment in a residential or inpatient mental health facility, Education in mood charting and journaling after the acute episode to prevent and identify future manic episodes.

• #100 Treatment of bipolar disorder

  https://pmc.ncbi.nlm.nih.gov/articles/PMC3876031/

  The treatment of bipolar depression is a major challenge, with few treatments of proven efficacy and, in particular, substantial controversy about the role of antidepressant drugs. […] A recent updated meta-analysis of antidepressants in bipolar depression reported a pooled effect no different from placebo with statistically significant heterogeneity. […] Therefore, to conclude that no antidepressant agent is effective in bipolar depression is probably premature, although the emerging evidence suggests that paroxetine is ineffective. […] Lithium, introduced by John Cade in 1949, remains the best established long-term treatment for bipolar disorder. […] A meta-analysis of five placebo-controlled lithium maintenance trials showed that lithium reduces the risk of manic relapses by 38% and depressive relapse by 28%. […] However, the benefits of lithium are restricted by adverse effects and a low therapeutic index.

• #101 Management of Bipolar Disorder | AAFP

  https://www.aafp.org/pubs/afp/issues/2000/0915/p1343.html

  Medication is the key to stabilizing bipolar disorder. Initial treatment of mania consists of lithium or valproic acid (Depakene). […] When the patient with bipolar disorder becomes depressed, a selective serotonin reuptake inhibitor (SSRI) or bupropion (Wellbutrin) is recommended. […] Treatment with mood stabilizers requires periodic laboratory tests to monitor the patient’s response to the drug. […] Family members must be educated about possible relapses, what to look for and how to handle different situations. […] Bipolar disorder can be well managed by family physicians in concert with psychiatrists.

• #102

  https://www2.hse.ie/conditions/bipolar-disorder/treatment/

  If you are given antidepressants, these are often used alongside a mood stabiliser. […] Lithium is the medicine most commonly used to treat bipolar disorder. […] It is a long-term method of treatment for episodes of mania, hypomania (less severe mania) and depression. […] Anticonvulsant medicines are often used to treat epilepsy. But they’re also effective in treating bipolar disorder. […] Antipsychotic medicines are sometimes prescribed to treat episodes of mania or hypomania. […] They may also be used as a long-term mood stabiliser. […] Some people find psychological treatment helpful. […] Talking with a trained therapist is an important part of treatment for bipolar disorder. […] Psychological treatment usually consists of around 16 sessions. […] Lifestyle advice can include information about: regular exercise, planning activities you enjoy that give you a sense of achievement, improving your diet, getting more sleep. […] You can learn to recognise the warning signs of an episode of mania or depression. […] Wellness Recovery Action Plans (WRAP) are very useful.

• #103

  https://www.who.int/news-room/fact-sheets/detail/bipolar-disorder

  Mood stabilizers (such as lithium, valproate) and antipsychotics are proven to help manage acute mania. […] Antidepressants should not be taken during a manic episode and they may be combined with mood stabilizers or antipsychotics during episodes of depression. […] Adults with bipolar disorder who are in complete remission (no symptoms) usually need to continue with mood stabilizers or antipsychotic medicines for at least six months. Those experiencing multiple episodes of mania and depression will usually require longer-term treatment to minimize relapses. […] Psychological interventions (e.g. cognitive behavioural therapy, interpersonal therapy, psychoeducation) can effectively reduce depressive symptoms and the possibility of them coming back. […] Recovery-oriented psychosocial interventions include supported employment, supported housing, peer support, and social and life skills training. They serve to promote hope and to support the autonomy, personal empowerment and social inclusion of people with bipolar disorder. […] Medicines and psychological or psychosocial interventions should be tailored to the needs of the person and combined for best outcomes.

• #104 Medications for Treatment of Bipolar Disorders – Psychiatric Disorders – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/psychiatric-disorders/mood-disorders/medications-for-treatment-of-bipolar-disorders

  Choice of pharmacologic agents to treat bipolar disorders can be difficult because all medications can potentially have significant adverse effects, drug interactions are common, and no medication is universally effective. Selection should be based on what has previously been effective and well-tolerated in a given patient. […] For severe manic psychosis, in which immediate patient safety and management is compromised, urgent behavioral control usually requires a sedating second-generation antipsychotic, sometimes supplemented initially with a benzodiazepine such as lorazepam or clonazepam. […] For less severe acute episodes in patients without contraindications (eg, renal disorders), lithium is a good first choice for both mania and depressive episodes. […] For bipolar depression, the best evidence suggests using quetiapine, cariprazine, lumateperone, or lurasidone alone or the combination of fluoxetine and olanzapine.

• #105 Bipolar disorder in adults: Choosing maintenance treatment – UpToDate

  https://www.uptodate.com/contents/bipolar-disorder-in-adults-choosing-maintenance-treatment

  Bipolar disorder in adults: Choosing maintenance treatment […] Following remission of a bipolar mood episode, nearly all patients require maintenance treatment to delay or prevent another episode. Standard maintenance treatment consists of pharmacotherapy plus adjunctive psychotherapy. However, if psychotherapy is not available or is declined, pharmacotherapy alone is reasonable. […] Selecting maintenance treatment for bipolar disorder is reviewed here. The use of adjunctive psychotherapy for maintenance treatment of bipolar disorder; management of poor adherence to maintenance pharmacotherapy; pharmacotherapy for acute bipolar mood episodes; teratogenic risks and neonatal issues involved in pharmacotherapy; and the epidemiology, clinical manifestations, and diagnosis of bipolar disorder are discussed separately.

• #106

  https://www.who.int/news-room/fact-sheets/detail/bipolar-disorder

  Mood stabilizers (such as lithium, valproate) and antipsychotics are proven to help manage acute mania. […] Antidepressants should not be taken during a manic episode and they may be combined with mood stabilizers or antipsychotics during episodes of depression. […] Adults with bipolar disorder who are in complete remission (no symptoms) usually need to continue with mood stabilizers or antipsychotic medicines for at least six months. Those experiencing multiple episodes of mania and depression will usually require longer-term treatment to minimize relapses. […] Psychological interventions (e.g. cognitive behavioural therapy, interpersonal therapy, psychoeducation) can effectively reduce depressive symptoms and the possibility of them coming back. […] Recovery-oriented psychosocial interventions include supported employment, supported housing, peer support, and social and life skills training. They serve to promote hope and to support the autonomy, personal empowerment and social inclusion of people with bipolar disorder. […] Medicines and psychological or psychosocial interventions should be tailored to the needs of the person and combined for best outcomes.

• #107 Bipolar Disorders: Evaluation and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2021/0215/p227.html

  Monotherapy with antidepressants is contraindicated in patients with mixed features, manic episodes, or bipolar I disorder. […] High-quality evidence supports the use of lithium, lamotrigine (Lamictal), quetiapine, quetiapine in combination with lithium or valproic acid, aripiprazole (Abilify), and olanzapine (Zyprexa) for maintenance therapy in patients who have bipolar disorders. […] Electroconvulsive therapy is effective for mania and psychotic depression. […] Behavioral interventions, including basic psychoeducation and cognitive behavior therapy, are evidence-based adjuncts to pharmacotherapy that improve social function and reduce the need for medications, number of hospitalizations, and relapse rates.

• #108 Bipolar Disorder | Mental Health America

  https://mhanational.org/conditions/bipolar-disorder/

  Bipolar disorder can be extremely distressing and disruptive for those who have this disease, their spouses, family members, friends, and employers. Although there is no known cure, bipolar disorder is treatable, and recovery is possible. Individuals with bipolar disorder can and do have successful relationships and meaningful jobs. The combination of medication, therapy, healthy lifestyle, and support helps the vast majority of people return to productive, fulfilling lives. […] A combination of medication, therapy, lifestyle changes, and support from family, friends and peers help individuals with bipolar disorder to stabilize their mood and to live the lives they want. Finding the treatment plan that works best for a person is critical for recovery. […] Medication: Common medications used in treating bipolar disorder are lithium, anticonvulsants, and mood stabilizers. Other medications used include antipsychotics, benzodiazepines, and beta-blockers. As with all medications, medications used to treat bipolar disorder can have mild to serious side effects so it is important to talk with your doctors about how you are feeling. Learn more about medications.

• #109 Bipolar Disorder Treatment: Creating the Right Plan for You

  https://www.helpguide.org/mental-health/bipolar-disorder/bipolar-disorder-treatment

  Learn how treatment for bipolar disorder, including medication, therapy, and lifestyle changes, can help you manage your symptoms, control mood swings, and improve your quality of life. […] Successful treatment of bipolar disorder depends on a combination of factors. Medication is just the start. In order to get the most out of treatment, its important to educate yourself about the illness, communicate with your doctors and therapists, have a strong support system, and help yourself by making healthy lifestyle choices that may reduce your need for medication. […] Recovering from bipolar disorder doesnt happen overnight. As with the mood swings of bipolar disorder, treatment has its own ups and downs. Finding the right treatments takes time and setbacks happen. But with careful management and a commitment to getting better, you can get your symptoms under control and live life to the fullest.

• #110 Bipolar Therapy Types: Behavioral, Cognitive, Interpersonal, and More

  https://www.webmd.com/bipolar-disorder/psychotherapy-bipolar-disorder

  Psychotherapy, or „talk” therapy, is an important part of treatment for bipolar disorder. During therapy, you can discuss feelings, thoughts, and behaviors that cause you problems. Talk therapy can help you understand and hopefully master any problems that hurt your ability to function well in your life and career. It also helps you stay on your medication. It can help you maintain a positive self-image. […] The types of psychotherapy used to treat bipolar disorder include: […] Support groups also help people with bipolar disorder. You receive encouragement, learn coping skills, and share concerns. You may feel less isolated as a result. Family members and friends may also benefit from a support group. They can gain a better understanding of the illness, share their concerns, and learn how to best support loved ones with bipolar disorder.

• #111 5 Types of Therapy for Bipolar Disorder — Talkspace

  https://www.talkspace.com/mental-health/conditions/bipolar-disorder/therapy-treatment-types/

  Many people with bipolar disorder find it helpful to get together with a group of other people who live with the condition. […] According to researchers, group therapy can be extremely successful and beneficial in preventing relapse. […] It’s crucial that you explore ways you can complement medication protocols and a mood stabilizer prescription with the use of ongoing online therapy and bipolar disorder natural treatment.

• #112 Bipolar Therapy Types: Behavioral, Cognitive, Interpersonal, and More

  https://www.webmd.com/bipolar-disorder/psychotherapy-bipolar-disorder

  Education is another integral part of treatment for you and your family. People with bipolar disorder (and their families) often benefit from learning about the disorder — its symptoms, early signs of an episode, and types of treatment. This type of education can also help to come up with a plan in case your insight or ability to see your system is compromised. […] Establish routines. Regular sleep, eating, and activity appear to help people with bipolar disorder manage their moods. […] Identify symptoms. Even though the early warning signs of an approaching episode vary from person to person, together with a psychiatrist you can identify what behavior changes signal the onset of an episode for you. […] Adapt. This can help you avoid embarrassing behavior during manic episodes and set realistic goals for treatment.

• #113 Treatment – International Bipolar Foundation

  https://ibpf.org/learn/education/treatment/

  Find the treatment that works for you. […] Medication is the cornerstone on bipolar disorder treatment. Taking a mood stabilizing medication can help minimize the highs and lows of bipolar disorder and keep symptoms under control. […] Therapy is essential for dealing with bipolar disorder and the problems it has caused in your life. […] Education is a key component of treatment. The more you and your loved ones know about bipolar disorder, the better able you will be to avoid problems and deal with setbacks. […] Living with bipolar disorder can be challenging, and having a solid support system in place can make all the difference in your outlook and motivation. […] Most people with bipolar disorder need medication in order to keep their symptoms under control. […] Continue taking your medication, even if your mood is stable.

• #114 Bipolar disorder – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/bipolar-disorder/diagnosis-treatment/drc-20355961

  Depending on your needs, your health professional may add other treatments to your depression therapy, such as: Electroconvulsive therapy, also known as ECT. During ECT, electrical currents pass through the brain, causing a brief seizure. ECT seems to change brain chemistry, which can reverse symptoms of certain mental illnesses. ECT may be an option to treat bipolar disorder if you don’t get better with medicines, can’t take antidepressants for health reasons such as pregnancy or are at high risk of attempting suicide. […] Talk therapy. Initial and long-term therapy can help keep symptoms from returning. Talk therapy, also known as psychotherapy, can help children and teens manage their routines, cope better, handle learning difficulties, make social problems better, and make family bonds and communication stronger. […] Psychoeducation can include learning the symptoms of bipolar disorder and how they differ from behavior related to your child’s age, the situation and appropriate cultural behavior. Knowing more about bipolar disorder also can help you support your child.

• #115 Bipolar Disorder | Mental Health America

  https://mhanational.org/conditions/bipolar-disorder/

  Therapy: Both group and individual therapy can be helpful in bipolar disorder. Common types of therapy used are Cognitive Behavioral Therapy (CBT), Dialectical Behavior Therapy (DBT), and family-focused therapies. Learn more about therapy. […] Lifestyle changes: Healthy lifestyles changes can be an important part of overall recovery. This includes: sticking to a regular sleep schedule; reducing consumption of alcohol, caffeine, and similar substances; and exercising regularly. Some may use meditation, mind-body practices, and spirituality as resources as well. Learn more about living a healthy lifestyle. […] Support: Support and self-help groups are invaluable resources for learning coping skills, feeling accepted, and avoiding social isolation. In addition to in-person support groups and drop-in centers, there are many online communities where individuals can also find support. Additional support can be provided through employment, housing, and psychosocial rehabilitation programs. Learn more about recovery and support.

• #116 Bipolar Therapy Types: Behavioral, Cognitive, Interpersonal, and More

  https://www.webmd.com/bipolar-disorder/psychotherapy-bipolar-disorder

  Education is another integral part of treatment for you and your family. People with bipolar disorder (and their families) often benefit from learning about the disorder — its symptoms, early signs of an episode, and types of treatment. This type of education can also help to come up with a plan in case your insight or ability to see your system is compromised. […] Establish routines. Regular sleep, eating, and activity appear to help people with bipolar disorder manage their moods. […] Identify symptoms. Even though the early warning signs of an approaching episode vary from person to person, together with a psychiatrist you can identify what behavior changes signal the onset of an episode for you. […] Adapt. This can help you avoid embarrassing behavior during manic episodes and set realistic goals for treatment.

• #117 Bipolar Therapy Types: Behavioral, Cognitive, Interpersonal, and More

  https://www.webmd.com/bipolar-disorder/psychotherapy-bipolar-disorder

  Maintain a regular sleep pattern. Go to bed and wake up around the same time each day. Changes in sleep can disrupt the normal functioning of brain circuits involved in the processing of emotions, potentially triggering mood episodes. […] Do not use alcohol or street drugs. These substances can trigger or mimic mood episodes. They can also interfere with the effectiveness of medication.

• #118 Bipolar disorder – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/bipolar-disorder/diagnosis-treatment/drc-20355961

  Treatment is best guided by a medical doctor who diagnoses and treats mental health conditions (psychiatrist) who is skilled in treating bipolar and related disorders. Your care team also may include a psychologist, social worker or psychiatric nurse. […] Bipolar disorder is a lifelong condition, with treatment directed to manage symptoms. […] The main treatments for bipolar disorder include medicines and talk therapy, also known as psychotherapy, to control symptoms. Treatment also may include education and support groups. […] Talk therapy, also called psychotherapy, is a vital part of bipolar disorder treatment. This treatment can be provided in individual, family or group settings. […] Several types of therapy may help, including: Interpersonal and social rhythm therapy. This therapy focuses on stabilizing daily rhythms, including sleeping, waking and eating. A consistent routine helps manage moods. A daily routine for sleep, diet and exercise may help people with bipolar disorder.

• #119 Management of Bipolar Disorder | AAFP

  https://www.aafp.org/pubs/afp/issues/2000/0915/p1343.html

  Bipolar disorder most commonly is diagnosed in persons between 18 and 24 years of age. […] Effective mood stabilizers include lithium, valproic acid and carbamazepine. A comprehensive management program, including collaboration between the patient’s family physician and psychiatrist, should be implemented to optimize medical care. […] If a patient with symptoms of acute mania presents to the office, a psychiatrist should be consulted, and the patient should be evaluated urgently. […] Patients with newly diagnosed bipolar disorder require a medical evaluation along with a psychiatric evaluation. […] Given the chronic nature of bipolar disorder and its impact on the entire family, it is important for the patient’s family physician and psychiatrist to develop an effective and collaborative relationship.

• #120 Available Bipolar Disorder Treatments to Consider

  https://www.verywellhealth.com/bipolar-disorder-treatments-8425817

  Lifestyle and complementary treatments for bipolar disorder include: Getting regular exercise, Practicing sleep hygiene, Eating a nutrient-dense and balanced diet, Planning enjoyable activities that give feelings of achievement, Engaging in light therapy, Taking n-acetylcysteine supplements, Abstaining from alcohol and other substances, which can make bipolar disorder worse. […] An important stage in bipolar treatment is choosing the setting. Depending on the severity of symptoms, a healthcare provider may recommend a residential or inpatient facility for those having severe symptoms and requiring extra support to ensure their safety and recovery. […] Treatment for bipolar disorder is typically guided by a psychiatrist in combination with other health professionals, such as counselors, therapists, and social workers. […] People with bipolar disorder require lifelong treatment, which typically includes a combination of prescription medications, psychotherapy, and lifestyle changes.

• #121 Bipolar Disorder Treatment & Management: Approach Considerations, Indications for Inpatient Management, Considerations for Partial Hospitalization or Day Treatment

  https://emedicine.medscape.com/article/286342-treatment

  Evaluate and closely monitor patients with bipolar depression for the risk for mood destabilization or switching to mania and for the presence of emergent symptoms following initiation of pharmacotherapy for a depressive episode. […] Initiate an antipsychotic agent in patients with bipolar depression with psychotic features, and consider psychosocial interventions (eg, psychoeducation; psychotherapy strategies such as cognitive behavioral therapy [CBT], interpersonal and social rhythm therapy [IPSRT], family focused therapy; chronic care model-based interventions). […] The patients response to treatment may depend on the number of previous episodes of bipolar disorder. […] If the patient is in a short-term inpatient care unit and has not made significant progress, reevaluate the management strategy.

• #122 Bipolar Disorder Treatment & Management: Approach Considerations, Indications for Inpatient Management, Considerations for Partial Hospitalization or Day Treatment

  https://emedicine.medscape.com/article/286342-treatment

  All patients with bipolar disorder need outpatient monitoring for both medications and psychotherapy. […] The 2010 Veterans Administration/Department of Defense (VA/DoD) clinical practice guideline for management of bipolar disorder recommends reassessing patients who start treatment for acute bipolar mania, hypomania, or mixed episodes every 12 weeks for at least 6 weeks. […] Evaluate the patients response to treatment with the same standardized tool at follow-up visits, after changes in therapy, and with periodic assessments until complete remission has been reached. […] No surgical care is indicated for bipolar disorder. […] Patients diagnosed with bipolar mania or depression and severe symptoms must be referred for urgent/emergent mental health intervention. […] The indications for inpatient treatment in a person with bipolar disorder include the following: Danger to self, Danger to others, Delirium, Marked psychotic symptoms, Total inability to function, Total loss of control (eg, excessive spending, undertaking a dangerous trip), Medical conditions that warrant medication monitoring (eg, substance withdrawal/intoxication).

• #123 Bipolar Disorder Treatment & Management: Approach Considerations, Indications for Inpatient Management, Considerations for Partial Hospitalization or Day Treatment

  https://emedicine.medscape.com/article/286342-treatment

  All patients with bipolar disorder need outpatient monitoring for both medications and psychotherapy. […] The 2010 Veterans Administration/Department of Defense (VA/DoD) clinical practice guideline for management of bipolar disorder recommends reassessing patients who start treatment for acute bipolar mania, hypomania, or mixed episodes every 12 weeks for at least 6 weeks. […] Evaluate the patients response to treatment with the same standardized tool at follow-up visits, after changes in therapy, and with periodic assessments until complete remission has been reached. […] No surgical care is indicated for bipolar disorder. […] Patients diagnosed with bipolar mania or depression and severe symptoms must be referred for urgent/emergent mental health intervention. […] The indications for inpatient treatment in a person with bipolar disorder include the following: Danger to self, Danger to others, Delirium, Marked psychotic symptoms, Total inability to function, Total loss of control (eg, excessive spending, undertaking a dangerous trip), Medical conditions that warrant medication monitoring (eg, substance withdrawal/intoxication).

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