Materiały źródłowe

• #1 Hyperthyroidism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK537053/

  The 1977 Whickham Survey evaluated the spectrum of thyroid disorders in County Durham in northeastern England. The Whickham Survey demonstrated a prevalence of hyperthyroidism in women, approximately 10 times more than that of men (2.7% versus 0.23%). The prevalence of hyperthyroidism in the United States was 1.3% in the general population, with 0.5% cases of overt hyperthyroidism and 0.7% cases of subclinical hyperthyroidism. A meta-analysis found the prevalence of hyperthyroidism in Europe to be 0.75%. The prevalence of overt hyperthyroidism is similar in China at 0.78%. Amiodarone-induced thyrotoxicosis (AIT) is seen in about 6% of the individuals taking the medication in iodine-sufficient areas and about 10% in individuals taking the medication from iodine-deficient areas.

• #2 Hyperthyroidism

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5014602/

  Prevalence of hyperthyroidism is 08% in Europe, and 13% in the USA. Hyperthyroidism increases with age and is more frequent in women. The prevalence of overt hyperthyroidism is 0508% in Europe, and 05% in the USA. […] Data for ethnic differences are scarce, but hyperthyroidism seems to be slightly more frequent in white people than in other races. The incidence of mild hyperthyroidism is also reported to be higher in iodine-deficient areas than in iodine-sufficient areas, and to decrease after introduction of universal salt iodisation programmes.

• #3 Disorders that cause hyperthyroidism – UpToDate

  https://www.uptodate.com/contents/disorders-that-cause-hyperthyroidism

  Several different disorders can cause hyperthyroidism. It is essential that the correct cause be identified because appropriate therapy depends upon the underlying mechanism of the hyperthyroidism. […] The global prevalence of hyperthyroidism is 0.2 to 1.4 percent. In the United States, the overall prevalence of hyperthyroidism is approximately 1.3 percent, and it increases to 4 to 5 percent in older women. Hyperthyroidism is more common in women than men (5:1 ratio), and in smokers. Graves’ disease is seen most often in younger women and in regions of iodine sufficiency, while toxic nodular goiter is more common in older women and in regions of mild to moderate iodine deficiency.

• #4 Hyperthyroidism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK537053/

  The 1977 Whickham Survey evaluated the spectrum of thyroid disorders in County Durham in northeastern England. The Whickham Survey demonstrated a prevalence of hyperthyroidism in women, approximately 10 times more than that of men (2.7% versus 0.23%). The prevalence of hyperthyroidism in the United States was 1.3% in the general population, with 0.5% cases of overt hyperthyroidism and 0.7% cases of subclinical hyperthyroidism. A meta-analysis found the prevalence of hyperthyroidism in Europe to be 0.75%. The prevalence of overt hyperthyroidism is similar in China at 0.78%. Amiodarone-induced thyrotoxicosis (AIT) is seen in about 6% of the individuals taking the medication in iodine-sufficient areas and about 10% in individuals taking the medication from iodine-deficient areas.

• #5 Hyperthyroidism: Diagnosis and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2016/0301/p363.html

  In the United States, the overall prevalence of hyperthyroidism is 1.2%, and the prevalences of overt hyperthyroidism and subclinical hyperthyroidism are 0.5% and 0.7%, respectively.1 […] Toxic multinodular goiter is the second most common cause of hyperthyroidism in the United States and the most common cause in older persons living in iodine-deficient areas.2 […] In a Danish study, its prevalence among patients with thyrotoxicosis was 0.5%, as evaluated by scintigraphy.6 […] The clinical presentation of hyperthyroidism ranges from asymptomatic to thyroid storm. […] Clinical suspicion of hyperthyroidism should prompt laboratory testing. […] A radioactive iodine uptake test and thyroid scan help determine the cause of hyperthyroidism. […] Radioactive iodine ablation of the thyroid gland is the most common treatment of Graves disease in the United States. It is contraindicated in pregnancy.

• #6 Hyperthyroidism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK537053/

  The 1977 Whickham Survey evaluated the spectrum of thyroid disorders in County Durham in northeastern England. The Whickham Survey demonstrated a prevalence of hyperthyroidism in women, approximately 10 times more than that of men (2.7% versus 0.23%). The prevalence of hyperthyroidism in the United States was 1.3% in the general population, with 0.5% cases of overt hyperthyroidism and 0.7% cases of subclinical hyperthyroidism. A meta-analysis found the prevalence of hyperthyroidism in Europe to be 0.75%. The prevalence of overt hyperthyroidism is similar in China at 0.78%. Amiodarone-induced thyrotoxicosis (AIT) is seen in about 6% of the individuals taking the medication in iodine-sufficient areas and about 10% in individuals taking the medication from iodine-deficient areas.

• #7 Hyperthyroidism

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5014602/

  Prevalence of hyperthyroidism is 08% in Europe, and 13% in the USA. Hyperthyroidism increases with age and is more frequent in women. The prevalence of overt hyperthyroidism is 0508% in Europe, and 05% in the USA. […] Data for ethnic differences are scarce, but hyperthyroidism seems to be slightly more frequent in white people than in other races. The incidence of mild hyperthyroidism is also reported to be higher in iodine-deficient areas than in iodine-sufficient areas, and to decrease after introduction of universal salt iodisation programmes.

• #8 Hyperthyroidism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK537053/

  The 1977 Whickham Survey evaluated the spectrum of thyroid disorders in County Durham in northeastern England. The Whickham Survey demonstrated a prevalence of hyperthyroidism in women, approximately 10 times more than that of men (2.7% versus 0.23%). The prevalence of hyperthyroidism in the United States was 1.3% in the general population, with 0.5% cases of overt hyperthyroidism and 0.7% cases of subclinical hyperthyroidism. A meta-analysis found the prevalence of hyperthyroidism in Europe to be 0.75%. The prevalence of overt hyperthyroidism is similar in China at 0.78%. Amiodarone-induced thyrotoxicosis (AIT) is seen in about 6% of the individuals taking the medication in iodine-sufficient areas and about 10% in individuals taking the medication from iodine-deficient areas.

• #9 Graves’ disease | healthdirect

  https://www.healthdirect.gov.au/graves-disease

  Graves’ disease is the most common cause of hyperthyroidism (an overactive thyroid gland). […] Hyperthyroidism is a health condition where your thyroid becomes overactive and produces too many hormones. It is a serious health condition that is fatal if left undiagnosed or untreated. […] In Australia, it is estimated that hyperthyroidism affects 3 in 1000 people. […] The Endocrine Society of Australia has information about the symptoms, diagnosis and treatment of hyperthyroidism.

• #10 Hyperthyroidism – Hormones Australia

  https://www.hormones-australia.org.au/endocrine-diseases/hyperthyroidism/

  Hyperthyroidism is a condition where the thyroid gland becomes overactive and produces too much thyroid hormone. […] In Australia, it is estimated that hyperthyroidism affects 3 in 1000 people. […] Your doctor may ask you questions about your personal health and your family’s health history. This will include questions about any thyroid disease, autoimmune disorders, current and previous medications, other medical conditions or concerns and, for women, your pregnancy history. […] If symptoms suggest hyperthyroidism, your doctor will order a blood test to measure the level of thyroid hormones (T4 T3) and thyroid stimulating hormone (TSH). […] The presence of TSH-receptor antibodies and/or TPO antibodies means the hyperthyroidism is caused by Graves disease. […] If the scan shows a marked increase in uptake of the radioactive tracer (i.e. is a hot scan) Graves disease is confirmed.

• #11 Epidemiology of Hypothyroidism, Hyperthyroidism and Positive Thyroid Antibodies in the Croatian Population

  https://www.mdpi.com/2079-7737/11/3/394

  The aim of this paper was to analyse the prevalence of hypothyroidism and hyperthyroidism in the Croatian population. This is the first epidemiological study of its kind conducted in our population. […] The results of our study conducted on 4402 individuals, showed a higher prevalence of hypothyroidism in our country (10.5%) compared to other countries, while the prevalence of hyperthyroidism was quite similar (1.3%). […] We also observed that a high proportion of thyroid disorders remained undiagnosed (as many as 92.6% subclinical hypothyroid, 93.9% clinical hypothyroid, 83% subclinical hyperthyroid and 71.4% clinical hyperthyroid participants). […] The results of our study showed that the prevalence of clinical and subclinical hypothyroidism was 3% and 7.4%, respectively, while the prevalence of clinical and subclinical hyperthyroidism was 0.2% and 1.1%, respectively.

• #12 Disorders that cause hyperthyroidism – UpToDate

  https://www.uptodate.com/contents/disorders-that-cause-hyperthyroidism

  Several different disorders can cause hyperthyroidism. It is essential that the correct cause be identified because appropriate therapy depends upon the underlying mechanism of the hyperthyroidism. […] The global prevalence of hyperthyroidism is 0.2 to 1.4 percent. In the United States, the overall prevalence of hyperthyroidism is approximately 1.3 percent, and it increases to 4 to 5 percent in older women. Hyperthyroidism is more common in women than men (5:1 ratio), and in smokers. Graves’ disease is seen most often in younger women and in regions of iodine sufficiency, while toxic nodular goiter is more common in older women and in regions of mild to moderate iodine deficiency.

• #13 Hyperthyroidism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK537053/

  The 1977 Whickham Survey evaluated the spectrum of thyroid disorders in County Durham in northeastern England. The Whickham Survey demonstrated a prevalence of hyperthyroidism in women, approximately 10 times more than that of men (2.7% versus 0.23%). The prevalence of hyperthyroidism in the United States was 1.3% in the general population, with 0.5% cases of overt hyperthyroidism and 0.7% cases of subclinical hyperthyroidism. A meta-analysis found the prevalence of hyperthyroidism in Europe to be 0.75%. The prevalence of overt hyperthyroidism is similar in China at 0.78%. Amiodarone-induced thyrotoxicosis (AIT) is seen in about 6% of the individuals taking the medication in iodine-sufficient areas and about 10% in individuals taking the medication from iodine-deficient areas.

• #14 Graves’ Disease

  https://www.thyroid.org/graves-disease/

  Graves disease is an autoimmune disease that leads to a generalized overactivity of the entire thyroid gland (hyperthyroidism). It is the most common cause of hyperthyroidism in the United States. It is 7-8 times more common in women than men. […] The diagnosis of hyperthyroidism is made on the basis of your symptoms and findings during a physical exam and it is confirmed by laboratory tests that measure the amount of thyroid hormones (thyroxine, or T4, and triiodothyronine, or T3) and thyroid-stimulating hormone (TSH) in your blood. […] The treatment of hyperthyroidism is described in detail in the Hyperthyroidism brochure. Hyperthyroidism due to Graves disease is, in general, controllable and safely treated and treatment is almost always successful.

• #15 Hyperthyroidism (overactive thyroid) | Doctor

  https://patient.info/doctor/hyperthyroidism

  Hyperthyroidism is overactivity of the thyroid gland, which results in a number of symptoms and signs. It can be primary or secondary: […] In Europe, thyrotoxicosis affects around 1 in 2,000 people annually. There is a global prevalence of 0.2 – 2.5%. Thyrotoxicosis is still under-diagnosed however – it has been shown that in people older than 65 years, undiagnosed hyperthyroidism occurs in 0.3% of people and around 2% of people aged over 65 years have subclinical hyperthyroidism. Graves’ disease in adults affects approximately 2% of women and 0.2% of men. Graves’ disease accounts for around 75% of cases. […] Subclinical hyperthyroidism occurs in around 2% of the elderly population. The most common cause of true subclinical hyperthyroidism is toxic nodular goitre, especially in the elderly. Subclinical hyperthyroidism is associated with increased risks of coronary heart disease (CHD) mortality and incident atrial fibrillation, with highest risks of CHD mortality and atrial fibrillation when thyrotropin level is lower than 0.10 mIU/L. Subclinical hyperthyroidism is also associated with an increased risk of hip and other fractures, particularly among those with TSH levels of less than 0.10 mIU/L.

• #16 Hyperthyroidism and Thyrotoxicosis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/767130-overview

  Graves disease is the most common form of hyperthyroidism in the United States, causing approximately 60-80% of cases of thyrotoxicosis. The annual incidence of Graves disease was found to be 0.5 cases per 1000 population during a 20-year period, with the peak occurrence in people aged 20-40 years. […] Toxic multinodular goiter (15-20% of thyrotoxicosis) occurs more frequently in regions of iodine deficiency. Most persons in the United States receive sufficient iodine, and the incidence of toxic multinodular goiter in the US population is lower than that in areas of the world with iodine deficiency. Toxic adenoma is the cause of 3-5% of cases of thyrotoxicosis. […] The incidences of Graves disease and toxic multinodular goiter change with iodine intake. Compared with regions of the world with less iodine intake, the United States has more cases of Graves disease and fewer cases of toxic multinodular goiters.

• #17 Hyperthyroidism and Thyrotoxicosis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/767130-overview

  Graves disease is the most common form of hyperthyroidism in the United States, causing approximately 60-80% of cases of thyrotoxicosis. The annual incidence of Graves disease was found to be 0.5 cases per 1000 population during a 20-year period, with the peak occurrence in people aged 20-40 years. […] Toxic multinodular goiter (15-20% of thyrotoxicosis) occurs more frequently in regions of iodine deficiency. Most persons in the United States receive sufficient iodine, and the incidence of toxic multinodular goiter in the US population is lower than that in areas of the world with iodine deficiency. Toxic adenoma is the cause of 3-5% of cases of thyrotoxicosis. […] The incidences of Graves disease and toxic multinodular goiter change with iodine intake. Compared with regions of the world with less iodine intake, the United States has more cases of Graves disease and fewer cases of toxic multinodular goiters.

• #18 Hyperthyroidism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK537053/

  Hyperthyroidism is a common thyroid disorder with multiple underlying etiologies. This disease is characterized by excess thyroid hormone production. Hyperthyroidism is associated with significant short-term and long-term morbidity. Therefore, early recognition of this condition and timely instruction of appropriate therapy is critical. […] The prevalence of hyperthyroidism varies worldwide, based on dietary iodine content. Hyperthyroidism is more common in women compared to men. Other risk factors associated with the development of hyperthyroidism include smoking, iodine deficiency, iodine excess, selenium deficiency, genetic factors, and the use of certain drugs. Graves disease is typically seen in younger patients and is the most common cause of hyperthyroidism in this demographic. The incidence of Graves disease is highest between the age group of 30 to 50 years.

• #19 Hyperthyroidism: Diagnosis and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2016/0301/p363.html

  In the United States, the overall prevalence of hyperthyroidism is 1.2%, and the prevalences of overt hyperthyroidism and subclinical hyperthyroidism are 0.5% and 0.7%, respectively.1 […] Toxic multinodular goiter is the second most common cause of hyperthyroidism in the United States and the most common cause in older persons living in iodine-deficient areas.2 […] In a Danish study, its prevalence among patients with thyrotoxicosis was 0.5%, as evaluated by scintigraphy.6 […] The clinical presentation of hyperthyroidism ranges from asymptomatic to thyroid storm. […] Clinical suspicion of hyperthyroidism should prompt laboratory testing. […] A radioactive iodine uptake test and thyroid scan help determine the cause of hyperthyroidism. […] Radioactive iodine ablation of the thyroid gland is the most common treatment of Graves disease in the United States. It is contraindicated in pregnancy.

• #20 Disorders that cause hyperthyroidism – UpToDate

  https://www.uptodate.com/contents/disorders-that-cause-hyperthyroidism

  Several different disorders can cause hyperthyroidism. It is essential that the correct cause be identified because appropriate therapy depends upon the underlying mechanism of the hyperthyroidism. […] The global prevalence of hyperthyroidism is 0.2 to 1.4 percent. In the United States, the overall prevalence of hyperthyroidism is approximately 1.3 percent, and it increases to 4 to 5 percent in older women. Hyperthyroidism is more common in women than men (5:1 ratio), and in smokers. Graves’ disease is seen most often in younger women and in regions of iodine sufficiency, while toxic nodular goiter is more common in older women and in regions of mild to moderate iodine deficiency.

• #21 Hyperthyroidism (overactive thyroid) | Doctor

  https://patient.info/doctor/hyperthyroidism

  Hyperthyroidism is overactivity of the thyroid gland, which results in a number of symptoms and signs. It can be primary or secondary: […] In Europe, thyrotoxicosis affects around 1 in 2,000 people annually. There is a global prevalence of 0.2 – 2.5%. Thyrotoxicosis is still under-diagnosed however – it has been shown that in people older than 65 years, undiagnosed hyperthyroidism occurs in 0.3% of people and around 2% of people aged over 65 years have subclinical hyperthyroidism. Graves’ disease in adults affects approximately 2% of women and 0.2% of men. Graves’ disease accounts for around 75% of cases. […] Subclinical hyperthyroidism occurs in around 2% of the elderly population. The most common cause of true subclinical hyperthyroidism is toxic nodular goitre, especially in the elderly. Subclinical hyperthyroidism is associated with increased risks of coronary heart disease (CHD) mortality and incident atrial fibrillation, with highest risks of CHD mortality and atrial fibrillation when thyrotropin level is lower than 0.10 mIU/L. Subclinical hyperthyroidism is also associated with an increased risk of hip and other fractures, particularly among those with TSH levels of less than 0.10 mIU/L.

• #22 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  Annual Incidence: New cases of hyperthyroidism occur at an annual rate of roughly 20–50 per 100,000 people in iodine-sufficient populations. Graves’ disease (autoimmune hyperthyroidism) has an incidence around 0.5 cases per 1,000 per year (i.e. 50 per 100,000) in the general population, with peaks in younger adults. A large study in Italy found an overall hyperthyroidism incidence of 54 per 100,000 person-years. In Europe, the average incidence is reported around 51 per 100,000 per year. These rates indicate that for every 100,000 people, roughly 50 will be diagnosed with hyperthyroidism each year. Subclinical hyperthyroidism is more frequently detected: it affects an additional 1–2% of people per year in some cohorts, though many cases may be transient or mild. […] Historical Trends: The incidence and hospitalization rates for hyperthyroidism have shown some declines in recent decades, likely due to better iodine nutrition and improved outpatient management. For example, in the iodine-deficient Veneto region of Italy, the introduction of salt iodization since 2005 led to a significant drop in new hyperthyroidism cases, especially those due to nodular goiter. Similarly, in the U.S., hospitalizations for hyperthyroidism fell by 28% from 2008 to 2018 (from 12,689 to 9,110 annual hospital stays). This likely reflects earlier diagnosis and treatment on an outpatient basis, preventing severe cases that require admission.

• #23 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  Annual Incidence: New cases of hyperthyroidism occur at an annual rate of roughly 20–50 per 100,000 people in iodine-sufficient populations. Graves’ disease (autoimmune hyperthyroidism) has an incidence around 0.5 cases per 1,000 per year (i.e. 50 per 100,000) in the general population, with peaks in younger adults. A large study in Italy found an overall hyperthyroidism incidence of 54 per 100,000 person-years. In Europe, the average incidence is reported around 51 per 100,000 per year. These rates indicate that for every 100,000 people, roughly 50 will be diagnosed with hyperthyroidism each year. Subclinical hyperthyroidism is more frequently detected: it affects an additional 1–2% of people per year in some cohorts, though many cases may be transient or mild. […] Historical Trends: The incidence and hospitalization rates for hyperthyroidism have shown some declines in recent decades, likely due to better iodine nutrition and improved outpatient management. For example, in the iodine-deficient Veneto region of Italy, the introduction of salt iodization since 2005 led to a significant drop in new hyperthyroidism cases, especially those due to nodular goiter. Similarly, in the U.S., hospitalizations for hyperthyroidism fell by 28% from 2008 to 2018 (from 12,689 to 9,110 annual hospital stays). This likely reflects earlier diagnosis and treatment on an outpatient basis, preventing severe cases that require admission.

• #24 Hyperthyroidism and Thyrotoxicosis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/767130-overview

  Graves disease is the most common form of hyperthyroidism in the United States, causing approximately 60-80% of cases of thyrotoxicosis. The annual incidence of Graves disease was found to be 0.5 cases per 1000 population during a 20-year period, with the peak occurrence in people aged 20-40 years. […] Toxic multinodular goiter (15-20% of thyrotoxicosis) occurs more frequently in regions of iodine deficiency. Most persons in the United States receive sufficient iodine, and the incidence of toxic multinodular goiter in the US population is lower than that in areas of the world with iodine deficiency. Toxic adenoma is the cause of 3-5% of cases of thyrotoxicosis. […] The incidences of Graves disease and toxic multinodular goiter change with iodine intake. Compared with regions of the world with less iodine intake, the United States has more cases of Graves disease and fewer cases of toxic multinodular goiters.

• #25 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  Annual Incidence: New cases of hyperthyroidism occur at an annual rate of roughly 20–50 per 100,000 people in iodine-sufficient populations. Graves’ disease (autoimmune hyperthyroidism) has an incidence around 0.5 cases per 1,000 per year (i.e. 50 per 100,000) in the general population, with peaks in younger adults. A large study in Italy found an overall hyperthyroidism incidence of 54 per 100,000 person-years. In Europe, the average incidence is reported around 51 per 100,000 per year. These rates indicate that for every 100,000 people, roughly 50 will be diagnosed with hyperthyroidism each year. Subclinical hyperthyroidism is more frequently detected: it affects an additional 1–2% of people per year in some cohorts, though many cases may be transient or mild. […] Historical Trends: The incidence and hospitalization rates for hyperthyroidism have shown some declines in recent decades, likely due to better iodine nutrition and improved outpatient management. For example, in the iodine-deficient Veneto region of Italy, the introduction of salt iodization since 2005 led to a significant drop in new hyperthyroidism cases, especially those due to nodular goiter. Similarly, in the U.S., hospitalizations for hyperthyroidism fell by 28% from 2008 to 2018 (from 12,689 to 9,110 annual hospital stays). This likely reflects earlier diagnosis and treatment on an outpatient basis, preventing severe cases that require admission.

• #26 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  Annual Incidence: New cases of hyperthyroidism occur at an annual rate of roughly 20–50 per 100,000 people in iodine-sufficient populations. Graves’ disease (autoimmune hyperthyroidism) has an incidence around 0.5 cases per 1,000 per year (i.e. 50 per 100,000) in the general population, with peaks in younger adults. A large study in Italy found an overall hyperthyroidism incidence of 54 per 100,000 person-years. In Europe, the average incidence is reported around 51 per 100,000 per year. These rates indicate that for every 100,000 people, roughly 50 will be diagnosed with hyperthyroidism each year. Subclinical hyperthyroidism is more frequently detected: it affects an additional 1–2% of people per year in some cohorts, though many cases may be transient or mild. […] Historical Trends: The incidence and hospitalization rates for hyperthyroidism have shown some declines in recent decades, likely due to better iodine nutrition and improved outpatient management. For example, in the iodine-deficient Veneto region of Italy, the introduction of salt iodization since 2005 led to a significant drop in new hyperthyroidism cases, especially those due to nodular goiter. Similarly, in the U.S., hospitalizations for hyperthyroidism fell by 28% from 2008 to 2018 (from 12,689 to 9,110 annual hospital stays). This likely reflects earlier diagnosis and treatment on an outpatient basis, preventing severe cases that require admission.

• #27 Hyperthyroidism: Diagnosis and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2016/0301/p363.html

  In the United States, the overall prevalence of hyperthyroidism is 1.2%, and the prevalences of overt hyperthyroidism and subclinical hyperthyroidism are 0.5% and 0.7%, respectively.1 […] Toxic multinodular goiter is the second most common cause of hyperthyroidism in the United States and the most common cause in older persons living in iodine-deficient areas.2 […] In a Danish study, its prevalence among patients with thyrotoxicosis was 0.5%, as evaluated by scintigraphy.6 […] The clinical presentation of hyperthyroidism ranges from asymptomatic to thyroid storm. […] Clinical suspicion of hyperthyroidism should prompt laboratory testing. […] A radioactive iodine uptake test and thyroid scan help determine the cause of hyperthyroidism. […] Radioactive iodine ablation of the thyroid gland is the most common treatment of Graves disease in the United States. It is contraindicated in pregnancy.

• #28 Epidemiology of Hypothyroidism, Hyperthyroidism and Positive Thyroid Antibodies in the Croatian Population

  https://www.mdpi.com/2079-7737/11/3/394

  The aim of this paper was to analyse the prevalence of hypothyroidism and hyperthyroidism in the Croatian population. This is the first epidemiological study of its kind conducted in our population. […] The results of our study conducted on 4402 individuals, showed a higher prevalence of hypothyroidism in our country (10.5%) compared to other countries, while the prevalence of hyperthyroidism was quite similar (1.3%). […] We also observed that a high proportion of thyroid disorders remained undiagnosed (as many as 92.6% subclinical hypothyroid, 93.9% clinical hypothyroid, 83% subclinical hyperthyroid and 71.4% clinical hyperthyroid participants). […] The results of our study showed that the prevalence of clinical and subclinical hypothyroidism was 3% and 7.4%, respectively, while the prevalence of clinical and subclinical hyperthyroidism was 0.2% and 1.1%, respectively.

• #29 Epidemiology of Hypothyroidism, Hyperthyroidism and Positive Thyroid Antibodies in the Croatian Population

  https://www.mdpi.com/2079-7737/11/3/394

  The aim of this paper was to analyse the prevalence of hypothyroidism and hyperthyroidism in the Croatian population. This is the first epidemiological study of its kind conducted in our population. […] The results of our study conducted on 4402 individuals, showed a higher prevalence of hypothyroidism in our country (10.5%) compared to other countries, while the prevalence of hyperthyroidism was quite similar (1.3%). […] We also observed that a high proportion of thyroid disorders remained undiagnosed (as many as 92.6% subclinical hypothyroid, 93.9% clinical hypothyroid, 83% subclinical hyperthyroid and 71.4% clinical hyperthyroid participants). […] The results of our study showed that the prevalence of clinical and subclinical hypothyroidism was 3% and 7.4%, respectively, while the prevalence of clinical and subclinical hyperthyroidism was 0.2% and 1.1%, respectively.

• #30 Epidemiology of Hypothyroidism, Hyperthyroidism and Positive Thyroid Antibodies in the Croatian Population

  https://www.mdpi.com/2079-7737/11/3/394

  Additionally, 17.6% of participants were euthyroid with positive antibodies. Most of these cases had not been previously diagnosed. […] The prevalence of undiagnosed subclinical and clinical hypothyroidism in our population was 6.9% and 2.8%, respectively, while the prevalence of undiagnosed subclinical and clinical hyperthyroidism was 0.9% and 0.1%, respectively. […] Thus, in our population, as much as 92.6% of subclinical hypothyroid, 93.9% of clinical hypothyroid, 83% of subclinical hyperthyroid, and 71.4% of clinical hyperthyroid participants were undiagnosed. […] Our current study showed that a high proportion of thyroid dysfunction remained undiagnosed (as much as 92.6% subclinical hypothyroid, 93.9% clinical hypothyroid, 83% subclinical hyperthyroid, and 71.4% clinical hyperthyroid participants). Another important finding is the high prevalence of hypothyroidism among Croatians.

• #31 Epidemiology of Hypothyroidism, Hyperthyroidism and Positive Thyroid Antibodies in the Croatian Population

  https://www.mdpi.com/2079-7737/11/3/394

  Additionally, 17.6% of participants were euthyroid with positive antibodies. Most of these cases had not been previously diagnosed. […] The prevalence of undiagnosed subclinical and clinical hypothyroidism in our population was 6.9% and 2.8%, respectively, while the prevalence of undiagnosed subclinical and clinical hyperthyroidism was 0.9% and 0.1%, respectively. […] Thus, in our population, as much as 92.6% of subclinical hypothyroid, 93.9% of clinical hypothyroid, 83% of subclinical hyperthyroid, and 71.4% of clinical hyperthyroid participants were undiagnosed. […] Our current study showed that a high proportion of thyroid dysfunction remained undiagnosed (as much as 92.6% subclinical hypothyroid, 93.9% clinical hypothyroid, 83% subclinical hyperthyroid, and 71.4% clinical hyperthyroid participants). Another important finding is the high prevalence of hypothyroidism among Croatians.

• #32 How common is thyroid storm and which groups have the highest rates of death from this condition?

  https://www.thyroid.org/patient-thyroid-information/ct-for-patients/september-2023/vol-16-issue-9-p-12-13/

  HYPERTHYROIDISM How common is thyroid storm and which groups have the highest rates of death from this condition? […] Thyroid Storm is the most severe form of hyperthyroidism. […] So far, only 3 research studies have looked into the epidemiology of thyroid storm, and they estimate an incidence of 0.20 to 0.76 cases per 100,000 people per year. […] The estimated occurrence of thyroid storm was 1.4 cases per 100,000 people per year in females and 0.7 cases per 100,000 people per year in males. […] The death rate for females in this age group was 10.9%, and for males, it was even higher at 16.7%. […] This is the first study reporting population-based data on diagnosis and death rate of thyroid storm in Germany. […] However, the diagnosis rate strongly varies with age and sex since the rate of thyroid storm was two times higher in females than in males and it was 3 times higher in persons 60 years compared with younger individuals. […] Thus it is important that doctors become more aware and skilled at diagnosing thyroid storm, especially in a hospital setting.

• #33 How common is thyroid storm and which groups have the highest rates of death from this condition?

  https://www.thyroid.org/patient-thyroid-information/ct-for-patients/september-2023/vol-16-issue-9-p-12-13/

  HYPERTHYROIDISM How common is thyroid storm and which groups have the highest rates of death from this condition? […] Thyroid Storm is the most severe form of hyperthyroidism. […] So far, only 3 research studies have looked into the epidemiology of thyroid storm, and they estimate an incidence of 0.20 to 0.76 cases per 100,000 people per year. […] The estimated occurrence of thyroid storm was 1.4 cases per 100,000 people per year in females and 0.7 cases per 100,000 people per year in males. […] The death rate for females in this age group was 10.9%, and for males, it was even higher at 16.7%. […] This is the first study reporting population-based data on diagnosis and death rate of thyroid storm in Germany. […] However, the diagnosis rate strongly varies with age and sex since the rate of thyroid storm was two times higher in females than in males and it was 3 times higher in persons 60 years compared with younger individuals. […] Thus it is important that doctors become more aware and skilled at diagnosing thyroid storm, especially in a hospital setting.

• #34 How common is thyroid storm and which groups have the highest rates of death from this condition?

  https://www.thyroid.org/patient-thyroid-information/ct-for-patients/september-2023/vol-16-issue-9-p-12-13/

  HYPERTHYROIDISM How common is thyroid storm and which groups have the highest rates of death from this condition? […] Thyroid Storm is the most severe form of hyperthyroidism. […] So far, only 3 research studies have looked into the epidemiology of thyroid storm, and they estimate an incidence of 0.20 to 0.76 cases per 100,000 people per year. […] The estimated occurrence of thyroid storm was 1.4 cases per 100,000 people per year in females and 0.7 cases per 100,000 people per year in males. […] The death rate for females in this age group was 10.9%, and for males, it was even higher at 16.7%. […] This is the first study reporting population-based data on diagnosis and death rate of thyroid storm in Germany. […] However, the diagnosis rate strongly varies with age and sex since the rate of thyroid storm was two times higher in females than in males and it was 3 times higher in persons 60 years compared with younger individuals. […] Thus it is important that doctors become more aware and skilled at diagnosing thyroid storm, especially in a hospital setting.

• #35 How common is thyroid storm and which groups have the highest rates of death from this condition?

  https://www.thyroid.org/patient-thyroid-information/ct-for-patients/september-2023/vol-16-issue-9-p-12-13/

  HYPERTHYROIDISM How common is thyroid storm and which groups have the highest rates of death from this condition? […] Thyroid Storm is the most severe form of hyperthyroidism. […] So far, only 3 research studies have looked into the epidemiology of thyroid storm, and they estimate an incidence of 0.20 to 0.76 cases per 100,000 people per year. […] The estimated occurrence of thyroid storm was 1.4 cases per 100,000 people per year in females and 0.7 cases per 100,000 people per year in males. […] The death rate for females in this age group was 10.9%, and for males, it was even higher at 16.7%. […] This is the first study reporting population-based data on diagnosis and death rate of thyroid storm in Germany. […] However, the diagnosis rate strongly varies with age and sex since the rate of thyroid storm was two times higher in females than in males and it was 3 times higher in persons 60 years compared with younger individuals. […] Thus it is important that doctors become more aware and skilled at diagnosing thyroid storm, especially in a hospital setting.

• #36 How common is thyroid storm and which groups have the highest rates of death from this condition?

  https://www.thyroid.org/patient-thyroid-information/ct-for-patients/september-2023/vol-16-issue-9-p-12-13/

  HYPERTHYROIDISM How common is thyroid storm and which groups have the highest rates of death from this condition? […] Thyroid Storm is the most severe form of hyperthyroidism. […] So far, only 3 research studies have looked into the epidemiology of thyroid storm, and they estimate an incidence of 0.20 to 0.76 cases per 100,000 people per year. […] The estimated occurrence of thyroid storm was 1.4 cases per 100,000 people per year in females and 0.7 cases per 100,000 people per year in males. […] The death rate for females in this age group was 10.9%, and for males, it was even higher at 16.7%. […] This is the first study reporting population-based data on diagnosis and death rate of thyroid storm in Germany. […] However, the diagnosis rate strongly varies with age and sex since the rate of thyroid storm was two times higher in females than in males and it was 3 times higher in persons 60 years compared with younger individuals. […] Thus it is important that doctors become more aware and skilled at diagnosing thyroid storm, especially in a hospital setting.

• #37 Hyperthyroidism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK537053/

  Hyperthyroidism is a common thyroid disorder with multiple underlying etiologies. This disease is characterized by excess thyroid hormone production. Hyperthyroidism is associated with significant short-term and long-term morbidity. Therefore, early recognition of this condition and timely instruction of appropriate therapy is critical. […] The prevalence of hyperthyroidism varies worldwide, based on dietary iodine content. Hyperthyroidism is more common in women compared to men. Other risk factors associated with the development of hyperthyroidism include smoking, iodine deficiency, iodine excess, selenium deficiency, genetic factors, and the use of certain drugs. Graves disease is typically seen in younger patients and is the most common cause of hyperthyroidism in this demographic. The incidence of Graves disease is highest between the age group of 30 to 50 years.

• #38 Hyperthyroidism | Graves’ Disease | Overactive Thyroid | MedlinePlus

  https://medlineplus.gov/hyperthyroidism.html

  Hyperthyroidism, or overactive thyroid, happens when your thyroid gland makes more thyroid hormones than your body needs. […] Hyperthyroidism has several causes. They include: Graves’ disease, an autoimmune disorder in which your immune system attacks your thyroid and causes it to make too much hormone. This is the most common cause. […] You are at higher risk for hyperthyroidism if you: Are a woman, Are older than age 60, Have been pregnant or had a baby within the past 6 months, Have had thyroid surgery or a thyroid problem, such as goiter, Have a family history of thyroid disease. […] If hyperthyroidism isn’t treated, it can cause some serious health problems, including: An irregular heartbeat that can lead to blood clots, stroke, heart failure, and other heart problems, An eye disease called Graves’ ophthalmopathy.

• #39 Hyperthyroidism | Graves’ Disease | Overactive Thyroid | MedlinePlus

  https://medlineplus.gov/hyperthyroidism.html

  Hyperthyroidism, or overactive thyroid, happens when your thyroid gland makes more thyroid hormones than your body needs. […] Hyperthyroidism has several causes. They include: Graves’ disease, an autoimmune disorder in which your immune system attacks your thyroid and causes it to make too much hormone. This is the most common cause. […] You are at higher risk for hyperthyroidism if you: Are a woman, Are older than age 60, Have been pregnant or had a baby within the past 6 months, Have had thyroid surgery or a thyroid problem, such as goiter, Have a family history of thyroid disease. […] If hyperthyroidism isn’t treated, it can cause some serious health problems, including: An irregular heartbeat that can lead to blood clots, stroke, heart failure, and other heart problems, An eye disease called Graves’ ophthalmopathy.

• #40 Hyperthyroidism – Wikipedia

  https://en.wikipedia.org/wiki/Hyperthyroidism

  In the United States hyperthyroidism affects about 1.2% of the population. […] It occurs between two and ten times more often in women. […] The disease is more common in those over the age of 60 years. […] Subclinical hyperthyroidism modestly increases the risk of cognitive impairment and dementia.

• #41 Hyperthyroidism | Graves’ Disease | Overactive Thyroid | MedlinePlus

  https://medlineplus.gov/hyperthyroidism.html

  Hyperthyroidism, or overactive thyroid, happens when your thyroid gland makes more thyroid hormones than your body needs. […] Hyperthyroidism has several causes. They include: Graves’ disease, an autoimmune disorder in which your immune system attacks your thyroid and causes it to make too much hormone. This is the most common cause. […] You are at higher risk for hyperthyroidism if you: Are a woman, Are older than age 60, Have been pregnant or had a baby within the past 6 months, Have had thyroid surgery or a thyroid problem, such as goiter, Have a family history of thyroid disease. […] If hyperthyroidism isn’t treated, it can cause some serious health problems, including: An irregular heartbeat that can lead to blood clots, stroke, heart failure, and other heart problems, An eye disease called Graves’ ophthalmopathy.

• #42 Thyroid disease

  https://womenshealth.gov/a-z-topics/thyroid-disease

  Hyperthyroidism, (hy-pur-THY-roi-diz-uhm) or overactive thyroid, causes your thyroid to make more thyroid hormone than your body needs. This speeds up many of your body’s functions, like your metabolism and heart rate. […] The most common cause of hyperthyroidism is Graves’ disease. Graves’ disease is a problem with the immune system. […] Hyperthyroidism raises your risk for osteoporosis, a condition that causes weak bones that break easily. In fact, hyperthyroidism might affect your bones before you have any of the other symptoms of the condition. This is especially true of women who have gone through menopause or who are already at high risk of osteoporosis. […] Your doctor’s choice of treatment will depend on your symptoms and the cause of your hyperthyroidism. Treatments include:

• #43 Understanding Hyperthyroidism ( Overactive Thyroid Gland ): Causes, Symptoms, and Treatment Options | The American Journal of Patient Health Info

  https://ajphi.org/ajphi/article/view/38

  Hyperthyroidism occurs when you have an excess amount of thyroid hormone produced by your thyroid gland. […] The most common cause of hyperthyroidism is Graves disease. It is an autoimmune condition where the body produces antibodies that stimulate the thyroid. […] Graves disease (GD) is the most common cause of hyperthyroidism in developed countries. It is more commonly seen between people of 30 and 60 years, with 5-10 times increased frequency in women. About 79% of the people are genetically predisposed, and about 21% of them have some environmental factors as a risk factor. […] Hyperthyroidism can potentially impact fertility in both men and women. However, the extent of its effects can vary depending on factors such as the severity of the condition and how well it is managed. […] Hyperthyroidism can develop during pregnancy due to changes in hormone levels and immune function. This condition is known as gestational transient thyrotoxicosis and typically resolves after childbirth.

• #44 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  Iodine intake has a U-shaped relationship with thyroid disorders. Historically, regions with iodine deficiency saw more hyperthyroidism in older adults (due to nodular goiters), especially after iodization programs (a phenomenon where sudden iodine repletion “wakes up” overactive thyroid nodules). Now, sustained iodine supplementation is causing a long-term decrease in those cases. In formerly deficient areas, overt hyperthyroidism from toxic nodular goiter has diminished over time as goiter rates fall. Conversely, very high iodine intake (as seen in some coastal regions with kelp-rich diets) can slightly increase autoimmune thyroid disease, but studies in China and Japan did not find major differences in hyperthyroid rates between iodine-sufficient vs. high-excess areas. Overall, iodine sufficiency programs have reduced hyperthyroid incidence in many parts of the world, a public health success.

• #45 Hyperthyroidism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK537053/

  Hyperthyroidism is a common thyroid disorder with multiple underlying etiologies. This disease is characterized by excess thyroid hormone production. Hyperthyroidism is associated with significant short-term and long-term morbidity. Therefore, early recognition of this condition and timely instruction of appropriate therapy is critical. […] The prevalence of hyperthyroidism varies worldwide, based on dietary iodine content. Hyperthyroidism is more common in women compared to men. Other risk factors associated with the development of hyperthyroidism include smoking, iodine deficiency, iodine excess, selenium deficiency, genetic factors, and the use of certain drugs. Graves disease is typically seen in younger patients and is the most common cause of hyperthyroidism in this demographic. The incidence of Graves disease is highest between the age group of 30 to 50 years.

• #46 Hyperthyroidism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK537053/

  Hyperthyroidism is a common thyroid disorder with multiple underlying etiologies. This disease is characterized by excess thyroid hormone production. Hyperthyroidism is associated with significant short-term and long-term morbidity. Therefore, early recognition of this condition and timely instruction of appropriate therapy is critical. […] The prevalence of hyperthyroidism varies worldwide, based on dietary iodine content. Hyperthyroidism is more common in women compared to men. Other risk factors associated with the development of hyperthyroidism include smoking, iodine deficiency, iodine excess, selenium deficiency, genetic factors, and the use of certain drugs. Graves disease is typically seen in younger patients and is the most common cause of hyperthyroidism in this demographic. The incidence of Graves disease is highest between the age group of 30 to 50 years.

• #47 Hyperthyroidism

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5014602/

  Prevalence of hyperthyroidism is 08% in Europe, and 13% in the USA. Hyperthyroidism increases with age and is more frequent in women. The prevalence of overt hyperthyroidism is 0508% in Europe, and 05% in the USA. […] Data for ethnic differences are scarce, but hyperthyroidism seems to be slightly more frequent in white people than in other races. The incidence of mild hyperthyroidism is also reported to be higher in iodine-deficient areas than in iodine-sufficient areas, and to decrease after introduction of universal salt iodisation programmes.

• #48 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  Iodine intake has a U-shaped relationship with thyroid disorders. Historically, regions with iodine deficiency saw more hyperthyroidism in older adults (due to nodular goiters), especially after iodization programs (a phenomenon where sudden iodine repletion “wakes up” overactive thyroid nodules). Now, sustained iodine supplementation is causing a long-term decrease in those cases. In formerly deficient areas, overt hyperthyroidism from toxic nodular goiter has diminished over time as goiter rates fall. Conversely, very high iodine intake (as seen in some coastal regions with kelp-rich diets) can slightly increase autoimmune thyroid disease, but studies in China and Japan did not find major differences in hyperthyroid rates between iodine-sufficient vs. high-excess areas. Overall, iodine sufficiency programs have reduced hyperthyroid incidence in many parts of the world, a public health success.

• #49 Hyperthyroidism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK537053/

  Hyperthyroidism is a common thyroid disorder with multiple underlying etiologies. This disease is characterized by excess thyroid hormone production. Hyperthyroidism is associated with significant short-term and long-term morbidity. Therefore, early recognition of this condition and timely instruction of appropriate therapy is critical. […] The prevalence of hyperthyroidism varies worldwide, based on dietary iodine content. Hyperthyroidism is more common in women compared to men. Other risk factors associated with the development of hyperthyroidism include smoking, iodine deficiency, iodine excess, selenium deficiency, genetic factors, and the use of certain drugs. Graves disease is typically seen in younger patients and is the most common cause of hyperthyroidism in this demographic. The incidence of Graves disease is highest between the age group of 30 to 50 years.

• #50 Hyperthyroidism – Life Extension

  https://www.lifeextension.com/protocols/metabolic-health/hyperthyroidism?srsltid=AfmBOopl42gyMSoAbsDdrhnGLrWwvzyNXgFttelhL1x8dKSQ4EfyIMwE

  Up to 1% of the global population has hyperthyroidism, or overactive thyroid, which can contribute to troublesome symptoms like unintentional weight loss, nervousness, and sleep disturbances. An enlarged thyroid, known a a goiter, may also occur in some people. […] Hyperthyroidism affects about 1.3% of the U.S. population (0.5% clinical and 0.7% subclinical). […] An estimated 20 million Americans have some form of thyroid disease. Globally, up to 1% of the population has hyperthyroidism. […] Risk factors for hyperthyroidism include family history, female gender, and having certain medical conditions such as type 1 diabetes and adrenal insufficiency. In addition, emotional or physical stress, pregnancy, smoking, and being under 40 increase the risk of Graves disease, the number one cause of hyperthyroidism.

• #51 Hyperthyroidism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK537053/

  Hyperthyroidism is a common thyroid disorder with multiple underlying etiologies. This disease is characterized by excess thyroid hormone production. Hyperthyroidism is associated with significant short-term and long-term morbidity. Therefore, early recognition of this condition and timely instruction of appropriate therapy is critical. […] The prevalence of hyperthyroidism varies worldwide, based on dietary iodine content. Hyperthyroidism is more common in women compared to men. Other risk factors associated with the development of hyperthyroidism include smoking, iodine deficiency, iodine excess, selenium deficiency, genetic factors, and the use of certain drugs. Graves disease is typically seen in younger patients and is the most common cause of hyperthyroidism in this demographic. The incidence of Graves disease is highest between the age group of 30 to 50 years.

• #52 Hyperthyroidism | Graves’ Disease | Overactive Thyroid | MedlinePlus

  https://medlineplus.gov/hyperthyroidism.html

  Hyperthyroidism, or overactive thyroid, happens when your thyroid gland makes more thyroid hormones than your body needs. […] Hyperthyroidism has several causes. They include: Graves’ disease, an autoimmune disorder in which your immune system attacks your thyroid and causes it to make too much hormone. This is the most common cause. […] You are at higher risk for hyperthyroidism if you: Are a woman, Are older than age 60, Have been pregnant or had a baby within the past 6 months, Have had thyroid surgery or a thyroid problem, such as goiter, Have a family history of thyroid disease. […] If hyperthyroidism isn’t treated, it can cause some serious health problems, including: An irregular heartbeat that can lead to blood clots, stroke, heart failure, and other heart problems, An eye disease called Graves’ ophthalmopathy.

• #53 Graves’ disease: MedlinePlus GeneticsLock

  https://medlineplus.gov/genetics/condition/graves-disease/

  Graves’ disease affects about 1 in 200 people. The disease occurs more often in women than in men, which may be related to hormonal factors. Graves’ disease is the most common cause of thyroid overactivity (hyperthyroidism) in the United States. […] Graves’ disease is classified as an autoimmune disorder, one of a large group of conditions that occur when the immune system attacks the body’s own tissues and organs. In people with Graves’ disease, the immune system creates a protein (antibody) called thyroid-stimulating immunoglobulin (TSI). TSI signals the thyroid to increase its production of hormones abnormally. The resulting overactivity of the thyroid causes many of the signs and symptoms of Graves’ disease. […] People with Graves’ disease have an increased risk of developing other autoimmune disorders, including rheumatoid arthritis, pernicious anemia, systemic lupus erythematosus, Addison disease, celiac disease, type 1 diabetes, and vitiligo.

• #54 Hyperthyroidism – Life Extension

  https://www.lifeextension.com/protocols/metabolic-health/hyperthyroidism?srsltid=AfmBOopl42gyMSoAbsDdrhnGLrWwvzyNXgFttelhL1x8dKSQ4EfyIMwE

  Up to 1% of the global population has hyperthyroidism, or overactive thyroid, which can contribute to troublesome symptoms like unintentional weight loss, nervousness, and sleep disturbances. An enlarged thyroid, known a a goiter, may also occur in some people. […] Hyperthyroidism affects about 1.3% of the U.S. population (0.5% clinical and 0.7% subclinical). […] An estimated 20 million Americans have some form of thyroid disease. Globally, up to 1% of the population has hyperthyroidism. […] Risk factors for hyperthyroidism include family history, female gender, and having certain medical conditions such as type 1 diabetes and adrenal insufficiency. In addition, emotional or physical stress, pregnancy, smoking, and being under 40 increase the risk of Graves disease, the number one cause of hyperthyroidism.

• #55 Hyperthyroidism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK537053/

  The 1977 Whickham Survey evaluated the spectrum of thyroid disorders in County Durham in northeastern England. The Whickham Survey demonstrated a prevalence of hyperthyroidism in women, approximately 10 times more than that of men (2.7% versus 0.23%). The prevalence of hyperthyroidism in the United States was 1.3% in the general population, with 0.5% cases of overt hyperthyroidism and 0.7% cases of subclinical hyperthyroidism. A meta-analysis found the prevalence of hyperthyroidism in Europe to be 0.75%. The prevalence of overt hyperthyroidism is similar in China at 0.78%. Amiodarone-induced thyrotoxicosis (AIT) is seen in about 6% of the individuals taking the medication in iodine-sufficient areas and about 10% in individuals taking the medication from iodine-deficient areas.

• #56 Hyperthyroidism

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5014602/

  Prevalence of hyperthyroidism is 08% in Europe, and 13% in the USA. Hyperthyroidism increases with age and is more frequent in women. The prevalence of overt hyperthyroidism is 0508% in Europe, and 05% in the USA. […] Data for ethnic differences are scarce, but hyperthyroidism seems to be slightly more frequent in white people than in other races. The incidence of mild hyperthyroidism is also reported to be higher in iodine-deficient areas than in iodine-sufficient areas, and to decrease after introduction of universal salt iodisation programmes.

• #57 Hyperthyroidism

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5014602/

  Prevalence of hyperthyroidism is 08% in Europe, and 13% in the USA. Hyperthyroidism increases with age and is more frequent in women. The prevalence of overt hyperthyroidism is 0508% in Europe, and 05% in the USA. […] Data for ethnic differences are scarce, but hyperthyroidism seems to be slightly more frequent in white people than in other races. The incidence of mild hyperthyroidism is also reported to be higher in iodine-deficient areas than in iodine-sufficient areas, and to decrease after introduction of universal salt iodisation programmes.

• #58 Thyroid Disorders, Active Component, U.S. Armed Forces, 2008–2017 | Health.mil

  https://health.mil/News/Articles/2018/12/01/Thyroid-Disorders?page=3

  This analysis describes the incidence and prevalence of five thyroid disorders (goiter, thyrotoxicosis, primary/not otherwise specified [NOS] hypothyroidism, thyroiditis, and other disorders of the thyroid) among active component service members between 2008 and 2017. […] The prevalence of hyperthyroidism in the U.S. is estimated to be 1.3% according to data from the NHANES-III, with the lowest prevalence observed among Mexican Americans and the highest among non-Hispanic whites. Hyperthyroidism can lead to thyrotoxicosis, a term that refers to having an excess of thyroid hormone in the body from any cause. […] Although thyroid disorders are treatable, hypothyroidism and hyperthyroidism can result in periods of non-deployability, temporary duty profile, or need for medical waiver at the time of diagnosis or if there is a disruption in treatment. More severe cases of hyperthyroidism can take up to 1 year to stabilize, resulting in significant periods of limited deployability. […] In contrast with a previous MSMR report documenting increases in thyroid disorder diagnoses among active component service members between 2002 and 2011, the results of the current analysis indicate that the incidence of thyroid disorders remained stable or decreased between 2008 and 2017.

• #59 Hyperthyroidism and Thyrotoxicosis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/767130-overview

  Graves disease is the most common form of hyperthyroidism in the United States, causing approximately 60-80% of cases of thyrotoxicosis. The annual incidence of Graves disease was found to be 0.5 cases per 1000 population during a 20-year period, with the peak occurrence in people aged 20-40 years. […] Toxic multinodular goiter (15-20% of thyrotoxicosis) occurs more frequently in regions of iodine deficiency. Most persons in the United States receive sufficient iodine, and the incidence of toxic multinodular goiter in the US population is lower than that in areas of the world with iodine deficiency. Toxic adenoma is the cause of 3-5% of cases of thyrotoxicosis. […] The incidences of Graves disease and toxic multinodular goiter change with iodine intake. Compared with regions of the world with less iodine intake, the United States has more cases of Graves disease and fewer cases of toxic multinodular goiters.

• #60 Hyperthyroidism and Thyrotoxicosis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/767130-overview

  Graves disease is the most common form of hyperthyroidism in the United States, causing approximately 60-80% of cases of thyrotoxicosis. The annual incidence of Graves disease was found to be 0.5 cases per 1000 population during a 20-year period, with the peak occurrence in people aged 20-40 years. […] Toxic multinodular goiter (15-20% of thyrotoxicosis) occurs more frequently in regions of iodine deficiency. Most persons in the United States receive sufficient iodine, and the incidence of toxic multinodular goiter in the US population is lower than that in areas of the world with iodine deficiency. Toxic adenoma is the cause of 3-5% of cases of thyrotoxicosis. […] The incidences of Graves disease and toxic multinodular goiter change with iodine intake. Compared with regions of the world with less iodine intake, the United States has more cases of Graves disease and fewer cases of toxic multinodular goiters.

• #61 Hyperthyroidism and Thyrotoxicosis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/767130-overview

  Graves disease is the most common form of hyperthyroidism in the United States, causing approximately 60-80% of cases of thyrotoxicosis. The annual incidence of Graves disease was found to be 0.5 cases per 1000 population during a 20-year period, with the peak occurrence in people aged 20-40 years. […] Toxic multinodular goiter (15-20% of thyrotoxicosis) occurs more frequently in regions of iodine deficiency. Most persons in the United States receive sufficient iodine, and the incidence of toxic multinodular goiter in the US population is lower than that in areas of the world with iodine deficiency. Toxic adenoma is the cause of 3-5% of cases of thyrotoxicosis. […] The incidences of Graves disease and toxic multinodular goiter change with iodine intake. Compared with regions of the world with less iodine intake, the United States has more cases of Graves disease and fewer cases of toxic multinodular goiters.

• #62 Disorders that cause hyperthyroidism – UpToDate

  https://www.uptodate.com/contents/disorders-that-cause-hyperthyroidism

  Several different disorders can cause hyperthyroidism. It is essential that the correct cause be identified because appropriate therapy depends upon the underlying mechanism of the hyperthyroidism. […] The global prevalence of hyperthyroidism is 0.2 to 1.4 percent. In the United States, the overall prevalence of hyperthyroidism is approximately 1.3 percent, and it increases to 4 to 5 percent in older women. Hyperthyroidism is more common in women than men (5:1 ratio), and in smokers. Graves’ disease is seen most often in younger women and in regions of iodine sufficiency, while toxic nodular goiter is more common in older women and in regions of mild to moderate iodine deficiency.

• #63 Subclinical Hyperthyroidism: When to Consider Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2017/0601/p710.html

  Subclinical hyperthyroidism is defined by a low or undetectable serum thyroid-stimulating hormone level, with normal free thyroxine and total or free triiodothyronine levels. The prevalence of subclinical hyperthyroidism in the general population is about 1% to 2%; however, it may be higher in iodine-deficient areas. […] The prevalence of endogenous subclinical hyperthyroidism can be as high as 15% in patients older than 70 years who live in iodine-deficient regions. […] Subclinical hyperthyroidism is most common in patients receiving thyroid hormone replacement therapy; the prevalence in these patients may be as high as 20%, particularly in those taking desiccated thyroid hormone. […] A large Danish retrospective population-based study found that subclinical hyperthyroidism is associated with increased all-cause mortality and major adverse cardiovascular events, with heart failure as the leading cause of increased cardiovascular mortality. […] The highest risk was observed in patients with TSH levels less than 0.1 mIU per L, in men, and in adults older than 65 years.

• #64 Disorders that cause hyperthyroidism – UpToDate

  https://www.uptodate.com/contents/disorders-that-cause-hyperthyroidism

  Several different disorders can cause hyperthyroidism. It is essential that the correct cause be identified because appropriate therapy depends upon the underlying mechanism of the hyperthyroidism. […] The global prevalence of hyperthyroidism is 0.2 to 1.4 percent. In the United States, the overall prevalence of hyperthyroidism is approximately 1.3 percent, and it increases to 4 to 5 percent in older women. Hyperthyroidism is more common in women than men (5:1 ratio), and in smokers. Graves’ disease is seen most often in younger women and in regions of iodine sufficiency, while toxic nodular goiter is more common in older women and in regions of mild to moderate iodine deficiency.

• #65 Hyperthyroidism and Thyrotoxicosis: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/767130-overview

  Graves disease is the most common form of hyperthyroidism in the United States, causing approximately 60-80% of cases of thyrotoxicosis. The annual incidence of Graves disease was found to be 0.5 cases per 1000 population during a 20-year period, with the peak occurrence in people aged 20-40 years. […] Toxic multinodular goiter (15-20% of thyrotoxicosis) occurs more frequently in regions of iodine deficiency. Most persons in the United States receive sufficient iodine, and the incidence of toxic multinodular goiter in the US population is lower than that in areas of the world with iodine deficiency. Toxic adenoma is the cause of 3-5% of cases of thyrotoxicosis. […] The incidences of Graves disease and toxic multinodular goiter change with iodine intake. Compared with regions of the world with less iodine intake, the United States has more cases of Graves disease and fewer cases of toxic multinodular goiters.

• #66 Hyperthyroidism (overactive thyroid) | Doctor

  https://patient.info/doctor/hyperthyroidism

  Hyperthyroidism is overactivity of the thyroid gland, which results in a number of symptoms and signs. It can be primary or secondary: […] In Europe, thyrotoxicosis affects around 1 in 2,000 people annually. There is a global prevalence of 0.2 – 2.5%. Thyrotoxicosis is still under-diagnosed however – it has been shown that in people older than 65 years, undiagnosed hyperthyroidism occurs in 0.3% of people and around 2% of people aged over 65 years have subclinical hyperthyroidism. Graves’ disease in adults affects approximately 2% of women and 0.2% of men. Graves’ disease accounts for around 75% of cases. […] Subclinical hyperthyroidism occurs in around 2% of the elderly population. The most common cause of true subclinical hyperthyroidism is toxic nodular goitre, especially in the elderly. Subclinical hyperthyroidism is associated with increased risks of coronary heart disease (CHD) mortality and incident atrial fibrillation, with highest risks of CHD mortality and atrial fibrillation when thyrotropin level is lower than 0.10 mIU/L. Subclinical hyperthyroidism is also associated with an increased risk of hip and other fractures, particularly among those with TSH levels of less than 0.10 mIU/L.

• #67 Hyperthyroidism: Diagnosis and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2016/0301/p363.html

  Hyperthyroidism is an excessive concentration of thyroid hormones in tissues caused by increased synthesis of thyroid hormones, excessive release of preformed thyroid hormones, or an endogenous or exogenous extrathyroidal source. The most common causes of an excessive production of thyroid hormones are Graves disease, toxic multinodular goiter, and toxic adenoma. The most common cause of an excessive passive release of thyroid hormones is painless (silent) thyroiditis, although its clinical presentation is the same as with other causes. Hyperthyroidism caused by overproduction of thyroid hormones can be treated with antithyroid medications (methimazole and propylthiouracil), radioactive iodine ablation of the thyroid gland, or surgical thyroidectomy. Radioactive iodine ablation is the most widely used treatment in the United States. The choice of treatment depends on the underlying diagnosis, the presence of contraindications to a particular treatment modality, the severity of hyperthyroidism, and the patient’s preference.

• #68 Hyperthyroidism – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK537053/

  The 1977 Whickham Survey evaluated the spectrum of thyroid disorders in County Durham in northeastern England. The Whickham Survey demonstrated a prevalence of hyperthyroidism in women, approximately 10 times more than that of men (2.7% versus 0.23%). The prevalence of hyperthyroidism in the United States was 1.3% in the general population, with 0.5% cases of overt hyperthyroidism and 0.7% cases of subclinical hyperthyroidism. A meta-analysis found the prevalence of hyperthyroidism in Europe to be 0.75%. The prevalence of overt hyperthyroidism is similar in China at 0.78%. Amiodarone-induced thyrotoxicosis (AIT) is seen in about 6% of the individuals taking the medication in iodine-sufficient areas and about 10% in individuals taking the medication from iodine-deficient areas.

• #69 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  Annual Incidence: New cases of hyperthyroidism occur at an annual rate of roughly 20–50 per 100,000 people in iodine-sufficient populations. Graves’ disease (autoimmune hyperthyroidism) has an incidence around 0.5 cases per 1,000 per year (i.e. 50 per 100,000) in the general population, with peaks in younger adults. A large study in Italy found an overall hyperthyroidism incidence of 54 per 100,000 person-years. In Europe, the average incidence is reported around 51 per 100,000 per year. These rates indicate that for every 100,000 people, roughly 50 will be diagnosed with hyperthyroidism each year. Subclinical hyperthyroidism is more frequently detected: it affects an additional 1–2% of people per year in some cohorts, though many cases may be transient or mild. […] Historical Trends: The incidence and hospitalization rates for hyperthyroidism have shown some declines in recent decades, likely due to better iodine nutrition and improved outpatient management. For example, in the iodine-deficient Veneto region of Italy, the introduction of salt iodization since 2005 led to a significant drop in new hyperthyroidism cases, especially those due to nodular goiter. Similarly, in the U.S., hospitalizations for hyperthyroidism fell by 28% from 2008 to 2018 (from 12,689 to 9,110 annual hospital stays). This likely reflects earlier diagnosis and treatment on an outpatient basis, preventing severe cases that require admission.

• #70 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  Annual Incidence: New cases of hyperthyroidism occur at an annual rate of roughly 20–50 per 100,000 people in iodine-sufficient populations. Graves’ disease (autoimmune hyperthyroidism) has an incidence around 0.5 cases per 1,000 per year (i.e. 50 per 100,000) in the general population, with peaks in younger adults. A large study in Italy found an overall hyperthyroidism incidence of 54 per 100,000 person-years. In Europe, the average incidence is reported around 51 per 100,000 per year. These rates indicate that for every 100,000 people, roughly 50 will be diagnosed with hyperthyroidism each year. Subclinical hyperthyroidism is more frequently detected: it affects an additional 1–2% of people per year in some cohorts, though many cases may be transient or mild. […] Historical Trends: The incidence and hospitalization rates for hyperthyroidism have shown some declines in recent decades, likely due to better iodine nutrition and improved outpatient management. For example, in the iodine-deficient Veneto region of Italy, the introduction of salt iodization since 2005 led to a significant drop in new hyperthyroidism cases, especially those due to nodular goiter. Similarly, in the U.S., hospitalizations for hyperthyroidism fell by 28% from 2008 to 2018 (from 12,689 to 9,110 annual hospital stays). This likely reflects earlier diagnosis and treatment on an outpatient basis, preventing severe cases that require admission.

• #71 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  Annual Incidence: New cases of hyperthyroidism occur at an annual rate of roughly 20–50 per 100,000 people in iodine-sufficient populations. Graves’ disease (autoimmune hyperthyroidism) has an incidence around 0.5 cases per 1,000 per year (i.e. 50 per 100,000) in the general population, with peaks in younger adults. A large study in Italy found an overall hyperthyroidism incidence of 54 per 100,000 person-years. In Europe, the average incidence is reported around 51 per 100,000 per year. These rates indicate that for every 100,000 people, roughly 50 will be diagnosed with hyperthyroidism each year. Subclinical hyperthyroidism is more frequently detected: it affects an additional 1–2% of people per year in some cohorts, though many cases may be transient or mild. […] Historical Trends: The incidence and hospitalization rates for hyperthyroidism have shown some declines in recent decades, likely due to better iodine nutrition and improved outpatient management. For example, in the iodine-deficient Veneto region of Italy, the introduction of salt iodization since 2005 led to a significant drop in new hyperthyroidism cases, especially those due to nodular goiter. Similarly, in the U.S., hospitalizations for hyperthyroidism fell by 28% from 2008 to 2018 (from 12,689 to 9,110 annual hospital stays). This likely reflects earlier diagnosis and treatment on an outpatient basis, preventing severe cases that require admission.

• #72 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  Annual Incidence: New cases of hyperthyroidism occur at an annual rate of roughly 20–50 per 100,000 people in iodine-sufficient populations. Graves’ disease (autoimmune hyperthyroidism) has an incidence around 0.5 cases per 1,000 per year (i.e. 50 per 100,000) in the general population, with peaks in younger adults. A large study in Italy found an overall hyperthyroidism incidence of 54 per 100,000 person-years. In Europe, the average incidence is reported around 51 per 100,000 per year. These rates indicate that for every 100,000 people, roughly 50 will be diagnosed with hyperthyroidism each year. Subclinical hyperthyroidism is more frequently detected: it affects an additional 1–2% of people per year in some cohorts, though many cases may be transient or mild. […] Historical Trends: The incidence and hospitalization rates for hyperthyroidism have shown some declines in recent decades, likely due to better iodine nutrition and improved outpatient management. For example, in the iodine-deficient Veneto region of Italy, the introduction of salt iodization since 2005 led to a significant drop in new hyperthyroidism cases, especially those due to nodular goiter. Similarly, in the U.S., hospitalizations for hyperthyroidism fell by 28% from 2008 to 2018 (from 12,689 to 9,110 annual hospital stays). This likely reflects earlier diagnosis and treatment on an outpatient basis, preventing severe cases that require admission.

• #73 Thyroid Disorders, Active Component, U.S. Armed Forces, 2008–2017 | Health.mil

  https://health.mil/News/Articles/2018/12/01/Thyroid-Disorders?page=3

  This analysis describes the incidence and prevalence of five thyroid disorders (goiter, thyrotoxicosis, primary/not otherwise specified [NOS] hypothyroidism, thyroiditis, and other disorders of the thyroid) among active component service members between 2008 and 2017. […] The prevalence of hyperthyroidism in the U.S. is estimated to be 1.3% according to data from the NHANES-III, with the lowest prevalence observed among Mexican Americans and the highest among non-Hispanic whites. Hyperthyroidism can lead to thyrotoxicosis, a term that refers to having an excess of thyroid hormone in the body from any cause. […] Although thyroid disorders are treatable, hypothyroidism and hyperthyroidism can result in periods of non-deployability, temporary duty profile, or need for medical waiver at the time of diagnosis or if there is a disruption in treatment. More severe cases of hyperthyroidism can take up to 1 year to stabilize, resulting in significant periods of limited deployability. […] In contrast with a previous MSMR report documenting increases in thyroid disorder diagnoses among active component service members between 2002 and 2011, the results of the current analysis indicate that the incidence of thyroid disorders remained stable or decreased between 2008 and 2017.

• #74 Thyroid Disorders, Active Component, U.S. Armed Forces, 2008–2017 | Health.mil

  https://health.mil/News/Articles/2018/12/01/Thyroid-Disorders

  This analysis describes the incidence and prevalence of five thyroid disorders (goiter, thyrotoxicosis, primary/not otherwise specified [NOS] hypothyroidism, thyroiditis, and other disorders of the thyroid) among active component service members between 2008 and 2017. […] The prevalence of hyperthyroidism in the U.S. is estimated to be 1.3% according to data from the NHANES-III, with the lowest prevalence observed among Mexican Americans and the highest among non-Hispanic whites. […] Hyperthyroidism and hypothyroidism can significantly degrade the military operational capabilities of affected service members due to the various symptoms of the disorders. […] Although thyroid disorders are treatable, hypothyroidism and hyperthyroidism can result in periods of non-deployability, temporary duty profile, or need for medical waiver at the time of diagnosis or if there is a disruption in treatment. More severe cases of hyperthyroidism can take up to 1 year to stabilize, resulting in significant periods of limited deployability. […] In contrast with a previous MSMR report documenting increases in thyroid disorder diagnoses among active component service members between 2002 and 2011, the results of the current analysis indicate that the incidence of thyroid disorders remained stable or decreased between 2008 and 2017.

• #75 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  With aging populations worldwide, the burden of hyperthyroidism may shift. Because toxic multinodular goiter tends to affect older individuals, an increase in elderly population could keep nodular hyperthyroidism cases significant (though counteracted by iodine supplementation). Meanwhile, the trend toward earlier detection (through routine blood tests) is likely to continue, meaning more cases will be caught at subclinical stages. In advanced economies, the prevalence of undiagnosed thyroid disease has been falling due to widespread screening. Thus, we expect fewer severe, undetected cases in the future, and most patients will receive treatment before complications develop. Some projections suggest that if current trends hold, hospitalizations and crises like thyroid storm will remain rare or decline as outpatient care improves. However, continued vigilance is needed in regions with limited healthcare access – many developing countries still lack comprehensive thyroid epidemiology data, and iodine deficiency or environmental factors could influence future incidence there.

• #76 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  With aging populations worldwide, the burden of hyperthyroidism may shift. Because toxic multinodular goiter tends to affect older individuals, an increase in elderly population could keep nodular hyperthyroidism cases significant (though counteracted by iodine supplementation). Meanwhile, the trend toward earlier detection (through routine blood tests) is likely to continue, meaning more cases will be caught at subclinical stages. In advanced economies, the prevalence of undiagnosed thyroid disease has been falling due to widespread screening. Thus, we expect fewer severe, undetected cases in the future, and most patients will receive treatment before complications develop. Some projections suggest that if current trends hold, hospitalizations and crises like thyroid storm will remain rare or decline as outpatient care improves. However, continued vigilance is needed in regions with limited healthcare access – many developing countries still lack comprehensive thyroid epidemiology data, and iodine deficiency or environmental factors could influence future incidence there.

• #77 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  With aging populations worldwide, the burden of hyperthyroidism may shift. Because toxic multinodular goiter tends to affect older individuals, an increase in elderly population could keep nodular hyperthyroidism cases significant (though counteracted by iodine supplementation). Meanwhile, the trend toward earlier detection (through routine blood tests) is likely to continue, meaning more cases will be caught at subclinical stages. In advanced economies, the prevalence of undiagnosed thyroid disease has been falling due to widespread screening. Thus, we expect fewer severe, undetected cases in the future, and most patients will receive treatment before complications develop. Some projections suggest that if current trends hold, hospitalizations and crises like thyroid storm will remain rare or decline as outpatient care improves. However, continued vigilance is needed in regions with limited healthcare access – many developing countries still lack comprehensive thyroid epidemiology data, and iodine deficiency or environmental factors could influence future incidence there.

• #78 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  With aging populations worldwide, the burden of hyperthyroidism may shift. Because toxic multinodular goiter tends to affect older individuals, an increase in elderly population could keep nodular hyperthyroidism cases significant (though counteracted by iodine supplementation). Meanwhile, the trend toward earlier detection (through routine blood tests) is likely to continue, meaning more cases will be caught at subclinical stages. In advanced economies, the prevalence of undiagnosed thyroid disease has been falling due to widespread screening. Thus, we expect fewer severe, undetected cases in the future, and most patients will receive treatment before complications develop. Some projections suggest that if current trends hold, hospitalizations and crises like thyroid storm will remain rare or decline as outpatient care improves. However, continued vigilance is needed in regions with limited healthcare access – many developing countries still lack comprehensive thyroid epidemiology data, and iodine deficiency or environmental factors could influence future incidence there.

• #79 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  With aging populations worldwide, the burden of hyperthyroidism may shift. Because toxic multinodular goiter tends to affect older individuals, an increase in elderly population could keep nodular hyperthyroidism cases significant (though counteracted by iodine supplementation). Meanwhile, the trend toward earlier detection (through routine blood tests) is likely to continue, meaning more cases will be caught at subclinical stages. In advanced economies, the prevalence of undiagnosed thyroid disease has been falling due to widespread screening. Thus, we expect fewer severe, undetected cases in the future, and most patients will receive treatment before complications develop. Some projections suggest that if current trends hold, hospitalizations and crises like thyroid storm will remain rare or decline as outpatient care improves. However, continued vigilance is needed in regions with limited healthcare access – many developing countries still lack comprehensive thyroid epidemiology data, and iodine deficiency or environmental factors could influence future incidence there.

• #80 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  With aging populations worldwide, the burden of hyperthyroidism may shift. Because toxic multinodular goiter tends to affect older individuals, an increase in elderly population could keep nodular hyperthyroidism cases significant (though counteracted by iodine supplementation). Meanwhile, the trend toward earlier detection (through routine blood tests) is likely to continue, meaning more cases will be caught at subclinical stages. In advanced economies, the prevalence of undiagnosed thyroid disease has been falling due to widespread screening. Thus, we expect fewer severe, undetected cases in the future, and most patients will receive treatment before complications develop. Some projections suggest that if current trends hold, hospitalizations and crises like thyroid storm will remain rare or decline as outpatient care improves. However, continued vigilance is needed in regions with limited healthcare access – many developing countries still lack comprehensive thyroid epidemiology data, and iodine deficiency or environmental factors could influence future incidence there.

• #81 Hyperthyroidism (overactive thyroid) | Doctor

  https://patient.info/doctor/hyperthyroidism

  Hyperthyroidism is overactivity of the thyroid gland, which results in a number of symptoms and signs. It can be primary or secondary: […] In Europe, thyrotoxicosis affects around 1 in 2,000 people annually. There is a global prevalence of 0.2 – 2.5%. Thyrotoxicosis is still under-diagnosed however – it has been shown that in people older than 65 years, undiagnosed hyperthyroidism occurs in 0.3% of people and around 2% of people aged over 65 years have subclinical hyperthyroidism. Graves’ disease in adults affects approximately 2% of women and 0.2% of men. Graves’ disease accounts for around 75% of cases. […] Subclinical hyperthyroidism occurs in around 2% of the elderly population. The most common cause of true subclinical hyperthyroidism is toxic nodular goitre, especially in the elderly. Subclinical hyperthyroidism is associated with increased risks of coronary heart disease (CHD) mortality and incident atrial fibrillation, with highest risks of CHD mortality and atrial fibrillation when thyrotropin level is lower than 0.10 mIU/L. Subclinical hyperthyroidism is also associated with an increased risk of hip and other fractures, particularly among those with TSH levels of less than 0.10 mIU/L.

• #82 Hyperthyroidism (overactive thyroid) | Doctor

  https://patient.info/doctor/hyperthyroidism

  Hyperthyroidism is overactivity of the thyroid gland, which results in a number of symptoms and signs. It can be primary or secondary: […] In Europe, thyrotoxicosis affects around 1 in 2,000 people annually. There is a global prevalence of 0.2 – 2.5%. Thyrotoxicosis is still under-diagnosed however – it has been shown that in people older than 65 years, undiagnosed hyperthyroidism occurs in 0.3% of people and around 2% of people aged over 65 years have subclinical hyperthyroidism. Graves’ disease in adults affects approximately 2% of women and 0.2% of men. Graves’ disease accounts for around 75% of cases. […] Subclinical hyperthyroidism occurs in around 2% of the elderly population. The most common cause of true subclinical hyperthyroidism is toxic nodular goitre, especially in the elderly. Subclinical hyperthyroidism is associated with increased risks of coronary heart disease (CHD) mortality and incident atrial fibrillation, with highest risks of CHD mortality and atrial fibrillation when thyrotropin level is lower than 0.10 mIU/L. Subclinical hyperthyroidism is also associated with an increased risk of hip and other fractures, particularly among those with TSH levels of less than 0.10 mIU/L.

• #83

  https://www.nhs.uk/conditions/overactive-thyroid-hyperthyroidism/complications/

  Several complications can develop if you have an overactive thyroid (hyperthyroidism), particularly if the condition is not treated. […] Eye problems, known as thyroid eye disease or Graves’ ophthalmopathy, affect around 1 in 4 people with an overactive thyroid caused by Graves’ disease. […] If you have an overactive thyroid during pregnancy and your condition is not well controlled, it can increase the risk of: pre-eclampsia, miscarriage, premature labour and birth (before the 37th week of pregnancy), your baby having a low birthweight. […] Rarely, an undiagnosed or poorly controlled overactive thyroid can lead to a serious, life-threatening condition called a thyroid storm. […] An overactive thyroid can also increase your chances of developing: atrial fibrillation a heart condition that causes an irregular and often abnormally fast heart rate, weakened bones (osteoporosis) a condition that makes your bones fragile and more likely to break, heart failure where the heart is unable to pump blood around your body properly.

• #84 Hyperthyroidism (Overactive Thyroid): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/14129-hyperthyroidism

  Hyperthyroidism, also called overactive thyroid, happens when your thyroid makes and releases high levels of thyroid hormone. Hyperthyroidism is relatively rare. Approximately 1.3% of people in the United States have it. […] Hyperthyroidism is a treatable condition. Most people do well with treatment. […] Complications from untreated or undertreated hyperthyroidism include: Atrial fibrillation (Afib), Congestive heart failure, Infertility, Ischemic stroke, Osteoporosis. […] A rare and life-threatening complication of hyperthyroidism is thyroid storm (thyroid crisis or thyrotoxic crisis). It happens when your thyroid makes and releases a large amount of thyroid hormone in a short amount of time.

• #85 Hyperthyroidism (Overactive Thyroid): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/14129-hyperthyroidism

  Hyperthyroidism, also called overactive thyroid, happens when your thyroid makes and releases high levels of thyroid hormone. Hyperthyroidism is relatively rare. Approximately 1.3% of people in the United States have it. […] Hyperthyroidism is a treatable condition. Most people do well with treatment. […] Complications from untreated or undertreated hyperthyroidism include: Atrial fibrillation (Afib), Congestive heart failure, Infertility, Ischemic stroke, Osteoporosis. […] A rare and life-threatening complication of hyperthyroidism is thyroid storm (thyroid crisis or thyrotoxic crisis). It happens when your thyroid makes and releases a large amount of thyroid hormone in a short amount of time.

• #86

  https://www.nhs.uk/conditions/overactive-thyroid-hyperthyroidism/complications/

  Several complications can develop if you have an overactive thyroid (hyperthyroidism), particularly if the condition is not treated. […] Eye problems, known as thyroid eye disease or Graves’ ophthalmopathy, affect around 1 in 4 people with an overactive thyroid caused by Graves’ disease. […] If you have an overactive thyroid during pregnancy and your condition is not well controlled, it can increase the risk of: pre-eclampsia, miscarriage, premature labour and birth (before the 37th week of pregnancy), your baby having a low birthweight. […] Rarely, an undiagnosed or poorly controlled overactive thyroid can lead to a serious, life-threatening condition called a thyroid storm. […] An overactive thyroid can also increase your chances of developing: atrial fibrillation a heart condition that causes an irregular and often abnormally fast heart rate, weakened bones (osteoporosis) a condition that makes your bones fragile and more likely to break, heart failure where the heart is unable to pump blood around your body properly.

• #87 Thyroid disease

  https://womenshealth.gov/a-z-topics/thyroid-disease

  Hyperthyroidism, (hy-pur-THY-roi-diz-uhm) or overactive thyroid, causes your thyroid to make more thyroid hormone than your body needs. This speeds up many of your body’s functions, like your metabolism and heart rate. […] The most common cause of hyperthyroidism is Graves’ disease. Graves’ disease is a problem with the immune system. […] Hyperthyroidism raises your risk for osteoporosis, a condition that causes weak bones that break easily. In fact, hyperthyroidism might affect your bones before you have any of the other symptoms of the condition. This is especially true of women who have gone through menopause or who are already at high risk of osteoporosis. […] Your doctor’s choice of treatment will depend on your symptoms and the cause of your hyperthyroidism. Treatments include:

• #88 Hyperthyroidism (Overactive Thyroid): Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/14129-hyperthyroidism

  Hyperthyroidism, also called overactive thyroid, happens when your thyroid makes and releases high levels of thyroid hormone. Hyperthyroidism is relatively rare. Approximately 1.3% of people in the United States have it. […] Hyperthyroidism is a treatable condition. Most people do well with treatment. […] Complications from untreated or undertreated hyperthyroidism include: Atrial fibrillation (Afib), Congestive heart failure, Infertility, Ischemic stroke, Osteoporosis. […] A rare and life-threatening complication of hyperthyroidism is thyroid storm (thyroid crisis or thyrotoxic crisis). It happens when your thyroid makes and releases a large amount of thyroid hormone in a short amount of time.

• #89 Hyperthyroidism (overactive thyroid) | Doctor

  https://patient.info/doctor/hyperthyroidism

  Hyperthyroidism is overactivity of the thyroid gland, which results in a number of symptoms and signs. It can be primary or secondary: […] In Europe, thyrotoxicosis affects around 1 in 2,000 people annually. There is a global prevalence of 0.2 – 2.5%. Thyrotoxicosis is still under-diagnosed however – it has been shown that in people older than 65 years, undiagnosed hyperthyroidism occurs in 0.3% of people and around 2% of people aged over 65 years have subclinical hyperthyroidism. Graves’ disease in adults affects approximately 2% of women and 0.2% of men. Graves’ disease accounts for around 75% of cases. […] Subclinical hyperthyroidism occurs in around 2% of the elderly population. The most common cause of true subclinical hyperthyroidism is toxic nodular goitre, especially in the elderly. Subclinical hyperthyroidism is associated with increased risks of coronary heart disease (CHD) mortality and incident atrial fibrillation, with highest risks of CHD mortality and atrial fibrillation when thyrotropin level is lower than 0.10 mIU/L. Subclinical hyperthyroidism is also associated with an increased risk of hip and other fractures, particularly among those with TSH levels of less than 0.10 mIU/L.

• #90 Hyperthyroidism – Wikipedia

  https://en.wikipedia.org/wiki/Hyperthyroidism

  In the United States hyperthyroidism affects about 1.2% of the population. […] It occurs between two and ten times more often in women. […] The disease is more common in those over the age of 60 years. […] Subclinical hyperthyroidism modestly increases the risk of cognitive impairment and dementia.

• #91 Thyroid disease

  https://womenshealth.gov/a-z-topics/thyroid-disease

  High levels of radioiodine mean that your thyroid makes too much of the thyroid hormone. Low levels mean that your thyroid does not make enough thyroid hormone. […] Both hyperthyroidism and hypothyroidism can make it harder for you to get pregnant. This is because problems with the thyroid hormone can upset the balance of the hormones that cause ovulation. […] Pregnancy-related hormones raise the level of thyroid hormones in the blood. Thyroid hormones are necessary for the baby’s brain development while in the womb. […] Uncontrolled hyperthyroidism and hypothyroidism can cause problems for both mother and baby.

• #92 Understanding Hyperthyroidism ( Overactive Thyroid Gland ): Causes, Symptoms, and Treatment Options | The American Journal of Patient Health Info

  https://ajphi.org/ajphi/article/view/38

  Hyperthyroidism occurs when you have an excess amount of thyroid hormone produced by your thyroid gland. […] The most common cause of hyperthyroidism is Graves disease. It is an autoimmune condition where the body produces antibodies that stimulate the thyroid. […] Graves disease (GD) is the most common cause of hyperthyroidism in developed countries. It is more commonly seen between people of 30 and 60 years, with 5-10 times increased frequency in women. About 79% of the people are genetically predisposed, and about 21% of them have some environmental factors as a risk factor. […] Hyperthyroidism can potentially impact fertility in both men and women. However, the extent of its effects can vary depending on factors such as the severity of the condition and how well it is managed. […] Hyperthyroidism can develop during pregnancy due to changes in hormone levels and immune function. This condition is known as gestational transient thyrotoxicosis and typically resolves after childbirth.

• #93

  https://www.nhs.uk/conditions/overactive-thyroid-hyperthyroidism/complications/

  Several complications can develop if you have an overactive thyroid (hyperthyroidism), particularly if the condition is not treated. […] Eye problems, known as thyroid eye disease or Graves’ ophthalmopathy, affect around 1 in 4 people with an overactive thyroid caused by Graves’ disease. […] If you have an overactive thyroid during pregnancy and your condition is not well controlled, it can increase the risk of: pre-eclampsia, miscarriage, premature labour and birth (before the 37th week of pregnancy), your baby having a low birthweight. […] Rarely, an undiagnosed or poorly controlled overactive thyroid can lead to a serious, life-threatening condition called a thyroid storm. […] An overactive thyroid can also increase your chances of developing: atrial fibrillation a heart condition that causes an irregular and often abnormally fast heart rate, weakened bones (osteoporosis) a condition that makes your bones fragile and more likely to break, heart failure where the heart is unable to pump blood around your body properly.

• #94 Thyroid Disorders, Active Component, U.S. Armed Forces, 2008–2017 | Health.mil

  https://health.mil/News/Articles/2018/12/01/Thyroid-Disorders

  This analysis describes the incidence and prevalence of five thyroid disorders (goiter, thyrotoxicosis, primary/not otherwise specified [NOS] hypothyroidism, thyroiditis, and other disorders of the thyroid) among active component service members between 2008 and 2017. […] The prevalence of hyperthyroidism in the U.S. is estimated to be 1.3% according to data from the NHANES-III, with the lowest prevalence observed among Mexican Americans and the highest among non-Hispanic whites. […] Hyperthyroidism and hypothyroidism can significantly degrade the military operational capabilities of affected service members due to the various symptoms of the disorders. […] Although thyroid disorders are treatable, hypothyroidism and hyperthyroidism can result in periods of non-deployability, temporary duty profile, or need for medical waiver at the time of diagnosis or if there is a disruption in treatment. More severe cases of hyperthyroidism can take up to 1 year to stabilize, resulting in significant periods of limited deployability. […] In contrast with a previous MSMR report documenting increases in thyroid disorder diagnoses among active component service members between 2002 and 2011, the results of the current analysis indicate that the incidence of thyroid disorders remained stable or decreased between 2008 and 2017.

• #95 Thyroid Disorders, Active Component, U.S. Armed Forces, 2008–2017 | Health.mil

  https://health.mil/News/Articles/2018/12/01/Thyroid-Disorders

  This analysis describes the incidence and prevalence of five thyroid disorders (goiter, thyrotoxicosis, primary/not otherwise specified [NOS] hypothyroidism, thyroiditis, and other disorders of the thyroid) among active component service members between 2008 and 2017. […] The prevalence of hyperthyroidism in the U.S. is estimated to be 1.3% according to data from the NHANES-III, with the lowest prevalence observed among Mexican Americans and the highest among non-Hispanic whites. […] Hyperthyroidism and hypothyroidism can significantly degrade the military operational capabilities of affected service members due to the various symptoms of the disorders. […] Although thyroid disorders are treatable, hypothyroidism and hyperthyroidism can result in periods of non-deployability, temporary duty profile, or need for medical waiver at the time of diagnosis or if there is a disruption in treatment. More severe cases of hyperthyroidism can take up to 1 year to stabilize, resulting in significant periods of limited deployability. […] In contrast with a previous MSMR report documenting increases in thyroid disorder diagnoses among active component service members between 2002 and 2011, the results of the current analysis indicate that the incidence of thyroid disorders remained stable or decreased between 2008 and 2017.

• #96 Thyroid Disorders, Active Component, U.S. Armed Forces, 2008–2017 | Health.mil

  https://health.mil/News/Articles/2018/12/01/Thyroid-Disorders

  This analysis describes the incidence and prevalence of five thyroid disorders (goiter, thyrotoxicosis, primary/not otherwise specified [NOS] hypothyroidism, thyroiditis, and other disorders of the thyroid) among active component service members between 2008 and 2017. […] The prevalence of hyperthyroidism in the U.S. is estimated to be 1.3% according to data from the NHANES-III, with the lowest prevalence observed among Mexican Americans and the highest among non-Hispanic whites. […] Hyperthyroidism and hypothyroidism can significantly degrade the military operational capabilities of affected service members due to the various symptoms of the disorders. […] Although thyroid disorders are treatable, hypothyroidism and hyperthyroidism can result in periods of non-deployability, temporary duty profile, or need for medical waiver at the time of diagnosis or if there is a disruption in treatment. More severe cases of hyperthyroidism can take up to 1 year to stabilize, resulting in significant periods of limited deployability. […] In contrast with a previous MSMR report documenting increases in thyroid disorder diagnoses among active component service members between 2002 and 2011, the results of the current analysis indicate that the incidence of thyroid disorders remained stable or decreased between 2008 and 2017.

• #97 Thyroid Disorders, Active Component, U.S. Armed Forces, 2008–2017 | Health.mil

  https://health.mil/News/Articles/2018/12/01/Thyroid-Disorders?page=3

  This analysis describes the incidence and prevalence of five thyroid disorders (goiter, thyrotoxicosis, primary/not otherwise specified [NOS] hypothyroidism, thyroiditis, and other disorders of the thyroid) among active component service members between 2008 and 2017. […] The prevalence of hyperthyroidism in the U.S. is estimated to be 1.3% according to data from the NHANES-III, with the lowest prevalence observed among Mexican Americans and the highest among non-Hispanic whites. Hyperthyroidism can lead to thyrotoxicosis, a term that refers to having an excess of thyroid hormone in the body from any cause. […] Although thyroid disorders are treatable, hypothyroidism and hyperthyroidism can result in periods of non-deployability, temporary duty profile, or need for medical waiver at the time of diagnosis or if there is a disruption in treatment. More severe cases of hyperthyroidism can take up to 1 year to stabilize, resulting in significant periods of limited deployability. […] In contrast with a previous MSMR report documenting increases in thyroid disorder diagnoses among active component service members between 2002 and 2011, the results of the current analysis indicate that the incidence of thyroid disorders remained stable or decreased between 2008 and 2017.

• #98 Hyperthyroidism Statistics: Global and U.S. Overview, Types, Trends, and Complications – Broken English MD

  https://brokenenglishmd.com/hyperthyroidism-statistics-global-and-u-s-overview-types-trends-and-complications/

  In summary, hyperthyroidism is a relatively common condition (affecting about 1% of people in the U.S. and globally), especially among women and older adults. Thanks to iodized salt and advanced medical care, most cases are manageable and curable. The data show improved trends in reducing severe outcomes. Still, hyperthyroidism can significantly impact quality of life and health if not treated – causing heart, bone, and metabolic complications. With prompt diagnosis (through recognition of symptoms and confirmatory lab tests) and appropriate therapy (medications, radioactive iodine, or surgery), patients can expect to fully recover and lead normal, healthy lives.

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